methadone has been researched along with Muscle Rigidity in 3 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report here the case of an infant who developed life-threatening rigid-chest syndrome after receiving an accidental overdose of methadone." | 7.76 | Methadone-induced rigid-chest syndrome after substantial overdose. ( Hack, RA; Lynch, RE, 2010) |
| "We report here the case of an infant who developed life-threatening rigid-chest syndrome after receiving an accidental overdose of methadone." | 3.76 | Methadone-induced rigid-chest syndrome after substantial overdose. ( Hack, RA; Lynch, RE, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lynch, RE | 1 |
| Hack, RA | 1 |
| Barnett, A | 1 |
| Goldstein, J | 1 |
| Fiedler, E | 1 |
| Taber, R | 1 |
| Ahtee, L | 1 |
| Kääriäinen, I | 1 |
| Paasonen, MK | 1 |
3 other studies available for methadone and Muscle Rigidity
| Article | Year |
|---|---|
Methadone-induced rigid-chest syndrome after substantial overdose.
Topics: Drug Administration Schedule; Drug Overdose; Fentanyl; Follow-Up Studies; Humans; Infant, Newborn; I | 2010 |
Etonitazine-induced rigidity and its antagonism by centrally acting muscle relaxants.
Topics: Analgesics, Opioid; Animals; Benzimidazoles; Benzyl Compounds; Catalepsy; Codeine; Cordotomy; Diethy | 1975 |
Effect of nalorphine and antiparkinsonian drugs on methadone-induced rigidity; relation to homovanillic acid content of nucleus caudatus.
Topics: Amantadine; Animals; Atropine; Body Temperature; Brain; Caudate Nucleus; Depression, Chemical; Dose- | 1972 |