methadone has been researched along with Bipolar Disorder in 15 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonidine's actions and efficacy in mental disorders are reviewed and examined." | 5.06 | Psychiatric indications for clonidine: the neuropharmacologic and clinical basis. ( Bond, WS, 1986) |
| " Given the scarcity of data on the effects of lithium and methadone treatment, the aim of this clinical case report is to explain the interactions produced between methadone and lithium carbonate, in a female patient with medical multi-pathology, opioid-dependent and with comorbid bipolar disorder, who was treated with both drugs." | 3.75 | [Concomitant lithium and methadone treatment in a bipolar patient: a case report]. ( Barral, C; Casas, M; López-Ortiz, C; Roncero, C; Rovira, M; Sáez-Francàs, N, 2009) |
| " Bipolar 1 patients needed a higher methadone dosage in the stabilization phase, but this difference was not statistically significant." | 1.39 | The long-term outcomes of heroin dependent-treatment-resistant patients with bipolar 1 comorbidity after admission to enhanced methadone maintenance. ( Akiskal, H; Bacciardi, S; Maremmani, AGI; Maremmani, I; Osso, LD; Pacini, M; Paolo Pani, P; Rovai, L; Rugani, F, 2013) |
| "Recent clinical studies suggest that substance use may be associated with an acceleration of the ageing process, possibly related to a deficit of stem cell number or function." | 1.35 | An intriguing association between dental and mental pathology in addicted and control subjects: a cross-sectional survey. ( Reece, AS, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (46.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Andrade, G | 1 |
| Simões do Couto, F | 1 |
| Câmara-Pestana, L | 1 |
| Maremmani, AGI | 1 |
| Rovai, L | 1 |
| Bacciardi, S | 1 |
| Rugani, F | 1 |
| Pacini, M | 3 |
| Paolo Pani, P | 1 |
| Osso, LD | 1 |
| Akiskal, H | 2 |
| Maremmani, I | 3 |
| Reece, AS | 1 |
| Popovic, D | 1 |
| Romano, A | 1 |
| Maremmani, AG | 1 |
| Perugi, G | 2 |
| Deltito, J | 1 |
| Akiskal, K | 1 |
| Roncero, C | 1 |
| López-Ortiz, C | 1 |
| Barral, C | 1 |
| Sáez-Francàs, N | 1 |
| Rovira, M | 1 |
| Casas, M | 1 |
| Akiskal, HS | 1 |
| Judd, LL | 2 |
| Risch, SC | 2 |
| Segal, DS | 2 |
| Janowsky, DS | 2 |
| Huey, LY | 2 |
| Parker, DC | 1 |
| Kolar, AF | 1 |
| Brown, BS | 1 |
| Haertzen, CA | 1 |
| Michaelson, BS | 1 |
| Rosenblum, A | 1 |
| Fallon, B | 1 |
| Magura, S | 1 |
| Handelsman, L | 1 |
| Foote, J | 1 |
| Bernstein, D | 1 |
| Post, RM | 2 |
| Cramer, H | 1 |
| Goodwin, FK | 2 |
| Gold, MS | 1 |
| Byck, R | 1 |
| Bond, WS | 1 |
| Dunner, DL | 1 |
| Gordon, EK | 1 |
| McKenna, GJ | 1 |
| Fisch, A | 1 |
| Levine, ME | 1 |
| Patch, VD | 1 |
| Raynes, AE | 1 |
3 reviews available for methadone and Bipolar Disorder
| Article | Year |
|---|---|
[Recommendations about the Use of Psychotropic Medications during the COVID-19 Pandemic].
Topics: Antiviral Agents; Benzodiazepines; Betacoronavirus; Bipolar Disorder; Body Temperature Regulation; B | 2020 |
Toward a unitary perspective on the bipolar spectrum and substance abuse: opiate addiction as a paradigm.
Topics: Alcoholism; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cocaine-Related Disorders; Comorbid | 2006 |
Behavioral and neuroendocrine effects of opioid receptor agonists in psychopathologic states.
Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Depressive Disorder; Endorphins; Humans; Hy | 1983 |
3 trials available for methadone and Bipolar Disorder
| Article | Year |
|---|---|
The effect of methadone on the behavioral and neuroendocrine responses of manic patients.
Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Clonidine; Growth Hormone; Humans; Hydrocor | 1982 |
The autonomy of mood disorders among cocaine-using methadone patients.
Topics: Adult; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Comorb | 1999 |
Psychiatric indications for clonidine: the neuropharmacologic and clinical basis.
Topics: Animals; Anxiety; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug T | 1986 |
9 other studies available for methadone and Bipolar Disorder
| Article | Year |
|---|---|
The long-term outcomes of heroin dependent-treatment-resistant patients with bipolar 1 comorbidity after admission to enhanced methadone maintenance.
Topics: Adult; Bipolar Disorder; Diagnosis, Dual (Psychiatry); Female; Heroin; Heroin Dependence; Humans; Ma | 2013 |
An intriguing association between dental and mental pathology in addicted and control subjects: a cross-sectional survey.
Topics: Adolescent; Adult; Aggression; Aging; Alcohol Drinking; Amphetamine-Related Disorders; Anxiety; Atte | 2008 |
Affective temperaments in heroin addiction.
Topics: Adult; Alcoholism; Anxiety Disorders; Bipolar Disorder; Cohort Studies; Comorbidity; Cyclothymic Dis | 2009 |
[Concomitant lithium and methadone treatment in a bipolar patient: a case report].
Topics: Antimanic Agents; Bipolar Disorder; Drug Interactions; Drug Therapy, Combination; Female; Humans; Li | 2009 |
Children of substance abusers: the life experiences of children of opiate addicts in methadone maintenance.
Topics: Adolescent; Adult; Antisocial Personality Disorder; Bipolar Disorder; Child; Child Abuse; Child Abus | 1994 |
Cyclic AMP in cerebrospinal fluid of manic and depressive patients.
Topics: Administration, Oral; Amitriptyline; Bipolar Disorder; Cyclic AMP; Depression; Humans; Imipramine; L | 1977 |
Endorphins, lithium, and naloxone: their relationship to pathological and drug-induced manic-euphoric states.
Topics: Adult; Amphetamine; Bipolar Disorder; Cocaine; Dopamine; Endorphins; Euphoria; Heroin Dependence; Hu | 1978 |
Cerebrospinal fluid amine metabolites in affective illness: the probenecid technique.
Topics: Affective Symptoms; Biological Transport, Active; Bipolar Disorder; Brain; Brain Chemistry; Depressi | 1973 |
The use of methadone as a psychotropic agent.
Topics: Adult; Association; Bipolar Disorder; Boston; Follow-Up Studies; Heroin Dependence; Humans; Interper | 1973 |