methadone has been researched along with Hypotension in 7 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In healthy dogs premedicated with dexmedetomidine and methadone and maintained under GA with isoflurane and a femoral and sciatic nerve block, there was no relationship between the specific gravity of urine collected after premedication and intraoperative arterial hypotension." | 8.31 | Evaluation of urine specific gravity as a predictor of hypotension during anaesthesia in healthy dogs premedicated with dexmedetomidine. ( Le Chevallier, D; MacFarlane, PD; van Oostrom, H, 2023) |
| "A patient with methadone-induced pulmonary edema had increased extravascular water in the lungs and a reduced total vascular albumin space." | 7.65 | Methadone-induced pulmonary edema. ( Klassen, G; Knight, L; Presant, S, 1975) |
| "In healthy dogs premedicated with dexmedetomidine and methadone and maintained under GA with isoflurane and a femoral and sciatic nerve block, there was no relationship between the specific gravity of urine collected after premedication and intraoperative arterial hypotension." | 4.31 | Evaluation of urine specific gravity as a predictor of hypotension during anaesthesia in healthy dogs premedicated with dexmedetomidine. ( Le Chevallier, D; MacFarlane, PD; van Oostrom, H, 2023) |
| "A patient with methadone-induced pulmonary edema had increased extravascular water in the lungs and a reduced total vascular albumin space." | 3.65 | Methadone-induced pulmonary edema. ( Klassen, G; Knight, L; Presant, S, 1975) |
| " We systematically searched for studies of acute toxicity of quetiapine or other antipsychotics combined with morphine or methadone." | 2.72 | Quetiapine and other antipsychotics combined with opioids in legal autopsy cases: A random finding or cause of fatal outcome? ( Andersen, CU; Andersen, FD; Simonsen, U, 2021) |
| "As clonidine was the most effective drug in terms of preservation of pre-operative lung function, it may be clinically advantageous in post-thoracotomy patients." | 2.71 | Epidural clonidine, bupivacaine and methadone as the sole analgesic agent after thoracotomy for lung resection. ( Drenger, B; Gozal, Y; Matot, I; Shauli, A; Weissman, C, 2004) |
| "Significant differences in levels of withdrawal symptoms were found on days 11, 13-15 and 17-20, symptoms resolving most rapidly in the 5-day lofexidine treatment group, whilst withdrawal responses in the 10-day lofexidine treatment group were intermediate between the 5-day lofexidine and standard methadone treatment conditions." | 2.69 | Accelerated lofexidine treatment regimen compared with conventional lofexidine and methadone treatment for in-patient opiate detoxification. ( Bearn, J; Gossop, M; Strang, J, 1998) |
| "Clonidine is a central alpha adrenergic agonist which can be used to treat the opiate withdrawal syndrome." | 2.37 | Clonidine and the treatment of the opiate withdrawal syndrome. ( Gossop, M, 1988) |
| "Where hypotension was present, the method of and response to treatment was recorded." | 1.36 | A comparison of anesthetic complications between diabetic and nondiabetic dogs undergoing phacoemulsification cataract surgery: a retrospective study. ( Clark, L; Corletto, F; Gould, DJ; Oliver, JA, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Le Chevallier, D | 1 |
| van Oostrom, H | 1 |
| MacFarlane, PD | 1 |
| Andersen, FD | 1 |
| Simonsen, U | 1 |
| Andersen, CU | 1 |
| Oliver, JA | 1 |
| Clark, L | 1 |
| Corletto, F | 1 |
| Gould, DJ | 1 |
| Matot, I | 1 |
| Drenger, B | 1 |
| Weissman, C | 1 |
| Shauli, A | 1 |
| Gozal, Y | 1 |
| Bearn, J | 1 |
| Gossop, M | 2 |
| Strang, J | 1 |
| Presant, S | 1 |
| Knight, L | 1 |
| Klassen, G | 1 |
2 reviews available for methadone and Hypotension
| Article | Year |
|---|---|
Quetiapine and other antipsychotics combined with opioids in legal autopsy cases: A random finding or cause of fatal outcome?
Topics: Adolescent; Adult; Analgesics, Opioid; Animals; Antipsychotic Agents; Arrhythmias, Cardiac; Autopsy; | 2021 |
Clonidine and the treatment of the opiate withdrawal syndrome.
Topics: Clonidine; Humans; Hypotension; Methadone; Naltrexone; Narcotics; Substance Withdrawal Syndrome | 1988 |
2 trials available for methadone and Hypotension
| Article | Year |
|---|---|
Epidural clonidine, bupivacaine and methadone as the sole analgesic agent after thoracotomy for lung resection.
Topics: Adult; Aged; Analgesia, Epidural; Analgesics; Bupivacaine; Clonidine; Double-Blind Method; Female; H | 2004 |
Accelerated lofexidine treatment regimen compared with conventional lofexidine and methadone treatment for in-patient opiate detoxification.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Clonidine; Dose-Response Relationship, Drug; D | 1998 |
3 other studies available for methadone and Hypotension
| Article | Year |
|---|---|
Evaluation of urine specific gravity as a predictor of hypotension during anaesthesia in healthy dogs premedicated with dexmedetomidine.
Topics: Anesthesia, General; Animals; Cohort Studies; Dexmedetomidine; Dog Diseases; Dogs; Hypotension; Isof | 2023 |
A comparison of anesthetic complications between diabetic and nondiabetic dogs undergoing phacoemulsification cataract surgery: a retrospective study.
Topics: Acepromazine; Anesthesia, Intravenous; Animals; Bradycardia; Cataract; Diabetes Mellitus; Dog Diseas | 2010 |
Methadone-induced pulmonary edema.
Topics: Adult; Body Water; Capillary Permeability; Diuretics; Humans; Hypotension; Male; Methadone; Pulmonar | 1975 |