Page last updated: 2024-10-30

methadone and Adipocere

methadone has been researched along with Adipocere in 13 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Research Excerpts

ExcerptRelevanceReference
" The first case was due to a deadly intoxication by ecstasy and the second one to the deadly association of methadone and a possible neuroleptic malignant syndrome."4.98Postmortem Hyperthermia: Two Case Reports and a Review of the Literature. ( Franchi, A; Gambier, N; Gauchotte, G; Martrille, L; Raul, JS, 2018)
"Methadone was also proven to be detectable in all specimens sampled."1.56Skeletal tissue, a viable option in forensic toxicology? A view into post mortem cases. ( Cuypers, E; Rooseleers, L; Van de Voorde, W; Van Den Bogaert, W; Vandenbosch, M; Wuestenbergs, J, 2020)
"The results indicate that opiate addiction in humans (tolerant state) is associated with down-regulation of brain micro-opioid receptors and regulatory GRK 2/6 and beta-arrestin-2 proteins."1.32Decreased immunodensities of micro-opioid receptors, receptor kinases GRK 2/6 and beta-arrestin-2 in postmortem brains of opiate addicts. ( Ferrer-Alcón, M; García-Sevilla, JA; La Harpe, R, 2004)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's8 (61.54)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Vandenbosch, M1
Rooseleers, L1
Van Den Bogaert, W1
Wuestenbergs, J1
Van de Voorde, W1
Cuypers, E1
Brockbals, L2
Staeheli, SN2
Kraemer, T2
Steuer, AE2
Gascho, D1
Ebert, LC1
Franchi, A1
Gauchotte, G1
Gambier, N1
Raul, JS1
Martrille, L1
Jantos, R1
Skopp, G1
Holm, KM1
Linnet, K2
Lemaire, E3
Schmidt, C3
Denooz, R3
Charlier, C3
Boxho, P3
Dubois, N1
Buchard, A1
Johansen, SS1
Munkholm, J1
Fregerslev, M1
Morling, N1
Caplehorn, JR1
Drummer, OH1
Ferrer-Alcón, M1
La Harpe, R1
García-Sevilla, JA1
Levine, B1
Wu, SC1
Dixon, A1
Smialek, JE1

Reviews

1 review available for methadone and Adipocere

ArticleYear
Postmortem Hyperthermia: Two Case Reports and a Review of the Literature.
    The American journal of forensic medicine and pathology, 2018, Volume: 39, Issue:4

    Topics: Adult; Drug Overdose; Female; Fever; Humans; Male; Methadone; N-Methyl-3,4-methylenedioxyamphetamine

2018

Other Studies

12 other studies available for methadone and Adipocere

ArticleYear
Skeletal tissue, a viable option in forensic toxicology? A view into post mortem cases.
    Forensic science international, 2020, Volume: 309

    Topics: Analgesics, Opioid; Bone and Bones; Bone Marrow; Chromatography, Liquid; Forensic Toxicology; Humans

2020
Postmortem metabolomics: Correlating time-dependent concentration changes of xenobiotic and endogenous compounds.
    Drug testing and analysis, 2020, Volume: 12, Issue:8

    Topics: Adult; Aged; Autopsy; Chromatography, Liquid; Female; Forensic Toxicology; Gas Chromatography-Mass S

2020
Time-Dependent Postmortem Redistribution of Opioids in Blood and Alternative Matrices.
    Journal of analytical toxicology, 2018, Jul-01, Volume: 42, Issue:6

    Topics: Analgesics, Opioid; Autopsy; Biotransformation; Chromatography, High Pressure Liquid; Fentanyl; Fore

2018
Postmortem blood and tissue concentrations of R- and S-enantiomers of methadone and its metabolite EDDP.
    Forensic science international, 2013, Mar-10, Volume: 226, Issue:1-3

    Topics: Adult; Chromatography, Liquid; Female; Forensic Toxicology; Humans; Male; Mass Spectrometry; Methado

2013
Distribution of enantiomers of methadone and its main metabolite EDDP in human tissues and blood of postmortem cases.
    Journal of forensic sciences, 2015, Volume: 60, Issue:1

    Topics: Adult; Aged; Body Mass Index; Brain Chemistry; Female; Forensic Toxicology; Humans; Male; Methadone;

2015
Popliteal Vein Blood Sampling and the Postmortem Redistribution of Diazepam, Methadone, and Morphine.
    Journal of forensic sciences, 2016, Volume: 61, Issue:4

    Topics: Diazepam; Forensic Toxicology; Humans; Methadone; Morphine; Popliteal Vein; Postmortem Changes

2016
Postmortem Concentration and Redistribution of Diazepam, Methadone, and Morphine with Subclavian and Femoral Vein Dissection/Clamping.
    Journal of forensic sciences, 2016, Volume: 61, Issue:6

    Topics: Constriction; Diazepam; Femoral Vein; Humans; Methadone; Morphine; Postmortem Changes

2016
Site-, Technique-, and Time-Related Aspects of the Postmortem Redistribution of Diazepam, Methadone, Morphine, and their Metabolites: Interest of Popliteal Vein Blood Sampling.
    Journal of forensic sciences, 2017, Volume: 62, Issue:6

    Topics: Adult; Blood Specimen Collection; Chromatography, Liquid; Diazepam; Female; Femoral Vein; Forensic T

2017
Postmortem blood concentrations of R- and S-enantiomers of methadone and EDDP in drug users: influence of co-medication and p-glycoprotein genotype.
    Journal of forensic sciences, 2010, Mar-01, Volume: 55, Issue:2

    Topics: Adult; Analgesics; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter,

2010
Methadone dose and post-mortem blood concentration.
    Drug and alcohol review, 2002, Volume: 21, Issue:4

    Topics: Drug Overdose; Female; Humans; Male; Methadone; Postmortem Changes; Substance-Related Disorders

2002
Decreased immunodensities of micro-opioid receptors, receptor kinases GRK 2/6 and beta-arrestin-2 in postmortem brains of opiate addicts.
    Brain research. Molecular brain research, 2004, Feb-05, Volume: 121, Issue:1-2

    Topics: Adult; Arrestins; beta-Adrenergic Receptor Kinases; beta-Arrestin 2; beta-Arrestins; Case-Control St

2004
Site dependence of postmortem blood methadone concentrations.
    The American journal of forensic medicine and pathology, 1995, Volume: 16, Issue:2

    Topics: Adult; Coronary Vessels; Femoral Vein; Humans; Male; Methadone; Pericardium; Postmortem Changes; Sub

1995