Page last updated: 2024-10-30

methadone and Cerebellar Diseases

methadone has been researched along with Cerebellar Diseases in 5 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Cerebellar Diseases: Diseases that affect the structure or function of the cerebellum. Cardinal manifestations of cerebellar dysfunction include dysmetria, GAIT ATAXIA, and MUSCLE HYPOTONIA.

Research Excerpts

ExcerptRelevanceReference
"Methadone-induced toxic encephalopathy is an extremely rare form of toxic encephalopathy which typically demonstrates abnormal imaging findings in the dentate nuclei or cerebellum."1.51Methadone-induced Toxic Encephalopathy In Pediatric Patients: Two Case Reports. ( Chieng, JSL; Khoo, HW; Ng, CH; Tiong, SC, 2019)
"These findings represent a toxic encephalopathy and have been reported in previous cases of heroin intoxication by inhalation, but rarely following opioid ingestion."1.35Severe cerebellitis following methadone poisoning. ( Devile, CJ; MacLennan, SC; Mills, F; Saunders, DE, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tiong, SC1
Chieng, JSL1
Khoo, HW1
Ng, CH1
Rando, J1
Szari, S1
Kumar, G1
Lingadevaru, H1
Razmkon, A1
Bakhtazad, A1
Marvel, CL1
Faulkner, ML1
Strain, EC1
Mintzer, MZ1
Desmond, JE1
Mills, F1
MacLennan, SC1
Devile, CJ1
Saunders, DE1

Other Studies

5 other studies available for methadone and Cerebellar Diseases

ArticleYear
Methadone-induced Toxic Encephalopathy In Pediatric Patients: Two Case Reports.
    Journal of radiology case reports, 2019, Volume: 13, Issue:5

    Topics: Analgesics, Opioid; Cerebellar Diseases; Child, Preschool; Diffusion Magnetic Resonance Imaging; Enc

2019
Methadone overdose causing acute cerebellitis and multi-organ damage.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:2

    Topics: Adolescent; Cerebellar Diseases; Drug Overdose; Humans; Magnetic Resonance Imaging; Male; Methadone;

2016
Possible mechanisms of rapid neurological deterioration and acute hydrocephalus in drug abusers.
    Pediatric radiology, 2009, Volume: 39, Issue:3

    Topics: Cerebellar Diseases; Child, Preschool; Diagnosis, Differential; Female; Humans; Magnetic Resonance I

2009
An fMRI investigation of cerebellar function during verbal working memory in methadone maintenance patients.
    Cerebellum (London, England), 2012, Volume: 11, Issue:1

    Topics: Adult; Cerebellar Diseases; Cerebellum; Female; Humans; Magnetic Resonance Imaging; Male; Memory Dis

2012
Severe cerebellitis following methadone poisoning.
    Pediatric radiology, 2008, Volume: 38, Issue:2

    Topics: Cerebellar Diseases; Child, Preschool; Diagnosis, Differential; Female; Humans; Magnetic Resonance I

2008