methadone has been researched along with Aggression in 24 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "According to this clinical trial, Olanzapine and Sertraline are effective in ameliorating symptoms of depression, anxiety and aggression, reducing sensitivity in interpersonal relationships and alleviating obsessive symptoms, pessimistic behaviors and somatization disorders in patients with personality disorders on methadone maintenance therapy." | 5.14 | The effect of Olanzapine and Sertraline on personality disorder in patients with methadone maintenance therapy. ( Birjandi, M; Jariani, M; Nazari, H; Saaki, M, 2010) |
| "Recent clinical studies suggest that substance use may be associated with an acceleration of the ageing process, possibly related to a deficit of stem cell number or function." | 1.35 | An intriguing association between dental and mental pathology in addicted and control subjects: a cross-sectional survey. ( Reece, AS, 2008) |
| "The results of a 2-year-study of the relationship between methadone dosage and treatment outcome are reported." | 1.26 | Comparison of the effect of high and low doses of methadone on treatment outcome. ( Alston, DC; Angle, BP; Siassi, I, 1977) |
| " In the unblocked condition, patients initially experienced an increase in positive mood, but with chronic administration there was a significant rise in psychopathology and the development of a generalized dysphoric state." | 1.26 | Psychopathology, craving, and mood during heroin acquisition: an experimental study. ( McDougle, M; McNamee, HB; Meyer, RE; Mirin, SM, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (62.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (25.00) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zarghami, M | 1 |
| Sheikhmoonesi, F | 1 |
| Ala, S | 1 |
| Yazdani, J | 1 |
| Farnia, S | 1 |
| Clair, J | 1 |
| Martin, L | 1 |
| Bond, AJ | 1 |
| O'Ryan, D | 1 |
| Davis, P | 1 |
| Curran, HV | 1 |
| Reece, AS | 1 |
| Borelli, JL | 1 |
| Luthar, SS | 1 |
| Suchman, NE | 1 |
| Jariani, M | 1 |
| Saaki, M | 1 |
| Nazari, H | 1 |
| Birjandi, M | 1 |
| Gerra, G | 2 |
| Zaimovic, A | 2 |
| Raggi, MA | 2 |
| Moi, G | 1 |
| Branchi, B | 1 |
| Moroni, M | 1 |
| Brambilla, F | 2 |
| Hasan, AM | 1 |
| Bernstein, MB | 1 |
| Marchesi, G | 1 |
| Lesser, E | 1 |
| Russ, M | 1 |
| Rifkin, A | 1 |
| Mendelowitz, AJ | 1 |
| Howe, EG | 1 |
| Puglisi-Allegra, S | 1 |
| Mele, A | 1 |
| Cabib, S | 1 |
| Krstić, SK | 1 |
| Stefanović-Denić, K | 1 |
| Beleslin, DB | 1 |
| Plonsky, M | 1 |
| Freeman, PR | 1 |
| Giusti, F | 1 |
| Delsignore, R | 1 |
| Bertacca, S | 1 |
| Lion, JR | 1 |
| Lal, H | 3 |
| Gianutsos, G | 2 |
| Puri, SK | 1 |
| Siassi, I | 1 |
| Angle, BP | 1 |
| Alston, DC | 1 |
| Glazer, WM | 1 |
| Cohn, GL | 1 |
| Mirin, SM | 1 |
| Meyer, RE | 1 |
| McNamee, HB | 1 |
| McDougle, M | 1 |
| Sheppard, C | 1 |
| Ricca, E | 1 |
| Fracchia, J | 1 |
| Merlis, S | 1 |
| Brown, BS | 1 |
| Jansen, DR | 1 |
| Benn, GJ | 1 |
| Singh, JM | 1 |
| Khantzian, EJ | 1 |
| Puri, S | 1 |
| Irwin, S | 1 |
| Kinoi, R | 1 |
| Van Sloten, M | 1 |
| Workman, MP | 1 |
3 reviews available for methadone and Aggression
| Article | Year |
|---|---|
Conceptual issues in the use of drugs for the treatment of aggression in man.
Topics: Adolescent; Adult; Aggression; Alcoholic Intoxication; Animals; Anti-Anxiety Agents; Anticonvulsants | 1975 |
Narcotic analgesics and aggression.
Topics: Aggression; Animals; Behavior, Animal; Electroshock; Humans; Methadone; Morphine; Parasympathomimeti | 1978 |
Opiate addiction: a critique of theory and some implications for treatment.
Topics: Aggression; Anger; Anxiety; Conditioning, Psychological; Depression; Euphoria; Humans; Methadone; Mo | 1974 |
4 trials available for methadone and Aggression
| Article | Year |
|---|---|
A comparative study of beneficial effects of Olanzapine and sodium valproate on aggressive behavior of patients who are on methadone maintenance therapy: a randomized triple blind clinical trial.
Topics: Adult; Aggression; Antipsychotic Agents; Benzodiazepines; Female; GABA Agents; Heroin Dependence; Hu | 2013 |
Discrepancies in perceptions of maternal aggression: implications for children of methadone-maintained mothers.
Topics: Adolescent; Aggression; Child; Child Behavior Disorders; Child, Preschool; Depression; Female; Human | 2010 |
The effect of Olanzapine and Sertraline on personality disorder in patients with methadone maintenance therapy.
Topics: Adult; Aggression; Analgesics, Opioid; Anxiety; Benzodiazepines; Borderline Personality Disorder; De | 2010 |
Experimentally induced aggressiveness in heroin-dependent patients treated with buprenorphine: comparison of patients receiving methadone and healthy subjects.
Topics: Adrenocorticotropic Hormone; Adult; Aggression; Blood Pressure; Buprenorphine; Epinephrine; Heart Ra | 2007 |
17 other studies available for methadone and Aggression
| Article | Year |
|---|---|
An experimental study of aggressive and neutral interpretative bias in opiate-dependent and opiate-abstinent men.
Topics: Adult; Aggression; Bias; Case-Control Studies; Cognition; Drug Users; Humans; Male; Methadone; Middl | 2009 |
An intriguing association between dental and mental pathology in addicted and control subjects: a cross-sectional survey.
Topics: Adolescent; Adult; Aggression; Aging; Alcohol Drinking; Amphetamine-Related Disorders; Anxiety; Atte | 2008 |
Methadone hydrochloride to prevent impulsive behavior in mental retardation: a case report.
Topics: Adult; Aggression; Disruptive, Impulse Control, and Conduct Disorders; Female; Humans; Inpatients; I | 2006 |
Do we undervalue feelings in patients who are cognitively impaired?
Topics: Aggression; Alzheimer Disease; Analgesics, Opioid; Anger; Anxiety; Brain Injuries; Cognition; Cognit | 2006 |
Involvement of endogenous opioid systems in social behavior of individually-housed mice.
Topics: Aggression; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leuci | 1984 |
Effect of morphine and morphine-like drugs on carbachol-induced fighting in cats.
Topics: Aggression; Agonistic Behavior; Animals; Carbachol; Cats; Female; Humans; Injections, Intraventricul | 1982 |
The effects of methadone on the social behavior and activity of the rat.
Topics: Aggression; Animals; Dose-Response Relationship, Drug; Female; Grooming; Humans; Methadone; Motor Ac | 1982 |
Aggressive responding of male heroin addicts under methadone treatment: psychometric and neuroendocrine correlates.
Topics: Adult; Aggression; Analysis of Variance; Area Under Curve; Blood Pressure; Catecholamines; Condition | 2001 |
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity.
Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Cataleps | 1975 |
Comparison of the effect of high and low doses of methadone on treatment outcome.
Topics: Adult; Aggression; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Female; Heroin Dep | 1977 |
Methadone maintenance in a patient on chronic hemodialysis.
Topics: Aggression; Humans; Male; Methadone; Middle Aged; Morphine Dependence; Renal Dialysis; Substance Wit | 1977 |
Psychopathology, craving, and mood during heroin acquisition: an experimental study.
Topics: Adult; Aggression; Anxiety; Depression; Drive; Emotions; Heroin; Heroin Dependence; Hostility; Human | 1976 |
Need conflicts of suburban narcotic abusers who apply to a county methadone maintenance program.
Topics: Adult; Aggression; Cannabis; Community Health Services; Conflict, Psychological; Female; Heroin Depe | 1975 |
Changes in attitude toward methadone.
Topics: Acting Out; Age Factors; Aggression; Attitude; Attitude of Health Personnel; District of Columbia; H | 1975 |
Methadone-induced behavioral changes: circular movements, aggression, and electrophysiological aspects.
Topics: Aggression; Animals; Brain; Drug Tolerance; Humans; Male; Methadone; Mice; Motor Activity; Substance | 1975 |
Effect of dopaminergic stimulation or blockade on morphine-withdrawal aggression.
Topics: Aggression; Amphetamine; Animals; Apomorphine; Dihydroxyphenylalanine; Haloperidol; Humans; Male; Me | 1973 |
Drug effects on distress-evoked behavior in mice: methodology and drug class comparisons.
Topics: Aggression; Animals; Arousal; Behavior, Animal; Chlordiazepoxide; Electric Stimulation; Electroshock | 1971 |