Page last updated: 2024-10-30

methadone and Postoperative Complications

methadone has been researched along with Postoperative Complications in 19 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of ondansetron 4 mg was compared with metoclopramide 10 mg for the prevention of post-operative nausea and vomiting in patients after major gynaecological abdominal surgery."9.08Comparison of ondansetron and metoclopramide for the prevention of post-operative nausea and vomiting after major gynaecological surgery. ( Chen, PP; Chui, PT; Gin, T, 1996)
"Postoperatively, he developed OIC and Ogilvie syndrome, then following treatment with methylnaltrexone experienced an acute bowel perforation."5.51Methylnaltrexone-Associated Bowel Perforation in Postoperative Opioid-Induced Constipation and Ogilvie Syndrome: A Case Report. ( Blackney, KA; Edwards, DA; Kamdar, NV; Liu, CA, 2019)
"The efficacy of ondansetron 4 mg was compared with metoclopramide 10 mg for the prevention of post-operative nausea and vomiting in patients after major gynaecological abdominal surgery."5.08Comparison of ondansetron and metoclopramide for the prevention of post-operative nausea and vomiting after major gynaecological surgery. ( Chen, PP; Chui, PT; Gin, T, 1996)
"As clonidine was the most effective drug in terms of preservation of pre-operative lung function, it may be clinically advantageous in post-thoracotomy patients."2.71Epidural clonidine, bupivacaine and methadone as the sole analgesic agent after thoracotomy for lung resection. ( Drenger, B; Gozal, Y; Matot, I; Shauli, A; Weissman, C, 2004)
"Postoperative pain is not adequately managed in greater than 40% of surgical patients and is a high priority for perioperative research."2.66Intraoperative methadone administration and postoperative pain control: a systematic review and meta-analysis. ( D'Souza, RS; Gurrieri, C; Johnson, RL; Warner, N; Wittwer, E, 2020)
"Postoperatively, he developed OIC and Ogilvie syndrome, then following treatment with methylnaltrexone experienced an acute bowel perforation."1.51Methylnaltrexone-Associated Bowel Perforation in Postoperative Opioid-Induced Constipation and Ogilvie Syndrome: A Case Report. ( Blackney, KA; Edwards, DA; Kamdar, NV; Liu, CA, 2019)
"Infant delirium is an under-recognized clinical entity in neonatal intensive care, and earlier identification and treatment could minimize morbidities associated with this condition."1.46A case of infant delirium in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB, 2017)
"The use of epidural methadone for postoperative pain relief is advocated, both in view of its analgesic potency and of the low incidence of urinary disturbances."1.27Urinary function during epidural analgesia with methadone and morphine in post-cesarean section patients. ( Drenger, B; Evron, S; Magora, F; Samueloff, A; Simon, A, 1985)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19908 (42.11)18.7374
1990's3 (15.79)18.2507
2000's3 (15.79)29.6817
2010's3 (15.79)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Komatsu, R1
Nash, MG1
Wu, J1
Dinges, EM1
Delgado, CM1
Bollag, LA1
D'Souza, RS1
Gurrieri, C1
Johnson, RL1
Warner, N1
Wittwer, E1
Blackney, KA1
Kamdar, NV1
Liu, CA1
Edwards, DA1
Edwards, LE1
Hutchison, LB1
Hornik, CD1
Smith, PB1
Cotten, CM1
Bidegain, M1
Robaeys, G1
Nevens, F1
Stärkel, P1
Colle, I1
Van Eyken, P1
Bruckers, L1
Van Ranst, M1
Buntinx, F1
Durán, E1
Salvo, S1
Gil, J1
Sanjoaquín, I1
Matot, I1
Drenger, B2
Weissman, C1
Shauli, A1
Gozal, Y1
Lin, YC1
Golianu, B1
van den Brink, RB1
Wilmink, JM1
Vreeken, J1
Rakarić-Poznanović, M1
Ranić, V1
Snur, I1
Chen, PP1
Chui, PT1
Gin, T1
Rubenstein, RB2
Spira, I1
Wolff, WI1
Mbawa, N1
Norris, JV1
Don, HF1
de Leon-Casasola, OA1
Lema, MJ1
Evron, S1
Samueloff, A1
Simon, A1
Magora, F1
Hargrave, SA1
Legge, JS1
Palmer, KN1
Gozon, F1
Amante, S1
Bozzetti, A1

Reviews

1 review available for methadone and Postoperative Complications

ArticleYear
Intraoperative methadone administration and postoperative pain control: a systematic review and meta-analysis.
    Pain, 2020, Volume: 161, Issue:2

    Topics: Airway Extubation; Analgesics, Opioid; Humans; Hypoxia; Intraoperative Care; Length of Stay; Methado

2020

Trials

2 trials available for methadone and Postoperative Complications

ArticleYear
Epidural clonidine, bupivacaine and methadone as the sole analgesic agent after thoracotomy for lung resection.
    Anaesthesia, 2004, Volume: 59, Issue:9

    Topics: Adult; Aged; Analgesia, Epidural; Analgesics; Bupivacaine; Clonidine; Double-Blind Method; Female; H

2004
Comparison of ondansetron and metoclopramide for the prevention of post-operative nausea and vomiting after major gynaecological surgery.
    European journal of anaesthesiology, 1996, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Analgesics, Opioid; Antiemetics; Double-Blind Method; Female; Humans; Hysterectom

1996

Other Studies

16 other studies available for methadone and Postoperative Complications

ArticleYear
Prediction of postoperative respiratory depression and respiratory complications in patients on preoperative methadone.
    Journal of anesthesia, 2023, Volume: 37, Issue:1

    Topics: Humans; Methadone; Postoperative Complications; Respiration Disorders; Respiratory Insufficiency; Re

2023
Methylnaltrexone-Associated Bowel Perforation in Postoperative Opioid-Induced Constipation and Ogilvie Syndrome: A Case Report.
    A&A practice, 2019, Jan-15, Volume: 12, Issue:2

    Topics: Analgesics, Opioid; Colonic Pseudo-Obstruction; Constipation; Decompression, Surgical; Humans; Hydro

2019
A case of infant delirium in the neonatal intensive care unit.
    Journal of neonatal-perinatal medicine, 2017, Volume: 10, Issue:1

    Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acid

2017
Previous intravenous substance use and outcome of liver transplantation in patients with chronic hepatitis C infection.
    Transplantation proceedings, 2009, Volume: 41, Issue:2

    Topics: Biopsy; Female; Graft Rejection; Graft Survival; Hepatitis C, Chronic; Humans; Immunosuppressive Age

2009
[Pneumonia and bacteremia due to Neisseria mucosa in a human immunodeficient virus seropositive patient parenteral drug abuser].
    Enfermedades infecciosas y microbiologia clinica, 2011, Volume: 29, Issue:3

    Topics: Adult; Bacteremia; Heart Valve Prosthesis Implantation; Heroin Dependence; HIV Infections; Humans; I

2011
Anesthesia and pain management for pediatric patients with dystrophic epidermolysis bullosa.
    Journal of clinical anesthesia, 2006, Volume: 18, Issue:4

    Topics: Adolescent; Anesthesia, General; Child; Child, Preschool; Conscious Sedation; Epidermolysis Bullosa

2006
[The importance of an accurate preoperative anamnesis].
    Nederlands tijdschrift voor geneeskunde, 1982, Oct-02, Volume: 126, Issue:40

    Topics: Coma; Diuretics; Drug Synergism; Humans; Kidney Tubules; Lithium; Male; Medical History Taking; Meth

1982
[Multiorgan dysfunction syndrome (MODS) caused by long bone fractures in young persons].
    Lijecnicki vjesnik, 1995, Volume: 117 Suppl 2

    Topics: Adult; Analgesia, Epidural; Analgesics; Bupivacaine; Fractures, Bone; Humans; Leg; Leg Injuries; Met

1995
Management of surgical problems in patients on methadone maintenance.
    American journal of surgery, 1976, Volume: 131, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Cocaine; Female; Heroin Dependence; Humans; Hydromorph

1976
Excluded loop syndrome: a complication of jejuno-ileal bypass for obesity.
    The British journal of surgery, 1978, Volume: 65, Issue:9

    Topics: Humans; Ileum; Jejunum; Male; Methadone; Middle Aged; Obesity; Postoperative Complications

1978
Prolonged depression of respiratory rate following methadone analgesia.
    Anesthesiology, 1976, Volume: 45, Issue:3

    Topics: Aged; Anesthesia, General; Aortic Valve; Aortic Valve Stenosis; Depression, Chemical; Female; Humans

1976
Epidural sufentanil for acute pain control in a patient with extreme opioid dependency.
    Anesthesiology, 1992, Volume: 76, Issue:5

    Topics: Adult; Analgesia, Epidural; Analgesics; Female; Fentanyl; Humans; Methadone; Pain, Postoperative; Po

1992
Urinary function during epidural analgesia with methadone and morphine in post-cesarean section patients.
    Pain, 1985, Volume: 23, Issue:2

    Topics: Adult; Anesthesia, Epidural; Cesarean Section; Female; Humans; Methadone; Morphine; Pain, Postoperat

1985
Postoperative ventilatory failure in a patient with primary alveolar hypoventilation. A case report.
    British journal of anaesthesia, 1973, Volume: 45, Issue:1

    Topics: Appendectomy; Carbon Dioxide; Cheyne-Stokes Respiration; Female; Humans; Hydrogen-Ion Concentration;

1973
[Cause and treatment of spasticity following halothane anesthesia].
    Der Anaesthesist, 1969, Volume: 18, Issue:8

    Topics: Adult; Analgesics; Anesthesia, Inhalation; Benperidol; Body Temperature; Diazepam; Halothane; Humans

1969
[Research on the placebo effect in postoperative pain].
    Rassegna internazionale di clinica e terapia, 1969, Aug-31, Volume: 49, Issue:16

    Topics: Female; Humans; Male; Methadone; Pain; Placebos; Postoperative Complications; Pyrazoles; Sulfonic Ac

1969