methadone has been researched along with Psychoses, Drug in 16 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Over 2/3 of methadone-substituted patients suffer from chronic hepatitis C but a history of psychiatric disorders or drug addiction is still seen as a contraindication for IFN-alpha because of a possible increased risk of severe psychiatric side effects such as depression, suicide attempts or psychotic episodes." | 3.70 | Psychosis in a methadone-substituted patient during interferon-alpha treatment of hepatitis C. ( Boetsch, T; Laakmann, G; Schäfer, M, 2000) |
| "The scale of drug dependence has grown dramatically in the past quarter-century." | 2.40 | WHO Expert Committee on Drug Dependence. Thirtieth report. ( , 1998) |
| "A review of the literature of multiple drug abuse involving two or more drug categories where at least one is a nonopiate, nonalcoholic substance (MDA NONA) suggested the possibility that sedative-hypnotics were the culpable agent for neuropsychological deficits in this group." | 2.36 | Multiple drug abuse involving nonopiate, nonalcoholic substances. II. Physical damage, long-term psychological effects and treatment approaches and success. ( Kornblith, AB, 1981) |
| "Methadone is a typical mu-opioid receptor agonist that is widely used for maintenance and detoxification treatment of opiate-dependent patients." | 1.29 | Methadone withdrawal psychosis. ( Galynker, II; Levinson, I; Rosenthal, RN, 1995) |
| "Naloxone pretreatment on doses up to 20 mg/kg was not effective in antagonizing PCP-induced behavioral effects." | 1.26 | Phencyclidine-induced stereotype in rats: effects of methadone, apomorphine, and naloxone. ( Kogan, MJ; Mulè, SJ; Verebey, K, 1981) |
| "The origin of the psychiatric illnesses observed in drug abusers is often unclear." | 1.26 | Development of psychiatric illness in drug abusers. Possible role of drug preference. ( Mc Lellan, AT; O'Brien, CP; Woody, GE, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shprecher, DR | 1 |
| Flanigan, KM | 1 |
| Smith, AG | 1 |
| Smith, SM | 1 |
| Schenkenberg, T | 1 |
| Steffens, J | 1 |
| Woody, GE | 3 |
| McLellan, AT | 1 |
| O'Brien, CP | 3 |
| Verebey, K | 1 |
| Kogan, MJ | 1 |
| Mulè, SJ | 1 |
| Kornblith, AB | 1 |
| Uhde, TW | 1 |
| Redmond, DE | 1 |
| Kleber, HD | 1 |
| Levinson, I | 1 |
| Galynker, II | 1 |
| Rosenthal, RN | 1 |
| Schäfer, M | 1 |
| Boetsch, T | 1 |
| Laakmann, G | 1 |
| Shreeram, SS | 1 |
| McDonald, T | 1 |
| Dennison, S | 1 |
| Mc Lellan, AT | 1 |
| Greenstein, R | 1 |
| Schmalstieg, WJ | 1 |
| Hayden, JW | 1 |
| Comstock, EG | 1 |
| Benforado, JM | 1 |
| Ruiz, P | 1 |
| Lowinson, JH | 1 |
| Marcus, N | 1 |
| Langrod, J | 1 |
| DeBoer, L | 1 |
| Salzman, B | 1 |
3 reviews available for methadone and Psychoses, Drug
| Article | Year |
|---|---|
Multiple drug abuse involving nonopiate, nonalcoholic substances. II. Physical damage, long-term psychological effects and treatment approaches and success.
Topics: Amphetamines; Arrhythmias, Cardiac; Attention; Brain Damage, Chronic; Follow-Up Studies; Humans; Hyp | 1981 |
WHO Expert Committee on Drug Dependence. Thirtieth report.
Topics: Acute Disease; Cost of Illness; Cost-Benefit Analysis; Health Policy; Humans; Methadone; Narcotics; | 1998 |
The opiates and their derivatives.
Topics: Codeine; Dose-Response Relationship, Drug; Drug Tolerance; Hallucinogens; Humans; Methadone; Morphin | 1973 |
1 trial available for methadone and Psychoses, Drug
| Article | Year |
|---|---|
Multimodality treatment of narcotic addiction: an overview.
Topics: Ambulatory Care; Behavior Therapy; Clinical Trials as Topic; Dextropropoxyphene; Double-Blind Method | 1978 |
12 other studies available for methadone and Psychoses, Drug
| Article | Year |
|---|---|
Clinical and diagnostic features of delayed hypoxic leukoencephalopathy.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Brain; Cocaine; Cognition Disorders; Depressive Disorder | 2008 |
Treatment of behavioral and psychiatric problems associated with opiate dependence.
Topics: Antisocial Personality Disorder; Behavior Therapy; Combined Modality Therapy; Humans; Mental Disorde | 1984 |
Phencyclidine-induced stereotype in rats: effects of methadone, apomorphine, and naloxone.
Topics: Animals; Apomorphine; Brain Chemistry; Disease Models, Animal; Humans; Male; Methadone; Motor Activi | 1981 |
Psychosis in the opioid addicted patient: assessment and treatment.
Topics: Adult; Chlorpromazine; Diagnosis, Differential; Double-Blind Method; Haloperidol; Heroin Dependence; | 1982 |
Methadone withdrawal psychosis.
Topics: Adult; Female; Follow-Up Studies; Haloperidol; Humans; Male; Methadone; Middle Aged; Opioid-Related | 1995 |
Psychosis in a methadone-substituted patient during interferon-alpha treatment of hepatitis C.
Topics: Adult; Antiviral Agents; Contraindications; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Me | 2000 |
Psychosis after ultrarapid opiate detoxification.
Topics: Alprazolam; Benzodiazepines; Drug Administration Schedule; Female; Humans; Hydrocodone; Methadone; M | 2001 |
Development of psychiatric illness in drug abusers. Possible role of drug preference.
Topics: Adult; Amphetamines; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Depression; Hallucinogens; | 1979 |
Propoxyphene napsylate detoxification.
Topics: Adult; Dextropropoxyphene; Dose-Response Relationship, Drug; Heroin Dependence; Humans; Male; Methad | 1975 |
The treatment of drug abuse: update for the physician.
Topics: Adolescent; Adult; Aged; Amphetamine; Barbiturates; Child; Cocaine; Emergencies; Female; Humans; Hyp | 1974 |
Treatment of drug addiction in two different communities. Comparative review.
Topics: Adolescent; Adult; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; New York; Outpat | 1973 |
What we're learning about methadone and some other addiction programs.
Topics: Heroin; Heroin Dependence; Humans; Methadone; Methods; Parent-Child Relations; Psychoses, Substance- | 1973 |