methadone has been researched along with Hospital-Acquired Condition in 9 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Takotsubo cardiomyopathy is a syndrome characterized by transient apical ballooning or reversible midventricular systolic dysfunction." | 5.37 | Takotsubo cardiomyopathy due to iatrogenic methadone withdrawal. ( Bhat, T; Duvvuri, S; Jun, CH; Khattri, S; Lafferty, J; Saiful, FB; Teli, S, 2011) |
| " Different approaches, such as weight-based and formula-based methods, have been used to determine the initial methadone dosing regimen." | 2.48 | Selection of the initial methadone regimen for the management of iatrogenic opioid abstinence syndrome in critically ill children. ( Boyles, KA; Johnson, PN; Miller, JL, 2012) |
| "Methadone is frequently used to prevent withdrawal symptoms secondary to intended therapeutic opiate exposure." | 1.62 | Iatrogenic Opiate Withdrawal in Pediatric Patients: Implementation of a Standardized Methadone Weaning Protocol and Withdrawal Assessment Tool. ( Izquierdo, M; Lavandosky, G; Rodriguez, JC; Stevens, JS; Walters, RA, 2021) |
| "Takotsubo cardiomyopathy is a syndrome characterized by transient apical ballooning or reversible midventricular systolic dysfunction." | 1.37 | Takotsubo cardiomyopathy due to iatrogenic methadone withdrawal. ( Bhat, T; Duvvuri, S; Jun, CH; Khattri, S; Lafferty, J; Saiful, FB; Teli, S, 2011) |
| " The switch to oral agents must take into consideration the differences in potency, half-life, and oral bioavailability between the agents." | 1.29 | Outpatient therapy of iatrogenic drug dependency following prolonged sedation in the pediatric intensive care unit. ( Deshpande, JK; Gregory, DF; Tobias, JD, 1994) |
| " To prevent such mistakes in the future a change in labelling of the bottle giving directions for correct dosing is suggested." | 1.29 | [Iatrogenic methadone poisoning]. ( Rabl, W; Sigrist, T; Sutter, K, 1993) |
| "Iatrogenic, or medically induced, drug addiction is a problem affecting both patients and physicians." | 1.27 | Medically induced drug addiction. ( Portnow, JM; Strassman, HD, 1985) |
| "Despite the vast literature on drug dependence, little has been written about patients who become addicted while taking medically prescribed drugs for organic pathology." | 1.26 | Treatment of iatrogenic drug dependence in the general hospital. ( Streltzer, J, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Walters, RA | 1 |
| Izquierdo, M | 1 |
| Rodriguez, JC | 1 |
| Stevens, JS | 1 |
| Lavandosky, G | 1 |
| Saiful, FB | 1 |
| Lafferty, J | 1 |
| Jun, CH | 1 |
| Teli, S | 1 |
| Duvvuri, S | 1 |
| Khattri, S | 1 |
| Bhat, T | 1 |
| Johnson, PN | 1 |
| Boyles, KA | 1 |
| Miller, JL | 1 |
| Streltzer, J | 1 |
| Tobias, JD | 1 |
| Deshpande, JK | 1 |
| Gregory, DF | 1 |
| Rabl, W | 1 |
| Sigrist, T | 1 |
| Sutter, K | 1 |
| Walker, L | 1 |
| Jiang, Z | 1 |
| Portnow, JM | 1 |
| Strassman, HD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Adjunct Methadone to Decrease the Duration of Mechanical Ventilation in the Medical Intensive Care Unit[NCT02025855] | Phase 4 | 46 participants (Anticipated) | Interventional | 2014-01-31 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for methadone and Hospital-Acquired Condition
| Article | Year |
|---|---|
Selection of the initial methadone regimen for the management of iatrogenic opioid abstinence syndrome in critically ill children.
Topics: Analgesics, Opioid; Child; Clinical Trials as Topic; Critical Illness; Disease Management; Dose-Resp | 2012 |
8 other studies available for methadone and Hospital-Acquired Condition
| Article | Year |
|---|---|
Iatrogenic Opiate Withdrawal in Pediatric Patients: Implementation of a Standardized Methadone Weaning Protocol and Withdrawal Assessment Tool.
Topics: Analgesics, Opioid; Child; Humans; Iatrogenic Disease; Methadone; Opiate Alkaloids; Substance Withdr | 2021 |
Takotsubo cardiomyopathy due to iatrogenic methadone withdrawal.
Topics: Analgesics, Opioid; Coronary Angiography; Drug Overdose; Echocardiography; Electrocardiography; Huma | 2011 |
Treatment of iatrogenic drug dependence in the general hospital.
Topics: Aged; Female; Humans; Iatrogenic Disease; Inactivation, Metabolic; Male; Methadone; Middle Aged; Opi | 1980 |
Outpatient therapy of iatrogenic drug dependency following prolonged sedation in the pediatric intensive care unit.
Topics: Child; Female; Fentanyl; Humans; Iatrogenic Disease; Infant; Lorazepam; Male; Methadone; Midazolam; | 1994 |
[Iatrogenic methadone poisoning].
Topics: Adult; Female; Heroin Dependence; Humans; Iatrogenic Disease; Male; Medication Errors; Methadone | 1993 |
Iatrogenic addiction and its treatment.
Topics: Adult; Aged; Behavior Therapy; Denial, Psychological; Female; Humans; Iatrogenic Disease; Life Style | 1978 |
[Iatrogenic addiction of pethidine: clinical feature and experience of detoxification].
Topics: Adult; Clonidine; Female; Humans; Iatrogenic Disease; Male; Meperidine; Methadone; Substance-Related | 1992 |
Medically induced drug addiction.
Topics: Adult; Aged; Analgesics, Opioid; Combined Modality Therapy; Counseling; Female; Humans; Iatrogenic D | 1985 |