Page last updated: 2024-10-30

methadone and Cognitive Decline

methadone has been researched along with Cognitive Decline in 4 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Research Excerpts

ExcerptRelevanceReference
"Here, we report a patient who developed acute bilateral hearing loss, ataxia and paraparesis subsequently to intravenous methadone-abuse."4.02Intravenous methadone causes acute toxic and delayed inflammatory encephalopathy with persistent neurocognitive impairments. ( Haessner, S; Johnen, A; Landmeyer, NC; Meyer Zu Hörste, G; Pawlitzki, M; Repple, J; Schulte-Mecklenbeck, A; Wiendl, H, 2021)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Nelson, LF1
Yocum, VK1
Patel, KD1
Qeadan, F1
Hsi, A1
Weitzen, S1
Akbari, P1
Najafi, M1
Rezaei, AM1
Miladi-Gorji, H1
Repple, J1
Haessner, S1
Johnen, A1
Landmeyer, NC1
Schulte-Mecklenbeck, A1
Pawlitzki, M1
Wiendl, H1
Meyer Zu Hörste, G1
Copenhaver, M1
Shrestha, R1
Wickersham, JA1
Weikum, D1
Altice, FL1

Reviews

1 review available for methadone and Cognitive Decline

ArticleYear
Cognitive Outcomes of Young Children After Prenatal Exposure to Medications for Opioid Use Disorder: A Systematic Review and Meta-analysis.
    JAMA network open, 2020, 03-02, Volume: 3, Issue:3

    Topics: Analgesics, Opioid; Buprenorphine; Child Development; Child, Preschool; Cognition; Cognitive Dysfunc

2020

Other Studies

3 other studies available for methadone and Cognitive Decline

ArticleYear
Enriched Environment Ameliorates Cognitive Deficits and Locomotor Sensitization in Morphine-Withdrawn Rats Receiving Methadone Maintenance Treatment.
    Neuropsychobiology, 2020, Volume: 79, Issue:6

    Topics: Animals; Cognitive Dysfunction; Locomotion; Male; Methadone; Morphine; Narcotics; Opiate Substitutio

2020
Intravenous methadone causes acute toxic and delayed inflammatory encephalopathy with persistent neurocognitive impairments.
    BMC neurology, 2021, Feb-22, Volume: 21, Issue:1

    Topics: Administration, Intravenous; Analgesics, Opioid; Ataxia; Brain; Brain Diseases; Brain Edema; Cogniti

2021
An Exploratory Factor Analysis of a Brief Self-Report Scale to Detect Neurocognitive Impairment Among Participants Enrolled in Methadone Maintenance Therapy.
    Journal of substance abuse treatment, 2016, Volume: 63

    Topics: Adult; Cognitive Dysfunction; Factor Analysis, Statistical; Female; Humans; Male; Methadone; Neurops

2016