Page last updated: 2024-10-30

methadone and Alcohol-Related Disorders

methadone has been researched along with Alcohol-Related Disorders in 19 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Alcohol-Related Disorders: Disorders related to or resulting from abuse or misuse of alcohol.

Research Excerpts

ExcerptRelevanceReference
" One of the most efficacious treatments for cocaine abuse is contingency management (CM), but little research has explored the impact of AD on abstinence outcomes, particularly among patients in methadone maintenance."9.15Concurrent alcohol dependence among methadone-maintained cocaine abusers is associated with greater abstinence. ( Byrne, SA; Petry, NM, 2011)
"The aim of this study was to characterize the epidemiology and disease related to hepatitis C in a population attending a low-threshold methadone program."7.85Hepatitis C in a Mobile Low-Threshold Methadone Program. ( Água-Doce, I; Balsa, C; Belo, E; Coutinho, R; Lopes, P; Loureiro, R; Martins, HC; Pádua, E; Pereira, C; Silva, MJ, 2017)
" One of the most efficacious treatments for cocaine abuse is contingency management (CM), but little research has explored the impact of AD on abstinence outcomes, particularly among patients in methadone maintenance."5.15Concurrent alcohol dependence among methadone-maintained cocaine abusers is associated with greater abstinence. ( Byrne, SA; Petry, NM, 2011)
"Methadone-maintained (MM) clients who engage in excessive alcohol use are at high risk for HIV and hepatitis B virus (HBV) infection."5.14Effect of motivational interviewing on reduction of alcohol use. ( Cohen, A; de Castro, V; George, D; Greengold, B; Khalilifard, F; Leake, B; Marfisee, M; Nyamathi, A; Nyamathi, K; Shoptaw, S, 2010)
"The aim of this study was to characterize the epidemiology and disease related to hepatitis C in a population attending a low-threshold methadone program."3.85Hepatitis C in a Mobile Low-Threshold Methadone Program. ( Água-Doce, I; Balsa, C; Belo, E; Coutinho, R; Lopes, P; Loureiro, R; Martins, HC; Pádua, E; Pereira, C; Silva, MJ, 2017)
" This study explores the correlates of depression among a sample of methadone maintained treatment (MMT) adults in the Los Angeles area, and is part of a larger study on hepatitis health promotion among MMT clients who use alcohol."3.78Correlates of depressive symptoms among alcohol-using methadone maintained adults. ( Albarrán, CR; Branson, C; Khalilifard, F; Leake, B; Marfisee, M; Nyamathi, A, 2012)
"Persons with opioid use disorder (OUD) and co-occurring alcohol use disorder (AUD) are understudied and undertreated."1.62Association of Opioid Use Disorder Treatment With Alcohol-Related Acute Events. ( Bhat, NR; Bierut, LJ; Borodovsky, JT; Grucza, RA; Mintz, CM; Presnall, N; Xu, KY, 2021)
"Pregnancy is an opportune time to identify opioid dependence, facilitate conversion to opioid maintenance treatment, and coordinate care with specialists in addiction medicine, behavioral health, and social services."1.42Caring for Opioid-dependent Pregnant Women: Prenatal and Postpartum Care Considerations. ( Bogen, DL; Cochran, G; Krans, EE, 2015)
"Buprenorphine as maintenance treatment of opioid dependence during pregnancy has promise and may offer some benefits, but more research is needed, especially regarding induction of actively addicted women during pregnancy."1.38Treatment of opioid dependence in the setting of pregnancy. ( Martin, PR; Young, JL, 2012)
"Hazardous drinking, alcohol abuse, and dependence were measured using a Chinese version of the Alcohol Use Disorders Identification Test (AUDIT) and by measuring breath alcohol concentration."1.37Alcohol use problem among patients in methadone maintenance treatment in Taiwan. ( Chen, IC; Chie, WC; Chou, SY; Hwu, HG; Tan, HK; Yeh, YC; Yu, CY, 2011)
"Although it is said that drug addiction is associated with poor dental health, there is little research in this area."1.34Dentition of addiction in Queensland: poor dental status and major contributing drugs. ( Reece, AS, 2007)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.53)18.2507
2000's4 (21.05)29.6817
2010's12 (63.16)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Xu, KY1
Presnall, N1
Mintz, CM1
Borodovsky, JT1
Bhat, NR1
Bierut, LJ1
Grucza, RA1
Nyamathi, A2
Albarrán, CR1
Branson, C1
Marfisee, M2
Khalilifard, F2
Leake, B2
Soyka, M1
Krans, EE1
Cochran, G1
Bogen, DL1
Mark, TL1
Lubran, R1
McCance-Katz, EF1
Chalk, M1
Richardson, J1
Klimas, J2
Wood, E1
Nguyen, P1
Dong, H1
Milloy, MJ1
Kerr, T1
Hayashi, K1
Henihan, AM1
McCombe, G1
Swan, D1
Leahy, D1
Anderson, R1
Bury, G1
Dunne, CP1
Keenan, E1
Lambert, JS1
Meagher, D1
O'Gorman, C1
O'Toole, TP1
Saunders, J1
Shorter, GW1
Smyth, BP1
Kaner, E1
Cullen, W1
Silva, MJ1
Pereira, C1
Loureiro, R1
Balsa, C1
Lopes, P1
Água-Doce, I1
Belo, E1
Martins, HC1
Coutinho, R1
Pádua, E1
Shoptaw, S1
Cohen, A2
Greengold, B1
Nyamathi, K1
de Castro, V1
George, D1
Chen, IC1
Chie, WC1
Hwu, HG1
Chou, SY1
Yeh, YC1
Yu, CY1
Tan, HK1
Byrne, SA1
Petry, NM2
Guydish, J1
Passalacqua, E1
Tajima, B1
Chan, M1
Chun, J1
Bostrom, A1
Young, JL1
Martin, PR1
Peirce, JM1
Stitzer, ML1
Blaine, J1
Kellogg, S1
Satterfield, F1
Schwartz, M1
Krasnansky, J1
Pencer, E1
Silva-Vazquez, L1
Kirby, KC1
Royer-Malvestuto, C1
Roll, JM1
Copersino, ML1
Kolodner, K1
Li, R1
Gossop, M2
Stewart, D2
Marsden, J2
Reece, AS1
Nilssen, O1
Hirsch, R1
Rolfe, A1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Randomized Comparative Effectiveness Clinical Trial of Buprenorphine vs. Methadone for the Treatment of Opioid Dependence in Pregnancy.[NCT03098407]55 participants (Actual)Interventional2017-04-20Completed
HBV Prevention for Homeless at Risk for HBV/HCV/HIV[NCT00926146]451 participants (Actual)Interventional2009-07-31Completed
Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients[NCT01671501]614 participants (Actual)Interventional2013-03-31Completed
An Innovative Digital Smoking Cessation Intervention for Low-Income Adults With Substance Use Disorder[NCT04419922]100 participants (Actual)Observational2020-04-02Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for methadone and Alcohol-Related Disorders

ArticleYear
Alcohol use disorders in opioid maintenance therapy: prevalence, clinical correlates and treatment.
    European addiction research, 2015, Volume: 21, Issue:2

    Topics: Alcohol Drinking; Alcohol-Related Disorders; Brain; Buprenorphine; Chemical and Drug Induced Liver I

2015
Smoking prevalence in addiction treatment: a review.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2011, Volume: 13, Issue:6

    Topics: Alcohol-Related Disorders; Behavior, Addictive; Humans; Logistic Models; Methadone; Narcotics; Odds

2011

Trials

4 trials available for methadone and Alcohol-Related Disorders

ArticleYear
Feasibility of alcohol screening among patients receiving opioid treatment in primary care.
    BMC family practice, 2016, 11-05, Volume: 17, Issue:1

    Topics: Adult; Alcohol-Related Disorders; Attitude of Health Personnel; Controlled Before-After Studies; Fea

2016
Effect of motivational interviewing on reduction of alcohol use.
    Drug and alcohol dependence, 2010, Feb-01, Volume: 107, Issue:1

    Topics: Adolescent; Adult; Alcohol Drinking; Alcohol-Related Disorders; Female; Health Promotion; Hepatitis;

2010
Effect of motivational interviewing on reduction of alcohol use.
    Drug and alcohol dependence, 2010, Feb-01, Volume: 107, Issue:1

    Topics: Adolescent; Adult; Alcohol Drinking; Alcohol-Related Disorders; Female; Health Promotion; Hepatitis;

2010
Effect of motivational interviewing on reduction of alcohol use.
    Drug and alcohol dependence, 2010, Feb-01, Volume: 107, Issue:1

    Topics: Adolescent; Adult; Alcohol Drinking; Alcohol-Related Disorders; Female; Health Promotion; Hepatitis;

2010
Effect of motivational interviewing on reduction of alcohol use.
    Drug and alcohol dependence, 2010, Feb-01, Volume: 107, Issue:1

    Topics: Adolescent; Adult; Alcohol Drinking; Alcohol-Related Disorders; Female; Health Promotion; Hepatitis;

2010
Concurrent alcohol dependence among methadone-maintained cocaine abusers is associated with greater abstinence.
    Experimental and clinical psychopharmacology, 2011, Volume: 19, Issue:2

    Topics: Adult; Alcohol-Related Disorders; Cocaine-Related Disorders; Female; Follow-Up Studies; Humans; Male

2011
Effects of lower-cost incentives on stimulant abstinence in methadone maintenance treatment: a National Drug Abuse Treatment Clinical Trials Network study.
    Archives of general psychiatry, 2006, Volume: 63, Issue:2

    Topics: Adult; Alcohol-Related Disorders; Analgesics, Opioid; Behavior Therapy; Central Nervous System Stimu

2006

Other Studies

13 other studies available for methadone and Alcohol-Related Disorders

ArticleYear
Association of Opioid Use Disorder Treatment With Alcohol-Related Acute Events.
    JAMA network open, 2021, 02-01, Volume: 4, Issue:2

    Topics: Accidental Falls; Adult; Alcohol-Related Disorders; Alcoholism; Analgesics, Opioid; Buprenorphine; C

2021
Correlates of depressive symptoms among alcohol-using methadone maintained adults.
    The American journal on addictions, 2012, Volume: 21 Suppl 1

    Topics: Adult; Alcohol Drinking; Alcohol-Related Disorders; Analgesics, Opioid; Cross-Sectional Studies; Dep

2012
Caring for Opioid-dependent Pregnant Women: Prenatal and Postpartum Care Considerations.
    Clinical obstetrics and gynecology, 2015, Volume: 58, Issue:2

    Topics: Alcohol-Related Disorders; Breast Feeding; Counseling; Female; Humans; Incidence; Infant, Newborn; M

2015
Medicaid coverage of medications to treat alcohol and opioid dependence.
    Journal of substance abuse treatment, 2015, Volume: 55

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Buprenorphine, Naloxone Drug Combination

2015
The Impact of Enrolment in Methadone Maintenance Therapy on Initiation of Heavy Drinking among People Who Use Heroin.
    European addiction research, 2016, Volume: 22, Issue:4

    Topics: Adult; Alcohol-Related Disorders; Canada; Female; Heroin Dependence; Humans; Incidence; Male; Methad

2016
Hepatitis C in a Mobile Low-Threshold Methadone Program.
    European journal of gastroenterology & hepatology, 2017, Volume: 29, Issue:6

    Topics: Adult; Aged; Alcohol-Related Disorders; Coinfection; Comorbidity; Cross-Sectional Studies; Drug User

2017
Alcohol use problem among patients in methadone maintenance treatment in Taiwan.
    Journal of substance abuse treatment, 2011, Volume: 40, Issue:2

    Topics: Adult; Age Factors; Alcohol Drinking; Alcohol-Related Disorders; Alcoholism; Breath Tests; Female; F

2011
Treatment of opioid dependence in the setting of pregnancy.
    The Psychiatric clinics of North America, 2012, Volume: 35, Issue:2

    Topics: Adolescent; Alcohol-Related Disorders; Analgesics, Opioid; Buprenorphine; Child; Comorbidity; Delive

2012
Effectiveness of drug and alcohol counselling during methadone treatment: content, frequency, and duration of counselling and association with substance use outcomes.
    Addiction (Abingdon, England), 2006, Volume: 101, Issue:3

    Topics: Adult; Alcohol-Related Disorders; Cocaine-Related Disorders; Cohort Studies; Counseling; Female; Fol

2006
Dentition of addiction in Queensland: poor dental status and major contributing drugs.
    Australian dental journal, 2007, Volume: 52, Issue:2

    Topics: Adult; Age Factors; Alcohol-Related Disorders; Amphetamine-Related Disorders; Cross-Sectional Studie

2007
[Increasing drug abuse problems "down under"].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1999, May-30, Volume: 119, Issue:14

    Topics: Alcohol-Related Disorders; Australia; Heroin Dependence; Humans; Methadone; Opioid-Related Disorders

1999
Clinicians' self-assessment. Questions and answers in substance abuse treatment.
    Journal of substance abuse treatment, 1999, Volume: 17, Issue:3

    Topics: Alcohol-Related Disorders; Canada; Education, Medical, Continuing; Humans; Illicit Drugs; Methadone;

1999
Patterns of drinking and drinking outcomes among drug misusers. 1-year follow-up results.
    Journal of substance abuse treatment, 2000, Volume: 19, Issue:1

    Topics: Alcohol Drinking; Alcohol-Related Disorders; Female; Follow-Up Studies; Humans; Male; Methadone; Nar

2000