Page last updated: 2024-10-30

methadone and Mononeuropathies

methadone has been researched along with Mononeuropathies in 3 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Mononeuropathies: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ISCHEMIA; traumatic injury; compression; CONNECTIVE TISSUE DISEASES; CUMULATIVE TRAUMA DISORDERS; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"Methadone was offered as a treatment option to consecutive cancer and noncancer patients with neuropathic pain."1.32Methadone in the treatment of neuropathic pain. ( Almahrezi, A; Gagnon, B; Schreier, G, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pelissier, T1
Laurido, C1
Kramer, V1
Hernández, A1
Paeile, C1
Gagnon, B1
Almahrezi, A1
Schreier, G1
Bulka, A1
Plesan, A1
Xu, XJ1
Wiesenfeld-Hallin, Z1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Influence of Aging on Perioperative Methadone Dosing[NCT04526236]Phase 460 participants (Actual)Interventional2019-09-03Completed
Methadone for 'Adenocarcinopathic' Pain Treatment: Methadone vs. Morphine Vanguard RCT[NCT05325164]Phase 30 participants (Actual)Interventional2022-09-30Withdrawn (stopped due to Trial not started; change in Sponsor and Principal Investigator, trial to be registered again by new Sponsor/Investigator if it is started.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for methadone and Mononeuropathies

ArticleYear
Antinociceptive interactions of ketamine with morphine or methadone in mononeuropathic rats.
    European journal of pharmacology, 2003, Sep-05, Volume: 477, Issue:1

    Topics: Analgesics; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therap

2003
Methadone in the treatment of neuropathic pain.
    Pain research & management, 2003,Fall, Volume: 8, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Methadone; Middle Aged; Mononeuropathies; Pain

2003
Methadone in the treatment of neuropathic pain.
    Pain research & management, 2003,Fall, Volume: 8, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Methadone; Middle Aged; Mononeuropathies; Pain

2003
Methadone in the treatment of neuropathic pain.
    Pain research & management, 2003,Fall, Volume: 8, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Methadone; Middle Aged; Mononeuropathies; Pain

2003
Methadone in the treatment of neuropathic pain.
    Pain research & management, 2003,Fall, Volume: 8, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Methadone; Middle Aged; Mononeuropathies; Pain

2003
Reduced tolerance to the anti-hyperalgesic effect of methadone in comparison to morphine in a rat model of mononeuropathy.
    Pain, 2002, Volume: 95, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Drug Tolerance; Hyperalgesia; Male; Methadone;

2002