Page last updated: 2024-10-30

methadone and Lung Diseases

methadone has been researched along with Lung Diseases in 16 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Lung Diseases: Pathological processes involving any part of the LUNG.

Research Excerpts

ExcerptRelevanceReference
"A program of detoxification of heroin addicts by the use of oral methadone produced a series of patients who developed pulmonary granulomatous mass lesions as the result of the intravenous use of the oral form of the drug."3.66Conglomerate pulmonary disease: a form of talcosis in intravenous methadone abusers. ( Nidecker, AC; Sieniewicz, DJ, 1980)
"Despite discontinuation of the drug abuse, all developed severe respiratory disability and three died from their disease."1.28Long-term follow-up of drug abusers with intravenous talcosis. ( Cote, G; Fraser, RS; Paré, JP, 1989)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199014 (87.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pilgrim, JL1
McDonough, M1
Drummer, OH1
Cousins, G1
Teljeur, C1
Motterlini, N1
McCowan, C1
Dimitrov, BD1
Fahey, T1
Sieniewicz, DJ1
Nidecker, AC1
Rubenstein, RB1
Spira, I1
Wolff, WI1
Paré, JA1
Fraser, RG1
Hogg, JC1
Howlett, JG1
Murphy, SB1
Arnett, EN1
Battle, WE1
Russo, JV1
Roberts, WC1
Byers, JM1
Soin, JS1
Fisher, RS1
Hutchins, GM1
Budakov, B1
Paré, JP1
Cote, G1
Fraser, RS1
Rosenow, EC1
Lewit, T1
Saba, GP1
James, AE1
Johnson, BA1
Stitik, FP1
Burns, B1
Thornton, WE1
Thornton, BP1
Genereux, GP1
Emson, HE1
Hoffman, L1
Bainborough, AR1
Jericho, KW1

Reviews

2 reviews available for methadone and Lung Diseases

ArticleYear
The spectrum of drug-induced pulmonary disease.
    Annals of internal medicine, 1972, Volume: 77, Issue:6

    Topics: Adrenal Cortex Hormones; Aerosols; Analgesics; Aspirin; Autonomic Agents; Bleomycin; Busulfan; Contr

1972
[Pulmonary diseases due to drugs. II].
    Harefuah, 1974, Jun-16, Volume: 86, Issue:12

    Topics: Amines; Amitriptyline; Beclomethasone; Drug-Related Side Effects and Adverse Reactions; Heroin; Huma

1974

Other Studies

14 other studies available for methadone and Lung Diseases

ArticleYear
A review of methadone deaths between 2001 and 2005 in Victoria, Australia.
    Forensic science international, 2013, Mar-10, Volume: 226, Issue:1-3

    Topics: Adolescent; Adult; Australia; Cause of Death; Chronic Pain; Dose-Response Relationship, Drug; Female

2013
Risk of drug-related mortality during periods of transition in methadone maintenance treatment: a cohort study.
    Journal of substance abuse treatment, 2011, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Cohort Studies; Databases, Factual; Female; Humans; Lung Diseases; Male; Medical

2011
Conglomerate pulmonary disease: a form of talcosis in intravenous methadone abusers.
    AJR. American journal of roentgenology, 1980, Volume: 135, Issue:4

    Topics: Adult; Female; Granuloma; Humans; Injections, Intravenous; Lung Diseases; Male; Methadone; Middle Ag

1980
Management of surgical problems in patients on methadone maintenance.
    American journal of surgery, 1976, Volume: 131, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Cocaine; Female; Heroin Dependence; Humans; Hydromorph

1976
Pulmonary 'mainline' granulomatosis: talcosis of intravenous methadone abuse.
    Medicine, 1979, Volume: 58, Issue:3

    Topics: Adult; Female; Granuloma; Humans; Injections, Intravenous; Lung; Lung Diseases; Male; Methadone; Rad

1979
Intravenous injection of talc-containing drugs intended for oral use. A cause of pulmonary granulomatosis and pulmonary hypertension.
    The American journal of medicine, 1976, May-10, Volume: 60, Issue:5

    Topics: Adolescent; Adult; Dyspnea; Female; Granuloma; Heroin Dependence; Humans; Hypertension, Pulmonary; I

1976
Acute pulmonary alveolitis in narcotics abuse.
    Archives of pathology, 1975, Volume: 99, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Angiography; Cocaine; Female; Foreign Bodies; Foreign-Body Reactio

1975
Morphogenesis of lung lesions in experimental intravenous administrations of drugs.
    Acta medicinae legalis et socialis, 1989, Volume: 39, Issue:2

    Topics: Animals; Granuloma, Giant Cell; Injections, Intravenous; Lung; Lung Diseases; Methadone; Pulmonary E

1989
Long-term follow-up of drug abusers with intravenous talcosis.
    The American review of respiratory disease, 1989, Volume: 139, Issue:1

    Topics: Adult; Follow-Up Studies; Humans; Injections, Intravenous; Lung; Lung Diseases; Lung Volume Measurem

1989
Pulmonary complications of narcotic abuse.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1974, Volume: 122, Issue:4

    Topics: Barbiturates; Heroin Dependence; Humans; Lung Diseases; Methadone; Pneumonia, Aspiration; Pulmonary

1974
Adverse reactions to heroin use.
    Southern medical journal, 1974, Volume: 67, Issue:6

    Topics: Abscess; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Chromosomes; Endocarditis; Femal

1974
Talc granulomatosis and angiothrombotic pulmonary hypertension in drug addicts.
    Journal of the Canadian Association of Radiologists, 1974, Volume: 25, Issue:2

    Topics: Adult; Capillaries; Capsules; Foreign Bodies; Granuloma; Heart; Humans; Hypertension, Pulmonary; Inj

1974
A methadone program for addicts with chest disease.
    JAMA, 1970, Feb-09, Volume: 211, Issue:6

    Topics: Adult; Black People; Crime; Female; Follow-Up Studies; Hospitalization; Humans; Lung Diseases; Male;

1970
Cor pulmonale secondary to talc granulomata in the lungs of a drug addict.
    Canadian Medical Association journal, 1970, Dec-05, Volume: 103, Issue:12

    Topics: Adult; Animals; Autopsy; Female; Granuloma; Guinea Pigs; Humans; Injections, Intravenous; Lung; Lung

1970