Page last updated: 2024-10-30

methadone and Acute Disease

methadone has been researched along with Acute Disease in 48 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"As methadone use increases, the potential for methadone-induced cardiotoxicity (MIC) may rise."7.96Acute right ventricular failure: a novel presentation of methadone-induced cardiotoxicity. ( Ahmed, MM; Al-Ani, M; Dasa, O; Radhakrishnan, NS; Taha, MB; Taha, OB, 2020)
"Empirical evidence is needed to guide adequate postpartum pain relief of methadone and buprenorphine stabilized patients."7.75Management of acute postpartum pain in patients maintained on methadone or buprenorphine during pregnancy. ( Dahne, J; Johnson, R; Jones, HE; Lemoine, L; Milio, L; O'Grady, K; Ordean, A; Selby, P, 2009)
"Methadone maintained treatment (MMT) patients may be given less opioid analgesia for acute pain than the general patient, due to requests for analgesia being misinterpreted as craving for drugs."7.74Management of acute pain in methadone maintenance therapy in-patients. ( Curry, K; Fong, D; Hines, S; Theodorou, S; Williamson, A, 2008)
"Undertreatment of acute pain is suboptimal medical treatment, and patients receiving long-term OAT are at particular risk."6.43Acute pain management for patients receiving maintenance methadone or buprenorphine therapy. ( Alford, DP; Compton, P; Samet, JH, 2006)
"As methadone use increases, the potential for methadone-induced cardiotoxicity (MIC) may rise."3.96Acute right ventricular failure: a novel presentation of methadone-induced cardiotoxicity. ( Ahmed, MM; Al-Ani, M; Dasa, O; Radhakrishnan, NS; Taha, MB; Taha, OB, 2020)
"Empirical evidence is needed to guide adequate postpartum pain relief of methadone and buprenorphine stabilized patients."3.75Management of acute postpartum pain in patients maintained on methadone or buprenorphine during pregnancy. ( Dahne, J; Johnson, R; Jones, HE; Lemoine, L; Milio, L; O'Grady, K; Ordean, A; Selby, P, 2009)
"Methadone maintained treatment (MMT) patients may be given less opioid analgesia for acute pain than the general patient, due to requests for analgesia being misinterpreted as craving for drugs."3.74Management of acute pain in methadone maintenance therapy in-patients. ( Curry, K; Fong, D; Hines, S; Theodorou, S; Williamson, A, 2008)
"Environmental drug-related cues have been implicated as a cause of illicit heroin use during methadone maintenance treatment of heroin dependence."3.74Acute effect of methadone maintenance dose on brain FMRI response to heroin-related cues. ( Busch-Winokur, S; Childress, AR; Elman, I; Langleben, DD; Loughead, J; O'Brien, CP; Pratiwadi, R; Ruparel, K, 2008)
"We studied the effects of the commonly used mu-opioid receptor agonists morphine, oxycodone, methadone and the enantiomers of methadone in thermal and mechanical models of acute pain and in the spinal nerve ligation model of neuropathic pain in rats."3.73Morphine, oxycodone, methadone and its enantiomers in different models of nociception in the rat. ( Kalso, E; Kontinen, VK; Kylänlahti, I; Lemberg, K; Viljakka, K; Yli-Kauhaluoma, J, 2006)
"We describe an opioid-tolerant patient with severe acute pain which was unrelieved by morphine and ketamine via intravenous patient-controlled analgesia, but almost totally relieved by methadone."3.71Successful use of oral methadone after failure of intravenous morphine and ketamine. ( Mitchell, SJ; Sartain, JB, 2002)
" Among 42 active heroin users or former heroin addicts maintained on methadone, 79% were heavy alcohol abusers."3.65The spectrum and causes of liver diseases in narcotic addicts. ( Gelb, AM; Mildvan, D; Stenger, RJ, 1977)
"Methadone patients were hyperalgesic to pain induced by CP but not ES."2.70Methadone maintenance patients are cross-tolerant to the antinociceptive effects of morphine. ( Beare, CH; Bochner, F; Doverty, M; Ling, W; Menelaou, A; Somogyi, AA; White, JM, 2001)
"Pharmacological approaches incorporate the continuation of usual medications (or equivalent), short-term use of sometimes much higher than average doses of additional opioid, and prescription of non-opioid and adjuvant drugs, aiming to improve pain relief and attenuate opioid tolerance and/or opioid-induced hyperalgesia."2.47Acute pain management in opioid-tolerant patients: a growing challenge. ( Huxtable, CA; MacIntyre, PE; Roberts, LJ; Somogyi, AA, 2011)
"Undertreatment of acute pain is suboptimal medical treatment, and patients receiving long-term OAT are at particular risk."2.43Acute pain management for patients receiving maintenance methadone or buprenorphine therapy. ( Alford, DP; Compton, P; Samet, JH, 2006)
"The scale of drug dependence has grown dramatically in the past quarter-century."2.40WHO Expert Committee on Drug Dependence. Thirtieth report. ( , 1998)
" We initiated active surveillance for cases throughout Australia, a survey of dosing points in NSW, and a case control study of clients receiving methadone syrup (MS) at two clinics."1.34An epidemiological investigation into an outbreak of rash illness among methadone maintenance clients in Australia. ( Alam, NK; Armstrong, PK; Capon, AG; Hailstone, ST; Irvine, K; Jauncey, ME; Kaldor, JM; Mannes, TF; McAnulty, JM; Monger, CK, 2007)
"Tramadol hydrochloride is a centrally acting analgesic with a partial affinity for the opiate receptor (mu), having an analgesic potency estimated to be one tenth that of morphine."1.31Methadone detoxification of tramadol dependence. ( DeGuiseppe, B; Leo, RJ; Narendran, R, 2000)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199018 (37.50)18.7374
1990's2 (4.17)18.2507
2000's18 (37.50)29.6817
2010's9 (18.75)24.3611
2020's1 (2.08)2.80

Authors

AuthorsStudies
Taha, MB1
Dasa, O1
Al-Ani, M1
Taha, OB1
Radhakrishnan, NS1
Ahmed, MM1
Adam, VN1
Matolić, M1
Stojčić, EG1
Mršić, V1
Rašić, Ž1
Gowing, L6
Farrell, MF1
Ali, R6
White, JM4
Martín, A1
Tejerina, E1
de la Cal, MA1
Ramírez, L1
Farrell, M4
Mbewe, D1
Hines, S1
Theodorou, S1
Williamson, A1
Fong, D1
Curry, K1
Jones, HE1
O'Grady, K1
Dahne, J1
Johnson, R1
Lemoine, L1
Milio, L1
Ordean, A1
Selby, P1
Grebely, J1
Petoumenos, K1
Matthews, GV1
Haber, P1
Marks, P1
Lloyd, AR1
Kaldor, JM2
Dore, GJ1
Hellard, M1
Constantinou, N1
Morgan, CJ1
Battistella, S1
O'Ryan, D1
Davis, P1
Curran, HV1
Fredheim, OM1
Nøstdahl, T1
Nordstrand, B1
Høivik, T1
Rygnestad, T1
Borchgrevink, PC1
Huxtable, CA1
Roberts, LJ1
Somogyi, AA2
MacIntyre, PE1
Sartain, JB1
Mitchell, SJ1
Holtzman, SG1
White, J3
Fiscella, K1
Moore, A1
Engerman, J1
Meldrum, S1
Alford, DP1
Compton, P1
Samet, JH1
Lemberg, K1
Kontinen, VK1
Viljakka, K1
Kylänlahti, I1
Yli-Kauhaluoma, J1
Kalso, E1
McAnulty, JM1
Jauncey, ME1
Monger, CK1
Hailstone, ST1
Alam, NK1
Mannes, TF1
Capon, AG1
Irvine, K1
Armstrong, PK1
Langleben, DD1
Ruparel, K1
Elman, I1
Busch-Winokur, S1
Pratiwadi, R1
Loughead, J1
O'Brien, CP1
Childress, AR1
Skeie, I1
Brekke, M1
Lindbaek, M1
Waal, H1
Moryl, N1
Coyle, N1
Foley, KM1
Halpern, L1
Rizzo, F1
Birmingham, PK1
Sembach, N1
Levy, A1
Masmoudi, R1
Edel, Y1
Gratien, M1
Davido, A1
Leo, RJ1
Narendran, R1
DeGuiseppe, B1
Doverty, M1
Bochner, F1
Beare, CH1
Menelaou, A1
Ling, W1
Ishiyama, A1
Ishiyama, G1
Baloh, RW1
Evans, CJ1
Gold, MS1
Redmond, DE1
Kleber, HD1
Gelb, AM1
Mildvan, D1
Stenger, RJ1
Mirin, SM1
Meyer, RE1
McNamee, HB1
Byers, JM1
Soin, JS1
Fisher, RS1
Hutchins, GM1
Livni, N1
Steigbuegel, D1
Levu, IS1
Rothbard, MJ1
Gregory, T1
Salerno, LJ1
Gorman, E1
Warfield, CA1
Weston, MD1
Hirsch, NP1
Jones, JA1
Grosz, HJ1
Scott, ME1
Orr, R1
Eichhorn, A1
Theile, U1
Lindberg, DK1
Malik, SK1
Olivero, J1
Sutherland, N1
Dimov, D1
Beritić, T1
Kjeldgaard, JM1
Hahn, GW1
Heckenlively, JR1
Genton, E1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double Blind, Randomized Clinical Trial Comparing Postoperative Narcotic Usage in Patients Receiving Periarticular Liposomal Bupivicaine vs. Those Patients Receiving Standard Periarticular Joint Injections[NCT02682498]Phase 438 participants (Actual)Interventional2013-10-31Completed
Evaluating the Use of Sublingual Sufentanil in Patients With Suboxone Treatment Who Are Undergoing Ambulatory Surgery- a Case Series[NCT04716413]Phase 43 participants (Actual)Interventional2021-09-27Terminated (stopped due to Terminated early due to funding, lack of participants)
Feasibility, Mechanism of Action and Potential Side Effects of Extended Release Depot Naltrexone in Opioid Dependent Patients[NCT01471145]Phase 440 participants (Anticipated)Interventional2013-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

48 Hour Post-surgical Opioid Use

A comparison of group means between the control group and study group with regards to 48 hour opioid use. (NCT02682498)
Timeframe: 48 hours

Interventionmorphine equivalents (Mean)
EXPAREL® Bupivacaine Liposome Suspension5.32
Standard Periarticular Joint Injection5.07

Average Daily Opioid Use During Admission

Opioid use will be monitored daily from the time of admission in comparison of standard knee injection post-operatively. (NCT02682498)
Timeframe: Up to 48 hours

InterventionTotal Morphine Equivalents (Mean)
EXPAREL® Bupivacaine Liposome Suspension100
Standard Periarticular Joint Injection103

Average Daily Patient Pain Score

Examining the average daily patient pain score in comparison of standard knee injection post-operatively. The measure is the Visual-Analog-Scale (VAS) for subjective pain reporting. The minimum 0 (no pain) and the maximum is 10 (worst pain imagineable). There is only one measure in the scale (i.e. there are no subscales). Lower scores on the VAS scale equate to less pain and are therefore desirable. (NCT02682498)
Timeframe: Up to 48 hours

InterventionVisual Analog Scale Rating (Mean)
EXPAREL® Bupivacaine Liposome Suspension4.75
Standard Periarticular Joint Injection5.75

Post-operative Complications

Examining the post-operative complication in comparison of standard knee injection post-operatively. (NCT02682498)
Timeframe: Up to 1 month

Interventioncomplications (Number)
EXPAREL® Bupivacaine Liposome Suspension0
Standard Periarticular Joint Injection0

Recovery Room Opioid Use

Post anesthesia care unit (recovery room) opioid use in total mg morphine IV equivalent in comparison of standard knee injection post-operatively. (NCT02682498)
Timeframe: Up to 48 hours

InterventionTotal morphine equivalents (Median)
EXPAREL® Bupivacaine Liposome Suspension5
Standard Periarticular Joint Injection5

Reviews

13 reviews available for methadone and Acute Disease

ArticleYear
Alpha2-adrenergic agonists for the management of opioid withdrawal.
    The Cochrane database of systematic reviews, 2014, Mar-31, Issue:3

    Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Controlled Clinical Trials as Topic; Humans; Me

2014
Alpha₂-adrenergic agonists for the management of opioid withdrawal.
    The Cochrane database of systematic reviews, 2016, May-03, Issue:5

    Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Clonidine; Controlled Clinical Trials as Topic;

2016
Buprenorphine for managing opioid withdrawal.
    The Cochrane database of systematic reviews, 2017, 02-21, Volume: 2

    Topics: Acute Disease; Buprenorphine; Clonidine; Female; Humans; Male; Methadone; Narcotic Antagonists; Opia

2017
[Treatment of acute pain during drug-assisted rehabilitation].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2010, Apr-08, Volume: 130, Issue:7

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents

2010
Acute pain management in opioid-tolerant patients: a growing challenge.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:5

    Topics: Acute Disease; Analgesics; Analgesics, Opioid; Animals; Australia; Buprenorphine; Buprenorphine, Nal

2011
Alpha2 adrenergic agonists for the management of opioid withdrawal.
    The Cochrane database of systematic reviews, 2003, Issue:2

    Topics: Acute Disease; Controlled Clinical Trials as Topic; Humans; Methadone; Narcotics; Randomized Control

2003
Alpha2 adrenergic agonists for the management of opioid withdrawal.
    The Cochrane database of systematic reviews, 2004, Oct-18, Issue:4

    Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Controlled Clinical

2004
Acute pain management for patients receiving maintenance methadone or buprenorphine therapy.
    Annals of internal medicine, 2006, Jan-17, Volume: 144, Issue:2

    Topics: Acute Disease; Adult; Analgesics, Opioid; Buprenorphine; Female; Heroin Dependence; Humans; Methadon

2006
Recent advances in acute pain management.
    Current problems in pediatrics, 1995, Volume: 25, Issue:3

    Topics: Acute Disease; Administration, Oral; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics;

1995
WHO Expert Committee on Drug Dependence. Thirtieth report.
    World Health Organization technical report series, 1998, Volume: 873

    Topics: Acute Disease; Cost of Illness; Cost-Benefit Analysis; Health Policy; Humans; Methadone; Narcotics;

1998
Alpha2 adrenergic agonists for the management of opioid withdrawal.
    The Cochrane database of systematic reviews, 2001, Issue:1

    Topics: Acute Disease; Humans; Methadone; Narcotics; Randomized Controlled Trials as Topic; Receptors, Adren

2001
The opioid-dependent patient with acute pain.
    Hospital practice (Office ed.), 1987, Nov-15, Volume: 22, Issue:11

    Topics: Acute Disease; Humans; Methadone; Narcotics; Opioid-Related Disorders; Pain; Pain, Postoperative; Su

1987
[Antitussive agents. 34].
    Pharmazeutische Praxis, 1969, Volume: 7

    Topics: Acetylcysteine; Acute Disease; Alkaloids; Animals; Antitussive Agents; Bronchitis; Central Nervous S

1969

Trials

5 trials available for methadone and Acute Disease

ArticleYear
Factors associated with uptake of treatment for recent hepatitis C virus infection in a predominantly injecting drug user cohort: The ATAHC Study.
    Drug and alcohol dependence, 2010, Mar-01, Volume: 107, Issue:2-3

    Topics: Acute Disease; Adult; Antiviral Agents; Australia; Cohort Studies; Female; Hepacivirus; Hepatitis C;

2010
Methadone maintenance patients are cross-tolerant to the antinociceptive effects of morphine.
    Pain, 2001, Volume: 93, Issue:2

    Topics: Acute Disease; Adult; Analgesics, Opioid; Cold Temperature; Drug Interactions; Drug Tolerance; Elect

2001
Clonidine blocks acute opiate-withdrawal symptoms.
    Lancet (London, England), 1978, Sep-16, Volume: 2, Issue:8090

    Topics: Acute Disease; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Evaluation; Follow-Up

1978
Narcotic withdrawal symptoms in heroin users treated with propranolol.
    Lancet (London, England), 1972, Sep-16, Volume: 2, Issue:7777

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Female; Heroin; Hu

1972
Effects of diamorphine, methadone, morphine, and pentazocine in patients with suspected acute myocardial infarction.
    Lancet (London, England), 1969, May-31, Volume: 1, Issue:7605

    Topics: Acute Disease; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Female; Heart Rate; Heroin; Hu

1969

Other Studies

30 other studies available for methadone and Acute Disease

ArticleYear
Acute right ventricular failure: a novel presentation of methadone-induced cardiotoxicity.
    BMJ case reports, 2020, Nov-02, Volume: 13, Issue:11

    Topics: Acute Disease; Antitussive Agents; Cardiotoxicity; Drug Overdose; Female; Heart Failure; Humans; Met

2020
[ACUTE PAIN MANAGEMENT IN PATIENT ON OPIOID SUBSTITUTION THERAPY WITH\ METHADONE OR BUPRENORPHINE].
    Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 2016, Volume: 70, Issue:3

    Topics: Acute Disease; Buprenorphine; Humans; Methadone; Opiate Substitution Treatment; Pain; Pain Managemen

2016
Acute hydrocephalus secondary to carbon monoxide poisoning.
    Neurologia (Barcelona, Spain), 2016, Volume: 31, Issue:5

    Topics: Acute Disease; Adult; Benzodiazepines; Carbon Monoxide Poisoning; Humans; Hydrocephalus; Magnetic Re

2016
Management of acute pain in methadone maintenance therapy in-patients.
    Drug and alcohol review, 2008, Volume: 27, Issue:5

    Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Australia; Dose-Response Relatio

2008
Management of acute postpartum pain in patients maintained on methadone or buprenorphine during pregnancy.
    The American journal of drug and alcohol abuse, 2009, Volume: 35, Issue:3

    Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Controlled Clinic

2009
Attentional bias, inhibitory control and acute stress in current and former opiate addicts.
    Drug and alcohol dependence, 2010, Jun-01, Volume: 109, Issue:1-3

    Topics: Acute Disease; Adult; Attention; Employment; Female; Humans; Inhibition, Psychological; Male; Mental

2010
Successful use of oral methadone after failure of intravenous morphine and ketamine.
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:4

    Topics: Acute Disease; Administration, Oral; Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, O

2002
Discrimination of a single dose of morphine followed by naltrexone: substitution of other agonists for morphine and other antagonists for naltrexone in a rat model of acute dependence.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:3

    Topics: Acute Disease; Analgesics, Opioid; Animals; Disease Models, Animal; Fentanyl; Male; Methadone; Morph

2003
Management of opiate detoxification in jails.
    Journal of addictive diseases, 2005, Volume: 24, Issue:1

    Topics: Acute Disease; Adrenergic alpha-Agonists; Clonidine; Health Care Surveys; Humans; Methadone; Narcoti

2005
Morphine, oxycodone, methadone and its enantiomers in different models of nociception in the rat.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:6

    Topics: Acute Disease; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Male; Methadone; Morph

2006
An epidemiological investigation into an outbreak of rash illness among methadone maintenance clients in Australia.
    Drug and alcohol review, 2007, Volume: 26, Issue:3

    Topics: Acute Disease; Administration, Oral; Adult; Australia; Case-Control Studies; Causality; Cross-Sectio

2007
Acute effect of methadone maintenance dose on brain FMRI response to heroin-related cues.
    The American journal of psychiatry, 2008, Volume: 165, Issue:3

    Topics: Acute Disease; Adult; Analgesics, Opioid; Behavior, Addictive; Brain; Cues; Dose-Response Relationsh

2008
Somatic health among heroin addicts before and during opioid maintenance treatment: a retrospective cohort study.
    BMC public health, 2008, Jan-31, Volume: 8

    Topics: Acute Disease; Adult; Ambulatory Care; Chronic Disease; Cohort Studies; Drug Overdose; Female; Healt

2008
Managing an acute pain crisis in a patient with advanced cancer: "this is as much of a crisis as a code".
    JAMA, 2008, Mar-26, Volume: 299, Issue:12

    Topics: Acute Disease; Adenocarcinoma, Mucinous; Adjuvants, Anesthesia; Adult; Analgesics, Opioid; Anestheti

2008
Substitution-detoxification and its role in the management of chronic benign pain.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:8 Pt 2

    Topics: Acute Disease; Analgesics, Opioid; Chronic Disease; Drug Administration Schedule; Humans; Hypnotics

1982
[The need for psychopharmacologic therapy of drug addicts with acute hepatitis].
    La Clinica terapeutica, 1984, Oct-15, Volume: 111, Issue:1

    Topics: Acute Disease; Diazepam; Drug Therapy, Combination; Hepatitis; Heroin Dependence; Humans; Methadone;

1984
[Acute methadone poisoning].
    Presse medicale (Paris, France : 1983), 2000, Feb-12, Volume: 29, Issue:5

    Topics: Acute Disease; Adult; Depressive Disorder; Humans; Male; Methadone; Naloxone; Narcotic Antagonists;

2000
Methadone detoxification of tramadol dependence.
    Journal of substance abuse treatment, 2000, Volume: 19, Issue:3

    Topics: Acute Disease; Dose-Response Relationship, Drug; Female; Humans; Methadone; Middle Aged; Opioid-Rela

2000
Heroin-induced reversible profound deafness and vestibular dysfunction.
    Addiction (Abingdon, England), 2001, Volume: 96, Issue:9

    Topics: Acute Disease; Deafness; Heroin; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Narcotics;

2001
The spectrum and causes of liver diseases in narcotic addicts.
    The American journal of gastroenterology, 1977, Volume: 67, Issue:4

    Topics: Acute Disease; Alcoholism; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Chronic Disease;

1977
Psychopathology and mood during heroin use: acute vs chronic effects.
    Archives of general psychiatry, 1976, Volume: 33, Issue:12

    Topics: Acute Disease; Adult; Chronic Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination;

1976
Acute pulmonary alveolitis in narcotics abuse.
    Archives of pathology, 1975, Volume: 99, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Angiography; Cocaine; Female; Foreign Bodies; Foreign-Body Reactio

1975
Viral hepatitis with intracytoplasmic cholestasis and cholesterol crystals in a drug addict.
    The Journal of pathology, 1975, Volume: 116, Issue:1

    Topics: Acute Disease; Adolescent; Cholestasis; Cholesterol; Crystallization; Cytoplasm; Diazepam; Female; H

1975
Intrapartum gonococcal amnionitis.
    American journal of obstetrics and gynecology, 1975, Feb-15, Volume: 121, Issue:4

    Topics: Acute Disease; Adult; Amnion; Apgar Score; Female; Gonorrhea; Heroin Dependence; Humans; Infant, New

1975
Narcotic overdose and acute rhabdomyolysis.
    Anaesthesia, 1986, Volume: 41, Issue:12

    Topics: Acute Disease; Adult; Humans; Male; Methadone; Rhabdomyolysis

1986
[Therapy of acute pericarditis].
    Minerva medica, 1973, Mar-14, Volume: 64, Issue:14

    Topics: Acute Disease; Aminopyrine; Antitubercular Agents; Aspirin; Cardiac Tamponade; Chlordiazepoxide; Dia

1973
Pentazocine in methadone hydrochloride maintenance.
    JAMA, 1973, Apr-09, Volume: 224, Issue:2

    Topics: Acute Disease; Administration, Oral; Humans; Injections, Intravenous; Methadone; Pentazocine; Substa

1973
Pulmonary edema and oral ingestion of methadone.
    JAMA, 1972, Aug-21, Volume: 221, Issue:8

    Topics: Acute Disease; Administration, Oral; Adolescent; Humans; Male; Methadone; Pulmonary Edema

1972
[Acute poisoning by methadone (Heptanon)].
    Arhiv za higijenu rada i toksikologiju, 1971, Volume: 22, Issue:4

    Topics: Acute Disease; Child; Humans; Methadone; Poisoning

1971
Methadone-induced pulmonary edema.
    JAMA, 1971, Nov-08, Volume: 218, Issue:6

    Topics: Acute Disease; Administration, Oral; Adult; Coma; Female; Furosemide; Heroin; Humans; Hydrocortisone

1971