methadone has been researched along with Emesis, Postoperative in 7 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adolescents undergoing posterior spinal fusion (PSF) for idiopathic scoliosis or pectus excavatum (PE) repair received methadone intraoperatively (0." | 5.41 | A Novel Perioperative Multidose Methadone-Based Multimodal Analgesic Strategy in Children Achieved Safe and Low Analgesic Blood Methadone Levels Enabling Opioid-Sparing Sustained Analgesia With Minimal Adverse Effects. ( Aruldhas, BW; Fitzgerald, RE; Overholser, BR; Packiasabapathy, S; Quinney, SK; Renschler, JS; Sadhasivam, S; Zang, Y; Zhang, P, 2021) |
| "Methadone has several desirable pharmacological features, including a long elimination half-life." | 2.90 | Intraoperative methadone for postoperative pain after laparoscopic hysterectomy: Protocol for a randomised, double-blind trial. ( Brix, LD; Friesgaard, KD; Kristensen, CB; Nikolajsen, L; Rian, O, 2019) |
| "Postoperative pain is not adequately managed in greater than 40% of surgical patients and is a high priority for perioperative research." | 2.66 | Intraoperative methadone administration and postoperative pain control: a systematic review and meta-analysis. ( D'Souza, RS; Gurrieri, C; Johnson, RL; Warner, N; Wittwer, E, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 5 (71.43) | 2.80 |
| Authors | Studies |
|---|---|
| Ryan, AC | 1 |
| Murrell, JC | 1 |
| Gurney, MA | 1 |
| Eisenbraun, A | 1 |
| Schroeder, D | 1 |
| Schaff, HV | 1 |
| Martin, E | 1 |
| Wittwer, ED | 1 |
| D'Souza, RS | 1 |
| Gurrieri, C | 1 |
| Johnson, RL | 1 |
| Warner, N | 1 |
| Wittwer, E | 1 |
| Pontes, JPJ | 1 |
| Braz, FR | 1 |
| Módolo, NSP | 1 |
| Mattar, LA | 1 |
| Sousa, JAG | 1 |
| Navarro E Lima, LH | 1 |
| Sadhasivam, S | 1 |
| Aruldhas, BW | 1 |
| Packiasabapathy, S | 1 |
| Overholser, BR | 1 |
| Zhang, P | 1 |
| Zang, Y | 1 |
| Renschler, JS | 1 |
| Fitzgerald, RE | 1 |
| Quinney, SK | 1 |
| Friesgaard, KD | 1 |
| Brix, LD | 1 |
| Kristensen, CB | 1 |
| Rian, O | 1 |
| Nikolajsen, L | 1 |
| Higa, KD | 1 |
| Ho, T | 1 |
| Boone, KB | 1 |
| Roubicek, MC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacogenetics and Pharmacokinetics of Oxycodone to Personalize Postoperative Pain Management Following Major Inpatient Surgery in Children[NCT03495388] | 500 participants (Anticipated) | Observational | 2018-04-01 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for methadone and Emesis, Postoperative
| Article | Year |
|---|---|
Intraoperative methadone administration and postoperative pain control: a systematic review and meta-analysis.
Topics: Airway Extubation; Analgesics, Opioid; Humans; Hypoxia; Intraoperative Care; Length of Stay; Methado | 2020 |
3 trials available for methadone and Emesis, Postoperative
| Article | Year |
|---|---|
Intra-operative methadone effect on quality of recovery compared with morphine following laparoscopic gastroplasty: a randomised controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia Recovery Period; Double-Blind M | 2021 |
A Novel Perioperative Multidose Methadone-Based Multimodal Analgesic Strategy in Children Achieved Safe and Low Analgesic Blood Methadone Levels Enabling Opioid-Sparing Sustained Analgesia With Minimal Adverse Effects.
Topics: Adolescent; Age Factors; Analgesics, Opioid; Child; Drug Administration Schedule; Drug Monitoring; F | 2021 |
Intraoperative methadone for postoperative pain after laparoscopic hysterectomy: Protocol for a randomised, double-blind trial.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Cough; Critical Care; Double-Blind Method; Female; Huma | 2019 |
3 other studies available for methadone and Emesis, Postoperative
| Article | Year |
|---|---|
Post-operative nausea and vomiting (PONV) observed in a clinical study designed to assess the analgesic effects of intravenous and subcutaneous methadone in dogs.
Topics: Analgesia; Analgesics, Opioid; Animals; Bupivacaine; Dog Diseases; Dogs; Methadone; Pain, Postoperat | 2022 |
Single-Center Retrospective Comparison of Opioid-Based and Multimodal Analgesic Regimens in Adult Cardiac Surgery.
Topics: Adult; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Dexmedetomidine; Humans; Methado | 2023 |
Narcotic withdrawal syndrome following gastric bypass--a difficult diagnosis.
Topics: Adult; Behavior, Addictive; Diagnosis, Differential; Female; Gastric Bypass; Humans; Methadone; Opio | 2001 |