methadone has been researched along with Acute Kidney Injury in 13 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Objective and subjective withdrawal symptoms were measured until urine was free of drugs and patients had no withdrawal symptoms." | 2.69 | Opiate detoxification under anesthesia: no apparent benefit but suppression of thyroid hormones and risk of pulmonary and renal failure. ( Hirtl, C; Pfab, R; Zilker, T, 1999) |
| "In cases associated with coma, the pathophysiology is secondary to local pressure necrosis caused by compression from the patient's own body." | 1.26 | Rhabdomyolysis secondary to drug overdose and prolonged coma. ( Chaikin, HL, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Alzahri, MS | 1 |
| Arelin, V | 1 |
| Schmidt, JJ | 1 |
| Kayser, N | 1 |
| Kühn-Velten, WN | 1 |
| Suhling, H | 1 |
| Eden, G | 1 |
| Kielstein, JT | 1 |
| Valga-Amado, F | 1 |
| Monzón-Vázquez, TR | 1 |
| Hadad, F | 1 |
| Torrente-Sierra, J | 1 |
| Pérez-Flores, I | 1 |
| Barrientos-Guzmán, A | 1 |
| Roozen, HG | 1 |
| de Kan, R | 1 |
| van den Brink, W | 1 |
| Kerkhof, BJ | 1 |
| Geerlings, PJ | 1 |
| Nanji, AA | 1 |
| Filipenko, JD | 1 |
| Chaikin, HL | 1 |
| Lynn, KL | 1 |
| Pickering, W | 1 |
| Gardner, J | 1 |
| Bailey, RR | 1 |
| Robson, RA | 1 |
| Pfab, R | 1 |
| Hirtl, C | 1 |
| Zilker, T | 1 |
| Hojs, R | 1 |
| Sinkovic, A | 1 |
| Shilo, L | 1 |
| Liebermann, N | 1 |
| Solomon, G | 1 |
| Shenkman, L | 1 |
| Blain, PG | 1 |
| Lane, RJ | 1 |
| Bateman, DN | 1 |
| Rawlins, MD | 1 |
| Fraser, DW | 2 |
| Penn, AS | 1 |
| Rowland, LP | 1 |
1 trial available for methadone and Acute Kidney Injury
| Article | Year |
|---|---|
Opiate detoxification under anesthesia: no apparent benefit but suppression of thyroid hormones and risk of pulmonary and renal failure.
Topics: Acute Kidney Injury; Adult; Anesthesia; Codeine; Female; Heroin Dependence; Humans; Male; Methadone; | 1999 |
12 other studies available for methadone and Acute Kidney Injury
| Article | Year |
|---|---|
The Utility of Serum Creatinine Kinase in Emergency Department Patients with Possible Substance-use Related Conditions.
Topics: Acute Kidney Injury; Adult; Biomarkers; Creatine Kinase; Emergency Service, Hospital; Female; Humans | 2020 |
Removal of methadone by extended dialysis using a high cut-off dialyzer: implications for the treatment of overdose and for pain management in patients undergoing light chain removal.
Topics: Acute Kidney Injury; Adult; Analgesics, Opioid; Drug Overdose; Humans; Male; Methadone; Pain Managem | 2016 |
Rhabdomyolysis with acute renal failure secondary to taking methadone.
Topics: Acute Kidney Injury; Adult; Humans; Male; Methadone; Narcotics; Opioid-Related Disorders; Rhabdomyol | 2012 |
Dangers involved in rapid opioid detoxification while using opioid antagonists: dehydration and renal failure.
Topics: Acute Kidney Injury; Adult; Dehydration; Humans; Male; Methadone; Naltrexone; Narcotic Antagonists; | 2002 |
Rhabdomyolysis and acute myoglobinuric renal failure associated with methadone intoxication.
Topics: Acute Kidney Injury; Adult; Animals; Creatinine; Humans; Methadone; Naloxone; Rhabdomyolysis | 1983 |
Rhabdomyolysis secondary to drug overdose and prolonged coma.
Topics: Acute Kidney Injury; Adult; Coma; Humans; Hypocalcemia; Male; Mescaline; Methadone; Myoglobin; Myogl | 1980 |
Intravenous drug use and glomerular deposition of lipid-like material.
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Eosinophils; Female; Glomerular Mesangium; Hepatitis | 1998 |
Rhabdomyolysis and acute renal failure following methadone abuse.
Topics: Acute Kidney Injury; Adult; Humans; Male; Methadone; Rhabdomyolysis; Substance-Related Disorders | 1992 |
[Dangers of intravenous use of peroral methadone solutions].
Topics: Acute Kidney Injury; Administration, Oral; Adult; Humans; Injections, Intravenous; Male; Methadone; | 1986 |
Opiate-induced rhabdomyolysis.
Topics: Acute Kidney Injury; Adult; Aspartate Aminotransferases; Codeine; Creatine Kinase; Creatinine; Cycli | 1985 |
Methadone overdose. Illicit use of pharmaceutically prepared parenteral narcotics.
Topics: Acute Kidney Injury; Adult; Anuria; Apnea; Electrocardiography; Humans; Injections, Intravenous; Int | 1971 |
Drugs, coma, and myoglobinuria.
Topics: Acute Kidney Injury; Adult; Aspartate Aminotransferases; Barbiturates; Chlorpromazine; Coma; Drug-Re | 1972 |