methadone has been researched along with Liver Cirrhosis in 19 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Follow-up images showed resolution of hepatopulmonary syndrome following methadone withdrawal although there had been no improvement in his liver disease." | 7.77 | Resolution of hepatopulmonary syndrome after methadone withdrawal as demonstrated by right to left shunt study. ( Allman, KC; Kitzing, B; Torzillo, PJ, 2011) |
| " We report the case of a 50-year-old man with hepatitis C cirrhosis who demonstrated dramatic improvement in HPS after withdrawal from chronic methadone therapy." | 7.76 | Improvement in hepatopulmonary syndrome after methadone withdrawal: a case report with implications for disease mechanism. ( Lau, EM; McCaughan, G; Torzillo, PJ, 2010) |
| "Methadone maintenance treatment program patients were referred, evaluated by the internist and hepatologist in hepatitis clinic and provided HCV treatment with integration between both sites." | 5.38 | Integrated internist - addiction medicine - hepatology model for hepatitis C management for individuals on methadone maintenance. ( Beeder, AB; Dimova, R; Kreek, MJ; Marks, KM; Martinez, AD; Talal, AH; Zeremski, M, 2012) |
| " Methadone maintenance therapy is an accepted form of treatment for chronic opiate (eg, heroin) addiction and, not surprisingly, a significant proportion of methadone-treated patients have chronic hepatitis C." | 4.86 | Methadone maintenance therapy in liver transplantation. ( Greanya, ED; Haque, M; Jiao, M; Soos, JG; Yoshida, EM, 2010) |
| " Follow-up images showed resolution of hepatopulmonary syndrome following methadone withdrawal although there had been no improvement in his liver disease." | 3.77 | Resolution of hepatopulmonary syndrome after methadone withdrawal as demonstrated by right to left shunt study. ( Allman, KC; Kitzing, B; Torzillo, PJ, 2011) |
| " We report the case of a 50-year-old man with hepatitis C cirrhosis who demonstrated dramatic improvement in HPS after withdrawal from chronic methadone therapy." | 3.76 | Improvement in hepatopulmonary syndrome after methadone withdrawal: a case report with implications for disease mechanism. ( Lau, EM; McCaughan, G; Torzillo, PJ, 2010) |
| "Approximately 85% of patients receiving methadone maintenance therapy (MMT) for opiate dependence in the United States are infected with hepatitis C virus (HCV)." | 3.72 | A matched comparison study of medical and psychiatric complications and anesthesia and analgesia requirements in methadone-maintained liver transplant recipients. ( Atanda, A; Barnett, R; DePiano, M; Lynch, KG; Olthoff, KM; Weinrieb, RM, 2004) |
| " Among 42 active heroin users or former heroin addicts maintained on methadone, 79% were heavy alcohol abusers." | 3.65 | The spectrum and causes of liver diseases in narcotic addicts. ( Gelb, AM; Mildvan, D; Stenger, RJ, 1977) |
| "Although opioid use disorder (OUD) is common in patients with cirrhosis, it is unclear how medication treatment for OUD (MOUD) is used in this population." | 1.62 | Medication Treatment of Active Opioid Use Disorder in Veterans With Cirrhosis. ( Agbalajobi, O; Belperio, P; Fine, MJ; Gellad, W; Good, CB; Kraemer, K; Morgan, T; Rogal, S; Youk, A; Zhang, H, 2021) |
| "Methadone maintenance treatment program patients were referred, evaluated by the internist and hepatologist in hepatitis clinic and provided HCV treatment with integration between both sites." | 1.38 | Integrated internist - addiction medicine - hepatology model for hepatitis C management for individuals on methadone maintenance. ( Beeder, AB; Dimova, R; Kreek, MJ; Marks, KM; Martinez, AD; Talal, AH; Zeremski, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (26.32) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
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| Kotsis, F | 1 |
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| Eckardt, KU | 1 |
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| Li, H | 4 |
| Yao, L | 2 |
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| Zhu, Z | 1 |
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| Gentile, GL | 1 |
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| Lee, JH | 2 |
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| Lee, EJ | 1 |
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| Delorme, M | 1 |
| Bouchard, PA | 1 |
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| D'Urzo, KA | 1 |
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| Koneru, B | 1 |
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| Macha, SJ | 1 |
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| Rokita, JL | 1 |
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| Wheeler, DA | 1 |
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| Hartley, AM | 2 |
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| Gilson, E | 1 |
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| Zhang, Y | 6 |
| Hu, Z | 1 |
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| Starenki, D | 1 |
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| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 7 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
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| de Jong, M | 1 |
| Gijsen, FJH | 1 |
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| Pérez-Camargo, D | 1 |
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| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
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| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
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| van Haard, PMM | 1 |
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| Zhu, X | 1 |
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| Xu, H | 2 |
| Yang, G | 2 |
| Lin, Z | 1 |
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| Abd El-Ghafar, OA | 1 |
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| Li, J | 7 |
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| Yu, X | 2 |
| Wu, Y | 2 |
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| Hayton, TW | 1 |
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| Zhao, W | 2 |
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4 reviews available for methadone and Liver Cirrhosis
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Methadone maintenance therapy in liver transplantation.
Topics: Analgesia; Contraindications; Drug Monitoring; Evidence-Based Practice; Feasibility Studies; Graft S | 2010 |
Critical issues in the treatment of hepatitis C virus infection in methadone maintenance patients.
Topics: Analgesics, Opioid; Antiviral Agents; Delivery of Health Care, Integrated; Hepatitis C, Chronic; HIV | 2008 |
Effect of disease states on plasma protein binding of drugs.
Topics: Blood Proteins; Blood Urea Nitrogen; Creatinine; Dapsone; Digitoxin; Drug Interactions; Humans; Hypo | 1974 |
2 trials available for methadone and Liver Cirrhosis
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Postoperative pain relief after hepatic resection in cirrhotic patients: the efficacy of a single small dose of ketamine plus morphine epidurally.
Topics: Acetaminophen; Adult; Aged; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Anesthetics, Dissoc | 2003 |
14 other studies available for methadone and Liver Cirrhosis
| Article | Year |
|---|---|
Medication Treatment of Active Opioid Use Disorder in Veterans With Cirrhosis.
Topics: Age Factors; Alcoholism; Analgesics, Opioid; Buprenorphine; Cohort Studies; Female; Hepatitis C, Chr | 2021 |
Liver damage indices as a tool for modifying methadone maintenance treatment: a cross-sectional study.
Topics: Adult; Analgesics, Opioid; Aspartate Aminotransferases; Cross-Sectional Studies; Hepatitis C, Chroni | 2018 |
Improvement in hepatopulmonary syndrome after methadone withdrawal: a case report with implications for disease mechanism.
Topics: Hepatitis C; Hepatopulmonary Syndrome; Humans; Liver Cirrhosis; Male; Methadone; Middle Aged; Narcot | 2010 |
Integrated internist - addiction medicine - hepatology model for hepatitis C management for individuals on methadone maintenance.
Topics: Adult; Antiviral Agents; Behavior, Addictive; Disease Management; Female; Genotype; Hepacivirus; Hep | 2012 |
Resolution of hepatopulmonary syndrome after methadone withdrawal as demonstrated by right to left shunt study.
Topics: Anastomosis, Surgical; Hepatopulmonary Syndrome; Humans; Liver Cirrhosis; Male; Methadone; Middle Ag | 2011 |
Methadone, codeine and acute haemorrhagic necrotising pancreatitis: which came first?
Topics: Abdominal Pain; Adult; Analgesics, Opioid; Codeine; Fatty Liver; Female; Hemorrhage; Humans; Liver C | 2013 |
Preliminary clinical study of dipipanone hydrochloride (pipadone) in anaesthesia.
Topics: Anesthesia; Anesthesiology; Humans; Liver Cirrhosis; Methadone | 1959 |
Survival and risk of recidivism in methadone-dependent patients undergoing liver transplantation.
Topics: Female; Graft Survival; Heroin Dependence; Humans; Immunosuppressive Agents; Liver Cirrhosis; Liver | 2003 |
A matched comparison study of medical and psychiatric complications and anesthesia and analgesia requirements in methadone-maintained liver transplant recipients.
Topics: Adult; Analgesics, Opioid; Comorbidity; Female; Hepatitis C; Humans; Liver Cirrhosis; Liver Transpla | 2004 |
[Chronic fatigue. IV--Assessment of a 40-year-old patient].
Topics: Adult; Anemia, Iron-Deficiency; Antiviral Agents; Diagnosis, Differential; Drug Therapy, Combination | 2007 |
Hepatitis C, B, D, and A: contrasting features and liver function abnormalities in heroin addicts.
Topics: Carrier State; Hepatitis A; Hepatitis B; Hepatitis C; Hepatitis D; Heroin Dependence; Humans; Liver | 2001 |
The spectrum and causes of liver diseases in narcotic addicts.
Topics: Acute Disease; Alcoholism; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Chronic Disease; | 1977 |
Influence of disease on binding of drugs to plasma proteins.
Topics: Arrhythmias, Cardiac; Arteriosclerosis; Blood Proteins; Blood Urea Nitrogen; Carbon Radioisotopes; C | 1973 |
Hyperimmunoglobulinemia associated with narcotic addiction. Effects of methadone maintenance treatment.
Topics: Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blood Protein Disorders; Female | 1973 |