methadone has been researched along with Constricted Pupil in 3 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methadone effects were measured by miosis and thermal analgesia (maximally tolerated temperature and verbal analog scale rating of discreet temperatures)." | 1.40 | Cyclosporine-inhibitable cerebral drug transport does not influence clinical methadone pharmacodynamics. ( Blood, J; Francis, AM; Kharasch, ED; Meissner, K; Yermolenka, V, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meissner, K | 1 |
| Blood, J | 1 |
| Francis, AM | 1 |
| Yermolenka, V | 1 |
| Kharasch, ED | 1 |
| Murillo, R | 1 |
| Crucilla, C | 1 |
| Schmittner, J | 1 |
| Hotchkiss, E | 1 |
| Pickworth, WB | 1 |
| Weinhold, LL | 1 |
| Bigelow, GE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of an Eye Tracking Sensor to Detect Cannabis Impairment[NCT03994926] | Early Phase 1 | 3 participants (Actual) | Interventional | 2020-02-03 | Terminated (stopped due to COVID-19 Pandmic halted study) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for methadone and Constricted Pupil
| Article | Year |
|---|---|
Cyclosporine-inhibitable cerebral drug transport does not influence clinical methadone pharmacodynamics.
Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; ATP Binding Cassette Transporter, Subfa | 2014 |
Pupillometry in the detection of concomitant drug use in opioid-maintained patients.
Topics: Adult; Biometry; Buprenorphine; Diagnostic Techniques, Ophthalmological; Drug Interactions; Female; | 2004 |
Factors influencing assessment of opioid miosis in humans.
Topics: Humans; Light; Methadone; Miosis; Narcotics; Pupil | 1990 |