methadone has been researched along with Acute Lymphoid Leukemia in 3 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Physicians should be aware of the potential interaction between voriconazole, esomeprazole and methadone leading to arrhythmia." | 3.77 | Ventricular bigeminy associated with voriconazole, methadone and esomeprazole. ( Herbrecht, R; Kemmel, V; Levêque, D; Nivoix, Y; Scholler, J, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friesen, C | 1 |
| Roscher, M | 1 |
| Hormann, I | 1 |
| Fichtner, I | 1 |
| Alt, A | 1 |
| Hilger, RA | 1 |
| Debatin, KM | 1 |
| Miltner, E | 1 |
| Singh, A | 1 |
| Jayanthan, A | 1 |
| Farran, A | 1 |
| Elwi, AN | 1 |
| Kim, SW | 1 |
| Farran, P | 1 |
| Narendran, A | 1 |
| Scholler, J | 1 |
| Nivoix, Y | 1 |
| Herbrecht, R | 1 |
| Kemmel, V | 1 |
| Levêque, D | 1 |
3 other studies available for methadone and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Cell death sensitization of leukemia cells by opioid receptor activation.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics, Opioid; Animals; Antibiotics, Antineopla | 2013 |
Induction of apoptosis in pediatric acute lymphoblastic leukemia (ALL) cells by the therapeutic opioid methadone and effective synergy with Bcl-2 inhibition.
Topics: Age Factors; Age of Onset; Analgesics, Opioid; Antineoplastic Combined Chemotherapy Protocols; Apopt | 2011 |
Ventricular bigeminy associated with voriconazole, methadone and esomeprazole.
Topics: Adult; Analgesics, Opioid; Antifungal Agents; Arrhythmias, Cardiac; Drug Interactions; Esomeprazole; | 2011 |