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methacrylic acid and Amyotrophic Lateral Sclerosis

methacrylic acid has been researched along with Amyotrophic Lateral Sclerosis in 1 studies

methacrylic acid: RN given refers to parent cpd
methacrylic acid : An alpha,beta-unsaturated monocarboxylic acid that is acrylic acid in which the hydrogen at position 2 is substituted by a methyl group.

Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)

Research Excerpts

ExcerptRelevanceReference
"This study aimed to develop and analyse poly(DL-lactic acid)-methacrylic acid nanospheres bound to the chelating ligand diethylenetriaminepentaacetic acid (DTPA)  for the targeted delivery of amantadine in Amyotrophic Lateral Sclerosis (ALS)."7.88Targeted Delivery of Amantadine-loaded Methacrylate Nanosphere-ligands for the Potential Treatment of Amyotrophic Lateral Sclerosis. ( Choonara, YE; Du Toit, LC; Govender, M; Indermun, S; Kumar, P; Mazibuko, Z; Modi, G; Naidoo, D; Pillay, V, 2018)
"This study aimed to develop and analyse poly(DL-lactic acid)-methacrylic acid nanospheres bound to the chelating ligand diethylenetriaminepentaacetic acid (DTPA)  for the targeted delivery of amantadine in Amyotrophic Lateral Sclerosis (ALS)."3.88Targeted Delivery of Amantadine-loaded Methacrylate Nanosphere-ligands for the Potential Treatment of Amyotrophic Lateral Sclerosis. ( Choonara, YE; Du Toit, LC; Govender, M; Indermun, S; Kumar, P; Mazibuko, Z; Modi, G; Naidoo, D; Pillay, V, 2018)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mazibuko, Z1
Indermun, S1
Govender, M1
Kumar, P1
Du Toit, LC1
Choonara, YE1
Modi, G1
Naidoo, D1
Pillay, V1

Other Studies

1 other study available for methacrylic acid and Amyotrophic Lateral Sclerosis

ArticleYear
Targeted Delivery of Amantadine-loaded Methacrylate Nanosphere-ligands for the Potential Treatment of Amyotrophic Lateral Sclerosis.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2018, Volume: 21, Issue:1

    Topics: Amantadine; Amyotrophic Lateral Sclerosis; Animals; Antiparkinson Agents; Cells, Cultured; Drug Deli

2018