Compounds > methacholine chloride
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methacholine chloride and Muscle Relaxation

methacholine chloride has been researched along with Muscle Relaxation in 86 studies

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199019 (22.09)18.7374
1990's33 (38.37)18.2507
2000's22 (25.58)29.6817
2010's11 (12.79)24.3611
2020's1 (1.16)2.80

Authors

AuthorsStudies
Chen, J; ElMallah, MK; Lifshitz, LM; Liu, Z; Lu, P; Wu, C; ZhuGe, R1
Boskabady, MH; Emami, B; Ghorani, V; Shakeri, F1
Bakhshesh, M; Boskabady, MH; Gholamnezhad, Z; Naghdi, F1
Bourque, SL; Davidge, ST; Gragasin, FS1
Emala, CW; Townsend, EA1
Bailey, SR; Bourke, JE; Donovan, C; Foster, SR; Haitsma, G; Ibrahim, ZA; Royce, SG; Tang, ML; Tran, J1
Coelho, LP; Cordeiro, RS; dos Santos, MH; Martins, MA; Pires, AL; Rodrigues e Silva, PM; Serra, MF1
Gosens, R; Häberlein, H; Meurs, H; Wolf, A1
Bennett, RT; Chaudhry, MA; Cowen, ME; Griffin, SC; Loubani, M; Morice, AH1
Choudhury, P; El Mays, TY; Green, FH; Hollenberg, MD; Saifeddine, M1
Anas, Y; Arsito, PN; Nugroho, AE; Riyanto, S; Sukari, MA; Wibowo, JT1
Ahn, K; An, SS; Koziol-White, CJ; Kurten, RC; Lee, DY; Liggett, SB; Panettieri, RA; Wang, WC1
Emala, CW; Hoonjan, B; Siviski, ME; Townsend, EA; Xu, C; Zhang, Y1
Brusasco, V; Crimi, E; Della Cioppa, G; Fabbri, LM; Francucci, B; Gherson, G; Nardelli, R; Oldani, V; Senn, S1
Ito, S; Ito, Y; Kume, H; Sudo, Y; Takagi, K; Yamaki, K1
Boskabady, MH; Jandaghi, P1
Dortch-Carnes, J; Fedan, JS; Johnston, RA; Kommineni, C; Millecchia, LL; Van Scott, MR1
Boskabady, MH; Ramazani, M; Tabei, T1
Nelemans, SA; Obels, PP; Oostendorp, J; Terpstra, AR; Zaagsma, J1
Beaulieu, MJ; Cormier, Y; Dorion, G; Israël-Assayag, E1
Boterman, M; Elzinga, CR; Eppens, PB; Meurs, H; Wagemakers, D; Zaagsma, J1
Boterman, M; Meurs, H; Smits, SR; Zaagsma, J1
Aslani, MR; Boskabady, MH; Kiani, S1
Folz, RJ; Liu, JQ; Yang, D1
Echave, V; Gomes, MM; Morin, C; Rousseau, E; Sirois, M1
Lefebvre, RA; Timmermans, JP; Van Crombruggen, K; Van Nassauw, L1
Jo, T; Martin, JG1
van Amsterdam, JG; van der Heijden, PJ; Zaagsma, J1
Bogaert, MG; Lefebvre, RA; Verplanken, PA1
Bank, CM; van der Heijden, PJ; van der Schaar, MW; Zaagsma, J1
Cheng, JB; Townley, RG1
Cade, JF; Clegg, EA; Moulds, RF; Pain, MC; Rubinfeld, AR; Santamaria, JD1
Peach, MJ; Saye, JA; Singer, HA1
Peach, MJ; Singer, HA1
Higuchi, M; Miyamoto, Y; Sakanashi, M; Takeo, S1
Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS1
Elzinga, CR; Meurs, H; Roffel, AF; Zaagsma, J1
Permutt, S; Skloot, G; Togias, A1
Heisler, S; Jia, Y; Martin, JG; Xu, L1
Bai, TR; Bramley, AM1
Kam, KL; Pfaffendorf, M; van Zwieten, PA1
Maeda, H; Nakamura, H; Nishimura, Y; Ohnishi, H; Takatsuki, K; Takenaka, K; Yahata, T; Yokoyama, M1
Bast, A; Hooijerink, H; Huf, FA; Schilt, R; Zuiderveld, OP1
Kaiser, L; Lamb, VL; Mupanomunda, M; Schwartz, AJ; Schwartz, NR; Tithof, PK; Williams, JF1
Kaiser, L; Lamb, VL; Williams, JF1
Karlsson, JA; Raeburn, D; Tomkinson, A1
Folkerts, G; Hashjin, GS; Henricks, PA; Nijkamp, FP1
Boyle, JP; Challiss, RA; Ellis, KE; Mistry, R1
Kaiser, L; Maksimowich, DS; Williams, JF1
Hüsken, BC; Pfaffendorf, M; Timmenga, EJ; Van Zwieten, PA; Vroom, MB1
Almirall, JJ; Dolman, CS; Eidelman, DH1
Kume, H; Takagi, K1
Schultz, HD; Toews, ML; Ustinova, EE1
Olszewski, MA; Robinson, NE; Zhang, XY; Zhu, FX1
Du Plooy, WJ; Kahler, CP1
Burns, GP; Gibson, GJ1
Bard, M; Blanc, FX; Coirault, C; Dartevelle, P; Dulmet, E; Fadel, E; Lecarpentier, Y; Salmeron, S1
Dortch-Carnes, J; Fedan, JS; Van Scott, MR1
Emala, C; Groeben, H1
Bogaard, JM; de Bruin, H; de Jongste, JC; Hofhuis, W; Hop, WC; Tiddens, HA; Willems, LN1
Tabrizchi, R1
Clayton, RA; MacLean, MR; McGrath, JC; Nally, JE; Thomson, NC1
Ishii, K; Moriuchi, H; Nakahara, T; Sakamato, K; Yunoki, M2
Ishii, K; Kubota, Y; Moriuchi, H; Nakahara, T; Sakamato, K; Shigenobu, K; Tanaka, Y; Yunoki, M2
Boskabady, MH; Ramazani-Assari, M1
Heijenbrok, FJ; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA1
Hirota, K; Ishihara, H; Kabara, S; Kudo, T; Matsuki, A; Yoshioka, H1
Hirshman, CA; Sauder, RA; Tobias, JD1
Hur, K; Jenne, JW; Shaughnessy, TK; Yeoh, HC1
Fernandes, LB; Fryer, AD; Hirshman, CA1
Barnes, PJ; Giembycz, MA1
Hall, IP; Hill, SJ1
Lin, PJ; Pearson, PJ; Schaff, HV1
Izzo, NJ; Loeb, AL; Peach, MJ; Singer, HA1
Angus, JA; Campbell, GR; Cocks, TM; Manderson, JA; Mosse, PR1
Miller, LG; Raeburn, D; Summer, WR1
Burman, M; Huang, LB; Torphy, TJ; Tucker, SS1
Carpenter, JR1
Fiscus, RR; Mayer, SE; Peterson, SM; Rinard, GA; Torphy, TJ; Zheng, C1
de Jongste, JC; Kerrebijn, KF; Mons, H; Sterk, PJ; Timmers, MC; Willems, LN1
Bevan, RD; Mangiarua, EI1
Burman, M; Schwartz, LW; Torphy, TJ; Wasserman, MA1
Abel, PW; Moore, DH; Puckett, AM; Rinard, GA; Walter, JB1
Armour, CL; Hogg, JC; Paré, PD; Schellenberg, RR; Taylor, SM1

Reviews

1 review(s) available for methacholine chloride and Muscle Relaxation

ArticleYear
Genetic differences in airway smooth muscle function.
    Proceedings of the American Thoracic Society, 2008, Jan-01, Volume: 5, Issue:1

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Contractile Proteins; Genetic Predisposition to Disease; Humans; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth

2008

Trials

2 trial(s) available for methacholine chloride and Muscle Relaxation

ArticleYear
Actions other than smooth muscle relaxation may play a role in the protective effects of formoterol on the allergen-induced late asthmatic reaction.
    Pulmonary pharmacology & therapeutics, 2002, Volume: 15, Issue:4

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Allergens; Asthma; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Ethanolamines; Female; Forced Expiratory Volume; Formoterol Fumarate; Humans; Male; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Time Factors

2002
Airway hyperresponsiveness in asthma: a problem of limited smooth muscle relaxation with inspiration.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:5

    Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Female; Humans; Male; Methacholine Chloride; Middle Aged; Muscle Relaxation; Muscle, Smooth

1995

Other Studies

83 other study(ies) available for methacholine chloride and Muscle Relaxation

ArticleYear
Genetic deletion of the Tas2r143/Tas2r135/Tas2r126 cluster reveals that TAS2Rs may not mediate bitter tastant-induced bronchodilation.
    Journal of cellular physiology, 2021, Volume: 236, Issue:9

    Topics: Animals; Base Sequence; Gene Deletion; Gene Expression Profiling; Ligands; Methacholine Chloride; Mice, Knockout; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Receptors, G-Protein-Coupled; Respiratory System; Taste; Tongue

2021
Relaxant effect of Curcuma longa on rat tracheal smooth muscle and its possible mechanisms.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Animals; Bronchodilator Agents; Curcuma; Dose-Response Relationship, Drug; Ethanol; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Plant Extracts; Plant Roots; Potassium Chloride; Rats; Rats, Wistar; Theophylline; Trachea

2017
Muscarinic receptors, nitric oxide formation and cyclooxygenase pathway involved in tracheal smooth muscle relaxant effect of hydro-ethanolic extract of Lavandula angustifolia flowers.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 102

    Topics: Animals; Ethanol; Female; Flowers; Lavandula; Male; Methacholine Chloride; Models, Biological; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Plant Extracts; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Trachea; Water

2018
Propofol increases vascular relaxation in aging rats chronically treated with the angiotensin-converting enzyme inhibitor captopril.
    Anesthesia and analgesia, 2013, Volume: 116, Issue:4

    Topics: Aging; Anesthetics, Intravenous; Angiotensin-Converting Enzyme Inhibitors; Animals; Area Under Curve; Blood Pressure; Captopril; Endothelium, Vascular; Enzyme Inhibitors; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phenylephrine; Propofol; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents

2013
Quercetin acutely relaxes airway smooth muscle and potentiates β-agonist-induced relaxation via dual phosphodiesterase inhibition of PLCβ and PDE4.
    American journal of physiology. Lung cellular and molecular physiology, 2013, Volume: 305, Issue:5

    Topics: Acetylcholine; Adrenergic beta-Agonists; Airway Resistance; Animals; Antioxidants; Blotting, Western; Bronchoconstrictor Agents; Calcium; Cells, Cultured; Cholinergic Agonists; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Inositol Phosphates; Isoproterenol; Male; Methacholine Chloride; Mice; Mice, Inbred A; Muscle Relaxation; Myocytes, Smooth Muscle; Nitric Oxide; Phosphodiesterase 4 Inhibitors; Phospholipase C beta; Prostaglandins; Quercetin; Respiratory System; Type C Phospholipases

2013
Rosiglitazone elicits in vitro relaxation in airways and precision cut lung slices from a mouse model of chronic allergic airways disease.
    American journal of physiology. Lung cellular and molecular physiology, 2015, Nov-15, Volume: 309, Issue:10

    Topics: Adrenergic beta-Agonists; Animals; Anti-Asthmatic Agents; Asthma; Drug Evaluation, Preclinical; Female; Guinea Pigs; Lung; Male; Methacholine Chloride; Mice, Inbred BALB C; Muscle Relaxation; Muscle, Smooth; Rosiglitazone; Thiazolidinediones; Trachea

2015
7-Epiclusianone, a tetraprenylated benzophenone, relaxes airway smooth muscle through activation of the nitric oxide-cGMP pathway.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:1

    Topics: Animals; Benzophenones; Benzoquinones; Calcium Channels; Carbachol; Cricetinae; Cyclic GMP; Epithelium; Female; Histamine; In Vitro Techniques; KATP Channels; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Parasympatholytics; Potassium Channels, Calcium-Activated; Signal Transduction; Trachea

2008
Pre-treatment with α-hederin increases β-adrenoceptor mediated relaxation of airway smooth muscle.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Jan-15, Volume: 18, Issue:2-3

    Topics: Adrenergic beta-Agonists; Animals; Bronchodilator Agents; Cattle; Drug Synergism; Hedera; Histamine; Isoproterenol; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Oleanolic Acid; Plant Extracts; Plant Leaves; Saponins; Trachea

2011
Effect of bitter tastants on human bronchi.
    Nature medicine, 2011, Jul-07, Volume: 17, Issue:7

    Topics: Bronchi; Bronchoconstriction; Dose-Response Relationship, Drug; Humans; Isoproterenol; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Quinine; Saccharin; Taste Buds

2011
Carbon dioxide enhances substance P-induced epithelium-dependent bronchial smooth muscle relaxation in Sprague-Dawley rats.
    Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:7

    Topics: Animals; Bronchi; Calcium; Carbon Dioxide; Drug Synergism; Epithelium; Hydrogen-Ion Concentration; Hypercapnia; Hypocapnia; Isoproterenol; Male; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Nifedipine; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Substance P

2011
Effects of marmin, a compound isolated from Aegle marmelos Correa, on contraction of the guinea pig-isolated trachea.
    Pakistan journal of pharmaceutical sciences, 2011, Volume: 24, Issue:4

    Topics: Aegle; Animals; Calcium Chloride; Coumarins; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; p-Methoxy-N-methylphenethylamine; Trachea

2011
TAS2R activation promotes airway smooth muscle relaxation despite β(2)-adrenergic receptor tachyphylaxis.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Aug-15, Volume: 303, Issue:4

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Chloroquine; Humans; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Mice; Muscle Relaxation; Muscle, Smooth; Receptors, Adrenergic, beta-2; Receptors, G-Protein-Coupled; Respiratory Physiological Phenomena; Respiratory System; Tachyphylaxis

2012
Effects of ginger and its constituents on airway smooth muscle relaxation and calcium regulation.
    American journal of respiratory cell and molecular biology, 2013, Volume: 48, Issue:2

    Topics: Animals; Bradykinin; Calcium; Cells, Cultured; Cricetinae; Humans; In Vitro Techniques; Male; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Plant Extracts; Trachea; Zingiber officinale

2013
Effects of direct and indirect activation of G protein of adenylyl cyclase on the subsequent response to beta-adrenergic receptor agonists in human trachealis.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:11

    Topics: Adrenergic beta-Agonists; Aged; Aged, 80 and over; Bronchoconstrictor Agents; Cholera Toxin; Enzyme Activation; Heterotrimeric GTP-Binding Proteins; Humans; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Trachea

2002
Relaxant effects of carvacrol on guinea pig tracheal chains and its possible mechanisms.
    Die Pharmazie, 2003, Volume: 58, Issue:9

    Topics: Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Central Nervous System Depressants; Cymenes; Dose-Response Relationship, Drug; Ethanol; Guinea Pigs; In Vitro Techniques; Male; Methacholine Chloride; Monoterpenes; Muscle Relaxation; Muscle, Smooth; Potassium Chloride; Theophylline; Trachea

2003
Hyperosmolar solution effects in guinea pig airways. IV. Lipopolysaccharide-induced alterations in airway reactivity and epithelial bioelectric responses to methacholine and hyperosmolarity.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:1

    Topics: Amiloride; Animals; Atropine; Bronchoconstrictor Agents; Diuretics; Drug Interactions; Electrophysiology; Enzyme Inhibitors; Epithelial Cells; Guinea Pigs; Indomethacin; Lipopolysaccharides; Male; Methacholine Chloride; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitroprusside; Osmolar Concentration; Perfusion; Respiratory Function Tests; Sodium Chloride; Trachea; Vasodilator Agents

2004
Relaxant effects of different fractions of essential oil from Carum copticum on guinea pig tracheal chains.
    Phytotherapy research : PTR, 2003, Volume: 17, Issue:10

    Topics: Animals; Bronchodilator Agents; Carum; Chlorpheniramine; Dose-Response Relationship, Drug; Ethanol; Guinea Pigs; Male; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Phytotherapy; Plant Oils; Propranolol; Theophylline; Trachea

2003
Modulation of beta2- and beta3-adrenoceptor-mediated relaxation of rat oesophagus smooth muscle by protein kinase C.
    European journal of pharmacology, 2004, Jul-08, Volume: 495, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Esophagus; Ethanolamines; Fenoterol; Formoterol Fumarate; Indoles; Male; Maleimides; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Netherlands; Phenethylamines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3

2004
Effect of 1,1-dimethylphenyl 1,4-piperazinium on mouse tracheal smooth muscle responsiveness.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 288, Issue:6

    Topics: Albuterol; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Dimethylphenylpiperazinium Iodide; Epithelium; Female; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscle Relaxation; Muscle, Smooth; Nicotinic Agonists; Receptors, Nicotinic; Trachea

2005
Potentiation of beta-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C.
    European journal of pharmacology, 2005, May-23, Volume: 516, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Cattle; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Histamine; In Vitro Techniques; Indoles; Isoproterenol; Maleimides; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Protein Kinase C; Receptors, Adrenergic, beta; Trachea

2005
Protein kinase C potentiates homologous desensitization of the beta2-adrenoceptor in bovine tracheal smooth muscle.
    European journal of pharmacology, 2006, Jan-04, Volume: 529, Issue:1-3

    Topics: Adrenergic beta-Agonists; Animals; Cattle; Dose-Response Relationship, Drug; Fenoterol; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Protein Kinase C; Receptors, Adrenergic, beta-2; Tetradecanoylphorbol Acetate; Trachea

2006
Relaxant effect of Thymus vulgaris on guinea-pig tracheal chains and its possible mechanism(s).
    Phytotherapy research : PTR, 2006, Volume: 20, Issue:1

    Topics: Animals; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Male; Methacholine Chloride; Muscle Relaxation; Phytotherapy; Plant Extracts; Potassium Chloride; Respiratory Muscles; Respiratory Tract Diseases; Statistics as Topic; Theophylline; Thymus Plant; Trachea

2006
A novel bronchial ring bioassay for the evaluation of small airway smooth muscle function in mice.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 291, Issue:2

    Topics: Animals; Biological Assay; Boron Compounds; Bronchi; Bronchoconstrictor Agents; Calcium Channel Blockers; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Methacholine Chloride; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Papaverine; Potassium Chloride; Respiratory Mucosa; Ryanodine; Stress, Mechanical; Substance P; Vasodilator Agents

2006
Relaxing effects of 5-oxo-ETE on human bronchi involve BK Ca channel activation.
    Prostaglandins & other lipid mediators, 2007, Volume: 83, Issue:4

    Topics: Arachidonic Acids; Bronchi; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Membrane Potentials; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Peptides; Potassium Channels, Calcium-Activated

2007
Inhibitory purinergic P2 receptor characterisation in rat distal colon.
    Neuropharmacology, 2007, Volume: 53, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anesthetics, Local; Animals; Colon; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Tetrodotoxin; Thionucleotides

2007
Desensitization of smooth muscle and mast cell beta-adrenoceptors in the airways of the guinea pig.
    European journal of respiratory diseases. Supplement, 1984, Volume: 135

    Topics: Adrenergic alpha-Agonists; Albuterol; Animals; Clenbuterol; Dose-Response Relationship, Drug; Fenoterol; Guinea Pigs; Isoproterenol; Lung; Mast Cells; Methacholine Chloride; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth; Receptors, Adrenergic, beta; Terbutaline; Trachea; Tretoquinol

1984
Pharmacological characterization of the postjunctional beta-adrenoceptors in the rat gastric fundus.
    European journal of pharmacology, 1984, Oct-30, Volume: 106, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Female; Gastric Fundus; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neuromuscular Junction; Rats; Receptors, Adrenergic, beta

1984
Differentiation of functional adrenoceptors in human and guinea pig airways.
    European journal of respiratory diseases. Supplement, 1984, Volume: 135

    Topics: Anaphylaxis; Animals; Bronchi; Corticosterone; Guinea Pigs; Histamine Release; Humans; Immunization; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Ovalbumin; Phenoxybenzamine; Practolol; Receptors, Adrenergic; Receptors, Neurotransmitter; Trachea

1984
Pharmacological characterization of effects of nifedipine on isolated guinea-pig and rat tracheal smooth muscle.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 263, Issue:2

    Topics: Airway Resistance; Animals; Calcium Channel Blockers; Calcium Chloride; Drug Interactions; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Pyridines; Rats; Rats, Inbred Strains; Serotonin; Trachea

1983
The potential bronchodilator action of verapamil.
    The Australian journal of experimental biology and medical science, 1984, Volume: 62 ( Pt 2)

    Topics: Animals; Barium; Barium Compounds; Bronchi; Chlorides; Dinoprost; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth; Prostaglandins F; Serotonin; Verapamil

1984
Effects of cytochrome P-450 inhibitors on endothelium-dependent relaxation in rabbit aorta.
    Blood vessels, 1984, Volume: 21, Issue:5

    Topics: Animals; Aorta; Calcium; Cytochrome P-450 Enzyme Inhibitors; Endothelium; Ionophores; Male; Methacholine Chloride; Methacholine Compounds; Metyrapone; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Proadifen; Rabbits

1984
Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Bacterial Agents; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Calcimycin; Endothelium; Indomethacin; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Prostaglandin Antagonists; Quinacrine; Rabbits

1983
Relaxant effect of trapidil on isolated dog bronchus.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 259, Issue:1

    Topics: Animals; Atropine; Bronchi; Bronchodilator Agents; Dogs; Female; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Pyrimidines; Tranylcypromine; Trapidil

1982
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
    British journal of pharmacology, 1995, Volume: 114, Issue:4

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic

1995
No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea.
    British journal of pharmacology, 1995, Volume: 115, Issue:4

    Topics: Animals; Bronchoconstrictor Agents; Cattle; Dose-Response Relationship, Drug; Gallamine Triethiodide; Histamine; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea

1995
Airways of a hyperresponsive rat strain show decreased relaxant responses to sodium nitroprusside.
    The American journal of physiology, 1995, Volume: 269, Issue:1 Pt 1

    Topics: Animals; Carbachol; Cyclic GMP; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitrites; Nitroprusside; Nucleotides, Cyclic; Rats; Rats, Inbred ACI; Rats, Inbred F344; Rats, Inbred Lew; Respiratory Hypersensitivity; Trachea

1995
Effect of an inhibitor of nitric oxide synthase on neural relaxation of human bronchi.
    The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bronchi; Chymotrypsin; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Humans; In Vitro Techniques; Isoproterenol; Lung Neoplasms; Male; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Trachea; Vasoactive Intestinal Peptide

1993
Drug-induced endothelium-dependent and -independent relaxations in isolated resistance vessels taken from simultaneously hypertensive and streptozotocin-diabetic rats.
    Blood pressure, 1994, Volume: 3, Issue:6

    Topics: Animals; Benzopyrans; Bradykinin; Calcium; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, Vascular; Glyburide; Histamine; Hypertension; Male; Mesenteric Arteries; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin; Vascular Resistance; Vasodilation; Vasodilator Agents

1994
[Bronchial hyperresponsiveness and relaxability in patients with mitral stenosis].
    Nihon Kyobu Shikkan Gakkai zasshi, 1994, Volume: 32, Issue:11

    Topics: Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Humans; Male; Methacholine Chloride; Middle Aged; Mitral Valve Stenosis; Muscle Relaxation

1994
Screening of cattle urine samples for the presence of beta-agonists with a functional test: some preliminary results.
    The Analyst, 1994, Volume: 119, Issue:12

    Topics: Adrenergic beta-Agonists; Animals; Cattle; Chromatography, Ion Exchange; Clenbuterol; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Sensitivity and Specificity; Trachea

1994
Dirofilaria immitis: depression of endothelium-dependent relaxation of canine femoral artery seen in vivo does not persist in vitro.
    Experimental parasitology, 1994, Volume: 79, Issue:2

    Topics: Animals; Arginine; Culture Techniques; Dirofilaria immitis; Dirofilariasis; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Femoral Artery; Male; Mefenamic Acid; Methacholine Chloride; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Seasons

1994
Effect of serum from dogs infected with Dirofilaria immitis on endothelium-dependent relaxation of rat aorta in vitro.
    American journal of veterinary research, 1993, Volume: 54, Issue:12

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Dirofilariasis; Dog Diseases; Dogs; Endothelium, Vascular; In Vitro Techniques; Male; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Rats; Rats, Sprague-Dawley; Vasodilation

1993
Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes.
    British journal of pharmacology, 1993, Volume: 108, Issue:1

    Topics: Albuterol; Animals; Bronchi; Cattle; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Mice; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phosphodiesterase Inhibitors; Pyridazines; Pyrrolidinones; Rolipram; Trachea

1993
Preparation of bovine tracheal smooth muscle for in vitro pharmacological studies.
    Journal of pharmacological and toxicological methods, 1995, Volume: 34, Issue:2

    Topics: Airway Resistance; Albuterol; Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle; Female; Histamine; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium Chloride; Trachea

1995
Correlation of cyclic AMP accumulation and relaxant actions of salmeterol and salbutamol in bovine tracheal smooth muscle.
    British journal of pharmacology, 1995, Volume: 116, Issue:5

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Cattle; Cyclic AMP; Histamine Antagonists; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Parasympathomimetics; Salmeterol Xinafoate; Second Messenger Systems; Trachea

1995
Thiacetarsamide depresses relaxation of canine pulmonary artery in vitro.
    Veterinary parasitology, 1996, Sep-02, Volume: 64, Issue:3

    Topics: Animals; Anthelmintics; Arsenamide; Diethylcarbamazine; Dirofilariasis; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Filaricides; In Vitro Techniques; Ivermectin; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Parasympathomimetics; Pulmonary Artery; Random Allocation; Vasodilator Agents

1996
Relaxant effect of levcromakalim in isolated human small subcutaneous arteries.
    European journal of pharmacology, 1995, Dec-20, Volume: 287, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Adolescent; Adult; Arteries; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; Female; Glyburide; Humans; In Vitro Techniques; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Skin; Thromboxane A2; Vasoconstrictor Agents

1995
Furosemide-induced bronchodilation in the rat bronchus: evidence of a role for prostaglandins.
    Lung, 1997, Volume: 175, Issue:3

    Topics: Animals; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Diuretics; Dose-Response Relationship, Drug; Furosemide; In Vitro Techniques; Indomethacin; Male; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Prostaglandins; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors

1997
Inhibitory effects of Gs on desensitization of beta-adrenergic receptors in tracheal smooth muscle.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1

    Topics: Adrenergic beta-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; GTP-Binding Proteins; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Isoproterenol; Kinetics; Male; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Receptors, Adrenergic, beta; Thionucleotides; Time Factors; Trachea

1997
Lysophosphatidic acid enhances contractility of isolated airway smooth muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 83, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Cats; Dose-Response Relationship, Drug; Endothelium; In Vitro Techniques; Isometric Contraction; Isoproterenol; Lysophospholipids; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Parasympathomimetics; Potassium Chloride; Rabbits

1997
Mechanism of capsaicin-induced relaxation in equine tracheal smooth muscle.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Charybdotoxin; Chymotrypsin; Epithelial Cells; Horses; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurons, Afferent; Neuropeptides; Nitric Oxide; Nitroarginine; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Substance P; Trachea; Vasoactive Intestinal Peptide

1997
Effect of gammalinolenic acid, dihomogammalinolenic acid, ascorbyl-6-gammalinolenic acid, and ascorbyl-6-dihomo gammalinolenic acid on histamine- and methacholine-induced contraction of the isolated guinea pig tracheal chain.
    Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 58, Issue:4

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Ascorbic Acid; Bronchoconstrictor Agents; Fatty Acids, Unsaturated; gamma-Linolenic Acid; Guinea Pigs; Histamine; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Trachea

1998
Airway hyperresponsiveness in asthma. Not just a problem of smooth muscle relaxation with inspiration.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:1

    Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Forced Expiratory Volume; Humans; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Respiratory Function Tests

1998
Effects of load and tone on the mechanics of isolated human bronchial smooth muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 86, Issue:2

    Topics: Albuterol; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Data Interpretation, Statistical; Electric Stimulation; Humans; In Vitro Techniques; Isometric Contraction; Isotonic Contraction; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth

1999
Changes in smooth muscle tone during osmotic challenge in relation to epithelial bioelectric events in guinea pig isolated trachea.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

    Topics: Animals; Bronchoconstrictor Agents; Electrophysiology; Epithelium; Guinea Pigs; In Vitro Techniques; Methacholine Chloride; Models, Biological; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Osmolar Concentration; Trachea

1999
Is beta-adrenergic-mediated airway relaxation of salmeterol antagonized by its solvent xinafoic acid?
    Chest, 1999, Volume: 115, Issue:6

    Topics: Administration, Inhalation; Airway Resistance; Albuterol; Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Dogs; Ethanol; Iodocyanopindolol; Methacholine Chloride; Muscle Relaxation; Muscle, Skeletal; Naphthols; Nebulizers and Vaporizers; Receptors, Adrenergic, beta; Salmeterol Xinafoate; Solvents

1999
Compliance, hysteresis, and collapsibility of human small airways.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:4

    Topics: Adult; Aged; Biomechanical Phenomena; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Compliance; Female; Forced Expiratory Volume; Humans; In Vitro Techniques; Isoproterenol; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Muscle Relaxation; Muscle, Smooth; Pressure; Residual Volume; Total Lung Capacity; Vital Capacity

1999
Influence of increase in osmotic pressure with sucrose on relaxation and cyclonucleotides levels in isolated rat aorta.
    European journal of pharmacology, 1999, Oct-15, Volume: 382, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Hypertonic Solutions; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Osmotic Pressure; Pinacidil; Rats; Rats, Sprague-Dawley; Sucrose; Vasodilator Agents

1999
Chronic exposure to hypoxia attenuates contractile responses in rat airways in vitro: a possible role for nitric oxide.
    European journal of pharmacology, 1999, Nov-26, Volume: 385, Issue:1

    Topics: Albuterol; Animals; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Epithelium; Hypoxia; In Vitro Techniques; Indomethacin; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Potassium Chloride; Rats; Rats, Wistar; Trachea

1999
Y-27632 potentiates relaxant effects of beta 2-adrenoceptor agonists in bovine tracheal smooth muscle.
    European journal of pharmacology, 2000, Feb-11, Volume: 389, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Amides; Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle; Intracellular Signaling Peptides and Proteins; Methacholine Chloride; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Protein Serine-Threonine Kinases; Pyridines; Receptors, Adrenergic, beta-2; rho-Associated Kinases; Terbutaline; Trachea

2000
Involvement of K(+) channel in procainamide-induced relaxation of bovine tracheal smooth muscle.
    European journal of pharmacology, 2000, Aug-18, Volume: 402, Issue:1-2

    Topics: Albuterol; Animals; Anti-Arrhythmia Agents; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle; In Vitro Techniques; Methacholine Chloride; Mexiletine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium; Potassium Channels; Procainamide; Propafenone; Quinidine; Trachea

2000
Relaxant effect of Pimpinella anisum on isolated guinea pig tracheal chains and its possible mechanism(s).
    Journal of ethnopharmacology, 2001, Volume: 74, Issue:1

    Topics: Animals; Atropine; Bronchoconstrictor Agents; Bronchodilator Agents; Guinea Pigs; Male; Methacholine Chloride; Muscle Relaxation; Oils, Volatile; Plant Extracts; Trachea

2001
The influence of chronic inhibition of nitric oxide synthesis on contractile and relaxant properties of rat carotid and mesenteric arteries.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Carotid Artery, Common; Colforsin; Endothelium, Vascular; Enzyme Inhibitors; Isometric Contraction; Isoproterenol; Male; Mesenteric Arteries; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Adrenergic, beta; Receptors, Muscarinic; Vasoconstrictor Agents; Vasodilation

2000
Role of K+ channels in N-acetylprocainamide-induced relaxation of bovine tracheal smooth muscle.
    European journal of pharmacology, 2001, Mar-09, Volume: 415, Issue:1

    Topics: Acecainide; Animals; Barium; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Procainamide; Trachea

2001
A comparison of the relaxant effects of olprinone and aminophylline on methacholine-induced bronchoconstriction in dogs.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:1

    Topics: Aminophylline; Animals; Baroreflex; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Catecholamines; Dogs; Dose-Response Relationship, Drug; Imidazoles; Methacholine Chloride; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Phosphodiesterase Inhibitors; Pyridones

2001
Lidocaine potentiates atrial natriuretic peptide-induced relaxation of bovine tracheal smooth muscle.
    European journal of pharmacology, 2001, Aug-10, Volume: 425, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Natriuretic Factor; Cattle; Cyclic GMP; Drug Interactions; Drug Synergism; In Vitro Techniques; Lidocaine; Methacholine Chloride; Mexiletine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Donors; Nitro Compounds; Nitroprusside; Trachea

2001
Methylprednisolone restores sensitivity to beta-adrenergic agonists in Basenji-Greyhound dogs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 72, Issue:2

    Topics: Adrenergic beta-Agonists; Airway Resistance; Albuterol; Aminophylline; Animals; Dogs; Drug Resistance; Lung Compliance; Methacholine Chloride; Methylprednisolone; Muscle Relaxation; Receptors, Adrenergic, beta; Time Factors

1992
Theophylline produces over-additive relaxation of canine tracheal smooth muscle when combined with beta-agonists: the dose-response relationship.
    Pulmonary pharmacology, 1992, Volume: 5, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Epithelium; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Theophylline; Trachea

1992
M2 muscarinic receptors inhibit isoproterenol-induced relaxation of canine airway smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:1

    Topics: Animals; Dogs; Drug Interactions; Isoproterenol; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea

1992
Selective inhibition of a high affinity type IV cyclic AMP phosphodiesterase in bovine trachealis by AH 21-132. Relevance to the spasmolytic and anti-spasmogenic actions of AH 21-132 in the intact tissue.
    Biochemical pharmacology, 1991, Jul-15, Volume: 42, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cattle; Cell-Free System; Chromatography, Ion Exchange; Cyclic AMP; Enzyme Activation; In Vitro Techniques; Isoenzymes; Kinetics; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Naphthyridines; Phosphodiesterase Inhibitors; Protein Kinases; Solubility; Trachea

1991
Effects of isozyme selective phosphodiesterase inhibitors on bovine tracheal smooth muscle tone.
    Biochemical pharmacology, 1992, Jan-09, Volume: 43, Issue:1

    Topics: Animals; Bronchodilator Agents; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Isoenzymes; Methacholine Chloride; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Phosphodiesterase Inhibitors; Pyrazines; Pyrrolidinones; Rolipram; Trachea

1992
Endothelium-dependent contraction and relaxation of the human and canine internal mammary artery: studies on bypass graft vasospasm.
    Surgery, 1991, Volume: 110, Issue:2

    Topics: Acetylcholine; Animals; Arginine; Dogs; Endothelins; Female; Humans; Hypoxia; In Vitro Techniques; Male; Mammary Arteries; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Norepinephrine; omega-N-Methylarginine

1991
Role of calcium in endothelium-dependent relaxation of arterial smooth muscle.
    The American journal of cardiology, 1987, Jan-23, Volume: 59, Issue:2

    Topics: Animals; Arteries; Calcimycin; Calcium; Calmodulin; Cattle; Endothelium; In Vitro Techniques; Ion Channels; Male; Methacholine Chloride; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Rabbits; Vasodilator Agents

1987
Development of a large fibromuscular intimal thickening does not impair endothelium-dependent relaxation in the rabbit carotid artery.
    Blood vessels, 1987, Volume: 24, Issue:4

    Topics: Animals; Calcimycin; Carotid Arteries; Endothelium; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Rabbits; Serotonin; Substance P; Vasodilator Agents

1987
Peripheral type benzodiazepine receptor and airway smooth muscle relaxation.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzodiazepinones; Calcium; Convulsants; Guinea Pigs; In Vitro Techniques; Ion Channels; Lung; Male; Methacholine Chloride; Methacholine Compounds; Midazolam; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium Chloride; Receptors, GABA-A; Trachea

1988
Inhibition of the low km cyclic AMP phosphodiesterase in intact canine trachealis by SK&F 94836: mechanical and biochemical responses.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bronchi; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Guanidines; Histamine; Isoproterenol; Kinetics; Methacholine Chloride; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Pyridazines; Trachea

1988
Functional antagonism of isoprenaline, salmefamol, fenoterol and pindolol by carbachol, methacholine and histamine in guinea pig isolated trachealis.
    Proceedings of the Western Pharmacology Society, 1986, Volume: 29

    Topics: Adrenergic beta-Agonists; Animals; Carbachol; Guinea Pigs; Histamine; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Muscle Relaxation; Parasympatholytics; Trachea

1986
Inhibitory effect of methacholine on drug-induced relaxation, cyclic AMP accumulation, and cyclic AMP-dependent protein kinase activation in canine tracheal smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Dogs; Enzyme Activation; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth; Prostaglandins E; Protein Kinases; Trachea

1985
Comparison of maximal bronchoconstriction in vivo and airway smooth muscle responses in vitro in nonasthmatic humans.
    The American review of respiratory disease, 1988, Volume: 138, Issue:2

    Topics: Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth

1988
Altered endothelium-mediated relaxation after denervation of growing rabbit ear artery.
    European journal of pharmacology, 1986, Mar-11, Volume: 122, Issue:1

    Topics: Animals; Arteries; Ear, External; Endothelium; Male; Methacholine Chloride; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Rabbits; Receptors, Muscarinic; Time Factors

1986
Differential effects of methacholine and leukotriene D4 on cyclic nucleotide content and isoproterenol-induced relaxation in the opossum trachea.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:1

    Topics: Airway Resistance; Animals; Female; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth; Nucleotides, Cyclic; Opossums; SRS-A; Time Factors; Trachea

1986
Regional differences in relaxation of electric field-stimulated canine airway smooth muscle by verapamil, isoproterenol and prostaglandin E2.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Animals; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Prostaglandins E; Respiratory System; Tissue Distribution; Verapamil

1986
Airway reactivity in chronic obstructive pulmonary disease. Failure of in vivo methacholine responsiveness to correlate with cholinergic, adrenergic, or nonadrenergic responses in vitro.
    The American review of respiratory disease, 1985, Volume: 132, Issue:1

    Topics: Aged; Albuterol; Bronchi; Bronchial Provocation Tests; Colforsin; Diterpenes; Female; Forced Expiratory Volume; Humans; In Vitro Techniques; Lung Diseases, Obstructive; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Pneumonectomy

1985