Page last updated: 2024-10-30

methadone and Anxiety Neuroses

methadone has been researched along with Anxiety Neuroses in 25 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Research Excerpts

ExcerptRelevanceReference
" We studied the interaction between early onset and rapid transition to heroin dependence recorded with retrospective interviews in 213 patients with severe heroin dependence and history of methadone maintenance treatment."7.83Anxiety disorders are associated with early onset of heroin use and rapid transition to dependence in methadone maintained patients. ( Avril, E; Belforte, B; Bellivier, F; Bloch, V; Coeuru, P; Dupuy, G; Fortias, M; Icick, R; Jarroir, M; Karsinti, E; Ksouda, K; Laqueille, X; Lépine, JP; Orizet, C; Polomeni, P; Scott, J; Simonpoli, AM; Touzeau, D; Vorspan, F, 2016)
"This study examines prevalence rates for DSM-III-R anxiety and affective disorders in three follow-up samples of opioid addicts who were treated with methadone maintenance."5.08Psychiatric comorbidity: prevalence in methadone maintenance treatment. ( Haas, N; Huggins, N; Khuder, S; McLellan, AT; Milby, JB; Schumacher, JE; Sims, MK; Woody, G, 1996)
" Dole DD-RG) patients according to the following six discussion points: (1) Treatment of personality disorders during Methadone Maintenance Treatment (MMT); (2) Treatment of Mood Disorders during MMT; (3) Treatment of Anxiety Disorders during MMT; (4) Treatment of Psychotic Disorders during MMT; (5) Treatment of violence during MMT; (6) Treatment of Alcohol Use Disorder (AUD) during MMT."5.01What we have learned from the Methadone Maintenance Treatment of Dual Disorder Heroin Use Disorder patients. ( Maremmani, AGI; Maremmani, I; Pacini, M, 2019)
" We studied the interaction between early onset and rapid transition to heroin dependence recorded with retrospective interviews in 213 patients with severe heroin dependence and history of methadone maintenance treatment."3.83Anxiety disorders are associated with early onset of heroin use and rapid transition to dependence in methadone maintained patients. ( Avril, E; Belforte, B; Bellivier, F; Bloch, V; Coeuru, P; Dupuy, G; Fortias, M; Icick, R; Jarroir, M; Karsinti, E; Ksouda, K; Laqueille, X; Lépine, JP; Orizet, C; Polomeni, P; Scott, J; Simonpoli, AM; Touzeau, D; Vorspan, F, 2016)
" Antiviral treatment with pegylated interferon-alfa (IFN-alpha) plus ribavirin is often complicated by psychiatric adverse events, significantly affecting patients adherence."2.44Hepatitis C treatment in patients with drug addiction: clinical management of interferon-alpha-associated psychiatric side effects. ( Mauss, S; Schaefer, M, 2008)
"Amongst people on opioid maintenance treatment (OMT), chronic hepatitis C (HCV) is common but infrequently treated."1.34Hazardous alcohol consumption and other barriers to antiviral treatment among hepatitis C positive people receiving opioid maintenance treatment. ( Conigrave, KM; Haber, PS; Wallace, C; Watson, B; Whitfield, JB; Wurst, F, 2007)
"Women with ASPD were unlikely to have alcohol use disorder, but likely to have opioid use disorder."1.30Gender differences in psychiatric comorbidity among cocaine-using opiate addicts. ( Foote, J; Handelsman, L; Kang, SY; Magura, S; Rosenblum, A, 1998)
"Multiple substance use disorders were found in these patients, and more substance use disorders were found in those patients with, versus without, a non-substance use psychiatric diagnosis."1.28Clustering of multiple substance use and psychiatric diagnoses in opiate addicts. ( Bigelow, GE; Brooner, RK; Strain, EC, 1991)
" It was found that following the administration of the daily dosage of methadone, A-State was significantly reduced but no changes in A-Trait occurred."1.26State-trait anxiety in methadone maintenance patients. ( Teichman, M, 1981)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.00)18.7374
1990's12 (48.00)18.2507
2000's7 (28.00)29.6817
2010's2 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maremmani, AGI1
Pacini, M2
Maremmani, I2
Karsinti, E1
Fortias, M1
Dupuy, G1
Ksouda, K1
Laqueille, X1
Simonpoli, AM1
Touzeau, D1
Avril, E1
Orizet, C1
Belforte, B1
Coeuru, P1
Polomeni, P1
Icick, R1
Jarroir, M1
Bloch, V1
Scott, J1
Lépine, JP1
Bellivier, F1
Vorspan, F1
Rosen, D1
Smith, ML1
Reynolds, CF1
Tenore, PL1
Popovic, D1
Romano, A1
Maremmani, AG1
Perugi, G1
Deltito, J1
Akiskal, K1
Akiskal, H1
Schaefer, M1
Mauss, S1
Rademacher, S1
Dietz, R1
Haverkamp, W1
Watson, B1
Conigrave, KM1
Wallace, C1
Whitfield, JB1
Wurst, F1
Haber, PS1
Rounsaville, BJ3
Glazer, W1
Wilber, CH1
Weissman, MM2
Kleber, HD1
Kleber, H1
Wilber, C1
Teichman, M1
Chatham, LR1
Knight, K1
Joe, GW1
Simpson, DD1
Milby, JB2
Hohmann, AA1
Gentile, M1
Huggins, N2
Sims, MK2
McLellan, AT2
Woody, G2
Haas, N2
Rousar, E1
Brooner, RK2
Regier, MW1
Bigelow, GE2
Darke, S1
Swift, W1
Hall, W1
Musselman, DL1
Kell, MJ1
Khuder, S1
Schumacher, JE1
Rutherford, MJ1
Cacciola, JS1
Alterman, AI1
McKay, JR1
Magura, S1
Kang, SY1
Rosenblum, A1
Handelsman, L1
Foote, J1
Avants, SK1
Margolin, A1
Kosten, TR1
Schottenfeld, RS1
Calsyn, DA1
Wells, EA1
Fleming, C1
Saxon, AJ1
Spring, WD1
Willenbring, ML1
Maddux, TL1
Strain, EC1
Hendriks, VM1
Steer, RA1
Platt, JJ1
Metzger, DS1
Wang, RI1
Tiuseco, D1
Roh, BL1
Cho, JK1
Kochar, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Factors Associated With the Variance of Oral Methadone Dosage at Steady State of Maintenance Treatment: Description of Bio-markers of Phenotype and Genotype.[NCT00894452]210 participants (Actual)Observational2008-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for methadone and Anxiety Neuroses

ArticleYear
What we have learned from the Methadone Maintenance Treatment of Dual Disorder Heroin Use Disorder patients.
    International journal of environmental research and public health, 2019, 02-03, Volume: 16, Issue:3

    Topics: Alcoholism; Antidepressive Agents; Antipsychotic Agents; Anxiety Disorders; Craving; Drug Interactio

2019
Psychotherapeutic benefits of opioid agonist therapy.
    Journal of addictive diseases, 2008, Volume: 27, Issue:3

    Topics: Anxiety Disorders; Brain; Buprenorphine; Comorbidity; Depressive Disorder; Diagnosis, Dual (Psychiat

2008
Hepatitis C treatment in patients with drug addiction: clinical management of interferon-alpha-associated psychiatric side effects.
    Current drug abuse reviews, 2008, Volume: 1, Issue:2

    Topics: Alcoholism; Antidepressive Agents; Antiviral Agents; Anxiety Disorders; Depressive Disorder; Drug Th

2008

Trials

3 trials available for methadone and Anxiety Neuroses

ArticleYear
Short-term interpersonal psychotherapy in methadone-maintained opiate addicts.
    Archives of general psychiatry, 1983, Volume: 40, Issue:6

    Topics: Adult; Antisocial Personality Disorder; Anxiety Disorders; Clinical Trials as Topic; Depressive Diso

1983
Psychiatric comorbidity: prevalence in methadone maintenance treatment.
    The American journal of drug and alcohol abuse, 1996, Volume: 22, Issue:1

    Topics: Adult; Anxiety Disorders; Comorbidity; Female; Follow-Up Studies; Humans; Male; Methadone; Mood Diso

1996
When is less treatment better? The role of social anxiety in matching methadone patients to psychosocial treatments.
    Journal of consulting and clinical psychology, 1998, Volume: 66, Issue:6

    Topics: Adolescent; Adult; Analysis of Variance; Anxiety Disorders; Female; Humans; Male; Methadone; Opioid-

1998

Other Studies

19 other studies available for methadone and Anxiety Neuroses

ArticleYear
Anxiety disorders are associated with early onset of heroin use and rapid transition to dependence in methadone maintained patients.
    Psychiatry research, 2016, Nov-30, Volume: 245

    Topics: Adult; Age of Onset; Analgesics, Opioid; Anxiety Disorders; Female; Heroin; Heroin Dependence; Human

2016
The prevalence of mental and physical health disorders among older methadone patients.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2008, Volume: 16, Issue:6

    Topics: Aged; Alcoholism; Anxiety Disorders; Chronic Disease; Comorbidity; Depressive Disorder, Major; Femal

2008
Affective temperaments in heroin addiction.
    Journal of affective disorders, 2009, Volume: 117, Issue:3

    Topics: Adult; Alcoholism; Anxiety Disorders; Bipolar Disorder; Cohort Studies; Comorbidity; Cyclothymic Dis

2009
QT prolongation and syncope with methadone, doxepin, and a beta-blocker.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Anxiety Disorders; Doxepin; Electrocardiography; Humans; Long QT

2005
Hazardous alcohol consumption and other barriers to antiviral treatment among hepatitis C positive people receiving opioid maintenance treatment.
    Drug and alcohol review, 2007, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Alcoholism; Antiviral Agents; Anxiety Disorders; Australia; Buprenorphine; Comorb

2007
Heterogeneity of psychiatric diagnosis in treated opiate addicts.
    Archives of general psychiatry, 1982, Volume: 39, Issue:2

    Topics: Adult; Alcoholism; Anxiety Disorders; Depressive Disorder; Female; Humans; Male; Mental Disorders; M

1982
State-trait anxiety in methadone maintenance patients.
    The International journal of the addictions, 1981, Volume: 16, Issue:6

    Topics: Adult; Anxiety Disorders; Humans; Manifest Anxiety Scale; Methadone; Substance-Related Disorders

1981
Suicidality in a sample of methadone maintenance clients.
    The American journal of drug and alcohol abuse, 1995, Volume: 21, Issue:3

    Topics: Adult; Anxiety Disorders; Comorbidity; Depressive Disorder; Female; Humans; Male; Methadone; Opioid-

1995
Methadone maintenance outcome as a function of detoxification phobia.
    The American journal of psychiatry, 1994, Volume: 151, Issue:7

    Topics: Adult; Age Factors; Aged; Anxiety Disorders; Attitude to Health; Comorbidity; Depressive Disorder; E

1994
Psychiatric distress in antisocial drug abusers: relation to other personality disorders.
    Drug and alcohol dependence, 1994, Volume: 34, Issue:2

    Topics: Adult; Antisocial Personality Disorder; Anxiety Disorders; Combined Modality Therapy; Comorbidity; D

1994
Prevalence, severity and correlates of psychological morbidity among methadone maintenance clients.
    Addiction (Abingdon, England), 1994, Volume: 89, Issue:2

    Topics: Adolescent; Adult; Antisocial Personality Disorder; Anxiety Disorders; Comorbidity; Cross-Sectional

1994
Prevalence and improvement in psychopathology in opioid dependent patients participating in methadone maintenance.
    Journal of addictive diseases, 1995, Volume: 14, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Anxiety Disorders; Cohort Studies; Female; Follow-Up Studies; Human

1995
Assessment of object relations and reality testing in methadone patients.
    The American journal of psychiatry, 1996, Volume: 153, Issue:9

    Topics: Adult; Anxiety Disorders; Comorbidity; Depressive Disorder; Female; Heroin Dependence; Humans; Male;

1996
Gender differences in psychiatric comorbidity among cocaine-using opiate addicts.
    Journal of addictive diseases, 1998, Volume: 17, Issue:3

    Topics: Adult; Alcoholism; Anxiety Disorders; Cocaine-Related Disorders; Comorbidity; Female; Humans; Male;

1998
Changes in Millon Clinical Multiaxial Inventory scores among opiate addicts as a function of retention in methadone maintenance treatment and recent drug use.
    The American journal of drug and alcohol abuse, 2000, Volume: 26, Issue:2

    Topics: Adult; Antisocial Personality Disorder; Anxiety Disorders; Female; Follow-Up Studies; Humans; Male;

2000
Sexual dysfunction and psychological distress in methadone maintenance.
    The International journal of the addictions, 1992, Volume: 27, Issue:11

    Topics: Adult; Anxiety Disorders; Depressive Disorder; Female; Humans; Hyperprolactinemia; Male; Methadone;

1992
Clustering of multiple substance use and psychiatric diagnoses in opiate addicts.
    Drug and alcohol dependence, 1991, Volume: 27, Issue:2

    Topics: Adult; Antisocial Personality Disorder; Anxiety Disorders; Cluster Analysis; Cross-Sectional Studies

1991
Psychopathology in Dutch and American heroin addicts.
    The International journal of the addictions, 1990, Volume: 25, Issue:9

    Topics: Adult; Anxiety Disorders; Cross-Cultural Comparison; Depressive Disorder; Heroin Dependence; Hospita

1990
Can buspirone substitute for benzodiazepines in all anxious patients?
    NIDA research monograph, 1989, Volume: 95

    Topics: Adult; Alcoholism; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Humans; Male;

1989