methadone has been researched along with Carcinoma, Ovarian Epithelial in 1 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Carcinoma, Ovarian Epithelial: A malignant neoplasm that originates in cells on the surface EPITHELIUM of the ovary and is the most common form of ovarian cancer. There are five histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Mutations in BRCA1, OPCML, PRKN, PIK3CA, AKT1, CTNNB1, RRAS2, and CDH1 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Its effects in ovarian cancer (OC) are completely unexplored." | 1.72 | Dubious effects of methadone as an "anticancer" drug on ovarian cancer cell-lines and patient-derived tumor-spheroids. ( Ausserlechner, MJ; Carpén, O; Fiegl, H; Hagenbuchner, J; Huhtinen, K; Kyvelidou, C; Marth, C; Parson, W; Reiser, E; Roessler, J; Seeber, B; Sopper, S; Sprung, S; Tsibulak, I; Wieser, V; Zeimet, AG, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fiegl, H | 1 |
| Hagenbuchner, J | 1 |
| Kyvelidou, C | 1 |
| Seeber, B | 1 |
| Sopper, S | 1 |
| Tsibulak, I | 1 |
| Wieser, V | 1 |
| Reiser, E | 1 |
| Roessler, J | 1 |
| Huhtinen, K | 1 |
| Carpén, O | 1 |
| Parson, W | 1 |
| Sprung, S | 1 |
| Marth, C | 1 |
| Ausserlechner, MJ | 1 |
| Zeimet, AG | 1 |
1 other study available for methadone and Carcinoma, Ovarian Epithelial
| Article | Year |
|---|---|
Dubious effects of methadone as an "anticancer" drug on ovarian cancer cell-lines and patient-derived tumor-spheroids.
Topics: Antineoplastic Agents; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cisplatin; Female; Humans; M | 2022 |