methadone has been researched along with Liver Diseases in 21 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For methadone, there was a non-significant 41 % increased advanced fibrosis risk in Whites and 51 % reduced risk in AA." | 5.38 | Finasteride and methadone use and risk of advanced hepatitis C related liver disease. ( El-Serag, HB; Hashmi, A; Kuzniarek, J; Ramsey, DJ; Tavakoli-Tabasi, S; White, DL, 2012) |
| " Examples of situations that characterise these special populations are: co-infection with hepatitis virus B and/or C, pregnancy, lipodystrophy, cardiovascular risk, renal failure, treatment of children and adolescents, immigrant health care, and the management of patients receiving methadone replacement therapy, among others." | 4.84 | [Utility of atazanavir in special populations]. ( Antela López, A, 2008) |
| "Methadone hydrochloride is a mu-opioid agonist that has been used for the treatment of pain and for the management and maintenance of opioid withdrawal for over 50 years." | 4.81 | Clinical use of methadone. ( Goode, JV; Layson-Wolf, C; Small, RE, 2002) |
| " Among 42 active heroin users or former heroin addicts maintained on methadone, 79% were heavy alcohol abusers." | 3.65 | The spectrum and causes of liver diseases in narcotic addicts. ( Gelb, AM; Mildvan, D; Stenger, RJ, 1977) |
| "For methadone, there was a non-significant 41 % increased advanced fibrosis risk in Whites and 51 % reduced risk in AA." | 1.38 | Finasteride and methadone use and risk of advanced hepatitis C related liver disease. ( El-Serag, HB; Hashmi, A; Kuzniarek, J; Ramsey, DJ; Tavakoli-Tabasi, S; White, DL, 2012) |
| "2." | 1.38 | Trekking new ground: overcoming medical and social impediments for extended criteria liver transplant recipients. ( McCaughan, GW, 2012) |
| " The data suggest that the maintenance dosage of methadone need not be changed in stable chronic liver disease." | 1.26 | Methadone disposition in patients with chronic liver disease. ( Fanizza, AM; Gelb, AM; Kreek, MJ; Novick, DM; Stenger, RJ; Yancovitz, SR, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (57.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grassi, A | 1 |
| Ballardini, G | 1 |
| Robaeys, G | 1 |
| Nevens, F | 1 |
| Stärkel, P | 1 |
| Colle, I | 1 |
| Van Eyken, P | 1 |
| Bruckers, L | 1 |
| Van Ranst, M | 1 |
| Buntinx, F | 1 |
| Müller, MC | 1 |
| Pichler, M | 1 |
| Martin, G | 1 |
| Plörer, D | 1 |
| Winter, C | 1 |
| Pogarell, O | 1 |
| Bogner, JR | 1 |
| Antela López, A | 1 |
| Murnion, B | 1 |
| White, DL | 1 |
| Hashmi, A | 1 |
| Ramsey, DJ | 1 |
| Kuzniarek, J | 1 |
| Tavakoli-Tabasi, S | 1 |
| El-Serag, HB | 1 |
| McCaughan, GW | 1 |
| Layson-Wolf, C | 1 |
| Goode, JV | 1 |
| Small, RE | 1 |
| Novick, DM | 1 |
| Kreek, MJ | 5 |
| Fanizza, AM | 1 |
| Yancovitz, SR | 1 |
| Gelb, AM | 2 |
| Stenger, RJ | 2 |
| Bencsath, FA | 1 |
| Field, FH | 1 |
| Habrat, B | 1 |
| Chmielewska, K | 1 |
| Baran-Furga, H | 1 |
| Rubenstein, RB | 1 |
| Spira, I | 1 |
| Wolff, WI | 1 |
| Webster, IW | 1 |
| Waddy, N | 1 |
| Jenkins, LV | 1 |
| Lai, LY | 1 |
| Mildvan, D | 1 |
| Khuri, E | 1 |
| Fahey, L | 1 |
| Miescher, A | 1 |
| Arns, P | 1 |
| Spagnoli, D | 1 |
| Craig, J | 1 |
| Millman, R | 1 |
| Harte, EH | 1 |
| Brown, SM | 1 |
| Stimmel, B | 2 |
| Taub, RN | 1 |
| Kochwa, S | 1 |
| Rosenfield, RE | 1 |
| Cushman, P | 1 |
| Bihari, B | 1 |
| Spiera, H | 1 |
| Oreskes, I | 1 |
4 reviews available for methadone and Liver Diseases
| Article | Year |
|---|---|
[Utility of atazanavir in special populations].
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Cardi | 2008 |
Management of opioid substitution therapy during medical intervention.
Topics: Analgesics; Australia; Buprenorphine; Comorbidity; Drug Interactions; Female; Humans; Liver Diseases | 2012 |
Clinical use of methadone.
Topics: Analgesics, Opioid; Biological Availability; Dosage Forms; Drug Administration Schedule; Drug Intera | 2002 |
Medical complications in methadone patients.
Topics: Alcoholism; Analgesics; Anesthetics; Blood Proteins; Chronic Disease; Drug Interactions; Ethanol; Ho | 1978 |
17 other studies available for methadone and Liver Diseases
| Article | Year |
|---|---|
Hepatitis C in injection drug users: It is time to treat.
Topics: Antiviral Agents; Buprenorphine; Drug Users; Hepatitis C; Humans; Interdisciplinary Communication; L | 2017 |
Previous intravenous substance use and outcome of liver transplantation in patients with chronic hepatitis C infection.
Topics: Biopsy; Female; Graft Rejection; Graft Survival; Hepatitis C, Chronic; Humans; Immunosuppressive Age | 2009 |
[Burden of disease and level of patient's medical care in substitution treatment for opiates].
Topics: Adult; Asthma; Comorbidity; Cooperative Behavior; Cost of Illness; Cross-Sectional Studies; Female; | 2009 |
Finasteride and methadone use and risk of advanced hepatitis C related liver disease.
Topics: 5-alpha Reductase Inhibitors; Adult; Aged; Cross-Sectional Studies; Finasteride; Hepatitis C; Humans | 2012 |
Trekking new ground: overcoming medical and social impediments for extended criteria liver transplant recipients.
Topics: Comorbidity; Contraindications; Coronary Artery Disease; Humans; Liver Diseases; Liver Transplantati | 2012 |
Methadone disposition in patients with chronic liver disease.
Topics: Administration, Oral; Adult; Alcoholism; Chronic Disease; Dose-Response Relationship, Drug; Female; | 1981 |
Effects of liver disease on urinary excretion of methadone and metabolites in maintenance patients: quantitation by direct probe chemical ionization mass spectrometry.
Topics: Chronic Disease; Female; Heroin Dependence; Humans; Liver Diseases; Male; Mass Spectrometry; Methado | 1980 |
[Health status of individuals dependent on opiates before and after a year of treatment in a methadone maintenance program].
Topics: Adult; Female; Health Status; Humans; Infections; Liver Diseases; Male; Methadone; Opioid-Related Di | 2001 |
Management of surgical problems in patients on methadone maintenance.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Cocaine; Female; Heroin Dependence; Humans; Hydromorph | 1976 |
Health status of a group of narcotic addicts in a methadone treatment programme.
Topics: Adult; Alcohol Drinking; Drug Prescriptions; Family Characteristics; Female; Health Surveys; Humans; | 1977 |
The spectrum and causes of liver diseases in narcotic addicts.
Topics: Acute Disease; Alcoholism; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Chronic Disease; | 1977 |
Long-term followup studies of the medical status of adolescent former heroin addicts in chronic methadone maintenance treatment: liver disease and immune status.
Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Blood Proteins; Follow-Up Studies; He | 1986 |
Immunologic dysfunction in heroin addicts.
Topics: Adult; Antibody Formation; Concanavalin A; Deoxyuridine; False Positive Reactions; Follow-Up Studies | 1974 |
Persistent increased immunoglobulin M in treated narcotic addition. Association with liver disease and continuing heroin use.
Topics: Adult; Female; Heroin; Humans; Immunoglobulin M; Liver Diseases; Male; Methadone; Substance-Related | 1973 |
Alcoholism in M.M.T.P. patients: etiological factors and treatment approaches.
Topics: Alcoholism; Chronic Disease; Family Therapy; Heroin Dependence; Humans; Liver Diseases; Methadone; N | 1973 |
Physiologic implications of methadone treatment.
Topics: Adult; Alcoholism; Drug Tolerance; Electrocardiography; Female; Heroin Dependence; Hospitalization; | 1973 |
Rheumatoid factor activity in heroin addicts on methadone maintenance.
Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; False Positive R | 1974 |