methadone has been researched along with Obesity in 12 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, pharmacokinetic studies in children with obesity are challenging to conduct, so there is limited information to guide fentanyl and methadone dosing in these children." | 5.72 | Use of physiologically-based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity. ( Al-Uzri, A; Atz, AM; Carreño, FO; Delmore, P; Edginton, AN; Ford, JL; Gerhart, JG; Gonzalez, D; Muller, WJ; Perrin, EM; Watt, KM, 2022) |
| " In light of the ongoing opioid epidemic, the purpose of the current study was to understand the prevalence and health-related correlates of loss of control (LOC) eating in adults seeking methadone maintenance treatment primarily for addiction to heroin and/or painkillers." | 3.88 | Prevalence and Correlates of Loss of Control Eating among Adults Presenting for Methadone Maintenance Treatment. ( Bond, DS; Bryson, WC; Cotton, BP; Goldschmidt, AB; Laurent, J; Mackey, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vallecillo, G | 1 |
| Pedro-Botet, J | 1 |
| Fernandez, S | 1 |
| Román, I | 1 |
| Elosua, R | 1 |
| Camps, A | 1 |
| Torrens, M | 1 |
| Marrugat, J | 1 |
| Gerhart, JG | 1 |
| Carreño, FO | 1 |
| Ford, JL | 1 |
| Edginton, AN | 1 |
| Perrin, EM | 1 |
| Watt, KM | 1 |
| Muller, WJ | 1 |
| Atz, AM | 1 |
| Al-Uzri, A | 1 |
| Delmore, P | 1 |
| Gonzalez, D | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 8 |
| Huang, L | 3 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 4 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 6 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 5 |
| Aleksic Sabo, V | 1 |
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| Borges-Argáez, R | 1 |
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| Sansores-Peraza, P | 1 |
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| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
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| Zhu, J | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care[NCT01431326] | 3,520 participants (Actual) | Observational | 2011-11-30 | Completed | |||
| Effect of Continuous Positive Airway Pressure on Fetal pH at Time of Scheduled Cesarean Delivery in Morbidly Obese Women[NCT04993651] | 80 participants (Anticipated) | Interventional | 2021-10-11 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for methadone and Obesity
1 trial available for methadone and Obesity
10 other studies available for methadone and Obesity
| Article | Year |
|---|---|
High cardiovascular risk in older patients with opioid use disorder: Differences with the general population.
Topics: Aged; Cardiovascular Diseases; Cholesterol; Female; Heart Disease Risk Factors; Humans; Male; Methad | 2022 |
Use of physiologically-based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity.
Topics: Adult; Analgesics, Opioid; Child; Fentanyl; Humans; Methadone; Obesity | 2022 |
Prevalence and Correlates of Loss of Control Eating among Adults Presenting for Methadone Maintenance Treatment.
Topics: Adult; Comorbidity; Eating; Feeding and Eating Disorders; Female; Humans; Male; Methadone; Middle Ag | 2018 |
Additive burdens of malnutrition, poverty, and substance abuse.
Topics: Analgesics, Opioid; Blood Glucose; Cost of Illness; Feeding Behavior; Health Behavior; Health Promot | 2016 |
Nutritional status of deceased illicit drug addicts in Stockholm, Sweden--a longitudinal medicolegal study.
Topics: Adolescent; Adult; Age Distribution; Amphetamine; Body Mass Index; Cannabis; Cocaine; Dopamine Uptak | 2004 |
Impact of spinal anaesthesia and obesity on maternal respiratory function during elective Caesarean section.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Body Mass Index; Cesarean Se | 2004 |
Myocardial Infarction associated with methadone and/or dihydrocodeine.
Topics: Adult; Analgesics, Opioid; Codeine; Humans; Hypercholesterolemia; Male; Methadone; Myocardial Infarc | 2001 |
[Methadone and thyroid disorders].
Topics: Humans; Hypothyroidism; Methadone; Narcotics; Obesity; Opioid-Related Disorders; Weight Gain | 2001 |
Therapeutic self-medication as a context for drug abuse research.
Topics: Adult; Body Weight; Dextroamphetamine; Drug Prescriptions; Female; Fenfluramine; Humans; Male; Metha | 1978 |
Excluded loop syndrome: a complication of jejuno-ileal bypass for obesity.
Topics: Humans; Ileum; Jejunum; Male; Methadone; Middle Aged; Obesity; Postoperative Complications | 1978 |