methadone has been researched along with Canine Diseases in 18 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether the administration of intravenous (IV) lidocaine before the induction of anaesthesia in premedicated dogs reduces the cough response associated with endotracheal intubation and the propofol dose required." | 9.22 | Effect of intravenous lidocaine on cough response to endotracheal intubation in propofol-anaesthetized dogs. ( Cafrita, IC; Clark, L; Panti, A, 2016) |
| "In healthy dogs premedicated with dexmedetomidine and methadone and maintained under GA with isoflurane and a femoral and sciatic nerve block, there was no relationship between the specific gravity of urine collected after premedication and intraoperative arterial hypotension." | 8.31 | Evaluation of urine specific gravity as a predictor of hypotension during anaesthesia in healthy dogs premedicated with dexmedetomidine. ( Le Chevallier, D; MacFarlane, PD; van Oostrom, H, 2023) |
| "To investigate the frequency of seizures associated with acepromazine administration when used as a premedicant with methadone for dogs undergoing myelography." | 7.78 | Incidence of seizures associated with the use of acepromazine in dogs undergoing myelography. ( Drynan, EA; Gray, P; Raisis, AL, 2012) |
| "To determine whether the administration of intravenous (IV) lidocaine before the induction of anaesthesia in premedicated dogs reduces the cough response associated with endotracheal intubation and the propofol dose required." | 5.22 | Effect of intravenous lidocaine on cough response to endotracheal intubation in propofol-anaesthetized dogs. ( Cafrita, IC; Clark, L; Panti, A, 2016) |
| "To compare the effects of morphine (MOR), methadone (MET), butorphanol (BUT) and tramadol (TRA), in combination with acepromazine, on sedation, cardiorespiratory variables, body temperature and incidence of emesis in dogs." | 5.14 | Comparative study on the sedative effects of morphine, methadone, butorphanol or tramadol, in combination with acepromazine, in dogs. ( Assis, HM; Campagnol, D; Junior, AR; Monteiro, ER; Quitzan, JG, 2009) |
| "In healthy dogs premedicated with dexmedetomidine and methadone and maintained under GA with isoflurane and a femoral and sciatic nerve block, there was no relationship between the specific gravity of urine collected after premedication and intraoperative arterial hypotension." | 4.31 | Evaluation of urine specific gravity as a predictor of hypotension during anaesthesia in healthy dogs premedicated with dexmedetomidine. ( Le Chevallier, D; MacFarlane, PD; van Oostrom, H, 2023) |
| "To investigate the frequency of seizures associated with acepromazine administration when used as a premedicant with methadone for dogs undergoing myelography." | 3.78 | Incidence of seizures associated with the use of acepromazine in dogs undergoing myelography. ( Drynan, EA; Gray, P; Raisis, AL, 2012) |
| "To evaluate the efficacy of a perineural injection of dexmedetomidine combined with ropivacaine for reducing postoperative methadone requirements in dogs after tibial plateau levelling osteotomy (TPLO)." | 3.11 | Effects of perineural dexmedetomidine combined with ropivacaine on postoperative methadone requirements in dogs after tibial plateau levelling osteotomy: a two-centre study. ( Marolf, V; Picavet, P; Sandersen, C; Selz, J; Spadavecchia, C; Tutunaru, A, 2022) |
| "To assess the pharmacokinetics, clinical efficacy, and adverse effects of injectable methadone with the pharmacokinetic enhancer fluconazole (methadone-fluconazole), compared with the standard formulation of injectable methadone, in dogs after ovariohysterectomy." | 3.11 | Long-acting injectable methadone (methadone-fluconazole) provides safe and effective postoperative analgesia in a randomized clinical trial for dogs undergoing soft tissue surgery. ( Berke, KA; Bieberly, ZD; Comroe, AJ; Fitzgerald, AH; Jugan, MC; Klocke, EE; Klutzke, JB; KuKanich, B; KuKanich, KS; Mason, DE; Orchard, RJ; Upchurch, DA; Woodruff, K, 2022) |
| " Blood samples were collected for pharmacokinetic analysis, and rectal temperature and sedation were assessed to evaluate opioid effects at predetermined times up to 24 hours after treatment." | 2.94 | Pharmacokinetics and pharmacodynamics of a novel analgesic with a deterrent to human opioid abuse (methadone-fluconazole-naltrexone) after oral administration in dogs. ( Joo, H; KuKanich, B; KuKanich, K; Locuson, CW; Rankin, DC, 2020) |
| "To assess the pharmacokinetics and opioid effects of methadone after administration of multiple doses by means of 2 dosing regimens of methadone-fluconazole-naltrexone." | 1.62 | Multiple-dose pharmacokinetics and opioid effects of a novel analgesic with a deterrent to human opioid abuse (methadone-fluconazole-naltrexone) after oral administration in dogs. ( Cho, P; Fitzgerald, AH; Komp, MS; KuKanich, B; KuKanich, K; Locuson, CW; Rankin, DC, 2021) |
| "Where hypotension was present, the method of and response to treatment was recorded." | 1.36 | A comparison of anesthetic complications between diabetic and nondiabetic dogs undergoing phacoemulsification cataract surgery: a retrospective study. ( Clark, L; Corletto, F; Gould, DJ; Oliver, JA, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 9 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marolf, V | 1 |
| Selz, J | 1 |
| Picavet, P | 1 |
| Spadavecchia, C | 2 |
| Tutunaru, A | 1 |
| Sandersen, C | 1 |
| Bieberly, ZD | 1 |
| KuKanich, B | 4 |
| KuKanich, KS | 1 |
| Berke, KA | 1 |
| Klocke, EE | 2 |
| Upchurch, DA | 2 |
| Comroe, AJ | 1 |
| Jugan, MC | 1 |
| Mason, DE | 1 |
| Orchard, RJ | 1 |
| Klutzke, JB | 1 |
| Fitzgerald, AH | 3 |
| Woodruff, K | 1 |
| Ryan, AC | 1 |
| Murrell, JC | 1 |
| Gurney, MA | 1 |
| Viilmann, I | 2 |
| Drozdzynska, M | 2 |
| Vettorato, E | 2 |
| Le Chevallier, D | 1 |
| van Oostrom, H | 1 |
| MacFarlane, PD | 1 |
| Kerr, CL | 1 |
| Swanton, WE | 1 |
| KuKanich, K | 3 |
| Rankin, DC | 3 |
| Locuson, CW | 2 |
| Joo, H | 1 |
| Comroe, A | 1 |
| Crauer, B | 1 |
| Berke, K | 1 |
| Gonzalez, SE | 1 |
| Mason, D | 1 |
| Jensen, G | 1 |
| Orchard, R | 1 |
| Cho, P | 2 |
| Komp, M | 1 |
| Komp, MS | 1 |
| Tanner, JC | 1 |
| Lake-Bakaar, GA | 1 |
| Kittleson, MD | 1 |
| Adami, C | 1 |
| Casoni, D | 1 |
| Panti, A | 1 |
| Cafrita, IC | 1 |
| Clark, L | 2 |
| Monteiro, ER | 1 |
| Junior, AR | 1 |
| Assis, HM | 1 |
| Campagnol, D | 1 |
| Quitzan, JG | 1 |
| Oliver, JA | 1 |
| Corletto, F | 1 |
| Gould, DJ | 1 |
| Van Vynckt, D | 2 |
| Samoy, Y | 2 |
| Polis, I | 2 |
| Bosmans, T | 2 |
| Verschooten, F | 1 |
| Van Ryssen, B | 1 |
| Drynan, EA | 1 |
| Gray, P | 1 |
| Raisis, AL | 1 |
| Piron, K | 1 |
| Oosterlinck, M | 1 |
| Gasthuys, F | 1 |
| Duchateau, L | 1 |
| Waelbers, T | 1 |
| Biewenga, WJ | 1 |
| van Oosterom, RA | 1 |
1 review available for methadone and Canine Diseases
| Article | Year |
|---|---|
Anesthesia update - Incorporating methadone into companion animal anesthesia and analgesic protocols: A narrative review.
Topics: Analgesics, Opioid; Anesthesia; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Methadone; Pain; Pe | 2023 |
6 trials available for methadone and Canine Diseases
| Article | Year |
|---|---|
Effects of perineural dexmedetomidine combined with ropivacaine on postoperative methadone requirements in dogs after tibial plateau levelling osteotomy: a two-centre study.
Topics: Anesthetics, Local; Animals; Dexmedetomidine; Dog Diseases; Dogs; Hospitals, Animal; Hospitals, Teac | 2022 |
Long-acting injectable methadone (methadone-fluconazole) provides safe and effective postoperative analgesia in a randomized clinical trial for dogs undergoing soft tissue surgery.
Topics: Analgesia; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Female; Fluconazole; Hysterectomy; Metha | 2022 |
Pharmacokinetics and pharmacodynamics of a novel analgesic with a deterrent to human opioid abuse (methadone-fluconazole-naltrexone) after oral administration in dogs.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Fluconazole; Methadone; Naltr | 2020 |
Effect of intravenous lidocaine on cough response to endotracheal intubation in propofol-anaesthetized dogs.
Topics: Acepromazine; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Animals; Arterial Pr | 2016 |
Comparative study on the sedative effects of morphine, methadone, butorphanol or tramadol, in combination with acepromazine, in dogs.
Topics: Acepromazine; Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Body T | 2009 |
Comparison of analgesic efficacy of epidural methadone or ropivacaine/methadone with or without pre-operative oral tepoxalin in dogs undergoing tuberositas tibiae advancement surgery.
Topics: Administration, Oral; Amides; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Age | 2012 |
11 other studies available for methadone and Canine Diseases
| Article | Year |
|---|---|
Post-operative nausea and vomiting (PONV) observed in a clinical study designed to assess the analgesic effects of intravenous and subcutaneous methadone in dogs.
Topics: Analgesia; Analgesics, Opioid; Animals; Bupivacaine; Dog Diseases; Dogs; Methadone; Pain, Postoperat | 2022 |
Analgesic efficacy of a bilateral erector spinae plane block versus a fentanyl constant rate infusion in dogs undergoing hemilaminectomy: a retrospective cohort study.
Topics: Analgesics; Anesthetics; Animals; Dog Diseases; Dogs; Fentanyl; Methadone; Nerve Block; Pain, Postop | 2022 |
Analgesic efficacy of a bilateral erector spinae plane block versus a fentanyl constant rate infusion in dogs undergoing hemilaminectomy: a retrospective cohort study.
Topics: Analgesics; Anesthetics; Animals; Dog Diseases; Dogs; Fentanyl; Methadone; Nerve Block; Pain, Postop | 2022 |
Analgesic efficacy of a bilateral erector spinae plane block versus a fentanyl constant rate infusion in dogs undergoing hemilaminectomy: a retrospective cohort study.
Topics: Analgesics; Anesthetics; Animals; Dog Diseases; Dogs; Fentanyl; Methadone; Nerve Block; Pain, Postop | 2022 |
Analgesic efficacy of a bilateral erector spinae plane block versus a fentanyl constant rate infusion in dogs undergoing hemilaminectomy: a retrospective cohort study.
Topics: Analgesics; Anesthetics; Animals; Dog Diseases; Dogs; Fentanyl; Methadone; Nerve Block; Pain, Postop | 2022 |
Evaluation of urine specific gravity as a predictor of hypotension during anaesthesia in healthy dogs premedicated with dexmedetomidine.
Topics: Anesthesia, General; Animals; Cohort Studies; Dexmedetomidine; Dog Diseases; Dogs; Hypotension; Isof | 2023 |
Perioperative analgesia associated with oral administration of a novel methadone-fluconazole-naltrexone formulation in dogs undergoing routine ovariohysterectomy.
Topics: Administration, Oral; Analgesia; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Female; Fluconazol | 2020 |
Multiple-dose pharmacokinetics and opioid effects of a novel analgesic with a deterrent to human opioid abuse (methadone-fluconazole-naltrexone) after oral administration in dogs.
Topics: Administration, Oral; Analgesics; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Fluconazole; Huma | 2021 |
ECG of the Month. Arrhythmia.
Topics: Animals; Arrhythmias, Cardiac; Atropine; Dog Diseases; Dogs; Electrocardiography; Ethylene Glycol; F | 2013 |
Seizure activity occurring in two dogs after S-ketamine-induction.
Topics: Acepromazine; Analgesics, Opioid; Anesthesia, General; Anesthetics, Dissociative; Animals; Anticonvu | 2013 |
A comparison of anesthetic complications between diabetic and nondiabetic dogs undergoing phacoemulsification cataract surgery: a retrospective study.
Topics: Acepromazine; Anesthesia, Intravenous; Animals; Bradycardia; Cataract; Diabetes Mellitus; Dog Diseas | 2010 |
Evaluation of two sedation protocols for use before diagnostic intra-articular anaesthesia in lame dogs.
Topics: Acepromazine; Anesthesia; Animals; Conscious Sedation; Dog Diseases; Dogs; Female; Hypnotics and Sed | 2011 |
Incidence of seizures associated with the use of acepromazine in dogs undergoing myelography.
Topics: Acepromazine; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Dopamine Antagonists; Female; Male; M | 2012 |
Cystourethroscopy in the dog.
Topics: Animals; Cystoscopes; Cystoscopy; Dog Diseases; Dogs; Droperidol; Female; Male; Methadone; Urethra; | 1985 |