methadone has been researched along with Brain Edema in 3 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Excerpt | Relevance | Reference |
---|---|---|
"Here, we report a patient who developed acute bilateral hearing loss, ataxia and paraparesis subsequently to intravenous methadone-abuse." | 4.02 | Intravenous methadone causes acute toxic and delayed inflammatory encephalopathy with persistent neurocognitive impairments. ( Haessner, S; Johnen, A; Landmeyer, NC; Meyer Zu Hörste, G; Pawlitzki, M; Repple, J; Schulte-Mecklenbeck, A; Wiendl, H, 2021) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 1 (33.33) | 2.80 |
Authors | Studies |
---|---|
Repple, J | 1 |
Haessner, S | 1 |
Johnen, A | 1 |
Landmeyer, NC | 1 |
Schulte-Mecklenbeck, A | 1 |
Pawlitzki, M | 1 |
Wiendl, H | 1 |
Meyer Zu Hörste, G | 1 |
Winklhofer, S | 1 |
Surer, E | 1 |
Ampanozi, G | 1 |
Ruder, T | 1 |
Stolzmann, P | 1 |
Elliott, M | 1 |
Oestreich, A | 1 |
Kraemer, T | 1 |
Thali, M | 1 |
Alkadhi, H | 1 |
Schweitzer, W | 1 |
Carson, HJ | 1 |
Feickert, BL | 1 |
3 other studies available for methadone and Brain Edema
Article | Year |
---|---|
Intravenous methadone causes acute toxic and delayed inflammatory encephalopathy with persistent neurocognitive impairments.
Topics: Administration, Intravenous; Analgesics, Opioid; Ataxia; Brain; Brain Diseases; Brain Edema; Cogniti | 2021 |
Post-mortem whole body computed tomography of opioid (heroin and methadone) fatalities: frequent findings and comparison to autopsy.
Topics: Adolescent; Adult; Autopsy; Brain Edema; Cardiomegaly; Cause of Death; Female; Forensic Pathology; H | 2014 |
Identification at autopsy of pulverized pills in lungs of a first-time methadone user.
Topics: Administration, Inhalation; Adult; Brain Edema; Dronabinol; Drug Interactions; Drug Users; Fatal Out | 2009 |