methadone has been researched along with Embryopathies in 10 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, concerns about neonatal abstinence syndrome (NAS) in methadone-exposed neonates have resulted in efforts to withdraw women from methadone during pregnancy or to use buprenorphine, a mixed agonist/antagonist opiate in place of methadone." | 4.88 | Intrauterine abstinence syndrome (IAS) during buprenorphine inductions and methadone tapers: can we assure the safety of the fetus? ( McCarthy, JJ, 2012) |
| "This paper describes patterns of drug use such as choice of drug, other substances abused, and route of administration in 174 women who reported methamphetamine, cocaine, heroin, or "Ts and blues" abuse during pregnancy." | 3.68 | Patterns of multiple substance abuse during pregnancy: implications for mother and fetus. ( Gilstrap, LD; Johnston, WL; Little, BB; Snell, LM, 1990) |
| "Women with opioid use disorder who become pregnant are a particularly vulnerable population and require a comprehensive treatment approach for mother and fetus." | 2.61 | Opioid use disorder during pregnancy: An overview. ( Carter, LC; Nicholas, JS; Read, L; Read, MA; Schmidt, E, 2019) |
| " Recommendations are made for further research into physician/patient interactions and into optimal dosing of methadone and buprenorphine to minimize maternal/fetal withdrawal." | 2.55 | Opioid dependence and pregnancy: minimizing stress on the fetal brain. ( Fassbender, C; Finnegan, LP; Leamon, MH; McCarthy, JJ, 2017) |
| "There are multiple causes for intrauterine growth retardation but one etiology proposed is maternal drugs." | 1.27 | Maternal drug therapy: effect on fetal and neonatal growth and neurobehavior. ( Hill, RM; Tennyson, LM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carter, LC | 1 |
| Read, MA | 1 |
| Read, L | 1 |
| Nicholas, JS | 1 |
| Schmidt, E | 1 |
| McCarthy, JJ | 2 |
| Leamon, MH | 1 |
| Finnegan, LP | 1 |
| Fassbender, C | 1 |
| Lemons, PK | 1 |
| Bashore, RA | 1 |
| Ketchum, JS | 1 |
| Staisch, KJ | 1 |
| Barrett, CT | 1 |
| Zimmermann, EG | 1 |
| Daly, CA | 1 |
| Freeman, J | 1 |
| Weston, W | 1 |
| Kovar, I | 1 |
| Phelan, M | 1 |
| Guerra-Romero, L | 1 |
| Noguer, I | 1 |
| Bolea, A | 1 |
| Suárez, M | 1 |
| Parras, F | 1 |
| Little, BB | 1 |
| Snell, LM | 1 |
| Gilstrap, LD | 1 |
| Johnston, WL | 1 |
| Hill, RM | 1 |
| Tennyson, LM | 1 |
| Sparber, SB | 1 |
6 reviews available for methadone and Embryopathies
| Article | Year |
|---|---|
Opioid use disorder during pregnancy: An overview.
Topics: Adolescent; Adult; Analgesics, Opioid; Buprenorphine; Cognitive Behavioral Therapy; Female; Fetal Di | 2019 |
Opioid dependence and pregnancy: minimizing stress on the fetal brain.
Topics: Brain Diseases; Buprenorphine; Female; Fetal Diseases; Humans; Methadone; Opioid-Related Disorders; | 2017 |
Intrauterine abstinence syndrome (IAS) during buprenorphine inductions and methadone tapers: can we assure the safety of the fetus?
Topics: Buprenorphine; Epigenesis, Genetic; Female; Fetal Diseases; Humans; Methadone; Narcotics; Pregnancy; | 2012 |
Prenatal diagnosis of amniotic band syndrome in a methadone user: review of the literature and a case report.
Topics: Adult; Amniotic Band Syndrome; Female; Fetal Diseases; Forearm; Gestational Age; Humans; Infant, New | 1996 |
[Preventing HIV infection: an exercise in evaluating scientific evidence in public health].
Topics: Adult; Anti-HIV Agents; Biological Products; Clinical Trials as Topic; Evidence-Based Medicine; Fema | 1999 |
Developmental effects of narcotics.
Topics: Analysis of Variance; Animals; Body Weight; Female; Fetal Diseases; Growth; Humans; Methadone; Nalox | 1986 |
4 other studies available for methadone and Embryopathies
| Article | Year |
|---|---|
The sequelea to addiction.
Topics: Female; Fetal Alcohol Spectrum Disorders; Fetal Diseases; Heroin; Humans; Methadone; Opioid-Related | 1983 |
Heroin addiction and pregnancy.
Topics: Animals; Female; Fetal Diseases; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseas | 1981 |
Patterns of multiple substance abuse during pregnancy: implications for mother and fetus.
Topics: Adolescent; Adult; Age Factors; Alcoholism; Cocaine; Female; Fetal Diseases; Heroin; Humans; Marijua | 1990 |
Maternal drug therapy: effect on fetal and neonatal growth and neurobehavior.
Topics: Aminopterin; Amphetamines; Animals; Anticoagulants; Anticonvulsants; Antihypertensive Agents; Birth | 1986 |