methadone has been researched along with Nervous System Disorders in 9 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Analgesic effects (lowered maximum pain intensity and increased pain relief, on the day of dosing only) were also seen when the lower daily dose of 10 mg methadone (given as 5 mg bd) was used, but these failed to reach statistical significance (P = 0." | 2.71 | Low-dose methadone has an analgesic effect in neuropathic pain: a double-blind randomized controlled crossover trial. ( Bridson, J; Makin, MK; Miles, JB; Morley, JS; Nash, TP; White, S, 2003) |
| " Narcotics are used for the euphoria they provide; however, chronic use results in physiological and psychological changes." | 2.37 | Narcotic withdrawal in the emergency department. ( Freitas, PM, 1985) |
| "Parenteral substance abuse is widespread." | 1.27 | Primary care of parenteral substance abusers. ( Williams, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carroll, I | 1 |
| Heritier Barras, AC | 1 |
| Dirren, E | 1 |
| Burkhard, PR | 1 |
| Horvath, J | 1 |
| Morley, JS | 1 |
| Bridson, J | 1 |
| Nash, TP | 1 |
| Miles, JB | 1 |
| White, S | 1 |
| Makin, MK | 1 |
| Colvin, L | 1 |
| Forbes, K | 1 |
| Fallon, M | 1 |
| Kreek, MJ | 1 |
| Hartman, N | 1 |
| Dinges, DF | 1 |
| Davis, MM | 1 |
| Glass, P | 1 |
| Selwyn, PA | 1 |
| Iezza, A | 1 |
| Williams, A | 1 |
| Freitas, PM | 1 |
| Thornton, WE | 1 |
| Thornton, BP | 1 |
2 reviews available for methadone and Nervous System Disorders
| Article | Year |
|---|---|
Difficult pain.
Topics: Acupuncture; Analgesia; Analgesics, Opioid; Forecasting; Humans; Methadone; Nervous System Diseases; | 2006 |
Narcotic withdrawal in the emergency department.
Topics: Clonidine; Emergency Service, Hospital; Endorphins; Humans; Methadone; Narcotics; Nervous System Dis | 1985 |
1 trial available for methadone and Nervous System Disorders
| Article | Year |
|---|---|
Low-dose methadone has an analgesic effect in neuropathic pain: a double-blind randomized controlled crossover trial.
Topics: Adult; Aged; Analgesics, Opioid; Confidence Intervals; Cross-Over Studies; Double-Blind Method; Drug | 2003 |
6 other studies available for methadone and Nervous System Disorders
| Article | Year |
|---|---|
Delayed leukoencephalopathy after alprazolam and methadone overdose: a case report and review of the literature.
Topics: Adult; Alprazolam; Analgesics, Opioid; Behavior; Brain; Drug Overdose; Female; Glasgow Coma Scale; H | 2012 |
Chronic use of opioids and antipsychotic drugs: side effects, effects on endogenous opioids, and toxicity.
Topics: Adolescent; Adult; Animals; Antipsychotic Agents; Blood Proteins; Endorphins; Female; Humans; Liver | 1982 |
Fetal exposure to narcotics: neonatal sleep as a measure of nervous system disturbance.
Topics: Birth Weight; Female; Heroin; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; | 1980 |
Zidovudine overdose in an intravenous drug user.
Topics: Adult; Female; HIV Seropositivity; Humans; Methadone; Nervous System Diseases; Substance Abuse, Intr | 1990 |
Primary care of parenteral substance abusers.
Topics: Acquired Immunodeficiency Syndrome; Administration, Intranasal; Antibodies, Viral; Body Weight; Coca | 1986 |
Adverse reactions to heroin use.
Topics: Abscess; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Chromosomes; Endocarditis; Femal | 1974 |