methadone and Brain Vascular Disorders studies

methadone and Brain Vascular Disorders

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Research Excerpts

Excerpt	Relevance	Reference
"Methadone overdose can cause DAL with profound disturbances of neural metabolism and the BBB."	1.39	Imaging of subacute blood-brain barrier disruption after methadone overdose. ( Gasparovic, C; Huisa, BN; Prestopnik, JL; Rosenberg, GA; Taheri, S, 2013)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	1 (33.33)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

1 (33.33)

18.2507

2000's

1 (33.33)

29.6817

2010's

1 (33.33)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Huisa, BN	1
Gasparovic, C	1
Taheri, S	1
Prestopnik, JL	1
Rosenberg, GA	1
Herning, RI	1
Better, WE	1
Tate, K	1
Umbricht, A	1
Preston, KL	1
Cadet, JL	1
Zylicz, Z	1

Studies

Huisa, BN

Gasparovic, C

Taheri, S

Prestopnik, JL

Rosenberg, GA

Herning, RI

Better, WE

Tate, K

Umbricht, A

Preston, KL

Cadet, JL

Zylicz, Z

Other Studies

3 other studies available for methadone and Brain Vascular Disorders

Article	Year
Imaging of subacute blood-brain barrier disruption after methadone overdose. Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2013, Volume: 23, Issue:3 Topics: Adult; Blood-Brain Barrier; Cerebrovascular Disorders; Drug Overdose; Humans; Magnetic Resonance Ang	2013
Methadone treatment induces attenuation of cerebrovascular deficits associated with the prolonged abuse of cocaine and heroin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3 Topics: Adult; Analysis of Variance; Anterior Cerebral Artery; Cerebrovascular Circulation; Cerebrovascular	2003
Opioid responsive central pain of cerebrovascular origin: a case report. Palliative medicine, 1997, Volume: 11, Issue:6 Topics: Analgesics, Opioid; Cerebrovascular Disorders; Humans; Male; Methadone; Middle Aged; Morphine; Pain,	1997

Article

Year

Imaging of subacute blood-brain barrier disruption after methadone overdose.

Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2013, Volume: 23, Issue:3

Topics: Adult; Blood-Brain Barrier; Cerebrovascular Disorders; Drug Overdose; Humans; Magnetic Resonance Ang

2013

Methadone treatment induces attenuation of cerebrovascular deficits associated with the prolonged abuse of cocaine and heroin.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3

Topics: Adult; Analysis of Variance; Anterior Cerebral Artery; Cerebrovascular Circulation; Cerebrovascular

2003

Opioid responsive central pain of cerebrovascular origin: a case report.

Palliative medicine, 1997, Volume: 11, Issue:6

Topics: Analgesics, Opioid; Cerebrovascular Disorders; Humans; Male; Methadone; Middle Aged; Morphine; Pain,

1997