Page last updated: 2024-08-17

methacholine chloride and Obesity

methacholine chloride has been researched along with Obesity in 59 studies

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.69)	18.7374
1990's	2 (3.39)	18.2507
2000's	20 (33.90)	29.6817
2010's	28 (47.46)	24.3611
2020's	8 (13.56)	2.80

Authors

Authors	Studies
Calco, GN; Fryer, AD; Jacoby, DB; Nie, Z; Proskocil, BJ	1
Ather, JL; Barup, MLT; Mank, MM; Poynter, ME; Reed, LF; Walton, CJ	1
Ahmadi, M; Alipour, MR; Aslani, MR; Boskabady, MH; Ghobadi, H; Keyhanmanesh, R; Naghizadeh, P; Saadat, S; Sharghi, A	1
Calco, GN; Fryer, AD; Jacoby, DB; Maung, JN; Nie, Z	1
Bailey, DL; Chapman, DG; Dame Carroll, JR; Farrow, CE; King, GG; Mahadev, S; Rutting, S; Thamrin, C; Tonga, KO	1
Ahmadi, M; Aslani, MR; Ghobadi, H; Heidarzadeh, M; Khaksar, M; Panahpour, H	1
Bates, JHT; Bhatawadekar, S; Daphtary, N; Dixon, AE; Hodgdon, K; Kaminsky, DA; MacLean, ES; Peters, U	1
Calco, GN; Nie, Z; Proskocil, BJ	1
Alipour, MR; Aslani, MR; Ebrahimi, H; Keyhanmanesh, R	1
Ahmadi, M; Akhavanakbari, G; Alipour, MR; Aslani, MR; Babapour, B; Keyhanmanesh, R	1
Berger, S; Bevans-Fonti, S; D'Alessio, FR; Gu, C; Hansel, NN; Lee, R; Loube, J; McCormack, MC; Mitzner, W; Nelson, A; Polotsky, VY; Shin, MK; Vieira, M; Younas, H; Zhong, Q	1
Alipour, MR; Aslani, MR; Boskabady, MH; Ghobadi, H; Keyhanmanesh, R	1
Farah, CS	1
Baron, AD; Mather, KJ; Steinberg, HO	1
Badier, M; Delpierre, S; Guillot, C	1
Berber, A; Blandon-Vijil, V; Castro-Rodriguez, JA; Del Rio-Navarro, BE; Escalante-Domínguez, AJ	1
Bourdin, A; Chanez, P; Gamez, AS; Kacimi, D; Marin, G; Molinari, N; Paganin, F; Vachier, I	1
Bastien, M; Boulet, LP; Gagnon-Audet, AA; Martin, J; Poirier, P; Simard, S; Turcotte, H	1
Aaron, SD; Baron, J; Dent, R; Pakhale, S; Vandemheen, K	1
Despins, KN; Divekar, R; Green, JA; Hartz, MF; Joshi, AY; May, SM; McWilliams, DB; Narla, N; Ott, NL; Park, MA; Pianosi, PT; Pyle, RC	1
Black, K; DeSarno, M; Dixon, AE; Holguin, F; Lane, L; Subramanian, M	1
Brothers, RM; Christmas, KM; Hurr, C; Patik, JC	1
Charron, CB; Pakhalé, S	1
Aliyeva, MI; Ather, JL; Bates, JH; Chung, M; Daphtary, NA; Dixon, AE; Forgione, PM; Georgsdottir, A; Hoyt, LR; Irvin, CG; Poynter, ME; Randall, MJ; Russell, SR; Suratt, BT	1
Milanese, M; Perrella, A; Scala, R; Scalese, M; Scichilone, N; Sposato, B	1
Berend, N; Chapman, DG; King, GG; Salome, CM	1
Shore, SA; Williams, ES; Zhu, M	1
Brusasco, V; Dellacà, R; Gobbi, A; Gulotta, C; Hyatt, RE; Pellegrino, R; Tinivella, M; Torchio, R	1
Deesomchok, A; Fisher, T; Lam, YM; Lougheed, MD; O'Donnell, DE; Ora, J; Webb, KA	1
Ben-Jebria, A; Chouchane, A; Ghannouchi, I; Miâdi-Messaoud, H; Rouatbi, S; Tabka, Z; Zbidi, A	1
Hong, SJ; Kim, BJ; Kim, BS; Kim, HB; Kim, JH; Lee, SY; Yoo, S; Yu, JH	1
Butcher, JT; Frisbee, JC; Goodwill, AG; Olfert, IM	1
Chisholm, R; Han, KA; Lteif, AA; Mather, KJ; Patel, Y	1
Desai, A; Schechter, C; Skloot, G; Togias, A	1
Baek, HS; Kim, JH; Kim, YD; Lee, HB; Oh, JW; Shin, JH	1
Bunn, JY; Dixon, AE; Forgione, PM; Garudathri, J; Griffes, LA; Irvin, CG; Kaminsky, DA; Poynter, ME; Pratley, RE; Raymond, D; Whittaker-Leclair, LA	1
Chen, L; Kasahara, DI; Shore, SA; Si, H; Williams, AS; Wurmbrand, AP	1
Hancox, RJ; Hansen, HS; Nair, P; Nybo, M; Rasmussen, F; Siersted, HC	1
Campana, LM; Deyoung, P; Hess, L; Israel, E; Malhotra, A; Owens, RL; Smales, E; Suki, B	1
Burney, P; Chinn, S; Jarvis, D	1
Johnston, RA; Rivera-Sanchez, YM; Schwartzman, IN; Shore, SA	1
HORACKOVA, E	1
Fuhlbrigge, AL; Litonjua, AA; Tantisira, KG; Weiss, ST	1
Fredberg, JJ; Johnston, RA; Rivera-Sanchez, YM; Schwartzman, IN; Shore, SA; Silverman, ES; Valone, J	1
Bergeron, C; Boulet, LP; Hamid, Q	1
Boulet, G; Boulet, LP; Robichaud, P; Simard, B; Turcotte, H	1
Jang, AS; Kim, DJ; Lee, JH; Park, CS; Park, SW; Shin, MY	1
Eagleton, LE; Henkle, JQ; Hopkins-Price, P; Sood, A; Varma, A; Verhulst, SJ	1
Cerny, FJ; Grant, BJ; Kufel, TJ; Wang, LY	1
Flynt, L; Johnston, RA; Lu, FL; Rivera-Sanchez, YM; Shore, SA; Theman, TA; Zhu, M	1
Alexeeff, SE; Litonjua, AA; Schwartz, J; Sparrow, D; Suh, H; Vokonas, PS	1
Berend, N; King, GG; Munoz, PA; Salome, CM; Schachter, LM; Thorpe, CW	1
Desouza, CA; Greiner, JJ; Stauffer, BL; Van Guilder, GP	1
Johnston, RA; Lu, FL; Shore, SA; Terry, RD; Theman, TA; Williams, ES	1
Gudbjörnsdóttir, S; Jansson, PA; Lind, L; Lönnroth, P; Murdolo, G; Sjöstrand, M; Strindberg, L	1
Baron, AD; Brechtel, G; Chaker, H; Johnson, A; Leaming, R; Steinberg, HO	1
Kam, KL; Pfaffendorf, M; van Zwieten, PA	1
Baron, AD; Cronin, J; Crowde, K; Hempfling, A; Hook, G; Paradisi, G; Steinberg, HO	1
Celedón, JC; Fang, Z; Litonjua, AA; Palmer, LJ; Wang, B; Weiss, ST; Xu, X	1

Reviews

2 review(s) available for methacholine chloride and Obesity

Article	Year
The role of airway hyperresponsiveness measured by methacholine challenge test in defining asthma severity in asthma-obesity syndrome. Current opinion in allergy and clinical immunology, 2016, Volume: 16, Issue:3 Topics: Animals; Asthma; Disease Progression; Humans; Immunization; Methacholine Chloride; Obesity; Outcome Assessment, Health Care; Severity of Illness Index; Weight Loss	2016
Obesity, allergy and immunology. The Journal of allergy and clinical immunology, 2005, Volume: 115, Issue:5 Topics: Adult; Animals; Asthma; Body Weight; Bronchial Provocation Tests; Child; Cytokines; Female; Humans; Methacholine Chloride; Obesity	2005

Trials

5 trial(s) available for methacholine chloride and Obesity

Article	Year
Influence of cardiac dysfunction and systemic inflammation on pulmonary function and airway responsiveness in obese subjects. Clinical and investigative medicine. Medecine clinique et experimentale, 2013, Oct-01, Volume: 36, Issue:5 Topics: Adult; Aged; Asthma; Blood Glucose; Bronchoconstrictor Agents; C-Reactive Protein; Female; Heart Diseases; Heart Rate; Humans; Inflammation; Lipids; Male; Methacholine Chloride; Middle Aged; Natriuretic Peptide, Brain; Obesity; Respiratory Function Tests	2013
Effects of weight loss on airway responsiveness in obese adults with asthma: does weight loss lead to reversibility of asthma? Chest, 2015, Volume: 147, Issue:6 Topics: Adult; Asthma; Body Mass Index; Bronchial Provocation Tests; Comorbidity; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Obesity; Prospective Studies; Quality of Life; Respiratory Hypersensitivity; Severity of Illness Index; Treatment Outcome; Vital Capacity; Weight Loss	2015
A pilot randomized controlled trial of pioglitazone for the treatment of poorly controlled asthma in obesity. Respiratory research, 2015, Nov-26, Volume: 16 Topics: Adult; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Double-Blind Method; Female; Humans; Lung; Male; Methacholine Chloride; Middle Aged; Obesity; Pilot Projects; Pioglitazone; Risk Factors; Thiazolidinediones; Time Factors; Treatment Outcome; Vermont; Weight Gain	2015
Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP). Thorax, 2003, Volume: 58, Issue:12 Topics: Age Distribution; Asthma; Body Mass Index; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Child; Child, Preschool; Cohort Studies; Cross-Sectional Studies; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Multivariate Analysis; Obesity; Regression Analysis; Vital Capacity	2003
Impaired endothelium-dependent vasodilation in overweight and obese adult humans is not limited to muscarinic receptor agonists. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4 Topics: Acetylcholine; Adult; Aged; Body Mass Index; Bradykinin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Infusions, Intravenous; Isoproterenol; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Obesity; Regional Blood Flow; Signal Transduction; Substance P; Vasodilation; Vasodilator Agents	2008

Other Studies

52 other study(ies) available for methacholine chloride and Obesity

Article	Year
Metformin prevents airway hyperreactivity in rats with dietary obesity. American journal of physiology. Lung cellular and molecular physiology, 2021, 12-01, Volume: 321, Issue:6 Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents; Diet, High-Fat; Female; Glucose; Hyperinsulinism; Hypoglycemic Agents; Male; Metformin; Methacholine Chloride; Obesity; Rats; Rats, Sprague-Dawley; Vagus Nerve; Weight Gain	2021
Therapeutic ketosis decreases methacholine hyperresponsiveness in mouse models of inherent obese asthma. American journal of physiology. Lung cellular and molecular physiology, 2022, 02-01, Volume: 322, Issue:2 Topics: 3-Hydroxybutyric Acid; Animals; Asthma; Bronchial Hyperreactivity; Diet, High-Fat; Diet, Ketogenic; Disease Models, Animal; Esters; Gastrointestinal Microbiome; Ketone Bodies; Ketosis; Male; Methacholine Chloride; Mice, Inbred C57BL; Obesity; Weight Loss	2022
Altered gene expression levels of IL-17/TRAF6/MAPK/USP25 axis and pro-inflammatory cytokine levels in lung tissue of obese ovalbumin-sensitized rats. Life sciences, 2022, May-01, Volume: 296 Topics: Animals; Body Weight; Cytokines; Female; Gene Expression Regulation; Interleukin-17; Lung; Male; Methacholine Chloride; Mitogen-Activated Protein Kinase Kinases; Obesity; Ovalbumin; Rats, Wistar; TNF Receptor-Associated Factor 6; Trachea; Ubiquitin Thiolesterase	2022
Insulin increases sensory nerve density and reflex bronchoconstriction in obese mice. JCI insight, 2022, 10-24, Volume: 7, Issue:20 Topics: Animals; Asthma; Bronchoconstriction; Hyperinsulinism; Insulin; Methacholine Chloride; Mice; Mice, Obese; Obesity; Receptor, Insulin; Reflex; Serotonin	2022
Obesity alters the topographical distribution of ventilation and the regional response to bronchoconstriction. Journal of applied physiology (Bethesda, Md. : 1985), 2020, 01-01, Volume: 128, Issue:1 Topics: Adolescent; Adult; Aged; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Female; Humans; Lung Volume Measurements; Male; Methacholine Chloride; Middle Aged; Obesity; Pulmonary Ventilation; Respiratory Physiological Phenomena; Single Photon Emission Computed Tomography Computed Tomography; Young Adult	2020
Modification of lung endoplasmic reticulum genes expression and NF-kB protein levels in obese ovalbumin-sensitized male and female rats. Life sciences, 2020, Apr-15, Volume: 247 Topics: Animals; Asthma; Diet, High-Fat; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Female; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Leptin; Lung; Male; Membrane Proteins; Methacholine Chloride; NF-kappa B; Obesity; Ovalbumin; Rats; Rats, Wistar; Signal Transduction; Time Factors	2020
Altered airway mechanics in the context of obesity and asthma. Journal of applied physiology (Bethesda, Md. : 1985), 2021, 01-01, Volume: 130, Issue:1 Topics: Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Humans; Methacholine Chloride; Obesity	2021
Insulin acutely increases agonist-induced airway smooth muscle contraction in humans and rats. American journal of physiology. Lung cellular and molecular physiology, 2021, 04-01, Volume: 320, Issue:4 Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Calcium; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Obesity; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Trachea; Vagus Nerve	2021
Effects of Diet-Induced Obesity on Tracheal Responsiveness to Methacholine, Tracheal Visfatin Level, and Lung Histological Changes in Ovalbumin-Sensitized Female Wistar Rats. Inflammation, 2018, Volume: 41, Issue:3 Topics: Animals; Diet, High-Fat; Female; Inflammation; Methacholine Chloride; Nicotinamide Phosphoribosyltransferase; Obesity; Ovalbumin; Rats; Rats, Wistar; Respiratory Hypersensitivity; Sensitivity and Specificity; Trachea	2018
Effect of high fat diet on NF-кB microRNA146a negative feedback loop in ovalbumin-sensitized rats. BioFactors (Oxford, England), 2019, Volume: 45, Issue:1 Topics: Allergens; Animals; Bronchial Provocation Tests; Diet, High-Fat; Feedback, Physiological; Gene Expression Regulation; Immunization; Interleukin-1 Receptor-Associated Kinases; Interleukin-1beta; Lung; Male; Methacholine Chloride; MicroRNAs; NF-kappa B; Obesity; Ovalbumin; Rats; Rats, Wistar; Signal Transduction; TNF Receptor-Associated Factor 6	2019
Caloric restriction prevents the development of airway hyperresponsiveness in mice on a high fat diet. Scientific reports, 2019, 01-22, Volume: 9, Issue:1 Topics: Animals; Caloric Restriction; Diet, High-Fat; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Methacholine Chloride; Mice; Mice, Inbred C57BL; Obesity; Respiratory Hypersensitivity	2019
Effect of High-fat Diet on Tracheal Responsiveness to Methacholine and Insulin Resistance Index in Ovalbumin-sensitized Male and Female Rats. Iranian journal of allergy, asthma, and immunology, 2019, Volume: 18, Issue:1 Topics: Allergens; Animals; Asthma; Blood Glucose; Bronchoconstrictor Agents; Diet, High-Fat; Disease Models, Animal; Female; Insulin; Insulin Resistance; Male; Methacholine Chloride; Obesity; Ovalbumin; Rats, Wistar; Trachea	2019
Airways wide shut: A physiological phenotype of asthma? Respirology (Carlton, Vic.), 2019, Volume: 24, Issue:7 Topics: Aged; Asthma; Humans; Methacholine Chloride; Obesity; Phenotype; Respiratory System	2019
Insulin resistance in the vasculature. The Journal of clinical investigation, 2013, Volume: 123, Issue:3 Topics: Blood Pressure; Body Composition; Diabetes Mellitus, Type 2; Endothelium, Vascular; Glucose; Humans; Insulin; Insulin Resistance; Methacholine Chloride; Muscle, Skeletal; Nitroprusside; Obesity; Regional Blood Flow; Vasodilation	2013
Increased asymptomatic airway hyper-responsiveness in obese individuals. The Journal of asthma : official journal of the Association for the Care of Asthma, 2013, Volume: 50, Issue:6 Topics: Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Female; Humans; Male; Methacholine Chloride; Middle Aged; Obesity; Overweight; Plethysmography; Prevalence; Spirometry	2013
Effect of obesity on bronchial hyperreactivity among Latino children. Pediatric pulmonology, 2013, Volume: 48, Issue:12 Topics: Adolescent; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Child; Cross-Sectional Studies; Female; Humans; Lung; Male; Methacholine Chloride; Mexico; Obesity; Obesity, Morbid; Respiratory Function Tests	2013
Distal airway impairment in obese normoreactive women. BioMed research international, 2013, Volume: 2013 Topics: Adult; Asthma; Body Mass Index; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Obesity; Overweight; Vital Capacity	2013
Asthma-associated comorbidities in children with and without secondhand smoke exposure. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2015, Volume: 115, Issue:3 Topics: Adolescent; Asthma; Body Mass Index; Case-Control Studies; Child; Child, Preschool; Comorbidity; Exhalation; Female; Forced Expiratory Volume; Hospitalization; Humans; Influenza Vaccines; Inhalation Exposure; Male; Methacholine Chloride; Nitric Oxide; Obesity; Retrospective Studies; Risk Factors; Severity of Illness Index; Spirometry; Tobacco Smoke Pollution; Vaccination	2015
Impaired endothelium independent vasodilation in the cutaneous microvasculature of young obese adults. Microvascular research, 2016, Volume: 104 Topics: Administration, Cutaneous; Adult; Case-Control Studies; Endothelium, Vascular; Female; Humans; Male; Methacholine Chloride; Microdialysis; Microvessels; Nitroprusside; Obesity; Skin; Vasodilation; Vasodilator Agents; Young Adult	2016
Weight Loss Decreases Inherent and Allergic Methacholine Hyperresponsiveness in Mouse Models of Diet-Induced Obese Asthma. American journal of respiratory cell and molecular biology, 2016, Volume: 55, Issue:2 Topics: Animals; Asthma; Bacteria; Bariatric Surgery; Bronchial Hyperreactivity; Cytokines; Diet; Disease Models, Animal; Hypersensitivity; Inflammation Mediators; Intestines; Male; Methacholine Chloride; Mice, Inbred C57BL; Mice, Obese; Obesity; Weight Loss	2016
Smoking and Obesity Increase Airway Hyperesponsiveness Risk in the Elderly. Current aging science, 2016, Volume: 9, Issue:4 Topics: Adolescent; Adult; Aged; Aging; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Obesity; Respiratory Hypersensitivity; Retrospective Studies; Risk Factors; Smoking; Vital Capacity; Young Adult	2016
Increased airway closure is a determinant of airway hyperresponsiveness. The European respiratory journal, 2008, Volume: 32, Issue:6 Topics: Adult; Asthma; Body Mass Index; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Female; Humans; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Obesity; Spirometry	2008
No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice. Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:4 Topics: Administration, Oral; Animals; Asthma; Blood Glucose; Body Weight; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Chemokines; Diabetes Mellitus; Disease Models, Animal; Female; Hypoglycemic Agents; Inflammation Mediators; Metformin; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Obese; Neutrophil Infiltration; Obesity; Ozone; Phenotype; Respiratory Mechanics	2008
Mechanical effects of obesity on airway responsiveness in otherwise healthy humans. Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:2 Topics: Adult; Airway Resistance; Body Mass Index; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Female; Functional Residual Capacity; Humans; Lung; Lung Volume Measurements; Male; Methacholine Chloride; Middle Aged; Obesity; Pulmonary Ventilation; Respiratory Mechanics; Sex Factors; Tidal Volume; Waist Circumference; Walking; Young Adult	2009
Effects of obesity on perceptual and mechanical responses to bronchoconstriction in asthma. American journal of respiratory and critical care medicine, 2010, Jan-15, Volume: 181, Issue:2 Topics: Adult; Asthma; Body Mass Index; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Cross-Sectional Studies; Dose-Response Relationship, Drug; Dyspnea; Female; Forced Expiratory Volume; Humans; Illness Behavior; Inspiratory Capacity; Lung Volume Measurements; Male; Methacholine Chloride; Middle Aged; Obesity; Plethysmography; Respiratory Mechanics; Sex Factors; Spirometry; Young Adult	2010
Obesity induced bronchopulmonary hyperresponsiveness in Tunisian women. International journal of obesity (2005), 2010, Volume: 34, Issue:6 Topics: Adult; Body Mass Index; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Female; Forced Expiratory Volume; Humans; Methacholine Chloride; Obesity; Tunisia; Vital Capacity	2010
Association between obesity and the prevalence of allergic diseases, atopy, and bronchial hyperresponsiveness in Korean adolescents. International archives of allergy and immunology, 2011, Volume: 154, Issue:1 Topics: Adolescent; Asthma; Body Mass Index; Bronchial Hyperreactivity; Cross-Sectional Studies; Dermatitis, Atopic; Eosinophils; Female; Humans; Hypersensitivity; Immunoglobulin E; Leukocyte Count; Male; Methacholine Chloride; Obesity; Prevalence; Republic of Korea; Respiratory Function Tests; Respiratory Sounds; Sex Factors; Skin Tests	2011
Divergence between arterial perfusion and fatigue resistance in skeletal muscle in the metabolic syndrome. Experimental physiology, 2011, Volume: 96, Issue:3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antioxidants; Arteries; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; Hyperemia; Hypertension; In Vitro Techniques; Male; Metabolic Syndrome; Methacholine Chloride; Muscle Fatigue; Muscle, Skeletal; Obesity; Oxygen; Perfusion; Peripheral Vascular Diseases; Phenylephrine; Rats; Rats, Zucker; Vasoconstriction	2011
Contributions of dysglycaemia, obesity, and insulin resistance to impaired endothelium-dependent vasodilation in humans. Diabetes/metabolism research and reviews, 2011, Volume: 27, Issue:4 Topics: Adult; Body Mass Index; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Hyperglycemia; Insulin Resistance; Leg; Male; Methacholine Chloride; Obesity; Prediabetic State; Regional Blood Flow; Severity of Illness Index; Statistics as Topic; Vascular Diseases; Vasodilation; Vasodilator Agents	2011
Impaired response to deep inspiration in obesity. Journal of applied physiology (Bethesda, Md. : 1985), 2011, Volume: 111, Issue:3 Topics: Adult; Airway Resistance; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Case-Control Studies; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Inhalation; Linear Models; Lung; Male; Methacholine Chloride; Middle Aged; Obesity; Spirometry; Vital Capacity	2011
Serum leptin and adiponectin levels correlate with exercise-induced bronchoconstriction in children with asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2011, Volume: 107, Issue:1 Topics: Adiponectin; Asthma, Exercise-Induced; Bronchoconstriction; Child; Female; Humans; Leptin; Male; Methacholine Chloride; Obesity; Respiratory Function Tests; Severity of Illness Index	2011
Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation. The Journal of allergy and clinical immunology, 2011, Volume: 128, Issue:3 Topics: Adult; Asthma; Bariatric Surgery; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes; Cross-Sectional Studies; Female; Humans; Inflammation; Male; Methacholine Chloride; Middle Aged; Obesity; Prospective Studies; Respiratory Function Tests; Treatment Outcome; Weight Loss	2011
Obesity and airway responsiveness: role of TNFR2. Pulmonary pharmacology & therapeutics, 2013, Volume: 26, Issue:4 Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Endothelins; Female; Gene Expression Regulation; Interleukin-17; Lung; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Microarray Analysis; Obesity; Receptor, trkB; Receptors, Tumor Necrosis Factor, Type II; RNA, Messenger; Signal Transduction	2013
Associations between airway hyperresponsiveness, obesity and lipoproteins in a longitudinal cohort. The clinical respiratory journal, 2013, Volume: 7, Issue:3 Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Female; Humans; Lipoproteins; Longitudinal Studies; Male; Methacholine Chloride; Muscle, Smooth; Obesity; Risk Factors; Young Adult	2013
The effect of lung stretch during sleep on airway mechanics in overweight and obese asthma. Respiratory physiology & neurobiology, 2013, Jan-15, Volume: 185, Issue:2 Topics: Adolescent; Adult; Aged; Airway Resistance; Analysis of Variance; Asthma; Body Mass Index; Female; Humans; Lung Compliance; Lung Volume Measurements; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; Obesity; Overweight; Positive-Pressure Respiration; Sleep; Wakefulness; Young Adult	2013
Relation of bronchial responsiveness to body mass index in the ECRHS. European Community Respiratory Health Survey. Thorax, 2002, Volume: 57, Issue:12 Topics: Adult; Body Mass Index; Body Weight; Bronchi; Bronchoconstrictor Agents; Female; Forced Expiratory Volume; Humans; Immunoglobulin E; Male; Methacholine Chloride; Obesity; Vital Capacity	2002
Responses to ozone are increased in obese mice. Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 95, Issue:3 Topics: Animals; Body Weight; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Cytokines; Female; Leptin; Male; Methacholine Chloride; Mice; Mice, Obese; Neutrophils; Obesity; Oxidants, Photochemical; Ozone; Phenotype; Respiratory Mechanics	2003
[EVALUATION OF THE REACTION TO THE MECHOLYL TEST USING THE THEMATIC APPERCEPTION TEST. PRELIMINARY REPORT]. Activitas nervosa superior, 1963, Volume: 5 Topics: Autonomic Nervous System; Cardiovascular Diseases; Epinephrine; Humans; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Obesity; Thematic Apperception Test	1963
Differential effects of ozone on airway and tissue mechanics in obese mice. Journal of applied physiology (Bethesda, Md. : 1985), 2004, Volume: 96, Issue:6 Topics: Animals; Bronchial Hyperreactivity; Female; Lung; Male; Methacholine Chloride; Mice; Mice, Obese; Obesity; Ozone	2004
Deep inspiration avoidance and airway response to methacholine: Influence of body mass index. Canadian respiratory journal, 2005, Volume: 12, Issue:7 Topics: Adult; Body Mass Index; Bronchial Provocation Tests; Bronchoconstrictor Agents; Female; Forced Expiratory Volume; Humans; Inhalation; Male; Methacholine Chloride; Middle Aged; Obesity	2005
Severe airway hyperresponsiveness in school-aged boys with a high body mass index. The Korean journal of internal medicine, 2006, Volume: 21, Issue:1 Topics: Age Factors; Asthma; Body Mass Index; Bronchial Hyperreactivity; Child; Comorbidity; Female; Health Surveys; Humans; Hypersensitivity, Immediate; Korea; Male; Methacholine Chloride; Obesity; Risk Factors; Schools; Sex Factors; Surveys and Questionnaires	2006
Association of excess weight and degree of airway responsiveness in asthmatics and non-asthmatics. The Journal of asthma : official journal of the Association for the Care of Asthma, 2006, Volume: 43, Issue:6 Topics: Adult; Aged; Asthma; Body Mass Index; Bronchial Hyperreactivity; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Obesity; Retrospective Studies	2006
Simulated obesity-related changes in lung volume increases airway responsiveness in lean, nonasthmatic subjects. Chest, 2006, Volume: 130, Issue:3 Topics: Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Expiratory Reserve Volume; Forced Expiratory Volume; Functional Residual Capacity; Humans; Lung; Lung Volume Measurements; Methacholine Chloride; Models, Biological; Obesity; Physical Stimulation; Pulmonary Ventilation; Random Allocation; Respiratory Function Tests	2006
Allergic airway responses in obese mice. American journal of respiratory and critical care medicine, 2007, Oct-01, Volume: 176, Issue:7 Topics: Airway Resistance; Animals; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytokines; Immunization; Immunoglobulin E; Lung; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Ovalbumin; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Respiratory Hypersensitivity; Th2 Cells	2007
Ozone exposure and lung function: effect modified by obesity and airways hyperresponsiveness in the VA normative aging study. Chest, 2007, Volume: 132, Issue:6 Topics: Aged; Aging; Bronchial Hyperreactivity; Bronchial Provocation Tests; Environmental Exposure; Forced Expiratory Volume; Humans; Likelihood Functions; Male; Methacholine Chloride; Obesity; Ozone; Regression Analysis; Spirometry; United States; Veterans; Vital Capacity	2007
Effect of obesity on breathlessness and airway responsiveness to methacholine in non-asthmatic subjects. International journal of obesity (2005), 2008, Volume: 32, Issue:3 Topics: Adolescent; Adult; Aged; Airway Resistance; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Dyspnea; Female; Forced Expiratory Volume; Functional Residual Capacity; Humans; Male; Methacholine Chloride; Middle Aged; Obesity; Vital Capacity	2008
Diet-induced obesity causes innate airway hyperresponsiveness to methacholine and enhances ozone-induced pulmonary inflammation. Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 104, Issue:6 Topics: Airway Resistance; Animals; Body Weight; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation Mediators; Injections, Intravenous; Lung Compliance; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Obesity; Ozone; Phenotype; Pneumonia; Pulmonary Edema; Respiratory Mechanics	2008
Effects of Intrabrachial metacholine infusion on muscle capillary recruitment and forearm glucose uptake during physiological hyperinsulinemia in obese, insulin-resistant individuals. The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:7 Topics: Adult; Brachial Artery; Capillaries; Forearm; Glucose; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Lactic Acid; Methacholine Chloride; Middle Aged; Muscle, Skeletal; Nitric Oxide; Obesity; Regional Blood Flow; Vasodilation	2008
Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. The Journal of clinical investigation, 1996, Jun-01, Volume: 97, Issue:11 Topics: Adult; Blood Glucose; Blood Pressure; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Endothelium, Vascular; Fatty Acids, Nonesterified; Glucose; Glucose Clamp Technique; Humans; Hyperinsulinism; Infusions, Intra-Arterial; Infusions, Intravenous; Insulin; Insulin Resistance; Leg; Methacholine Chloride; Nitroprusside; Obesity; Reference Values; Regional Blood Flow; Syndrome; Time Factors; Triglycerides; Vasodilation	1996
Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats. Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:4 Topics: Animals; Benzopyrans; Blood Glucose; Calcium Channels; Calcium Chloride; Cromakalim; Glyburide; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Methacholine Chloride; Methoxamine; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitroprusside; Norepinephrine; Obesity; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Zucker; Serotonin; Tunica Media; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents	1996
Type II diabetes abrogates sex differences in endothelial function in premenopausal women. Circulation, 2000, May-02, Volume: 101, Issue:17 Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 2; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Leg; Male; Methacholine Chloride; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Obesity; omega-N-Methylarginine; Premenopause; Risk Factors; Sex Characteristics; Vasodilator Agents	2000
Body mass index and asthma in adults in families of subjects with asthma in Anqing, China. American journal of respiratory and critical care medicine, 2001, Nov-15, Volume: 164, Issue:10 Pt 1 Topics: Adult; Age Distribution; Asthma; Body Mass Index; Bronchial Provocation Tests; Bronchoconstrictor Agents; China; Cross-Sectional Studies; Female; Humans; Logistic Models; Male; Methacholine Chloride; Multivariate Analysis; Obesity; Odds Ratio; Pedigree; Residence Characteristics; Rural Health; Sex Distribution; Smoking; Thinness	2001