methadone has been researched along with Apnea, Central in 7 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a child with acute myeloid leukemia (AML) who developed severe central sleep apnea (CSA) on methadone therapy for chronic pain management." | 3.79 | Severe central sleep apnea in a child with leukemia on chronic methadone therapy. ( Amos, LB; D'Andrea, LA, 2013) |
| "Our objectives were to: (1) characterize obstructive sleep apnea (OSA) and CSA in patients in methadone maintenance treatment (MMT) for opioid dependence; (2) examine factors associated with SDB in this population; and (3) investigate whether SDB was related to severity of subjective sleep complaints in MMT patients with subjective sleep disturbances." | 1.36 | Obstructive sleep apnea is more common than central sleep apnea in methadone maintenance patients with subjective sleep complaints. ( Anderson, BJ; Corso, RP; Kurth, ME; Millman, RP; Sharkey, KM; Stein, MD, 2010) |
| "Thirty percent of MMT patients had a central apnea index (CAI) > 5, and 20% had a CAI > 10." | 1.33 | Central sleep apnea in stable methadone maintenance treatment patients. ( Cherry, G; Cunnington, D; Drummer, O; Goodman, C; Kronborg, I; Teichtahl, H; Wang, D, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, D | 3 |
| Lintzeris, N | 1 |
| Leung, S | 1 |
| Haber, PS | 1 |
| Yee, BJ | 1 |
| Grunstein, RR | 2 |
| Teichtahl, H | 3 |
| Goodman, C | 2 |
| Drummer, O | 2 |
| Kronborg, I | 3 |
| Sharkey, KM | 1 |
| Kurth, ME | 1 |
| Anderson, BJ | 1 |
| Corso, RP | 1 |
| Millman, RP | 1 |
| Stein, MD | 1 |
| Amos, LB | 1 |
| D'Andrea, LA | 1 |
| Durst, P | 1 |
| Palazzolo, J | 1 |
| Peyrelong, JP | 1 |
| Berger, M | 1 |
| Chalabreysse, M | 1 |
| Billiard, M | 1 |
| Vialle, A | 1 |
| Cherry, G | 2 |
| Cunnington, D | 1 |
| Prodromidis, A | 1 |
| Miller, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Acute Intravenous Morphine Administration on Sleep Disordered Breathing (SDB) in Patients With Moderate Obstructive Sleep Apnoea (OSA): A Paired Design Trial[NCT03127800] | Phase 3 | 6 participants (Actual) | Interventional | 2016-05-20 | Terminated (stopped due to Difficulties with recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for methadone and Apnea, Central
| Article | Year |
|---|---|
Reversal of central sleep apnoea with change from methadone to buprenorphine-naloxone: a case report.
Topics: Buprenorphine, Naloxone Drug Combination; Heroin Dependence; Humans; Hypoxia; Male; Methadone; Middl | 2015 |
Subjective daytime sleepiness and daytime function in patients on stable methadone maintenance treatment: possible mechanisms.
Topics: Adult; Australia; Case-Control Studies; Depression; Female; Humans; Male; Methadone; Middle Aged; Na | 2008 |
Obstructive sleep apnea is more common than central sleep apnea in methadone maintenance patients with subjective sleep complaints.
Topics: Adult; Body Mass Index; Female; Humans; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Diso | 2010 |
Severe central sleep apnea in a child with leukemia on chronic methadone therapy.
Topics: Analgesics, Opioid; Child; Humans; Leukemia, Myeloid, Acute; Male; Methadone; Pain; Severity of Illn | 2013 |
[Methadone and sleep apnea syndrome].
Topics: Adult; Brain; Clonidine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug Administr | 2005 |
Central sleep apnea in stable methadone maintenance treatment patients.
Topics: Adult; Female; Heroin Dependence; Humans; Hypercapnia; Hypoxia; Male; Methadone; Narcotics; Polysomn | 2005 |
Sleep-disordered breathing in stable methadone programme patients: a pilot study.
Topics: Adult; Body Mass Index; Case-Control Studies; Depression; Female; Health Status; Heroin Dependence; | 2001 |