methadone has been researched along with Poisoning in 83 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the impact of this change and of the withdrawal of thioridazine in 2000 on antipsychotic-related fatal poisoning, we reviewed all such deaths in England and Wales 1993-2013 recorded on the Office for National Statistics drug poisoning deaths database." | 8.93 | Antipsychotic-related fatal poisoning, England and Wales, 1993-2013: impact of the withdrawal of thioridazine. ( Flanagan, RJ; Handley, S; Patel, MX, 2016) |
| " Methadone poisoning was the most severe." | 8.31 | Opioid poisoning in Newcastle over the last three decades: From heroin to prescription opioids. ( Isbister, GK; Isoardi, KZ, 2023) |
| "Eighty patients with methadone poisoning were enrolled, with median age of three years (range: 0." | 8.02 | A study of the effectiveness of naltrexone in preventing recurrence of methadone poisoning in opioid-naive children. ( Farnaghi, F; Gholami, N; Hassanian-Moghaddam, H; McDonald, R; Saberi, M; Zamani, N, 2021) |
| "A hospital-based retrospective case series analysis of admissions related to prescription drug poisonings associated with methadone, opioid analgesics, antidepressants or benzodiazepines for hospitals in Clark County, Nevada between 2009 and 2013 was employed." | 7.85 | Retrospective case series analysis of characteristics and trends in unintentional pharmaceutical drug poisoning by methadone, opioid analgesics, antidepressants and benzodiazepines in Clark County, NV 2009-13. ( Bruno, T; Pharr, JR, 2017) |
| "The article deals with the materials, which have been received in the process of the examination and treatment of 44 patients with acute severe methadone poisonings." | 7.78 | [Using of reamberin for correction of free radicals disturbances in patients with acute severe methadone poisonings]. ( Batotsyrenov, BV; Kuznetsov, OA; Loladze, AT; Shilov, VV; Vasil'ev, SA, 2012) |
| "To report an accidental contamination of antibiotic suspension by methadone that occurred in a retail Canadian pharmacy, leading to severe poisoning in a young child." | 7.70 | Contamination of antibiotics resulting in severe pediatric methadone poisoning. ( Kapur, BM; Koren, G; Lalkin, A; Verjee, ZH, 1999) |
| "I report the successful treatment of severe infantile opiate poisoning with continuous naloxone infusions." | 7.67 | Continuous naloxone infusion for opiate poisoning in infancy. ( Tenenbein, M, 1984) |
| "Acute poisoning is commonly seen with pharmaceutical substance or pesticides." | 5.72 | Fatalities Due to Poisoning with Aluminum Phosphide (Rice Pill) and Methadone. ( Ahadi, M; Astaraki, P; Honardoost, V; Salehinejad, F, 2022) |
| "To evaluate the impact of this change and of the withdrawal of thioridazine in 2000 on antipsychotic-related fatal poisoning, we reviewed all such deaths in England and Wales 1993-2013 recorded on the Office for National Statistics drug poisoning deaths database." | 4.93 | Antipsychotic-related fatal poisoning, England and Wales, 1993-2013: impact of the withdrawal of thioridazine. ( Flanagan, RJ; Handley, S; Patel, MX, 2016) |
| " Methadone poisoning was the most severe." | 4.31 | Opioid poisoning in Newcastle over the last three decades: From heroin to prescription opioids. ( Isbister, GK; Isoardi, KZ, 2023) |
| "Eighty patients with methadone poisoning were enrolled, with median age of three years (range: 0." | 4.02 | A study of the effectiveness of naltrexone in preventing recurrence of methadone poisoning in opioid-naive children. ( Farnaghi, F; Gholami, N; Hassanian-Moghaddam, H; McDonald, R; Saberi, M; Zamani, N, 2021) |
| "A hospital-based retrospective case series analysis of admissions related to prescription drug poisonings associated with methadone, opioid analgesics, antidepressants or benzodiazepines for hospitals in Clark County, Nevada between 2009 and 2013 was employed." | 3.85 | Retrospective case series analysis of characteristics and trends in unintentional pharmaceutical drug poisoning by methadone, opioid analgesics, antidepressants and benzodiazepines in Clark County, NV 2009-13. ( Bruno, T; Pharr, JR, 2017) |
| "Methadone is the most common pharmaceutical causing fatal poisoning and a common cause of intensive care unit admissions in young children in the UK." | 3.83 | Severe and fatal pharmaceutical poisoning in young children in the UK. ( Anderson, M; Eddleston, M; Hawkins, L; Thomas, SH; Thompson, JP; Vale, JA, 2016) |
| "The article deals with the materials, which have been received in the process of the examination and treatment of 44 patients with acute severe methadone poisonings." | 3.78 | [Using of reamberin for correction of free radicals disturbances in patients with acute severe methadone poisonings]. ( Batotsyrenov, BV; Kuznetsov, OA; Loladze, AT; Shilov, VV; Vasil'ev, SA, 2012) |
| "Methadone is used worldwide for the treatment of heroin addiction; however, fatal poisonings are increasingly reported." | 3.77 | Interindividual variability in the prevalence of OPRM1 and CYP2B6 gene variations may identify drug-susceptible populations. ( Bunten, H; Liang, WJ; Osselton, D; Pounder, DJ; Seneviratne, C, 2011) |
| " Despite large inter-individual variability in methadone toxicokinetics and toxicodynamics, TK/TD relationships would be helpful for providing quantitative data regarding the respiratory response to methadone in poisonings." | 3.74 | Case report: quantification of methadone-induced respiratory depression using toxicokinetic/toxicodynamic relationships. ( Bardin, C; Baud, FJ; Bloch, V; Chast, F; Declèves, X; Mégarbane, B, 2007) |
| "There were 92 poisoning deaths involving opioids: morphine in 33, methadone in 31, dextropropoxyphene in 16, and codeine/dihydrocodeine in 12." | 3.73 | Opioid poisoning deaths in New Zealand (2001-2002). ( Fountain, J; Reith, D; Tilyard, M, 2005) |
| " Poisonings with buprenorphine are more frequent but ingestions of methadone are often more severe (p = 0." | 3.73 | [Accidental ingestion of methadone and buprenorphine by children. A case review of the Lille Poison Centre between 1995 and 2005]. ( Cezard, C; Mathieu-Nolf, M; Nisse, P; Peucelle, D, 2006) |
| "To report an accidental contamination of antibiotic suspension by methadone that occurred in a retail Canadian pharmacy, leading to severe poisoning in a young child." | 3.70 | Contamination of antibiotics resulting in severe pediatric methadone poisoning. ( Kapur, BM; Koren, G; Lalkin, A; Verjee, ZH, 1999) |
| "Drug-related fatal poisonings were analysed in Hamburg from 1990 to 30th June 1999 with special attention to the role of methadone." | 3.70 | Methadone-related fatalities in Hamburg 1990-1999: implications for quality standards in maintenance treatment? ( Heinemann, A; Iwersen-Bergmann, S; Püschel, K; Schmoldt, A; Stein, S, 2000) |
| "I report the successful treatment of severe infantile opiate poisoning with continuous naloxone infusions." | 3.67 | Continuous naloxone infusion for opiate poisoning in infancy. ( Tenenbein, M, 1984) |
| " These episodes were characterized by apnea plus some combination of color change, choking or gagging, and abnormal muscle tone." | 3.67 | Parental administration of chemical agents: a cause of apparent life-threatening events. ( Altemeier, WA; Campbell, PW; Hickson, GB; Martin, ED, 1989) |
| "The drug levels in postmortem specimens from 12 cases of poisoning involving methadone have been determined using a general toxicological extraction method." | 3.65 | The toxicology of twelve cases of death involving methadone: examination of postmortem specimens. ( Nelson, PE; Selkirk, RC, 1975) |
| "Methadone was found to be the most toxic of the opioids; doses as low as a single tablet can lead to death." | 2.43 | Are one or two dangerous? Opioid exposure in toddlers. ( Sachdeva, DK; Stadnyk, JM, 2005) |
| "Methadone is a synthetic opioid, used both as an analgesic in severe pain relief and now mainly in the treatment of opiate dependence." | 2.42 | The effects of methadone and its role in fatalities. ( Corkery, JM; Ghodse, AH; Oyefeso, A; Schifano, F, 2004) |
| "The average duration of opioid use disorder was 8." | 1.56 | Non-Opioid Substances Acute Poisonings with Suicidal Intent in Patients with Opioid Use Disorder. ( Babulovska, A; Simonovska, NK; Stefanovska, VV, 2020) |
| "Poisoning was the second leading mechanism of injury deaths in Norway from 2003 to 2012, causing between 424 and 496 deaths each year." | 1.43 | Deaths by poisoning in Norway 2003-2012. ( Andrew, E; Gjertsen, F; Wigen Skjerdal, J, 2016) |
| "Poisoning is the leading cause of injury death in the United States (1)." | 1.40 | Drug-poisoning Deaths Involving Opioid Analgesics: United States, 1999-2011. ( Chen, LH; Hedegaard, H; Warner, M, 2014) |
| "Methadone poisonings were associated with accidental overdoses with the drug concentration in blood remaining within a therapeutic range." | 1.38 | Comparison of fatal poisonings by prescription opioids. ( Häkkinen, M; Launiainen, T; Ojanperä, I; Vuori, E, 2012) |
| "In a cohort of 501 drug abusers admitted to treatment in the period 1981-1991, mortality has been calculated as incidence rates." | 1.34 | Fatal overdoses and deaths by other causes in a cohort of Norwegian drug abusers--a competing risk approach. ( Amundsen, EJ; Kielland, KB; Ødegård, E, 2007) |
| " The interpretation of blood methadone concentrations alone or combined with other psychoactive drugs requires consideration of the subject's potential chronic use of and tolerance to the drug." | 1.34 | Methadone toxicity fatalities: a review of medical examiner cases in a large metropolitan area. ( Corey, TS; Hunsaker Iii, JC; Shields, LB; Stewart, D; Ward, MK, 2007) |
| "Methadone alone was found to be the cause of death in 50% more cases in 1989 than in 1981." | 1.29 | Methadone and drug addicts. ( Kringsholm, B; Steentoft, A; Worm, K, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (44.58) | 18.7374 |
| 1990's | 5 (6.02) | 18.2507 |
| 2000's | 24 (28.92) | 29.6817 |
| 2010's | 12 (14.46) | 24.3611 |
| 2020's | 5 (6.02) | 2.80 |
| Authors | Studies |
|---|---|
| Astaraki, P | 1 |
| Ahadi, M | 1 |
| Salehinejad, F | 1 |
| Honardoost, V | 1 |
| Isoardi, KZ | 1 |
| Isbister, GK | 1 |
| Rege, SV | 1 |
| Ngo, DA | 1 |
| Ait-Daoud, N | 1 |
| Rizer, J | 1 |
| Sharma, S | 1 |
| Holstege, CP | 1 |
| Simonovska, NK | 1 |
| Stefanovska, VV | 1 |
| Babulovska, A | 1 |
| Gholami, N | 1 |
| Farnaghi, F | 1 |
| Saberi, M | 1 |
| Zamani, N | 3 |
| McDonald, R | 1 |
| Hassanian-Moghaddam, H | 3 |
| Argo, A | 1 |
| Spatola, GF | 1 |
| Zerbo, S | 1 |
| Sortino, C | 1 |
| Lanzarone, A | 1 |
| Uzzo, ML | 1 |
| Pitruzzella, A | 1 |
| Farè, F | 1 |
| Roda, G | 1 |
| Gambaro, V | 1 |
| Procaccianti, P | 1 |
| Karch, SB | 2 |
| Sheibani, M | 1 |
| Rahimi, M | 1 |
| Shadnia, S | 1 |
| Pajoumand, A | 1 |
| Sarjami, S | 1 |
| Chen, LH | 1 |
| Hedegaard, H | 1 |
| Warner, M | 1 |
| Torrents, R | 1 |
| Picot, C | 1 |
| Glaizal, M | 1 |
| Courne, MA | 1 |
| Schmitt, C | 1 |
| Richard, N | 1 |
| Simon, N | 1 |
| Cardona, F | 1 |
| de Haro, L | 1 |
| Handley, S | 1 |
| Patel, MX | 1 |
| Flanagan, RJ | 1 |
| Wigen Skjerdal, J | 1 |
| Andrew, E | 1 |
| Gjertsen, F | 1 |
| Anderson, M | 1 |
| Hawkins, L | 1 |
| Eddleston, M | 1 |
| Thompson, JP | 1 |
| Vale, JA | 1 |
| Thomas, SH | 1 |
| Bruno, T | 1 |
| Pharr, JR | 1 |
| Bailey, JE | 1 |
| Campagna, E | 1 |
| Dart, RC | 1 |
| Bunten, H | 1 |
| Liang, WJ | 1 |
| Pounder, DJ | 1 |
| Seneviratne, C | 1 |
| Osselton, D | 1 |
| Shilov, VV | 1 |
| Vasil'ev, SA | 1 |
| Batotsyrenov, BV | 1 |
| Loladze, AT | 1 |
| Kuznetsov, OA | 1 |
| Häkkinen, M | 1 |
| Launiainen, T | 1 |
| Vuori, E | 1 |
| Ojanperä, I | 1 |
| Caplehorn, JR | 1 |
| Drummer, OH | 1 |
| Ernst, E | 1 |
| Bartu, A | 1 |
| Popescu, A | 1 |
| Ileutt, KF | 1 |
| Hansson, R | 1 |
| Plumley, N | 1 |
| OULIE, C | 1 |
| NAEVE, W | 1 |
| KORNER, KF | 1 |
| ALHA, AR | 1 |
| OHELA, K | 1 |
| PETERSOHN, F | 1 |
| ZIEHME, E | 1 |
| SCHMIDT, G | 1 |
| Wong, SH | 1 |
| Wagner, MA | 1 |
| Jentzen, JM | 1 |
| Schur, C | 1 |
| Bjerke, J | 1 |
| Gock, SB | 1 |
| Chang, CC | 1 |
| Holly, G | 1 |
| Corkery, JM | 1 |
| Schifano, F | 1 |
| Ghodse, AH | 1 |
| Oyefeso, A | 2 |
| Reith, D | 1 |
| Fountain, J | 1 |
| Tilyard, M | 1 |
| Sachdeva, DK | 1 |
| Stadnyk, JM | 1 |
| Yong, RL | 1 |
| Holmes, DT | 1 |
| Sreenivasan, GM | 1 |
| Chan, GM | 1 |
| Stajic, M | 1 |
| Marker, EK | 1 |
| Hoffman, RS | 1 |
| Nelson, LS | 1 |
| Nisse, P | 1 |
| Cezard, C | 1 |
| Peucelle, D | 1 |
| Mathieu-Nolf, M | 1 |
| Paulozzi, LJ | 1 |
| Ryan, GW | 1 |
| Mégarbane, B | 1 |
| Declèves, X | 1 |
| Bloch, V | 1 |
| Bardin, C | 1 |
| Chast, F | 1 |
| Baud, FJ | 1 |
| Ødegård, E | 1 |
| Amundsen, EJ | 1 |
| Kielland, KB | 1 |
| Fugelstad, A | 1 |
| Stenbacka, M | 1 |
| Leifman, A | 1 |
| Nylander, M | 1 |
| Thiblin, I | 1 |
| González Castro, A | 1 |
| Martín Egaña, M | 1 |
| Suberviola Cañas, B | 1 |
| Teja Barbero, JL | 1 |
| Shields, LB | 1 |
| Hunsaker Iii, JC | 1 |
| Corey, TS | 1 |
| Ward, MK | 1 |
| Stewart, D | 1 |
| Spear, HB | 1 |
| Tenenbein, M | 1 |
| Harding-Pink, D | 1 |
| Worm, K | 1 |
| Steentoft, A | 1 |
| Kringsholm, B | 1 |
| Williamson, PA | 1 |
| Foreman, KJ | 1 |
| White, JM | 1 |
| Anderson, G | 1 |
| Lalkin, A | 1 |
| Kapur, BM | 1 |
| Verjee, ZH | 1 |
| Koren, G | 1 |
| Sporkert, F | 1 |
| Pragst, F | 1 |
| Valmana, A | 1 |
| Clancy, C | 1 |
| Ghodse, H | 1 |
| Stephens, BG | 1 |
| Sembach, N | 1 |
| Levy, A | 1 |
| Masmoudi, R | 1 |
| Edel, Y | 1 |
| Gratien, M | 1 |
| Davido, A | 1 |
| Heinemann, A | 1 |
| Iwersen-Bergmann, S | 1 |
| Stein, S | 1 |
| Schmoldt, A | 1 |
| Püschel, K | 1 |
| Li, L | 1 |
| Levine, B | 1 |
| Smialek, JE | 1 |
| Teisberg, P | 1 |
| Skjoto, J | 1 |
| Lunde, PK | 1 |
| Sesso, AM | 1 |
| Rodzvilla, JP | 1 |
| Nelson, PE | 1 |
| Selkirk, RC | 1 |
| Gayle, MO | 1 |
| Ryan, CA | 1 |
| Nazarali, S | 1 |
| Hickson, GB | 1 |
| Altemeier, WA | 1 |
| Martin, ED | 1 |
| Campbell, PW | 1 |
| Aronow, R | 2 |
| Brenner, SL | 1 |
| Woolley, PV | 2 |
| Seeler, RA | 1 |
| Gardner, R | 1 |
| Azizi, F | 1 |
| Vagenakis, AG | 1 |
| Portnay, GI | 1 |
| Braverman, LE | 1 |
| Ingbar, SH | 1 |
| Hancock, BW | 1 |
| Scherz, RG | 1 |
| Young, DP | 1 |
| Buchner, LH | 1 |
| Cimino, JA | 1 |
| Raybin, HW | 1 |
| Stewart, B | 1 |
| McBay, AJ | 1 |
| Blatman, S | 2 |
| Kersh, ES | 1 |
| Arena, JM | 1 |
| Waldron, VD | 1 |
| Klimt, CR | 1 |
| Seibel, JE | 1 |
| Simons, PS | 1 |
| Lee, KD | 1 |
| Lovejoy, FH | 1 |
| Haddow, JE | 1 |
| Irey, NS | 1 |
| Froede, RC | 1 |
| Robinson, AE | 1 |
| Holder, AT | 1 |
| Hallgrimsson, O | 1 |
| Norheim, G | 1 |
| Sey, MJ | 1 |
| Rubenstein, D | 1 |
| Smith, DS | 1 |
| Paul, SD | 1 |
| Gordon, E | 1 |
| Dimov, D | 1 |
| Beritić, T | 1 |
| Inselman, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Test of a Workforce Development Intervention to Expand Buprenorphine Prescribers[NCT02926482] | 76 participants (Actual) | Interventional | 2016-10-26 | Completed | |||
| PRevention Of Methamphetamine Use Among Postpartum Women Trial (PROMPT)[NCT05128071] | Early Phase 1 | 40 participants (Anticipated) | Interventional | 2022-02-04 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for methadone and Poisoning
| Article | Year |
|---|---|
Antipsychotic-related fatal poisoning, England and Wales, 1993-2013: impact of the withdrawal of thioridazine.
Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Drug Recalls; England; Heroin; Hum | 2016 |
Methadone-related deaths in Western Australia 1993-99.
Topics: Adolescent; Adult; Benzodiazepines; Cause of Death; Drug Interactions; Female; Forensic Medicine; Hu | 2002 |
The effects of methadone and its role in fatalities.
Topics: Cause of Death; Drug Interactions; Drug Overdose; Humans; Metabolic Clearance Rate; Methadone; Narco | 2004 |
Are one or two dangerous? Opioid exposure in toddlers.
Topics: Analgesics, Opioid; Child, Preschool; Codeine; Dose-Response Relationship, Drug; Drug Overdose; Emer | 2005 |
Toxicological findings in fatal poisonings.
Topics: 1-Propanol; Alcoholic Intoxication; Amphetamine; Carbon Monoxide Poisoning; Chloral Hydrate; Chlordi | 1973 |
Narcotic poisoning of children (1) through accidental ingestion of methadone and (2) in utero.
Topics: Administration, Oral; Apgar Score; Birth Weight; Child; Child Care; Female; Gestational Age; Heroin | 1974 |
77 other studies available for methadone and Poisoning
| Article | Year |
|---|---|
Fatalities Due to Poisoning with Aluminum Phosphide (Rice Pill) and Methadone.
Topics: Aluminum Compounds; Humans; Male; Methadone; Oryza; Phosphines; Poisoning | 2022 |
Opioid poisoning in Newcastle over the last three decades: From heroin to prescription opioids.
Topics: Adult; Analgesics, Opioid; Australia; Codeine; Female; Heroin; Humans; Male; Methadone; Naloxone; Ox | 2023 |
Epidemiology of pediatric buprenorphine and methadone exposures reported to the poison centers.
Topics: Buprenorphine; Child; Child, Preschool; Databases, Factual; Environmental Exposure; Female; Humans; | 2020 |
Non-Opioid Substances Acute Poisonings with Suicidal Intent in Patients with Opioid Use Disorder.
Topics: Adolescent; Adult; Analgesics, Opioid; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; | 2020 |
A study of the effectiveness of naltrexone in preventing recurrence of methadone poisoning in opioid-naive children.
Topics: Adolescent; Aftercare; Analgesics, Opioid; Child; Child, Preschool; Female; Hospitalization; Humans; | 2021 |
A possible biomarker for methadone related deaths.
Topics: Adult; Apoptosis; Brain Stem; Caspase 9; Cohort Studies; Female; Forensic Pathology; Forensic Toxico | 2017 |
Electrocardiographic Findings in Mortalities Due to Pure Methadone Toxicity.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Arrhythmias, Cardiac; Cardiotoxicity; Cause of Death; C | 2019 |
Acute adult and adolescent poisoning in Tehran, Iran; the epidemiologic trend between 2006 and 2011.
Topics: Adolescent; Adult; Anticonvulsants; Cross-Sectional Studies; Drug Overdose; Female; Humans; Hypnotic | 2014 |
Drug-poisoning Deaths Involving Opioid Analgesics: United States, 1999-2011.
Topics: Adult; Age Distribution; Analgesics, Opioid; Benzodiazepines; Black or African American; Drug Overdo | 2014 |
Drug-poisoning Deaths Involving Opioid Analgesics: United States, 1999-2011.
Topics: Adult; Age Distribution; Analgesics, Opioid; Benzodiazepines; Black or African American; Drug Overdo | 2014 |
Drug-poisoning Deaths Involving Opioid Analgesics: United States, 1999-2011.
Topics: Adult; Age Distribution; Analgesics, Opioid; Benzodiazepines; Black or African American; Drug Overdo | 2014 |
Drug-poisoning Deaths Involving Opioid Analgesics: United States, 1999-2011.
Topics: Adult; Age Distribution; Analgesics, Opioid; Benzodiazepines; Black or African American; Drug Overdo | 2014 |
Child poisonings with methadone in France: A 6-year prospective national survey since the availability of capsules in 2008.
Topics: Administration, Oral; Adolescent; Age Distribution; Age Factors; Capsules; Child; Child, Preschool; | 2015 |
Deaths by poisoning in Norway 2003-2012.
Topics: Accidents; Analgesics, Opioid; Cause of Death; Heroin; Homicide; Humans; International Classificatio | 2016 |
Severe and fatal pharmaceutical poisoning in young children in the UK.
Topics: Accidents; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Databases, Factual; England; Hos | 2016 |
Retrospective case series analysis of characteristics and trends in unintentional pharmaceutical drug poisoning by methadone, opioid analgesics, antidepressants and benzodiazepines in Clark County, NV 2009-13.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Antidepressive Agents; Benzodiazepin | 2017 |
The underrecognized toll of prescription opioid abuse on young children.
Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Buprenorphine; Child, Preschool; Female | 2009 |
Interindividual variability in the prevalence of OPRM1 and CYP2B6 gene variations may identify drug-susceptible populations.
Topics: Adolescent; Adult; Age Factors; Aryl Hydrocarbon Hydroxylases; Case-Control Studies; Cytochrome P-45 | 2011 |
[Using of reamberin for correction of free radicals disturbances in patients with acute severe methadone poisonings].
Topics: Adult; Female; Free Radicals; Glutathione; Humans; Hypoxia; Lipid Peroxidation; Male; Malondialdehyd | 2012 |
Comparison of fatal poisonings by prescription opioids.
Topics: Accidents; Adolescent; Adult; Analgesics, Opioid; Buprenorphine; Central Nervous System Depressants; | 2012 |
Fatal methadone toxicity: signs and circumstances, and the role of benzodiazepines.
Topics: Adult; Airway Obstruction; Benzodiazepines; Cause of Death; Drug Interactions; Female; Forensic Medi | 2002 |
[Acute methadon poisoning].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Hypnotics and Sedatives; Methadone; Poisoning | 1954 |
[Overdose of methadon causing death in infant].
Topics: Cause of Death; Drug Overdose; Humans; Hypnotics and Sedatives; Infant; Methadone; Poisoning; Respir | 1954 |
Fatal cases of methadone-intoxication in Finland 1951-54, established by forensic-medical examination.
Topics: Finland; Humans; Hypnotics and Sedatives; Methadone; Poisoning | 1955 |
[Case of polamidone poisoning].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Hypnotics and Sedatives; Methadone; Poisoning | 1955 |
[Lorfan, a new morphine antagonist in poisonings in children].
Topics: Child; Humans; Infant; Levallorphan; Methadone; Morphine; Musculoskeletal Physiological Phenomena; P | 1960 |
[Problem of lethal dose and detection of polamidon, with a fatal case of medicinal poisoning].
Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Hypnotics and Sedatives; Methadone; Poisoni | 1955 |
Pharmacogenomics as an aspect of molecular autopsy for forensic pathology/toxicology: does genotyping CYP 2D6 serve as an adjunct for certifying methadone toxicity?
Topics: Adult; Alleles; Case-Control Studies; Cytochrome P-450 CYP2D6; Female; Forensic Medicine; Genetic Ca | 2003 |
Canada: coroner's inquest into the methadone-related death of a prisoner.
Topics: Adult; Female; Forensic Medicine; Humans; Methadone; Poisoning; Prisoners; Saskatchewan | 2004 |
Increase in poisoning deaths caused by non-illicit drugs--Utah, 1991-2003.
Topics: Adult; Aged; Antidepressive Agents; Drug Overdose; Female; Humans; Male; Methadone; Middle Aged; Nar | 2005 |
Opioid poisoning deaths in New Zealand (2001-2002).
Topics: Adolescent; Adult; Aged; Dextropropoxyphene; Drug and Narcotic Control; Drug Prescriptions; Female; | 2005 |
Aluminum toxicity due to intravenous injection of boiled methadone.
Topics: Adult; Aluminum; Ataxia; Chelation Therapy; Deferoxamine; Dysarthria; Humans; Male; Methadone; Poiso | 2006 |
Testing positive for methadone and either a tricyclic antidepressant or a benzodiazepine is associated with an accidental overdose death: analysis of medical examiner data.
Topics: Accidents; Adult; Antidepressive Agents, Tricyclic; Benzodiazepines; Cause of Death; Comorbidity; Co | 2006 |
[Accidental ingestion of methadone and buprenorphine by children. A case review of the Lille Poison Centre between 1995 and 2005].
Topics: Adolescent; Buprenorphine; Child; Child, Preschool; Female; Humans; Infant; Male; Methadone; Narcoti | 2006 |
Opioid analgesics and rates of fatal drug poisoning in the United States.
Topics: Analgesics, Opioid; Humans; Linear Models; Methadone; Oxycodone; Poisoning; Practice Patterns, Physi | 2006 |
Case report: quantification of methadone-induced respiratory depression using toxicokinetic/toxicodynamic relationships.
Topics: Adult; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Infusions, Intravenous; Isomer | 2007 |
Fatal overdoses and deaths by other causes in a cohort of Norwegian drug abusers--a competing risk approach.
Topics: Adult; Age Factors; Amphetamine-Related Disorders; Buprenorphine; Cause of Death; Cohort Studies; Co | 2007 |
Methadone maintenance treatment: the balance between life-saving treatment and fatal poisonings.
Topics: Adult; Female; Heroin Dependence; Humans; Male; Methadone; Narcotics; Poisoning; Risk Factors; Swede | 2007 |
[Pediatric methadone poisoning].
Topics: Child, Preschool; Female; Humans; Infusions, Intravenous; Male; Methadone; Naloxone; Narcotic Antago | 2007 |
Methadone toxicity fatalities: a review of medical examiner cases in a large metropolitan area.
Topics: Adolescent; Adult; Antidepressive Agents; Benzodiazepines; Cannabinoids; Coroners and Medical Examin | 2007 |
Drug abuser deaths.
Topics: Adult; Analgesics, Opioid; Female; Humans; Male; Methadone; Middle Aged; Narcotics; Poisoning; Subst | 1983 |
Continuous naloxone infusion for opiate poisoning in infancy.
Topics: Humans; Infant; Infant, Newborn; Infusions, Parenteral; Male; Meperidine; Methadone; Naloxone; Poiso | 1984 |
Methadone: one person's maintenance dose is another's poison.
Topics: Acquired Immunodeficiency Syndrome; Humans; Methadone; Poisoning; Substance-Related Disorders | 1993 |
Methadone and drug addicts.
Topics: Adolescent; Adult; Alcoholism; Benzodiazepines; Cause of Death; Child; Denmark; Female; Forensic Med | 1993 |
Methadone-related overdose deaths in South Australia, 1984-1994. How safe is methadone prescribing?
Topics: Adult; Australia; Drug Overdose; Drug Prescriptions; Female; Humans; Male; Methadone; Poisoning; Pop | 1997 |
Contamination of antibiotics resulting in severe pediatric methadone poisoning.
Topics: Amoxicillin; Canada; Child, Preschool; Drug Contamination; Humans; Male; Methadone; Narcotics; Penic | 1999 |
Use of headspace solid-phase microextraction (HS-SPME) in hair analysis for organic compounds.
Topics: Antidepressive Agents, Tricyclic; Cannabinoids; Chlormethiazole; Diphenhydramine; Gas Chromatography | 2000 |
Methadone-related deaths: data from 18 coroners' jurisdictions in England.
Topics: Adult; Coroners and Medical Examiners; Drug Prescriptions; England; Female; Humans; Male; Methadone; | 2000 |
Toxicology and pathology of deaths related to methadone: retrospective review.
Topics: Adult; Drug Overdose; Female; Humans; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Disord | 2000 |
[Acute methadone poisoning].
Topics: Acute Disease; Adult; Depressive Disorder; Humans; Male; Methadone; Naloxone; Narcotic Antagonists; | 2000 |
Methadone-related fatalities in Hamburg 1990-1999: implications for quality standards in maintenance treatment?
Topics: Analgesics, Opioid; Cause of Death; Drug and Narcotic Control; Germany; Humans; Methadone; Needs Ass | 2000 |
Fatal methadone poisoning in children: Maryland 1992-1996.
Topics: Accidents, Home; Child, Preschool; Fatal Outcome; Female; Humans; Infant; Male; Maryland; Methadone; | 2000 |
[Letter: Use of naloxone (Narcan) in poisoning by morphine, methadone and dextro propoxyphene].
Topics: Dextropropoxyphene; Humans; Methadone; Morphine; Naloxone; Poisoning; Suicide, Attempted | 1976 |
Naloxone therapy in a seven-month-old with methadone poisoning.
Topics: Humans; Infant; Male; Methadone; Naloxone; Poisoning | 1975 |
The toxicology of twelve cases of death involving methadone: examination of postmortem specimens.
Topics: Adolescent; Adult; Amobarbital; Autopsy; Diazepam; Ethanol; Female; Humans; Male; Methadone; Methaqu | 1975 |
Unusual cause of methadone poisoning.
Topics: Amoxicillin; Drug Compounding; Female; Humans; Infant; Medication Errors; Methadone; Naloxone; Pharm | 1991 |
Parental administration of chemical agents: a cause of apparent life-threatening events.
Topics: Acetaminophen; Apnea; Cyanosis; Female; Humans; Infant; Infant, Newborn; Male; Methadone; Parents; P | 1989 |
An apparent epidemic: methadone poisoning in children.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Ipecac; Male; Methadone; Nalorphine; Po | 1973 |
Accidental ingestion.
Topics: Accidents; Atropine; Chicago; Child; Dextropropoxyphene; Female; Gastric Lavage; Gastrointestinal Ag | 1973 |
Deaths in United Kingdom opioid users 1965-69.
Topics: Alkaloids; Cocaine; Demography; Heroin; Humans; Methadone; Opium; Poisoning; Substance-Related Disor | 1970 |
Thyroxine transport and metabolism in methadone and heroin addicts.
Topics: Adult; Biological Transport; Chronic Disease; Female; Humans; Injections, Intravenous; Male; Methado | 1974 |
Letter: Unsuspected opiate overdose.
Topics: Adolescent; Antidotes; Codeine; Cyclizine; Drug Combinations; Ethers, Cyclic; Female; Humans; Inject | 1974 |
The management of accidental childhood poisoning.
Topics: Accidents, Home; Aspirin; Charcoal; Child; Child, Preschool; Humans; Hydrocarbons; Infant; Methadone | 1974 |
Case study: a modern tragedy.
Topics: Humans; Methadone; Poisoning; Substance-Related Disorders | 1972 |
Naloxone reversal of methadone poisoning.
Topics: Adult; Child, Preschool; Female; Humans; Infant; Male; Methadone; Morphinans; Naloxone; Narcotic Ant | 1972 |
Treatment of propoxyphene overdosage with naloxone.
Topics: Adult; Coma; Dextropropoxyphene; Female; Humans; Infant; Methadone; Naloxone; Poisoning | 1973 |
Two current poisonings: tricyclic drugs and methadone.
Topics: Anti-Arrhythmia Agents; Antidepressive Agents; Barbiturates; Catecholamines; Diuresis; Gastric Lavag | 1973 |
Methadone overdose treated with naloxone infusion.
Topics: Adolescent; Humans; Injections, Intravenous; Male; Methadone; Naloxone; Poisoning | 1973 |
The treatment of methadone poisoning with naloxone (Narcan).
Topics: Female; Humans; Infant; Medication Errors; Methadone; Naloxone; Poisoning | 1973 |
Childhood methadone intoxication.
Topics: Administration, Oral; Boston; Child; Child, Preschool; Drug Packaging; Female; Heroin Dependence; Hu | 1974 |
Evaluation of deaths from drug overdose. A clinicopathologic study.
Topics: Accidents; Adolescent; Adult; Aged; Barbiturates; Child; Chloroquine; Dextropropoxyphene; Female; Gl | 1974 |
Chemical evaluation of 'drug cocktails' in autopsy specimens.
Topics: Adult; Amphetamine; Autopsy; Barbiturates; Body Fluids; Forensic Medicine; Hallucinogens; Humans; Hy | 1974 |
[Letter: Methadone misuse and poisoning].
Topics: Humans; Methadone; Poisoning; Substance-Related Disorders | 1974 |
[Letter: Drug addiction and poisoning with methadone].
Topics: Humans; Methadone; Norway; Poisoning; Substance-Related Disorders | 1974 |
Accidental methadone intoxication in a child.
Topics: Antidotes; Child, Preschool; Humans; Infusions, Parenteral; Male; Methadone; Nalorphine; Oxygen Inha | 1971 |
Childhood poisoning. An unfortunate consequence of methadone availability.
Topics: Child; Child, Preschool; Female; Gastric Lavage; Humans; Infant; Injections, Intravenous; Intubation | 1972 |
Treatment of methadone poisoning.
Topics: Humans; Methadone; Naloxone; Poisoning | 1972 |
[Acute poisoning by methadone (Heptanon)].
Topics: Acute Disease; Child; Humans; Methadone; Poisoning | 1971 |
Methadone and children.
Topics: Adolescent; Adult; Child, Preschool; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Mat | 1971 |
Accidental methadone poisoning.
Topics: Child, Preschool; Humans; Male; Methadone; Poisoning | 1971 |