methadone has been researched along with Adipocere in 13 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The first case was due to a deadly intoxication by ecstasy and the second one to the deadly association of methadone and a possible neuroleptic malignant syndrome." | 4.98 | Postmortem Hyperthermia: Two Case Reports and a Review of the Literature. ( Franchi, A; Gambier, N; Gauchotte, G; Martrille, L; Raul, JS, 2018) |
| "Methadone was also proven to be detectable in all specimens sampled." | 1.56 | Skeletal tissue, a viable option in forensic toxicology? A view into post mortem cases. ( Cuypers, E; Rooseleers, L; Van de Voorde, W; Van Den Bogaert, W; Vandenbosch, M; Wuestenbergs, J, 2020) |
| "The results indicate that opiate addiction in humans (tolerant state) is associated with down-regulation of brain micro-opioid receptors and regulatory GRK 2/6 and beta-arrestin-2 proteins." | 1.32 | Decreased immunodensities of micro-opioid receptors, receptor kinases GRK 2/6 and beta-arrestin-2 in postmortem brains of opiate addicts. ( Ferrer-Alcón, M; García-Sevilla, JA; La Harpe, R, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Vandenbosch, M | 1 |
| Rooseleers, L | 1 |
| Van Den Bogaert, W | 1 |
| Wuestenbergs, J | 1 |
| Van de Voorde, W | 1 |
| Cuypers, E | 1 |
| Brockbals, L | 2 |
| Staeheli, SN | 2 |
| Kraemer, T | 2 |
| Steuer, AE | 2 |
| Gascho, D | 1 |
| Ebert, LC | 1 |
| Franchi, A | 1 |
| Gauchotte, G | 1 |
| Gambier, N | 1 |
| Raul, JS | 1 |
| Martrille, L | 1 |
| Jantos, R | 1 |
| Skopp, G | 1 |
| Holm, KM | 1 |
| Linnet, K | 2 |
| Lemaire, E | 3 |
| Schmidt, C | 3 |
| Denooz, R | 3 |
| Charlier, C | 3 |
| Boxho, P | 3 |
| Dubois, N | 1 |
| Buchard, A | 1 |
| Johansen, SS | 1 |
| Munkholm, J | 1 |
| Fregerslev, M | 1 |
| Morling, N | 1 |
| Caplehorn, JR | 1 |
| Drummer, OH | 1 |
| Ferrer-Alcón, M | 1 |
| La Harpe, R | 1 |
| García-Sevilla, JA | 1 |
| Levine, B | 1 |
| Wu, SC | 1 |
| Dixon, A | 1 |
| Smialek, JE | 1 |
1 review available for methadone and Adipocere
| Article | Year |
|---|---|
Postmortem Hyperthermia: Two Case Reports and a Review of the Literature.
Topics: Adult; Drug Overdose; Female; Fever; Humans; Male; Methadone; N-Methyl-3,4-methylenedioxyamphetamine | 2018 |
12 other studies available for methadone and Adipocere
| Article | Year |
|---|---|
Skeletal tissue, a viable option in forensic toxicology? A view into post mortem cases.
Topics: Analgesics, Opioid; Bone and Bones; Bone Marrow; Chromatography, Liquid; Forensic Toxicology; Humans | 2020 |
Postmortem metabolomics: Correlating time-dependent concentration changes of xenobiotic and endogenous compounds.
Topics: Adult; Aged; Autopsy; Chromatography, Liquid; Female; Forensic Toxicology; Gas Chromatography-Mass S | 2020 |
Time-Dependent Postmortem Redistribution of Opioids in Blood and Alternative Matrices.
Topics: Analgesics, Opioid; Autopsy; Biotransformation; Chromatography, High Pressure Liquid; Fentanyl; Fore | 2018 |
Postmortem blood and tissue concentrations of R- and S-enantiomers of methadone and its metabolite EDDP.
Topics: Adult; Chromatography, Liquid; Female; Forensic Toxicology; Humans; Male; Mass Spectrometry; Methado | 2013 |
Distribution of enantiomers of methadone and its main metabolite EDDP in human tissues and blood of postmortem cases.
Topics: Adult; Aged; Body Mass Index; Brain Chemistry; Female; Forensic Toxicology; Humans; Male; Methadone; | 2015 |
Popliteal Vein Blood Sampling and the Postmortem Redistribution of Diazepam, Methadone, and Morphine.
Topics: Diazepam; Forensic Toxicology; Humans; Methadone; Morphine; Popliteal Vein; Postmortem Changes | 2016 |
Postmortem Concentration and Redistribution of Diazepam, Methadone, and Morphine with Subclavian and Femoral Vein Dissection/Clamping.
Topics: Constriction; Diazepam; Femoral Vein; Humans; Methadone; Morphine; Postmortem Changes | 2016 |
Site-, Technique-, and Time-Related Aspects of the Postmortem Redistribution of Diazepam, Methadone, Morphine, and their Metabolites: Interest of Popliteal Vein Blood Sampling.
Topics: Adult; Blood Specimen Collection; Chromatography, Liquid; Diazepam; Female; Femoral Vein; Forensic T | 2017 |
Postmortem blood concentrations of R- and S-enantiomers of methadone and EDDP in drug users: influence of co-medication and p-glycoprotein genotype.
Topics: Adult; Analgesics; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, | 2010 |
Methadone dose and post-mortem blood concentration.
Topics: Drug Overdose; Female; Humans; Male; Methadone; Postmortem Changes; Substance-Related Disorders | 2002 |
Decreased immunodensities of micro-opioid receptors, receptor kinases GRK 2/6 and beta-arrestin-2 in postmortem brains of opiate addicts.
Topics: Adult; Arrestins; beta-Adrenergic Receptor Kinases; beta-Arrestin 2; beta-Arrestins; Case-Control St | 2004 |
Site dependence of postmortem blood methadone concentrations.
Topics: Adult; Coronary Vessels; Femoral Vein; Humans; Male; Methadone; Pericardium; Postmortem Changes; Sub | 1995 |