methadone has been researched along with Depression, Endogenous in 84 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients receiving methadone hydrochloride maintenance treatment were selected if they met the criteria for a DSM-III-R depressive disorder that was chronologically primary, had persisted during a past abstinent period or was long-standing, and persisted during at least 1 month of stable methadone treatment." | 9.08 | Imipramine treatment of opiate-dependent patients with depressive disorders. A placebo-controlled trial. ( Brady, R; Deliyannides, D; Donovan, SJ; Koenig, T; McGrath, PJ; Nunes, EV; Ocepek-Welikson, K; Quitkin, FM; Woody, G, 1998) |
| "This study tested the effectiveness of fluoxetine as a treatment for depression in a population of methadone-maintained opioid addicts." | 9.08 | Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts. ( Carroll, KM; Gordon, L; Kosten, T; Nich, C; Petrakis, I; Rounsaville, B, 1998) |
| "The success of rehabilitation is not influenced solely by drug abstinence, but also by the state of general health and well-being, which for patients in methadone maintenance treatment (MMT) frequently is compromised by experiencing pain, depression and sleep disorders." | 7.78 | Pain depression and sleep disorders among methadone maintenance treatment patients. ( Lawental, E; Pud, D; Zlotnick, C, 2012) |
| "Evaluation of delirium should include close investigation of the patient's medications for potential interactions with dextromethorphan." | 7.73 | Dextromethorphan-induced delirium and possible methadone interaction. ( Lotrich, FE; Pollock, BG; Rosen, J, 2005) |
| "Patients receiving methadone hydrochloride maintenance treatment were selected if they met the criteria for a DSM-III-R depressive disorder that was chronologically primary, had persisted during a past abstinent period or was long-standing, and persisted during at least 1 month of stable methadone treatment." | 5.08 | Imipramine treatment of opiate-dependent patients with depressive disorders. A placebo-controlled trial. ( Brady, R; Deliyannides, D; Donovan, SJ; Koenig, T; McGrath, PJ; Nunes, EV; Ocepek-Welikson, K; Quitkin, FM; Woody, G, 1998) |
| "This study tested the effectiveness of fluoxetine as a treatment for depression in a population of methadone-maintained opioid addicts." | 5.08 | Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts. ( Carroll, KM; Gordon, L; Kosten, T; Nich, C; Petrakis, I; Rounsaville, B, 1998) |
| "The success of rehabilitation is not influenced solely by drug abstinence, but also by the state of general health and well-being, which for patients in methadone maintenance treatment (MMT) frequently is compromised by experiencing pain, depression and sleep disorders." | 3.78 | Pain depression and sleep disorders among methadone maintenance treatment patients. ( Lawental, E; Pud, D; Zlotnick, C, 2012) |
| "Evaluation of delirium should include close investigation of the patient's medications for potential interactions with dextromethorphan." | 3.73 | Dextromethorphan-induced delirium and possible methadone interaction. ( Lotrich, FE; Pollock, BG; Rosen, J, 2005) |
| " BTDD may be a useful adjunct to methadone maintenance for treating comorbid depressive disorders." | 3.73 | Behavior therapy for depression in drug dependence (BTDD): results of a stage Ia therapy development pilot. ( Aharonovich, E; Carpenter, KM; Iguchi, MY; Nunes, EV; Smith, JL, 2006) |
| "Self-reported depressive symptoms of opiate addicts were assessed at admission to a methadone treatment program and weekly during the first 4 treatment weeks using the Beck Depression Inventory." | 3.68 | Early treatment time course of depressive symptoms in opiate addicts. ( Bigelow, GE; Stitzer, ML; Strain, EC, 1991) |
| "Psychiatric disorders have become an increasing concern in the treatment of substance abusers." | 2.67 | Psychiatric disorders of opioid addicts entering treatment: preliminary data. ( Abbott, PJ; Walker, SR; Weller, SB, 1994) |
| "Thus, antisocial personality disorder was a poor prognostic factor for treatment retention and continued cocaine abuse, and medication did not improve treatment outcome for the ASP patients, but did for the non-ASP patients." | 2.67 | Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence. ( Kosten, T; Leal, J; Ziedonis, D, 1994) |
| "Four groups were compared: those with opiate dependence alone (N = 16); opiate dependence plus depression (N = 16); opiate dependence plus depression plus antisocial personality disorder (N = 17); and opiate dependence plus antisocial personality disorder (N = 13)." | 2.66 | Sociopathy and psychotherapy outcome. ( Luborsky, L; McLellan, AT; O'Brien, CP; Woody, GE, 1985) |
| "Doxepin was superior to placebo on Clinical Global Impressions and several factors of the Hamilton Rating Scale for Depression and the Profile of Mood States." | 2.65 | Doxepin as adjunctive therapy for depressed methadone maintenance patients: a double-blind study. ( Barranco, M; Kyle, EM; Seco, G; Titievsky, J, 1982) |
| " Antiviral treatment with pegylated interferon-alfa (IFN-alpha) plus ribavirin is often complicated by psychiatric adverse events, significantly affecting patients adherence." | 2.44 | Hepatitis C treatment in patients with drug addiction: clinical management of interferon-alpha-associated psychiatric side effects. ( Mauss, S; Schaefer, M, 2008) |
| "This article reviews the literature on treatment of depressive disorders and symptoms among patients with opiate dependence." | 2.42 | Treatment of depression in patients with opiate dependence. ( Levin, FR; Nunes, EV; Sullivan, MA, 2004) |
| "Survey concerned consumers with 862, 433 and 429 of high dosage buprenorphine and respectively methadone." | 1.43 | [Characteristics of subjects under opiate maintenance treatment in primary care using the OPEMA data 2013]. ( Amaslidou, D; Frauger, E; Gentile, G; Giocanti, A; Micallef, J; Orleans, V; Pauly, V; Thirion, X, 2016) |
| "Methadone maintenance treatment (MMT) has elevated rates of co-morbid memory deficit and depression that are associated with higher relapse rates for substance abuse." | 1.38 | White matter abnormalities correlating with memory and depression in heroin users under methadone maintenance treatment. ( Chen, CC; Chen, HL; Cheng, YF; Chou, KH; Huang, CC; Li, SH; Lin, CP; Lin, WC; Lu, CH; Wang, YL, 2012) |
| "Depressive disorders among opiate abusers have detrimental effects on their well-being and ability to refrain from illegal drugs." | 1.37 | Adapting problem-solving therapy for depressed older adults in methadone maintenance treatment. ( Morse, JQ; Reynolds, CF; Rosen, D, 2011) |
| "Amitriptyline was found in 12 (7." | 1.35 | Tricyclic antidepressants abuse, with or without benzodiazepines abuse, in former heroin addicts currently in methadone maintenance treatment (MMT). ( Adelson, M; Peles, E; Schreiber, S, 2008) |
| "Rates of specific personality disorders are reported." | 1.32 | A psychometric study of the prevalence of DSM-IV personality disorders among office-based methadone maintenance patients. ( Daiter, J; O'Connell, T; Teplin, D; Varenbut, M, 2004) |
| "Paroxetine is a strong CYP2D6 inhibitor, and these results confirm previous studies showing an involvement of CYP2D6 in methadone metabolism with a stereoselectivity toward the (R)-enantiomer." | 1.31 | Paroxetine increases steady-state concentrations of (R)-methadone in CYP2D6 extensive but not poor metabolizers. ( Baumann, P; Begré, S; Cosendai-Savary, L; Eap, CB; Golay, KP; Jaquet-Rochat, S; Kosel, M; Ladewig, D; von Bardeleben, U, 2002) |
| "Methadone was decreased to 50 mg daily and diazepam was tapered to zero." | 1.30 | Fluvoxamine-methadone interaction. ( Alderman, CP; Frith, PA, 1999) |
| "Multiple substance use disorders were found in these patients, and more substance use disorders were found in those patients with, versus without, a non-substance use psychiatric diagnosis." | 1.28 | Clustering of multiple substance use and psychiatric diagnoses in opiate addicts. ( Bigelow, GE; Brooner, RK; Strain, EC, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (23.81) | 18.7374 |
| 1990's | 35 (41.67) | 18.2507 |
| 2000's | 20 (23.81) | 29.6817 |
| 2010's | 9 (10.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pirnia, B | 1 |
| Pirnia, K | 1 |
| Mohammadpour, S | 1 |
| Malekanmehr, P | 1 |
| Soleimani, A | 1 |
| Mahmoodi, Z | 1 |
| Soleimani, AA | 1 |
| Zahiroddin, A | 1 |
| Beitel, M | 1 |
| Savant, JD | 1 |
| Cutter, CJ | 1 |
| Peters, S | 1 |
| Belisle, N | 1 |
| Barry, DT | 1 |
| Gregg, M | 1 |
| Martinez, L | 1 |
| Samaritan, G | 1 |
| Gentile, G | 1 |
| Frauger, E | 1 |
| Giocanti, A | 1 |
| Pauly, V | 1 |
| Orleans, V | 1 |
| Amaslidou, D | 1 |
| Thirion, X | 1 |
| Micallef, J | 1 |
| Brands, B | 1 |
| Blake, J | 1 |
| Marsh, DC | 1 |
| Sproule, B | 1 |
| Jeyapalan, R | 1 |
| Li, S | 1 |
| Tenore, PL | 1 |
| Maremmani, I | 1 |
| Pacini, M | 1 |
| Popovic, D | 1 |
| Romano, A | 1 |
| Maremmani, AG | 1 |
| Perugi, G | 1 |
| Deltito, J | 1 |
| Akiskal, K | 1 |
| Akiskal, H | 1 |
| Berg, KM | 1 |
| Cooperman, NA | 1 |
| Newville, H | 1 |
| Arnsten, JH | 1 |
| Schaefer, M | 1 |
| Mauss, S | 1 |
| Rosen, D | 1 |
| Morse, JQ | 1 |
| Reynolds, CF | 1 |
| Savvas, SM | 1 |
| Somogyi, AA | 1 |
| White, JM | 1 |
| Rastogi, R | 1 |
| Swarm, RA | 1 |
| Patel, TA | 1 |
| Lin, WC | 1 |
| Chou, KH | 1 |
| Chen, CC | 1 |
| Huang, CC | 1 |
| Chen, HL | 1 |
| Lu, CH | 1 |
| Li, SH | 1 |
| Wang, YL | 1 |
| Cheng, YF | 1 |
| Lin, CP | 1 |
| Pud, D | 1 |
| Zlotnick, C | 1 |
| Lawental, E | 1 |
| Eich-Höchli, D | 1 |
| Oppliger, R | 1 |
| Golay, KP | 2 |
| Baumann, P | 5 |
| Eap, CB | 4 |
| BODMAN, RI | 1 |
| SCHRAPPE, O | 1 |
| BURCHARD, JM | 1 |
| GEHLKEN, K | 1 |
| Rao, SR | 1 |
| Broome, KM | 1 |
| Simpson, DD | 2 |
| Teplin, D | 1 |
| O'Connell, T | 1 |
| Daiter, J | 1 |
| Varenbut, M | 1 |
| Nunes, EV | 7 |
| Sullivan, MA | 1 |
| Levin, FR | 1 |
| Lotrich, FE | 1 |
| Rosen, J | 1 |
| Pollock, BG | 1 |
| Raby, WN | 1 |
| Carpenter, KM | 2 |
| Aharonovich, E | 2 |
| Rubin, E | 1 |
| Bisaga, A | 1 |
| Levin, F | 1 |
| Peles, E | 3 |
| Schreiber, S | 3 |
| Naumovsky, Y | 1 |
| Adelson, M | 3 |
| Smith, JL | 1 |
| Iguchi, MY | 1 |
| Hesse, M | 1 |
| Pickar, D | 2 |
| Davis, GC | 1 |
| Schulz, SC | 1 |
| Extein, I | 2 |
| Wagner, R | 1 |
| Naber, D | 1 |
| Gold, PW | 2 |
| van Kammen, DP | 1 |
| Goodwin, FK | 2 |
| Wyatt, RJ | 1 |
| Li, CH | 1 |
| Bunney, WE | 1 |
| Rounsaville, BJ | 5 |
| Glazer, W | 1 |
| Wilber, CH | 2 |
| Weissman, MM | 4 |
| Kleber, HD | 3 |
| Prusoff, BA | 1 |
| Riordan, CE | 1 |
| Judd, LL | 2 |
| Risch, SC | 2 |
| Segal, DS | 2 |
| Janowsky, DS | 2 |
| Huey, LY | 2 |
| Ginzburg, HM | 1 |
| Allison, M | 1 |
| Hubbard, RL | 1 |
| Goldstein, JA | 1 |
| Dackis, CA | 1 |
| Pottash, AL | 2 |
| Gold, MS | 2 |
| Annitto, W | 1 |
| Woody, GE | 3 |
| O'Brien, CP | 2 |
| McLellan, AT | 3 |
| Marcovici, M | 1 |
| Evans, BD | 1 |
| Sweeney, DR | 1 |
| Ross, RJ | 1 |
| Rebard, R | 1 |
| Martin, D | 1 |
| Crits-Christoph, K | 1 |
| Wilber, C | 2 |
| Kleber, H | 2 |
| Parker, DC | 1 |
| Titievsky, J | 1 |
| Seco, G | 1 |
| Barranco, M | 1 |
| Kyle, EM | 1 |
| Treece, C | 1 |
| Nicholson, B | 1 |
| Chatham, LR | 1 |
| Knight, K | 1 |
| Joe, GW | 1 |
| Abbott, PJ | 1 |
| Weller, SB | 1 |
| Walker, SR | 1 |
| Nunes, E | 1 |
| Quitkin, F | 1 |
| Brady, R | 3 |
| Post-Koenig, T | 1 |
| Petrakis, I | 2 |
| Carroll, K | 1 |
| Gordon, L | 2 |
| Cushing, G | 1 |
| Rounsaville, B | 2 |
| Hoffmann-Richter, U | 1 |
| Streb, P | 1 |
| Drake, S | 1 |
| Swift, W | 2 |
| Hall, W | 2 |
| Ross, M | 1 |
| Milby, JB | 1 |
| Hohmann, AA | 1 |
| Gentile, M | 1 |
| Huggins, N | 1 |
| Sims, MK | 1 |
| Woody, G | 2 |
| Haas, N | 1 |
| Rousar, E | 1 |
| Brooner, RK | 2 |
| Regier, MW | 1 |
| Bigelow, GE | 3 |
| Kolar, AF | 1 |
| Brown, BS | 1 |
| Haertzen, CA | 1 |
| Michaelson, BS | 1 |
| Leal, J | 1 |
| Ziedonis, D | 1 |
| Kosten, T | 2 |
| Bertschy, G | 2 |
| Baettig, D | 1 |
| Darke, S | 1 |
| Ness, R | 1 |
| Handelsman, L | 2 |
| Aronson, MJ | 1 |
| Hershkowitz, A | 1 |
| Kanof, PD | 1 |
| Alterman, AI | 3 |
| Snider, EC | 1 |
| Cacciola, JS | 3 |
| Brown, LS | 1 |
| Zaballero, A | 1 |
| Siddiqui, N | 1 |
| Rutherford, MJ | 2 |
| McKay, JR | 2 |
| Callaway, E | 1 |
| Laqueille, X | 2 |
| Spadone, C | 1 |
| Pani, PP | 1 |
| Trogu, E | 1 |
| Contu, P | 1 |
| Agus, A | 1 |
| Gessa, GL | 1 |
| Schottenfeld, RS | 1 |
| Pakes, JR | 1 |
| Kosten, TR | 5 |
| Quitkin, FM | 2 |
| Donovan, SJ | 1 |
| Deliyannides, D | 1 |
| Ocepek-Welikson, K | 1 |
| Koenig, T | 1 |
| McGrath, PJ | 1 |
| Carroll, KM | 1 |
| Nich, C | 1 |
| Hamilton, SP | 2 |
| Klimchak, C | 1 |
| Rosenblum, A | 1 |
| Fallon, B | 1 |
| Magura, S | 1 |
| Foote, J | 1 |
| Bernstein, D | 1 |
| Alderman, CP | 1 |
| Frith, PA | 1 |
| Felder, C | 1 |
| Uehlinger, C | 1 |
| Powell, K | 1 |
| Sembach, N | 1 |
| Levy, A | 1 |
| Masmoudi, R | 1 |
| Edel, Y | 1 |
| Gratien, M | 1 |
| Davido, A | 1 |
| Janal, M | 1 |
| Weber, L | 1 |
| Turrina, C | 1 |
| Fiorazzo, A | 1 |
| Turano, A | 1 |
| Cacciani, P | 1 |
| Regini, C | 1 |
| Castelli, F | 1 |
| Sacchetti, E | 1 |
| Begré, S | 1 |
| von Bardeleben, U | 1 |
| Ladewig, D | 1 |
| Jaquet-Rochat, S | 1 |
| Cosendai-Savary, L | 1 |
| Kosel, M | 1 |
| Spring, WD | 1 |
| Willenbring, ML | 1 |
| Maddux, TL | 1 |
| Hampf, G | 1 |
| Kuoppasalmi, K | 1 |
| Henriksson, M | 1 |
| Achté, K | 1 |
| Strain, EC | 2 |
| Stitzer, ML | 1 |
| Stewart, JW | 1 |
| Hendriks, VM | 1 |
| Steer, RA | 1 |
| Platt, JJ | 1 |
| Metzger, DS | 1 |
| Gawin, FH | 1 |
| Morgan, C | 2 |
| Nelson, JC | 1 |
| Jatlow, P | 1 |
| Kosten, TA | 1 |
| Jacobsen, LK | 1 |
| Loo, H | 1 |
| Luborsky, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Randomized Comparative Effectiveness Clinical Trial of Buprenorphine vs. Methadone for the Treatment of Opioid Dependence in Pregnancy.[NCT03098407] | 55 participants (Actual) | Interventional | 2017-04-20 | Completed | |||
| Role of CYP2B6, CYP3A4, and MDR1 in the Metabolic Clearance of Methadone in Human Subjects[NCT00504413] | Phase 1 | 20 participants (Anticipated) | Interventional | 2007-07-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for methadone and Depression, Endogenous
| Article | Year |
|---|---|
Psychotherapeutic benefits of opioid agonist therapy.
Topics: Anxiety Disorders; Brain; Buprenorphine; Comorbidity; Depressive Disorder; Diagnosis, Dual (Psychiat | 2008 |
Hepatitis C treatment in patients with drug addiction: clinical management of interferon-alpha-associated psychiatric side effects.
Topics: Alcoholism; Antidepressive Agents; Antiviral Agents; Anxiety Disorders; Depressive Disorder; Drug Th | 2008 |
Case scenario: opioid association with serotonin syndrome: implications to the practitioners.
Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhi | 2011 |
Treatment of depression in patients with opiate dependence.
Topics: Affect; Antidepressive Agents; Behavior Therapy; Depressive Disorder; Humans; Methadone; Narcotics; | 2004 |
Behavioral and neuroendocrine effects of opioid receptor agonists in psychopathologic states.
Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Depressive Disorder; Endorphins; Humans; Hy | 1983 |
Antidepressant treatment in methadone maintenance patients.
Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Drug Therapy, Combinati | 1994 |
16 trials available for methadone and Depression, Endogenous
| Article | Year |
|---|---|
The effectiveness of acupuncture on HPA functional in depressed patients under methadone maintenance treatment, a randomized double-blind sham-controlled trial.
Topics: Acupuncture Therapy; Adult; Depressive Disorder; Double-Blind Method; Female; Humans; Hydrocortisone | 2018 |
Methadone maintenance treatment and St. John's Wort - a case report.
Topics: Adult; Analgesics, Opioid; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Humans | 2003 |
Temperament characteristics, as assessed by the tridimensional personality questionnaire, moderate the response to sertraline in depressed opiate-dependent methadone patients.
Topics: Adult; Cocaine-Related Disorders; Depressive Disorder; Female; Heroin Dependence; Humans; Male; Meth | 2006 |
Short-term interpersonal psychotherapy in methadone-maintained opiate addicts.
Topics: Adult; Antisocial Personality Disorder; Anxiety Disorders; Clinical Trials as Topic; Depressive Diso | 1983 |
Imipramine as treatment for depression in addicts.
Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramin | 1983 |
Methadone and morphine in depression [proceedings].
Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Met | 1981 |
Doxepin as adjunctive therapy for depressed methadone maintenance patients: a double-blind study.
Topics: Adult; Depressive Disorder; Double-Blind Method; Doxepin; Drug Therapy, Combination; Female; Humans; | 1982 |
Psychiatric disorders of opioid addicts entering treatment: preliminary data.
Topics: Adult; Antisocial Personality Disorder; Comorbidity; Cross-Sectional Studies; Depressive Disorder; F | 1994 |
Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence.
Topics: Adult; Amantadine; Antisocial Personality Disorder; Cocaine; Combined Modality Therapy; Comorbidity; | 1994 |
Prognostic factors in Buprenorphine- versus methadone-maintained patients.
Topics: Adult; Alcoholism; Antisocial Personality Disorder; Benzodiazepines; Buprenorphine; Cocaine-Related | 1998 |
Imipramine treatment of opiate-dependent patients with depressive disorders. A placebo-controlled trial.
Topics: Adult; Comorbidity; Depressive Disorder; Diagnosis, Dual (Psychiatry); Double-Blind Method; Drug The | 1998 |
Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts.
Topics: Adult; Antidepressive Agents, Second-Generation; Behavior, Addictive; Cocaine; Cocaine-Related Disor | 1998 |
The autonomy of mood disorders among cocaine-using methadone patients.
Topics: Adult; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Comorb | 1999 |
Oral and intravenous methadone use: some clinical and pharmacokinetic aspects.
Topics: Administration, Oral; Adult; Brief Psychiatric Rating Scale; Depressive Disorder; Dose-Response Rela | 1999 |
The effect of sertraline on methadone plasma levels in methadone-maintenance patients.
Topics: Adult; Depressive Disorder; Double-Blind Method; Drug Interactions; Female; Humans; Male; Methadone; | 2000 |
Sociopathy and psychotherapy outcome.
Topics: Adolescent; Adult; Ambulatory Care; Antisocial Personality Disorder; Counseling; Depressive Disorder | 1985 |
62 other studies available for methadone and Depression, Endogenous
| Article | Year |
|---|---|
Psychopathology and pain correlates of dispositional optimism in methadone-maintained patients.
Topics: Adult; Analgesics, Opioid; Attitude; Chronic Pain; Depressive Disorder; Female; Health Status; Human | 2012 |
Informed consent abandoned--patient given contraindicated drug.
Topics: Alcoholism; Contraindications; Depressive Disorder; Humans; Informed Consent; Male; Medication Recon | 2014 |
[Characteristics of subjects under opiate maintenance treatment in primary care using the OPEMA data 2013].
Topics: Adolescent; Adult; Alcohol Drinking; Anxiety; Benzodiazepines; Buprenorphine; Depressive Disorder; D | 2016 |
The impact of benzodiazepine use on methadone maintenance treatment outcomes.
Topics: Adult; Alcoholism; Benzodiazepines; Cocaine-Related Disorders; Comorbidity; Depressive Disorder; Dia | 2008 |
Affective temperaments in heroin addiction.
Topics: Adult; Alcoholism; Anxiety Disorders; Bipolar Disorder; Cohort Studies; Comorbidity; Cyclothymic Dis | 2009 |
Self-efficacy and depression as mediators of the relationship between pain and antiretroviral adherence.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Depressive Disorder; Female; HIV Infections; Humans; Male; | 2009 |
Adapting problem-solving therapy for depressed older adults in methadone maintenance treatment.
Topics: Aged; Behavior Therapy; Depressive Disorder; Diagnosis, Dual (Psychiatry); Humans; Methadone; Narcot | 2011 |
The effect of methadone on emotional reactivity.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Depressive Disorder; Emotions; Female; Humans; Male; | 2012 |
White matter abnormalities correlating with memory and depression in heroin users under methadone maintenance treatment.
Topics: Adult; Anisotropy; Brain; Brain Mapping; Depressive Disorder; Diffusion Tensor Imaging; Female; Hero | 2012 |
Pain depression and sleep disorders among methadone maintenance treatment patients.
Topics: Adult; Analysis of Variance; Depressive Disorder; Female; Health Status; Humans; Male; Mental Health | 2012 |
The depression of respiration by the opiates and its antagonism by nalorphine.
Topics: Analgesics, Opioid; Depression; Depressive Disorder; Humans; Meperidine; Methadone; Morphine; Nalorp | 1953 |
[Semiquantitative determination of physical dependence in morphine and methadon therapy].
Topics: Depression; Depressive Disorder; Humans; Methadone; Morphine; Morphine Dependence; Substance-Related | 1959 |
Depression and hostility as predictors of long-term outcomes among opiate users.
Topics: Adult; Depressive Disorder; Female; Follow-Up Studies; Hostility; Humans; Male; Methadone; Narcotics | 2004 |
A psychometric study of the prevalence of DSM-IV personality disorders among office-based methadone maintenance patients.
Topics: Adult; Ambulatory Care; Canada; Comorbidity; Depressive Disorder; Diagnostic and Statistical Manual | 2004 |
Dextromethorphan-induced delirium and possible methadone interaction.
Topics: Aged; Analgesics, Opioid; Antitussive Agents; Cough; Delirium; Depressive Disorder; Dextromethorphan | 2005 |
Depression in methadone maintenance treatment patients: rate and risk factors.
Topics: Adult; Benzodiazepines; Brief Psychiatric Rating Scale; Cocaine; Cocaine-Related Disorders; Comorbid | 2007 |
Behavior therapy for depression in drug dependence (BTDD): results of a stage Ia therapy development pilot.
Topics: Behavior Therapy; Combined Modality Therapy; Depressive Disorder; Dysthymic Disorder; Female; Humans | 2006 |
The Beck Depression Inventory in patients undergoing opiate agonist maintenance treatment.
Topics: Adolescent; Adult; Alcoholism; Buprenorphine; Comorbidity; Denmark; Depressive Disorder; Female; Fol | 2006 |
Association between improvement in depression, reduced benzodiazepine (BDZ) abuse, and increased psychotropic medication use in methadone maintenance treatment (MMT) patients.
Topics: Adult; Benzodiazepines; Depressive Disorder; Diagnosis, Dual (Psychiatry); Female; Follow-Up Studies | 2008 |
Tricyclic antidepressants abuse, with or without benzodiazepines abuse, in former heroin addicts currently in methadone maintenance treatment (MMT).
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Benzodiazepines; Cross-Sectional Studies; Da | 2008 |
Behavioral and biological effects of acute beta-endorphin injection in schizophrenic and depressed patients.
Topics: Adult; Depressive Disorder; Double-Blind Method; Endorphins; Female; Humans; Hydrocortisone; Injecti | 1981 |
Depressive symptoms in drug abuse treatment clients: correlates, treatment, and changes.
Topics: Adult; Age Factors; Alcoholism; Ambulatory Care; Depressive Disorder; Female; Heroin Dependence; Hum | 1984 |
Methadone for depression.
Topics: Antidepressive Agents; Depressive Disorder; Humans; Methadone | 1984 |
The dexamethasone suppression test for major depression among opiate addicts.
Topics: Adult; Clonidine; Depressive Disorder; Dexamethasone; Heroin Dependence; Humans; Hydrocortisone; Met | 1984 |
The use of antidepressants with methadone in depressed maintenance patients.
Topics: Depressive Disorder; Doxepin; Female; Humans; Imipramine; Male; Methadone; Middle Aged; Opioid-Relat | 1982 |
Diagnosis and symptoms of depression in opiate addicts. Course and relationship to treatment outcome.
Topics: Adult; Depressive Disorder; Female; Follow-Up Studies; Humans; Male; Methadone; Naltrexone; Opioid-R | 1982 |
Heterogeneity of psychiatric diagnosis in treated opiate addicts.
Topics: Adult; Alcoholism; Anxiety Disorders; Depressive Disorder; Female; Humans; Male; Mental Disorders; M | 1982 |
Blunted prolactin response. A neuroendocrine abnormality manifested by depressed patients.
Topics: Adult; Depressive Disorder; Humans; Hypothalamo-Hypophyseal System; Male; Methadone; Middle Aged; Pr | 1982 |
DSM-III personality type and dose levels in methadone maintenance patients.
Topics: Adult; Depressive Disorder; Dose-Response Relationship, Drug; Female; Humans; Male; Manuals as Topic | 1980 |
Suicidality in a sample of methadone maintenance clients.
Topics: Adult; Anxiety Disorders; Comorbidity; Depressive Disorder; Female; Humans; Male; Methadone; Opioid- | 1995 |
Fluoxetine treatment for dually diagnosed methadone maintained opioid addicts: a pilot study.
Topics: Adult; Cocaine; Combined Modality Therapy; Comorbidity; Depressive Disorder; Diagnosis, Dual (Psychi | 1994 |
[Attempted suicide with a coumarin derivative].
Topics: Adult; Coumarins; Depressive Disorder; Drug Overdose; Heroin Dependence; Humans; Male; Methadone; Pr | 1995 |
Drug use, HIV risk-taking and psychosocial correlates of benzodiazepine use among methadone maintenance clients.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Depressive Disorder; Diagnosis, Dual (Psych | 1993 |
Methadone maintenance outcome as a function of detoxification phobia.
Topics: Adult; Age Factors; Aged; Anxiety Disorders; Attitude to Health; Comorbidity; Depressive Disorder; E | 1994 |
Psychiatric distress in antisocial drug abusers: relation to other personality disorders.
Topics: Adult; Antisocial Personality Disorder; Anxiety Disorders; Combined Modality Therapy; Comorbidity; D | 1994 |
Children of substance abusers: the life experiences of children of opiate addicts in methadone maintenance.
Topics: Adolescent; Adult; Antisocial Personality Disorder; Bipolar Disorder; Child; Child Abuse; Child Abus | 1994 |
Probable metabolic interaction between methadone and fluvoxamine in addict patients.
Topics: Adult; Depressive Disorder; Drug Interactions; Female; Fluvoxamine; Humans; Male; Methadone; Opioid- | 1994 |
Prevalence, severity and correlates of psychological morbidity among methadone maintenance clients.
Topics: Adolescent; Adult; Antisocial Personality Disorder; Anxiety Disorders; Comorbidity; Cross-Sectional | 1994 |
The acute effects of a rapid medical detoxification upon dysphoria and other psychopathology experienced by heroin abusers.
Topics: Adult; Cocaine; Comorbidity; Depressive Disorder; Heroin Dependence; Hospitalization; Humans; Male; | 1994 |
Vulnerability to fluoxetine-induced indifference syndrome among opiate addicts: a case report.
Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Fluoxetine; Humans; Male; Meth | 1995 |
Evidence for response set effects in structured research interviews.
Topics: Adult; Defense Mechanisms; Depressive Disorder; Female; Heroin Dependence; Humans; Male; Malingering | 1996 |
Assessment of object relations and reality testing in methadone patients.
Topics: Adult; Anxiety Disorders; Comorbidity; Depressive Disorder; Female; Heroin Dependence; Humans; Male; | 1996 |
Buprenorphine for depression: the un-adoptable orphan.
Topics: Administration, Intranasal; Administration, Sublingual; Antidepressive Agents; Buprenorphine; Depres | 1996 |
[Depressive disorders in management of drug dependent patients. Methadone maintenance].
Topics: Adult; Antidepressive Agents; Comorbidity; Depressive Disorder; Drug Interactions; Drug Therapy, Com | 1995 |
Response to methadone maintenance and counseling in antisocial patients with and without major depression.
Topics: Antisocial Personality Disorder; Comorbidity; Counseling; Depressive Disorder; Follow-Up Studies; Ho | 1996 |
Psychiatric severity and treatment response in a comprehensive methadone maintenance treatment program.
Topics: Adult; Combined Modality Therapy; Depressive Disorder; Female; Humans; Male; Methadone; Narcotics; P | 1997 |
Treatment of depressed methadone maintenance patients with nefazodone. A case series.
Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Female; Humans; Male; Methadon | 1998 |
Fluvoxamine-methadone interaction.
Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Drug Interactions; Female; Flu | 1999 |
[Acute methadone poisoning].
Topics: Acute Disease; Adult; Depressive Disorder; Humans; Male; Methadone; Naloxone; Narcotic Antagonists; | 2000 |
Depressive disorders and personality variables in HIV positive and negative intravenous drug-users.
Topics: Adult; Comorbidity; Depressive Disorder; Female; HIV Seronegativity; HIV Seropositivity; Humans; Ita | 2001 |
Paroxetine increases steady-state concentrations of (R)-methadone in CYP2D6 extensive but not poor metabolizers.
Topics: Adult; Cytochrome P-450 CYP2D6 Inhibitors; Depressive Disorder; Drug Interactions; Drug Therapy, Com | 2002 |
Sexual dysfunction and psychological distress in methadone maintenance.
Topics: Adult; Anxiety Disorders; Depressive Disorder; Female; Humans; Hyperprolactinemia; Male; Methadone; | 1992 |
Chronic facial pain together with severe depression is responsive to electroconvulsive therapy. A case report.
Topics: Amitriptyline; Chronic Disease; Clonazepam; Depressive Disorder; Electroconvulsive Therapy; Facial P | 1992 |
Early treatment time course of depressive symptoms in opiate addicts.
Topics: Adult; Black or African American; Depression; Depressive Disorder; Female; Follow-Up Studies; Humans | 1991 |
Imipramine treatment of methadone maintenance patients with affective disorder and illicit drug use.
Topics: Adult; Cocaine; Depressive Disorder; Drug Therapy, Combination; Female; Heroin Dependence; Humans; I | 1991 |
Clustering of multiple substance use and psychiatric diagnoses in opiate addicts.
Topics: Adult; Antisocial Personality Disorder; Anxiety Disorders; Cluster Analysis; Cross-Sectional Studies | 1991 |
Psychopathology in Dutch and American heroin addicts.
Topics: Adult; Anxiety Disorders; Cross-Cultural Comparison; Depressive Disorder; Heroin Dependence; Hospita | 1990 |
Evidence for altered desipramine disposition in methadone-maintained patients treated for cocaine abuse.
Topics: Adult; Cocaine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; | 1990 |
Depressive symptoms during buprenorphine treatment of opioid abusers.
Topics: Adult; Buprenorphine; Cocaine; Combined Modality Therapy; Depressive Disorder; Female; Follow-Up Stu | 1990 |
Naloxone challenge as a biological predictor of treatment outcome in opiate addicts.
Topics: Arousal; Depressive Disorder; Humans; Methadone; Naloxone; Opioid-Related Disorders; Personality Tes | 1989 |
[Detoxication or physical weaning].
Topics: Clonidine; Depressive Disorder; Heroin Dependence; Humans; Methadone; Substance Withdrawal Syndrome | 1987 |
A 2.5-year follow-up of cocaine use among treated opioid addicts. Have our treatments helped?
Topics: Adult; Cocaine; Connecticut; Depressive Disorder; Ethnicity; Female; Follow-Up Studies; Humans; Male | 1987 |