methadone has been researched along with Cancer of Pituitary in 2 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methadone (Mtd) is a widely used opioid drug associated with the side effect of hyperprolactinemia." | 1.37 | Inhibitory action of methadone and its metabolites on erg-mediated K+ current in GH₃ pituitary tumor cells. ( Chen, BS; Chen, CT; Hsu, TI; Huang, MH; Kang, YF; Shen, AY; Wang, TS; Wu, HM; Wu, SN, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, MH | 1 |
| Shen, AY | 1 |
| Wang, TS | 1 |
| Wu, HM | 1 |
| Kang, YF | 1 |
| Chen, CT | 1 |
| Hsu, TI | 1 |
| Chen, BS | 1 |
| Wu, SN | 1 |
| Borgland, SL | 1 |
| Connor, M | 1 |
| Osborne, PB | 1 |
| Furness, JB | 1 |
| Christie, MJ | 1 |
2 other studies available for methadone and Cancer of Pituitary
| Article | Year |
|---|---|
Inhibitory action of methadone and its metabolites on erg-mediated K+ current in GH₃ pituitary tumor cells.
Topics: Animals; Cell Line, Tumor; Ether-A-Go-Go Potassium Channels; Methadone; Naloxone; Narcotics; Neurons | 2011 |
Opioid agonists have different efficacy profiles for G protein activation, rapid desensitization, and endocytosis of mu-opioid receptors.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Electric Conductivity; Endocytosis; Enkephalin, | 2003 |