Page last updated: 2024-10-30

methadone and Marijuana Abuse

methadone has been researched along with Marijuana Abuse in 46 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Marijuana Abuse: Use of marijuana associated with abnormal psychological, social, and or occupational functioning.

Research Excerpts

ExcerptRelevanceReference
"Depression is one of the most common psychiatric conditions in men."5.39Depression in male patients on methadone maintenance therapy. ( Baharudin, A; Ibrahim, N; Mislan, N; Nik Jaafar, NR; Sidi, H, 2013)
"  Methadone use in pregnancy has been associated with adverse perinatal outcomes and neonatal abstinence syndrome (NAS)."3.78Methadone and perinatal outcomes: a prospective cohort study. ( Carmody, D; Clarke, T; Cleary, BJ; Eogan, M; Fahey, T; Gallagher, PJ; Gleeson, J; McDermott, C; Murphy, DJ; O'Connell, MP; O'Sullivan, A; White, MJ, 2012)
"This paper describes patterns of drug use such as choice of drug, other substances abused, and route of administration in 174 women who reported methamphetamine, cocaine, heroin, or "Ts and blues" abuse during pregnancy."3.68Patterns of multiple substance abuse during pregnancy: implications for mother and fetus. ( Gilstrap, LD; Johnston, WL; Little, BB; Snell, LM, 1990)
"To test if polysubstance use profiles and drug-related outcomes differ between those receiving and not receiving opioid substitution therapies (OST) among people who inject drugs (PWID)."1.43Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies. ( Alati, R; Betts, KS; Burns, L; Chan, G; Dietze, P; McIlwraith, F; Whittaker, E, 2016)
"Depression is one of the most common psychiatric conditions in men."1.39Depression in male patients on methadone maintenance therapy. ( Baharudin, A; Ibrahim, N; Mislan, N; Nik Jaafar, NR; Sidi, H, 2013)
"Recent clinical studies suggest that substance use may be associated with an acceleration of the ageing process, possibly related to a deficit of stem cell number or function."1.35An intriguing association between dental and mental pathology in addicted and control subjects: a cross-sectional survey. ( Reece, AS, 2008)
"Although it is said that drug addiction is associated with poor dental health, there is little research in this area."1.34Dentition of addiction in Queensland: poor dental status and major contributing drugs. ( Reece, AS, 2007)
"In the national Drug Abuse Treatment Outcome Studies (DATOS), many clients in outpatient methadone treatment (OMT) and outpatient drug-free (ODF) modalities were admitted with multiple sex and needle-risk behaviors, but they reduced these risks significantly during treatment."1.30HIV risk reduction in outpatient drug abuse treatment: individual and geographic differences. ( Broome, KM; Joe, GW; Simpson, DD, 1999)
" In particular, studies of retention, counselor characteristics, program policies and goals, the nature and extent of services received by clients, the context in which treatment is administered, methadone dosage levels, and other such variables are reviewed."1.27Drug abuse treatment process: a review of the literature. ( Allison, M; Hubbard, RL, 1985)
"There are multiple causes for intrauterine growth retardation but one etiology proposed is maternal drugs."1.27Maternal drug therapy: effect on fetal and neonatal growth and neurobehavior. ( Hill, RM; Tennyson, LM, 1986)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19908 (17.39)18.7374
1990's10 (21.74)18.2507
2000's15 (32.61)29.6817
2010's11 (23.91)24.3611
2020's2 (4.35)2.80

Authors

AuthorsStudies
Rodríguez Mega, E1
Mehtani, NJ1
Ristau, JT1
Snyder, H1
Surlyn, C1
Eveland, J1
Smith-Bernardin, S1
Knight, KR1
Grant, TM1
Graham, JC1
Carlini, BH1
Ernst, CC1
Brown, NN1
Baharudin, A1
Mislan, N1
Ibrahim, N1
Sidi, H1
Nik Jaafar, NR1
Richert, T1
Johnson, B1
Bonnet, U1
Stratmann, U1
Isbruch, K1
Betts, KS1
Chan, G1
McIlwraith, F1
Dietze, P1
Whittaker, E1
Burns, L1
Alati, R1
Zielinski, L1
Bhatt, M1
Eisen, RB1
Perera, S1
Bhatnagar, N1
MacKillop, J1
Steiner, M1
McDermid Vaz, S1
Thabane, L1
Samaan, Z1
Eksborg, S1
Rajs, J1
Reece, AS3
Simkin, DR1
Grenoble, S1
van Holst, RJ1
Schilt, T1
Cleary, BJ1
Eogan, M1
O'Connell, MP1
Fahey, T1
Gallagher, PJ1
Clarke, T1
White, MJ1
McDermott, C1
O'Sullivan, A1
Carmody, D1
Gleeson, J1
Murphy, DJ1
Piralishvili, G1
Gamkrelidze, I1
Nikolaishvili, N1
Chavchanidze, M1
Seivewright, N1
Epstein, DH2
Preston, KL2
Nixon, LN1
Ventegodt, S1
Merrick, J1
Verdejo, A1
Toribio, I1
Orozco, C1
Puente, KL1
Pérez-García, M2
Petry, NM1
Kolodner, KB1
Li, R1
Peirce, JM1
Roll, JM1
Stitzer, ML1
Hamilton, JA1
Trafton, JA1
Minkel, J1
Humphreys, K1
Ghitza, UE1
Nava, F1
Manzato, E1
Lucchini, A1
Zullino, DF1
Krenz, S1
Eap, CB2
Benguettat, D1
Khan, R1
Besson, J1
Khazaal, Y1
Montagrin, Y1
Rihs-Middel, M1
Simon, O1
Tissot, H1
Tomei, A1
Zumwald, C1
Zullino, D1
Aguilar de Arcos, F1
Verdejo-García, A1
Ceverino, A1
Montañez-Pareja, M1
López-Juárez, E1
Sánchez-Barrera, M1
López-Jiménez, A1
Jasinski, DR1
Boren, JJ1
Henningfield, JE1
Johnson, RE1
Lange, WR1
Lukas, SE1
Ginzburg, HM1
Allison, M2
Hubbard, RL2
Simpson, DD2
Joe, GW2
Bracy, SA1
Compton, WM1
Lamb, RJ1
Fletcher, BW1
Ladewig, D1
Behringer, HJ1
Brown, LS1
Alterman, AI1
Rutherford, MJ1
Cacciola, JS1
Zaballero, AR1
Bell, J1
Mattick, R1
Hay, A1
Chan, J1
Hall, W1
Frosch, DL1
Shoptaw, S1
Jarvik, ME1
Rawson, RA1
Ling, W1
Brewer, DD1
Fleming, CB1
Haggerty, KP1
Catalano, RF1
Calsyn, DA1
Saxon, AJ1
Eyler, FD1
Behnke, M1
Broome, KM1
Little, BB1
Snell, LM1
Gilstrap, LD1
Johnston, WL1
Rosen, TS1
Johnson, HL1
DuPont, RL1
Saylor, KE1
Ventura, MT1
Serlenga, E1
Antonaci, S1
Jirillo, E1
Bonomo, L1
Hill, RM1
Tennyson, LM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Fetal Exposure to Cannabinoids: Exposure, Methylation and Neurodevelopmental Effects[NCT04422600]72 participants (Actual)Observational [Patient Registry]2020-02-26Completed
[NCT00292123]Phase 1200 participants (Actual)Interventional1999-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for methadone and Marijuana Abuse

ArticleYear
Pharmacotherapies for adolescent substance use disorders.
    Child and adolescent psychiatric clinics of North America, 2010, Volume: 19, Issue:3

    Topics: Adolescent; Alcohol Deterrents; Alcoholism; Cocaine-Related Disorders; Disulfiram; Humans; Marijuana

2010
Drug-related decrease in neuropsychological functions of abstinent drug users.
    Current drug abuse reviews, 2011, Volume: 4, Issue:1

    Topics: Alcoholism; Amphetamine-Related Disorders; Cannabis; Central Nervous System Stimulants; Cocaine; Coc

2011
Does cannabis use predict poor outcome for heroin-dependent patients on maintenance treatment? Past findings and more evidence against.
    Addiction (Abingdon, England), 2003, Volume: 98, Issue:3

    Topics: Adult; Analgesics, Opioid; Analysis of Variance; Cannabinoids; Chi-Square Distribution; Clinical Tri

2003
[Addiction].
    Revue medicale suisse, 2008, Jan-09, Volume: 4, Issue:139

    Topics: Gambling; Heart Diseases; Humans; Internet; Marijuana Abuse; Methadone; Substance-Related Disorders

2008
Early development of infants exposed to drugs prenatally.
    Clinics in perinatology, 1999, Volume: 26, Issue:1

    Topics: Alcoholism; Child Abuse; Child Development; Child, Preschool; Cocaine; Cocaine-Related Disorders; Et

1999

Trials

3 trials available for methadone and Marijuana Abuse

ArticleYear
Prize-based contingency management does not increase gambling.
    Drug and alcohol dependence, 2006, Jul-27, Volume: 83, Issue:3

    Topics: Adult; Alcoholism; Ambulatory Care; Amphetamine-Related Disorders; Central Nervous System Stimulants

2006
Nonreporting of cannabis use: Predictors and relationship to treatment outcome in methadone maintained patients.
    Addictive behaviors, 2007, Volume: 32, Issue:5

    Topics: Administration, Oral; Adult; Analgesics, Opioid; Behavior Therapy; Black or African American; Cocain

2007
Dysregulation of emotional response in current and abstinent heroin users: negative heightening and positive blunting.
    Psychopharmacology, 2008, Volume: 198, Issue:2

    Topics: Adult; Alcoholism; Arousal; Cocaine-Related Disorders; Emotions; Female; Heroin Dependence; Humans;

2008

Other Studies

38 other studies available for methadone and Marijuana Abuse

ArticleYear
The psychiatrist at the centre of the opioid crisis.
    Nature, 2020, Volume: 580, Issue:7802

    Topics: Alcoholism; Cocaine-Related Disorders; Dopamine; Drug Overdose; Heroin Dependence; History, 20th Cen

2020
COVID-19: A catalyst for change in telehealth service delivery for opioid use disorder management.
    Substance abuse, 2021, Volume: 42, Issue:2

    Topics: Adult; Alcoholism; Analgesics, Opioid; Buprenorphine; COVID-19; Delivery of Health Care; Feasibility

2021
Use of Marijuana and Other Substances Among Pregnant and Parenting Women With Substance Use Disorders: Changes in Washington State After Marijuana Legalization.
    Journal of studies on alcohol and drugs, 2018, Volume: 79, Issue:1

    Topics: Adult; Amphetamines; Female; Humans; Legislation, Drug; Marijuana Abuse; Marijuana Smoking; Methadon

2018
Depression in male patients on methadone maintenance therapy.
    Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists, 2013, Volume: 5 Suppl 1

    Topics: Adult; Cross-Sectional Studies; Depression; Educational Status; Humans; Interview, Psychological; Ma

2013
Illicit use of methadone and buprenorphine among adolescents and young adults in Sweden.
    Harm reduction journal, 2013, Oct-18, Volume: 10

    Topics: Adolescent; Adult; Attitude of Health Personnel; Buprenorphine; Data Interpretation, Statistical; Da

2013
[No opiates against cannabis hyperemesis syndrome].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:8

    Topics: Adult; Antiemetics; Dronabinol; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combina

2014
Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies.
    Addiction (Abingdon, England), 2016, Volume: 111, Issue:7

    Topics: Abscess; Adolescent; Adult; Alcoholism; Amphetamine-Related Disorders; Analgesics, Opioid; Australia

2016
Association between cannabis use and treatment outcomes in patients receiving methadone maintenance treatment: a systematic review protocol.
    Systematic reviews, 2016, 08-16, Volume: 5, Issue:1

    Topics: Analgesics, Opioid; Cannabis; Humans; Marijuana Abuse; Marijuana Smoking; Methadone; Opiate Substitu

2016
Causes and manners of death among users of heroin, methadone, amphetamine, and cannabis in relation to postmortem chemical tests for illegal drugs.
    Substance use & misuse, 2008, Volume: 43, Issue:10

    Topics: Adolescent; Adult; Aged; Amphetamine; Amphetamine-Related Disorders; Cause of Death; Diagnosis; Fema

2008
An intriguing association between dental and mental pathology in addicted and control subjects: a cross-sectional survey.
    British dental journal, 2008, Dec-13, Volume: 205, Issue:11

    Topics: Adolescent; Adult; Aggression; Aging; Alcohol Drinking; Amphetamine-Related Disorders; Anxiety; Atte

2008
Differing age related trajectories of dysfunction in several organ systems in opiate dependence.
    Aging clinical and experimental research, 2012, Volume: 24, Issue:1

    Topics: Adult; Aged; Aging; Aging, Premature; Analgesics, Opioid; Disease Progression; Female; Hair Color; H

2012
Methadone and perinatal outcomes: a prospective cohort study.
    Addiction (Abingdon, England), 2012, Volume: 107, Issue:8

    Topics: Adult; Benzodiazepines; Dose-Response Relationship, Drug; Female; Heroin Dependence; Humans; Infant,

2012
Needs assessment and treatment compliance at state opioid substitution treatment programes in Georgia.
    Georgian medical news, 2013, Issue:214

    Topics: Adult; Aged; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Female; Georgia (Republic); Go

2013
Methadone treatment outcomes appear mainly unaffected by cannabis use.
    Addiction (Abingdon, England), 2003, Volume: 98, Issue:3

    Topics: Analgesics, Opioid; Cocaine-Related Disorders; Heroin Dependence; Humans; Marijuana Abuse; Methadone

2003
Cannabis use and treatment outcome in methadone maintenance.
    Addiction (Abingdon, England), 2003, Volume: 98, Issue:9

    Topics: Analgesics, Opioid; Cannabinoids; Heroin Dependence; Humans; Marijuana Abuse; Methadone; Treatment O

2003
Psychoactive drugs and quality of life.
    TheScientificWorldJournal, 2003, Aug-18, Volume: 3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amphetamines; Cocaine; Cohort Studies; Data Collection;

2003
Neuropsychological functioning in methadone maintenance patients versus abstinent heroin abusers.
    Drug and alcohol dependence, 2005, Jun-01, Volume: 78, Issue:3

    Topics: Adult; Alcoholism; Cocaine-Related Disorders; Cognition Disorders; Female; Heroin Dependence; Humans

2005
Opioid substitution treatment reduces substance use equivalently in patients with and without posttraumatic stress disorder.
    Journal of studies on alcohol, 2006, Volume: 67, Issue:2

    Topics: Adult; Aged; Alcoholism; Cocaine-Related Disorders; Combat Disorders; Comorbidity; Female; Follow-Up

2006
Chronic cannabis use does not affect the normalization of hypothalamic-pituitary-adrenal (HPA) axis induced by methadone in heroin addicts.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Jun-30, Volume: 31, Issue:5

    Topics: Adrenocorticotropic Hormone; Adult; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Female; He

2007
Dentition of addiction in Queensland: poor dental status and major contributing drugs.
    Australian dental journal, 2007, Volume: 52, Issue:2

    Topics: Adult; Age Factors; Alcohol-Related Disorders; Amphetamine-Related Disorders; Cross-Sectional Studie

2007
Over- and underreporting of recent drug use in subjects entering an inpatient detoxification unit.
    European journal of medical research, 2008, Jan-23, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Benzodiazepines; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; In

2008
Progress report from the NIDA Addiction Research Center, Baltimore, Maryland.
    NIDA research monograph, 1984, Volume: 49

    Topics: Anti-Anxiety Agents; Buprenorphine; Double-Blind Method; Dronabinol; Drug Synergism; Heroin Dependen

1984
Depressive symptoms in drug abuse treatment clients: correlates, treatment, and changes.
    NIDA research monograph, 1984, Volume: 49

    Topics: Adult; Age Factors; Alcoholism; Ambulatory Care; Depressive Disorder; Female; Heroin Dependence; Hum

1984
Six-year follow-up of opioid addicts after admission to treatment.
    Archives of general psychiatry, 1982, Volume: 39, Issue:11

    Topics: Adult; Alcoholism; Ambulatory Care; Community Mental Health Services; Female; Follow-Up Studies; Her

1982
Results of the NIDA treatment demonstration grants' cocaine workgroup: characteristics of cocaine users and HIV risk behaviors.
    Drug and alcohol dependence, 1995, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Cocaine; Comorbidity; Ethnicity; Female; Health Behavior; HIV Infections; Humans;

1995
[A case from practice (238). Benzodiazepine withdrawal delirium in a multidrug addict].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1994, Jan-11, Volume: 83, Issue:2

    Topics: Adult; Benzodiazepines; Diagnosis, Differential; Humans; Male; Marijuana Abuse; Methadone; Substance

1994
Addiction Severity Index scores of four racial/ethnic and gender groups of methadone maintenance patients.
    Journal of substance abuse, 1993, Volume: 5, Issue:3

    Topics: Adult; Alcoholism; Black or African American; Cocaine; Comorbidity; Cross-Cultural Comparison; Cross

1993
Methadone maintenance and drug-related crime.
    Journal of substance abuse, 1997, Volume: 9

    Topics: Adult; Antisocial Personality Disorder; Attitude of Health Personnel; Crime; Female; Heroin Dependen

1997
Interest in smoking cessation among methadone maintained outpatients.
    Journal of addictive diseases, 1998, Volume: 17, Issue:2

    Topics: Adult; Ambulatory Care; Analgesics, Opioid; Female; Humans; Male; Marijuana Abuse; Methadone; Motiva

1998
Drug use predictors of partner violence in opiate-dependent women.
    Violence and victims, 1998,Summer, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Alcohol Drinking; Battered Women; Child; Child, Preschool; Cocaine-Related Disord

1998
An innovative approach to reducing cannabis use in a subset of methadone maintenance clients.
    Drug and alcohol dependence, 1999, Jan-07, Volume: 53, Issue:2

    Topics: Adult; Humans; Marijuana Abuse; Methadone; Middle Aged; Narcotics; Predictive Value of Tests; Substa

1999
HIV risk reduction in outpatient drug abuse treatment: individual and geographic differences.
    AIDS education and prevention : official publication of the International Society for AIDS Education, 1999, Volume: 11, Issue:4

    Topics: Adult; Alcoholism; Antisocial Personality Disorder; Cities; Cocaine-Related Disorders; Female; HIV I

1999
Patterns of multiple substance abuse during pregnancy: implications for mother and fetus.
    Southern medical journal, 1990, Volume: 83, Issue:5

    Topics: Adolescent; Adult; Age Factors; Alcoholism; Cocaine; Female; Fetal Diseases; Heroin; Humans; Marijua

1990
Drug-addicted mothers, their infants, and SIDS.
    Annals of the New York Academy of Sciences, 1988, Volume: 533

    Topics: Adult; Alcohol Drinking; Cocaine; Developmental Disabilities; Female; Heroin Dependence; Humans; Inf

1988
Marijuana and benzodiazepines in patients receiving methadone treatment.
    JAMA, 1989, Jun-16, Volume: 261, Issue:23

    Topics: Anti-Anxiety Agents; Benzodiazepines; Humans; Marijuana Abuse; Methadone; Substance-Related Disorder

1989
Drug abuse treatment process: a review of the literature.
    The International journal of the addictions, 1985, Volume: 20, Issue:9

    Topics: Aftercare; Ambulatory Care; Combined Modality Therapy; Community Mental Health Services; Counseling;

1985
[Cell-mediated immunity in drug addicts: interaction of opiates and naloxone on natural cytotoxic activity and immune-mediated reactions of phagocytes].
    Recenti progressi in medicina, 1988, Volume: 79, Issue:6

    Topics: Adult; Chemotaxis, Leukocyte; Granulocytes; Heroin Dependence; Humans; Immunity, Cellular; Immunity,

1988
Maternal drug therapy: effect on fetal and neonatal growth and neurobehavior.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Aminopterin; Amphetamines; Animals; Anticoagulants; Anticonvulsants; Antihypertensive Agents; Birth

1986