methadone has been researched along with Hypercapnia in 8 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methadone is a long-acting mu-opioid and is an effective treatment for heroin addiction." | 5.33 | Ventilatory responses to hypoxia and hypercapnia in stable methadone maintenance treatment patients. ( Cunnington, D; Drummer, OH; Kronborg, I; Quinnell, T; Teichtahl, H; Tran, H; Wang, D, 2005) |
| "Respiratory responses to hypercapnia and added airway resistance were studied before and after methadone intake in 7 normal subjects (Group I) and 7 subjects receiving chronic methadone maintenance therapy (Group II)." | 3.66 | Respiratory consequences of methadone: the response to added resistance to breathing. ( Edelman, NH; Goldblatt, K; Pugliese, AC; Santiago, TV; Winters, K, 1980) |
| "Methadone is a long-acting mu-opioid and is an effective treatment for heroin addiction." | 1.33 | Ventilatory responses to hypoxia and hypercapnia in stable methadone maintenance treatment patients. ( Cunnington, D; Drummer, OH; Kronborg, I; Quinnell, T; Teichtahl, H; Tran, H; Wang, D, 2005) |
| "Thirty percent of MMT patients had a central apnea index (CAI) > 5, and 20% had a CAI > 10." | 1.33 | Central sleep apnea in stable methadone maintenance treatment patients. ( Cherry, G; Cunnington, D; Drummer, O; Goodman, C; Kronborg, I; Teichtahl, H; Wang, D, 2005) |
| "Methadone was decreased to 50 mg daily and diazepam was tapered to zero." | 1.30 | Fluvoxamine-methadone interaction. ( Alderman, CP; Frith, PA, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Teichtahl, H | 2 |
| Wang, D | 2 |
| Cunnington, D | 2 |
| Quinnell, T | 1 |
| Tran, H | 1 |
| Kronborg, I | 2 |
| Drummer, OH | 1 |
| Drummer, O | 1 |
| Goodman, C | 1 |
| Cherry, G | 1 |
| Santiago, TV | 2 |
| Goldblatt, K | 1 |
| Winters, K | 1 |
| Pugliese, AC | 2 |
| Edelman, NH | 2 |
| Alderman, CP | 1 |
| Frith, PA | 1 |
| Hargrave, SA | 1 |
| Legge, JS | 1 |
| Palmer, KN | 1 |
| Marks, CE | 2 |
| Goldring, RM | 2 |
| Sapira, JD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Acute Intravenous Morphine Administration on Sleep Disordered Breathing (SDB) in Patients With Moderate Obstructive Sleep Apnoea (OSA): A Paired Design Trial[NCT03127800] | Phase 3 | 6 participants (Actual) | Interventional | 2016-05-20 | Terminated (stopped due to Difficulties with recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for methadone and Hypercapnia
| Article | Year |
|---|---|
Ventilatory responses to hypoxia and hypercapnia in stable methadone maintenance treatment patients.
Topics: Adult; Female; Heroin Dependence; Humans; Hypercapnia; Hypoxia; Male; Methadone; Narcotics; Pulmonar | 2005 |
Central sleep apnea in stable methadone maintenance treatment patients.
Topics: Adult; Female; Heroin Dependence; Humans; Hypercapnia; Hypoxia; Male; Methadone; Narcotics; Polysomn | 2005 |
Respiratory consequences of methadone: the response to added resistance to breathing.
Topics: Adult; Airway Resistance; Carbon Dioxide; Female; Heroin Dependence; Humans; Hypercapnia; Male; Meth | 1980 |
Fluvoxamine-methadone interaction.
Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Drug Interactions; Female; Flu | 1999 |
Control of breathing during methadone addiction.
Topics: Adult; Blood Gas Analysis; Humans; Hypercapnia; Hypoxia; Lung; Methadone; Respiration; Respiratory F | 1977 |
Postoperative ventilatory failure in a patient with primary alveolar hypoventilation. A case report.
Topics: Appendectomy; Carbon Dioxide; Cheyne-Stokes Respiration; Female; Humans; Hydrogen-Ion Concentration; | 1973 |
Chronic hypercapnia during methadone maintenance.
Topics: Adult; Chronic Disease; Female; Heroin Dependence; Humans; Hypercapnia; Hypoventilation; Male; Metha | 1973 |
Correspondence: Chronic hypercapnia during methadone maintenance.
Topics: Humans; Hypercapnia; Methadone; Substance-Related Disorders | 1974 |