methadone has been researched along with Cocaine Abuse in 282 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " One of the most efficacious treatments for cocaine abuse is contingency management (CM), but little research has explored the impact of AD on abstinence outcomes, particularly among patients in methadone maintenance." | 9.15 | Concurrent alcohol dependence among methadone-maintained cocaine abusers is associated with greater abstinence. ( Byrne, SA; Petry, NM, 2011) |
| "This 13-week, randomized, double-blind, placebo-controlled trial evaluated the efficacy of desipramine hydrochloride (0 or 150 mg/d) plus buprenorphine hydrochloride (12 mg/d) or methadone hydrochloride (65 mg/d) in 180 opioid-dependent cocaine abusers (124 men, 56 women)." | 9.09 | Desipramine in opioid-dependent cocaine abusers maintained on buprenorphine vs methadone. ( Feingold, A; Jatlow, P; Kosten, TR; Oliveto, AH; Schottenfeld, R, 1999) |
| "This study tested the effectiveness of fluoxetine as a treatment for depression in a population of methadone-maintained opioid addicts." | 9.08 | Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts. ( Carroll, KM; Gordon, L; Kosten, T; Nich, C; Petrakis, I; Rounsaville, B, 1998) |
| "As CRH-binding protein (CRHBP) SNP rs1500 was associated with reduced cocaine abuse after 1 year in methadone maintenance treatment (MMT) for heroin addiction, we evaluated the association of additional 28 selected SNPs, in 17 stress-related genes, with MMT outcome." | 8.02 | Polymorphisms in Stress-Related Genes Are Associated with Reduced Cocaine Abuse and Longer Retention in Methadone Maintenance Treatment for Opioid Use Disorder. ( Adelson, M; Kreek, MJ; Levran, O; Ott, J; Peles, E; Randesi, M, 2021) |
| "Patients with opioid use disorder maintained on methadone report more chronic pain than the general population." | 7.80 | Severity and interference of chronic pain in methadone-maintained outpatients. ( Brooner, RK; Clark, MR; Dunn, KE, 2014) |
| "Methadone is standard pharmacotherapy for opioid-dependent pregnant women, yet the relationship between maternal methadone dose and neonatal abstinence syndrome (NAS) severity is still unclear." | 7.76 | Prenatal methadone exposure, meconium biomarker concentrations and neonatal abstinence syndrome. ( Choo, RE; Concheiro, M; Elko, A; Gray, TR; Huestis, MA; Jansson, LM; Jones, HE; Williams, E, 2010) |
| " This is a case report of euphoria and choreoathetoid movements both transiently induced by rapid adjustment to the selective mu-opioid receptor agonist methadone in an inpatient previously abusing heroine and cocaine." | 7.70 | Choreoathetoid movements associated with rapid adjustment to methadone. ( Banger, M; Bonnet, U; Gastpar, M; Wolstein, J, 1998) |
| "Disulfiram has been an effective cocaine addiction pharmacotherapy, and one of its possible mechanisms of efficacy is through copper chelation and inhibition of an enzyme involved in catecholamine metabolism, dopamine β-hydroxylase (DβH), which converts dopamine to norepinephrine." | 6.78 | Pharmacogenetic randomized trial for cocaine abuse: disulfiram and dopamine β-hydroxylase. ( Hamon, SC; Harding, MJ; Huang, W; Kosten, TR; Lappalainen, J; Nielsen, DA; Wu, G, 2013) |
| "Disulfiram is a potential cocaine addiction pharmacotherapy." | 6.78 | ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse. ( Hamon, SC; Harding, MJ; Kosten, TR; Nielsen, DA; Spellicy, CJ, 2013) |
| "Disulfiram is a cocaine addiction pharmacotherapy that inhibits dopamine β-hydroxylase (DβH) and reduces norepinephrine production." | 6.78 | Pharmacogenetic randomized trial for cocaine abuse: disulfiram and α1A-adrenoceptor gene variation. ( Hamon, SC; Harding, MJ; Huang, W; Kosten, TR; Nielsen, DA; Shorter, D, 2013) |
| "Methadone is a synthetic opioid frequently used in drug maintenance programs for heroin addicts." | 6.43 | Methadone-induced Torsade de pointes tachycardias. ( Ammann, P; Maeder, M; Osswald, S; Schaer, BA; Sticherling, C, 2005) |
| "Age, and the duration of opioid dependence showed a significant influence on cocaine positive urinalysis." | 5.31 | [Cocaine abuse in maintenance therapy with methadone in narcotic dependent patients]. ( Fischer, G; Kraigher, D; Ortner, R; Peternell, A; Schindler, S; Topitz, A, 2001) |
| "Methadone maintenance for heroin dependence reduces illicit drug use, crime, HIV risk, and death." | 5.17 | A randomized investigation of methadone doses at or over 100 mg/day, combined with contingency management. ( Epstein, DH; Kennedy, AP; Phillips, KA; Preston, KL; Reamer, DA; Schmittner, J, 2013) |
| "Selecting opiate-dependent methadone-maintained cocaine abusers on the basis of their urine toxicology and offering them counselling as a way of reducing their harmful drug use did not prove efficacious." | 5.16 | Non-attendance at counselling therapy in cocaine-using methadone-maintained patients: lessons learnt from an abandoned randomised controlled trial. ( Barry, J; Darker, C; El Hassan, H; Kelly, A; O' Connor, S; Smyth, B; Sweeney, B, 2012) |
| " One of the most efficacious treatments for cocaine abuse is contingency management (CM), but little research has explored the impact of AD on abstinence outcomes, particularly among patients in methadone maintenance." | 5.15 | Concurrent alcohol dependence among methadone-maintained cocaine abusers is associated with greater abstinence. ( Byrne, SA; Petry, NM, 2011) |
| "Methadone-maintained cocaine abusers (N = 78) were randomly assigned to 1 of the following 52-week interventions: (a) usual care only (UC), (b) take-home methadone doses contingent on cocaine- and opiate-negative results (THM), or (c) take-home methadone doses for cocaine- and opiate-negative results and monetary-based vouchers contingent on cocaine-negative urinalysis results (THM + V)." | 5.13 | Abstinence-contingent reinforcement and engagement in non-drug-related activities among illicit drug abusers. ( Badger, GJ; Bigelow, G; Higgins, ST; Rogers, RE; Silverman, K; Stitzer, M; Thomas, CS, 2008) |
| "This study evaluated the efficacy of a contingency management (CM) intervention to promote smoking cessation in methadone-maintained patients." | 5.13 | Voucher-based contingent reinforcement of smoking abstinence among methadone-maintained patients: a pilot study. ( Dunn, KE; Heil, SH; Higgins, ST; Sigmon, SC; Thomas, CS, 2008) |
| " Tiagabine significantly reduced cocaine taking behavior compared to placebo or gabapentin among methadone-stabilized cocaine abusers." | 5.12 | Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients. ( Desai, R; Gonsai, K; González, G; Kosten, TR; Oliveto, A; Poling, J; Sofuoglu, M, 2007) |
| "Effective alternatives to long waiting lists for entry into methadone hydrochloride maintenance treatment are needed to reduce the complications of continuing heroin dependence and to increase methadone treatment entry." | 5.12 | A randomized controlled trial of interim methadone maintenance. ( Battjes, RJ; Brady, JV; Butler, CB; Callaman, JM; Highfield, DA; Jaffe, JH; O'Grady, KE; Rouse, CO; Schwartz, RP, 2006) |
| " To explore the treatment implications of these findings, ketoconazole's (600-900 mg daily) ability to reduce heroin and cocaine use was compared with placebo in 39 methadone maintained patients with a history of cocaine abuse or dependence during a 12-week double blind trial." | 5.10 | Ketoconazole increases cocaine and opioid use in methadone maintained patients. ( Feingold, A; Gonsai, K; Kosten, TR; Oliveto, A; Sevarino, KA, 2002) |
| "This 13-week, randomized, double-blind, placebo-controlled trial evaluated the efficacy of desipramine hydrochloride (0 or 150 mg/d) plus buprenorphine hydrochloride (12 mg/d) or methadone hydrochloride (65 mg/d) in 180 opioid-dependent cocaine abusers (124 men, 56 women)." | 5.09 | Desipramine in opioid-dependent cocaine abusers maintained on buprenorphine vs methadone. ( Feingold, A; Jatlow, P; Kosten, TR; Oliveto, AH; Schottenfeld, R, 1999) |
| "Voucher-based reinforcement of cocaine abstinence has been one of the most effective means of treating cocaine abuse in methadone patients, but it has not been effective in all patients." | 5.09 | Voucher-based reinforcement of cocaine abstinence in treatment-resistant methadone patients: effects of reinforcement magnitude. ( Bigelow, GE; Chutuape, MA; Silverman, K; Stitzer, ML, 1999) |
| "Although methadone maintenance is an effective therapy for heroin dependence, some patients continue to use heroin and may benefit from therapeutic modifications." | 5.09 | Methadone dose increase and abstinence reinforcement for treatment of continued heroin use during methadone maintenance. ( Epstein, DH; Preston, KL; Umbricht, A, 2000) |
| " Recent studies have evaluated disulfiram as a treatment for individuals with comorbid alcohol and cocaine abuse." | 5.09 | Disulfiram treatment for cocaine dependence in methadone-maintained opioid addicts. ( Carroll, KM; Frankforter, T; Gordon, LT; McCance-Katz, EF; Nich, C; Petrakis, IL; Rounsaville, BJ, 2000) |
| "This study tested the effectiveness of fluoxetine as a treatment for depression in a population of methadone-maintained opioid addicts." | 5.08 | Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts. ( Carroll, KM; Gordon, L; Kosten, T; Nich, C; Petrakis, I; Rounsaville, B, 1998) |
| "This manuscript provides an overview of the current scientific literature on the impact of maternal drug use, specifically opioids and cocaine, during pregnancy on the acute and long-term outcomes of infants and toddlers from birth through age 3 years." | 4.86 | Prenatal drug exposure: infant and toddler outcomes. ( Accornero, VH; Bandstra, ES; Mansoor, E; Morrow, CE, 2010) |
| "The results confirm that, in a nonexperimental clinical practice setting, BUP is as effective as methadone in the treatment of heroin dependence, with significantly better opiate abuse control, thus possibly allowing longer and more effective treatment programs with reduced relapse rates." | 4.83 | Multimodal drug addiction treatment: a field comparison of methadone and buprenorphine among heroin- and cocaine-dependent patients. ( Cocchi, L; Corrado, F; Cozzolino, E; De Chiara, M; Guglielmino, L; Marzorati, P; Silenzio, R; Vigezzi, P, 2006) |
| "As CRH-binding protein (CRHBP) SNP rs1500 was associated with reduced cocaine abuse after 1 year in methadone maintenance treatment (MMT) for heroin addiction, we evaluated the association of additional 28 selected SNPs, in 17 stress-related genes, with MMT outcome." | 4.02 | Polymorphisms in Stress-Related Genes Are Associated with Reduced Cocaine Abuse and Longer Retention in Methadone Maintenance Treatment for Opioid Use Disorder. ( Adelson, M; Kreek, MJ; Levran, O; Ott, J; Peles, E; Randesi, M, 2021) |
| "Patients with opioid use disorder maintained on methadone report more chronic pain than the general population." | 3.80 | Severity and interference of chronic pain in methadone-maintained outpatients. ( Brooner, RK; Clark, MR; Dunn, KE, 2014) |
| "The objective of this study was to assess craving and mood related to opioid and cocaine use among asymptomatic hepatitis C virus (HCV)+ and HCV- methadone patients who have not started antiviral treatment." | 3.80 | Substance use and hepatitis C: an ecological momentary assessment study. ( Epstein, DH; Lin, JL; Mezghanni, M; Phillips, KA; Preston, KL; Vahabzadeh, M, 2014) |
| "Methadone is standard pharmacotherapy for opioid-dependent pregnant women, yet the relationship between maternal methadone dose and neonatal abstinence syndrome (NAS) severity is still unclear." | 3.76 | Prenatal methadone exposure, meconium biomarker concentrations and neonatal abstinence syndrome. ( Choo, RE; Concheiro, M; Elko, A; Gray, TR; Huestis, MA; Jansson, LM; Jones, HE; Williams, E, 2010) |
| "A woman with schizophrenia in methadone treatment was admitted for treatment of psychotic symptoms and cocaine addiction." | 3.74 | [Methadone: Medical treatment or dealing?]. ( Hetmar, O; Nielsen, MO, 2008) |
| "Alcohol and cocaine abuse result in unsatisfactory treatment outcomes for heroin and illicit opioid addicts engaged in Methadone Maintenance Treatment Programs (MMTPs)." | 3.74 | Alcohol and cocaine use and abuse among opioid addicts engaged in a methadone maintenance treatment program. ( Lovrecic, M; Maremmani, I; Marini, G; Mellini, A; Pacini, M; Pani, PP; Perugi, G; Shinderman, M, 2007) |
| "Although methadone maintenance is the standard treatment of opiate addiction in pregnancy, opinion as to its utility is divided." | 3.73 | Methadone maintenance program in a Swiss perinatal center: (I): Management and outcome of 89 pregnancies. ( Arlettaz, R; Hebisch, G; Kashiwagi, M; Lauper, U; Zimmermann, R, 2005) |
| " Trading sex for money and perceived chance of getting acquired immunodeficiency syndrome (AIDS) were associated positively with homelessness, while participating in methadone detoxification and methadone maintenance programs seemed to offer some protection from homelessness." | 3.70 | Homelessness and gender in out-of-treatment drug users. ( Cottler, L; Dennis, M; Hoffman, J; Inciardi, J; Leukefeld, C; Logan, TK; Royse, D; Wechsberg, W, 2000) |
| " This is a case report of euphoria and choreoathetoid movements both transiently induced by rapid adjustment to the selective mu-opioid receptor agonist methadone in an inpatient previously abusing heroine and cocaine." | 3.70 | Choreoathetoid movements associated with rapid adjustment to methadone. ( Banger, M; Bonnet, U; Gastpar, M; Wolstein, J, 1998) |
| "Five adult methadone-maintained cocaine abusers." | 3.70 | Effects of "binge" use of intravenous cocaine in methadone-maintained individuals. ( Fischman, MW; Foltin, RW, 1998) |
| "However, alcohol use disorder was significantly associated with HRBS sex subscale scores (t=2." | 2.84 | Alcohol use disorders are associated with increased HIV risk behaviors in cocaine-dependent methadone patients. ( Meredith, SE; Petry, NM; Rash, CJ, 2017) |
| "All patients were scanned prior to treatment for cocaine dependence." | 2.82 | Anticipatory reward processing among cocaine-dependent individuals with and without concurrent methadone-maintenance treatment: Relationship to treatment response. ( Carroll, KM; DeVito, EE; Kober, H; Potenza, MN; Worhunsky, PD; Yip, SW, 2016) |
| " Cognitive testing took place at 2 time points: study weeks 4 through 5 to assess baseline performance and 10 to 13 weeks later to assess performance during stable dosing (300 mg topiramate or placebo)." | 2.80 | Topiramate impairs cognitive function in methadone-maintained individuals with concurrent cocaine dependence. ( Bigelow, GE; Johnson, MW; Mintzer, MZ; Rass, O; Strain, EC; Umbricht, A, 2015) |
| "Topiramate (TOP) is an antiepileptic drug that may have utility in the treatment of cocaine dependence because it enhances the GABAergic system, antagonizes the glutamatergic system, and has been identified by NIDA as one of only a few medications providing a "positive signal" warranting further clinical investigation." | 2.79 | Topiramate for cocaine dependence during methadone maintenance treatment: a randomized controlled trial. ( Bigelow, GE; DeFulio, A; Mintzer, MZ; Peirce, J; Strain, EC; Tompkins, DA; Umbricht, A; Winstanley, EL, 2014) |
| "Disulfiram is a potential cocaine addiction pharmacotherapy." | 2.78 | ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse. ( Hamon, SC; Harding, MJ; Kosten, TR; Nielsen, DA; Spellicy, CJ, 2013) |
| "Disulfiram is a cocaine addiction pharmacotherapy that inhibits dopamine β-hydroxylase (DβH) and reduces norepinephrine production." | 2.78 | Pharmacogenetic randomized trial for cocaine abuse: disulfiram and α1A-adrenoceptor gene variation. ( Hamon, SC; Harding, MJ; Huang, W; Kosten, TR; Nielsen, DA; Shorter, D, 2013) |
| "Disulfiram has been an effective cocaine addiction pharmacotherapy, and one of its possible mechanisms of efficacy is through copper chelation and inhibition of an enzyme involved in catecholamine metabolism, dopamine β-hydroxylase (DβH), which converts dopamine to norepinephrine." | 2.78 | Pharmacogenetic randomized trial for cocaine abuse: disulfiram and dopamine β-hydroxylase. ( Hamon, SC; Harding, MJ; Huang, W; Kosten, TR; Lappalainen, J; Nielsen, DA; Wu, G, 2013) |
| "Disulfiram is a cocaine pharmacotherapy that may act through increasing serotonin, benefiting patients with genetically low serotonin transporter levels (5-HTTLPR, S' allele carriers) and low serotonin synthesis (TPH2, A allele carriers)." | 2.77 | Modifying the role of serotonergic 5-HTTLPR and TPH2 variants on disulfiram treatment of cocaine addiction: a preliminary study. ( Hamon, SC; Harding, MJ; Huang, W; Kosten, TR; Nielsen, DA, 2012) |
| "Fluoxetine was not efficacious in reducing cocaine use in patients dually dependent on cocaine and opioids." | 2.76 | A randomized controlled trial of fluoxetine in the treatment of cocaine dependence among methadone-maintained patients. ( Bigelow, GE; Johnson, RE; Silverman, K; Strain, EC; Winstanley, EL, 2011) |
| "CM appears to be an efficacious treatment for cocaine dependence among methadone maintenance clients, regardless of ethnicity." | 2.74 | Comparable efficacy of contingency management for cocaine dependence among African American, Hispanic, and White methadone maintenance clients. ( Barry, D; Petry, NM; Sullivan, B, 2009) |
| "Methadone maintenance was augmented with cognitive-behavioral therapy (CBT), contingency management (CM), both (CBT+CM), or neither." | 2.72 | Changes in HIV risk behaviors among patients receiving combined pharmacological and behavioral interventions for heroin and cocaine dependence. ( Epstein, DH; Preston, KL; Schroeder, JR; Umbricht, A, 2006) |
| "Mecamylamine was well tolerated, and study retention did not differ by treatment group." | 2.71 | A placebo controlled, double-blind study of mecamylamine treatment for cocaine dependence in patients enrolled in an opiate replacement program. ( Angrist, B; Baker, SA; Elkashef, A; Leiderman, D; Majewska, D; Montgomery, A; O'leary, S; Reid, MS; Robinson, J; Rotrosen, J; Schwartz, M; Stone, J, 2005) |
| " Both dose-response and temporal associations of noncontingent voucher receipt with drug-positive urines were assessed." | 2.71 | Do noncontingent vouchers increase drug use? ( Epstein, DH; Gupman, AE; Preston, KL; Schroeder, JR; Umbricht, A, 2003) |
| "Tiagabine appears to be a promising GABAergic medication that moderately improves cocaine-free urines." | 2.71 | Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study. ( George, TP; Gonsai, K; Gonzalez, G; Kosten, TR; Oliveto, A; Poling, J; Sevarino, K; Sofuoglu, M, 2003) |
| "Methadone-treated subjects remained in treatment significantly longer and achieved significantly longer periods of sustained abstinence and a greater proportion drug-free tests, compared with subjects who received buprenorphine." | 2.71 | Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence. ( Carroll, KM; Chawarski, MC; Kosten, TR; Pakes, JR; Pantalon, MV; Schottenfeld, RS, 2005) |
| "This study evaluated a novel drug abuse treatment, the Therapeutic Workplace." | 2.70 | A reinforcement-based therapeutic workplace for the treatment of drug abuse: six-month abstinence outcomes. ( Bigelow, GE; Robles, E; Silverman, K; Stitzer, ML; Svikis, D, 2001) |
| "Methadone was administered daily." | 2.69 | A comparison of levomethadyl acetate, buprenorphine, and methadone for opioid dependence. ( Bigelow, GE; Chutuape, MA; Johnson, RE; Stitzer, ML; Strain, EC; Walsh, SL, 2000) |
| " Comparisons of physiological and subjective measures collected in agonist exposure sessions indicate that LAAM is not less potent than methadone under acute dosing conditions." | 2.69 | Relative potency of levo-alpha-acetylmethadol and methadone in humans under acute dosing conditions. ( Bigelow, GE; Buchhalter, AR; Eissenberg, T; Stitzer, ML; Walsh, SL, 1999) |
| "This hypothesis predicts that drug abusers should excel on tests of knowledge that is related to their lifestyle." | 2.69 | Forms of knowledge, cognitive impairment and drug abuse: a demonstration. ( Beatty, WW; Borrell, GK, 2000) |
| "Co-occurring stimulant/opioid use disorder is an important problem for targeting future research." | 2.66 | A systematic review and meta-analysis of medications for stimulant use disorders in patients with co-occurring opioid use disorders. ( Ayers, C; Chan, B; Freeman, M; Kansagara, D; Kondo, K; Korthuis, PT; Paynter, R, 2020) |
| "There is no FDA-approved medication for treating cocaine dependence." | 2.50 | Mixed κ/μ partial opioid agonists as potential treatments for cocaine dependence. ( Bidlack, JM, 2014) |
| "Methadone is a synthetic opioid frequently used in drug maintenance programs for heroin addicts." | 2.43 | Methadone-induced Torsade de pointes tachycardias. ( Ammann, P; Maeder, M; Osswald, S; Schaer, BA; Sticherling, C, 2005) |
| "Treatment of cocaine addiction includes anti-craving agents, dopamine agonists or blocking agents, antidepressants, and treatment of co-morbid psychiatric disorders, but all with mixed results." | 2.42 | Pharmacologic treatments for heroin and cocaine dependence. ( Kleber, HD, 2003) |
| "Many people being treated for opioid use disorder continue to use drugs during treatment." | 1.56 | Beyond abstinence and relapse: cluster analysis of drug-use patterns during treatment as an outcome measure for clinical trials. ( Bertz, JW; Burgess-Hull, AJ; Epstein, DH; Kowalczyk, WJ; Panlilio, LV; Phillips, KA; Preston, KL; Stull, SW, 2020) |
| "Methadone maintenance is an effective treatment for opioid use disorder (OUD), yet many methadone-maintained patients (MMPs) struggle with cocaine use during OUD recovery." | 1.51 | Increased neural activity in the right dorsolateral prefrontal cortex during a risky decision-making task is associated with cocaine use in methadone-maintained patients. ( Ayaz, H; Brooner, RK; Dunn, KE; Huhn, AS; Sweeney, MM; Yip, SW, 2019) |
| "Alcohol drinking was also associated with higher craving ratings and prestudy alcohol use." | 1.43 | Real-time assessment of alcohol drinking and drug use in opioid-dependent polydrug users. ( Epstein, DH; Jobes, ML; Phillips, KA; Preston, KL, 2016) |
| "To test if polysubstance use profiles and drug-related outcomes differ between those receiving and not receiving opioid substitution therapies (OST) among people who inject drugs (PWID)." | 1.43 | Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies. ( Alati, R; Betts, KS; Burns, L; Chan, G; Dietze, P; McIlwraith, F; Whittaker, E, 2016) |
| " Clinical predictor variables included average methadone dosage (mg/d) and urinalysis drug screen (UDS) findings for opioids and various nonopioid substances at intake and 6 months." | 1.42 | Predictors of patient retention in methadone maintenance treatment. ( Copeland, AL; Herschman, PL; Hoffmann, NG; Kopak, AM; Polukhina, N; Proctor, SL, 2015) |
| "heroin) use disorder." | 1.42 | Impact of incarceration on rates of methadone use in a community recruited cohort of injection drug users. ( Bach, P; Hayashi, K; Kerr, T; Koehn, JD; Milloy, MJ; Nguyen, P; Rieb, L; Wood, E, 2015) |
| "5, 1, 2, and 24 hours after dosing in subjects with confirmed cocaine use and abstinence." | 1.42 | The impact of recent cocaine use on plasma levels of methadone and buprenorphine in patients with and without HIV-infection. ( DInh, AT; Fiellin, DA; Fiellin, LE; Lruie, BS; McCance-Katz, EF; Moody, DE; Tetrault, JM, 2015) |
| " For analysis of the prescribed methadone dose distribution, the patient sample was split into three methadone dosage groups: a low dose group (LDG) (n = 200; < 60 mg/day), a medium dose group (MDG) (n = 273; 60 to 100 mg/day), and a high dose group (HDG) (n = 140; > 100 mg/day)." | 1.40 | Association between methadone dose and concomitant cocaine use in methadone maintenance treatment: a register-based study. ( Baumeister, M; Dürsteler-MacFarland, KM; Gerhard, U; Petitjean, SA; Strasser, J; Vogel, M; Walter, M; Wiesbeck, GA, 2014) |
| "Opioid dependence is growing at an alarming rate in the United States, and opioid dependent patients have substantial medical, as well as psychiatric, conditions that impact their ability to work." | 1.39 | Antisocial personality disorder is associated with receipt of physical disability benefits in substance abuse treatment patients. ( Byrne, SA; Cherniack, MG; Petry, NM, 2013) |
| " The objective of this study involving 130 methadone-maintained outpatients receiving VBRT was to investigate whether resets (a) increase risk for adverse events (AEs) and (b) delay return to abstinence in relation to magnitude of voucher reset." | 1.36 | Resets do not appear to increase the rate of adverse events or prolong relapse in voucher-based reinforcement therapy. ( Bresani, E; Carpenedo, CM; Dugosh, KL; Kirby, KC; Rosenwasser, BJ; Versek, BE, 2010) |
| "Methadone was used (71." | 1.35 | Prescription opioid use, misuse, and diversion among street drug users in New York City. ( Davis, WR; Johnson, BD, 2008) |
| "Prevalence of prescription opioid abuse has increased dramatically in recent years in the United States generally, and a similar pattern of increasing prescription opioid use has also been noted among patients seeking treatment for opioid dependence." | 1.35 | Evaluation of ongoing oxycodone abuse among methadone-maintained patients. ( Dunn, KE; Heil, SH; Higgins, ST; McGee, MR; Sigmon, SC, 2008) |
| "Methadone dosing has been an issue of controversy among clinicians for a long time." | 1.35 | High dose versus moderate dose methadone maintenance: is there a better outcome? ( Amar, R; Casarella, J; Drexler, K; Fareed, A; Roberts, M; Sleboda, M; Vayalapalli, S, 2009) |
| "Secondary data on substance abuse treatment admissions, from 1995 through 2000, were obtained from the Department of Public Health, Community Substance Abuse Services, San Francisco, California." | 1.35 | Investigating the effects of San Francisco's Treatment on Demand Initiative on a publicly-funded substance abuse treatment system: a time series analysis. ( Davis, T; Gleghorn, A; Guydish, J; Sears, C, 2009) |
| "Methadone adherence was calculated as the fraction of days methadone was administered." | 1.34 | The impact of ongoing illicit drug use on methadone adherence in illicit drug users receiving treatment for HIV in a directly observed therapy program. ( Conway, B; DeVlaming, S; Duncan, F; Grebely, J; Khara, M; McLean, M; Mead, A; Petkau, AJ; Raffa, JD; Tossonian, H; Viljoen, M; Wong, T, 2007) |
| "Similarly, the impact of cocaine abuse on psychiatric and social function in subjects already affected by opioid addiction is still poorly understood and further studies are necessary to investigate this specific area that could profoundly affect methadone maintenance treatment." | 1.33 | Comparison between heroin and heroin-cocaine polyabusers: a psychopathological study. ( Bandettini Di Poggio, A; Fornai, F; Maremmani, I; Pacini, M; Paparelli, A; Perugi, G, 2006) |
| "Urine samples were analyzed for drug abuse after one month and after one year." | 1.33 | Gender differences and pregnant women in a methadone maintenance treatment (MMT) clinic. ( Adelson, M; Peles, E, 2006) |
| "Methadone dose was highest in 31 patients who stopped cocaine (176." | 1.33 | High methadone dose significantly reduces cocaine use in methadone maintenance treatment (MMT) patients. ( Adelson, M; Kellogg, S; Kreek, MJ; Peles, E, 2006) |
| "Influence of parental alcohol/substance abuse on methadone maintenance therapy (MMT) outcome was examined in 164 DSM-III-R opioid dependent adults with no other current DSM Axis I disorder." | 1.31 | Family history influence on drug abuse severity and treatment outcome. ( Gupman, AE; Johnson, EO; Miles, DR; Newlin, DB; Pickens, RW; Preston, KL; Soriano, J; Umbricht, A; van den Bree, MB, 2001) |
| "Age, and the duration of opioid dependence showed a significant influence on cocaine positive urinalysis." | 1.31 | [Cocaine abuse in maintenance therapy with methadone in narcotic dependent patients]. ( Fischer, G; Kraigher, D; Ortner, R; Peternell, A; Schindler, S; Topitz, A, 2001) |
| "Long-term drug abuse detrimentally affects the stomatognathic system, as expressed in a high prevalence of oral motor behavior and signs and symptoms of TMD." | 1.31 | Oral motor parafunctions among heavy drug addicts and their effects on signs and symptoms of temporomandibular disorders. ( Gavish, A; Gazit, E; Halachmi, M; Volfin, G; Winocur, E, 2001) |
| "Occurrence of trauma or PTSD did not predict drop-out rates." | 1.31 | Posttraumatic stress disorder and short-term outcome in early methadone treatment. ( Fraser, D; Hien, DA; Levin, FR; Nunes, E, 2000) |
| "Working from the AIDS risk reduction model and other theories of behavior change, we tested psychosocial antecedents of needle/syringe disinfection by 136 injection drug users." | 1.30 | Psychosocial antecedents of needle/syringe disinfection by drug users: a theory-based prospective analysis. ( Anglin, MD; Longshore, D; Stein, JA, 1997) |
| "To evaluate the Methadone Dispensing Circuit in Amsterdam by identifying determinants of methadone dosage and client characteristics in the different types of methadone programmes." | 1.30 | Differentiation in the Amsterdam methadone dispensing circuit: determinants of methadone dosage and site of methadone prescription. ( Coutinho, RA; Langendam, MW; Reurs, H; van Ameijden, EJ; van Brussel, GH; van den Hoek, AA; van Haastrecht, HJ, 1998) |
| "Women with ASPD were unlikely to have alcohol use disorder, but likely to have opioid use disorder." | 1.30 | Gender differences in psychiatric comorbidity among cocaine-using opiate addicts. ( Foote, J; Handelsman, L; Kang, SY; Magura, S; Rosenblum, A, 1998) |
| "In the national Drug Abuse Treatment Outcome Studies (DATOS), many clients in outpatient methadone treatment (OMT) and outpatient drug-free (ODF) modalities were admitted with multiple sex and needle-risk behaviors, but they reduced these risks significantly during treatment." | 1.30 | HIV risk reduction in outpatient drug abuse treatment: individual and geographic differences. ( Broome, KM; Joe, GW; Simpson, DD, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 33 (11.70) | 18.2507 |
| 2000's | 151 (53.55) | 29.6817 |
| 2010's | 87 (30.85) | 24.3611 |
| 2020's | 11 (3.90) | 2.80 |
| Authors | Studies |
|---|---|
| Ginley, MK | 2 |
| Kelly, LM | 1 |
| Pfund, RA | 1 |
| Rash, CJ | 5 |
| Alessi, SM | 3 |
| Zajac, K | 1 |
| Ware, OD | 1 |
| Sweeney, MM | 2 |
| Cunningham, C | 1 |
| Umbricht, A | 12 |
| Stitzer, M | 3 |
| Dunn, KE | 5 |
| Huhn, AS | 1 |
| Brooner, RK | 5 |
| Yip, SW | 3 |
| Ayaz, H | 1 |
| Holtyn, AF | 3 |
| Toegel, F | 1 |
| Subramaniam, S | 1 |
| Jarvis, BP | 1 |
| Leoutsakos, JM | 2 |
| Fingerhood, M | 3 |
| Silverman, K | 23 |
| Rodríguez Mega, E | 1 |
| Roos, CR | 1 |
| Kiluk, BD | 3 |
| McHugh, RK | 1 |
| Carroll, KM | 19 |
| Chan, B | 1 |
| Freeman, M | 1 |
| Ayers, C | 1 |
| Korthuis, PT | 1 |
| Paynter, R | 1 |
| Kondo, K | 1 |
| Kansagara, D | 1 |
| Panlilio, LV | 2 |
| Stull, SW | 2 |
| Bertz, JW | 2 |
| Burgess-Hull, AJ | 2 |
| Kowalczyk, WJ | 2 |
| Phillips, KA | 10 |
| Epstein, DH | 27 |
| Preston, KL | 34 |
| Schwartz, RP | 11 |
| Kelly, SM | 4 |
| Mitchell, SG | 2 |
| O'Grady, KE | 9 |
| Duren, T | 1 |
| Sharma, A | 1 |
| Gryczynski, J | 1 |
| Jaffe, JH | 6 |
| Peles, E | 4 |
| Levran, O | 3 |
| Randesi, M | 1 |
| Ott, J | 1 |
| Kreek, MJ | 11 |
| Adelson, M | 4 |
| Lanza, ST | 1 |
| Curtis, BL | 1 |
| Thomas, PS | 1 |
| Nielsen, EM | 1 |
| Spellicy, CJ | 2 |
| Harding, MJ | 5 |
| Ye, A | 1 |
| Patriquin, M | 1 |
| Hamon, SC | 5 |
| Kosten, TR | 19 |
| Nielsen, DA | 7 |
| Olmstead, TA | 1 |
| Petry, NM | 18 |
| DeVito, EE | 4 |
| Buck, MB | 1 |
| Hunkele, K | 3 |
| Nich, C | 10 |
| Heidebrecht, F | 1 |
| MacLeod, MB | 1 |
| Dawkins, L | 1 |
| Meredith, SE | 1 |
| Holt, SR | 1 |
| Donroe, JH | 1 |
| Cavallo, DA | 1 |
| Tetrault, JM | 2 |
| Smyth, BP | 1 |
| Elmusharaf, K | 1 |
| Cullen, W | 1 |
| Kober, H | 2 |
| Potenza, MN | 3 |
| Lister, JJ | 1 |
| Brown, S | 1 |
| Greenwald, MK | 3 |
| Ledgerwood, DM | 3 |
| Jordan, CJ | 1 |
| Cao, J | 1 |
| Newman, AH | 1 |
| Xi, ZX | 2 |
| Sofuoglu, M | 7 |
| Gardner, RA | 1 |
| Shorter, D | 1 |
| Huang, W | 3 |
| Bidlack, JM | 1 |
| Gordon, MA | 1 |
| Portnoy, GA | 1 |
| Marino, DR | 1 |
| Ball, SA | 3 |
| Koffarnus, MN | 2 |
| DeFulio, A | 5 |
| Sigurdsson, SO | 3 |
| Strain, EC | 6 |
| Freedman, R | 1 |
| Clark, MR | 1 |
| Winstanley, EL | 2 |
| Tompkins, DA | 1 |
| Peirce, J | 2 |
| Mintzer, MZ | 3 |
| Bigelow, GE | 12 |
| Vahabzadeh, M | 4 |
| Mezghanni, M | 2 |
| Lin, JL | 4 |
| Barry, D | 4 |
| Metrebian, N | 1 |
| Groshkova, T | 1 |
| Hellier, J | 1 |
| Charles, V | 1 |
| Martin, A | 1 |
| Forzisi, L | 1 |
| Lintzeris, N | 1 |
| Zador, D | 1 |
| Williams, H | 1 |
| Carnwath, T | 1 |
| Mayet, S | 2 |
| Strang, J | 2 |
| Rass, O | 1 |
| Johnson, MW | 1 |
| Baumeister, M | 1 |
| Vogel, M | 1 |
| Dürsteler-MacFarland, KM | 1 |
| Gerhard, U | 1 |
| Strasser, J | 1 |
| Walter, M | 1 |
| Wiesbeck, GA | 1 |
| Petitjean, SA | 1 |
| McCance-Katz, EF | 3 |
| Moody, DE | 1 |
| Fiellin, DA | 2 |
| Lruie, BS | 1 |
| DInh, AT | 1 |
| Fiellin, LE | 1 |
| Falcato, L | 1 |
| Beck, T | 2 |
| Reimer, J | 1 |
| Verthein, U | 1 |
| Koehn, JD | 1 |
| Bach, P | 1 |
| Hayashi, K | 1 |
| Nguyen, P | 2 |
| Kerr, T | 5 |
| Milloy, MJ | 3 |
| Rieb, L | 1 |
| Wood, E | 5 |
| Levine, AR | 1 |
| Lundahl, LH | 1 |
| Lisieski, M | 1 |
| Rhodes, GL | 2 |
| Uhlmann, S | 1 |
| Ahamad, K | 1 |
| Richardson, L | 1 |
| Morie, KP | 1 |
| Proctor, SL | 1 |
| Copeland, AL | 1 |
| Kopak, AM | 1 |
| Hoffmann, NG | 1 |
| Herschman, PL | 1 |
| Polukhina, N | 1 |
| Burch, AE | 1 |
| Willner-Reid, J | 2 |
| Whitaker, D | 1 |
| Pulaski, AR | 1 |
| Willner, P | 1 |
| Kim, SJ | 1 |
| Marsch, LA | 1 |
| Acosta, MC | 1 |
| Guarino, H | 1 |
| Aponte-Melendez, Y | 1 |
| Betts, KS | 1 |
| Chan, G | 1 |
| McIlwraith, F | 1 |
| Dietze, P | 1 |
| Whittaker, E | 1 |
| Burns, L | 1 |
| Alati, R | 1 |
| Roux, P | 1 |
| Lions, C | 1 |
| Vilotitch, A | 1 |
| Michel, L | 1 |
| Mora, M | 1 |
| Maradan, G | 1 |
| Marcellin, F | 1 |
| Spire, B | 1 |
| Morel, A | 1 |
| Carrieri, PM | 1 |
| Blanken, P | 1 |
| Hendriks, VM | 1 |
| Huijsman, IA | 1 |
| van Ree, JM | 1 |
| van den Brink, W | 1 |
| Worhunsky, PD | 1 |
| Jobes, ML | 1 |
| Decker, SE | 1 |
| Morie, K | 1 |
| Babuscio, T | 2 |
| Socías, ME | 1 |
| Small, W | 1 |
| Dong, H | 1 |
| Shoveller, J | 1 |
| Montaner, J | 2 |
| Moran, LM | 1 |
| Ghitza, UE | 4 |
| Agage, DA | 1 |
| Weiss, RD | 1 |
| Poling, J | 7 |
| Gonsai, K | 7 |
| Severino, K | 1 |
| Weinstock, J | 2 |
| Conner, BT | 1 |
| Anglin, MD | 2 |
| Annon, J | 1 |
| Longshore, D | 2 |
| Brands, B | 1 |
| Blake, J | 1 |
| Marsh, DC | 2 |
| Sproule, B | 1 |
| Jeyapalan, R | 1 |
| Li, S | 1 |
| Leri, F | 2 |
| Zhou, Y | 3 |
| Goddard, B | 1 |
| Levy, A | 1 |
| Jacklin, D | 1 |
| Heinz, AJ | 1 |
| Wu, J | 1 |
| Witkiewitz, K | 1 |
| Rogers, RE | 1 |
| Higgins, ST | 4 |
| Thomas, CS | 2 |
| Badger, GJ | 1 |
| Bigelow, G | 4 |
| Nielsen, MO | 1 |
| Hetmar, O | 1 |
| Schmittner, J | 5 |
| Schroeder, JR | 4 |
| Moolchan, ET | 1 |
| Reisinger, HS | 1 |
| Peterson, JA | 1 |
| Agar, MH | 1 |
| Brown, BS | 2 |
| Peirce, JM | 3 |
| Roll, JM | 3 |
| Kolodner, K | 5 |
| Krasnansky, J | 1 |
| Stabile, PQ | 1 |
| Brown, C | 1 |
| Stitzer, ML | 19 |
| Donlin, WD | 1 |
| Knealing, TW | 2 |
| Needham, M | 3 |
| Wong, CJ | 6 |
| Sigmon, SC | 4 |
| Heil, SH | 3 |
| Kirby, KC | 2 |
| Kerwin, ME | 1 |
| Carpenedo, CM | 3 |
| Rosenwasser, BJ | 2 |
| Gardner, RS | 1 |
| Husky, MM | 1 |
| Mazure, CM | 1 |
| Sullivan, B | 1 |
| Kinlock, TW | 2 |
| Gordon, MS | 2 |
| Fitzgerald, TT | 2 |
| Das, B | 1 |
| Highfield, DA | 3 |
| Wilson, ME | 1 |
| Oviedo-Joekes, E | 1 |
| Brissette, S | 1 |
| Lauzon, P | 1 |
| Guh, D | 1 |
| Anis, A | 1 |
| Schechter, MT | 1 |
| Gorelick, DA | 1 |
| Marsden, J | 3 |
| Eastwood, B | 1 |
| Bradbury, C | 1 |
| Dale-Perera, A | 1 |
| Farrell, M | 2 |
| Hammond, P | 1 |
| Knight, J | 1 |
| Randhawa, K | 1 |
| Wright, C | 1 |
| Tzilos, GK | 1 |
| Martell, BA | 1 |
| Orson, FM | 1 |
| Mitchell, E | 1 |
| Rossen, RD | 1 |
| Gardner, T | 1 |
| Marrone, GF | 1 |
| Heishman, SJ | 1 |
| Moffat, R | 1 |
| Sears, C | 1 |
| Davis, T | 1 |
| Guydish, J | 1 |
| Gleghorn, A | 1 |
| Fareed, A | 1 |
| Casarella, J | 1 |
| Roberts, M | 1 |
| Sleboda, M | 1 |
| Amar, R | 1 |
| Vayalapalli, S | 1 |
| Drexler, K | 1 |
| Castells, X | 1 |
| Capellà, D | 1 |
| Vidal, X | 1 |
| Colom, J | 1 |
| Casas, M | 2 |
| Jones, HE | 3 |
| Martin, PR | 1 |
| Kaltenbach, K | 1 |
| Coyle, MG | 1 |
| Stine, SM | 1 |
| Selby, P | 1 |
| Arria, AM | 1 |
| Fischer, G | 2 |
| Jansson, LM | 2 |
| Dipietro, JA | 1 |
| Elko, A | 2 |
| Velez, M | 1 |
| Yuferov, V | 1 |
| Proudnikov, D | 1 |
| Wu, LT | 1 |
| Pan, JJ | 1 |
| Blazer, DG | 1 |
| Tai, B | 1 |
| Woody, GE | 1 |
| Somers, CJ | 1 |
| Bridgeman, J | 1 |
| Keenan, E | 1 |
| Bandstra, ES | 1 |
| Morrow, CE | 1 |
| Mansoor, E | 1 |
| Accornero, VH | 1 |
| Bravo, MJ | 1 |
| Llorens, N | 1 |
| Barrio, G | 1 |
| Brugal, MT | 1 |
| Santos, S | 1 |
| Sordo, L | 1 |
| de la Fuente, L | 1 |
| Versek, BE | 1 |
| Dugosh, KL | 1 |
| Bresani, E | 1 |
| Comiskey, CM | 1 |
| Cox, G | 1 |
| Simkin, DR | 1 |
| Grenoble, S | 1 |
| Peng, XQ | 1 |
| Li, X | 1 |
| Spiller, K | 1 |
| Li, J | 1 |
| Chun, L | 1 |
| Wu, KM | 1 |
| Froimowitz, M | 1 |
| Gardner, EL | 1 |
| Oliveto, A | 7 |
| Mancino, MJ | 1 |
| Feldman, Z | 1 |
| Cubells, JF | 2 |
| Pruzinsky, R | 1 |
| Cargile, C | 1 |
| Chopra, MP | 1 |
| Gonzalez-Haddad, G | 1 |
| Gray, TR | 1 |
| Choo, RE | 1 |
| Concheiro, M | 1 |
| Williams, E | 1 |
| Huestis, MA | 3 |
| Johnson, RE | 2 |
| Gandhi, D | 2 |
| Cone, EJ | 4 |
| Byrne, SA | 2 |
| van Holst, RJ | 1 |
| Schilt, T | 1 |
| Carmichael, B | 1 |
| Cummins, E | 1 |
| Hedrich, D | 1 |
| Alves, P | 1 |
| Stöver, H | 1 |
| Møller, L | 1 |
| Badin de Montjoye, B | 1 |
| Podevin, P | 1 |
| Pharo, P | 1 |
| Darker, C | 1 |
| Sweeney, B | 1 |
| El Hassan, H | 1 |
| Kelly, A | 1 |
| O' Connor, S | 1 |
| Smyth, B | 1 |
| Barry, J | 1 |
| Ho, A | 5 |
| Bahl, A | 1 |
| Varma, P | 1 |
| Kellogg, S | 3 |
| Borg, L | 4 |
| Shi, JM | 1 |
| Eagan, D | 1 |
| Wu, G | 1 |
| Lappalainen, J | 1 |
| Reed, B | 1 |
| Schlussman, SD | 1 |
| Butelman, ER | 1 |
| Kennedy, AP | 2 |
| Reamer, DA | 1 |
| Moore, BA | 1 |
| Fazzino, T | 1 |
| Barry, DT | 1 |
| Cutter, CJ | 1 |
| Schottenfeld, RS | 4 |
| Cherniack, MG | 1 |
| Rawson, RA | 1 |
| Huber, A | 1 |
| McCann, M | 1 |
| Shoptaw, S | 1 |
| Farabee, D | 1 |
| Reiber, C | 1 |
| Ling, W | 1 |
| Magura, S | 8 |
| Rosenblum, A | 6 |
| Fong, C | 2 |
| Villano, C | 1 |
| Richman, B | 1 |
| Seivewright, N | 1 |
| Gossop, M | 3 |
| Stewart, D | 2 |
| Kidd, T | 1 |
| Herning, RI | 1 |
| Better, WE | 1 |
| Tate, K | 1 |
| Cadet, JL | 1 |
| Hawkins, WE | 1 |
| Covi, L | 1 |
| Margolin, A | 7 |
| Kantak, K | 1 |
| Copenhaver, M | 1 |
| Avants, SK | 7 |
| Marcotte, D | 1 |
| Arnold, R | 1 |
| Kleber, HD | 1 |
| Oliveto, AH | 1 |
| Feingold, A | 3 |
| Schottenfeld, R | 3 |
| Jatlow, P | 1 |
| Gupman, AE | 2 |
| Satora, L | 1 |
| Morawska, J | 1 |
| Correia, CJ | 4 |
| Dallery, J | 2 |
| Katz, EC | 2 |
| Gonzalez, G | 4 |
| Sevarino, K | 1 |
| George, TP | 1 |
| Man, LH | 1 |
| Best, D | 1 |
| Stillwell, G | 1 |
| Grella, CE | 1 |
| Hser, YI | 1 |
| Hsieh, SC | 1 |
| Flynn, PM | 1 |
| Joe, GW | 2 |
| Broome, KM | 2 |
| Simpson, DD | 4 |
| Grabowski, J | 3 |
| Rhoades, H | 1 |
| Stotts, A | 1 |
| Cowan, K | 1 |
| Kopecky, C | 1 |
| Dougherty, A | 1 |
| Moeller, FG | 1 |
| Hassan, S | 1 |
| Schmitz, J | 1 |
| Usubiaga, MH | 1 |
| Doebrick, C | 1 |
| Jofre-Bonet, M | 1 |
| Sindelar, JL | 2 |
| Petrakis, IL | 3 |
| Frankforter, T | 2 |
| Rounsaville, BJ | 4 |
| Conway, B | 2 |
| Prasad, J | 1 |
| Reynolds, R | 1 |
| Farley, J | 1 |
| Jones, M | 1 |
| Jutha, S | 1 |
| Smith, N | 1 |
| Mead, A | 2 |
| DeVlaming, S | 2 |
| Krenz, S | 2 |
| Dieckmann, S | 1 |
| Favrat, B | 2 |
| Spagnoli, J | 1 |
| Leutwyler, J | 1 |
| Schnyder, C | 1 |
| Daeppen, JB | 1 |
| Besson, J | 2 |
| Robles, E | 3 |
| Mudric, T | 1 |
| Kidorf, MS | 1 |
| King, VL | 2 |
| Stoller, KB | 1 |
| Cooper, G | 1 |
| Wilson, L | 1 |
| Reid, C | 1 |
| Baldwin, D | 1 |
| Hand, C | 1 |
| Spieher, V | 1 |
| Ledoux, Y | 1 |
| Rayburn, WF | 1 |
| Bogenschutz, MP | 1 |
| Chawarski, MC | 2 |
| Pakes, JR | 2 |
| Pantalon, MV | 2 |
| Kashiwagi, M | 1 |
| Arlettaz, R | 1 |
| Lauper, U | 1 |
| Zimmermann, R | 1 |
| Hebisch, G | 1 |
| Meili, D | 2 |
| Dober, S | 1 |
| Martin, B | 2 |
| Simcic, F | 1 |
| Durst, P | 1 |
| Palazzolo, J | 1 |
| Peyrelong, JP | 1 |
| Berger, M | 1 |
| Chalabreysse, M | 1 |
| Billiard, M | 1 |
| Vialle, A | 1 |
| Verdejo, A | 1 |
| Toribio, I | 1 |
| Orozco, C | 1 |
| Puente, KL | 1 |
| Pérez-García, M | 2 |
| Rowan-Szal, GA | 2 |
| Bartholomew, NG | 1 |
| Chatham, LR | 2 |
| Disney, ER | 1 |
| Kidorf, M | 1 |
| Neufeld, K | 1 |
| Marsh, D | 1 |
| Li, K | 2 |
| Sticherling, C | 1 |
| Schaer, BA | 1 |
| Ammann, P | 1 |
| Maeder, M | 1 |
| Osswald, S | 1 |
| Schmittner, JP | 1 |
| Raby, WN | 1 |
| Carpenter, KM | 1 |
| Aharonovich, E | 1 |
| Rubin, E | 1 |
| Bisaga, A | 1 |
| Levin, F | 1 |
| Nunes, EV | 1 |
| Dobler-Mikola, A | 1 |
| Hättenschwiler, J | 1 |
| Böni, E | 1 |
| Modestin, J | 1 |
| Kolodner, KB | 1 |
| Li, R | 1 |
| Hamilton, JA | 1 |
| Brady, JV | 1 |
| Butler, CB | 1 |
| Rouse, CO | 1 |
| Callaman, JM | 1 |
| Battjes, RJ | 1 |
| Petry, N | 1 |
| Martell, B | 1 |
| Millson, P | 1 |
| Challacombe, L | 1 |
| Villeneuve, PJ | 1 |
| Strike, CJ | 1 |
| Fischer, B | 1 |
| Myers, T | 1 |
| Shore, R | 1 |
| Hopkins, S | 1 |
| Trafton, JA | 2 |
| Minkel, J | 1 |
| Humphreys, K | 2 |
| Maremmani, I | 3 |
| Perugi, G | 3 |
| Pacini, M | 3 |
| Akiskal, HS | 1 |
| Reid, MS | 1 |
| Angrist, B | 1 |
| Baker, SA | 1 |
| O'leary, S | 1 |
| Stone, J | 1 |
| Schwartz, M | 1 |
| Leiderman, D | 1 |
| Montgomery, A | 1 |
| Elkashef, A | 1 |
| Majewska, D | 1 |
| Robinson, J | 1 |
| Rotrosen, J | 1 |
| Johnson, BA | 1 |
| Aouizerate, B | 1 |
| Schluger, JH | 2 |
| Perret, G | 1 |
| Le Moal, M | 1 |
| Piazza, PV | 1 |
| Vigezzi, P | 1 |
| Guglielmino, L | 1 |
| Marzorati, P | 1 |
| Silenzio, R | 1 |
| De Chiara, M | 1 |
| Corrado, F | 1 |
| Cocchi, L | 1 |
| Cozzolino, E | 1 |
| Matthews, AM | 1 |
| Fireman, M | 1 |
| Zucker, B | 1 |
| Sobel, M | 1 |
| Hauser, P | 1 |
| Desai, R | 1 |
| Melia, D | 1 |
| Khuri, E | 1 |
| Lin, A | 1 |
| Schreiber, S | 1 |
| Naumovsky, Y | 1 |
| Brooks, DJ | 1 |
| Vosburg, SK | 1 |
| Evans, SM | 1 |
| Levin, FR | 2 |
| Bandettini Di Poggio, A | 1 |
| Fornai, F | 1 |
| Paparelli, A | 1 |
| Mitcheson, L | 1 |
| McCambridge, J | 1 |
| Byrne, S | 1 |
| Sindelar, J | 1 |
| Elbel, B | 1 |
| Tracy, SW | 1 |
| Oliva, EM | 1 |
| Inciardi, JA | 1 |
| Surratt, HL | 1 |
| Kurtz, SP | 1 |
| Cicero, TJ | 1 |
| Raffa, JD | 1 |
| Grebely, J | 1 |
| Tossonian, H | 1 |
| Wong, T | 1 |
| Viljoen, M | 1 |
| Khara, M | 1 |
| McLean, M | 1 |
| Duncan, F | 1 |
| Petkau, AJ | 1 |
| Pani, PP | 1 |
| Mellini, A | 1 |
| Marini, G | 1 |
| Lovrecic, M | 1 |
| Shinderman, M | 1 |
| Cofrancesco, J | 1 |
| Brown, TT | 1 |
| Luo, RF | 1 |
| John, M | 1 |
| Stewart, KJ | 1 |
| Dobs, AS | 1 |
| O'Grady, K | 1 |
| Wilson, M | 1 |
| Miller, CL | 1 |
| Strathdee, SA | 1 |
| Vandrey, R | 1 |
| De, P | 1 |
| Cox, J | 1 |
| Boivin, JF | 1 |
| Platt, RW | 1 |
| Jolly, AM | 1 |
| Pelet, A | 1 |
| Doll, S | 1 |
| Huissoud, T | 1 |
| Resplendino, J | 1 |
| Davis, WR | 1 |
| Johnson, BD | 1 |
| Diemer, KN | 1 |
| Knealing, T | 1 |
| Crone-Todd, D | 1 |
| Nuzzo, P | 1 |
| Hanson, T | 1 |
| Sierra, S | 1 |
| Zullino, DF | 1 |
| Eap, CB | 1 |
| Benguettat, D | 1 |
| Khan, R | 1 |
| Arasteh, K | 1 |
| Des Jarlais, DC | 2 |
| Perlis, TE | 1 |
| McGee, MR | 1 |
| Aguilar de Arcos, F | 1 |
| Verdejo-García, A | 1 |
| Ceverino, A | 1 |
| Montañez-Pareja, M | 1 |
| López-Juárez, E | 1 |
| Sánchez-Barrera, M | 1 |
| López-Jiménez, A | 1 |
| Stein, JA | 1 |
| DePhilippis, D | 1 |
| Schmitz, JM | 1 |
| Rhoades, HM | 1 |
| Elk, R | 1 |
| Creson, D | 1 |
| Hussein, I | 1 |
| Langendam, MW | 1 |
| van Haastrecht, HJ | 1 |
| van Brussel, GH | 1 |
| Reurs, H | 1 |
| van den Hoek, AA | 1 |
| Coutinho, RA | 1 |
| van Ameijden, EJ | 1 |
| Petrakis, I | 1 |
| Gordon, L | 1 |
| Kosten, T | 1 |
| Rounsaville, B | 1 |
| Nassogne, MC | 1 |
| Gressens, P | 1 |
| Evrard, P | 1 |
| Courtoy, PJ | 1 |
| Montoya, I | 1 |
| Schuster, CR | 2 |
| Foltin, RW | 1 |
| Fischman, MW | 1 |
| Bonnet, U | 1 |
| Banger, M | 1 |
| Wolstein, J | 1 |
| Gastpar, M | 1 |
| Kang, SY | 3 |
| Nwakeze, PC | 2 |
| Demsky, S | 2 |
| Handelsman, L | 3 |
| Foote, J | 3 |
| Umbricht-Schneiter, A | 1 |
| Montoya, ID | 1 |
| Brewer, DD | 1 |
| Fleming, CB | 1 |
| Haggerty, KP | 1 |
| Catalano, RF | 1 |
| Rodriguez, EM | 1 |
| Chutuape, MA | 5 |
| Stine, S | 1 |
| Cooney, NL | 1 |
| Rosenheck, RA | 1 |
| Li, SH | 1 |
| Fallon, B | 1 |
| Bernstein, D | 1 |
| van Brussel, G | 1 |
| Eyler, FD | 1 |
| Behnke, M | 1 |
| Eissenberg, T | 1 |
| Buchhalter, AR | 1 |
| Walsh, SL | 2 |
| Rothbard, A | 1 |
| Alterman, A | 2 |
| Rutherford, M | 2 |
| Liu, F | 1 |
| Zelinski, S | 1 |
| McKay, J | 1 |
| Palij, M | 1 |
| Stimmel, B | 1 |
| Kranzler, HR | 1 |
| Amin, H | 1 |
| Modesto-Lowe, V | 1 |
| Oncken, C | 1 |
| Wasserman, DA | 2 |
| Korcha, R | 1 |
| Havassy, BE | 1 |
| Hall, SM | 1 |
| Goldberger, BA | 1 |
| Merrill, J | 1 |
| Cacciola, J | 1 |
| Broe, DM | 1 |
| Beatty, WW | 1 |
| Borrell, GK | 1 |
| Morral, AR | 1 |
| McCaffrey, D | 1 |
| Iguchi, MY | 1 |
| Katz, E | 1 |
| Chermack, ST | 1 |
| Roll, J | 1 |
| Reilly, M | 1 |
| Davis, L | 1 |
| Kilaru, U | 1 |
| Gordon, LT | 1 |
| Alterman, AI | 1 |
| Shen, Q | 1 |
| Merrill, JC | 1 |
| McLellan, AT | 1 |
| Durell, J | 1 |
| McKay, JR | 1 |
| Pakes, J | 1 |
| Brienza, RS | 1 |
| Stein, MD | 1 |
| Chen, M | 1 |
| Gogineni, A | 1 |
| Sobota, M | 1 |
| Maksad, J | 1 |
| Hu, P | 1 |
| Clarke, J | 1 |
| Royse, D | 1 |
| Leukefeld, C | 1 |
| Logan, TK | 1 |
| Dennis, M | 1 |
| Wechsberg, W | 1 |
| Hoffman, J | 1 |
| Cottler, L | 1 |
| Inciardi, J | 1 |
| Hien, DA | 1 |
| Nunes, E | 1 |
| Fraser, D | 1 |
| DeMaria, PA | 1 |
| Sterling, R | 1 |
| Weinstein, SP | 1 |
| Mckee, S | 1 |
| Fallon, BM | 1 |
| Pickens, RW | 1 |
| Miles, DR | 1 |
| Johnson, EO | 1 |
| Newlin, DB | 1 |
| Soriano, J | 1 |
| van den Bree, MB | 1 |
| Haug, N | 1 |
| Svikis, D | 2 |
| Deren, S | 1 |
| Goldstein, MF | 1 |
| Richman, BL | 1 |
| Kang, S | 1 |
| Flom, PL | 1 |
| Pérez de los Cobos, J | 1 |
| Duro, P | 1 |
| Trujols, J | 1 |
| Tejero, A | 1 |
| Batlle, F | 1 |
| Ribalta, E | 1 |
| Spanbauer, AC | 1 |
| Casseday, S | 1 |
| Davoudzadeh, D | 1 |
| Stewart, AL | 1 |
| Delucchi, KL | 1 |
| Ortner, R | 1 |
| Peternell, A | 1 |
| Kraigher, D | 1 |
| Schindler, S | 1 |
| Topitz, A | 1 |
| Robles-Sotelo, E | 1 |
| Winocur, E | 1 |
| Gavish, A | 1 |
| Volfin, G | 1 |
| Halachmi, M | 1 |
| Gazit, E | 1 |
| Sevarino, KA | 1 |
| Dhopesh, V | 1 |
| Yu, E | 1 |
| Fudala, PJ | 1 |
| Villano, CL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Long-Term Treatment of Drug Addiction and Unemployment[NCT02487745] | 91 participants (Actual) | Interventional | 2015-11-30 | Completed | |||
| A Randomized Trial of Interim Methadone and Patient Navigation Initiated in Jail[NCT02334215] | 225 participants (Actual) | Interventional | 2014-12-15 | Completed | |||
| Effectiveness of Disulfiram for Treating Cocaine Dependence in Individuals With Different Dopamine Beta Hydroxylase (DBH) Genes[NCT00149630] | Phase 2 | 93 participants (Actual) | Interventional | 2005-01-31 | Completed | ||
| Computer-Based Training in Cognitive Behavior Therapy[NCT00350610] | Phase 1 | 100 participants (Actual) | Interventional | 2007-11-30 | Completed | ||
| A Bridge to Treatment: The Therapeutic Workplace and Methadone Treatment[NCT01416584] | 98 participants (Actual) | Interventional | 2008-10-31 | Completed | |||
| Clinical Trial of Topiramate for Cocaine Addiction[NCT00685178] | Phase 2 | 250 participants (Actual) | Interventional | 2007-02-28 | Completed | ||
| Encouraging Abstinence Behavior in a Drug Epidemic[NCT04927143] | Phase 2 | 600 participants (Anticipated) | Interventional | 2021-09-15 | Recruiting | ||
| Randomised, Controlled Clinical Study Regarding the Feasibility of Converting Opiate Dependents From Methadone Substitutes to Slow Release Morphine Sulphate (Sevre-Long™)[NCT01079117] | Phase 3 | 276 participants (Actual) | Interventional | 2006-10-31 | Completed | ||
| Real Time Assessment of Drug Craving, Use, and Abstinence During Outpatient: A Development and Feasibility Study[NCT00292136] | 230 participants (Actual) | Observational | 2003-08-15 | Completed | |||
| Screen, Treat and Retain Meth-using People With Opioid Use Disorders at Methadone Clinics[NCT04706624] | 640 participants (Anticipated) | Interventional | 2020-11-02 | Active, not recruiting | |||
| Initialization of Methadone in Primary Care; a Randomized Intervention Research for Preventing HCV Transmission Practices. ANRS Methaville[NCT00657397] | Phase 3 | 197 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| Peer-Delivered Behavioral Activation Intervention to Improve Adherence to MAT Among Low-Income, Minority Individuals With OUD - Pilot Phase[NCT04248933] | 37 participants (Actual) | Interventional | 2020-10-09 | Completed | |||
| Treating Cocaine Abuse: A Behavioral Approach[NCT01822327] | Phase 2 | 124 participants (Anticipated) | Interventional | 2007-12-31 | Active, not recruiting | ||
| Methadone Maintenance for Prisoners[NCT00378079] | Phase 3 | 211 participants (Actual) | Interventional | 2003-09-30 | Completed | ||
| North American Opiate Medication Initiative (NAOMI): Multi-Centre, Randomized Controlled Trial of Heroin-Assisted Therapy for Treatment-Refractory Injection Opiate Users[NCT00175357] | Phase 3 | 192 participants (Actual) | Interventional | 2005-03-31 | Completed | ||
| SALOME: Multi-Centre, Double Blind Randomized Controlled Trial Comparing The Effectiveness Of Diacetylmorphine Vs. Hydromorphone For The Treatment Of Long-Term Injection Opioid Users Who Do Not Benefit From Available Therapies[NCT01447212] | Phase 3 | 202 participants (Actual) | Interventional | 2011-12-31 | Completed | ||
| A Double-Blind, Randomized, Placebo-Controlled, Multi-Center Study to Assess the Clinical Efficacy, Safety, and Immunogenicity of a Human Cocaine Vaccine (TA-CD) in the Treatment of Cocaine Dependence[NCT00969878] | Phase 2 | 300 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| An Innovative Digital Smoking Cessation Intervention for Low-Income Adults With Substance Use Disorder[NCT04419922] | 100 participants (Actual) | Observational | 2020-04-02 | Active, not recruiting | |||
| A Pilot Randomized Comparative Effectiveness Clinical Trial of Buprenorphine vs. Methadone for the Treatment of Opioid Dependence in Pregnancy.[NCT03098407] | 55 participants (Actual) | Interventional | 2017-04-20 | Completed | |||
| Vagal Tone and Neonatal Abstinence Syndrome[NCT00496951] | 65 participants (Actual) | Observational | 2006-09-30 | Completed | |||
| Therapeutic Workplace Maintenance Study[NCT00249496] | 51 participants (Actual) | Interventional | 2003-10-31 | Completed | |||
| Entry Into Comprehensive Methadone Treatment Via Interim Maintenance[NCT00712036] | 230 participants (Actual) | Interventional | 2008-06-30 | Completed | |||
| Maximizing the Efficacy of Cognitive Behavioral Therapy With Medication and Contingency Management[NCT00350870] | Phase 1 | 181 participants (Actual) | Interventional | 2005-04-30 | Completed | ||
| Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs[NCT03282890] | 237 participants (Actual) | Interventional | 2017-11-20 | Completed | |||
| Secondary HIV Prevention and Adherence Among HIV-infected Drug Users[NCT01741311] | 133 participants (Actual) | Interventional | 2012-09-30 | Completed | |||
| Enhancing Office-based Buprenorphine Treatment: An Adaptive Psychosocial Approach[NCT04650386] | 250 participants (Anticipated) | Interventional | 2020-09-21 | Recruiting | |||
| Encouraging Opioid Abstinence Behavior: Incentivizing Inputs and Outcomes - Pilot[NCT04235582] | 36 participants (Actual) | Interventional | 2020-08-25 | Completed | |||
| Encouraging Abstinence Behavior in a Drug Epidemic: Does Age Matter?[NCT05521854] | 600 participants (Anticipated) | Interventional | 2023-05-01 | Recruiting | |||
| [NCT00292123] | Phase 1 | 200 participants (Actual) | Interventional | 1999-06-30 | Completed | ||
| Treatment of Adult ADHD in Methadone Patients[NCT00061087] | Phase 2/Phase 3 | 115 participants (Actual) | Interventional | 1998-02-28 | Completed | ||
| Expanding Capacity in Alberta to Deliver Contingency Patient Management in Outpatient Addiction Treatment: A Randomized Clinical Trial for Methamphetamine Use[NCT04544124] | 544 participants (Anticipated) | Interventional | 2021-01-25 | Active, not recruiting | |||
| Automated Prize-Based Contigency Management to Increase Counseling Attendance in Opiate-Replacement-Therapy Patients[NCT01229163] | Early Phase 1 | 25 participants (Actual) | Interventional | 2010-10-03 | Completed | ||
| The Therapeutic Workplace Initiation Study[NCT00249470] | 117 participants (Actual) | Interventional | 2003-04-30 | Completed | |||
| Way to Quit - Comparative Efficacy, Acceptance and Effectiveness of Health Incentive Structures[NCT01526265] | 2,185 participants (Anticipated) | Interventional | 2012-02-29 | Completed | |||
| A Randomized Community Intervention Trial on Reducing HIV Infection Among Drug Users Attending Methadone Maintenance Treatment(MMT) and Preventing Secondary Transmission From HIV Positive Clients to Their Sexual Partners in China[NCT01108614] | Phase 3 | 12,000 participants (Anticipated) | Interventional | 2009-06-30 | Recruiting | ||
| Evaluating the Impact of Trauma, Trauma-Focused Therapy Services, and COVID-19 Among Patients in the University of Kentucky SMART Clinic[NCT04760418] | 21 participants (Actual) | Interventional | 2021-05-26 | Completed | |||
| [NCT00344812] | Phase 2 | 220 participants | Interventional | 1996-01-31 | Completed | ||
| A Randomized Pilot Study of Long Acting Buprenorphine Injection Compared to Sublingual Buprenorphine/Naloxone Films[NCT03744663] | Phase 2 | 0 participants (Actual) | Interventional | 2022-06-30 | Withdrawn (stopped due to Funding for uninsured subjects could not be realized and staffing after COVID hit was also a problem.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(# opiate- and cocaine-negative urine samples/divided by possible #) x 100 (NCT02487745)
Timeframe: 1 year
| Intervention | percentage of urine samples (Mean) |
|---|---|
| IPS Only | 44.9 |
| IPS Plus Wage Supplement | 64.6 |
(# participants employed /divided by total # of participants) x 100 (NCT02487745)
Timeframe: 1 year
| Intervention | percentage of participants (Number) |
|---|---|
| IPS Only | 27.7 |
| IPS Plus Wage Supplement | 59.1 |
Cost in US Dollars of substance abuse services on the modified Substance Abuse Services Cost Analysis Program (NCT02334215)
Timeframe: 12 months post-release from incarceration
| Intervention | US Dollars (Mean) |
|---|---|
| Methadone Plus Patient Navigation | 3052 |
| Methadone | 2377 |
| Enhanced Treatment as Usual | 1884 |
Mean number of days hospitalized during the 12 months post-release from incarceration (NCT02334215)
Timeframe: 12 months post-release from incarceration
| Intervention | Days (Mean) |
|---|---|
| Methadone Plus Patient Navigation | 2.0 |
| Methadone | 3.4 |
| Enhanced Treatment as Usual | 1.2 |
Official data on participant arrests subsequent to release from index incarceration. (NCT02334215)
Timeframe: one year post-release from incarceration
| Intervention | Participants (Count of Participants) |
|---|---|
| Methadone Plus Patient Navigation | 32 |
| Methadone | 39 |
| Enhanced Treatment as Usual | 36 |
Predicted probability derived from the general linear mixed model of self-reported entry into treatment for opioid use disorder following release from incarceration and being in treatment 30 days post-release (0= no entry in treatment; 1= entry in treatment). (NCT02334215)
Timeframe: 30 days post-release from incarceration
| Intervention | Probability (Least Squares Mean) |
|---|---|
| Methadone Plus Patient Navigation | 0.65 |
| Methadone | 0.62 |
| Enhanced Treatment as Usual | 0.225 |
Drug Risk Scale Score on the Risk Assessment Battery. The scale's range goes from 0 to 22. Higher score represents greater frequency of drug risk behaviors (NCT02334215)
Timeframe: Baseline and 6, and 12 months post-release from incarceration
| Intervention | score on a scale (Least Squares Mean) | ||
|---|---|---|---|
| Baseline | 6 month post-release from incarceration | 12 month post-release | |
| Enhanced Treatment as Usual | 3.11 | 2.16 | 1.03 |
| Methadone | 2.43 | 1.81 | 1.35 |
| Methadone Plus Patient Navigation | 2.30 | 1.52 | .50 |
Environmental domain score on the World Health Organization Quality of Life Scale (WHOQOL-BREF) goes from 1 to 100. A higher score represents a better quality of life. (NCT02334215)
Timeframe: 1, 3, 6, and 12 months post-release from incarceration
| Intervention | score on a scale (Least Squares Mean) | ||||
|---|---|---|---|---|---|
| Baseline | 1 months post-release from incarceration | 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | 54.9 | 65.1 | 63.7 | 57.2 | 59.3 |
| Methadone | 54.6 | 63.6 | 55.1 | 60.6 | 59.4 |
| Methadone Plus Patient Navigation | 48.0 | 56.1 | 51.9 | 59.0 | 54.8 |
Mean number of days reported by participants of their criminal activity during the 30 days preceding the Addiction Severity Index interviews (NCT02334215)
Timeframe: 1, 3, 6, and 12 months post-release from incarceration
| Intervention | Days (Least Squares Mean) | |||
|---|---|---|---|---|
| 1 month post-release from incarceration | 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | 8.22 | 10.59 | 11.49 | 10.18 |
| Methadone | 8.18 | 9.35 | 9.74 | 9.97 |
| Methadone Plus Patient Navigation | 5.22 | 9.79 | 9.24 | 6.88 |
Mean number of participant self-reported days of heroin use in the 30 days preceding the interview on the Addiction Severity Index (ASI) (NCT02334215)
Timeframe: 1, 3, 6, and 12 months post-release from incarceration
| Intervention | Days (Least Squares Mean) | |||
|---|---|---|---|---|
| 1 month post-release from incarceration | 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | 14.88 | 16.18 | 15.42 | 15.35 |
| Methadone | 12.07 | 15.15 | 14.02 | 14.70 |
| Methadone Plus Patient Navigation | 8.66 | 13.46 | 13.56 | 12.35 |
Self report quality of life as reported by participants following release from their index incarceration on a scale from 1 to 5. A higher score is a better outcome. (NCT02334215)
Timeframe: 1, 3, 6, and 12 month post-release from incarceration
| Intervention | units on a scale (Least Squares Mean) | ||||
|---|---|---|---|---|---|
| Baseline | 1 month post-release from incarceration | 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | 3.1 | 3.40 | 3.57 | 3.53 | 3.45 |
| Methadone | 2.8 | 3.56 | 3.46 | 3.58 | 3.43 |
| Methadone Plus Patient Navigation | 2.7 | 3.49 | 3.15 | 3.51 | 3.29 |
Participant self-reported mean number of days of cocaine use in the 30 days preceding the interview on the Addiction Severity Index (ASI) (NCT02334215)
Timeframe: 1, 3, 6, and 12 months post-release from incarceration
| Intervention | Days (Least Squares Mean) | |||
|---|---|---|---|---|
| 1 month post-release from incarceration | 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | 11.01 | 11.94 | 11.94 | 12.63 |
| Methadone | 9.05 | 11.32 | 13.57 | 14.46 |
| Methadone Plus Patient Navigation | 5.95 | 8.83 | 10.74 | 9.60 |
The score on the Physical Domain Scale of the World Health Organization Quality of Life Scale-BREF (WHOQOL-BREF). The scales range is from 0 to 100. The higher score represents better quality of life. (NCT02334215)
Timeframe: 1, 3, 6, and 12 months post-incarceration
| Intervention | score on a scale (Least Squares Mean) | ||||
|---|---|---|---|---|---|
| Baseline | 1 months post-release from incarceration | 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | 57.1 | 68.7 | 67.3 | 61.2 | 60.3 |
| Methadone | 58.3 | 62.2 | 60.1 | 66.3 | 63.8 |
| Methadone Plus Patient Navigation | 54.6 | 62.8 | 60.3 | 68.6 | 63.1 |
Predicted probability derived from the Generalized Linear Mixed Model of meeting the Data and Statistical Manual - 5 criteria for Opioid Use Disorder in response to modified CIDI interview (0= does not meet criteria; 1= meets criteria). (NCT02334215)
Timeframe: one month period prior to the 3, 6, and 12 month post-release from incarceration
| Intervention | Probability (Least Squares Mean) | ||
|---|---|---|---|
| 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | 0.76 | 0.77 | 0.59 |
| Methadone | 0.70 | 0.59 | 0.77 |
| Methadone Plus Patient Navigation | 0.66 | 0.51 | 0.54 |
Predicted Probability derived from the Generalized Linear Mixed of self-reported enrolled in treatment for Opioid Use Disorder at the time of the follow-up interview (0=not enrolled; 1=enrolled). (NCT02334215)
Timeframe: 12 months post-release from incarceration
| Intervention | Probability (Least Squares Mean) | |||
|---|---|---|---|---|
| 1 month post-release from incarceration | 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | .26 | .19 | .24 | .29 |
| Methadone | .56 | .47 | .52 | .27 |
| Methadone Plus Patient Navigation | .63 | .57 | .52 | .40 |
Predicted Probability Derived from the Generalized Linear Mixed Model meeting Data and Statistical Manual - 5 criteria for Cocaine Use Disorder on the modified Composite International Diagnostic Interview (CIDI) (0=Does not meet criteria; 1=meets criteria). (NCT02334215)
Timeframe: 3, 6, and 12 months post-release from incarceration
| Intervention | Probability (Least Squares Mean) | ||
|---|---|---|---|
| 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | .32 | .36 | .30 |
| Methadone | .32 | .35 | .40 |
| Methadone Plus Patient Navigation | .20 | .22 | .32 |
Predicted probability derived from the generalized linear mixed model opioid positive urine tests (0= negative; 1- positive) for heroin, oxycodone, methadone, or buprenorphine -- excluding the latter two positives when they results from prescribed medications to treat opioid use disorder) (NCT02334215)
Timeframe: 1, 3, 6, and 12 months post-release from incarceration
| Intervention | Probability (Least Squares Mean) | |||
|---|---|---|---|---|
| 1 month post-release from incarceration | 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | 0.66 | 0.73 | 0.71 | 0.59 |
| Methadone | 0.72 | 0.72 | 0.63 | 0.71 |
| Methadone Plus Patient Navigation | 0.70 | 0.59 | 0.49 | 0.46 |
Scale score on the Psychological Domain on the World Health Organization Quality of Life Scale (WHOQOL-BREF) goes from 1 to 100. The higher score represents a better quality of life. (NCT02334215)
Timeframe: 1, 3, 6, and 12 months post-release from incarceration
| Intervention | score on a scale (Least Squares Mean) | ||||
|---|---|---|---|---|---|
| Baseline | 1 month post-release from incarceration | 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | 55.9 | 66.7 | 66.6 | 64.8 | 64.4 |
| Methadone | 56.9 | 64.0 | 61.2 | 63.9 | 61.8 |
| Methadone Plus Patient Navigation | 56.8 | 65.5 | 62.6 | 64.9 | 62.0 |
Sex Risk Score on the Risk Assessment Battery (RAB). Higher scores represents greater risk. The score ranges from 0 to 18. (NCT02334215)
Timeframe: Baseline and 6, and 12 months post-release from incarceration
| Intervention | score on a scale (Least Squares Mean) | ||
|---|---|---|---|
| Baseline | 6 months post-release | 12 month post-release | |
| Enhanced Treatment as Usual | 4.68 | 4.27 | 4.17 |
| Methadone | 4.78 | 3.94 | 4.61 |
| Methadone Plus Patient Navigation | 4.52 | 3.93 | 3.78 |
Social domain scale score on the World Health Organization Quality of Life Scale (WHOQOL-BREF) goes from 1 to 100. The higher score represents a better quality of life. (NCT02334215)
Timeframe: 1, 3, 6, and 12 month post-release from incarceration
| Intervention | score on a scale (Least Squares Mean) | ||||
|---|---|---|---|---|---|
| Baseline | 1 month post-release from incarceration | 3 months post-release from incarceration | 6 months post-release from incarceration | 12 months post-release from incarceration | |
| Enhanced Treatment as Usual | 51.3 | 64.9 | 66.4 | 58.8 | 59.1 |
| Methadone | 57.7 | 57.5 | 62.4 | 63.3 | 55.4 |
| Methadone Plus Patient Navigation | 56.9 | 63.6 | 60.9 | 63.3 | 56.6 |
Treatment retention for full 12 weeks of study. (NCT00149630)
Timeframe: 12 weeks
| Intervention | % of subjects who complete 12 wks study (Number) |
|---|---|
| Disulfiram | 77 |
| Placebo | 87 |
(NCT00149630)
Timeframe: Thrice weekly, baseline through week 14.
| Intervention | % cocaine + urines over 2 week blocks (Mean) |
|---|---|
| Placebo CC | 84 |
| Placebo CT/TT | 68 |
| Disulfiram CC | 56 |
| Disulfiram CT/TT | 67 |
Was each participant's urine sample negative for cocaine at each of the Monday, Wednesday, Friday urine samples scheduled throughout the intervention evaluation period? (NCT01416584)
Timeframe: 6 months
| Intervention | percentage of urine samples (Mean) |
|---|---|
| Usual Care Control | 25 |
| Methadone Contingency Group | 44 |
| Methadone & Abstinence Contingency | 48 |
Was each participant's urine sample negative for opiates at each of the Monday, Wednesday, Friday urine samples scheduled throughout the intervention evaluation period? (NCT01416584)
Timeframe: 6 months
| Intervention | percentage of M,W,F urine samples (Mean) |
|---|---|
| Usual Care Control | 43 |
| Methadone Contingency Group | 50 |
| Methadone & Abstinence Contingency | 65 |
Percentage of urine sample negative for opiates at each of the six 30-day assessments scheduled throughout the intervention evaluation (NCT01416584)
Timeframe: 6 months
| Intervention | percentage of opiate negative (Mean) |
|---|---|
| Usual Care Control | 54 |
| Methadone Contingency Group | 61 |
| Methadone & Abstinence Contingency | 75 |
Was the participant's urine sample negative for cocaine at each of the six 30-day assessments scheduled throughout the intervention evaluation period? (NCT01416584)
Timeframe: 6 months
| Intervention | percentage of cocaine negative (Mean) |
|---|---|
| Usual Care Control | 32 |
| Methadone Contingency Group | 55 |
| Methadone & Abstinence Contingency | 57 |
The percentage of months in which participants were enrolled in methadone treatment during the 6-month intervention evaluation period? (NCT01416584)
Timeframe: 6 months
| Intervention | percent of months in methadone treatment (Mean) |
|---|---|
| Usual Care Control | 81 |
| Methadone Contingency Group | 82 |
| Methadone & Abstinence Contingency | 88 |
Percentage of cocaine positive urine samples as measured by Preston new use rule (50% reduction in cocaine metabolites from previous urine) (NCT00685178)
Timeframe: Urine samples collected 3 times weekly from week 1 through 26
| Intervention | percentage of positive urine samples (Number) |
|---|---|
| 1 Topiramate + CR | 45.4 |
| 2 Topiramate + NonCR | 42.7 |
| 3 Placebo + CR | 53.5 |
| 4 Placebo + NonCR | 46.5 |
"Voucher earnings used as a measurement of contigency management (CM) or operate conditioning. Volunteers were rewarded vouchers of escalating monetary value for cocaine abstinence, as indicated by a cocaine negative urine sample. The first cocaine negative urine earned a $2.50 voucher, and the value increased by $1.50 for each subsequent cocaine negative sample. Volunteers were awarded a bonus of $10.00 for every three consecutive cocaine negative urine samples. Urine samples were collected 3 times per week, and vouchers were attainable between Weeks 8 and 20.~Contingency management as a measurement of operant conditioning in which positive reinforcement is applied (in this case vouchers of monetary value) and cocaine abstinence" (NCT00685178)
Timeframe: 12 weeks (Weeks 8-20)
| Intervention | Dollars (Mean) |
|---|---|
| 1 Topiramate + CR | 421.25 |
| 2 Topiramate + NonCR | 343.26 |
| 3 Placebo + CR | 394.69 |
| 4 Placebo + NonCR | 203.51 |
Acceptability, defined as satisfaction with or tolerability of the proposed approach, was measured quantitatively by session attendance. Specifically, we measured the % of patients who attended ≥75% of core intervention sessions. (NCT04248933)
Timeframe: Assessed between the baseline assessment and the acute outcome (approximately 12-weeks post-baseline assessment/ post-treatment assessment)
| Intervention | Participants (Count of Participants) |
|---|---|
| "Peer-Delivered Behavioral Activation (Peer Activate)" | 26 |
Feasibility, defined as the suitability and practicability of the approach, was measured quantitatively as the % of patients who agreed to participate in the intervention. (NCT04248933)
Timeframe: Assessed between the baseline assessment and the acute outcome (approximately 12-weeks post-baseline assessment/ post-treatment assessment)
| Intervention | Participants (Count of Participants) |
|---|---|
| "Peer-Delivered Behavioral Activation (Peer Activate)" | 32 |
Fidelity, defined as the delivery of the intervention as intended, was measured based on PRS adherence to the intervention delivery. A random selection of 20% of sessions was rated for fidelity, and we assessed the % of intervention components delivered as intended. (NCT04248933)
Timeframe: Assessed between the baseline assessment and the acute outcome (approximately 12-weeks post-baseline assessment/ post-treatment assessment)
| Intervention | Percentage fidelity to treatment (Mean) |
|---|---|
| "Peer-Delivered Behavioral Activation (Peer Activate)" | 87.9 |
Percent of patients retained in MOUD treatment at three months (i.e. still engaged in care) after intervention enrollment. (NCT04248933)
Timeframe: Measured daily from intake to post-treatment (approximately 12-weeks)
| Intervention | Participants (Count of Participants) |
|---|---|
| "Peer-Delivered Behavioral Activation (Peer Activate)" | 31 |
cocaine urine test results-percent of participants testing positive for cocaine (NCT00378079)
Timeframe: one year post prison release
| Intervention | percent cocaine positive participants (Number) |
|---|---|
| 1 Counseling Only in Prison | 71.9 |
| 2 Counseling Only in Prison, With Initiation of Methadone Main | 66.6 |
| 3 Counseling and Methadone Maintenance in Prison, With Continu | 43.2 |
self reported days of criminal activity (NCT00378079)
Timeframe: one year post prison release
| Intervention | number of days (Mean) |
|---|---|
| 1 Counseling Only in Prison | 106.7 |
| 2 Counseling Only in Prison, With Initiation of Methadone Main | 65.2 |
| 3 Counseling and Methadone Maintenance in Prison, With Continu | 81.8 |
number of days employed, past 30 days-self report, assessed one year post-prison release (NCT00378079)
Timeframe: one year
| Intervention | number of days employed, past 30 (Mean) |
|---|---|
| 1 Counseling Only in Prison | 12.0 |
| 2 Counseling Only in Prison, With Initiation of Methadone Main | 10.3 |
| 3 Counseling and Methadone Maintenance in Prison, With Continu | 8.5 |
opioid urine test results-percent of participants who were opioid-positive (NCT00378079)
Timeframe: results at one year post prison release
| Intervention | % participants opioid positive (Number) |
|---|---|
| 1 Counseling Only in Prison | 65.6 |
| 2 Counseling Only in Prison, With Initiation of Methadone Main | 48.7 |
| 3 Counseling and Methadone Maintenance in Prison, With Continu | 25.0 |
days in community treatment (NCT00378079)
Timeframe: one year post prison release
| Intervention | Days in community treatment (Mean) |
|---|---|
| 1 Counseling Only in Prison | 23.1 |
| 2 Counseling Only in Prison, With Initiation of Methadone Main | 91.3 |
| 3 Counseling and Methadone Maintenance in Prison, With Continu | 166.0 |
Peak antibody levels after five vaccinations with TA-CD, which occurred at week 16. (NCT00969878)
Timeframe: During the 18 weeks study period.
| Intervention | micrograms/ml (Mean) |
|---|---|
| Placebo Injection | 0 |
| TA-CD Vaccination | 59 |
Number of patients having at least 2 weeks of cocaine-free urines between weeks 9-16 after vaccination with five doses of TA-CD 400 µg compared to placebo (NCT00969878)
Timeframe: Over 8 weeks ( Study Weeks 9 to 16 inclusive)
| Intervention | participants (Number) |
|---|---|
| Placebo Injection | 21 |
| TA-CD Vaccination | 30 |
Percentage of people reporting that they traded sex for drugs or money (NCT00249496)
Timeframe: 1 year
| Intervention | percentage of participants (Mean) |
|---|---|
| Employment Only | 16.7 |
| Contingency Management | 0 |
(The number of monthly urine samples negative for opiates/total number of urine samples) x 100 (NCT00249496)
Timeframe: 1 year
| Intervention | percentage of opiate negative (Mean) |
|---|---|
| Employment Only | 90.6 |
| Contingency Management | 88.6 |
The percentage of urine samples collected at monthly assessments that are negative for cocaine. (NCT00249496)
Timeframe: 1 year
| Intervention | percentage of urine samples (Mean) |
|---|---|
| Employment Only | 51.8 |
| Contingency Management | 79.3 |
Self-reports of substance use will be documented at each contact via the Substance Use Calendar. Similar to the Form-90 and the Time Line Follow-Back, which have been shown to be reliable and valid instruments for monitoring substance use and other outcomes in longitudinal studies202-204, the Substance Use Calendar allows a flexible, continuous evaluation of substance use on a daily basis. (NCT00350870)
Timeframe: 12 weeks
| Intervention | percentage of days abstinent (Mean) |
|---|---|
| Placebo | 72.2 |
| Disulfiram | 79.2 |
| Placebo Plus Contingency Management | 91.1 |
| Disulfiram Plus Contingency Management | 69.6 |
We will use the Roche onsite TESTCUP system for detection of cocaine, methamphetamine, THC, benzodiazepenes, and opioids. (NCT00350870)
Timeframe: 12 weeks
| Intervention | percentage of negative urines (Mean) |
|---|---|
| Placebo | 17.9 |
| Disulfiram | 30.1 |
| Placebo Plus Contingency Management | 53 |
| Disulfiram Plus Contingency Management | 42.6 |
The primary endpoint is the longest period of continuous abstinence from illicit opioids, where abstinence is measured using lab-verified in-person urine-tests, saliva tests, or subject reporting (in the absence of urine testing). (NCT04235582)
Timeframe: Time = 4 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Outcomes Group | 6 |
| Inputs Group | 5 |
| Combination Group | 5 |
The primary endpoint is the longest period of continuous abstinence from illicit opioids, where abstinence is measured using lab-verified in-person urine-tests, saliva tests, or subject reporting (in the absence of urine testing). (NCT04235582)
Timeframe: Time = 8 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Outcomes Group | 6 |
| Inputs Group | 5 |
| Combination Group | 3 |
The primary endpoint is the % of opioid-negative saliva or urine tests in each group at Week 12 (NCT04235582)
Timeframe: Time = 12 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Outcomes Group | 6 |
| Inputs Group | 5 |
| Combination Group | 3 |
Percentage of Monday, Wednesday, Friday urine samples that are negative for cocaine (NCT00249470)
Timeframe: 6 months
| Intervention | percentage of cocaine negative (Mean) |
|---|---|
| Abstinence & Work | 29 |
| Work Only | 10 |
Report no injection drug use or crack cocaine use. (NCT00249470)
Timeframe: every month for 6 months
| Intervention | percentage of participants (Mean) |
|---|---|
| Abstinence & Work | 28.0 |
| Work Only | 16.1 |
(total number of opiate-negative urine samples divided by the total number of urine samples provided)*100 (NCT00249470)
Timeframe: every month for 6 months
| Intervention | percentage of opiate negative (Mean) |
|---|---|
| Abstinence & Work | 55.4 |
| Work Only | 62.5 |
20 reviews available for methadone and Cocaine Abuse
| Article | Year |
|---|---|
A systematic review and meta-analysis of medications for stimulant use disorders in patients with co-occurring opioid use disorders.
Topics: Analgesics, Opioid; Antidepressive Agents; Central Nervous System Stimulants; Cocaine; Cocaine-Relat | 2020 |
Progress in agonist therapy for substance use disorders: Lessons learned from methadone and buprenorphine.
Topics: Analgesics, Opioid; Buprenorphine; Central Nervous System Stimulants; Cocaine-Related Disorders; Dex | 2019 |
Mixed κ/μ partial opioid agonists as potential treatments for cocaine dependence.
Topics: Analgesics, Opioid; Animals; Buprenorphine; Cocaine-Related Disorders; Dose-Response Relationship, D | 2014 |
The Role of Behavioral Interventions in Buprenorphine Maintenance Treatment: A Review.
Topics: Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Combined Modality Therapy; Heroin Depend | 2017 |
Efficacy of opiate maintenance therapy and adjunctive interventions for opioid dependence with comorbid cocaine use disorders: A systematic review and meta-analysis of controlled clinical trials.
Topics: Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Humans; Methadone; Narcotics; Opioid-Rel | 2009 |
Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member | 2010 |
Prenatal drug exposure: infant and toddler outcomes.
Topics: Buprenorphine; Child Development; Child, Preschool; Cocaine; Cocaine-Related Disorders; Female; Hero | 2010 |
Pharmacotherapies for adolescent substance use disorders.
Topics: Adolescent; Alcohol Deterrents; Alcoholism; Cocaine-Related Disorders; Disulfiram; Humans; Marijuana | 2010 |
Drug-related decrease in neuropsychological functions of abstinent drug users.
Topics: Alcoholism; Amphetamine-Related Disorders; Cannabis; Central Nervous System Stimulants; Cocaine; Coc | 2011 |
The effectiveness of opioid maintenance treatment in prison settings: a systematic review.
Topics: Buprenorphine; Cocaine-Related Disorders; Continuity of Patient Care; Crime; Epidemiologic Methods; | 2012 |
Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics.
Topics: Animals; Basal Ganglia; Cocaine-Related Disorders; Dopamine; Dopaminergic Neurons; Gene Expression R | 2012 |
Pharmacologic treatments for heroin and cocaine dependence.
Topics: Buprenorphine; Clonidine; Cocaine-Related Disorders; Comorbidity; Heroin Dependence; Humans; Mental | 2003 |
Sex differences in cocaine-dependent individuals' response to disulfiram treatment.
Topics: Adult; Cocaine-Related Disorders; Disulfiram; Drug Therapy, Combination; Enzyme Inhibitors; Female; | 2004 |
[Evaluation of methadone dispensing in Belgium--study synopsis].
Topics: Adult; Analgesics, Opioid; Belgium; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Ma | 2004 |
Pharmacotherapy for pregnant women with addictions.
Topics: Adolescent; Adult; Behavior, Addictive; Cocaine-Related Disorders; Female; Follow-Up Studies; Gestat | 2004 |
Methadone-induced Torsade de pointes tachycardias.
Topics: Adult; Analgesics, Opioid; Cocaine-Related Disorders; Electrocardiography; Female; Humans; Long QT S | 2005 |
Toward a unitary perspective on the bipolar spectrum and substance abuse: opiate addiction as a paradigm.
Topics: Alcoholism; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cocaine-Related Disorders; Comorbid | 2006 |
Multimodal drug addiction treatment: a field comparison of methadone and buprenorphine among heroin- and cocaine-dependent patients.
Topics: Adult; Buprenorphine; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Male; Methadone; | 2006 |
Early development of infants exposed to drugs prenatally.
Topics: Alcoholism; Child Abuse; Child Development; Child, Preschool; Cocaine; Cocaine-Related Disorders; Et | 1999 |
Pharmacologic treatments for drug and alcohol dependence.
Topics: Alcohol Deterrents; Alcoholism; Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Cocaine- | 1999 |
118 trials available for methadone and Cocaine Abuse
| Article | Year |
|---|---|
Bupropion Slow Release vs Placebo With Adaptive Incentives for Cocaine Use Disorder in Persons Receiving Methadone for Opioid Use Disorder: A Randomized Clinical Trial.
Topics: Bupropion; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Humans; Male; Methadone; | 2023 |
Abstinence-contingent wage supplements to promote drug abstinence and employment: a randomised controlled trial.
Topics: Adult; Analgesics, Opioid; Baltimore; Cocaine-Related Disorders; Employment; Female; Humans; Male; M | 2020 |
Evaluating a longitudinal mediation model of perceived stress, depressive symptoms, and substance use treatment outcomes.
Topics: Adult; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Depression; Female; Galantamine; Hum | 2020 |
Randomized trial of methadone treatment of arrestees: 24-month post-release outcomes.
Topics: Adult; Analgesics, Opioid; Baltimore; Cocaine-Related Disorders; Costs and Cost Analysis; Crime; Dru | 2021 |
The OPRD1 rs678849 variant influences outcome of disulfiram treatment for cocaine dependency in methadone-maintained patients.
Topics: Adult; Alleles; Cocaine; Cocaine-Related Disorders; Disulfiram; Female; Genotype; Humans; Male; Meth | 2021 |
Alcohol use disorders are associated with increased HIV risk behaviors in cocaine-dependent methadone patients.
Topics: Adult; Alcoholism; Behavior Therapy; Cocaine-Related Disorders; Comorbidity; Female; HIV Infections; | 2017 |
fMRI Stroop and behavioral treatment for cocaine-dependence: Preliminary findings in methadone-maintained individuals.
Topics: Adult; Analgesics, Opioid; Brain; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined | 2019 |
Double-Blind Placebo-Controlled Trial of Galantamine for Methadone-Maintained Individuals With Cocaine Use Disorder: Secondary Analysis of Effects on Illicit Opioid Use.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Cholinesterase Inhibitors; Cocaine-Related Disorders; D | 2019 |
ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse.
Topics: Adult; Alleles; Cocaine-Related Disorders; Disulfiram; Female; Genotype; Humans; Male; Methadone; Po | 2013 |
Pharmacogenetic randomized trial for cocaine abuse: disulfiram and α1A-adrenoceptor gene variation.
Topics: Adult; Alcohol Deterrents; Alleles; Cocaine-Related Disorders; Disulfiram; Dopamine beta-Hydroxylase | 2013 |
Computer-assisted delivery of cognitive-behavioral therapy: efficacy and durability of CBT4CBT among cocaine-dependent individuals maintained on methadone.
Topics: Adult; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; H | 2014 |
The therapeutic workplace to promote treatment engagement and drug abstinence in out-of-treatment injection drug users: a randomized controlled trial.
Topics: Analgesics, Opioid; Baltimore; Cocaine-Related Disorders; Employment; Health Behavior; Hospitals, Te | 2014 |
Topiramate for cocaine dependence during methadone maintenance treatment: a randomized controlled trial.
Topics: Adolescent; Adult; Cocaine-Related Disorders; Double-Blind Method; Female; Fructose; Humans; Male; M | 2014 |
Standard magnitude prize reinforcers can be as efficacious as larger magnitude reinforcers in cocaine-dependent methadone patients.
Topics: Adult; Behavior Therapy; Cocaine-Related Disorders; Female; Humans; Male; Methadone; Middle Aged; Na | 2015 |
Drug use, health and social outcomes of hard-to-treat heroin addicts receiving supervised injectable opiate treatment: secondary outcomes from the Randomized Injectable Opioid Treatment Trial (RIOTT).
Topics: Administration, Oral; Adult; Alcohol Drinking; Analgesics, Opioid; Cocaine-Related Disorders; Comorb | 2015 |
Employment-based abstinence reinforcement promotes opiate and cocaine abstinence in out-of-treatment injection drug users.
Topics: Adult; Behavior Therapy; Cocaine-Related Disorders; Combined Modality Therapy; Drug Users; Employmen | 2014 |
Topiramate impairs cognitive function in methadone-maintained individuals with concurrent cocaine dependence.
Topics: Adult; Cocaine-Related Disorders; Cognition Disorders; Diagnosis, Dual (Psychiatry); Double-Blind Me | 2015 |
Self-reported cravings for heroin and cocaine during maintenance treatment with slow-release oral morphine compared with methadone: a randomized, crossover clinical trial.
Topics: Adult; Cocaine-Related Disorders; Cross-Over Studies; Female; Heroin Dependence; Humans; Male; Metha | 2015 |
No evidence for reduction of opioid-withdrawal symptoms by cannabis smoking during a methadone dose taper.
Topics: Adult; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug Therapy, Combination; Femal | 2015 |
Alexithymia level and response to computer-based training in cognitive behavioral therapy among cocaine-dependent methadone maintained individuals.
Topics: Adult; Affective Symptoms; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modalit | 2015 |
Can persons with a history of multiple addiction treatment episodes benefit from technology delivered behavior therapy? A moderating role of treatment history at baseline.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Biomedical Technology; Cocaine-Related Disorders; Couns | 2016 |
Correlates of cocaine use during methadone treatment: implications for screening and clinical management (ANRS Methaville study).
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Cocaine-Related Disorders; C | 2016 |
Correlates of cocaine use during methadone treatment: implications for screening and clinical management (ANRS Methaville study).
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Cocaine-Related Disorders; C | 2016 |
Correlates of cocaine use during methadone treatment: implications for screening and clinical management (ANRS Methaville study).
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Cocaine-Related Disorders; C | 2016 |
Correlates of cocaine use during methadone treatment: implications for screening and clinical management (ANRS Methaville study).
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Cocaine-Related Disorders; C | 2016 |
Efficacy of cocaine contingency management in heroin-assisted treatment: Results of a randomized controlled trial.
Topics: Adult; Analgesics, Opioid; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Ther | 2016 |
Anticipatory reward processing among cocaine-dependent individuals with and without concurrent methadone-maintenance treatment: Relationship to treatment response.
Topics: Adult; Analgesics, Opioid; Anticipation, Psychological; Behavior Therapy; Cocaine-Related Disorders; | 2016 |
Emotion regulation strategies in individuals with cocaine use disorder maintained on methadone.
Topics: Adult; Analgesics, Opioid; Cocaine-Related Disorders; Cognition; Cognitive Behavioral Therapy; Combi | 2016 |
Aripiprazole for cocaine abstinence: a randomized-controlled trial with ecological momentary assessment.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Cocaine-Related Disorders; Craving; Double-Blind Method; | 2017 |
Carvedilol does not reduce cocaine use in methadone-maintained cocaine users.
Topics: Adrenergic beta-Antagonists; Adult; Analgesics, Opioid; Carbazoles; Carvedilol; Cocaine-Related Diso | 2017 |
Ethnic differences in HIV risk behaviors among methadone-maintained women receiving contingency management for cocaine use disorders.
Topics: Adult; Behavior Therapy; Black People; Cocaine-Related Disorders; Female; Follow-Up Studies; Hispani | 2008 |
Effect of religiosity and spirituality on drug treatment outcomes.
Topics: Adult; Analgesics, Opioid; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Male; Metha | 2009 |
Abstinence-contingent reinforcement and engagement in non-drug-related activities among illicit drug abusers.
Topics: Adolescent; Adult; Baltimore; Cocaine-Related Disorders; Female; Humans; Illicit Drugs; Leisure Acti | 2008 |
Promoting abstinence from cocaine and heroin with a methadone dose increase and a novel contingency.
Topics: Adult; Breath Tests; Cocaine-Related Disorders; Counseling; Data Interpretation, Statistical; Dose-R | 2009 |
Attendance rates in a workplace predict subsequent outcome of employment-based reinforcement of cocaine abstinence in methadone patients.
Topics: Absenteeism; Adult; Baltimore; Cocaine-Related Disorders; Female; Follow-Up Studies; Heroin Dependen | 2008 |
Voucher-based contingent reinforcement of smoking abstinence among methadone-maintained patients: a pilot study.
Topics: Adult; Cocaine-Related Disorders; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Male | 2008 |
Using the experience sampling method in the context of contingency management for substance abuse treatment.
Topics: Adult; Affect; Ambulatory Care; Cell Phone; Cocaine-Related Disorders; Conditioning, Operant; Data I | 2008 |
Comparable efficacy of contingency management for cocaine dependence among African American, Hispanic, and White methadone maintenance clients.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Behavior Therapy; Black or African American; Cocain | 2009 |
A randomized clinical trial of methadone maintenance for prisoners: results at 12 months postrelease.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Counseling; Follow-Up Studies; Heroin Dependence; Humans; | 2009 |
Diacetylmorphine versus methadone for the treatment of opioid addiction.
Topics: Administration, Oral; Adult; Cocaine-Related Disorders; Double-Blind Method; Drug Overdose; Female; | 2009 |
Diacetylmorphine versus methadone for the treatment of opioid addiction.
Topics: Administration, Oral; Adult; Cocaine-Related Disorders; Double-Blind Method; Drug Overdose; Female; | 2009 |
Diacetylmorphine versus methadone for the treatment of opioid addiction.
Topics: Administration, Oral; Adult; Cocaine-Related Disorders; Double-Blind Method; Drug Overdose; Female; | 2009 |
Diacetylmorphine versus methadone for the treatment of opioid addiction.
Topics: Administration, Oral; Adult; Cocaine-Related Disorders; Double-Blind Method; Drug Overdose; Female; | 2009 |
Predicting cocaine group treatment outcome in cocaine-abusing methadone patients.
Topics: Adult; Aged; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Dose-Response Relatio | 2009 |
Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: a randomized, double-blind, placebo-controlled efficacy trial.
Topics: Adolescent; Adult; Cocaine-Related Disorders; Double-Blind Method; Enzyme-Linked Immunosorbent Assay | 2009 |
Smoking in pregnant women screened for an opioid agonist medication study compared to related pregnant and non-pregnant patient samples.
Topics: Adult; Cocaine-Related Disorders; Female; Health Behavior; Humans; Methadone; Narcotics; Opioid-Rela | 2009 |
Contingency management for cocaine use in methadone maintenance patients: when does abstinence happen?
Topics: Adult; Analysis of Variance; Behavior Therapy; Chi-Square Distribution; Cocaine-Related Disorders; F | 2010 |
Randomized, double blind, placebo-controlled trial of disulfiram for the treatment of cocaine dependence in methadone-stabilized patients.
Topics: Adult; Alcohol Drinking; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Disulfira | 2011 |
Employment-based abstinence reinforcement as a maintenance intervention for the treatment of cocaine dependence: post-intervention outcomes.
Topics: Adult; Baltimore; Behavior Therapy; Breath Tests; Cocaine-Related Disorders; Employment; Female; Hum | 2011 |
A randomized controlled trial of fluoxetine in the treatment of cocaine dependence among methadone-maintained patients.
Topics: Adult; Cocaine-Related Disorders; Double-Blind Method; Female; Fluoxetine; Humans; Male; Methadone; | 2011 |
Interim methadone treatment compared to standard methadone treatment: 4-month findings.
Topics: Adult; Cocaine-Related Disorders; Counseling; Crime; Female; Heroin Dependence; Humans; Male; Methad | 2011 |
Concurrent alcohol dependence among methadone-maintained cocaine abusers is associated with greater abstinence.
Topics: Adult; Alcohol-Related Disorders; Cocaine-Related Disorders; Female; Follow-Up Studies; Humans; Male | 2011 |
Amount of earnings during prize contingency management treatment is associated with posttreatment abstinence outcomes.
Topics: Adult; Awards and Prizes; Cocaine-Related Disorders; Female; Humans; Logistic Models; Male; Methadon | 2011 |
Randomized trial of standard methadone treatment compared to initiating methadone without counseling: 12-month findings.
Topics: Adult; Ambulatory Care; Cocaine-Related Disorders; Counseling; Female; Heroin Dependence; Humans; Ma | 2012 |
Non-attendance at counselling therapy in cocaine-using methadone-maintained patients: lessons learnt from an abandoned randomised controlled trial.
Topics: Adult; Cocaine-Related Disorders; Counseling; Cross-Sectional Studies; Female; Humans; Male; Methado | 2012 |
Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: a randomized placebo-controlled trial.
Topics: Adult; Alcohol Deterrents; Alcohol Drinking; Cocaine-Related Disorders; Counseling; Demography; Diag | 2012 |
Pharmacogenetic randomized trial for cocaine abuse: disulfiram and dopamine β-hydroxylase.
Topics: Adult; Cocaine-Related Disorders; Disulfiram; Dopamine beta-Hydroxylase; Drug Therapy, Combination; | 2013 |
Modifying the role of serotonergic 5-HTTLPR and TPH2 variants on disulfiram treatment of cocaine addiction: a preliminary study.
Topics: Adult; Alleles; Cocaine; Cocaine-Related Disorders; Comorbidity; Disulfiram; Female; Genetic Carrier | 2012 |
A randomized investigation of methadone doses at or over 100 mg/day, combined with contingency management.
Topics: Adult; Cocaine-Related Disorders; Disease Management; Dose-Response Relationship, Drug; Double-Blind | 2013 |
The Recovery Line: A pilot trial of automated, telephone-based treatment for continued drug use in methadone maintenance.
Topics: Adaptation, Psychological; Adult; Automation; Cocaine-Related Disorders; Feasibility Studies; Female | 2013 |
A comparison of contingency management and cognitive-behavioral approaches during methadone maintenance treatment for cocaine dependence.
Topics: Adult; Behavior Therapy; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Female; H | 2002 |
Treating cocaine-using methadone patients: predictors of outcomes in a psychosocial clinical trial.
Topics: Adult; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; H | 2002 |
Cognitive-behavioral therapy plus contingency management for cocaine use: findings during treatment and across 12-month follow-up.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Baltimore; Behavior Therapy; Cocaine-Related Disord | 2003 |
A preliminary, controlled investigation of magnesium L-aspartate hydrochloride for illicit cocaine and opiate use in methadone-maintained patients.
Topics: Adult; Aspartic Acid; Cocaine-Related Disorders; Drug Administration Schedule; Female; Humans; Illic | 2003 |
Desipramine in opioid-dependent cocaine abusers maintained on buprenorphine vs methadone.
Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Buprenorphine; Cocaine-Related Disorder | 1999 |
Do noncontingent vouchers increase drug use?
Topics: Adult; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Female; Humans; Logistic Models; | 2003 |
Single- versus dual-drug target: effects in a brief abstinence incentive procedure.
Topics: Adolescent; Adult; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Linear Models; Male | 2003 |
Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study.
Topics: Adult; Analysis of Variance; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Drug Administr | 2003 |
Agonist-like or antagonist-like treatment for cocaine dependence with methadone for heroin dependence: two double-blind randomized clinical trials.
Topics: Adolescent; Adult; Blood Pressure; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; | 2004 |
Targeting HIV-related outcomes with intravenous drug users maintained on methadone: a randomized clinical trial of a harm reduction group therapy.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Cocaine-Related Disorders; Condoms; Costs and Cost Anal | 2004 |
Targeting HIV-related outcomes with intravenous drug users maintained on methadone: a randomized clinical trial of a harm reduction group therapy.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Cocaine-Related Disorders; Condoms; Costs and Cost Anal | 2004 |
Targeting HIV-related outcomes with intravenous drug users maintained on methadone: a randomized clinical trial of a harm reduction group therapy.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Cocaine-Related Disorders; Condoms; Costs and Cost Anal | 2004 |
Targeting HIV-related outcomes with intravenous drug users maintained on methadone: a randomized clinical trial of a harm reduction group therapy.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Cocaine-Related Disorders; Condoms; Costs and Cost Anal | 2004 |
Cost effectiveness of disulfiram: treating cocaine use in methadone-maintained patients.
Topics: Adult; Analgesics, Opioid; Cocaine-Related Disorders; Connecticut; Cost-Benefit Analysis; Disulfiram | 2004 |
Directly observed therapy for the management of HIV-infected patients in a methadone program.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cocaine-Related Disord | 2004 |
A randomized trial of long-term reinforcement of cocaine abstinence in methadone-maintained patients who inject drugs.
Topics: Adolescent; Adult; Cocaine-Related Disorders; Female; Humans; Injections, Intravenous; Male; Methado | 2004 |
Behavioral contingencies improve counseling attendance in an adaptive treatment model.
Topics: Adult; Alcoholism; Ambulatory Care; Baltimore; Behavior Therapy; Cocaine-Related Disorders; Comorbid | 2004 |
Cocaine abstinence during methadone maintenance: effects of repeated brief exposure to voucher-based reinforcement.
Topics: Adult; Cocaine-Related Disorders; Female; Humans; Male; Methadone; Motivation; Reinforcement, Psycho | 2004 |
Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Combined Moda | 2005 |
Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Combined Moda | 2005 |
Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Combined Moda | 2005 |
Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Combined Moda | 2005 |
Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Combined Moda | 2005 |
Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Combined Moda | 2005 |
Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Combined Moda | 2005 |
Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Combined Moda | 2005 |
Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Combined Moda | 2005 |
Prize reinforcement contingency management for cocaine dependence: integration with group therapy in a methadone clinic.
Topics: Adult; Ambulatory Care; Awards and Prizes; Cocaine-Related Disorders; Combined Modality Therapy; Del | 2005 |
A combined cognitive and behavioral intervention for cocaine-using methadone clients.
Topics: Adult; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Female; Follow-Up Studies; Humans; M | 2005 |
Changes in HIV risk behaviors among patients receiving combined pharmacological and behavioral interventions for heroin and cocaine dependence.
Topics: Adult; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; H | 2006 |
Temperament characteristics, as assessed by the tridimensional personality questionnaire, moderate the response to sertraline in depressed opiate-dependent methadone patients.
Topics: Adult; Cocaine-Related Disorders; Depressive Disorder; Female; Heroin Dependence; Humans; Male; Meth | 2006 |
Prize-based contingency management does not increase gambling.
Topics: Adult; Alcoholism; Ambulatory Care; Amphetamine-Related Disorders; Central Nervous System Stimulants | 2006 |
A randomized controlled trial of interim methadone maintenance.
Topics: Adult; Analgesics, Opioid; Baltimore; Cocaine-Related Disorders; Crime; Drug Administration Schedule | 2006 |
Six-month trial of bupropion with contingency management for cocaine dependence in a methadone-maintained population.
Topics: Adult; Behavior Therapy; Bupropion; Cocaine; Cocaine-Related Disorders; Combined Modality Therapy; C | 2006 |
A placebo controlled, double-blind study of mecamylamine treatment for cocaine dependence in patients enrolled in an opiate replacement program.
Topics: Administration, Cutaneous; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Drug Evaluation, | 2005 |
Nonreporting of cannabis use: Predictors and relationship to treatment outcome in methadone maintained patients.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Behavior Therapy; Black or African American; Cocain | 2007 |
Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients.
Topics: Adult; Amines; Anti-Anxiety Agents; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combine | 2007 |
Pilot cluster-randomised trial of adjunctive motivational interviewing to reduce crack cocaine use in clients on methadone maintenance.
Topics: Adult; Awareness; Cluster Analysis; Cocaine-Related Disorders; Crack Cocaine; Demography; Feasibilit | 2007 |
A randomized clinical trial of methadone maintenance for prisoners: results at 1-month post-release.
Topics: Adult; Age of Onset; Baltimore; Cocaine; Cocaine-Related Disorders; Follow-Up Studies; Heroin Depend | 2007 |
Contingency management in cocaine abusers: a dose-effect comparison of goods-based versus cash-based incentives.
Topics: Behavior Therapy; Cocaine-Related Disorders; Female; Humans; Male; Methadone; Motivation; Narcotics; | 2007 |
Randomized trial of prize-based reinforcement density for simultaneous abstinence from cocaine and heroin.
Topics: Adult; Cocaine-Related Disorders; Comorbidity; Double-Blind Method; Female; Heroin Dependence; Human | 2007 |
Randomized trial of prize-based reinforcement density for simultaneous abstinence from cocaine and heroin.
Topics: Adult; Cocaine-Related Disorders; Comorbidity; Double-Blind Method; Female; Heroin Dependence; Human | 2007 |
Randomized trial of prize-based reinforcement density for simultaneous abstinence from cocaine and heroin.
Topics: Adult; Cocaine-Related Disorders; Comorbidity; Double-Blind Method; Female; Heroin Dependence; Human | 2007 |
Randomized trial of prize-based reinforcement density for simultaneous abstinence from cocaine and heroin.
Topics: Adult; Cocaine-Related Disorders; Comorbidity; Double-Blind Method; Female; Heroin Dependence; Human | 2007 |
Progesterone effects on cocaine use in male cocaine users maintained on methadone: a randomized, double-blind, pilot study.
Topics: Adult; Cocaine-Related Disorders; Double-Blind Method; Humans; Male; Methadone; Narcotics; Pilot Pro | 2007 |
A randomized trial of employment-based reinforcement of cocaine abstinence in injection drug users.
Topics: Cocaine; Cocaine-Related Disorders; Demography; Employment; Female; Humans; Incidence; Male; Methado | 2007 |
Contingency management reduces injection-related HIV risk behaviors in heroin and cocaine using outpatients.
Topics: Adolescent; Adult; Aged; Cocaine-Related Disorders; Counseling; Female; Heroin Dependence; HIV Infec | 2008 |
Randomized trial of contingent prizes versus vouchers in cocaine-using methadone patients.
Topics: Adolescent; Cocaine-Related Disorders; Female; Humans; Incidence; Male; Methadone; Narcotics; Reinfo | 2007 |
Dysregulation of emotional response in current and abstinent heroin users: negative heightening and positive blunting.
Topics: Adult; Alcoholism; Arousal; Cocaine-Related Disorders; Emotions; Female; Heroin Dependence; Humans; | 2008 |
Prognostic factors in Buprenorphine- versus methadone-maintained patients.
Topics: Adult; Alcoholism; Antisocial Personality Disorder; Benzodiazepines; Buprenorphine; Cocaine-Related | 1998 |
Medication take-home doses and contingency management.
Topics: Adult; Cocaine-Related Disorders; Female; Fluoxetine; Humans; Male; Methadone; Middle Aged; Opioid-R | 1998 |
Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts.
Topics: Adult; Antidepressive Agents, Second-Generation; Behavior, Addictive; Cocaine; Cocaine-Related Disor | 1998 |
Broad beneficial effects of cocaine abstinence reinforcement among methadone patients.
Topics: Adult; Analysis of Variance; Behavior Therapy; Cocaine-Related Disorders; Female; Humans; Longitudin | 1998 |
Use of methadone take-home contingencies with persistent opiate and cocaine abusers.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Cocaine-Related Disorders; Female; Heroin Dependenc | 1999 |
Day treatment versus enhanced standard methadone services for opioid-dependent patients: a comparison of clinical efficacy and cost.
Topics: Adult; Cocaine-Related Disorders; Cost-Benefit Analysis; Day Care, Medical; Female; Follow-Up Studie | 1999 |
The autonomy of mood disorders among cocaine-using methadone patients.
Topics: Adult; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Comorb | 1999 |
Relative potency of levo-alpha-acetylmethadol and methadone in humans under acute dosing conditions.
Topics: Adult; Analgesics, Opioid; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Heroin Depen | 1999 |
Revisiting the effectiveness of methadone treatment on crime reductions in the 1990s.
Topics: Adult; Alcoholism; Cocaine-Related Disorders; Crime; Data Interpretation, Statistical; Female; Heroi | 1999 |
Enhanced treatment outcomes for cocaine-using methadone patients.
Topics: Adult; Analysis of Variance; Cocaine-Related Disorders; Female; Humans; Male; Methadone; Middle Aged | 1999 |
Detection of illicit opioid and cocaine use in methadone maintenance treatment.
Topics: Adult; Analgesics, Opioid; Appointments and Schedules; Cocaine-Related Disorders; Female; Humans; Ma | 1999 |
Voucher-based reinforcement of cocaine abstinence in treatment-resistant methadone patients: effects of reinforcement magnitude.
Topics: Adult; Breath Tests; Cocaine-Related Disorders; Female; Humans; Male; Methadone; Narcotics; Psychiat | 1999 |
Forms of knowledge, cognitive impairment and drug abuse: a demonstration.
Topics: Adult; Cocaine-Related Disorders; Cognition Disorders; Female; Humans; Knowledge; Male; Methadone; M | 2000 |
Disulfiram treatment for cocaine dependence in methadone-maintained opioid addicts.
Topics: Cocaine-Related Disorders; Disulfiram; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Male; | 2000 |
Methadone dose increase and abstinence reinforcement for treatment of continued heroin use during methadone maintenance.
Topics: Adult; Behavior Therapy; Behavior, Addictive; Cocaine-Related Disorders; Combined Modality Therapy; | 2000 |
A path analysis of cognitive, affective, and behavioral predictors of treatment response in a methadone maintenance program.
Topics: Adult; Affect; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Internal-External Contr | 2000 |
A comparison of levomethadyl acetate, buprenorphine, and methadone for opioid dependence.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Cocaine-Related Disorders; Double-Blind Method; Drug Admin | 2000 |
A comparison of levomethadyl acetate, buprenorphine, and methadone for opioid dependence.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Cocaine-Related Disorders; Double-Blind Method; Drug Admin | 2000 |
A comparison of levomethadyl acetate, buprenorphine, and methadone for opioid dependence.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Cocaine-Related Disorders; Double-Blind Method; Drug Admin | 2000 |
A comparison of levomethadyl acetate, buprenorphine, and methadone for opioid dependence.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Cocaine-Related Disorders; Double-Blind Method; Drug Admin | 2000 |
The effectiveness of incentives in enhancing treatment attendance and drug abstinence in methadone-maintained pregnant women.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Cocaine-Related Disorders; Female; Heroin Depe | 2001 |
Effects of urine testing frequency on outcome in a methadone take-home contingency program.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Cocaine-Related Disorders; Female; Humans; Mal | 2001 |
Methadone tapering plus amantadine to detoxify heroin-dependent inpatients with or without an active cocaine use disorder: two randomised controlled trials.
Topics: Adolescent; Adult; Amantadine; Cocaine-Related Disorders; Comorbidity; Dose-Response Relationship, D | 2001 |
A reinforcement-based therapeutic workplace for the treatment of drug abuse: six-month abstinence outcomes.
Topics: Adult; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Methadone; Narcotics; Pregnancy | 2001 |
Voucher-based reinforcement of opiate plus cocaine abstinence in treatment-resistant methadone patients: effects of reinforcer magnitude.
Topics: Adult; Cocaine-Related Disorders; Drug Resistance; Female; Humans; Male; Methadone; Narcotics; Opioi | 2001 |
Shaping cocaine abstinence by successive approximation.
Topics: Adult; Behavior Therapy; Cocaine-Related Disorders; Female; Humans; Male; Methadone; Middle Aged; Mo | 2001 |
Social support and abstinence from opiates and cocaine during opioid maintenance treatment.
Topics: Adult; Aged; Analgesics, Opioid; Behavior Therapy; Chi-Square Distribution; Cocaine-Related Disorder | 2001 |
The brief abstinence test: effects of continued incentive availability on cocaine abstinence.
Topics: Adult; Analgesics, Opioid; Cocaine-Related Disorders; Female; Humans; Male; Methadone; Motivation; O | 2002 |
Ketoconazole increases cocaine and opioid use in methadone maintained patients.
Topics: Analysis of Variance; Antifungal Agents; Chi-Square Distribution; Cocaine-Related Disorders; Double- | 2002 |
Low-cost contingency management for treating cocaine- and opioid-abusing methadone patients.
Topics: Adult; Behavior Therapy; Cocaine-Related Disorders; Community Mental Health Services; Cost-Benefit A | 2002 |
Improving treatment engagement and outcomes for cocaine-using methadone patients.
Topics: Adult; Aged; Behavior Therapy; Cocaine-Related Disorders; Combined Modality Therapy; Crack Cocaine; | 2002 |
Utility of crossover designs in clinical trials: efficacy of desipramine vs. placebo in opioid-dependent cocaine abusers.
Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Buprenorphine; Clinical Trials as Topic | 2002 |
144 other studies available for methadone and Cocaine Abuse
| Article | Year |
|---|---|
The impact of marijuana use on cocaine use outcomes among patients in methadone maintenance treatment across five trials of contingency management.
Topics: Behavior Therapy; Cocaine; Cocaine-Related Disorders; Humans; Methadone; Opiate Substitution Treatme | 2022 |
Increased neural activity in the right dorsolateral prefrontal cortex during a risky decision-making task is associated with cocaine use in methadone-maintained patients.
Topics: Adult; Analgesics, Opioid; Cocaine; Cocaine-Related Disorders; Decision Making; Female; Follow-Up St | 2019 |
The psychiatrist at the centre of the opioid crisis.
Topics: Alcoholism; Cocaine-Related Disorders; Dopamine; Drug Overdose; Heroin Dependence; History, 20th Cen | 2020 |
Beyond abstinence and relapse: cluster analysis of drug-use patterns during treatment as an outcome measure for clinical trials.
Topics: Adult; Behavior Therapy; Clinical Trials as Topic; Cluster Analysis; Cocaine-Related Disorders; Fema | 2020 |
Polymorphisms in Stress-Related Genes Are Associated with Reduced Cocaine Abuse and Longer Retention in Methadone Maintenance Treatment for Opioid Use Disorder.
Topics: Analgesics, Opioid; Cocaine-Related Disorders; Humans; Methadone; Opiate Substitution Treatment; Opi | 2021 |
Beyond abstinence and relapse II: momentary relationships between stress, craving, and lapse within clusters of patients with similar patterns of drug use.
Topics: Affect; Buprenorphine; Cocaine-Related Disorders; Craving; Ecological Momentary Assessment; Female; | 2021 |
Contingency management treatment in cocaine using methadone maintained patients with and without legal problems.
Topics: Behavior Therapy; Cocaine; Cocaine-Related Disorders; Humans; Methadone; Opiate Substitution Treatme | 2017 |
Effect of computerized cognitive behavioral therapy on acquisition of coping skills among cocaine-dependent individuals enrolled in methadone maintenance.
Topics: Adaptation, Psychological; Adult; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Female; H | 2017 |
Predictors of heroin abstinence in opiate substitution therapy in heroin-only users and dual users of heroin and crack.
Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Cocaine-Related Disorders; Comorbidity; Female; Hero | 2018 |
Addressing discordant quantitative urine buprenorphine and norbuprenorphine levels: Case examples in opioid use disorder.
Topics: Adult; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Cocaine-Related Disorders; Drug Cont | 2018 |
Opioid substitution treatment and heroin dependent adolescents: reductions in heroin use and treatment retention over twelve months.
Topics: Adolescent; Buprenorphine; Cocaine-Related Disorders; Female; Follow-Up Studies; Heroin Dependence; | 2018 |
Gender-specific predictors of methadone treatment outcomes among African Americans at an urban clinic.
Topics: Academic Medical Centers; Adult; Age of Onset; Ambulatory Care Facilities; Analgesics, Opioid; Black | 2019 |
Defining and Predicting Opioid and Cocaine Treatment Response.
Topics: Adult; Cocaine-Related Disorders; Employment; Female; Heroin Dependence; Humans; Interpersonal Relat | 2019 |
Daily temporal patterns of heroin and cocaine use and craving: relationship with business hours regardless of actual employment status.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Analgesics, Opioid; Cocaine-Related Disorders; | 2013 |
Computerization of the therapeutic task of working through.
Topics: Cocaine-Related Disorders; Cognitive Behavioral Therapy; Female; Humans; Male; Methadone; Narcotics; | 2014 |
Severity and interference of chronic pain in methadone-maintained outpatients.
Topics: Adult; Age Factors; Baltimore; Benzodiazepines; Chronic Pain; Cocaine; Cocaine-Related Disorders; Co | 2014 |
Substance use and hepatitis C: an ecological momentary assessment study.
Topics: Adult; Affect; Antiviral Agents; Cocaine-Related Disorders; Craving; Female; Hepatitis C; Heroin Dep | 2014 |
Association between methadone dose and concomitant cocaine use in methadone maintenance treatment: a register-based study.
Topics: Adult; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Female; Heroin Dependence; Human | 2014 |
The impact of recent cocaine use on plasma levels of methadone and buprenorphine in patients with and without HIV-infection.
Topics: Adult; Anti-HIV Agents; Buprenorphine; Cocaine; Cocaine-Related Disorders; Drug Interactions; Female | 2015 |
Impact of incarceration on rates of methadone use in a community recruited cohort of injection drug users.
Topics: Adult; Cocaine-Related Disorders; Female; Housing; Humans; Male; Methadone; Narcotics; Opiate Substi | 2015 |
Gender-specific predictors of retention and opioid abstinence during methadone maintenance treatment.
Topics: Adult; Aged; Cannabinoids; Cocaine; Cocaine-Related Disorders; Female; Forecasting; Humans; Male; Ma | 2015 |
Factors associated with willingness to participate in a pharmacologic addiction treatment clinical trial among people who use drugs.
Topics: Adult; British Columbia; Cocaine-Related Disorders; Cohort Studies; Comorbidity; Crack Cocaine; Fema | 2015 |
Predictors of patient retention in methadone maintenance treatment.
Topics: Adolescent; Adult; Analgesics, Opioid; Cocaine-Related Disorders; Female; Humans; Male; Methadone; M | 2015 |
Sex effects in cocaine-using methadone patients randomized to contingency management interventions.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Behavior Therapy; Chi-Square Distribution; Cocaine- | 2015 |
Cognitive-behavioural therapy for heroin and cocaine use: Ecological momentary assessment of homework simplification and compliance.
Topics: Adolescent; Adult; Affect; Cocaine-Related Disorders; Cognition; Cognitive Behavioral Therapy; Ecolo | 2016 |
Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies.
Topics: Abscess; Adolescent; Adult; Alcoholism; Amphetamine-Related Disorders; Analgesics, Opioid; Australia | 2016 |
Real-time assessment of alcohol drinking and drug use in opioid-dependent polydrug users.
Topics: Adult; Affect; Alcohol Drinking; Alcoholism; Cocaine-Related Disorders; Cohort Studies; Craving; Fem | 2016 |
Methadone maintenance therapy and viral suppression among HIV-infected opioid users: The impacts of crack and injection cocaine use.
Topics: Adult; Analgesics, Opioid; Canada; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Female; HIV In | 2016 |
The impact of benzodiazepine use on methadone maintenance treatment outcomes.
Topics: Adult; Alcoholism; Benzodiazepines; Cocaine-Related Disorders; Comorbidity; Depressive Disorder; Dia | 2008 |
Steady-state methadone blocks cocaine seeking and cocaine-induced gene expression alterations in the rat brain.
Topics: Acoustic Stimulation; Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Brain; Co | 2009 |
Marriage and relationship closeness as predictors of cocaine and heroin use.
Topics: Adult; Aged; Cocaine-Related Disorders; Couples Therapy; Female; Heroin Dependence; Humans; Male; Me | 2009 |
[Methadone: Medical treatment or dealing?].
Topics: Adult; Cocaine-Related Disorders; Crime; Female; Humans; Methadone; Narcotics; Prescription Drugs; S | 2008 |
Real-time electronic diary reports of cue exposure and mood in the hours before cocaine and heroin craving and use.
Topics: Adult; Affect; Ambulatory Care; Cocaine-Related Disorders; Combined Modality Therapy; Computers, Han | 2009 |
Gender Differences Among In- and Out-of-Treatment Opioid-Addicted Individuals.
Topics: Adolescent; Adult; Age of Onset; Analgesics, Opioid; Baltimore; Cocaine-Related Disorders; Crime; Fe | 2009 |
Correlates of stimulant treatment outcome across treatment modalities.
Topics: Adult; Alcoholism; Behavior; Central Nervous System Stimulants; Cocaine-Related Disorders; Cognition | 2009 |
Interdependent group contingency management for cocaine-dependent methadone maintenance patients.
Topics: Adult; Behavior Therapy; Choice Behavior; Cocaine-Related Disorders; Community Mental Health Service | 2008 |
Scaling-up interim methadone maintenance: treatment for 1,000 heroin-addicted individuals.
Topics: Adult; Cocaine-Related Disorders; Directive Counseling; Emergency Medical Services; Female; Heroin D | 2009 |
Cocaine craving and use during daily life.
Topics: Adult; Affect; Behavior, Addictive; Cocaine-Related Disorders; Cohort Studies; Female; Humans; Longi | 2009 |
Effectiveness of community treatments for heroin and crack cocaine addiction in England: a prospective, in-treatment cohort study.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Cocaine-Related Disorders; Community Mental Health Service | 2009 |
Tobacco, cocaine, and heroin: Craving and use during daily life.
Topics: Adult; Behavior, Addictive; Cocaine-Related Disorders; Computers, Handheld; Female; Heroin Dependenc | 2010 |
Forensic aspects of reckless prescribing.
Topics: Cocaine-Related Disorders; Crime; Humans; Methadone; Narcotics; Prescriptions; United Kingdom | 2009 |
Investigating the effects of San Francisco's Treatment on Demand Initiative on a publicly-funded substance abuse treatment system: a time series analysis.
Topics: Adolescent; Adult; Cocaine-Related Disorders; Data Interpretation, Statistical; Ethnicity; Female; H | 2009 |
High dose versus moderate dose methadone maintenance: is there a better outcome?
Topics: Adult; Aged; Analgesics, Opioid; Cocaine-Related Disorders; Female; Georgia; Humans; Male; Medical R | 2009 |
Infant autonomic functioning and neonatal abstinence syndrome.
Topics: Adult; Apgar Score; Autonomic Nervous System; Cocaine-Related Disorders; Data Interpretation, Statis | 2010 |
Motivational incentives research in the National Drug Abuse Treatment Clinical Trials Network.
Topics: Adult; Amphetamine-Related Disorders; Cocaine-Related Disorders; Counseling; Female; Follow-Up Studi | 2010 |
Using a latent variable approach to inform gender and racial/ethnic differences in cocaine dependence: a National Drug Abuse Treatment Clinical Trials Network study.
Topics: Adult; Bias; Clinical Trials as Topic; Cocaine-Related Disorders; Community Health Services; Data Co | 2010 |
Nasal carriage prevalence of meticillin resistant (MRSA) and meticillin sensitive (MSSA) Staphylococcus aureus for subjects attending a Dublin methadone clinic.
Topics: Carrier State; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Ireland; Male; Methadon | 2010 |
Daily life hour by hour, with and without cocaine: an ecological momentary assessment study.
Topics: Adult; Affect; Cocaine; Cocaine-Related Disorders; Cohort Studies; Computers, Handheld; Female; Hero | 2010 |
Methadone maintenance treatment: a protective factor for cocaine injection in a street-recruited cohort of heroin users.
Topics: Cocaine; Cocaine-Related Disorders; Cohort Studies; Female; Heroin; Heroin Dependence; Humans; Injec | 2010 |
Resets do not appear to increase the rate of adverse events or prolong relapse in voucher-based reinforcement therapy.
Topics: Adult; Cocaine-Related Disorders; Female; Humans; Male; Methadone; Middle Aged; Proportional Hazards | 2010 |
Analysis of the impact of treatment setting on outcomes from methadone treatment.
Topics: Benzodiazepines; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Follow-Up Studies; Her | 2010 |
Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Delayed-Action Preparations; Disease Models, Ani | 2010 |
Prenatal methadone exposure, meconium biomarker concentrations and neonatal abstinence syndrome.
Topics: Adult; Analgesics, Opioid; Cocaine; Cocaine-Related Disorders; Female; Gestational Age; Humans; Infa | 2010 |
Stress in the daily lives of cocaine and heroin users: relationship to mood, craving, relapse triggers, and cocaine use.
Topics: Adult; Affect; Cocaine-Related Disorders; Computers, Handheld; Female; Heroin Dependence; Humans; Ma | 2011 |
Oral fluid results compared to self reports of recent cocaine and heroin use by methadone maintenance patients.
Topics: Cocaine; Cocaine-Related Disorders; Codeine; Heroin; Heroin Dependence; Humans; Methadone; Morphine; | 2012 |
Treatment-like steady-state methadone in rats interferes with incubation of cocaine sensitization and associated alterations in gene expression.
Topics: Analgesics, Opioid; Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopa | 2012 |
[Abstinence from cocaine after long-term addiction].
Topics: Adaptation, Psychological; Adult; Behavior, Addictive; Cocaine-Related Disorders; Comorbidity; Crack | 2011 |
Former heroin addicts with or without a history of cocaine dependence are more impulsive than controls.
Topics: Adult; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Impulsive Behavior; Male; Metha | 2012 |
Maintenance of reinforcement to address the chronic nature of drug addiction.
Topics: Analgesics, Opioid; Baltimore; Clinical Trials as Topic; Cocaine-Related Disorders; Female; Humans; | 2012 |
Sex differences in cocaine/heroin users: drug-use triggers and craving in daily life.
Topics: Adolescent; Adult; Affect; Aged; Cocaine-Related Disorders; Cues; Diagnostic and Statistical Manual | 2013 |
Antisocial personality disorder is associated with receipt of physical disability benefits in substance abuse treatment patients.
Topics: Adult; Antisocial Personality Disorder; Cocaine-Related Disorders; Confidence Intervals; Disability | 2013 |
Methadone treatment outcomes appear mainly unaffected by cannabis use.
Topics: Analgesics, Opioid; Cocaine-Related Disorders; Heroin Dependence; Humans; Marijuana Abuse; Methadone | 2003 |
The National Treatment Outcome Research Study (NTORS): 4-5 year follow-up results.
Topics: Alcoholism; Amphetamines; Analgesics, Opioid; Cocaine-Related Disorders; Cohort Studies; Crime; Engl | 2003 |
Methadone treatment induces attenuation of cerebrovascular deficits associated with the prolonged abuse of cocaine and heroin.
Topics: Adult; Analysis of Variance; Anterior Cerebral Artery; Cerebrovascular Circulation; Cerebrovascular | 2003 |
Spiritual beliefs, world assumptions, and HIV risk behavior among heroin and cocaine users.
Topics: Adult; Cocaine-Related Disorders; Culture; Female; Heroin Dependence; HIV Seropositivity; Humans; Ma | 2003 |
[Vaccine, methadone and zebrafish].
Topics: Animals; Cocaine-Related Disorders; Disease Models, Animal; Methadone; Narcotics; Vaccines; Zebrafis | 2003 |
Relationship between prescribing and risk of opiate overdose among drug users in and out of maintenance treatment.
Topics: Adult; Alcoholic Intoxication; Benzodiazepines; Causality; Cocaine-Related Disorders; Comorbidity; C | 2004 |
Predictors of drug treatment re-entry following relapse to cocaine use in DATOS.
Topics: Adult; Ambulatory Care; Black People; Cocaine-Related Disorders; Female; Follow-Up Studies; Humans; | 2003 |
Recovery from opioid addiction in DATOS.
Topics: Adult; Alcoholism; Ambulatory Care; Cocaine-Related Disorders; Comorbidity; Crime; Female; Follow-Up | 2003 |
French version of the addiction severity index (5th Edition): validity and reliability among Swiss opiate-dependent patients. French validation of the Addiction Severity Index.
Topics: Adult; Alcoholism; Cocaine-Related Disorders; Comorbidity; Cross-Cultural Comparison; Female; Heroin | 2004 |
Validation of the Cozart microplate EIA for cocaine and metabolites in oral fluid.
Topics: Algorithms; Antibody Specificity; Cocaine; Cocaine-Related Disorders; Cross Reactions; Enzyme-Linked | 2004 |
Methadone maintenance program in a Swiss perinatal center: (I): Management and outcome of 89 pregnancies.
Topics: Adult; Birth Weight; Cocaine-Related Disorders; Cohort Studies; Dose-Response Relationship, Drug; Dr | 2005 |
[Reply concerning the article "Is methadone maintenance provided by private practitioners effective?' by R. Stohler et al. in SPM 49 (2004), 276-80].
Topics: Cocaine-Related Disorders; Family Practice; Heroin Dependence; Humans; Methadone; Narcotics; Patient | 2005 |
[Methadone and sleep apnea syndrome].
Topics: Adult; Brain; Clonidine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug Administr | 2005 |
Neuropsychological functioning in methadone maintenance patients versus abstinent heroin abusers.
Topics: Adult; Alcoholism; Cocaine-Related Disorders; Cognition Disorders; Female; Heroin Dependence; Humans | 2005 |
Prevalence and correlates of cocaine physical dependence subtypes using the DSM-IV in outpatients receiving opioid agonist medication.
Topics: Adult; Ambulatory Care; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disor | 2005 |
Factors associated with methadone maintenance therapy use among a cohort of polysubstance using injection drug users in Vancouver.
Topics: Adult; Canada; Catchment Area, Health; Cocaine-Related Disorders; Cohort Studies; Drug Overdose; Fac | 2005 |
Adverse events among patients in a behavioral treatment trial for heroin and cocaine dependence: effects of age, race, and gender.
Topics: Administration, Oral; Adult; Ambulatory Care; Black People; Cocaine-Related Disorders; Cognitive Beh | 2005 |
A comparison of voucher-delivery schedules for the initiation of cocaine abstinence.
Topics: Adult; Cocaine-Related Disorders; Female; Humans; Male; Methadone; Middle Aged; Motivation; Patient | 2005 |
Patterns of heroin, cocaine, and alcohol abuse during long-term methadone maintenance treatment.
Topics: Adult; Alcoholism; Ambulatory Care; Cocaine-Related Disorders; Cross-Sectional Studies; Female; Hero | 2005 |
Effectiveness of drug and alcohol counselling during methadone treatment: content, frequency, and duration of counselling and association with substance use outcomes.
Topics: Adult; Alcohol-Related Disorders; Cocaine-Related Disorders; Cohort Studies; Counseling; Female; Fol | 2006 |
Determinants of health-related quality of life of opiate users at entry to low-threshold methadone programs.
Topics: Adolescent; Adult; Child Abuse; Child Abuse, Sexual; Cocaine-Related Disorders; Comorbidity; Female; | 2006 |
Opioid substitution treatment reduces substance use equivalently in patients with and without posttraumatic stress disorder.
Topics: Adult; Aged; Alcoholism; Cocaine-Related Disorders; Combat Disorders; Comorbidity; Female; Follow-Up | 2006 |
High methadone dose significantly reduces cocaine use in methadone maintenance treatment (MMT) patients.
Topics: Adolescent; Adult; Analgesics, Opioid; Cocaine; Cocaine-Related Disorders; Dose-Response Relationshi | 2006 |
Pills for speedballing or cocaine dependence.
Topics: Bupropion; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Humans; Methadone; Narcotics; Opio | 2006 |
Glucocorticoid negative feedback in methadone-maintained former heroin addicts with ongoing cocaine dependence: dose-response to dexamethasone suppression.
Topics: Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Cocaine-Related Disorders; Comorbidity; Dexame | 2006 |
Gender differences and pregnant women in a methadone maintenance treatment (MMT) clinic.
Topics: Adult; Age Factors; Cocaine-Related Disorders; Cohort Studies; Comorbidity; Emigration and Immigrati | 2006 |
Relapse to opioid use after treatment of chronic hepatitis C with pegylated interferon and ribavirin.
Topics: Antiviral Agents; Behavior, Addictive; Cocaine-Related Disorders; Comorbidity; Drug Administration S | 2006 |
Adolescent and young adult heroin patients: drug use and success in methadone maintenance treatment.
Topics: Adolescent; Adult; Cocaine-Related Disorders; Demography; Drug Interactions; Female; Heroin Dependen | 2006 |
Depression in methadone maintenance treatment patients: rate and risk factors.
Topics: Adult; Benzodiazepines; Brief Psychiatric Rating Scale; Cocaine; Cocaine-Related Disorders; Comorbid | 2007 |
Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Cocaine-Related Disorders; Cognition Disorders | 2006 |
Comparison between heroin and heroin-cocaine polyabusers: a psychopathological study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Interactions; Female; He | 2006 |
What do we get for our money? Cost-effectiveness of adding contingency management.
Topics: Adolescent; Adult; Aged; Cocaine-Related Disorders; Cost-Benefit Analysis; Female; Humans; Male; Met | 2007 |
Different components of opioid-substitution treatment predict outcomes of patients with and without a parent with substance-use problems.
Topics: Adult; Alcoholism; Child; Child of Impaired Parents; Cocaine-Related Disorders; Combined Modality Th | 2007 |
Mechanisms of prescription drug diversion among drug-involved club- and street-based populations.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Analgesics, Opioid; Antiretroviral Therapy, Highly | 2007 |
The impact of ongoing illicit drug use on methadone adherence in illicit drug users receiving treatment for HIV in a directly observed therapy program.
Topics: Amphetamine-Related Disorders; Antiretroviral Therapy, Highly Active; Benzodiazepines; Cocaine-Relat | 2007 |
Alcohol and cocaine use and abuse among opioid addicts engaged in a methadone maintenance treatment program.
Topics: Adolescent; Adult; Alcoholism; Catchment Area, Health; Cocaine-Related Disorders; Demography; Female | 2007 |
Body composition, gender, and illicit drug use in an urban cohort.
Topics: Baltimore; Black People; Body Composition; Body Mass Index; Cocaine-Related Disorders; Comorbidity; | 2007 |
Professional demeanor of chronically unemployed cocaine-dependent methadone patients in a therapeutic workplace.
Topics: Adult; Cocaine-Related Disorders; Demography; Female; Heroin Dependence; Humans; Male; Methadone; Mi | 2007 |
A longitudinal investigation into excess risk for blood-borne infection among young injection drug users (IUDs).
Topics: Adult; Age Factors; Amphetamine-Related Disorders; British Columbia; Cocaine-Related Disorders; Comm | 2007 |
Rethinking approaches to risk reduction for injection drug users: differences in drug type affect risk for HIV and hepatitis C virus infection through drug-injecting networks.
Topics: Adolescent; Adult; Age of Onset; Cocaine-Related Disorders; Cross-Sectional Studies; Female; Hepatit | 2007 |
Intravenous and intranasal heroin-dependent treatment-seekers: characteristics and treatment outcome.
Topics: Adult; Cocaine-Related Disorders; Drug Administration Schedule; Female; Heroin; Heroin Dependence; H | 2007 |
Methadone maintenance treatment (MMT) in general practice or in specialized centers: profile of patients in the Swiss Canton of Vaud.
Topics: Adult; AIDS Serodiagnosis; Antipsychotic Agents; Cocaine-Related Disorders; Cross-Sectional Studies; | 2007 |
Prescription opioid use, misuse, and diversion among street drug users in New York City.
Topics: Administration, Intranasal; Adult; Aged; Analgesics, Opioid; Buprenorphine; Cocaine-Related Disorder | 2008 |
Over- and underreporting of recent drug use in subjects entering an inpatient detoxification unit.
Topics: Adolescent; Adult; Benzodiazepines; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; In | 2008 |
Alcohol and HIV sexual risk behaviors among injection drug users.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Cocaine-Related Disorders; Cross-Sectional Studies; Femal | 2008 |
Evaluation of ongoing oxycodone abuse among methadone-maintained patients.
Topics: Adolescent; Adult; Cocaine-Related Disorders; Enzyme Multiplied Immunoassay Technique; Female; Human | 2008 |
Psychosocial antecedents of needle/syringe disinfection by drug users: a theory-based prospective analysis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Cocaine-Related Disorders; Disinfection; Female; Health E | 1997 |
A preliminary investigation of lamotrigine for cocaine abuse in HIV-seropositive patients.
Topics: Adult; Buprenorphine; Cocaine-Related Disorders; Combined Modality Therapy; Dose-Response Relationsh | 1998 |
Differentiation in the Amsterdam methadone dispensing circuit: determinants of methadone dosage and site of methadone prescription.
Topics: Adult; Ambulatory Care; Cocaine-Related Disorders; Cohort Studies; Female; Heroin Dependence; Humans | 1998 |
In contrast to cocaine, prenatal exposure to methadone does not produce detectable alterations in the developing mouse brain.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Brain; Cerebral Cortex; Cocaine; Cocaine-Related Disor | 1998 |
Cocaine use early in treatment predicts outcome in a behavioral treatment program.
Topics: Adult; Behavior Therapy; Cocaine; Cocaine-Related Disorders; Female; Forecasting; Humans; Longitudin | 1998 |
Effects of "binge" use of intravenous cocaine in methadone-maintained individuals.
Topics: Adult; Affect; Blood Pressure; Cocaine; Cocaine-Related Disorders; Depression; Heart Rate; Humans; I | 1998 |
Choreoathetoid movements associated with rapid adjustment to methadone.
Topics: Adult; Athetosis; Chorea; Cocaine-Related Disorders; Heroin Dependence; Humans; Male; Methadone; Nar | 1998 |
Temporal patterns of heroin and cocaine use among methadone patients.
Topics: Adult; Age Factors; Analysis of Variance; Cluster Analysis; Cocaine-Related Disorders; Crime; Female | 1998 |
Gender differences in psychiatric comorbidity among cocaine-using opiate addicts.
Topics: Adult; Alcoholism; Anxiety Disorders; Cocaine-Related Disorders; Comorbidity; Female; Humans; Male; | 1998 |
Drug use predictors of partner violence in opiate-dependent women.
Topics: Adolescent; Adult; Alcohol Drinking; Battered Women; Child; Child, Preschool; Cocaine-Related Disord | 1998 |
Changes in HIV risk behaviors among cocaine-using methadone patients.
Topics: Adult; Cocaine-Related Disorders; Female; HIV Infections; Humans; Male; Methadone; Narcotics; Needle | 1998 |
Methadone treatment by general practitioners in Amsterdam.
Topics: Cocaine-Related Disorders; Health Policy; Heroin Dependence; Humans; Methadone; Narcotics; Netherlan | 1995 |
Program quality effects on patient outcomes during methadone maintenance: a study of 17 clinics.
Topics: Adult; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Male; Methadone; Narcotics; New | 1999 |
Monitoring cocaine use in substance-abuse-treatment patients by sweat and urine testing.
Topics: Adolescent; Adult; Aged; Cocaine; Cocaine-Related Disorders; Enzyme Multiplied Immunoassay Technique | 1999 |
HIV risk reduction in outpatient drug abuse treatment: individual and geographic differences.
Topics: Adult; Alcoholism; Antisocial Personality Disorder; Cities; Cocaine-Related Disorders; Female; HIV I | 1999 |
Prior treatment history and its impact on criminal recidivism.
Topics: Adult; Alcoholism; Antisocial Personality Disorder; Cocaine-Related Disorders; Combined Modality The | 1999 |
Should cocaine-abusing, buprenorphine-maintained patients receive auricular acupuncture? Findings from an acute effects study.
Topics: Acupuncture, Ear; Adult; Analgesics, Opioid; Buprenorphine; Cocaine-Related Disorders; Female; Human | 1999 |
Cocaine abuse sharply reduced in an effective methadone maintenance program.
Topics: Adult; Aged; Catchment Area, Health; Cocaine-Related Disorders; Drug Administration Schedule; Female | 1999 |
Hardcore drug users claim to be occasional users: drug use frequency underreporting.
Topics: Adult; Bias; Cocaine-Related Disorders; Deception; Female; Heroin Dependence; Humans; Male; Methadon | 2000 |
The brief abstinence test: voucher-based reinforcement of cocaine abstinence.
Topics: Adult; Analysis of Variance; Behavior Therapy; Chi-Square Distribution; Cocaine-Related Disorders; F | 2000 |
Comparison of patient self-reports and urinalysis results obtained under naturalistic methadone treatment conditions.
Topics: Adult; Cocaine-Related Disorders; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Pa | 2000 |
Treatment services received by supplemental security income drug and alcoholic clients.
Topics: Adult; Alcoholism; Cocaine-Related Disorders; Female; Health Services Needs and Demand; Humans; Male | 2000 |
Community reinforcement approach for combined opioid and cocaine dependence. Patterns of engagement in alternate activities.
Topics: Adult; Buprenorphine; Clinical Trials as Topic; Cocaine-Related Disorders; Community Networks; Couns | 2000 |
Depression among needle exchange program and methadone maintenance clients.
Topics: Adult; Cocaine-Related Disorders; Cohort Studies; Comorbidity; Cross-Sectional Studies; Depressive D | 2000 |
Homelessness and gender in out-of-treatment drug users.
Topics: Acquired Immunodeficiency Syndrome; Adult; Black or African American; Cocaine-Related Disorders; Cra | 2000 |
Posttraumatic stress disorder and short-term outcome in early methadone treatment.
Topics: Adult; Analysis of Variance; Cocaine-Related Disorders; Diagnosis, Differential; Diagnosis, Dual (Ps | 2000 |
Importance of identifying cocaine and alcohol dependent methadone clients.
Topics: Adult; Aged; Alcoholism; Cocaine-Related Disorders; Counseling; Female; Humans; Male; Methadone; Mid | 2000 |
The effect of stimulant and sedative use on treatment outcome of patients admitted to methadone maintenance treatment.
Topics: Adult; Central Nervous System Stimulants; Cocaine-Related Disorders; Female; Follow-Up Studies; Huma | 2000 |
The Key Extended Entry Program (KEEP): from the community side of the bridge.
Topics: Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Male; Methadone; Narcotics; Prisoners; | 2001 |
Family history influence on drug abuse severity and treatment outcome.
Topics: Adult; Chi-Square Distribution; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Logist | 2001 |
Altered HPA axis responsivity to metyrapone testing in methadone maintained former heroin addicts with ongoing cocaine addiction.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Cocaine-Related Disorders; Female; Heroin Dependence | 2001 |
Drug use, HIV-related risk behaviors and dropout status of new admissions and re-admissions to methadone treatment.
Topics: Adult; Cocaine-Related Disorders; Crack Cocaine; Cross-Sectional Studies; Female; Follow-Up Studies; | 2001 |
Detection of opiate use in a methadone maintenance treatment population with the CEDIA 6-acetylmorphine and CEDIA DAU opiate assays.
Topics: Adolescent; Adult; Cocaine-Related Disorders; Codeine; False Positive Reactions; Female; Gas Chromat | 2001 |
[Cocaine abuse in maintenance therapy with methadone in narcotic dependent patients].
Topics: Adolescent; Adult; Ambulatory Care; Anti-Anxiety Agents; Austria; Benzodiazepines; Cocaine-Related D | 2001 |
Oral motor parafunctions among heavy drug addicts and their effects on signs and symptoms of temporomandibular disorders.
Topics: Adolescent; Adult; Bruxism; Case-Control Studies; Chi-Square Distribution; Cocaine-Related Disorders | 2001 |
Conservative management with naltrexone of an iatrogenic methadone overdose in an opiate-naive patient.
Topics: Alcoholism; Cocaine-Related Disorders; Diagnosis, Dual (Psychiatry); Drug Overdose; Humans; Male; Me | 2002 |
Cognitive impairment in methadone maintenance patients.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Cognition Disorders; Concept Formation; Female; Heroin; H | 2002 |