methadone has been researched along with Asystole in 11 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the relative frequency of reporting of adverse events involving ventricular arrhythmia, cardiac arrest, corrected QT interval (QTc) prolongation or torsade de pointes to the US Food and Drug Administration (FDA) between buprenorphine and methadone." | 7.81 | Arrhythmia associated with buprenorphine and methadone reported to the Food and Drug Administration. ( Haigney, MC; Kao, DP; Krantz, MJ; Mehler, PS, 2015) |
| "To assess the relative frequency of reporting of adverse events involving ventricular arrhythmia, cardiac arrest, corrected QT interval (QTc) prolongation or torsade de pointes to the US Food and Drug Administration (FDA) between buprenorphine and methadone." | 3.81 | Arrhythmia associated with buprenorphine and methadone reported to the Food and Drug Administration. ( Haigney, MC; Kao, DP; Krantz, MJ; Mehler, PS, 2015) |
| "1646 cases of ventricular arrhythmia or cardiac arrest and 379 cases of QTc prolongation or torsade de pointes were associated with methadone." | 3.79 | Trends in reporting methadone-associated cardiac arrhythmia, 1997-2011: an analysis of registry data. ( Bucher Bartelson, B; Dart, R; Kao, D; Katz, D; Khatri, V; Krantz, MJ; Mehler, PS, 2013) |
| "In this study, a case of sudden cardiac arrest in a patient on chronic methadone therapy is presented." | 1.39 | Sudden cardiac arrest in a patient on chronic methadone after the addition of azithromycin. ( Twilla, JD; Winton, JC, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kao, D | 1 |
| Bucher Bartelson, B | 1 |
| Khatri, V | 1 |
| Dart, R | 1 |
| Mehler, PS | 3 |
| Katz, D | 1 |
| Krantz, MJ | 3 |
| Kao, DP | 1 |
| Haigney, MC | 1 |
| Walton, G | 1 |
| Nolan, S | 1 |
| Sutherland, C | 1 |
| Ahamad, K | 1 |
| Behr, ER | 1 |
| Camm, AJ | 1 |
| Palmiere, C | 1 |
| Brunel, C | 1 |
| Sporkert, F | 1 |
| Augsburger, M | 1 |
| Winton, JC | 1 |
| Twilla, JD | 1 |
| Rowan, SB | 1 |
| Martins, HS | 1 |
| Silva, RV | 1 |
| Bugano, D | 1 |
| Santana, AN | 1 |
| Brandão-Neto, RA | 1 |
| Giannini, FP | 1 |
| Scalabrini-Neto, A | 1 |
| Velasco, IT | 1 |
| Junttila, MJ | 1 |
| Gonzalez, M | 1 |
| Lizotte, E | 1 |
| Benito, B | 1 |
| Vernooy, K | 1 |
| Sarkozy, A | 1 |
| Huikuri, HV | 1 |
| Brugada, P | 1 |
| Brugada, J | 1 |
| Brugada, R | 1 |
| Lorenzo, JA | 1 |
| Weinstock, DJ | 1 |
| Kerr, F | 1 |
| Donald, KW | 1 |
3 reviews available for methadone and Asystole
| Article | Year |
|---|---|
Should naloxone be prescribed in the ED management of patients with cardiac arrest? A case report and review of literature.
Topics: Analgesics, Opioid; Emergency Service, Hospital; Female; Heart Arrest; Humans; Methadone; Middle Age | 2008 |
Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias.
Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death | 2008 |
Editorial: Analgesia in myocardial infarction.
Topics: Analgesia; Analgesics; Animals; Blood Pressure; Cyclizine; Heart Arrest; Heroin; Humans; Injections, | 1974 |
8 other studies available for methadone and Asystole
| Article | Year |
|---|---|
Trends in reporting methadone-associated cardiac arrhythmia, 1997-2011: an analysis of registry data.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Anti-Retroviral Agents; Heart Arrest; HIV Infections | 2013 |
Arrhythmia associated with buprenorphine and methadone reported to the Food and Drug Administration.
Topics: Adult; Arrhythmias, Cardiac; Buprenorphine; Female; Heart Arrest; Humans; Long QT Syndrome; Male; Me | 2015 |
Sustained release oral morphine as an alternative to methadone for the treatment of opioid-use disorder post Torsades de Pointes cardiac arrest.
Topics: Administration, Oral; Delayed-Action Preparations; Electrocardiography; Heart Arrest; Humans; Male; | 2015 |
Letter by Behr and Camm regarding article, "Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias".
Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death | 2008 |
An unusual case of accidental poisoning: fatal methadone inhalation.
Topics: Accidents; Administration, Inhalation; Adult; Forensic Toxicology; Heart Arrest; Humans; Male; Metha | 2011 |
Sudden cardiac arrest in a patient on chronic methadone after the addition of azithromycin.
Topics: Azithromycin; Death, Sudden, Cardiac; Drug Therapy, Combination; Heart Arrest; Humans; Male; Methado | 2013 |
Cocaine-related torsade de pointes in a methadone maintenance patient.
Topics: Cocaine; Dopamine Uptake Inhibitors; Drug Interactions; Female; Heart Arrest; Heroin Dependence; Hum | 2005 |
Pertinent medical intelligence: methadone ingestion in children.
Topics: Child, Preschool; Drug Overdose; Emergencies; Epilepsy, Generalized; Heart Arrest; Humans; Infant; M | 1995 |