Page last updated: 2024-10-30

methadone and Anochlesia

methadone has been researched along with Anochlesia in 11 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Research Excerpts

ExcerptRelevanceReference
"The potentiation of methadone-induced catalepsy in decorticated rats was mimicked in naive rats by intrastriatal (i."1.27Enhancement of opioid cataleptic response by cortical frontal deafferentation or intrastriatal injection of NMDA-receptor antagonists. ( Consolo, S; Forloni, G; Ladinsky, H; Palazzi, E, 1988)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199010 (90.91)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bulka, A1
Wiesenfeld-Hallin, Z1
Xu, XJ1
Barnett, A1
Goldstein, J1
Fiedler, E1
Taber, R1
Lal, H1
Gianutsos, G1
Puri, SK1
Ahtee, L3
Kääriäinen, K1
Vikberg, P1
Consolo, S1
Forloni, G1
Ladinsky, H1
Palazzi, E1
Ashtee, L1
Sasame, HA1
Perez-Cruet, J1
Di Chiara, G1
Tagliamonte, A1
Tagliamonte, P1
Gessa, GL1
Kääriäinen, I1
Kuschinsky, K1
Hornykiewicz, O1

Other Studies

11 other studies available for methadone and Anochlesia

ArticleYear
Differential antinociception by morphine and methadone in two sub-strains of Sprague-Dawley rats and its potentiation by dextromethorphan.
    Brain research, 2002, Jun-28, Volume: 942, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Catalepsy; Central Nervous System; Dextromethorphan; Dose-Response Rela

2002
Etonitazine-induced rigidity and its antagonism by centrally acting muscle relaxants.
    European journal of pharmacology, 1975, Volume: 30, Issue:1

    Topics: Analgesics, Opioid; Animals; Benzimidazoles; Benzyl Compounds; Catalepsy; Codeine; Cordotomy; Diethy

1975
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity.
    Life sciences, 1975, Jul-01, Volume: 17, Issue:1

    Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Cataleps

1975
Effect of cholingeric drugs on methadone-induced catalepsy and stereotypies in rats treated chronically with methadone.
    European journal of pharmacology, 1976, Volume: 39, Issue:2

    Topics: Animals; Atropine; Behavior; Catalepsy; Drug Synergism; Hexamethonium Compounds; Humans; Male; Mecam

1976
Effects of aminooxyacetic acid and baclofen on catalepsy, striatal homovanillic acid increase and antinociception caused by methadone in rats.
    Acta pharmacologica et toxicologica, 1976, Volume: 39, Issue:5

    Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Analgesia; Animals; Baclofen; Catalepsy; Corpus Stria

1976
Enhancement of opioid cataleptic response by cortical frontal deafferentation or intrastriatal injection of NMDA-receptor antagonists.
    Brain research, 1988, May-24, Volume: 449, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Catalepsy; Cerebral Cortex; Cere

1988
Catalepsy and stereotyped behaviour in rats treated chronically with methadone: relation to brain homovanillic acid content.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:8

    Topics: Animals; Behavior, Animal; Brain Chemistry; Catalepsy; Homovanillic Acid; Humans; Male; Methadone; P

1973
Evidence that methadone blocks dopamine receptors in the brain.
    Journal of neurochemistry, 1972, Volume: 19, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Basal Ganglia; Brain; Brain Chemistry; Butyrophenones; Ca

1972
The effect of narcotic analgesics on the homovanillic acid content of rat nucleus caudatus.
    European journal of pharmacology, 1973, Volume: 22, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Catalepsy; Caudate Nucleus; Codeine; Cyclazocine; Homovanilli

1973
Catalepsy and stereotypies in rats treated with methadone; relation to striatal dopamine.
    European journal of pharmacology, 1974, Volume: 27, Issue:2

    Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Catalepsy; Corpus Striatum; Dopamine; Dose

1974
Morphine catalepsy in the rat: relation to striatal dopamine metabolism.
    European journal of pharmacology, 1972, Volume: 19, Issue:1

    Topics: Animals; Apomorphine; Brain Chemistry; Catalepsy; Chlorpromazine; Corpus Striatum; Dihydroxyphenylal

1972