Page last updated: 2024-10-30

methadone and Morphine Abuse

methadone has been researched along with Morphine Abuse in 252 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Research Excerpts

ExcerptRelevanceReference
" Thus, the present study aimed to investigate whether the damaging effects of morphine dependence were reversed by the spontaneous morphine withdrawal or incubation with methadone and/or naloxone in Sertoli (TM4) cells using an in- vitro cell model of morphine dependence."8.02Morphine dependence and withdrawal-induced changes in mouse Sertoli cell (TM4) line: Evaluation of apoptotic, inflammatory and oxidative stress biomarkers. ( Miladi-Gorji, H; Pourhassanali, N; Zarbakhsh, S, 2021)
"This study was designed to examine whether treadmill exercise would attenuate the severity of physical dependence, methadone-induced anxiety, depression and voluntary morphine consumption in morphine withdrawn rats receiving methadone maintenance treatment (MMT)."7.88Treadmill exercise attenuates the severity of physical dependence, anxiety, depressive-like behavior and voluntary morphine consumption in morphine withdrawn rats receiving methadone maintenance treatment. ( Alizadeh, M; Miladi-Gorji, H; Zahedi-Khorasani, M, 2018)
" Opioid agonist doses for oxycodone and morphine dependence: Findings from a retrospective case series Drug Alcohol Rev 2017;36:311-316]."7.85Opioid agonist doses for oxycodone and morphine dependence: Findings from a retrospective case series. ( Bruno, R; Degenhardt, L; Demirkol, A; Lintzeris, N; Nielsen, S, 2017)
"Methadone was used subcutaneously as an analgesic agent in 1 patient."6.47Review of cancer pain management in patients receiving maintenance methadone therapy. ( McLean, S; McQuillan, R; O'Gorman, A; Rowley, D; Ryan, K, 2011)
"We orally induced morphine dependence in NMRI male mice, and then performed detoxification programs using either methadone or buprenorphine."4.31Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction. ( Abedini, M; Amirinejad, M; Haghpanah, T; Moinaddini, F; Nematollahi-Mahani, SN; Yoosefi, F, 2023)
" Thus, the present study aimed to investigate whether the damaging effects of morphine dependence were reversed by the spontaneous morphine withdrawal or incubation with methadone and/or naloxone in Sertoli (TM4) cells using an in- vitro cell model of morphine dependence."4.02Morphine dependence and withdrawal-induced changes in mouse Sertoli cell (TM4) line: Evaluation of apoptotic, inflammatory and oxidative stress biomarkers. ( Miladi-Gorji, H; Pourhassanali, N; Zarbakhsh, S, 2021)
"This study was designed to examine whether treadmill exercise would attenuate the severity of physical dependence, methadone-induced anxiety, depression and voluntary morphine consumption in morphine withdrawn rats receiving methadone maintenance treatment (MMT)."3.88Treadmill exercise attenuates the severity of physical dependence, anxiety, depressive-like behavior and voluntary morphine consumption in morphine withdrawn rats receiving methadone maintenance treatment. ( Alizadeh, M; Miladi-Gorji, H; Zahedi-Khorasani, M, 2018)
" Opioid agonist doses for oxycodone and morphine dependence: Findings from a retrospective case series Drug Alcohol Rev 2017;36:311-316]."3.85Opioid agonist doses for oxycodone and morphine dependence: Findings from a retrospective case series. ( Bruno, R; Degenhardt, L; Demirkol, A; Lintzeris, N; Nielsen, S, 2017)
"Nepeta menthoides, similar to methadone, significantly prevented the development (but not the expression) of morphine dependence, tolerance, and potentiated morphine antinociception and also reduced (23."3.85Prevention of morphine dependence and tolerance by Nepeta menthoides was accompanied by attenuation of Nitric oxide overproduction in male mice. ( Beik, A; Rahmati, B, 2017)
"Comprehensive cerebral metabolites involved in morphine dependence have not been well explored."3.78(1) H-nuclear magnetic resonance-based metabonomic analysis of brain in rhesus monkeys with morphine treatment and withdrawal intervention. ( Bu, Q; Cen, X; Deng, P; Deng, Y; Duan, J; Hu, C; Hu, Z; Li, Y; Shao, X; Yan, G; Zhao, J; Zhao, Y; Zhou, J; Zhu, R, 2012)
" Compared to patients with pre-existing heroin, codeine, or morphine abuse respectively, patients from the methadone maintenance programme had significantly higher (P<0."3.70Safety, efficacy, and long-term results of a modified version of rapid opiate detoxification under general anaesthesia: a prospective study in methadone, heroin, codeine and morphine addicts. ( Hensel, M; Kox, WJ, 2000)
"Antipyrine half-life was significantly reduced (12."2.69Effect of fusidic acid on the hepatic cytochrome P450 enzyme system. ( Barthel, B; Brockmeyer, NH; Reimann, G; Rockstroh, JK; Spatz, D, 1999)
"Methadone was used subcutaneously as an analgesic agent in 1 patient."2.47Review of cancer pain management in patients receiving maintenance methadone therapy. ( McLean, S; McQuillan, R; O'Gorman, A; Rowley, D; Ryan, K, 2011)
" This article reviews the World Health Organization recommendations for analgesic therapy in this setting, as well as guidelines for opioid therapy in patients with renal failure or hepatic failure, assessment of pain, dosing strategies in both acute and chronic pain, management of opioid overdose, pain associated with dose-limiting side effects, and pain in the actively dying."2.44Practical guide to opioids and their complications in managing cancer pain. What oncologists need to know. ( Davis, MP; Gamier, P; Lasheen, W, 2007)
"Unfortunately, treatment of opioid dependence is difficult, particularly because of codependence - for example, on alcohol or other drugs of abuse."1.48Disulfiram attenuates morphine or methadone withdrawal syndrome in mice. ( Bujalska-Zadrożny, M; de Cordé, A; Filip, M; Kleczkowska, P; Krząścik, P; Wolińska, R, 2018)
"Methadone maintenance treatment (MMT) is the major tapering therapy for morphine addictive patients."1.46Reduced dosing and liability in methadone maintenance treatment by targeting oestrogen signal for morphine addiction. ( Chen, SH; Chiang, YC; Ho, IK; Ho, WJ; Huang, CL; Lane, HY; Ma, WL; Wang, RY; Yang, HT, 2017)
"Recent clinical studies suggest that substance use may be associated with an acceleration of the ageing process, possibly related to a deficit of stem cell number or function."1.35An intriguing association between dental and mental pathology in addicted and control subjects: a cross-sectional survey. ( Reece, AS, 2008)
"Although it is said that drug addiction is associated with poor dental health, there is little research in this area."1.34Dentition of addiction in Queensland: poor dental status and major contributing drugs. ( Reece, AS, 2007)
"Long-term opioid dependence seems to decrease prefrontal CBF in particular."1.31Opioid addiction changes cerebral blood flow symmetry. ( Brücke, T; Fischer, G; Jagsch, R; Kasper, S; Pezawas, L; Podreka, I; Schindler, S; Thurnher, M, 2002)
"Methadone dosing was flexible, with patient participation in dose decisions."1.30The relationship of methadone dose and other variables to outcomes of methadone maintenance. ( Maddux, JF; Prihoda, TJ; Vogtsberger, KN, 1997)
"Methadone alone was found to be the cause of death in 50% more cases in 1989 than in 1981."1.29Methadone and drug addicts. ( Kringsholm, B; Steentoft, A; Worm, K, 1993)
"4 mg/ml for morphine and methadone, respectively, were achieved using an ascending dosage schedule."1.28Morphine and methadone dependence in the rat: withdrawal and brain met-enkephalin levels. ( Olley, JE; Pierce, TL; Tiong, GK, 1992)
"Methadone-treated subjects show a similar effect at phagocytic level but far less evident."1.27Morphine and methadone impact on human phagocytic physiology. ( Avico, U; Borelli, G; Cavallo, G; Croce, C; Pacifici, R; Santiangeli, C; Tubaro, E; Zuccaro, P, 1985)
"Methadone was shown to partially block the decrease in diet intake and the weight loss seen during morphine withdrawal."1.27Aspects of abstinence after morphine ingestion. ( Eriksson, PS; Rönnbäck, L; Rosengren, L; Wronski, A; Zeuchner, J, 1987)
"Thrombocytosis was not related to withdrawal symptoms or treatment (phenobarbital or paregoric)."1.26Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users. ( Burstein, Y; Giardina, PJ; Kandall, SR; Peterson, CM; Rausen, AR; Siljestrom, K, 1979)

Research

Studies (252)

TimeframeStudies, this research(%)All Research%
pre-1990215 (85.32)18.7374
1990's8 (3.17)18.2507
2000's12 (4.76)29.6817
2010's15 (5.95)24.3611
2020's2 (0.79)2.80

Authors

AuthorsStudies
Pourhassanali, N1
Zarbakhsh, S1
Miladi-Gorji, H3
Moinaddini, F3
Amirinejad, M3
Haghpanah, T3
Abedini, M3
Yoosefi, F3
Nematollahi-Mahani, SN3
Santoro, GC1
Carrion, J1
Patel, K1
Vilchez, C1
Veith, J1
Brodie, JD1
Dewey, SL1
Chiang, YC3
Wang, RY1
Huang, CL1
Chen, SH1
Ho, WJ1
Lane, HY1
Ho, IK3
Yang, HT1
Ma, WL1
de Cordé, A1
Krząścik, P1
Wolińska, R1
Kleczkowska, P1
Filip, M1
Bujalska-Zadrożny, M1
Alizadeh, M2
Zahedi-Khorasani, M2
Bandegi, AR1
Yousefi, B1
Rashidy-Pour, A1
Sameni, HR1
Zamani, N1
Hassanian-Moghaddam, H1
Bayat, AH1
Haghparast, A1
Shadnia, S1
Rahimi, M1
Hashemi Demaneh, B1
Assar, N1
Ye, LC1
Hsu, KY1
Liao, CW1
Hung, TW2
Lo, WJ1
Tao, PL1
Christoffersen, DJ1
Damkier, P1
Feddersen, S1
Möller, S1
Thomsen, JL1
Brasch-Andersen, C1
Brøsen, K1
Nielsen, S1
Bruno, R1
Degenhardt, L1
Demirkol, A1
Lintzeris, N1
Rahmati, B1
Beik, A1
Reece, AS2
Pedersen, CL1
Steentoft, A2
Kringsholm, B2
Lee, CW1
Yan, JY1
Raehal, KM1
Bohn, LM1
Rowley, D1
McLean, S1
O'Gorman, A1
Ryan, K1
McQuillan, R1
Deng, Y1
Bu, Q1
Hu, Z1
Deng, P1
Yan, G1
Duan, J1
Hu, C1
Zhou, J1
Shao, X1
Zhao, J1
Li, Y1
Zhu, R1
Zhao, Y1
Cen, X1
Tschacher, W1
Haemmig, R1
Jacobshagen, N1
ISBELL, H3
WHITE, WM1
WIKLER, A1
RAYPORT, M1
FAUCETT, RL2
SCHRAPPE, O1
BURCHARD, JM2
GEHLKEN, K1
MEYERSTEIN, AN1
WEEKS, JR2
HAMBURGER, E1
ROSENTHAL, T1
PATRICK, SW1
KRUG, DC1
COLLINS, RJ1
Tuffs, A1
He, L1
Whistler, JL1
Novick, DM1
Kreek, MJ3
Davis, MP1
Lasheen, W1
Gamier, P1
VOGEL, VH1
Nyswander, M1
Dole, VP7
Pandey, GN1
DeLeon-Jones, FA1
Inwang, EE1
Davis, JM1
Haastrup, S1
Jepsen, PW1
Olofsson, M1
Buckley, W1
Andersen, GE1
Friis-Hansen, B1
Scordato, M1
Masten, LW3
Peterson, GR2
Burkhalter, A1
Way, EL3
Steinfels, GF3
Young, GA5
Khazan, N6
Jasinski, DR2
Cushman, P3
Haertzen, CA1
Ross, FE1
Dugarin, J2
Menerath, C1
Nominé, P1
Kaa, E1
Teige, B1
Worm, K1
Maddux, JF4
Prihoda, TJ1
Vogtsberger, KN1
Reimann, G1
Barthel, B1
Rockstroh, JK1
Spatz, D1
Brockmeyer, NH1
Grünberger, J1
Linzmayer, L1
Fischer, G2
Pezawas, L2
Stöhr, H1
Grünberger, M1
Hensel, M1
Kox, WJ1
Kolarzyk, E1
Targosz, D1
Pach, D1
Misiołek, L1
Podreka, I1
Schindler, S1
Brücke, T1
Jagsch, R1
Thurnher, M1
Kasper, S1
Sollod, RM1
Goldstein, MG1
Berkowitz, BA1
Ladewig, D1
Senay, EC1
Harvey, WH1
Oss, JN1
Turk, RF1
Ginther, ME1
Rubenstein, RB1
Spira, I1
Wolff, WI1
Stimmel, B1
Glick, SD1
Fraser, HF2
Kay, DC3
Yeh, SY1
Gorodetzky, CW1
Dewey, WL1
Riley, AL1
Etherton, DS1
Shapiro, RM1
Moreton, JE3
Meltzer, LT1
Pickworth, WB1
Neidert, GL1
Falcone, D1
Fishman, PM1
Othmer, E1
Chiba, S1
Burstein, Y1
Giardina, PJ1
Rausen, AR1
Kandall, SR1
Siljestrom, K1
Peterson, CM1
Bartoloni Saint Omer, F1
Montalto, B1
Chibaro, G1
Manfredini, F1
Werner, TE2
Smith, SG2
Davis, WM2
Covault, HP1
Hostetler, RM1
Huidobro, F1
Hine, CH1
Babbini, M2
Gaiardi, M2
Bartoletti, M2
Anggård, E2
Grönbladh, L1
Holmstrand, J2
Westermeyer, J2
Roehrs, T1
Killam, KF1
Brocco, MJ1
Robinson, CA1
Glazer, WM1
Cohn, GL1
Knipschildt, HE1
Gossop, MR1
Roy, A1
Bishop, BP1
Cave, GC1
Gay, MJ1
Morgan, HG1
Jacob, RG1
Eriksson, JH1
Byers, JM1
Soin, JS1
Fisher, RS1
Hutchins, GM1
Halbach, H2
Iorio, LC1
Deacon, MA1
Ryan, EA1
Cox, BM1
Ginsburg, M1
Willis, J1
Henwood, RW1
Mazurikiewicz-Kwilecki, IM1
Leander, JD1
McMillan, DE1
Harris, LS1
Hine, B1
Torrelio, M1
Gershon, S1
Silverstone, PH1
Attenburrow, MJ1
Robson, P1
Pierce, TL1
Tiong, GK1
Olley, JE1
Bronson, ME1
Sparber, SB1
Babaian, EA1
Bulaev, VM1
Tubaro, E1
Avico, U1
Santiangeli, C1
Zuccaro, P1
Cavallo, G1
Pacifici, R1
Croce, C1
Borelli, G1
Contreras, E1
Fernández, E1
Villar, M1
Dougherty, PM1
Pearl, J1
Krajewski, KJ1
Pellis, NR1
Dafny, N1
Rönnbäck, L1
Eriksson, PS1
Zeuchner, J1
Rosengren, L1
Wronski, A1
Gubellini, C1
Bacchi, A1
Eddy, NB1
May, EL1
Kreuzer, A1
Singhal, RL2
Kacew, S1
Lafreniere, R1
Schönhöfer, PS1
Hasse, HE1
Maruyama, Y1
Hayashi, G1
Smits, SE1
Takemori, AE2
Davison, K1
Osselton, JW1
Vaille, C1
Weissman, S1
Stesin, AJ1
Tulunay, FC1
Silsby, H1
Tennant, FS1
Fournier, E1
Gorceix, A1
Bourdon, P1
Piva, C1
Deniker, P1
Lôo, H1
Zarifian, E1
Cuche, H1
Teiger, DG1
Fram, DH1
Hoffman, HA1
Jhamandas, K1
Dickinson, G1
Kaneto, H2
Koida, M2
Nakanishi, H2
Sasano, H1
Wilson, CW1
DeBoer, L1
Riedesser, P1
Muuss, RE1
Goldstein, A1
Taylor, WJ1
Chambers, CD4
Bowling, CE1
Walters, I1
Fernandes, M1
Bowden, CL2
Maslansky, RA2
Jensen, GR1
Meyer, A1
Lissac, J1
Rochemaure, J1
Garbarg, S1
Lebeau, B1
Puri, S1
Lal, H1
Nutt, JG1
Parker, RR1
Cobb, JP1
Connell, PH1
Kerr, FW1
Triplett, JN1
Beeler, GW1
Merali, Z1
Ghosh, PK1
Hrdina, PD1
Ling, GM1
Zaks, AM1
Bruner, A1
Fink, M3
Freedman, AM3
Robinson, JW1
Orraca, J1
Towns, E1
Searcy, P1
Caine, E1
Jaffe, JH5
Schuster, CR3
Smith, BB2
Blachley, PH1
Langrod, J2
Dupont, RL1
O'Malley, JE1
Anderson, WH1
Lazare, A1
Levy, BS1
Baker, SL1
Levin, G1
Hirsch, G1
Roberts, E1
Sloboda, SB1
Cassidy, WJ1
Lesse, S1
Richman, A2
Perkins, ME4
Bihari, B1
Fishman, JJ1
Renault, PF1
Poze, RS1
Sheppard, CW1
Smith, DE1
Gay, GR1
Glatt, M1
Robbins, PR1
Cary, W1
Hussain, MZ1
Harinath, M1
Logan, DG1
Sullivan, RD1
Fischbach, AL1
Hornick, FW1
Paris, MD1
Kumar, R1
Stolerman, IP1
Erikson, JH1
Weppner, RS1
Stephens, RC1
Conrad, HT1
Levine, DG1
Levin, DB1
Sloan, IH1
Chappel, JN1
Falek, A1
Jordan, RB1
King, BJ1
Arnold, PJ1
Skelton, WD1
Montalvo, JG1
Scrignar, CB1
Alderette, E1
Harper, B1
Eyer, D1
Annunziato, D1
Warner, A2
Davis, EP2
Hughes, PH1
Crawford, GA1
Barker, NW1
Schumann, S1
Meester, WD1
Maternowski, CJ1
Millard, JA1
Jones, EA1
Huisman, HB1
Kooistra, WH1
Philips, DF1
Borenstein, D1
Blinick, G1
Faller, W1
Berkelhamer, JE1
Esterly, JR1
James, IP1
Hawks, DV1
Fritz, K1
Kaistha, KK1
Morton, FL1
Pearson, BA1
Kromberg, CJ1
Proctor, JB1
McDermott, R1
Krome, RL1
Billingslea, S1
Koenig, RK1
Hand, MK1
Nyswander, ME2
Pool, JL1
Crawley, JA1
Marshall, I1
Weinstock, M1
Blachly, PH1
Bloch, HI1
Lorenzetti, OJ1
Sancilio, LF1
Nix, JT1
Hoffman, L1
Torrens, PR1
Trussell, RE3
Gollance, H1
Maslansky, R1
Knowles, R1
Lahiri, S1
Anderson, G1
Wieland, WF3
Williams, HR2
Kleber, HD1
Bloom, WA1
Sudderth, EW1
Baden, MM1
Hoogerbeets, J1
Zaks, A2
Resnick, R1
Gearing, FR1
Martin, WR1
Moy, W1
Johnston, W1
Saunders, JW1
Wolfson, EA1
Retterstol, N1
Treuting, JJ1
Resnick, RB1
Elliott, HW1
Noble, P1
Barnes, GG1
Akera, T1
Brody, TM1
Patch, VD1
Gunne, LM1

Reviews

13 reviews available for methadone and Morphine Abuse

ArticleYear
Review of cancer pain management in patients receiving maintenance methadone therapy.
    The American journal of hospice & palliative care, 2011, Volume: 28, Issue:3

    Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Huma

2011
DRUG ADDICTION: A REVIEW.
    The Journal of school health, 1964, Volume: 34

    Topics: Adolescent; Amphetamine; Amphetamines; Barbiturates; Cannabis; Codeine; Heroin; Humans; Hydromorphon

1964
Practical guide to opioids and their complications in managing cancer pain. What oncologists need to know.
    Oncology (Williston Park, N.Y.), 2007, Volume: 21, Issue:10

    Topics: Analgesics, Opioid; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Routes; D

2007
Biological correlates of methadone maintenance pharmacotherapy.
    Annales de medecine interne, 1994, Volume: 145 Suppl 3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Chromatography, Gas; Cocaine; Heroin Dependence; Humans;

1994
Rx: 3x/week LAAM: alternative to methadone. Clinical studies: Phase I.
    NIDA research monograph, 1976, Issue:8

    Topics: Analgesics; Analgesics, Opioid; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluat

1976
The relationship of pharmacokinetics to pharmacological activity: morphine, methadone and naloxone.
    Clinical pharmacokinetics, 1976, Volume: 1, Issue:3

    Topics: Absorption; Aging; Aspirin; Blood Proteins; Dose-Response Relationship, Drug; Drug Interactions; Fem

1976
[The treatment of drug-dependence (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1978, Jun-27, Volume: 67, Issue:26

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Alcoholism; Amphetamines; Barbiturates; Communicatio

1978
Possible effects of normetabolites on the subjective and reinforcing characteristics of opioids in animals and man.
    Drug and alcohol dependence, 1978, Volume: 3, Issue:5

    Topics: Animals; Dealkylation; Dextropropoxyphene; Dogs; Haplorhini; Heroin Dependence; Humans; Methadone; M

1978
[Pharmacologic aspects of the treatment of drug addiction due to morphine-like substances].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1989, Volume: 89, Issue:1

    Topics: Anti-Anxiety Agents; Benzodiazepines; Heroin Dependence; Humans; Methadone; Morphine Dependence; Nar

1989
Advances in the treatment of drug addiction.
    The Practitioner, 1972, Volume: 209, Issue:252

    Topics: Alcoholism; Amphetamine; Aversive Therapy; Barbiturates; Heroin; Humans; Lysergic Acid Diethylamide;

1972
[Management of opium addicts using opiates and their antagonists].
    Der Nervenarzt, 1972, Volume: 43, Issue:10

    Topics: Crime; Cyclazocine; Economics; Germany, West; Heroin; Humans; Methadone; Morphine Dependence; Naloxo

1972
The opiates and their derivatives.
    Texas medicine, 1973, Volume: 69, Issue:6

    Topics: Codeine; Dose-Response Relationship, Drug; Drug Tolerance; Hallucinogens; Humans; Methadone; Morphin

1973
[Methadone program in the USA. Experience and problems].
    Medizinische Klinik, 1974, Apr-19, Volume: 69, Issue:16

    Topics: Chemical Phenomena; Chemistry; Evaluation Studies as Topic; Germany, West; Heroin Dependence; Humans

1974

Trials

11 trials available for methadone and Morphine Abuse

ArticleYear
Time series modeling of heroin and morphine drug action.
    Psychopharmacology, 2003, Volume: 165, Issue:2

    Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Int

2003
Effect of fusidic acid on the hepatic cytochrome P450 enzyme system.
    International journal of clinical pharmacology and therapeutics, 1999, Volume: 37, Issue:11

    Topics: Anti-Bacterial Agents; Antipyrine; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Sys

1999
Rx: 3x/week LAAM: alternative to methadone. Clinical studies: Phase I.
    NIDA research monograph, 1976, Issue:8

    Topics: Analgesics; Analgesics, Opioid; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluat

1976
Opioid effects on computer-derived sleep and EEG parameters in nondependent human addicts.
    Sleep, 1979, Volume: 2, Issue:2

    Topics: Adult; Arousal; Computers; Dose-Response Relationship, Drug; Electroencephalography; Heroin Dependen

1979
Propranolol in the treatment of opiate dependence -- a controlled study.
    Psychopharmacologia, 1975, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Clinical Trials as Topic; Euphoria; Female; Heart Rate; Humans; Male; Methadone;

1975
The calcium channel antagonist nifedipine causes confusion when used to treat opiate withdrawal in morphine-dependent patients.
    International clinical psychopharmacology, 1992, Volume: 7, Issue:2

    Topics: Adult; Clonidine; Confusion; Double-Blind Method; Humans; Male; Methadone; Morphine Dependence; Nife

1992
Studies on the relationship between 5-hydroxytryptamine turnover in brain and tolerance and physical dependence in mice.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 178, Issue:1

    Topics: Animals; Aspirin; Brain; Cyclazocine; Drug Tolerance; Fenclonine; Humans; Levorphanol; Male; Methado

1971
Intravenous diacetylmorphine (heroin) in studies of opiate dependence.
    Diseases of the nervous system, 1969, Volume: 30, Issue:2

    Topics: Bridged-Ring Compounds; Clinical Trials as Topic; Cyclazocine; Electroencephalography; Frontal Lobe;

1969
Methadone treatment of randomly selected criminal addicts.
    The New England journal of medicine, 1969, Jun-19, Volume: 280, Issue:25

    Topics: Adolescent; Adult; Black or African American; Clinical Trials as Topic; Crime; Educational Status; E

1969
Comparison of acetylmethadol and methadone in the treatment of long-term heroin users. A pilot study.
    JAMA, 1970, Mar-16, Volume: 211, Issue:11

    Topics: Alcohols; Clinical Trials as Topic; Heroin; Humans; Methadone; Morphine Dependence; Placebos; Substa

1970
Drug abuse in heroin users. An experimental study of self-administration of methadone, codeine, and pentazocine.
    Archives of general psychiatry, 1971, Volume: 24, Issue:4

    Topics: Administration, Oral; Clinical Trials as Topic; Codeine; Heroin; Humans; Methadone; Morphine Depende

1971

Other Studies

229 other studies available for methadone and Morphine Abuse

ArticleYear
Morphine dependence and withdrawal-induced changes in mouse Sertoli cell (TM4) line: Evaluation of apoptotic, inflammatory and oxidative stress biomarkers.
    Reproductive toxicology (Elmsford, N.Y.), 2021, Volume: 105

    Topics: Analgesics, Opioid; Animals; Apoptosis; Biomarkers; Cell Line; Cyclic AMP; Glial Cell Line-Derived N

2021
Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Chromatin; Male; Methadone; Mice; Morphine; Morphine Dep

2023
Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Chromatin; Male; Methadone; Mice; Morphine; Morphine Dep

2023
Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Chromatin; Male; Methadone; Mice; Morphine; Morphine Dep

2023
Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Chromatin; Male; Methadone; Mice; Morphine; Morphine Dep

2023
Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Chromatin; Male; Methadone; Mice; Morphine; Morphine Dep

2023
Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Chromatin; Male; Methadone; Mice; Morphine; Morphine Dep

2023
Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Chromatin; Male; Methadone; Mice; Morphine; Morphine Dep

2023
Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Chromatin; Male; Methadone; Mice; Morphine; Morphine Dep

2023
Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Chromatin; Male; Methadone; Mice; Morphine; Morphine Dep

2023
Sex Differences in Regional Brain Glucose Metabolism Following Opioid Withdrawal and Replacement.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:9

    Topics: Analgesics, Opioid; Animals; Brain; Brain Mapping; Buprenorphine; Cross-Sectional Studies; Disease M

2017
Reduced dosing and liability in methadone maintenance treatment by targeting oestrogen signal for morphine addiction.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:12

    Topics: Adult; Animals; Cytochrome P-450 CYP2B6; Estradiol; Estrogen Antagonists; Female; Gene Expression Re

2017
Disulfiram attenuates morphine or methadone withdrawal syndrome in mice.
    Behavioural pharmacology, 2018, Volume: 29, Issue:5

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Disulfiram; Male; Methadone; Mice; Mice, Inbred C57BL

2018
Treadmill exercise attenuates the severity of physical dependence, anxiety, depressive-like behavior and voluntary morphine consumption in morphine withdrawn rats receiving methadone maintenance treatment.
    Neuroscience letters, 2018, 08-10, Volume: 681

    Topics: Animals; Anxiety; Depression; Exercise Test; Male; Maze Learning; Methadone; Morphine; Morphine Depe

2018
Effects of treadmill exercise on methadone withdrawal-induced locomotor sensitization and the ventral pallidum and ventral tegmental area BDNF levels in morphine withdrawn rats receiving methadone maintenance treatment.
    Neuroscience letters, 2018, 09-14, Volume: 683

    Topics: Analgesics, Opioid; Animals; Basal Forebrain; Brain-Derived Neurotrophic Factor; Exercise Test; Loco

2018
The lethal burden of drug overdose.
    Lancet (London, England), 2013, Sep-07, Volume: 382, Issue:9895

    Topics: Cause of Death; Cost Control; Cross-Cultural Comparison; Drug Overdose; Heroin Dependence; Humans; I

2013
Reversal of opioid overdose syndrome in morphine-dependent rats using buprenorphine.
    Toxicology letters, 2015, Feb-03, Volume: 232, Issue:3

    Topics: Animals; Buprenorphine; Drug Overdose; Male; Methadone; Morphine Dependence; Naloxone; Narcotic Anta

2015
Beneficial effects of co-treatment with dextromethorphan on prenatally methadone-exposed offspring.
    Journal of biomedical science, 2015, Mar-20, Volume: 22

    Topics: Animals; Antitussive Agents; Dextromethorphan; Female; Male; Methadone; Morphine Dependence; Narcoti

2015
The ABCB1, rs9282564, AG and TT Genotypes and the COMT, rs4680, AA Genotype are Less Frequent in Deceased Patients with Opioid Addiction than in Living Patients with Opioid Addiction.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:4

    Topics: Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B; Catechol O-Methyltransferase

2016
Opioid agonist doses for oxycodone and morphine dependence: Findings from a retrospective case series.
    Drug and alcohol review, 2017, Volume: 36, Issue:3

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Dose-Response Relationship, Drug; Female; Humans; Male; Me

2017
Prevention of morphine dependence and tolerance by Nepeta menthoides was accompanied by attenuation of Nitric oxide overproduction in male mice.
    Journal of ethnopharmacology, 2017, Mar-06, Volume: 199

    Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Male; Methadone; Mice; Morphine Dependenc

2017
An intriguing association between dental and mental pathology in addicted and control subjects: a cross-sectional survey.
    British dental journal, 2008, Dec-13, Volume: 205, Issue:11

    Topics: Adolescent; Adult; Aggression; Aging; Alcohol Drinking; Amphetamine-Related Disorders; Anxiety; Atte

2008
[Deaths among drug addicts in Eastern Denmark 2005].
    Ugeskrift for laeger, 2008, Dec-08, Volume: 170, Issue:50

    Topics: Adult; Cause of Death; Denmark; Drug Overdose; Female; Forensic Toxicology; Heroin Dependence; Human

2008
Enhancement of tolerance development to morphine in rats prenatally exposed to morphine, methadone, and buprenorphine.
    Journal of biomedical science, 2010, Jun-07, Volume: 17

    Topics: Analgesics; Animals; Buprenorphine; Disease Models, Animal; Drug Tolerance; Female; Heroin Dependenc

2010
The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.
    Neuropharmacology, 2011, Volume: 60, Issue:1

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Arrestins; beta-Arrestins; Drug Tolerance; Fentan

2011
(1) H-nuclear magnetic resonance-based metabonomic analysis of brain in rhesus monkeys with morphine treatment and withdrawal intervention.
    Journal of neuroscience research, 2012, Volume: 90, Issue:11

    Topics: Animals; Brain; Disease Models, Animal; Female; Macaca mulatta; Magnetic Resonance Spectroscopy; Mal

2012
Clinical characteristics of addictions.
    The American journal of medicine, 1953, Volume: 14, Issue:5

    Topics: Barbiturates; Cannabis; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Su

1953
RAPID diagnosis of addiction to morphine.
    Journal of the American Medical Association, 1954, Jan-30, Volume: 154, Issue:5

    Topics: Behavior, Addictive; Methadone; Morphine; Morphine Dependence; Nalorphine; Substance-Related Disorde

1954
Lower limb reflexes of a "chronic spinal" man in cycles of morphine and methadone addition.
    A.M.A. archives of neurology and psychiatry, 1954, Volume: 71, Issue:2

    Topics: Behavior, Addictive; Humans; Lower Extremity; Male; Methadone; Morphine; Morphine Dependence; Reflex

1954
Drug addiction and other considerations in the management of pain with narcotic drugs.
    Proceedings of the staff meetings. Mayo Clinic, 1957, Feb-06, Volume: 32, Issue:3

    Topics: Behavior, Addictive; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Narco

1957
Drug addiction and other considerations in the management of pain with narcotic drugs.
    Proceedings of the staff meetings. Mayo Clinic, 1957, Feb-06, Volume: 32, Issue:3

    Topics: Behavior, Addictive; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Narco

1957
Drug addiction and other considerations in the management of pain with narcotic drugs.
    Proceedings of the staff meetings. Mayo Clinic, 1957, Feb-06, Volume: 32, Issue:3

    Topics: Behavior, Addictive; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Narco

1957
Drug addiction and other considerations in the management of pain with narcotic drugs.
    Proceedings of the staff meetings. Mayo Clinic, 1957, Feb-06, Volume: 32, Issue:3

    Topics: Behavior, Addictive; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Narco

1957
[Semiquantitative determination of physical dependence in morphine and methadon therapy].
    Archiv fur Psychiatrie und Nervenkrankheiten, vereinigt mit Zeitschrift fur die gesamte Neurologie und Psychiatrie, 1959, Volume: 199, Issue:1

    Topics: Depression; Depressive Disorder; Humans; Methadone; Morphine; Morphine Dependence; Substance-Related

1959
EXPERIMENTAL NARCOTIC ADDICTION.
    Scientific American, 1964, Volume: 210

    Topics: Animals; Codeine; Conditioning, Psychological; Equipment and Supplies; Haplorhini; Injections, Intra

1964
BARBITURATE USE IN NARCOTIC ADDICTS.
    JAMA, 1964, Aug-03, Volume: 189

    Topics: Barbiturates; Codeine; Drug Tolerance; Ethchlorvynol; Glutethimide; Heroin; Hydromorphone; Hypnotics

1964
CONGENITAL NEONATAL NARCOTICS ADDICTION: A NATURAL HISTORY.
    American journal of public health and the nation's health, 1964, Volume: 54

    Topics: Chlorpromazine; Female; Humans; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine Dependence;

1964
RELATIVE POTENCY OF CODEINE, METHADONE AND DIHYDROMORPHINONE TO MORPHINE IN SELF-MAINTAINED ADDICT RATS.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1965, Jan-08, Volume: 249

    Topics: Codeine; Hydromorphone; Methadone; Morphine; Morphine Dependence; Periodicity; Pharmacology; Rats; R

1965
German project to treat drug addicts not extended despite good results.
    BMJ (Clinical research ed.), 2007, Feb-24, Volume: 334, Issue:7590

    Topics: Germany; Health Policy; Heroin; Humans; Methadone; Morphine Dependence

2007
The biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain.
    Pharmacology, 2007, Volume: 79, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics, Opioid; Animals; Brain; Dose-Response Re

2007
Dentition of addiction in Queensland: poor dental status and major contributing drugs.
    Australian dental journal, 2007, Volume: 52, Issue:2

    Topics: Adult; Age Factors; Alcohol-Related Disorders; Amphetamine-Related Disorders; Cross-Sectional Studie

2007
Hepatitis C treatment, subcutaneous naltrexone implants, and methadone maintenance treatment.
    Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:3

    Topics: Antiviral Agents; Drug Implants; Hepatitis C; Humans; Methadone; Morphine Dependence; Naltrexone; Na

2007
The addiction liability of methadon (amidone, dolophine, 10820) and its use in the treatment of the morphine abstinence syndrome.
    The American journal of psychiatry, 1949, Volume: 105, Issue:12

    Topics: Behavior, Addictive; Humans; Industry; Methadone; Morphine; Morphine Dependence; Occupations; Syndro

1949
The present status of methadone blockade treatment.
    The American journal of psychiatry, 1967, Volume: 123, Issue:11

    Topics: Heroin; Humans; Methadone; Morphine Dependence

1967
Effect of acute methadone withdrawal on prostaglandin E-stimulated 3H-cyclic adenosine monophosphate accumulation in human platelets.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:5

    Topics: Adenylyl Cyclases; Blood Platelets; Cell Line; Cyclic AMP; Humans; Methadone; Morphine Dependence; N

1980
Seven year follow-up of 300 young drug abusers.
    Acta psychiatrica Scandinavica, 1984, Volume: 70, Issue:5

    Topics: Adult; Denmark; Female; Follow-Up Studies; Humans; Male; Methadone; Morphine Dependence; Rehabilitat

1984
[Condition of 89 newborn infants of drug-addicted mothers].
    Ugeskrift for laeger, 1983, Feb-21, Volume: 145, Issue:8

    Topics: Abnormalities, Drug-Induced; Adult; Apgar Score; Female; Heroin Dependence; Humans; Infant, Low Birt

1983
[1967-82, an evaluation of the Swedish experience with maintenance methadone therapy of morphine addicts].
    Minerva medica, 1982, Dec-08, Volume: 73, Issue:47

    Topics: Follow-Up Studies; Health Services Needs and Demand; Humans; Methadone; Morphine Dependence; Statist

1982
Tolerance to methadone lethality and microsomal enzyme induction in mice tolerant to and dependent on morphine.
    Drug and alcohol dependence, 1980, Volume: 5, Issue:1

    Topics: Animals; Body Weight; Drug Tolerance; Enzyme Induction; Humans; Inactivation, Metabolic; Lethal Dose

1980
Suppression of withdrawal jumping: comparison of narcotic tolerance and dependence.
    Drug and alcohol dependence, 1980, Volume: 5, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Male; Methadone; Mice; Mice, Inbr

1980
Relapse to morphine self-administration in morphine, methadone, and levo-alpha-acetylmethadol (LAAM) post-addict rats.
    Drug and alcohol dependence, 1981, Volume: 7, Issue:2

    Topics: Animals; Female; Humans; Methadone; Methadyl Acetate; Morphine Dependence; Rats; Self Administration

1981
Clinical pharmacology of mixed agonist-antagonist drugs [proceedings].
    Psychopharmacology bulletin, 1981, Volume: 17, Issue:1

    Topics: Buprenorphine; Cyclazocine; Humans; Methadone; Morphinans; Morphine Dependence; Naltrexone

1981
Morphine and methadone maintenance clinics.
    The New England journal of medicine, 1981, Aug-20, Volume: 305, Issue:8

    Topics: Humans; Methadone; Morphine Dependence; New York City

1981
Strength of drug habits: for heroin, morphine, methadone, alcohol, barbiturates, pentobarbital, benzedrine, cocaine, and marijuana.
    Drug and alcohol dependence, 1980, Volume: 5, Issue:6

    Topics: Adult; Alcoholism; Amphetamines; Barbiturates; Cannabis; Cocaine; Heroin Dependence; Humans; Male; M

1980
[Report on prescriptions of methadone at the Espace Murger, Hôpital F.-Widal (1984-1993)].
    Annales de medecine interne, 1994, Volume: 145 Suppl 3

    Topics: Adult; Benzodiazepines; Drug Prescriptions; Female; Heroin Dependence; Humans; Male; Methadone; Midd

1994
Drug-related deaths during the 1980s. A comparative study of drug addict deaths examined at the institutes of forensic medicine in Aarhus, Denmark and Oslo, Norway.
    International journal of legal medicine, 1993, Volume: 106, Issue:1

    Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Cause of Death; Cross-Cultural Comp

1993
Methadone and drug addicts.
    International journal of legal medicine, 1993, Volume: 106, Issue:3

    Topics: Adolescent; Adult; Alcoholism; Benzodiazepines; Cause of Death; Child; Denmark; Female; Forensic Med

1993
The relationship of methadone dose and other variables to outcomes of methadone maintenance.
    The American journal on addictions, 1997,Summer, Volume: 6, Issue:3

    Topics: Adult; Cocaine; Dose-Response Relationship, Drug; Female; Humans; Male; Methadone; Morphine Dependen

1997
[Central nervous system activation in opioid dependent patients, evaluation with Fourier analysis of pupillary oscillations].
    Wiener klinische Wochenschrift, 2000, Jan-28, Volume: 112, Issue:2

    Topics: Adult; Brain; Dose-Response Relationship, Drug; Female; Fourier Analysis; Heroin Dependence; Humans;

2000
Safety, efficacy, and long-term results of a modified version of rapid opiate detoxification under general anaesthesia: a prospective study in methadone, heroin, codeine and morphine addicts.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:3

    Topics: Adult; Anesthesia, General; Codeine; Female; Heroin Dependence; Humans; Male; Methadone; Morphine De

2000
Nervous regulation of breathing in opiate dependent patient. Part II. Respiratory system efficiency and breathing regulation of persons classified to the methadone maintenance treatment.
    Przeglad lekarski, 2000, Volume: 57, Issue:10

    Topics: Adult; Female; Heroin Dependence; Humans; Male; Methadone; Morphine Dependence; Narcotics; Pons; Res

2000
Opioid addiction changes cerebral blood flow symmetry.
    Neuropsychobiology, 2002, Volume: 45, Issue:2

    Topics: Adult; Case-Control Studies; Cerebrovascular Circulation; Female; Functional Laterality; Heroin Depe

2002
Adjunctive drug use by methadone patients.
    The American journal of drug and alcohol abuse, 1977, Volume: 4, Issue:4

    Topics: Alcohol Drinking; Anti-Anxiety Agents; Costs and Cost Analysis; Ethanol; Heroin Dependence; Humans;

1977
Management of surgical problems in patients on methadone maintenance.
    American journal of surgery, 1976, Volume: 131, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Cocaine; Female; Heroin Dependence; Humans; Hydromorph

1976
Animal-human correlates of narcotic dependence: a brief review.
    The American journal of psychiatry, 1978, Volume: 135, Issue:7

    Topics: Animals; Behavior Therapy; Conditioning, Operant; Disease Models, Animal; Dogs; Drug Tolerance; Hapl

1978
The effect of l-alpha acetyl methadol in morphine-dependent rats.
    NIDA research monograph, 1979, Volume: 27

    Topics: Animals; Body Weight; Female; Humans; Injections, Intraperitoneal; Methadone; Methadyl Acetate; Morp

1979
Human sleep during chronic morphine intoxication.
    Psychopharmacologia, 1975, Oct-31, Volume: 44, Issue:2

    Topics: Adult; Alpha Rhythm; Arousal; Delta Rhythm; Drug Tolerance; Humans; Male; Methadone; Morphine; Morph

1975
1-alpha-acetylmethadol (LAAM), methadone and morphine abstinence in dependent rats: EEG and behavioral correlates.
    Drug and alcohol dependence, 1977, Volume: 2, Issue:2

    Topics: Animals; Behavior, Animal; Electroencephalography; Electromyography; Female; Humans; Methadone; Meth

1977
Transitional patterns of self-administration following substitution of methadone or l-alpha-acetylmethadol (LAAM) for morphine in dependent rats.
    Drug and alcohol dependence, 1978, Volume: 3, Issue:4

    Topics: Animals; Electroencephalography; Electromyography; Humans; Male; Methadone; Methadyl Acetate; Morphi

1978
Spontaneous vs. naloxone-induced abstinence in dependent rats self-administering L-alpha-acetylmethadol (LAAM) or morphine.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:4

    Topics: Animals; Female; Humans; Methadone; Methadyl Acetate; Morphine Dependence; Naloxone; Rats; Self Admi

1979
Head-shake distributions during self-maintained dependence on morphine, methadone, and l-alpha-acetylmethadol (LAAM) in the rat.
    Psychopharmacology, 1977, Aug-31, Volume: 54, Issue:1

    Topics: Animals; Behavior, Animal; Female; Humans; Methadone; Methadyl Acetate; Morphine; Morphine Dependenc

1977
Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users.
    The Journal of pediatrics, 1979, Volume: 94, Issue:6

    Topics: Amphetamine; Cocaine; Diazepam; Female; Heroin Dependence; Humans; Infant; Infant, Newborn; Infant,

1979
[Hepatic histopathological aspects and humoral findings in drug addicts: critical considerations on 37 cases].
    Recenti progressi in medicina, 1979, Volume: 67, Issue:1

    Topics: Adolescent; Adult; Alanine Transaminase; Alcoholism; Amphetamines; Aspartate Aminotransferases; Benz

1979
Analysis of reinforcement during intragastric self-administration of morphine and methadone in the rat.
    Communications in psychopharmacology, 1977, Volume: 1, Issue:1

    Topics: Animals; Humans; Intubation; Male; Methadone; Morphine; Morphine Dependence; Rats; Reinforcement, Ps

1977
Acute inhibition of microsomal drug metabolism by propoxyphene in narcotic tolerant/dependent mice.
    Life sciences, 1978, Jun-19, Volume: 22, Issue:23

    Topics: Animals; Dextropropoxyphene; Drug Tolerance; Humans; Male; Methadone; Mice; Microsomes, Liver; Mixed

1978
Antidiuretic effect of morphine in the rat: tolerance and physical dependence.
    British journal of pharmacology, 1978, Volume: 64, Issue:2

    Topics: Animals; Diuresis; Drug Implants; Drug Tolerance; Humans; Injections, Intraperitoneal; Methadone; Mo

1978
Tolerance, dependence and lethality in morphine-dependent mice after repeated oral administration of methadone.
    Drug and alcohol dependence, 1978, Volume: 3, Issue:6

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Implants; Humans; Male; Methad

1978
Dose-time motility effects of morphine and methadone in naive or morphinized rats.
    Pharmacological research communications, 1979, Volume: 11, Issue:9

    Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Male; Methadone; Morphine; Morphi

1979
[Morphine intoxication and abstinence].
    Lakartidningen, 1977, Nov-30, Volume: 74, Issue:48

    Topics: Dextropropoxyphene; Drug Tolerance; Heroin; Heroin Dependence; Humans; Methadone; Morphine; Morphine

1977
[The Swedish methadone rehabilitation program 1967-1977].
    Lakartidningen, 1977, Nov-30, Volume: 74, Issue:48

    Topics: Adult; Day Care, Medical; Evaluation Studies as Topic; Follow-Up Studies; Heroin Dependence; Humans;

1977
Indigenous and expatriate addicts in Laos: a comparison.
    Culture, medicine and psychiatry, 1978, Volume: 2, Issue:2

    Topics: Adult; Age Factors; Aged; Costs and Cost Analysis; Emigration and Immigration; Female; Heroin Depend

1978
Drug self-administration and sleep-awake activity in rats dependent on morphine, methadone, or l-alpha-acetylmethadol.
    Psychopharmacology, 1976, Jun-23, Volume: 47, Issue:3

    Topics: Animals; Female; Humans; Methadone; Morphine Dependence; Rats; Self Stimulation; Sleep; Substance-Re

1976
Evaluation of narcotic and narcotic antagonist interactions in primates.
    Annals of the New York Academy of Sciences, 1976, Volume: 281

    Topics: Animals; Cyclazocine; Dextroamphetamine; Diazepam; Drug Interactions; Ethanol; Female; Haplorhini; H

1976
Methadone maintenance in a patient on chronic hemodialysis.
    The American journal of psychiatry, 1977, Volume: 134, Issue:8

    Topics: Aggression; Humans; Male; Methadone; Middle Aged; Morphine Dependence; Renal Dialysis; Substance Wit

1977
Drug abuse report from Denmark.
    Addictive diseases, 1977, Volume: 3, Issue:1

    Topics: Adult; Barbiturates; Denmark; Female; Humans; Male; Mental Health Services; Methadone; Morphine Depe

1977
Hostility in drug dependent individuals: its relation to specific drugs, and oral or intravenous use.
    The British journal of psychiatry : the journal of mental science, 1976, Volume: 128

    Topics: Acting Out; Administration, Oral; Adult; Amphetamines; Delusions; Female; Guilt; Heroin Dependence;

1976
A dose-response comparison between methadone and morphine self-administration.
    Psychopharmacologia, 1976, May-28, Volume: 47, Issue:2

    Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Humans; Male; Methadone; Morphine;

1976
A city looks at its problem of drug abuse by injection.
    The British journal of psychiatry : the journal of mental science, 1976, Volume: 129

    Topics: Adult; Age Factors; Barbiturates; Crime; Drug Prescriptions; England; Female; Heroin Dependence; Hos

1976
Actions and addiction liabilities of alpha-acetylmethadols in man. 1952 [proceedings].
    NIDA research monograph, 1976, Issue:8

    Topics: Adult; Drug Administration Schedule; Humans; Male; Methadone; Methadyl Acetate; Miotics; Morphine De

1976
Acute pulmonary alveolitis in narcotics abuse.
    Archives of pathology, 1975, Volume: 99, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Angiography; Cocaine; Female; Foreign Bodies; Foreign-Body Reactio

1975
Pharmacological approaches to the treatment of morphine-type dependence.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Cyclazocine; Drug Therapy, Combination; Drug Tolerance; Humans; Methadone; Morphine Dependence; Nalo

1975
Blockade by narcotic drugs of naloxone-precipitated jumping in morphine-dependent mice.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:1

    Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Codeine; Dextropropoxyphene; Dose-Resp

1975
The offset of morphine tolerance in rats and mice.
    British journal of pharmacology, 1975, Volume: 53, Issue:3

    Topics: Analgesics; Animals; Behavior, Animal; Drug Tolerance; Humans; Methadone; Mice; Morphine; Morphine D

1975
Possible role of brain histamine in morphine addiction.
    Life sciences, 1975, Jul-01, Volume: 17, Issue:1

    Topics: Animals; Brain; Brain Stem; Cerebral Cortex; Histamine; Humans; Hypothalamus; Male; Methadone; Morph

1975
Effects of narcotic agonists and antagonists on schedule-induced water and morphine ingestion.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:2

    Topics: Animals; Cyclazocine; Drinking Behavior; Humans; Methadone; Morphine; Morphine Dependence; Nalorphin

1975
Attenuation of precipitated abstinence in methadone-dependent rats by delta 9-THC.
    Psychopharmacology communications, 1975, Volume: 1, Issue:3

    Topics: Animals; Behavior, Animal; Cannabis; Dronabinol; Drug Tolerance; Humans; Male; Methadone; Morphine D

1975
Morphine and methadone dependence in the rat: withdrawal and brain met-enkephalin levels.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:1

    Topics: Animals; Behavior, Animal; Body Weight; Brain Chemistry; Drinking; Enkephalin, Methionine; Female; M

1992
Evidence of single dose opioid dependence in 12- to 14-day-old chicken embryos.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamid

1989
Morphine and methadone impact on human phagocytic physiology.
    International journal of immunopharmacology, 1985, Volume: 7, Issue:6

    Topics: Cytotoxicity, Immunologic; Humans; Immunosuppressive Agents; Methadone; Monocytes; Morphine Dependen

1985
Mechanisms of the contractile responses to morphine of the mouse colon in vitro.
    General pharmacology, 1988, Volume: 19, Issue:5

    Topics: Animals; Colon; In Vitro Techniques; Methadone; Mice; Morphine; Morphine Dependence; Muscle Contract

1988
Differential modification of morphine and methadone dependence by interferon alpha.
    Neuropharmacology, 1987, Volume: 26, Issue:11

    Topics: Animals; Behavior, Animal; Interferon Type I; Male; Methadone; Morphine Dependence; Opioid-Related D

1987
Aspects of abstinence after morphine ingestion.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:1

    Topics: Animals; Body Weight; Diarrhea; Dose-Response Relationship, Drug; Drinking; Male; Methadone; Methods

1987
Cross-sensitization to the excitatory effect of morphine in post-dependent rats.
    Neuropharmacology, 1985, Volume: 24, Issue:9

    Topics: Animals; Male; Meperidine; Methadone; Morphine; Morphine Dependence; Motor Activity; Pentazocine; Ra

1985
The search for a better analgesic.
    Science (New York, N.Y.), 1973, Aug-03, Volume: 181, Issue:4098

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Heroin; Humans; Hydromorphone; Levorpha

1973
[Surreptitious acquisition of medical prescriptions. Criminologic studies on drugs and deliquency].
    Medizinische Klinik, 1974, Feb-08, Volume: 69, Issue:6

    Topics: Adolescent; Adult; Central Nervous System Stimulants; Criminology; Deception; Diazepam; Drug and Nar

1974
Letter: Brain adenyl cyclase in methadone treatment of morphine dependency.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:12

    Topics: Adenylyl Cyclases; Animals; Brain; Humans; Male; Methadone; Morphine Dependence; Phosphoric Diester

1973
[Discussion on methadone programs in the Federal Republic of Germany].
    Deutsche medizinische Wochenschrift (1946), 1973, Volume: 98, Issue:43

    Topics: Ambulatory Care; Female; Germany, West; Heroin Dependence; Hospitalization; Humans; Long-Term Care;

1973
Parachlorophenylalanine, serotonin and sleep.
    The British journal of psychiatry : the journal of mental science, 1973, Volume: 122, Issue:569

    Topics: Animals; Drug Tolerance; Fenclonine; Humans; Methadone; Mice; Morphine Dependence; Rats; Serotonin;

1973
[Narcotic addiction: a new social scourage in Europe].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1971, Dec-26, Volume: 47, Issue:53

    Topics: Adolescent; Adult; Dextromoramide; Drug and Narcotic Control; Europe; Female; Heroin; Humans; Legisl

1971
The significance of diagnosis in the treatment of narcotics addicts.
    The International journal of the addictions, 1970, Volume: 5, Issue:4

    Topics: Adult; Anxiety; Community Health Services; Depression; Evaluation Studies as Topic; Heroin; Humans;

1970
A single-dose suppression test in morphine-dependent mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 145, Issue:4

    Topics: Aminopyrine; Analgesics; Animals; Behavior, Animal; Humans; Isonipecotic Acids; Levorphanol; Male; M

1974
Short-term, ambulatory detoxification of opiate addicts using methadone.
    The International journal of the addictions, 1974, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Ambulatory Care; Germany, West; Heroin Dependence; Humans; Male; Methadone; Milit

1974
[Previous opiate addictions: trial of substitutive therapy using methadone chlorhydrate].
    Annales de medecine interne, 1974, Volume: 125, Issue:5

    Topics: Administration, Oral; Adult; Ambulatory Care; Codeine; Female; Heroin Dependence; Hospitalization; H

1974
[Preliminary trials with methadone in the treatment of opiate addictions].
    Annales de medecine interne, 1974, Volume: 125, Issue:5

    Topics: Administration, Oral; Adult; Female; Heroin Dependence; Humans; Male; Methadone; Morphine Dependence

1974
Induction of physical dependence on morphine, codeine and meperidine in the rat by continuous infusion.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:3

    Topics: Animals; Behavior, Animal; Body Weight; Codeine; Dose-Response Relationship, Drug; Humans; Infusions

1974
Treatment of middle class heroin abusers: preliminary observations.
    The Medical annals of the District of Columbia, 1972, Volume: 41, Issue:5

    Topics: Adult; Female; Heroin; Humans; Male; Methadone; Middle Aged; Morphine Dependence; Psychotherapy, Gro

1972
Methadone maintenance treatment of narcotic addiction. Analysis of police records of arrests before and during treatment.
    New York state journal of medicine, 1972, Jul-01, Volume: 72, Issue:13

    Topics: Crime; Humans; Methadone; Morphine Dependence; New York City

1972
Methadone and addiction.
    The New Zealand medical journal, 1972, Volume: 76, Issue:482

    Topics: Drug and Narcotic Control; Heroin; Humans; Methadone; Morphine Dependence; New Zealand; Substance-Re

1972
Modification of precipitated morphine and methadone abstinence in mice by acetylcholine antagonists.
    Nature: New biology, 1973, Oct-17, Volume: 245, Issue:146

    Topics: Acetylcholine; Animals; Atropine; Drug Combinations; Humans; Mecamylamine; Methadone; Mice; Morphine

1973
Studies on physical dependence inducible by hours exposure of mice to morphine.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:6

    Topics: Analgesia; Animals; Behavior, Animal; Body Weight; Drug Tolerance; Humans; Infusions, Parenteral; In

1972
A scoring system for abstinence syndrome in morphine dependent mice and application to evaluate morphine type dependence liability of drugs.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:5

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Humans; Male; Meperidine; Methadone; Mi

1973
Legal and social aspects of drug abuse in historical perspective. Is the drug abuser a patient or a criminal?
    Adolescence, 1974,Winter, Volume: 9, Issue:36

    Topics: China; Criminal Psychology; Drug and Narcotic Control; Emigration and Immigration; Government Agenci

1974
Heroin addiction and the role of methadone in its treatment.
    Archives of general psychiatry, 1972, Volume: 26, Issue:4

    Topics: Animals; Anxiety; Compulsive Behavior; Conditioning, Classical; Conditioning, Operant; Dogs; Drug To

1972
Addiction and the community. (Narcotic substitution therapy).
    International journal of clinical pharmacology, therapy and toxicology, 1972, Volume: 6, Issue:1

    Topics: Health Expenditures; History, 20th Century; Humans; Methadone; Morphine Dependence; Narcotic Antagon

1972
Methadone--curse or cure?
    Medical times, 1972, Volume: 100, Issue:11

    Topics: Adult; Drug and Narcotic Control; Humans; Male; Methadone; Morphine Dependence; United States

1972
[Clinical pharmacology of narcotics. II].
    Hippokrates, 1972, Volume: 43, Issue:4

    Topics: Chemical Phenomena; Chemistry; Hallucinogens; Humans; Lysergic Acid Diethylamide; Meperidine; Methad

1972
Methadone maintenance: myth and reality.
    The American journal of psychiatry, 1972, Volume: 129, Issue:4

    Topics: Costs and Cost Analysis; Criminal Psychology; Drug Tolerance; Evaluation Studies as Topic; Heroin; H

1972
Treatment of chemical dependency of the morphine type.
    Minnesota medicine, 1973, Volume: 56, Issue:3

    Topics: Dose-Response Relationship, Drug; Heroin; Heroin Dependence; Humans; Methadone; Morphine Dependence;

1973
The drug scene: acute drug syndromes.
    Postgraduate medicine, 1973, Volume: 53, Issue:4

    Topics: Alcoholic Intoxication; Amphetamine; Atropa belladonna; Atropine; Barbiturates; Cannabis; Diagnosis,

1973
Treatment facilities for drug-dependent patients. Some impressions of treatment programmes in the United States and Canada.
    The Medical journal of Australia, 1973, Apr-21, Volume: 1, Issue:16

    Topics: Adolescent; Age Factors; Canada; Child; Heroin Dependence; Hospitals, General; Hospitals, Psychiatri

1973
[A case of staphylococcemia with tricuspid and pulmonary localization in a morphine addict].
    Annales de medecine interne, 1973, Volume: 124, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Cephaloridine; Cephalothin; Endocarditis, Bacterial; Fever; Humans;

1973
Effect of dopaminergic stimulation or blockade on morphine-withdrawal aggression.
    Psychopharmacologia, 1973, Volume: 32, Issue:2

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Dihydroxyphenylalanine; Haloperidol; Humans; Male; Me

1973
Physiologic implications of methadone treatment.
    Proceedings. National Conference on Methadone Treatment, 1973, Volume: 2

    Topics: Adult; Alcoholism; Drug Tolerance; Electrocardiography; Female; Heroin Dependence; Hospitalization;

1973
Methadone-naloxone mixtures for use in methadone maintenance programs. I. An evaluation in man of their pharmacological feasibility. II. Demonstration of acute physical dependence.
    Clinical pharmacology and therapeutics, 1974, Volume: 15, Issue:2

    Topics: Drug Therapy, Combination; Filtration; Heroin Dependence; Humans; Male; Methadone; Morphine Dependen

1974
Chlorodyne dependence.
    British medical journal, 1974, Mar-09, Volume: 1, Issue:5905

    Topics: Adult; Capsicum; Chloroform; Drug Combinations; Ethanol; Female; Humans; London; Male; Methadone; Mi

1974
Reciprocal (push-pull) effects of morphine on single units in the ventromedian and lateral hypothalamus and influences on other nuclei: with a comment on methadone effects during withdrawal from morphine.
    Brain research, 1974, Jul-05, Volume: 74, Issue:1

    Topics: Amygdala; Animals; Cerebral Cortex; Depression, Chemical; Drug Interactions; Electrophysiology; Huma

1974
Alterations in striatal acetylcholine, acetylcholine esterase and dopamine after methadone replacement in morphine-dependent rats.
    European journal of pharmacology, 1974, Volume: 26, Issue:2

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Brain Chemistry; Corpus Striatum; Dopamine; Humans; Ma

1974
Letter: Methadone maintenance.
    JAMA, 1974, Jan-14, Volume: 227, Issue:2

    Topics: Humans; Legislation, Drug; Methadone; Morphine Dependence; Substance Withdrawal Syndrome; United Sta

1974
Drug abuse treatment programs. Kicking the habit.
    Hospitals, 1971, Aug-01, Volume: 45, Issue:15

    Topics: History, 19th Century; History, 20th Century; Hospitalization; Humans; Methadone; Morphine Dependenc

1971
A bibliography of the methadone maintenance treatment of heroin addiction.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Bibliographies as Topic; Heroin; Humans; Methadone; Morphine Dependence; Substance Withdrawal Syndro

1970
WHO Expert Committee on Drug Dependence. Seventeenth report.
    World Health Organization technical report series, 1970, Volume: 437

    Topics: Drug and Narcotic Control; Humans; Methadone; Morphine Dependence; Substance-Related Disorders; Worl

1970
Methadone treatment of narcotic addiction.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:4

    Topics: Costs and Cost Analysis; Crime; Health Expenditures; Heroin; Humans; Methadone; Morphine Dependence;

1971
Heroin addiction treatment and crime reduction.
    The American journal of psychiatry, 1972, Volume: 128, Issue:7

    Topics: Adult; Counseling; Crime; District of Columbia; Female; Follow-Up Studies; Government Agencies; Hero

1972
Failure of outpatient treatment of drug abuse. I. Heroin.
    The American journal of psychiatry, 1972, Volume: 128, Issue:7

    Topics: Adolescent; Adult; Appointments and Schedules; Cooperative Behavior; Female; Follow-Up Studies; Hero

1972
Five years after: a follow-up of 50 narcotic addicts.
    The American journal of psychiatry, 1972, Volume: 128, Issue:7

    Topics: Adolescent; Adult; Aged; Cannabis; Crime; Female; Follow-Up Studies; Heroin; Humans; Interpersonal R

1972
U.S. Army heroin abuse identification program in Vietnam: implications for a methadone program.
    American journal of public health, 1972, Volume: 62, Issue:6

    Topics: Chromatography, Gas; Chromatography, Thin Layer; False Positive Reactions; Heroin; Humans; Methadone

1972
Narcotics and the community: a system stimulation.
    American journal of public health, 1972, Volume: 62, Issue:6

    Topics: Attitude to Health; Computers; Crime; Drug and Narcotic Control; Health Education; Humans; Methadone

1972
Impressions of early problems in a community-initiated methadone program.
    Hospital & community psychiatry, 1972, Volume: 23, Issue:7

    Topics: Community Mental Health Services; Counseling; Heroin; Humans; Maryland; Methadone; Morphine Dependen

1972
Maintenance methadone treatment of drug dependency.
    Canadian Psychiatric Association journal, 1972, Volume: 17, Issue:2

    Topics: Administration, Oral; Adult; Constipation; Erectile Dysfunction; Evaluation Studies as Topic; Female

1972
Narcotics addiction 1972--an overview.
    American journal of psychotherapy, 1972, Volume: 26, Issue:3

    Topics: Adolescent; Child; Heroin; Humans; Methadone; Morphine Dependence; Narcotics; Substance-Related Diso

1972
Entry into methadone maintenance programs: a follow-up study of New York City heroin users detoxified in 1961-1963.
    American journal of public health, 1972, Volume: 62, Issue:7

    Topics: Adult; Age Factors; Ethnicity; Family Characteristics; Female; Follow-Up Studies; Heroin; Humans; Ma

1972
On the treatment of stimulant abuse.
    Perspectives in biology and medicine, 1972,Summer, Volume: 15, Issue:4

    Topics: Cyclazocine; Humans; Methadone; Morphine Dependence; Psychotherapy; Reinforcement, Social; Social Ch

1972
Heroin addicts in a community mental health inpatient unit.
    The American journal of psychiatry, 1972, Volume: 129, Issue:2

    Topics: Adult; California; Community Mental Health Services; Female; Heroin; Hospitalization; Hospitals, Tea

1972
The changing face of heroin addiction in the Haight-Ashbury.
    The International journal of the addictions, 1972, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Amphetamine; California; Cannabis; Child; Community Health Services; Female; Hero

1972
Present-day methadone prescribing in England.
    The International journal of the addictions, 1972, Volume: 7, Issue:1

    Topics: Dosage Forms; Drug Prescriptions; Drug Utilization; England; Heroin; Humans; Legislation, Drug; Meth

1972
Heroin addicts' views of commonly abused drugs: a semantic differential approach.
    Journal of personality assessment, 1972, Volume: 36, Issue:4

    Topics: Adult; Amphetamine; Cannabis; Female; Heroin; Humans; Lysergic Acid Diethylamide; Male; Methadone; M

1972
"Cold turkey" in the newborn.
    The Medical journal of Australia, 1972, Feb-19, Volume: 1, Issue:8

    Topics: Adult; Australia; Diagnosis, Differential; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange;

1972
Helping alcoholics abstain: an implantable substance.
    The American journal of psychiatry, 1972, Volume: 129, Issue:3

    Topics: Alcohol Drinking; Alcoholism; Cannabis; Delayed-Action Preparations; Disulfiram; Heroin; Humans; Met

1972
A pilot methadone program to introduce comprehensive addiction treatment.
    Hospital & community psychiatry, 1972, Volume: 23, Issue:3

    Topics: Adult; Community Health Services; Female; Financing, Government; Heroin; Humans; Male; Methadone; Mo

1972
Treatment of a pregnant opiate addict with oral methadone.
    Arizona medicine, 1972, Volume: 29, Issue:2

    Topics: Administration, Oral; Adult; Female; Heroin; Humans; Infant, Newborn; Infant, Newborn, Diseases; Met

1972
Methadone maintenance: limit setting.
    The American journal of psychiatry, 1972, Volume: 128, Issue:9

    Topics: Humans; Methadone; Morphine Dependence

1972
Resumption of morphine self-administration by ex-addict rats: an attempt to modify tendencies to relapse.
    Journal of comparative and physiological psychology, 1972, Volume: 78, Issue:3

    Topics: Animals; Disease Models, Animal; Drinking Behavior; Humans; Male; Methadone; Morphine; Morphine Depe

1972
Treatment of morphine-type dependence.
    JAMA, 1972, Sep-25, Volume: 221, Issue:13

    Topics: Female; Gestational Age; Heroin; Humans; Male; Methadone; Morphine Dependence; Pregnancy; Substance

1972
[Morphine withdrawal treatment in 197 admissions for opiates].
    Lakartidningen, 1972, May-24, Volume: 69, Issue:22

    Topics: Adult; Humans; Methadone; Morphine Dependence; Substance Withdrawal Syndrome

1972
Critique of success with methadone maintenance.
    The American journal of psychiatry, 1972, Volume: 129, Issue:4

    Topics: Adult; Criminal Psychology; Employment; Evaluation Studies as Topic; Follow-Up Studies; Heroin; Hosp

1972
Methadone: some aspects of its legal and illegal use.
    The American journal of psychiatry, 1972, Volume: 129, Issue:4

    Topics: Adult; Cocaine; Criminal Psychology; Drug and Narcotic Control; Female; Heroin; Humans; Male; Methad

1972
Prevalence of participation in methadone programs.
    The American journal of psychiatry, 1972, Volume: 129, Issue:4

    Topics: Adolescent; Adult; Ambulatory Care; Evaluation Studies as Topic; Female; Heroin; Hospitalization; Hu

1972
Methadone maintenance: expanding the concept of service.
    The American journal of psychiatry, 1972, Volume: 129, Issue:4

    Topics: Criminal Psychology; Heroin; Humans; Methadone; Morphine Dependence; Rehabilitation, Vocational; Sub

1972
Personality correlates of success in a methadone maintenance program.
    The American journal of psychiatry, 1972, Volume: 129, Issue:4

    Topics: Adult; Anxiety; Black or African American; Community Health Services; Cooperative Behavior; Counseli

1972
Human chromosomes and opiates.
    Archives of general psychiatry, 1972, Volume: 27, Issue:4

    Topics: Adult; Cells, Cultured; Chromosome Aberrations; Chromosomes; Dose-Response Relationship, Drug; Femal

1972
Flushing, pale-colored urines, and false negatives. Urinalysis of narcotic addicts.
    The International journal of the addictions, 1972,Summer, Volume: 7, Issue:2

    Topics: Chromatography, Thin Layer; Color; False Negative Reactions; Heroin; Humans; Methadone; Morphine Dep

1972
Neonatal addiction to methadone.
    Pediatrics, 1971, Volume: 47, Issue:4

    Topics: Female; Heroin; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Methado

1971
The operation of the data system in the methadone maintenance treatment program for heroin addiction.
    American journal of public health, 1971, Volume: 61, Issue:10

    Topics: Community Health Services; Computers; Demography; Heroin; Hospitals; Humans; Information Services; I

1971
Methadone maintenance treatment of heroin addiction.
    Delaware medical journal, 1971, Volume: 43, Issue:9

    Topics: Administration, Oral; Heroin; Humans; Methadone; Morphine Dependence

1971
The social structure of a heroin copping community.
    The American journal of psychiatry, 1971, Volume: 128, Issue:5

    Topics: Age Factors; Chicago; Demography; Female; Group Structure; Heroin; Humans; Male; Mental Health; Meth

1971
The treatment and rehabilitation of heroin addicts.
    Michigan medicine, 1971, Volume: 70, Issue:28

    Topics: Adult; Community Health Services; Female; Heroin; Humans; Male; Methadone; Michigan; Morphine Depend

1971
Drug abuse programs: are hospitals too late and too square?
    Hospitals, 1971, Jan-16, Volume: 45, Issue:2

    Topics: Attitude of Health Personnel; Attitude to Health; Behavior Therapy; Emergency Medical Services; Hero

1971
The relative value of the medical staff versus addicts in the rehabilitation of the drug users in a drug abuse program.
    The Johns Hopkins medical journal, 1971, Volume: 129, Issue:5

    Topics: Adult; Age Factors; Black or African American; Female; Heroin; Humans; Life Style; Male; Maryland; M

1971
Fertility of narcotics addicts and effects of addiction on the offspring.
    Social biology, 1971, Volume: 18

    Topics: Female; Fertility; Heroin; Humans; Infant, Newborn; Maternal-Fetal Exchange; Methadone; Morphine Dep

1971
Neonatal biliary tract infection coincident with maternal methadone therapy.
    Pediatrics, 1971, Volume: 48, Issue:6

    Topics: Adult; Cholangitis; Cholecystitis; Female; Heroin; Humans; Infant, Newborn; Infant, Newborn, Disease

1971
The changing pattern of narcotic addiction in Britain--1959 to 1969.
    The International journal of the addictions, 1971, Volume: 6, Issue:1

    Topics: Adult; Age Factors; Amphetamine; Barbiturates; Cannabis; Cocaine; Drug and Narcotic Control; Heroin;

1971
The dimensions of drug dependence in the United Kingdom.
    The International journal of the addictions, 1971, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Barbiturates; Cannabis; Crime; Female; Geography; Heroi

1971
Methadone disks. Injectable-noninjectable tablets.
    Archives of general psychiatry, 1971, Volume: 25, Issue:6

    Topics: Administration, Oral; Heroin; Humans; Injections, Intravenous; Methadone; Morphine Dependence; Pharm

1971
A county health department's role in drug programs.
    HSMHA health reports, 1971, Volume: 86, Issue:12

    Topics: Attitude to Health; Community Health Services; Demography; Health Occupations; Heroin; Humans; Metha

1971
[Pharmacotherapy of morphine addiction].
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1971, Volume: 27, Issue:1

    Topics: Bridged-Ring Compounds; Humans; Methadone; Morphine; Morphine Dependence; Substance Withdrawal Syndr

1971
Narcotics and medical practice. Medical use of morphine and morphine-like drugs and management of persons dependent on them.
    JAMA, 1971, Oct-25, Volume: 218, Issue:4

    Topics: American Medical Association; Female; Health Education; Heroin; Humans; Legislation, Drug; Methadone

1971
Paean to Morpheus.
    JAMA, 1971, Oct-25, Volume: 218, Issue:4

    Topics: American Medical Association; Humans; Legislation, Drug; Methadone; Morphine Dependence; Substance W

1971
Methadone maintenance in heroin addiction.
    The American journal of nursing, 1970, Volume: 70, Issue:12

    Topics: Heroin; Humans; Methadone; Morphine Dependence; Psychiatric Nursing

1970
Methadone maintenance. Evolution of a day program.
    The American journal of nursing, 1970, Volume: 70, Issue:12

    Topics: Day Care, Medical; Humans; Methadone; Morphine Dependence

1970
Maintaining the methadone patient.
    Nursing outlook, 1970, Volume: 18, Issue:12

    Topics: Humans; Male; Methadone; Morphine Dependence; Public Health Nursing

1970
The role of the registered nurse in methadone maintenance programs.
    The Michigan nurse, 1971, Volume: 44, Issue:6

    Topics: Humans; Methadone; Michigan; Morphine Dependence; Nurses; Nursing

1971
Rehabilitation of heroin addicts after blockade with methadone.
    New York state journal of medicine, 1966, Aug-01, Volume: 66, Issue:15

    Topics: Female; Heroin; Humans; Male; Methadone; Morphine Dependence; Rehabilitation

1966
Statement by the New York Academy of Medicine.
    Bulletin of the New York Academy of Medicine, 1970, Volume: 46, Issue:1

    Topics: Academies and Institutes; Attitude of Health Personnel; Heroin; Humans; Methadone; Morphine Dependen

1970
Methadone and the private practitioner.
    The Journal of the Medical Society of New Jersey, 1971, Volume: 68, Issue:1

    Topics: Humans; Methadone; Morphine Dependence; Private Practice

1971
Methadone maintenance in hard-core criminal addicts. Economic effects.
    New York state journal of medicine, 1971, Jul-15, Volume: 71, Issue:14

    Topics: Adult; Chronic Disease; Crime; Economics; Heroin; Humans; Methadone; Middle Aged; Morphine Dependenc

1971
A case-note study of 134 out-patient drug addicts over a 17-month period.
    The British journal of addiction to alcohol and other drugs, 1971, Volume: 66, Issue:3

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Cocaine; Drug and Narcotic Control; Female; Heroin; Hum

1971
Methadone in the management of opiate addiction.
    The Medical letter on drugs and therapeutics, 1969, Nov-28, Volume: 11, Issue:24

    Topics: Heroin; Humans; Methadone; Morphine Dependence

1969
A quantitative method for the assessment of physical dependence on narcotic analgesics in mice.
    British journal of pharmacology, 1969, Volume: 37, Issue:2

    Topics: Animals; Humans; Meperidine; Methadone; Methods; Mice; Morphine Dependence; Motor Activity; Nalorphi

1969
Progress report on the methadone blockade. Treatment of heroin addicts in Portland.
    Northwest medicine, 1970, Volume: 69, Issue:3

    Topics: Heroin; Humans; Methadone; Morphine Dependence; Oregon

1970
Survey of a methadone maintenance treatment program.
    The American journal of psychiatry, 1970, Volume: 126, Issue:10

    Topics: Adult; Age Factors; Alcoholism; Barbiturates; Community Mental Health Services; Crime; Educational S

1970
Morphine dependent rats as a model for evaluating potential addiction liability of analgesic compounds.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 183, Issue:2

    Topics: Analgesics; Animals; Apomorphine; Azepines; Behavior, Animal; Codeine; Dextropropoxyphene; Diphenhyd

1970
Control programs for heroin addiction.
    JAMA, 1970, Feb-23, Volume: 211, Issue:8

    Topics: Attitude of Health Personnel; Heroin; Humans; Methadone; Morphine Dependence; Public Health; United

1970
Methadone and acetylmethadol maintenance.
    JAMA, 1970, Mar-16, Volume: 211, Issue:11

    Topics: Alcohols; Heroin; Humans; Methadone; Morphine Dependence

1970
A methadone program for addicts with chest disease.
    JAMA, 1970, Feb-09, Volume: 211, Issue:6

    Topics: Adult; Black People; Crime; Female; Follow-Up Studies; Hospitalization; Humans; Lung Diseases; Male;

1970
Methadone maintenance treatment program.
    Hospitals, 1970, Dec-01, Volume: 44, Issue:23

    Topics: Adult; Female; Heroin; Humans; Male; Methadone; Morphine Dependence

1970
Methadone maintenance treatment is successful for heroin addicts.
    Hospital management, 1970, Volume: 110, Issue:4

    Topics: Adolescent; Adult; Heroin; Hospitals, General; Humans; Methadone; Morphine Dependence; New York City

1970
Treatment of narcotic addicts in New York City.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adolescent; Community Mental Health Services; Female; Financing, Government; Heroin; Hospitals, Gene

1970
Research on methadone maintenance treatment.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Evaluation Studies as Topic; Heroin; Humans; Methadone; Morphine Dependence; New

1970
Further experience with methadone in the treatment of narcotics users.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adult; Ambulatory Care; Community Mental Health Services; Evaluation Studies as Topic; Female; Heroi

1970
Methadone maintenance programs in Minneapolis.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adult; Ambulatory Care; Community Mental Health Services; Female; Financing, Organized; Heroin; Hosp

1970
Methadone maintenance in St. Louis.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adult; Chromatography, Thin Layer; Community Mental Health Services; Counseling; Heroin; Hospitaliza

1970
The Man Alive program.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adult; Community Mental Health Services; Female; Heroin; Humans; Male; Maryland; Methadone; Morphine

1970
Two methods of utilizing methadone in the outpatient treatment of narcotic addicts.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adult; Aged; Community Mental Health Services; Counseling; Evaluation Studies as Topic; Female; Hero

1970
Low and high methadone maintenance in the out-patient treatment of the hard core heroin adict.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adult; Aged; Ambulatory Care; British Columbia; Community Mental Health Services; Crime; Criminal Ps

1970
The New Haven Methadone Maintenance Program.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adult; Amphetamine; Barbiturates; Cocaine; Community Health Services; Community Mental Health Servic

1970
Methadone in New Orleans: patients, problems and police.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Antisocial Personality Disorder; Community Mental Health Services; Criminal Psych

1970
Methadone related deaths in New York City.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adult; Alcoholism; Amphetamine; Barbiturates; Child, Preschool; Community Health Services; Evaluatio

1970
Methadone in Miami.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Community Mental Health Services; Crime; Drug Prescriptions; Emergency Service, H

1970
Blockade with methadone, cyclazocine, and naloxone.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Analgesics; Azocines; Cyclazocine; Evaluation Studies as Topic; Heroin; Hospitalization; Hospitals,

1970
Evaluation of methadone maintenance treatment program.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Age Factors; Alcoholism; Community Mental Health Services; Drug and Narcotic Cont

1970
Commentary on the Second National Conference on Methadone Treatment.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Humans; Methadone; Morphine Dependence; United States

1970
Second National Methadone Maintenance Conference. General discussion. Sunday afternoon October 26, 1969.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Humans; Methadone; Morphine Dependence; Substance-Related Disorders; United States

1970
Second National Methadone Maintenance Conference. Press conference.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Communication; Humans; Methadone; Morphine Dependence; Substance-Related Disorders; United States

1970
Secondary drug use among heroin users.
    The International journal of the addictions, 1970, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Aged; Amphetamine; Barbiturates; Cannabis; Cocaine; Crime; Educational Status; Et

1970
Low and high methadone maintenance in out-patient treatment of the heroin addict.
    The International journal of the addictions, 1970, Volume: 5, Issue:4

    Topics: Adult; Aged; British Columbia; Community Health Services; Criminal Psychology; Employment; Evaluatio

1970
Methadone maintenance: a comparison of two stabilization techniques.
    The International journal of the addictions, 1970, Volume: 5, Issue:4

    Topics: Adult; Community Health Services; Criminal Psychology; Employment; Evaluation Studies as Topic; Fema

1970
A guide for nurses on the use of methadone hydrochloride in drug dependence.
    Nursing times, 1971, Aug-05, Volume: 67, Issue:31

    Topics: Heroin; Humans; Methadone; Morphine Dependence

1971
Drug abuse treatment programs. Treatment now.
    Hospitals, 1971, Aug-01, Volume: 45, Issue:15

    Topics: Heroin; Hospitals; Humans; Methadone; Morphine Dependence; New York City

1971
Drug abuse treatment programs. Alternatives to methadone.
    Hospitals, 1971, Aug-01, Volume: 45, Issue:15

    Topics: Heroin; Humans; Methadone; Morphine Dependence; Therapeutic Community

1971
[Methadone treatment of heroin addicts].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1971, May-30, Volume: 91, Issue:15

    Topics: Humans; Methadone; Morphine Dependence

1971
Methadone, a new look at an old drug.
    Medico-legal bulletin, 1971, Volume: 20, Issue:8

    Topics: Administration, Oral; Analgesics; Drug and Narcotic Control; Heroin; Humans; Injections, Intravenous

1971
Narcotic antagonists in the treatment of opiate dependence.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:4

    Topics: Allyl Compounds; Carbamates; Cyclazocine; Ethers, Cyclic; Humans; Male; Methadone; Morphinans; Morph

1971
Pharmacology of narcotics and antagonists as related to drug abuse.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:4

    Topics: Codeine; Heroin; Humans; Levallorphan; Meperidine; Methadone; Morphine; Morphine Dependence; Nalorph

1971
Narcotic substitution therapy.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:4

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Heroin; Humans; Male; Methadone; Middle Aged; Mo

1971
Drug taking in adolescent girls: factors associated with the progression to narcotic use.
    British medical journal, 1971, Jun-12, Volume: 2, Issue:5762

    Topics: Adolescent; Amphetamine; Cannabis; Cocaine; Educational Status; Family; Female; Heroin; Humans; Juve

1971
The addiction cycle to narcotics in the rat and its relation to catecholamines.
    Biochemical pharmacology, 1968, Volume: 17, Issue:5

    Topics: Adrenal Glands; Animals; Body Weight; Brain; Drug Tolerance; Epinephrine; Female; Growth; Humans; Le

1968
Successful treatment of 750 criminal addicts.
    JAMA, 1968, Dec-16, Volume: 206, Issue:12

    Topics: Crime; Heroin; Humans; Male; Methadone; Morphine Dependence

1968
Progress report of evaluation of methadone maintenance treatment program as of March 31, 1968.
    JAMA, 1968, Dec-16, Volume: 206, Issue:12

    Topics: Adolescent; Adult; Crime; Ethnicity; Heroin; Humans; Male; Methadone; Middle Aged; Morphine Dependen

1968
Human behavior, medicine and social reform.
    The New England journal of medicine, 1969, Jun-19, Volume: 280, Issue:25

    Topics: Alcoholism; Antisocial Personality Disorder; Crime; Heroin; Humans; Medicine; Methadone; Morphine De

1969
[Treatment of drug addiction with narcotic blockade].
    Lakartidningen, 1966, Oct-26, Volume: 63, Issue:43

    Topics: Heroin; Humans; Methadone; Morphine Dependence

1966