methadone has been researched along with Delirium in 10 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Delirium: A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This prospective study documents the use of methadone as part of an opioid rotation strategy in patients with uncontrolled pain and severe delirium admitted for terminal care to a tertiary cancer palliative care hospital." | 9.11 | Methadone in the treatment of pain and terminal delirum in advanced cancer patients. ( Comfort, C; Kogan, M; Moryl, N; Obbens, E, 2005) |
| "Goals consist of determining 5-year prevalence and recurrence of methadone-related delirium (MRD), along with causes, treatments, and outcomes." | 7.91 | Methadone-Related Delirium: Prevalence, Causes, and Outcomes. ( Batres-Y-Carr, T; Dimitropoulos, E; Kolla, BP; Thuras, P; Westermeyer, J; Yoon, G, 2019) |
| "Vulnerability to delirium was potentially caused by coadministration of methadone, which can inhibit the CYP2D6 isozyme." | 7.73 | Dextromethorphan-induced delirium and possible methadone interaction. ( Lotrich, FE; Pollock, BG; Rosen, J, 2005) |
| "This prospective study documents the use of methadone as part of an opioid rotation strategy in patients with uncontrolled pain and severe delirium admitted for terminal care to a tertiary cancer palliative care hospital." | 5.11 | Methadone in the treatment of pain and terminal delirum in advanced cancer patients. ( Comfort, C; Kogan, M; Moryl, N; Obbens, E, 2005) |
| "Goals consist of determining 5-year prevalence and recurrence of methadone-related delirium (MRD), along with causes, treatments, and outcomes." | 3.91 | Methadone-Related Delirium: Prevalence, Causes, and Outcomes. ( Batres-Y-Carr, T; Dimitropoulos, E; Kolla, BP; Thuras, P; Westermeyer, J; Yoon, G, 2019) |
| "Vulnerability to delirium was potentially caused by coadministration of methadone, which can inhibit the CYP2D6 isozyme." | 3.73 | Dextromethorphan-induced delirium and possible methadone interaction. ( Lotrich, FE; Pollock, BG; Rosen, J, 2005) |
| "Methadone is a synthetic opioid analgesic with potential advantages over other commonly used opioids." | 2.53 | Methadone analgesia in the critically ill. ( Elefritz, JL; Lyaker, MR; Murphy, CV; Papadimos, TJ, 2016) |
| "Infant delirium is an under-recognized clinical entity in neonatal intensive care, and earlier identification and treatment could minimize morbidities associated with this condition." | 1.46 | A case of infant delirium in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikegaki, J | 1 |
| Kizawa, Y | 1 |
| Westermeyer, J | 1 |
| Thuras, P | 1 |
| Yoon, G | 1 |
| Kolla, BP | 1 |
| Batres-Y-Carr, T | 1 |
| Dimitropoulos, E | 1 |
| Elefritz, JL | 1 |
| Murphy, CV | 1 |
| Papadimos, TJ | 1 |
| Lyaker, MR | 1 |
| Edwards, LE | 1 |
| Hutchison, LB | 1 |
| Hornik, CD | 1 |
| Smith, PB | 1 |
| Cotten, CM | 1 |
| Bidegain, M | 1 |
| Yennurajalingam, S | 1 |
| Braiteh, F | 1 |
| Bruera, E | 1 |
| Lotrich, FE | 1 |
| Rosen, J | 1 |
| Pollock, BG | 1 |
| Moryl, N | 1 |
| Kogan, M | 1 |
| Comfort, C | 1 |
| Obbens, E | 1 |
| del Rosario, MA | 1 |
| Feria, M | 1 |
| Martín, AS | 1 |
| Ortega, JJ | 1 |
| del Castillo, LP | 1 |
| Vielvoye-Kerkmeer, AP | 1 |
| van der Weide, M | 1 |
| Maxmen, JS | 1 |
| Silberfarb, PM | 1 |
| Plakun, E | 1 |
2 reviews available for methadone and Delirium
| Article | Year |
|---|---|
Methadone analgesia in the critically ill.
Topics: Adult; Analgesics, Opioid; Child; Critical Illness; Delirium; Humans; Intensive Care Units; Methadon | 2016 |
Pain and terminal delirium research in the elderly.
Topics: Aged; Algorithms; Analgesics, Opioid; Anti-Infective Agents; Constipation; Delirium; Drug Interactio | 2005 |
1 trial available for methadone and Delirium
| Article | Year |
|---|---|
Methadone in the treatment of pain and terminal delirum in advanced cancer patients.
Topics: Aged; Analgesics, Opioid; Delirium; Dose-Response Relationship, Drug; Drug Administration Schedule; | 2005 |
7 other studies available for methadone and Delirium
| Article | Year |
|---|---|
Delirium Prolonged for Three Days after Addition of One Dose of 5 mg Methadone to Ongoing Opioid.
Topics: Analgesics, Opioid; Delirium; Dose-Response Relationship, Drug; Humans; Longitudinal Studies; Methad | 2020 |
Methadone-Related Delirium: Prevalence, Causes, and Outcomes.
Topics: Adult; Aged; Analgesics, Opioid; Delirium; Dose-Response Relationship, Drug; Female; Humans; Male; M | 2019 |
A case of infant delirium in the neonatal intensive care unit.
Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acid | 2017 |
Dextromethorphan-induced delirium and possible methadone interaction.
Topics: Aged; Analgesics, Opioid; Antitussive Agents; Cough; Delirium; Depressive Disorder; Dextromethorphan | 2005 |
Reversible delirium during opiod switching from transdermal fentanyl to methadone.
Topics: Administration, Cutaneous; Analgesics, Opioid; Delirium; Fentanyl; Humans; Male; Methadone; Middle A | 2001 |
Re: Reversible delirium during opioid switching.
Topics: Analgesics, Opioid; Delirium; Fentanyl; Humans; Methadone | 2001 |
Pentazocine abuse and problems of withdrawal.
Topics: Antipsychotic Agents; Confusion; Delirium; Dose-Response Relationship, Drug; Female; Humans; Hypnoti | 1975 |