Page last updated: 2024-10-30

methadone and Co-infection

methadone has been researched along with Co-infection in 18 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Research Excerpts

ExcerptRelevanceReference
"To assess trends and related factors in HIV and/or hepatitis C virus (HCV) antibody testing and infection among injection drug users (IDUs) newly entering methadone maintenance treatment (MMT) in Guangdong Province, China."7.85Trends and factors in human immunodeficiency virus and/or hepatitis C virus testing and infection among injection drug users newly entering methadone maintenance treatment in Guangdong Province, China 2006-2013: a consecutive cross sectional study. ( Chen, W; Ling, L; Liu, Y; Zou, X, 2017)
"The aim of this study was to characterize the epidemiology and disease related to hepatitis C in a population attending a low-threshold methadone program."7.85Hepatitis C in a Mobile Low-Threshold Methadone Program. ( Água-Doce, I; Balsa, C; Belo, E; Coutinho, R; Lopes, P; Loureiro, R; Martins, HC; Pádua, E; Pereira, C; Silva, MJ, 2017)
"Methadone treatment (exposure) was self-reported and severe FI (outcome) was measured using the Household Food Security Survey Module."5.48Methadone treatment, severe food insecurity, and HIV-HCV co-infection: A propensity score matching analysis. ( Cooper, C; Cox, J; Hamelin, AM; Harper, S; Klein, MB; McLinden, T; Moodie, EEM; Rossi, C; Rourke, SB; Walmsley, SL, 2018)
"A methadone maintenance treatment (MMT) program to curb the dual epidemics of HIV/AIDS and drug use has been administered by China since 2004."5.46Spatial distribution of HIV, HCV, and co-infections among drug users in the southwestern border areas of China (2004-2014): a cohort study of a national methadone maintenance treatment program. ( He, C; Huang, W; Lan, G; Li, C; Li, M; Li, R; Liang, N; Peng, Z; Shen, Z; Tang, X; Zhong, F, 2017)
"The diagnosis of pulmonary tuberculosis associated with Kaposi's sarcoma and immunosuppression caused by HIV was retained."5.46[TB/HIV co-infection associated with Kaposi's sarcoma under opioid substitution treatment using methadone: about a case]. ( Cisse Diallo, VMP; Deguenonvo, LF; Dièye, A; Diop Nyafouna, SA; Diop, M; Ka, D; Lakhe, NA; Massaly, A; Mbaye, KD; Ndiaye, I; Ndour, CT; Seydi, M; Thioub, D, 2017)
"Patients with opioid use disorders on opioid agonist therapy (OAT) have lower pain tolerance compared to controls."5.42Hepatitis C virus infection and pain sensitivity in patients on methadone or buprenorphine maintenance therapy for opioid use disorders. ( Alford, DP; Cheng, DM; Edwards, RR; Liebschutz, JM; Lira, MC; Mao, J; Samet, JH; Tsui, JI; Winter, MR, 2015)
"Methadone maintenance treatment (MMT) has been available in Guangdong province, China since 2006."5.39High prevalence of HIV, HCV and tuberculosis and associated risk behaviours among new entrants of methadone maintenance treatment clinics in Guangdong Province, China. ( Chen, W; Ling, L; Zhang, D; Zhang, L; Zou, X, 2013)
"To assess trends and related factors in HIV and/or hepatitis C virus (HCV) antibody testing and infection among injection drug users (IDUs) newly entering methadone maintenance treatment (MMT) in Guangdong Province, China."3.85Trends and factors in human immunodeficiency virus and/or hepatitis C virus testing and infection among injection drug users newly entering methadone maintenance treatment in Guangdong Province, China 2006-2013: a consecutive cross sectional study. ( Chen, W; Ling, L; Liu, Y; Zou, X, 2017)
"The aim of this study was to characterize the epidemiology and disease related to hepatitis C in a population attending a low-threshold methadone program."3.85Hepatitis C in a Mobile Low-Threshold Methadone Program. ( Água-Doce, I; Balsa, C; Belo, E; Coutinho, R; Lopes, P; Loureiro, R; Martins, HC; Pádua, E; Pereira, C; Silva, MJ, 2017)
"To describe potential drug-drug interactions in the area of HIV/hepatitis C virus (HCV) coinfection and injection drug use, including those between antiretrovirals (ARVs), direct-acting antivirals (DAAs), and opioid-agonist therapy, and to supply a practical approach to their management."2.52Drug-Drug Interactions With Antiviral Agents in People Who Inject Drugs Requiring Substitution Therapy. ( Christensen, S; Gillessen, A; Hanhoff, N; Meemken, L; Tseng, A, 2015)
"Methadone maintenance treatment (MMT) was implemented in China since 2004."2.48HIV and HCV prevalence among entrants to methadone maintenance treatment clinics in China: a systematic review and meta-analysis. ( Chow, EP; Liang, Y; Wang, Y; Wilson, DP; Zhang, L; Zhuang, X, 2012)
"Methadone treatment (exposure) was self-reported and severe FI (outcome) was measured using the Household Food Security Survey Module."1.48Methadone treatment, severe food insecurity, and HIV-HCV co-infection: A propensity score matching analysis. ( Cooper, C; Cox, J; Hamelin, AM; Harper, S; Klein, MB; McLinden, T; Moodie, EEM; Rossi, C; Rourke, SB; Walmsley, SL, 2018)
"A methadone maintenance treatment (MMT) program to curb the dual epidemics of HIV/AIDS and drug use has been administered by China since 2004."1.46Spatial distribution of HIV, HCV, and co-infections among drug users in the southwestern border areas of China (2004-2014): a cohort study of a national methadone maintenance treatment program. ( He, C; Huang, W; Lan, G; Li, C; Li, M; Li, R; Liang, N; Peng, Z; Shen, Z; Tang, X; Zhong, F, 2017)
"The diagnosis of pulmonary tuberculosis associated with Kaposi's sarcoma and immunosuppression caused by HIV was retained."1.46[TB/HIV co-infection associated with Kaposi's sarcoma under opioid substitution treatment using methadone: about a case]. ( Cisse Diallo, VMP; Deguenonvo, LF; Dièye, A; Diop Nyafouna, SA; Diop, M; Ka, D; Lakhe, NA; Massaly, A; Mbaye, KD; Ndiaye, I; Ndour, CT; Seydi, M; Thioub, D, 2017)
"Patients with opioid use disorders on opioid agonist therapy (OAT) have lower pain tolerance compared to controls."1.42Hepatitis C virus infection and pain sensitivity in patients on methadone or buprenorphine maintenance therapy for opioid use disorders. ( Alford, DP; Cheng, DM; Edwards, RR; Liebschutz, JM; Lira, MC; Mao, J; Samet, JH; Tsui, JI; Winter, MR, 2015)
"Methadone maintenance treatment (MMT) has been available in Guangdong province, China since 2006."1.39High prevalence of HIV, HCV and tuberculosis and associated risk behaviours among new entrants of methadone maintenance treatment clinics in Guangdong Province, China. ( Chen, W; Ling, L; Zhang, D; Zhang, L; Zou, X, 2013)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's17 (94.44)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Pes, F1
Onali, S1
Balestrieri, C1
Angioni, G1
Ortu, F1
Piano, P1
Lucia, B1
Scioscia, R1
Princic, E1
Bolliri, AC1
Casale, M1
Cola, A1
Conti, M1
Peddis, L1
Serra, G1
Vacca, S1
Loi, M1
Urru, E1
Murru, C1
Matta, L1
Del Giacco, S1
Babudieri, S1
Maida, I1
Chessa, L1
Roncero, C1
Fuster, D1
Palma-Álvarez, RF1
Rodriguez-Cintas, L1
Martinez-Luna, N1
Álvarez, FJ1
Liu, Y2
Zou, X2
Chen, W2
Ling, L2
Li, M1
Li, R1
Shen, Z1
Li, C1
Liang, N1
Peng, Z1
Huang, W1
He, C1
Zhong, F1
Tang, X1
Lan, G1
Cisse Diallo, VMP1
Deguenonvo, LF1
Mbaye, KD1
Ka, D1
Lakhe, NA1
Ndiaye, I1
Thioub, D1
Diop Nyafouna, SA1
Massaly, A1
Dièye, A1
Diop, M1
Ndour, CT1
Seydi, M1
Schackman, BR1
Gutkind, S1
Morgan, JR1
Leff, JA1
Behrends, CN1
Delucchi, KL1
McKnight, C1
Perlman, DC1
Masson, CL1
Linas, BP1
McLinden, T1
Moodie, EEM1
Hamelin, AM1
Harper, S1
Rossi, C1
Walmsley, SL1
Rourke, SB1
Cooper, C1
Klein, MB1
Cox, J1
Yi, S1
Mun, P1
Chhoun, P1
Chann, N1
Tuot, S1
Mburu, G1
Zhang, L2
Zhang, D1
Marco, A1
Gallego, C1
Caylà, JA1
Zhou, YB1
Liang, S1
Wang, QX1
Gong, YH1
Nie, SJ1
Nan, L1
Yang, AH1
Liao, Q1
Song, XX1
Jiang, QW1
Meemken, L1
Hanhoff, N1
Tseng, A1
Christensen, S1
Gillessen, A1
Tsui, JI1
Lira, MC1
Cheng, DM1
Winter, MR1
Alford, DP1
Liebschutz, JM1
Mao, J1
Edwards, RR1
Samet, JH1
Gervasoni, C1
Peri, AM1
Cattaneo, D1
Baldelli, S1
Rizzardini, G1
Milazzo, L1
Pu, L1
Su, Y1
Wang, G1
Bai, J1
Silva, MJ1
Pereira, C1
Loureiro, R1
Balsa, C1
Lopes, P1
Água-Doce, I1
Belo, E1
Martins, HC1
Coutinho, R1
Pádua, E1
Zhuang, X1
Liang, Y1
Chow, EP1
Wang, Y1
Wilson, DP1
Yen, YF1
Yen, MY1
Su, LW1
Li, LH1
Chuang, P1
Jiang, XR1
Deng, CY1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Single Arm, Open-label 96 Week Observational Trial of the Tolerability, Adherence and Efficacy of a Dolutegravir/Abacavir/Lamivudine Single Tablet Regimen in HIV-1 Antibody Positive People Living With HIV With a History of Injection Drug Us[NCT02659761]Phase 450 participants (Anticipated)Interventional2016-11-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for methadone and Co-infection

ArticleYear
Drug-Drug Interactions With Antiviral Agents in People Who Inject Drugs Requiring Substitution Therapy.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:7

    Topics: Analgesics, Opioid; Antiviral Agents; Coinfection; Drug Interactions; Hepatitis C; HIV Infections; H

2015
HIV and HCV prevalence among entrants to methadone maintenance treatment clinics in China: a systematic review and meta-analysis.
    BMC infectious diseases, 2012, Jun-08, Volume: 12

    Topics: China; Coinfection; Hepatitis C; HIV Infections; Methadone; Opiate Substitution Treatment; Prevalenc

2012

Trials

1 trial available for methadone and Co-infection

ArticleYear
Cost-effectiveness of hepatitis C screening and treatment linkage intervention in US methadone maintenance treatment programs.
    Drug and alcohol dependence, 2018, 04-01, Volume: 185

    Topics: Adult; Antiviral Agents; Coinfection; Cost-Benefit Analysis; Female; Hepatitis C, Chronic; Humans; M

2018

Other Studies

15 other studies available for methadone and Co-infection

ArticleYear
HCV treatment in Sardinian HIV-HCV coinfected patients: a real-life perspective study on safety, efficacy, and immune reconstitution.
    Expert review of anti-infective therapy, 2022, Volume: 20, Issue:11

    Topics: Antiviral Agents; Coinfection; Female; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Im

2022
HIV And HCV infection among opiate-dependent patients and methadone doses: the PROTEUS study.
    AIDS care, 2017, Volume: 29, Issue:12

    Topics: Adult; Analgesics, Opioid; Anti-Retroviral Agents; Coinfection; Comorbidity; Dose-Response Relations

2017
Trends and factors in human immunodeficiency virus and/or hepatitis C virus testing and infection among injection drug users newly entering methadone maintenance treatment in Guangdong Province, China 2006-2013: a consecutive cross sectional study.
    BMJ open, 2017, Jul-13, Volume: 7, Issue:7

    Topics: Adolescent; Adult; China; Coinfection; Cross-Sectional Studies; Female; Hepatitis C; Hepatitis C Ant

2017
Spatial distribution of HIV, HCV, and co-infections among drug users in the southwestern border areas of China (2004-2014): a cohort study of a national methadone maintenance treatment program.
    BMC public health, 2017, 09-30, Volume: 17, Issue:1

    Topics: Adult; China; Cohort Studies; Coinfection; Drug Users; Female; Hepatitis C; HIV Infections; Humans;

2017
[TB/HIV co-infection associated with Kaposi's sarcoma under opioid substitution treatment using methadone: about a case].
    The Pan African medical journal, 2017, Volume: 28

    Topics: AIDS-Related Opportunistic Infections; Coinfection; Female; Heroin Dependence; HIV Infections; Human

2017
Methadone treatment, severe food insecurity, and HIV-HCV co-infection: A propensity score matching analysis.
    Drug and alcohol dependence, 2018, 04-01, Volume: 185

    Topics: Adult; Analgesics, Opioid; Canada; Cohort Studies; Coinfection; Female; Food Supply; Hepatitis C; HI

2018
Prevalence of and risk factors for hepatitis C virus antibody among people who inject drugs in Cambodia: a national biological and behavioral survey.
    Harm reduction journal, 2019, 04-29, Volume: 16, Issue:1

    Topics: Adult; Age Factors; Analgesics, Opioid; Antiviral Agents; Cambodia; Coinfection; Ethnicity; Female;

2019
High prevalence of HIV, HCV and tuberculosis and associated risk behaviours among new entrants of methadone maintenance treatment clinics in Guangdong Province, China.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Adult; Analgesics, Opioid; China; Coinfection; Comorbidity; Female; Hepatitis C; HIV Infections; Hum

2013
Incidence of hepatitis C infection among prisoners by routine laboratory values during a 20-year period.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adult; Analgesics, Opioid; Coinfection; Follow-Up Studies; Hepacivirus; Hepatitis C; Hepatitis C Ant

2014
The geographic distribution patterns of HIV-, HCV- and co-infections among drug users in a national methadone maintenance treatment program in Southwest China.
    BMC infectious diseases, 2014, Mar-10, Volume: 14

    Topics: Adult; China; Coinfection; Drug Users; Female; Geography, Medical; Hepatitis C; HIV Infections; Huma

2014
Hepatitis C virus infection and pain sensitivity in patients on methadone or buprenorphine maintenance therapy for opioid use disorders.
    Drug and alcohol dependence, 2015, Aug-01, Volume: 153

    Topics: Adult; Buprenorphine; Case-Control Studies; Coinfection; Female; Hepatitis C; HIV Infections; Humans

2015
Simeprevir-induced severe withdrawal syndrome in an HIV/HCV coinfected patient on long-term maintenance methadone therapy.
    European journal of clinical pharmacology, 2015, Volume: 71, Issue:8

    Topics: Antiretroviral Therapy, Highly Active; Antiviral Agents; Coinfection; Drug Interactions; Hepatitis C

2015
[Prevalence of HIV and HCV infections in patients receiving methadone maintenance treatment in Kaiyuan, Yunnan].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2015, Volume: 36, Issue:8

    Topics: China; Coinfection; Drug Users; Hepatitis C; HIV Infections; Humans; Methadone; Opiate Substitution

2015
Hepatitis C in a Mobile Low-Threshold Methadone Program.
    European journal of gastroenterology & hepatology, 2017, Volume: 29, Issue:6

    Topics: Adult; Aged; Alcohol-Related Disorders; Coinfection; Comorbidity; Cross-Sectional Studies; Drug User

2017
Prevalences and associated risk factors of HCV/HIV co-infection and HCV mono-infection among injecting drug users in a methadone maintenance treatment program in Taipei, Taiwan.
    BMC public health, 2012, Dec-11, Volume: 12

    Topics: Adult; Coinfection; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Hepatitis C;

2012