methadone has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 3 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Physicians should be aware of the potential interaction between voriconazole, esomeprazole and methadone leading to arrhythmia." | 3.77 | Ventricular bigeminy associated with voriconazole, methadone and esomeprazole. ( Herbrecht, R; Kemmel, V; Levêque, D; Nivoix, Y; Scholler, J, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friesen, C | 1 |
| Roscher, M | 1 |
| Hormann, I | 1 |
| Fichtner, I | 1 |
| Alt, A | 1 |
| Hilger, RA | 1 |
| Debatin, KM | 1 |
| Miltner, E | 1 |
| Singh, A | 1 |
| Jayanthan, A | 1 |
| Farran, A | 1 |
| Elwi, AN | 1 |
| Kim, SW | 1 |
| Farran, P | 1 |
| Narendran, A | 1 |
| Scholler, J | 1 |
| Nivoix, Y | 1 |
| Herbrecht, R | 1 |
| Kemmel, V | 1 |
| Levêque, D | 1 |
3 other studies available for methadone and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Cell death sensitization of leukemia cells by opioid receptor activation.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics, Opioid; Animals; Antibiotics, Antineopla | 2013 |
Induction of apoptosis in pediatric acute lymphoblastic leukemia (ALL) cells by the therapeutic opioid methadone and effective synergy with Bcl-2 inhibition.
Topics: Age Factors; Age of Onset; Analgesics, Opioid; Antineoplastic Combined Chemotherapy Protocols; Apopt | 2011 |
Ventricular bigeminy associated with voriconazole, methadone and esomeprazole.
Topics: Adult; Analgesics, Opioid; Antifungal Agents; Arrhythmias, Cardiac; Drug Interactions; Esomeprazole; | 2011 |