methadone has been researched along with Brain Diseases in 7 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here, we report a patient who developed acute bilateral hearing loss, ataxia and paraparesis subsequently to intravenous methadone-abuse." | 4.02 | Intravenous methadone causes acute toxic and delayed inflammatory encephalopathy with persistent neurocognitive impairments. ( Haessner, S; Johnen, A; Landmeyer, NC; Meyer Zu Hörste, G; Pawlitzki, M; Repple, J; Schulte-Mecklenbeck, A; Wiendl, H, 2021) |
| "Methadone intoxication was confirmed based on history, congruent clinical presentation, and confirmatory urine analysis." | 2.66 | Methadone-induced encephalopathy: a case series and literature review. ( Ahmad-Molaei, L; Haghighi-Morad, M; Hassanian-Moghaddam, H; Jamshidi, N; Naseri, Z; Zamani, N, 2020) |
| " Recommendations are made for further research into physician/patient interactions and into optimal dosing of methadone and buprenorphine to minimize maternal/fetal withdrawal." | 2.55 | Opioid dependence and pregnancy: minimizing stress on the fetal brain. ( Fassbender, C; Finnegan, LP; Leamon, MH; McCarthy, JJ, 2017) |
| " Nocturnal sleep was not markedly altered during the chronic administration of methadone." | 1.25 | Human sleep and EEG through a cycle of methadone dependence. ( Kay, DC, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Haghighi-Morad, M | 1 |
| Naseri, Z | 1 |
| Jamshidi, N | 1 |
| Hassanian-Moghaddam, H | 1 |
| Zamani, N | 1 |
| Ahmad-Molaei, L | 1 |
| Repple, J | 1 |
| Haessner, S | 1 |
| Johnen, A | 1 |
| Landmeyer, NC | 1 |
| Schulte-Mecklenbeck, A | 1 |
| Pawlitzki, M | 1 |
| Wiendl, H | 1 |
| Meyer Zu Hörste, G | 1 |
| McCarthy, JJ | 1 |
| Leamon, MH | 1 |
| Finnegan, LP | 1 |
| Fassbender, C | 1 |
| Anselmo, M | 1 |
| Campos Rainho, A | 1 |
| do Carmo Vale, M | 1 |
| Estrada, J | 1 |
| Valente, R | 1 |
| Correia, M | 1 |
| Vieira, JP | 1 |
| Barata, D | 1 |
| Handelsman, L | 1 |
| Song, IS | 1 |
| Losonczy, M | 1 |
| Park, S | 1 |
| Jacobson, J | 1 |
| Wiener, J | 1 |
| Aronson, M | 1 |
| Bleich, A | 1 |
| Adelson, M | 1 |
| Kay, DC | 1 |
3 reviews available for methadone and Brain Diseases
| Article | Year |
|---|---|
Methadone-induced encephalopathy: a case series and literature review.
Topics: Adolescent; Adult; Brain Diseases; Child; Child, Preschool; Diffusion Magnetic Resonance Imaging; Di | 2020 |
Opioid dependence and pregnancy: minimizing stress on the fetal brain.
Topics: Brain Diseases; Buprenorphine; Female; Fetal Diseases; Humans; Methadone; Opioid-Related Disorders; | 2017 |
[Opiate addiction as a chronic brain disease: new concept of an old problem, and re-evaluation of methadone treatment].
Topics: Brain Diseases; Chronic Disease; Humans; Methadone; Narcotics; Opioid-Related Disorders | 2000 |
4 other studies available for methadone and Brain Diseases
| Article | Year |
|---|---|
Intravenous methadone causes acute toxic and delayed inflammatory encephalopathy with persistent neurocognitive impairments.
Topics: Administration, Intravenous; Analgesics, Opioid; Ataxia; Brain; Brain Diseases; Brain Edema; Cogniti | 2021 |
Methadone intoxication in a child: toxic encephalopathy?
Topics: Analgesics, Opioid; Brain Diseases; Child, Preschool; Humans; Male; Methadone; Neurotoxicity Syndrom | 2006 |
Magnetic resonance abnormalities in HIV infection: a study in the drug-user risk group.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; Brain; Brain Diseases; Cognition D | 1993 |
Human sleep and EEG through a cycle of methadone dependence.
Topics: Adult; Brain Diseases; Dreams; Electroencephalography; Fourier Analysis; Heroin Dependence; Humans; | 1975 |