methacholine chloride has been researched along with Muscle Contraction in 290 studies
*Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 79 (27.24) | 18.7374 |
| 1990's | 91 (31.38) | 18.2507 |
| 2000's | 64 (22.07) | 29.6817 |
| 2010's | 44 (15.17) | 24.3611 |
| 2020's | 12 (4.14) | 2.80 |
| Authors | Studies |
|---|---|
| Bill, R; Hagedorn, I; Kuhnen-Clausen, D | 1 |
| Bossé, Y; Boucher, M; Brunet, D; Dufour-Mailhot, A; Fereydoonzad, L; Henry, C; Khadangi, F; Robichaud, A; Tremblay-Pitre, S | 1 |
| Hennenberg, M; Huang, R; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R | 1 |
| Bossé, Y; Boucher, M; Dufour-Mailhot, A; Henry, C; Khadangi, F; Rojas-Ruiz, A; Tremblay-Pitre, S | 1 |
| Arnold, LA; Emala, CW; Perez-Zoghbi, JF; Sajorda, DR; Webb, DA; Yocum, GT | 1 |
| Ciotkowska, A; Hennenberg, M; Huang, R; Kolben, T; Ledderose, S; Liu, Y; Magistro, G; Rutz, B; Schulz, H; Springer, F; Stief, CG; Tamalunas, A; Vigodski, V; Wang, R; Wendt, A | 1 |
| Ijpma, G; Lauzon, AM | 1 |
| Cheng, LH; Chou, YL; Liu, SC; Wang, HW; Wang, YT | 1 |
| Azimi, S; Hall, IP; Henry, AP; Kotlikoff, MI; Lee, FK; Lee, JC; Liu, B; Miller, S; Probert, K; Sayers, I | 1 |
| Danielsson, J; Emala, CW; Gallos, G; Kuforiji, AS; Xu, D; Yocum, GT; Zhang, Y | 1 |
| Emala, CW; Heras, AF; Perez-Zoghbi, J; Silver, RB; Veerappan, A; Worgall, S; Worgall, TS | 1 |
| Aronsson, P; Aydogdu, O; Carlsson, T; Gocun, PU; Winder, M | 1 |
| Calco, GN; Nie, Z; Proskocil, BJ | 1 |
| Chen, J; ElMallah, MK; Lifshitz, LM; Liu, Z; Lu, P; Wu, C; ZhuGe, R | 1 |
| Chen, J; Choi, CH; Emala, CW; Fu, XW; Sanderson, MJ; Townsend, EA; Xu, D; Yocum, GT; Zhang, Y | 1 |
| Bellvé, K; Byrne, BJ; ElMallah, MK; Fuller, DD; Keeler, AM; Liu, D; Salemi, J; Xiong, L; ZhuGe, R; Zieger, M | 1 |
| Bossé, Y; Flamand, N; Lortie, K; Mailhot-Larouche, S; Marsolais, D | 1 |
| Boskabady, MH; Emami, B; Ghorani, V; Shakeri, F | 1 |
| Boskabady, MH; Eftekhar, N; Moghimi, A | 1 |
| Gustin, P; Lv, Y; Yang, Q; Yu, Z; Zhang, W; Zhao, S; Zhi, J | 1 |
| Eftekhar, N; Hossein Boskabady, M; Kaveh, M; Moghimi, A; Shakeri, F | 1 |
| Benedetti, A; Ijpma, G; Kachmar, L; Lauzon, AM; Lavoie, JP; Liang, CQ; Panariti, A | 1 |
| Bossé, Y; Mailhot-Larouche, S | 1 |
| Benedetti, A; Ijpma, G; Kachmar, L; Lauzon, AM; Martin, JG; Matusovsky, OS; Panariti, A | 1 |
| Kaminuma, O; Kitamura, N; Kouyama, S; Mori, A; Otomo-Abe, A | 1 |
| Aronsson, P; Carlsson, T; Tobin, G; Winder, M | 2 |
| Bayrami, G; Boskabady, MH; Farkhondeh, T; Jalali, S | 1 |
| Bossé, Y; Couture, C; Lee-Gosselin, A; Paré, PD; Pascoe, CD | 1 |
| Killi, UK; Kuca, K; Soukup, O; Tobin, G; Winder, M; Wsol, V | 1 |
| Aronsson, P; Johnsson, M; Tayem, Y; Tobin, G; Vesela, R; Winder, M; Wsol, V | 1 |
| Anderson, JE; Basu, S; Halayko, AJ; Mitchell, RW; Sharma, P; Stelmack, GL | 1 |
| Chu, YH; Kao, CH; Liu, SC; Wang, HW; Wu, CC | 1 |
| Blanchet, MR; Bossé, Y; Gendron, D; Lee-Gosselin, A; Marsolais, D | 1 |
| Bourke, JE; Donovan, C; Royce, SG; Seow, HJ; Vlahos, R | 1 |
| Bates, JH; Benedetti, A; Ijpma, G; Kachmar, L; Lauzon, AM; Martin, JG; Matusovsky, OS | 1 |
| Aronsson, P; Bergquist, F; Carlsson, T; Mitra, R; Tobin, G; Winder, M | 1 |
| Aggarwal, S; Creighton, J; Doran, SF; Emala, CW; Garantziotis, S; Komarova, S; Lazrak, A; Matalon, S; Stober, VP; Trempus, CS; Yu, Z | 1 |
| Chang, HC; Chen, SY; Cherng, YG; Huang, YF; Liu, FL; Wang, HW | 1 |
| Bates, G; Benedetti, A; Ijpma, G; Kachmar, L; Lauzon, AM; Lavoie, JP; Matusovsky, OS; Zitouni, N | 1 |
| Bossé, Y; Couture, C; Fredberg, JJ; Gazzola, M; Henry, C; King, GG; Marsolais, D | 1 |
| Chen, J; Sanderson, MJ | 1 |
| Chao, PZ; Lee, FP; Liu, SC; Wang, HW | 1 |
| Hasegawa, Y; Ito, S; Kamiya, K; Kondo, M; Kume, H; Makino, Y; Shiraki, A | 1 |
| Dekkers, BG; Meurs, H; Schaafsma, D; Tran, T; Zaagsma, J | 1 |
| Fedan, JS; Ismailoglu, UB; Scott, MR | 1 |
| Ki, SH; Kim, SG; Kim, YM; Lee, CH; Lee, SJ; Lee, WH | 1 |
| Bai, Y; Edelmann, M; Sanderson, MJ | 1 |
| Breithaupt-Faloppa, AC; de Oliveira, AP; Domingos, HV; Lino-dos-Santos-Franco, A; Oliveira-Filho, RM; Shia, MK; Tavares-de-Lima, W; Vargaftig, BB | 1 |
| Oldenburg, PJ; Sisson, JH; Wyatt, TA | 1 |
| Cooper, PR; Damera, G; FitzGerald, GA; Haczku, A; Hui, Y; Jester, WF; Jiang, M; Lawson, JA; Panettieri, RA; Tate, JC; Wang, M; Yao, Y; Zhao, H | 1 |
| Chou, YL; Chu, YH; Wang, HW | 1 |
| Gosens, R; Häberlein, H; Meurs, H; Wolf, A | 1 |
| Bao, MJ; Cao, R; Chen, XP; Deng, WD; Dong, XW; Jiang, JX; Jin, F; Li, FF; Xie, QM; Xie, YC; Zhu, Y | 1 |
| Amery, S; Boskabady, MH; Khakzad, MR; Vahedi, N | 1 |
| Gozzard, N; Makwana, R; Page, C; Spina, D | 1 |
| Anas, Y; Arsito, PN; Nugroho, AE; Riyanto, S; Sukari, MA; Wibowo, JT | 1 |
| Boriek, AM; Moore, J; Schwartz, RJ; Shardonofsky, FR | 1 |
| Cheng, LH; Chu, YH; Kao, CH; Wang, CH; Wang, HW; Wang, JY | 1 |
| Atabai, K; Bernstein, X; Chen, C; Engler, MB; Huang, KE; Huang, X; Kudo, M; Li, JT; Melton, AC; Ren, X; Sheppard, D; Wang, Y | 1 |
| Bolonheis, SM; Damazo, AS; Farsky, SH; Lino-Dos-Santos-Franco, A; Nakasato, A; Shimada, AL; Tavares-de-Lima, W | 1 |
| Bates, JH; Ma, B; Sanderson, M | 1 |
| Botha, CJ; Gehring, R; Van Rooyen, JM; Venter, D | 1 |
| Dey, RD; Fedan, JS; Satterfield, BE; Wu, ZX | 1 |
| Broadley, KJ; Martin, TJ | 1 |
| Ito, S; Ito, Y; Kume, H; Sudo, Y; Takagi, K; Yamaki, K | 1 |
| Anivarro, I; Bayés-Genís, A; Bis, J; Cinca, J; de la Torre, J; Rodríguez-Sinovas, A | 1 |
| Conti, M; Jin, SL; Law, E; Méhats, C; Umetsu, DT; Wahlstrom, J | 1 |
| Gosens, R; Grootte Bromhaar, MM; Hiemstra, M; Meurs, H; Nelemans, SA; Zaagsma, J | 1 |
| Gosens, R; Meurs, H; Nelemans, SA; Schaafsma, D; Zaagsma, J | 1 |
| Bromhaar, MM; Gosens, R; Meurs, H; Nelemans, SA; Schaafsma, D; Tonkes, A; Zaagsma, J | 1 |
| Cocks, TM; Moffatt, JD; Page, CP | 1 |
| Ma, S; Pennefather, JN; Story, ME | 1 |
| Colasurdo, GN; Dakhama, A; Fratelli, C; Larsen, GL; Loader, J; Nguyen, DD | 1 |
| Nelemans, SA; Obels, PP; Oostendorp, J; Terpstra, AR; Zaagsma, J | 1 |
| Lefebvre, RA; Robberecht, P; Vanneste, G | 1 |
| Ali, S; Osborne, RH; Watson, MS | 1 |
| Chen, Z; Gao, Y; Lai, XY; Lu, YB | 1 |
| Boterman, M; Elzinga, CR; Eppens, PB; Meurs, H; Wagemakers, D; Zaagsma, J | 1 |
| Aslani, MR; Boskabady, MH; Tabatabaei, A | 1 |
| Bonacci, JV; Fernandes, DJ; Quan, L; Stewart, AG; Taylor, CC; Ward, JE | 1 |
| Boterman, M; de Jong, AM; Hovens, I; Meurs, H; Nelemans, SA; Penninks, JM; Schaafsma, D; Zaagsma, J | 1 |
| Honjo, H; Ito, S; Kamiya, K; Kodama, I; Kume, H; Oguma, T; Shimokata, K; Takeda, N | 1 |
| Meurs, H; Nelemans, SA; Schaafsma, D; Zaagsma, J; Zuidhof, AB | 1 |
| Bai, Y; Sanderson, MJ | 1 |
| Chen, B; Dowell, M; Fredberg, JJ; Lakser, O; Liu, G; Mitchell, RW; Pinto, LH; Shardonofsky, F; Solway, J | 1 |
| Brusasco, V; Ciacco, C; Crosa, F; Guglielmo, M; Gulotta, C; Hyatt, RE; Pellegrino, R; Perboni, A; Torchio, R; Zerbini, M | 1 |
| Birolini, D; de Arruda, MJ; Fontes, B; Poggetti, RS; Souza, AL; Younes, RN | 1 |
| Drenjancevic-Peric, I; Friesema, J; Lombard, JH; McEwen, S; Roman, RJ; Schulta, D; Yu, M; Zhu, J | 1 |
| Folz, RJ; Liu, JQ; Yang, D | 1 |
| Azoulay, E; Gil, FR; Lauzon, AM; Maghni, K; Zitouni, NB | 1 |
| Bai, Y; Sanderson, MJ; Zhang, M | 1 |
| Brusasco, V; Coletta, G; Dutto, L; Meinero, M; Milanese, M; Nova, G; Pellegrino, R; Sciolla, A | 1 |
| Sarna, SK | 1 |
| Bates, JH; Haverkamp, HC; Irvin, CG; Norton, RJ; Sullivan, MJ; Thompson-Figueroa, JA; Wagers, SS | 1 |
| Ito, S; Ito, Y; Kondo, M; Kume, H; Naruse, K; Oguma, T; Shimokata, K; Suki, B | 1 |
| Lotriet, CJ; Oliver, DW; Venter, DP | 1 |
| Card, JW; Carey, MA; DeGraff, LM; Ferguson, CD; Morgan, DL; Peddada, SD; Voltz, JW; Zeldin, DC | 1 |
| Bates, JH; Lauzon, AM | 1 |
| Chiappetta, CL; Colasurdo, GN; Collins, RA; Gualano, RC; Hantos, Z; Sly, PD; Turner, DJ; Zosky, GR | 1 |
| Dekkers, BG; Meurs, H; Nelemans, SA; Schaafsma, D; Zaagsma, J | 1 |
| Bertin, N; Demoulin, B; Leblanc, AL; Marchal, F; Schweitzer, C | 1 |
| Jo, T; Martin, JG | 1 |
| Gunst, SJ; Liu, Y; Tepper, RS; Xue, Z; Zhang, L | 1 |
| Kaminuma, O; Kitamura, N; Kobayashi, N; Mori, A | 1 |
| Grunstein, MM; Tanaka, DT | 1 |
| Foster, A; Schellenberg, RR | 1 |
| Bartha, C; Minker, E | 1 |
| Blancquaert, JP; Bogaert, MG; Lefebvre, RA; Willems, JL | 1 |
| Andersen, RA; Bøler, JB; Mikalsen, A | 1 |
| Bogaert, MG; Lefebvre, RA; Verplanken, PA | 1 |
| Bank, CM; van der Heijden, PJ; van der Schaar, MW; Zaagsma, J | 1 |
| Cheng, JB; Townley, RG | 2 |
| Mayer, SE; Rietow, MG; Rinard, GA; Torphy, TJ | 1 |
| Butler, J; Downes, H; Hanifin, JM; Hirshman, CA; Peters, J | 1 |
| Brunet, G; Ford-Hutchinson, AW; Hamel, R; Holme, G; Piechuta, H | 1 |
| Bogaert, M; Lefebvre, R; Willems, J | 1 |
| Peach, MJ; Saye, JA; Singer, HA | 1 |
| Barcelon-Yang, C; Brown, BS; Matier, WL; Reynolds, RD; Stout, DM | 1 |
| Lefebvre, R | 1 |
| Raeburn, D; Roberts, JA; Rodger, IW; Thomson, NC | 2 |
| Ekström, J; Malmberg, L | 3 |
| Chiu-Wei, YF; Kasuya, Y; Watanabe, M | 1 |
| Armour, CL; Berend, N; Black, JL; Woolcock, AJ | 1 |
| Peach, MJ; Singer, HA | 1 |
| Cheng, JB | 1 |
| Higuchi, M; Miyamoto, Y; Sakanashi, M; Takeo, S | 1 |
| Abreu, LC; Picarelli, ZP; Valle, JR; Valle, RM | 1 |
| Alderman, B; Leff, AR; Munoz, NM | 1 |
| Goldie, RG; Paterson, JW; Wale, JL | 1 |
| Dirksen, R; Lammers, JW; Nagtegaal, JE; Rodrigues de Miranda, JF; Russel, FG; Siero, HL | 1 |
| Gomi, Y; Mizuno, K; Suzuki, N | 1 |
| Lefebvre, RA; Smits, GJ | 1 |
| Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Cantabrana, B; Hidalgo, A; Pérez Vallina, JR | 1 |
| Elzinga, CR; Meurs, H; Roffel, AF; Zaagsma, J | 1 |
| Heisler, S; Jia, Y; Martin, JG; Xu, L | 1 |
| Ashton, MJ; Foster, M; Karlsson, JA; Maslen, C; Palfreyman, MN; Raeburn, D; Souness, JE; Webber, S | 1 |
| Bai, TR; Bramley, AM | 1 |
| Bloom, JW; Halonen, M; Lai, J; Palmer, JD; Witt-Enderby, PA; Yamamura, HI | 1 |
| Bray, W; Doerschuk, CM; Gunst, SJ; Shen, X; Tepper, RS | 1 |
| Hillman, D; James, A; Pearce-Pinto, G | 1 |
| Bast, A; Hooijerink, H; Huf, FA; Schilt, R; Zuiderveld, OP | 1 |
| Clayton, RA; McGrath, JC; Nally, JE; Thomson, NC | 1 |
| García, P; García-Sacristán, A; Hernández, M; Ordaz, E; Prieto, D; Rivera, L; Símonsen, U | 1 |
| Eltze, M; Galvan, M | 1 |
| Diamond, J; Langlands, JM | 2 |
| Baranowski, SL; Hamann, KJ; Leff, AR; Munoz, NM; Strek, ME; Vita, A; White, SR; Williams, FS | 1 |
| Cattarossi, L; Ernsberger, P; Haxhiu, MA; Haxhiu-Poskurica, B; Martin, RJ; Miller, MJ | 1 |
| Belt, JJ; Fedan, JS; Frazer, DG; Yuan, LX | 1 |
| Black, C; Curry, C; Emala, C; Hirshman, CA; Levine, MA | 1 |
| Karlsson, JA; Raeburn, D; Tomkinson, A | 1 |
| Brusasco, V; Pellegrino, R; Violante, B | 1 |
| Folkerts, G; Hashjin, GS; Henricks, PA; Nijkamp, FP | 1 |
| Boyle, JP; Challiss, RA; Ellis, KE; Mistry, R | 1 |
| Campbell, WB; Pratt, PF; Rosolowsky, M | 1 |
| Gerthoffer, WT | 1 |
| Elzinga, CR; Hoiting, BH; Kuipers, R; Meurs, H; Schuiling, M; Zaagsma, J | 1 |
| Jouët, P; Sarna, SK | 1 |
| Raeburn, D; Tomkinson, A | 1 |
| Kam, KL; Pfaffendorf, M; van Zwieten, PA | 1 |
| Abebe, W; Agrawal, DK; Joshi, S | 1 |
| Fernandes, LB; Goldie, RG; Henry, PJ; Knott, PG; McWilliam, AS; Rigby, PJ | 1 |
| Jia, Y; Martin, JG; Turner, DJ; Xu, L | 1 |
| Du, T; Martin, JG; Opazo Saez, A; Wang, NS | 1 |
| Bottone, AE; Coers, W; de Boer, J; Koopal, M; Meurs, H; Timens, W; Visser, AC; Zaagsma, J | 1 |
| Hüsken, BC; Pfaffendorf, M; Timmenga, EJ; Van Zwieten, PA; Vroom, MB | 1 |
| Colasurdo, GN; Fan, LL; Gelfand, AS; Graves, JP; Larsen, GL; Loader, JE | 1 |
| Jacobs, MJ; Klopper, PJ; Kromhout, JG; Pfaffendorf, M; Van Gulik, TM; Van Marle, J; Vischjager, M | 1 |
| Breukink, HJ; Hajer, R; Henricks, PA; Nijkamp, FP; van der Meer van Roomen, WA; van Nieuwstadt, RA | 1 |
| Dandurand, R; Eidelman, D; Minshall, E; Wang, CG | 1 |
| Schultz, HD; Toews, ML; Ustinova, EE | 1 |
| De Sanctis, GT; Drazen, JM; Huang, PL; Jiao, A; Kobzik, L; Mehta, S; Yandava, C | 1 |
| Olszewski, MA; Robinson, NE; Zhang, XY; Zhu, FX | 1 |
| Ingenito, EP; Suki, B; Yuan, H | 1 |
| Gelfand, EW; Haczku, A; Hamelmann, E; Irvin, C; Joetham, A; Kikutani, H; Loader, J; Oshiba, A; Takeda, K | 1 |
| Campbell, WB; Deinhart, DD; Pfister, SL | 1 |
| Colasurdo, GN; Gelfand, AS; Hemming, VG; Larsen, GL; Loader, JE; Prince, GA | 1 |
| Bast, A; den Hartog, GJ; van Bree, L; van Hoof, HJ; Voss, HP | 1 |
| Du Plooy, WJ; Kahler, CP | 1 |
| Armour, CL; Black, JL; Johnson, PR; Mc Parland, BE | 1 |
| Harrison, S; Page, CP; Paul, W; Perez, AC; Spina, D | 1 |
| Bates, JH; Lavoie, JP; Martin, JG; Shinozuka, N | 1 |
| Dey, RD; Fedan, JS; Maize, DF | 1 |
| Kume, H; Takagi, K | 1 |
| Bard, M; Blanc, FX; Coirault, C; Dartevelle, P; Dulmet, E; Fadel, E; Lecarpentier, Y; Salmeron, S | 1 |
| Chang, VC; Cutler, D; Fedan, JS; Pettit, LL; Viola, JO; Yuan, LX | 1 |
| Chen, JS; Tian, J; Wei, EQ; Zhang, WP | 1 |
| Aziz, I; Lipworth, BJ | 1 |
| Maggi, CA; Renzetti, AR; Santicioli, P; Zagorodnyuk, V | 1 |
| Cowles, VE; Ryan, RP; Sarna, SK | 1 |
| Clayton, RA; MacLean, MR; McGrath, JC; Nally, JE; Thomson, NC | 1 |
| Al-Humadi, NH; Fedan, JS; Hubbs, AF; Millecchia, LL; Nelson, ER; Robinson, VA; Siegel, PD | 1 |
| Asti, C; Bertini, R; Brandolini, L; Caselli, GF; Chiusaroli, R; Intilangelo, A; Pellegrini, L; Ruggieri, V | 1 |
| Gonzalez, A; Ryan, RP; Sarna, SK | 1 |
| Ishii, K; Kubota, Y; Moriuchi, H; Nakahara, T; Sakamato, K; Shigenobu, K; Tanaka, Y; Yunoki, M | 2 |
| Brown, RH; Mitzner, W | 1 |
| Daitoku, K; Iwasa, A; Motomura, S; Sasaki, S | 1 |
| Fisher, SJ; Gandley, RE; Genbacev, O; Gratton, RJ; McCarthy, JF; McLaughlin, MK | 1 |
| Walker, CR; Wilson, BW | 1 |
| De Vries, B; Kooistra, JM; Meurs, H; Roffel, AF; Zaagsma, J | 1 |
| Cutler, D; Fedan, JS | 1 |
| Erbelding, D; Kilbinger, H; Mang, CF | 1 |
| Ito, S; Ito, Y; Kume, H; Yamaki, K | 1 |
| de Vries, B; Meurs, H; Roffel, AF; Zaagsma, J | 1 |
| Chen, Z; Lu, YB; Wu, M | 1 |
| Hayashi, H; Honjo, H; Ito, S; Katoh, H; Kodama, I; Kume, H; Yamaki, K | 1 |
| Guido, P; Salerno, FG; Spanevello, A | 1 |
| Bast, A; van der Poel, KI; van der Vliet, A | 1 |
| Boyle, JP; Kotlikoff, MI; Tomasic, M; Worley, JF | 1 |
| De Vriese, A; Lefebvre, RA; Smits, GJ | 1 |
| Morrison, KJ; Vanhoutte, PM | 1 |
| Bonta, IL; de Jongste, JC; Hulsmann, AR; Kerrebijn, KF; Raatgeep, HR; Stijnen, T | 1 |
| Blosser, S; Mitzner, W; Wagner, E; Yager, D | 1 |
| Bloom, JW; Halonen, M; Mahesh, VK; Nunan, LM; Palmer, JD; Yamamura, HI | 1 |
| Webber, SE; Widdicombe, JG; Woods, AJ; Yurdakos, E | 1 |
| Brusasco, V; Crimi, E; Pellegrino, R; Violante, B | 1 |
| Altes, U; Beinhauer, C; Bognar, IT; Fuder, H; Kessler, I | 1 |
| Bast, A; Brozius, MM; Jansen, W; Leurs, R; Smit, MJ; Timmerman, H | 1 |
| Bast, A; Van der Aar, EM; Van der Vliet, A | 1 |
| Bonta, I; De Jongste, J; Jongejan, R; Kerrebijn, K; Raatgeep, R; Stijnen, T | 1 |
| Arm, JP; Christie, P; Crea, AE; Hawksworth, RJ; Jacques, C; Lee, TH; O'Hickey, SP; Spur, BW | 1 |
| Lin, PJ; Pearson, PJ; Schaff, HV | 1 |
| Bast, A; Doelman, CJ; Oosterom, WC | 1 |
| Fujiwara, I; Hatano, N; Honda, Y; Kurokawa, M; Mastumoto, J; Naruto, S; Sato, F; Uno, H; Yoshida, T | 1 |
| Blaxall, HS; Cunningham, J; Gardier, RW; Killian, LN | 1 |
| Carlo, WA; DiFiore, JM; Haxhiu, MA; Haxhiu-Poskurica, B; Martin, RJ; Miller, MJ | 1 |
| De Jongste, JC; Jongejan, RC; Kerrebijn, KF | 1 |
| Ludwig, MS; Romero, PV | 1 |
| Gomi, Y; Suzuki, N | 1 |
| Gerthoffer, WT; Merkel, L; Torphy, TJ | 1 |
| Bonta, IL; De Jongste, JC; Jongejan, RC; Kerrebijn, KF; Raatgeep, RC | 1 |
| Adachi, M; Kobayashi, H; Misawa, M; Okazawa, A; Takahashi, T | 1 |
| Ajao, P; Britton, JR; Knox, AJ; Tattersfield, AE | 1 |
| Brouwer, F; Meurs, H; Ten Berge, RE; Van Amsterdam, RG; Veninga, NC; Zaagsma, J | 1 |
| Bonta, IL; de Jongste, JC; Jongejan, RC; Kerrebijn, KF; Raatgeep, RC; Stijnen, T | 1 |
| Inagaki, O; Kasuya, Y; Suzuki, N | 1 |
| Coutts, S; Gordon, R; Jolly, S; Khandwala, A; Sonnino, P; Van Inwegen, RG | 1 |
| Angus, JA; Campbell, GR; Cocks, TM; Manderson, JA; Mosse, PR | 1 |
| Miller, LG; Raeburn, D; Summer, WR | 1 |
| Elzinga, CR; Kauffman, HF; Meurs, H; Postema, JB; Roffel, AF; Timmermans, A; Zaagsma, J | 1 |
| de Lanerolle, P; Obara, K; Ruegg, JC; Takai, A | 1 |
| Low, JE; Wright, CD | 1 |
| Cragoe, EJ; Doktor, HS; Ritter, JM | 1 |
| Leff, AR; Munoz, NM; Shioya, T | 1 |
| Hay, DW; Muccitelli, RM; Torphy, TJ; Tucker, SS; Wasserman, MA | 1 |
| Brown, JK; Madison, JM | 1 |
| Barnes, PJ; Löfdahl, CG | 1 |
| Abel, PW; Johnson, RD; Martin, TJ; Minneman, KP | 1 |
| Jensen, AD; Mayer, SE; Puckett, AM; Rinard, GA; Torphy, TJ | 1 |
| Webber, SE; Widdicombe, JG | 1 |
| de Jongste, JC; Kerrebijn, KF; Mons, H; Sterk, PJ; Timmers, MC; Willems, LN | 1 |
| Gunst, SJ; Hyatt, RE; Warner, DO; Wilson, TA | 1 |
| Bellofiore, S; Di Maria, GU; Martin, JG; Mistretta, A | 1 |
| James, AL; Paré, PD | 1 |
| Bonta, IL; de Jongste, JC; Kerrebijn, KF; Mons, H; van Strik, R | 1 |
| Bast, A; Doelman, CJ; Kramer, K; Timmerman, H | 1 |
| Ryden, EB; Walsh, CT | 1 |
| Okayama, H; Sasaki, H; Sasaki, T; Shimura, S; Takishima, T | 1 |
| Bonta, IL; de Jongste, JC; Kerrebijn, KF; Mons, H | 1 |
| Leff, AR; Munoz, NM; Pollack, ER; Shioya, T | 1 |
| Cahill, JF; Fedan, JS; Franczak, MS; Kosten, CJ; Morey, P; Weber, KC | 1 |
| Snashall, PD | 1 |
| Austin, DR; Downes, H; Hirshman, CA; Parks, CM | 1 |
| Ekström, J; Malmberg, L; Wallin, A | 2 |
| Sasaki, H; Sasaki, T; Shimura, S; Takishima, T | 1 |
| Fedan, JS; Hay, DW; Raeburn, D; Rodger, IW | 1 |
| Cahill, JF; Fedan, JS; Franczak, MS; Kosten, CJ; Morey, PR; Weber, KC | 1 |
| Abel, PW; Moore, DH; Puckett, AM; Rinard, GA; Walter, JB | 1 |
| Farmer, SG; Fedan, JS; Fleming, WW; Hay, DW; Raeburn, D | 1 |
| Ekström, J; Malmberg, L; Oberg, S | 1 |
| Collins, SM; Crankshaw, DJ | 1 |
| Hargreave, FE; Kirby, JG; O'Byrne, PM; Ramsdale, EH | 1 |
| Maggi, CA; Meli, A; Subissi, A | 1 |
| Hogg, JC; McLean, TM; Moreno, RH; Paré, PD | 1 |
| Ishii, K; Kato, R | 1 |
| Leff, AR; Mack, M; Munoz, NM; Shioya, T; Solway, J | 1 |
| Armour, CL; Hogg, JC; Paré, PD; Schellenberg, RR; Taylor, SM | 1 |
| Barlow, RB; Weston-Smith, P | 1 |
| Janssen, PA; Reyntjens, AJ; Schuurkes, JA; Van Daele, PG; Van Nueten, JM | 1 |
| Breuing, EP; Kobashi, YL; Markus, RP | 1 |
| Adams, GK; Kleeberger, SR; Spannhake, EW; Wagner, EM | 1 |
| Kasuya, Y; Ono, K; Shigenobu, K | 1 |
6 review(s) available for methacholine chloride and Muscle Contraction
| Article | Year |
|---|---|
Genetic differences in airway smooth muscle function.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Contractile Proteins; Genetic Predisposition to Disease; Humans; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth | 2008 |
Tidal breathing affects airway responsiveness to methacholine.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Humans; Inflammation; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Tidal Volume | 2001 |
Sulphidopeptide leukotrienes in asthma.
Topics: Animals; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Guinea Pigs; Histamine; Humans; Leukotriene E4; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; SRS-A; Trachea | 1991 |
Calcium, calcium channel blockade and airways function.
Topics: Adrenergic beta-Agonists; Allergens; Angina Pectoris; Animals; Asthma; Bronchi; Calcium; Calcium Channel Blockers; Cold Temperature; Drug Interactions; Histamine; Humans; Hypertension; In Vitro Techniques; Mast Cells; Methacholine Chloride; Methacholine Compounds; Mucus; Muscle Contraction; Muscle, Smooth; Physical Exertion; Respiratory Physiological Phenomena; Respiratory System | 1986 |
In-vivo and in-vitro responsiveness of bronchial smooth muscle.
Topics: Airway Resistance; Albuterol; Animals; Asthma; Atropine; Atropine Derivatives; Bronchi; Carbachol; Dose-Response Relationship, Drug; Histamine; Humans; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Serotonin; Trachea | 1986 |
Asthma and the role of inflammation.
Topics: Airway Resistance; Asthma; Humans; Inflammation; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Occupational Diseases; Seasons | 1986 |
2 trial(s) available for methacholine chloride and Muscle Contraction
| Article | Year |
|---|---|
Mechanical response to methacholine and deep inspiration in supine men.
Topics: Adult; Airway Resistance; Bronchoconstriction; Bronchoconstrictor Agents; Elasticity; Humans; Inhalation; Male; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle, Smooth; Respiratory Function Tests; Respiratory Mechanics; Supine Position; Total Lung Capacity | 2007 |
In vivo effect of albuterol on methacholine-contracted bronchi in conjunction with salmeterol and formoterol.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Arginine; Bronchi; Bronchial Provocation Tests; Bronchodilator Agents; Ethanolamines; Female; Forced Expiratory Volume; Formoterol Fumarate; Genotype; Glutamic Acid; Glutamine; Glycine; Homozygote; Humans; Male; Methacholine Chloride; Middle Aged; Muscle Contraction; Polymorphism, Genetic; Salmeterol Xinafoate; Spirometry | 1999 |
282 other study(ies) available for methacholine chloride and Muscle Contraction
| Article | Year |
|---|---|
Synthesis of pyridinium analogues of acetylcholine and their interactions with intestinal muscarinic receptors.
Topics: Acetylcholine; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Pyridinium Compounds; Receptors, Cholinergic; Receptors, Muscarinic | 1979 |
Effects of airway smooth muscle contraction and inflammation on lung tissue compliance.
Topics: Airway Resistance; Animals; Inflammation; Lipopolysaccharides; Lung; Lung Compliance; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Muscle Contraction; Respiratory Mechanics | 2022 |
Inhibition of Full Smooth Muscle Contraction in Isolated Human Detrusor Tissues by Mirabegron Is Limited to Off-Target Inhibition of Neurogenic Contractions.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetanilides; Carbachol; Endothelin-1; Female; Humans; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Receptors, Adrenergic; Thiazoles; Urinary Bladder, Overactive | 2022 |
In mice of both sexes, repeated contractions of smooth muscle in vivo greatly enhance the response of peripheral airways to methacholine.
Topics: Animals; Female; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Trachea | 2022 |
Imidazobenzodiazepine PI320 Relaxes Mouse Peripheral Airways by Inhibiting Calcium Mobilization.
Topics: Animals; Asthma; Calcium; Calcium Signaling; Flumazenil; gamma-Aminobutyric Acid; Inositol; Ligands; Lung; Methacholine Chloride; Mice; Muscle Contraction; Muscle, Smooth; Picrotoxin | 2022 |
Permixon®, hexane-extracted Serenoa repens, inhibits human prostate and bladder smooth muscle contraction and exerts growth-related functions in human prostate stromal cells.
Topics: Actins; Adrenergic Agents; Endothelin-1; Hexanes; Humans; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Phalloidine; Plant Extracts; Prostate; Prostatic Hyperplasia; Serenoa; Sincalide; Stromal Cells; Thromboxanes; Urinary Bladder | 2022 |
Automated, high temporal resolution mechanics measurements during incubation of contractile tissues.
Topics: Animals; Carbon Dioxide; Cells, Cultured; Horses; Methacholine Chloride; Muscle Contraction; Muscle, Smooth | 2023 |
Efficacy of levocetirizine in isolated rat tracheal smooth muscle.
Topics: Animals; Cetirizine; Humans; Menthol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Rats; Trachea | 2023 |
Exposure to lipopolysaccharide (LPS) reduces contractile response of small airways from GSTCD-/- mice.
Topics: Animals; Bronchioles; Disease Models, Animal; Female; Gene Knockout Techniques; Glutathione Transferase; Lipopolysaccharides; Male; Methacholine Chloride; Mice; Muscle Contraction; Tumor Necrosis Factor-alpha; Up-Regulation | 2019 |
Agonism of the TMEM16A calcium-activated chloride channel modulates airway smooth muscle tone.
Topics: Acetylcholine; Animals; Anoctamin-1; Bronchial Hyperreactivity; Bronchoconstriction; Calcium; Cells, Cultured; Guinea Pigs; Humans; Inositol Phosphates; Lung; Methacholine Chloride; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Neoplasm Proteins; RNA, Messenger | 2020 |
Increasing Sphingolipid Synthesis Alleviates Airway Hyperreactivity.
Topics: Alveolar Epithelial Cells; Bradykinin; Bronchial Hyperreactivity; Calcium; Calcium Signaling; Fenretinide; Glycine; Humans; Hydrazines; Metabolome; Methacholine Chloride; Muscle Contraction; Serine C-Palmitoyltransferase; Sphingolipids | 2020 |
Prostate-to-bladder cross-sensitization in a model of zymosan-induced chronic pelvic pain syndrome in rats.
Topics: Animals; Cholinergic Agonists; Chronic Pain; Inflammation; Lower Urinary Tract Symptoms; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Pelvic Pain; Prostate; Prostatitis; Purinergic Agonists; Rats; Urinary Bladder; Urinary Bladder, Overactive; Urination; Zymosan | 2021 |
Insulin acutely increases agonist-induced airway smooth muscle contraction in humans and rats.
Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Calcium; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Obesity; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Trachea; Vagus Nerve | 2021 |
Genetic deletion of the Tas2r143/Tas2r135/Tas2r126 cluster reveals that TAS2Rs may not mediate bitter tastant-induced bronchodilation.
Topics: Animals; Base Sequence; Gene Deletion; Gene Expression Profiling; Ligands; Methacholine Chloride; Mice, Knockout; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Receptors, G-Protein-Coupled; Respiratory System; Taste; Tongue | 2021 |
Role of transient receptor potential vanilloid 1 in the modulation of airway smooth muscle tone and calcium handling.
Topics: Acetylcholine; Animals; Calcium; Capsaicin; Guinea Pigs; Humans; Immunohistochemistry; Methacholine Chloride; Mice; Muscle Contraction; Muscle, Smooth; RNA, Messenger; Trachea; TRPV Cation Channels | 2017 |
Airway smooth muscle dysfunction in Pompe (
Topics: Albuterol; alpha-Glucosidases; Animals; Bronchi; Calcium Signaling; Extracellular Space; Glycogen; Glycogen Storage Disease Type II; Lung; Methacholine Chloride; Mice; Muscle Contraction; Muscle, Skeletal; Potassium Chloride; Trachea | 2017 |
An in vitro study examining the duration between deep inspirations on the rate of renarrowing.
Topics: Animals; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Parenchymal Tissue; Time Factors | 2017 |
Relaxant effect of Curcuma longa on rat tracheal smooth muscle and its possible mechanisms.
Topics: Animals; Bronchodilator Agents; Curcuma; Dose-Response Relationship, Drug; Ethanol; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Plant Extracts; Plant Roots; Potassium Chloride; Rats; Rats, Wistar; Theophylline; Trachea | 2017 |
Prophylactic effect of rosmarinic acid on tracheal responsiveness, white blood cell count and oxidative stress markers in lung lavage of sensitized rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Bronchoalveolar Lavage Fluid; Cinnamates; Depsides; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Leukocytes; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Ovalbumin; Oxidative Stress; Rats, Wistar; Respiratory Hypersensitivity; Rosmarinic Acid; Trachea | 2018 |
Protective effects of tiotropium alone or combined with budesonide against cadmium inhalation induced acute neutrophilic pulmonary inflammation in rats.
Topics: Acute Disease; Animals; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Budesonide; Cadmium; Cell Count; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Inhalation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methacholine Chloride; Muscle Contraction; Neutrophils; Pneumonia; Rats; Rats, Sprague-Dawley; Tiotropium Bromide | 2018 |
Ocimum basilicum affects tracheal responsiveness, lung inflammatory cells and oxidant-antioxidant biomarkers in sensitized rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Bronchoalveolar Lavage Fluid; Leukocyte Count; Leukocytes; Lung; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Ocimum basilicum; Ovalbumin; Oxidants; Plant Extracts; Rats, Wistar; Respiratory Hypersensitivity; Trachea | 2019 |
Maintenance of contractile function of isolated airway smooth muscle after cryopreservation.
Topics: Animals; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Histamine; Horses; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Trachea | 2018 |
Interval between simulated deep inspirations on the dynamics of airway smooth muscle contraction in guinea pig bronchi.
Topics: Airway Resistance; Animals; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Female; Guinea Pigs; In Vitro Techniques; Inhalation; Isoproterenol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nonlinear Dynamics; Physical Stimulation; Time Factors | 2019 |
Contractile Properties of Intrapulmonary Airway Smooth Muscle in Cystic Fibrosis.
Topics: Adult; Asthma; Bronchoconstrictor Agents; Bronchodilator Agents; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Interleukin-13; Isoproterenol; Male; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Respiratory Hypersensitivity; Respiratory System; Young Adult | 2019 |
A contraction assay system using primary cultured mouse bronchial smooth muscle cells.
Topics: Acetates; Animals; Bronchi; Cells, Cultured; Cyclopropanes; Leukotriene D4; Methacholine Chloride; Mice; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Muscle; Primary Cell Culture; Quinolines; Sulfides | 2013 |
A novel in situ urinary bladder model for studying afferent and efferent mechanisms in the micturition reflex in the rat.
Topics: Adenosine Triphosphate; Afferent Pathways; Animals; Efferent Pathways; Electric Stimulation; Male; Methacholine Chloride; Models, Animal; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reflex; Urinary Bladder; Urination | 2014 |
The effect of lead exposure on tracheal responsiveness to methacholine and ovalbumin, total and differential white blood cells count, and serum levels of immunoglobulin E, histamine, and cytokines in guinea pigs.
Topics: Animals; Blood Cell Count; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Cytokines; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Immunoglobulin E; In Vitro Techniques; Interferon-gamma; Interleukin-4; Lead; Lead Poisoning; Leukocyte Count; Leukocytes; Male; Methacholine Chloride; Muscle Contraction; Ovalbumin; Serine Proteinase Inhibitors; Trachea | 2014 |
Does the length dependency of airway smooth muscle force contribute to airway hyperresponsiveness?
Topics: Acetylcholine; Airway Remodeling; Asthma; Bronchi; Bronchial Hyperreactivity; Humans; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Potassium; Trachea | 2013 |
In vitro functional interactions of acetylcholine esterase inhibitors and muscarinic receptor antagonists in the urinary bladder of the rat.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Diamines; Dose-Response Relationship, Drug; Heart Atria; In Vitro Techniques; Male; Methacholine Chloride; Muscarinic Antagonists; Muscle Contraction; Obidoxime Chloride; Physostigmine; Rats; Receptor Cross-Talk; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2014 |
Cyclophosphamide-induced alterations of the micturition reflex in a novel in situ urinary bladder model in the anesthetized rat.
Topics: Adenosine Triphosphate; Afferent Pathways; Animals; Cyclophosphamide; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Efferent Pathways; Electric Stimulation; Male; Mechanotransduction, Cellular; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Pressure; Rats, Sprague-Dawley; Reflex; Time Factors; Urinary Bladder; Urination | 2015 |
Inhibition of nitric oxide synthase prevents muscarinic and purinergic functional changes and development of cyclophosphamide-induced cystitis in the rat.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cyclophosphamide; Cystitis; Enzyme Inhibitors; Immunohistochemistry; In Vitro Techniques; Male; Mast Cells; Methacholine Chloride; Muscle Contraction; Nitric Oxide Synthase; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Purinergic; Urinary Bladder | 2014 |
Role of dystrophin in airway smooth muscle phenotype, contraction and lung function.
Topics: Animals; Blotting, Western; Cells, Cultured; Dogs; Dystrophin; Immunohistochemistry; Lung; Methacholine Chloride; Mice, Inbred mdx; Mice, Knockout; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Muscle; Myosin Heavy Chains; Phosphatidylinositol 3-Kinases; Respiratory System; Signal Transduction; Trachea | 2014 |
Steroids and antihistamines synergize to inhibit rat's airway smooth muscle contractility.
Topics: Animals; Cetirizine; Cholinergic Agents; Disease Models, Animal; Drug Synergism; Electric Stimulation; Glucocorticoids; Histamine Antagonists; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Prednisolone; Rats; Rhinitis, Allergic; Trachea; Treatment Outcome | 2015 |
The gain of smooth muscle's contractile capacity induced by tone on in vivo airway responsiveness in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Asthma; Bronchodilator Agents; Female; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; Respiratory Hypersensitivity; Respiratory System | 2015 |
Alteration of Airway Reactivity and Reduction of Ryanodine Receptor Expression by Cigarette Smoke in Mice.
Topics: Airway Resistance; Animals; Calcium Signaling; Male; Methacholine Chloride; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Pulmonary Disease, Chronic Obstructive; Ryanodine Receptor Calcium Release Channel; Serotonin; Smoking | 2015 |
Human trachealis and main bronchi smooth muscle are normoresponsive in asthma.
Topics: Adult; Aged; Asthma; Bronchi; Bronchial Hyperreactivity; Female; Humans; Male; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle, Smooth; Trachea; Young Adult | 2015 |
Local Change in Urinary Bladder Contractility Following CNS Dopamine Denervation in the 6-OHDA Rat Model of Parkinson's Disease.
Topics: Adenosine Triphosphate; Animals; Corpus Striatum; Denervation; Disease Models, Animal; Dopaminergic Neurons; Electric Stimulation; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Oxidopamine; Parkinsonian Disorders; Purinergic Agents; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2015 |
Hyaluronan mediates airway hyperresponsiveness in oxidative lung injury.
Topics: Alpha-Globulins; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Chlorine; Enzyme Activation; Extracellular Matrix; Hyaluronic Acid; Inflammation; Lung Injury; Membrane Potentials; Methacholine Chloride; Mice; Mice, Inbred C57BL; Muscle Contraction; Myocytes, Smooth Muscle; Oxidative Stress; Patch-Clamp Techniques; Reactive Oxygen Species; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Trachea | 2015 |
Effects of levobupivacaine on isolated rat tracheal smooth muscle.
Topics: Animals; Bupivacaine; Electric Stimulation; Levobupivacaine; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Rats; Trachea | 2015 |
Peripheral Airway Smooth Muscle, but Not the Trachealis, Is Hypercontractile in an Equine Model of Asthma.
Topics: Actin Cytoskeleton; Animals; Asthma; Blotting, Western; Ca(2+) Mg(2+)-ATPase; Contractile Proteins; Disease Models, Animal; Female; Horse Diseases; Horses; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myofibrils; Myosin Heavy Chains; Myosins; Respiratory Mechanics; Trachea | 2016 |
Smooth muscle in human bronchi is disposed to resist airway distension.
Topics: Aged; Biomechanical Phenomena; Bronchi; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Lung Volume Measurements; Male; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle, Smooth; Neoplasms; Respiration | 2016 |
Store-operated calcium entry is required for sustained contraction and Ca
Topics: Animals; Benzamides; Calcium; Calcium Channel Blockers; Calcium Channels; Female; Lung; Methacholine Chloride; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Nifedipine; Nimodipine; Pyrazoles | 2017 |
Menthol inhibiting parasympathetic function of tracheal smooth muscle.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Menthol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Rats; Trachea | 2016 |
Inhibition by the cold receptor agonists menthol and icilin of airway smooth muscle contraction.
Topics: Animals; Calcium; Cold Temperature; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Intracellular Fluid; Male; Menthol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Pyrimidinones; Spectrometry, Fluorescence; Thermoreceptors; Trachea | 2008 |
Insulin-induced laminin expression promotes a hypercontractile airway smooth muscle phenotype.
Topics: Administration, Inhalation; Animals; Cattle; Chromones; DNA Replication; In Vitro Techniques; Insulin; Isometric Contraction; Laminin; Methacholine Chloride; Mice; Morpholines; Muscle Contraction; Muscle, Smooth; Oligopeptides; Phenotype; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; rho-Associated Kinases; RNA, Messenger; Signal Transduction; Trachea | 2009 |
Effects of cytokines on mechanical and epithelial bioelectric responses to methacholine and hyperosmolarity in guinea-pig airways: an in vitro study.
Topics: Animals; Biomechanical Phenomena; Bronchoconstrictor Agents; Cytokines; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Epithelial Cells; Guinea Pigs; Lipopolysaccharides; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Perfusion; Respiratory Mucosa; Respiratory System; Time Factors; Trachea | 2009 |
Galpha13 regulates methacholine-induced contraction of bronchial smooth muscle via phosphorylation of MLC20.
Topics: Airway Resistance; Animals; Bronchi; Bronchoconstrictor Agents; Calcium; Cells, Cultured; Disease Models, Animal; GTP-Binding Protein alpha Subunits, G12-G13; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Myosin Light Chains; Ovalbumin; Phosphorylation; Respiratory Hypersensitivity; Trachea | 2009 |
The contribution of inositol 1,4,5-trisphosphate and ryanodine receptors to agonist-induced Ca(2+) signaling of airway smooth muscle cells.
Topics: Anesthetics, Local; Animals; Boron Compounds; Bronchoconstriction; Bronchoconstrictor Agents; Calcium; Calcium Signaling; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscle Contraction; Myocytes, Smooth Muscle; Organ Culture Techniques; Permeability; Potassium Chloride; Ryanodine; Ryanodine Receptor Calcium Release Channel; Temperature; Tetracaine | 2009 |
Connective tissue mast cells are the target of formaldehyde to induce tracheal hyperresponsiveness in rats: putative role of leukotriene B4 and nitric oxide.
Topics: Animals; Arginine; Connective Tissue Cells; Formaldehyde; In Vitro Techniques; Leukotriene B4; Male; Mast Cells; Methacholine Chloride; Muscle Contraction; Nitric Oxide; Ovalbumin; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Trachea | 2010 |
Ethanol attenuates contraction of primary cultured rat airway smooth muscle cells.
Topics: Animals; Cell Death; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Ethanol; Methacholine Chloride; Mice; Models, Biological; Muscle Contraction; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; Trachea | 2010 |
Deletion of microsomal prostaglandin E synthase-1 does not alter ozone-induced airway hyper-responsiveness.
Topics: Airway Resistance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbachol; Cell Differentiation; Dinoprostone; Female; Gene Deletion; Intramolecular Oxidoreductases; Methacholine Chloride; Mice; Mice, Knockout; Microsomes; Muscle Contraction; Muscle, Smooth; Ozone; Prostaglandin-E Synthases; Prostaglandins; Respiratory System | 2010 |
Azelastine nasal spray inhibiting parasympathetic function of tracheal smooth muscle.
Topics: Animals; Electric Stimulation; Histamine H1 Antagonists, Non-Sedating; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Phthalazines; Rats; Trachea | 2010 |
Pre-treatment with α-hederin increases β-adrenoceptor mediated relaxation of airway smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Bronchodilator Agents; Cattle; Drug Synergism; Hedera; Histamine; Isoproterenol; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Oleanolic Acid; Plant Extracts; Plant Leaves; Saponins; Trachea | 2011 |
Characterization of bencycloquidium bromide, a novel muscarinic M(3) receptor antagonist in guinea pig airways.
Topics: Animals; Antigens; Atrial Function, Right; Bridged Bicyclo Compounds, Heterocyclic; Bronchoconstriction; Carbachol; CHO Cells; Cricetinae; Cricetulus; Guinea Pigs; Heart Atria; Humans; Ileum; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Receptor, Muscarinic M3; Respiratory System; Trachea; Urinary Bladder | 2011 |
The effect of vitamin E on tracheal responsiveness and lung inflammation in sulfur mustard exposed guinea pigs.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bronchoalveolar Lavage Fluid; Cell Count; Chemical Warfare Agents; Cytokines; Dexamethasone; Drug Therapy, Combination; Female; Guinea Pigs; In Vitro Techniques; Leukocytes; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Mustard Gas; Osmolar Concentration; Pneumonia; Trachea; Vitamin E | 2011 |
TNF-α-induces airway hyperresponsiveness to cholinergic stimulation in guinea pig airways.
Topics: Animals; Blood Pressure; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Electric Stimulation; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Serotonin; Serotonin Receptor Agonists; Trachea; Tumor Necrosis Factor-alpha | 2012 |
Effects of marmin, a compound isolated from Aegle marmelos Correa, on contraction of the guinea pig-isolated trachea.
Topics: Aegle; Animals; Calcium Chloride; Coumarins; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; p-Methoxy-N-methylphenethylamine; Trachea | 2011 |
Airways in smooth muscle α-actin null mice experience a compensatory mechanism that modulates their contractile response.
Topics: Actins; Airway Resistance; Animals; Contractile Proteins; Lung; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Muscle, Smooth; Myocytes, Smooth Muscle; Respiration, Artificial; RNA, Messenger; Smooth Muscle Myosins | 2012 |
Anti-cholinergic effect of singulair on isolated rat's tracheal smooth muscle.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Bronchoconstrictor Agents; Cholinergic Antagonists; Cyclopropanes; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Quinolines; Rats; Sulfides; Trachea | 2012 |
IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction.
Topics: Analysis of Variance; Animals; Asthma; CD11c Antigen; CD4 Antigens; Dendritic Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; In Vitro Techniques; Integrin alphaV; Interleukin-17; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Ovalbumin; Potassium Chloride; Respiratory System; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Th17 Cells | 2012 |
In vivo hydroquinone exposure causes tracheal hyperresponsiveness due to TNF secretion by epithelial cells.
Topics: Animals; Chlorpromazine; Dose-Response Relationship, Drug; Hydroquinones; Male; Mast Cells; Methacholine Chloride; Mice; Muscle Contraction; Respiratory Mucosa; Trachea; Tumor Necrosis Factor-alpha | 2012 |
Airway-parenchymal interdependence in the lung slice.
Topics: Airway Resistance; Animals; Bronchi; Bronchoconstrictor Agents; Elasticity; Lung; Methacholine Chloride; Models, Biological; Muscle Contraction; Organ Culture Techniques; Stress, Mechanical | 2013 |
The effect of three bufadienolide cardiac glycosides on contraction of isolated rat jejunum.
Topics: Animals; Atropine; Bufanolides; Cardiac Glycosides; Cholenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; In Vitro Techniques; Jejunum; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley | 2002 |
Interleukin-1beta-induced airway hyperresponsiveness enhances substance P in intrinsic neurons of ferret airway.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Disease Models, Animal; Electric Stimulation; Ferrets; Instillation, Drug; Interleukin-1; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Neurons; Substance P; Trachea | 2002 |
Contractile responses to adenosine, R-PIA and ovalbumen in passively sensitized guinea-pig isolated airways.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Immune Sera; In Vitro Techniques; Isotonic Solutions; Methacholine Chloride; Muscle Contraction; Ovalbumin; Purinergic P1 Receptor Agonists; Receptor, Adenosine A3; Time Factors; Trachea; Vasodilator Agents | 2002 |
Effects of direct and indirect activation of G protein of adenylyl cyclase on the subsequent response to beta-adrenergic receptor agonists in human trachealis.
Topics: Adrenergic beta-Agonists; Aged; Aged, 80 and over; Bronchoconstrictor Agents; Cholera Toxin; Enzyme Activation; Heterotrimeric GTP-Binding Proteins; Humans; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Trachea | 2002 |
Coronary smooth muscle reactivity to muscarinic stimulation after ischemia-reperfusion in porcine myocardial infarction.
Topics: Animals; Blood Pressure; Bradykinin; Coronary Circulation; Coronary Vessels; Electrocardiography; Endothelium, Vascular; Female; Heart Rate; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Infarction; Pericardium; Reperfusion Injury; Swine; Vasoconstriction; Ventricular Dysfunction, Left | 2003 |
PDE4D plays a critical role in the control of airway smooth muscle contraction.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arginine Vasopressin; Bronchoconstrictor Agents; Carbachol; Cholinergic Agonists; Culture Techniques; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclooxygenase Inhibitors; Dinoprostone; Indomethacin; Isoenzymes; Methacholine Chloride; Mice; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Potassium Chloride; Rolipram; Trachea | 2003 |
Insulin induces a hypercontractile airway smooth muscle phenotype.
Topics: Animals; Cattle; Culture Media, Serum-Free; DNA; Dose-Response Relationship, Drug; Drug Synergism; Epidermal Growth Factor; In Vitro Techniques; Insulin; Insulin-Like Growth Factor I; Isometric Contraction; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Platelet-Derived Growth Factor; Potassium Chloride; Trachea | 2003 |
Role of Rho-kinase in maintaining airway smooth muscle contractile phenotype.
Topics: Animals; Bronchodilator Agents; Cattle; Cell Division; Cells, Cultured; DNA; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Organ Culture Techniques; Phenotype; Potassium Chloride; Protein Serine-Threonine Kinases; rho-Associated Kinases; Tetrazolium Salts; Thiazoles; Thymidine; Trachea | 2004 |
Muscarinic M(3) receptor-dependent regulation of airway smooth muscle contractile phenotype.
Topics: Animals; Calcium; Cattle; Contractile Proteins; Histamine; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Phenotype; Phosphatidylinositol 3-Kinases; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Receptor, Muscarinic M3; Trachea | 2004 |
Role of the epithelium and acetylcholine in mediating the contraction to 5-hydroxytryptamine in the mouse isolated trachea.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Atropine; Boron Compounds; Botulinum Toxins, Type A; Calcium Channel Blockers; Calcium Channels; Cartilage; Electric Stimulation; Epithelial Cells; Epithelium; Female; Ganglia, Parasympathetic; Inositol 1,4,5-Trisphosphate Receptors; Ketanserin; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; omega-Conotoxin GVIA; Receptors, Cytoplasmic and Nuclear; Serotonin; Surface-Active Agents; Tetrodotoxin; Trachea | 2004 |
Muscarinic receptors mediating contraction of female mouse urinary bladder: effects of oestrogen.
Topics: Animals; Atropine; Estrogens; Female; In Vitro Techniques; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Organ Size; Pregnancy; Radioligand Assay; Receptors, Muscarinic; Urinary Bladder; Vagina | 2004 |
Mechanisms determining cholinergic neural responses in airways of young and mature rabbits.
Topics: Acetylcholine; Acetylcholinesterase; Aging; Animals; Autonomic Nervous System; Bronchoconstrictor Agents; Choline O-Acetyltransferase; Electric Stimulation; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nerve Growth Factors; Rabbits; Receptor, Muscarinic M2; Receptors, Cholinergic; Respiratory Mechanics; Substance P; Trachea | 2004 |
Modulation of beta2- and beta3-adrenoceptor-mediated relaxation of rat oesophagus smooth muscle by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Esophagus; Ethanolamines; Fenoterol; Formoterol Fumarate; Indoles; Male; Maleimides; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Netherlands; Phenethylamines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2004 |
Inhibitory pathways in the circular muscle of rat jejunum.
Topics: Adenosine Triphosphate; Animals; Apamin; Autonomic Nervous System; Cyclic GMP; Electric Stimulation; Isometric Contraction; Jejunum; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nerve Growth Factors; Neuropeptides; Neurotransmitter Agents; Nitric Oxide; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Small-Conductance Calcium-Activated Potassium Channels; Synaptic Transmission; Tetrodotoxin; Vasoactive Intestinal Peptide | 2004 |
The stimulant cathartic, emodin, contracts the rat isolated ileum by triggering release of endogenous acetylcholine.
Topics: Acetylcholine; Animals; Atropine; Catecholamines; Cathartics; Dose-Response Relationship, Drug; Emodin; Hemicholinium 3; Ileum; In Vitro Techniques; Male; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neurotransmitter Uptake Inhibitors; Rats; Rats, Wistar | 2004 |
[Inhibition of acetamide-45 on airway smooth muscle contraction induced by electric field stimulation and methacholine in vitro].
Topics: Acetamides; Animals; Depression, Chemical; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Random Allocation; Rats; Rats, Sprague-Dawley; Trachea | 2005 |
Potentiation of beta-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C.
Topics: Adrenergic beta-Agonists; Animals; Cattle; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Histamine; In Vitro Techniques; Indoles; Isoproterenol; Maleimides; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Protein Kinase C; Receptors, Adrenergic, beta; Trachea | 2005 |
Influence of epithelium and isoprenaline incubation on responsiveness of guinea-pig trachea to methacholine.
Topics: Adrenergic beta-Agonists; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Bronchodilator Agents; Epithelium; Guinea Pigs; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Trachea | 2006 |
The PPARgamma ligand, rosiglitazone, reduces airways hyperresponsiveness in a murine model of allergen-induced inflammation.
Topics: Allergens; Animals; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Goblet Cells; Guinea Pigs; Hyperplasia; In Vitro Techniques; Injections, Intraperitoneal; Ligands; Matrix Metalloproteinase 2; Methacholine Chloride; Mice; Mice, Inbred C57BL; Muscle Contraction; Ovalbumin; Pneumonia; PPAR gamma; Respiratory Hypersensitivity; Rosiglitazone; Thiazolidinediones; Time Factors; Trachea; Vasodilator Agents | 2006 |
Differential Rho-kinase dependency of full and partial muscarinic receptor agonists in airway smooth muscle contraction.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Alkylation; Amides; Animals; Bronchoconstrictor Agents; Calcium; Cattle; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Organ Culture Techniques; Pilocarpine; Protein Serine-Threonine Kinases; Pyridines; Receptors, Muscarinic; rho-Associated Kinases; Trachea | 2006 |
Involvement of reduced sensitivity to Ca in beta-adrenergic action on airway smooth muscle.
Topics: Adrenergic beta-Agonists; Amides; Animals; Asthma; Bucladesine; Calcium; Calcium Channel Blockers; Colforsin; Cyclic AMP Receptor Protein; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Fura-2; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Maleimides; Marine Toxins; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Phosphatase; Oxazoles; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Trachea | 2006 |
Inhibition of Rho-kinase normalizes nonspecific hyperresponsiveness in passively sensitized airway smooth muscle preparations.
Topics: Amides; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Histamine; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Ovalbumin; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Time Factors; Trachea | 2006 |
Modulation of the Ca2+ sensitivity of airway smooth muscle cells in murine lung slices.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arterioles; Bronchoconstrictor Agents; Caffeine; Calcium; Central Nervous System Stimulants; Colforsin; Cyclic AMP; Enzyme Inhibitors; In Vitro Techniques; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscle Contraction; Myocytes, Smooth Muscle; Protein Kinase C; Respiratory System; Ryanodine | 2006 |
Tidal breathing pattern differentially antagonizes bronchoconstriction in C57BL/6J vs. A/J mice.
Topics: Airway Obstruction; Animals; Bronchoconstriction; Bronchoconstrictor Agents; Cholinergic Fibers; Female; Hypersensitivity; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Pulmonary Ventilation; Respiratory Mechanics; Respiratory System; Tidal Volume | 2006 |
Effects of chest wall strapping on mechanical response to methacholine in humans.
Topics: Adult; Airway Resistance; Bronchial Provocation Tests; Bronchoconstrictor Agents; Humans; Inhalation; Lung; Lung Volume Measurements; Male; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle, Smooth; Residual Volume; Respiratory Function Tests; Respiratory Mechanics; Thoracic Wall | 2006 |
Intestinal ischemia/reperfusion induces bronchial hyperreactivity and increases serum TNF-alpha in rats.
Topics: Animals; Bronchial Hyperreactivity; Disease Models, Animal; Intestines; Liver; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2006 |
Role of superoxide and angiotensin II suppression in salt-induced changes in endothelial Ca2+ signaling and NO production in rat aorta.
Topics: Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Blood Pressure; Calcium; Calcium Signaling; Cyclic N-Oxides; Endothelium, Vascular; Enzyme Inhibitors; Histamine; In Vitro Techniques; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Spin Labels; Superoxides; Thapsigargin | 2006 |
A novel bronchial ring bioassay for the evaluation of small airway smooth muscle function in mice.
Topics: Animals; Biological Assay; Boron Compounds; Bronchi; Bronchoconstrictor Agents; Calcium Channel Blockers; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Methacholine Chloride; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Papaverine; Potassium Chloride; Respiratory Mucosa; Ryanodine; Stress, Mechanical; Substance P; Vasodilator Agents | 2006 |
Smooth muscle myosin isoform expression and LC20 phosphorylation in innate rat airway hyperresponsiveness.
Topics: Actins; Animals; Blotting, Western; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents; Calmodulin-Binding Proteins; Disease Models, Animal; Isomerism; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myosin Heavy Chains; Myosin Light Chains; Phosphorylation; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; Smooth Muscle Myosins | 2006 |
Contractility and Ca2+ signaling of smooth muscle cells in different generations of mouse airways.
Topics: Animals; Bronchoconstrictor Agents; Calcium Signaling; Cells, Cultured; In Vitro Techniques; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscle Contraction; Myocytes, Smooth Muscle; Potassium Chloride; Receptor, Muscarinic M3; Receptor, Serotonin, 5-HT2A; Serotonin | 2007 |
Enteric descending and afferent neural signaling stimulated by giant migrating contractions: essential contributing factors to visceral pain.
Topics: Afferent Pathways; Animals; Atropine; Calcitonin Gene-Related Peptide; Colic; Dogs; Enteric Nervous System; Female; Gastrointestinal Motility; Heart Rate; Inflammatory Bowel Diseases; Intestine, Small; Irritable Bowel Syndrome; Male; Methacholine Chloride; Muscarinic Antagonists; Muscle Contraction; Myoelectric Complex, Migrating; NG-Nitroarginine Methyl Ester; Nicotinic Agonists; Nitric Oxide Synthase; Purinergic P2 Receptor Antagonists; Receptors, Tachykinin; Serotonin Antagonists; Verapamil | 2007 |
Intrinsic and antigen-induced airway hyperresponsiveness are the result of diverse physiological mechanisms.
Topics: Administration, Inhalation; Animals; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Computer Simulation; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Mathematics; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Muscle Contraction; Muscle, Smooth; Phenotype; Respiratory Hypersensitivity | 2007 |
Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle.
Topics: Amides; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cations; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Gadolinium; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Intracellular Signaling Peptides and Proteins; Ion Channels; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrobenzenes; Protein Serine-Threonine Kinases; Pyrazoles; Pyridines; rho-Associated Kinases; Simvastatin; Stress, Mechanical; Sulfonamides; Trachea | 2006 |
The pharmacological effects of ozone on isolated guinea pig tracheal preparations.
Topics: Animals; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Oxidants, Photochemical; Ozone; Trachea | 2007 |
Male sex hormones promote vagally mediated reflex airway responsiveness to cholinergic stimulation.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Carbachol; Dihydrotestosterone; Female; In Vitro Techniques; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; Respiratory Function Tests; Sex Factors; Trachea; Vagotomy; Vagus Nerve | 2007 |
Parenchymal tethering, airway wall stiffness, and the dynamics of bronchoconstriction.
Topics: Airway Resistance; Animals; Biomechanical Phenomena; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Computer Simulation; Lung; Lung Compliance; Methacholine Chloride; Models, Biological; Muscle Contraction; Muscle, Smooth; Rabbits; Rats; Reproducibility of Results; Tidal Volume; Time Factors | 2007 |
Lack of long-term effects of respiratory syncytial virus infection on airway function in mice.
Topics: Aging; Anesthesia; Animals; Body Weight; Bronchoconstriction; Electric Stimulation; In Vitro Techniques; Lung; Membrane Potentials; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscarinic Agonists; Muscle Contraction; Respiratory Function Tests; Respiratory Mechanics; Respiratory Syncytial Virus Infections; Trachea | 2007 |
Extracellular matrix proteins differentially regulate airway smooth muscle phenotype and function.
Topics: Animals; Bronchoconstrictor Agents; Cattle; Cell Division; Collagen Type I; Extracellular Matrix Proteins; Fibronectins; Laminin; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Organ Culture Techniques; Phenotype; Potassium Chloride; Trachea | 2007 |
Airway response to induced muscular contraction in spontaneously breathing rabbits.
Topics: Adaptation, Physiological; Airway Resistance; Analysis of Variance; Animals; Bronchoconstrictor Agents; Electric Stimulation; Methacholine Chloride; Models, Animal; Muscle Contraction; Physical Exertion; Pulmonary Ventilation; Rabbits; Respiratory Mechanics | 2008 |
Chronic inflation of ferret lungs with CPAP reduces airway smooth muscle contractility in vivo and in vitro.
Topics: Acetylcholine; Administration, Inhalation; Airway Resistance; Animals; Bronchial Provocation Tests; Bronchoconstrictor Agents; Continuous Positive Airway Pressure; Dose-Response Relationship, Drug; Ferrets; Lung; Methacholine Chloride; Muscle Contraction; Muscle Strength; Muscle, Smooth; Myosin Light Chains; Phosphorylation; Stress, Mechanical; Time Factors; Tomography, X-Ray Computed; Trachea | 2008 |
A contraction assay system using established human bronchial smooth muscle cells.
Topics: Animals; Biological Assay; Bronchi; Bronchoconstrictor Agents; Cattle; Cells, Cultured; Collagen; Gels; Histamine; Humans; Methacholine Chloride; Muscle Contraction; Myocytes, Smooth Muscle | 2008 |
Mechanisms of substance P-induced contraction of rabbit airway smooth muscle.
Topics: Animals; Atropine; Biomechanical Phenomena; Dose-Response Relationship, Drug; Ganglia, Parasympathetic; Hemicholinium 3; Hexamethonium; Hexamethonium Compounds; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Neostigmine; Nerve Block; Neural Inhibition; Rabbits; Substance P; Synaptic Transmission; Tetrodotoxin; Trachea | 1984 |
In vitro responses of human asthmatic airway and pulmonary vascular smooth muscle.
Topics: Allergens; Asthma; Bronchi; Capsaicin; Histamine; Humans; In Vitro Techniques; Leukotriene B4; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Poaceae; Pulmonary Artery; Pulmonary Veins; Serotonin | 1984 |
Pharmacological responses by different portions of guinea pig vas deferens circular muscle preparation.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Barium; Barium Compounds; Carbachol; Chlorides; Dose-Response Relationship, Drug; Ephedrine; Epinephrine; Guinea Pigs; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Norepinephrine; Parasympatholytics; Tyramine; Vas Deferens | 1981 |
In vitro study of the inhibitory effects of dopamine on the rat gastric fundus.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dopamine; Dopamine Antagonists; Drug Interactions; Electric Stimulation; Female; Gastric Fundus; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stomach | 1983 |
Contractions in bronchial musculature of rabbit and man in response to various drugs.
Topics: Acetylcholine; Animals; Bronchi; Choline; Epinephrine; Histamine; Humans; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Rabbits | 1983 |
Pharmacological characterization of the postjunctional beta-adrenoceptors in the rat gastric fundus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Female; Gastric Fundus; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neuromuscular Junction; Rats; Receptors, Adrenergic, beta | 1984 |
Differentiation of functional adrenoceptors in human and guinea pig airways.
Topics: Anaphylaxis; Animals; Bronchi; Corticosterone; Guinea Pigs; Histamine Release; Humans; Immunization; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Ovalbumin; Phenoxybenzamine; Practolol; Receptors, Adrenergic; Receptors, Neurotransmitter; Trachea | 1984 |
Comparison of muscarinic and beta adrenergic receptors between bovine peripheral lung and tracheal smooth muscles: a striking difference in the receptor concentration.
Topics: Animals; Cattle; Epinephrine; In Vitro Techniques; Lung; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Muscarinic; Trachea | 1982 |
Functional antagonism in canine tracheal smooth muscle: inhibition by methacholine of the mechanical and biochemical responses to isoproterenol.
Topics: Animals; Cyclic AMP; Dogs; Enzyme Activation; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Protein Kinases; Receptors, Muscarinic; Trachea | 1983 |
Role of mediators in allergic and nonallergic asthma in dogs with hyperreactive airways.
Topics: Airway Resistance; Animals; Asthma; Bronchial Provocation Tests; Chromones; Citrates; Citric Acid; Dogs; Guinea Pigs; Histamine; Hypersensitivity; Lung Compliance; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Respiratory Tract Diseases; Tissue Extracts | 1983 |
Respiratory responses to leukotrienes and biogenic amines in normal and hyperreactive rats.
Topics: Animals; Dose-Response Relationship, Drug; Dyspnea; Female; Histamine; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred F344; Rats, Inbred Strains; Respiratory Function Tests; Respiratory Hypersensitivity; Serotonin; SRS-A; Trachea | 1983 |
Pharmacological characterization of effects of nifedipine on isolated guinea-pig and rat tracheal smooth muscle.
Topics: Airway Resistance; Animals; Calcium Channel Blockers; Calcium Chloride; Drug Interactions; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Pyridines; Rats; Rats, Inbred Strains; Serotonin; Trachea | 1983 |
In vitro study of the influence of dopamine on rat and dog gastric fundus.
Topics: Animals; Dogs; Dopamine; Dopamine Antagonists; Electric Stimulation; Gastric Fundus; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Rats | 1984 |
Effects of cytochrome P-450 inhibitors on endothelium-dependent relaxation in rabbit aorta.
Topics: Animals; Aorta; Calcium; Cytochrome P-450 Enzyme Inhibitors; Endothelium; Ionophores; Male; Methacholine Chloride; Methacholine Compounds; Metyrapone; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Proadifen; Rabbits | 1984 |
Synthesis and antiarrhythmic and parasympatholytic properties of substituted phenols. 2. Amides.
Topics: Amides; Animals; Anti-Arrhythmia Agents; Chemical Phenomena; Chemistry; Dogs; Electric Stimulation; Guinea Pigs; Heart Rate; Ileum; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Parasympatholytics; Structure-Activity Relationship | 1984 |
[Effect of dopamine on the rat stomach: an in vitro study].
Topics: Animals; Dopamine; Dopamine Antagonists; Electric Stimulation; Female; Gastric Fundus; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Rats; Receptors, Dopamine | 1984 |
Comparison of in vivo airway responsiveness and in vitro smooth muscle sensitivity to methacholine in man.
Topics: Adult; Aged; Airway Resistance; Bronchi; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Muscle Contraction; Muscle, Smooth; Respiratory Function Tests | 1984 |
Functional evidence for sprouting or decentralized parasympathetic neurons in rat urinary bladder.
Topics: Animals; Atropine; Dihydroergotamine; Electric Stimulation; Ganglia, Parasympathetic; Ganglia, Sympathetic; Guanethidine; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Denervation; Neurons; Parasympathetic Nervous System; Parasympathomimetics; Pelvis; Rats; Rats, Inbred Strains; Urinary Bladder | 1984 |
Post-natal change in the effect of denervation on the rat vas deferens.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Norepinephrine; Parasympathomimetics; Quaternary Ammonium Compounds; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Vas Deferens | 1984 |
Development of supersensitivity to methacholine in the rat detrusor following either parasympathetic denervation or decentralization.
Topics: Animals; Denervation; Dose-Response Relationship, Drug; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Organ Size; Potassium; Rats; Urinary Bladder | 1984 |
The relationship between bronchial hyperresponsiveness to methacholine and airway smooth muscle structure and reactivity.
Topics: Adult; Aged; Asthma; Bronchi; Carbachol; Female; Forced Expiratory Volume; Histamine; Humans; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Muscle Contraction; Muscle, Smooth; Respiration; Smoking; Vital Capacity | 1984 |
Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Bacterial Agents; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Calcimycin; Endothelium; Indomethacin; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Prostaglandin Antagonists; Quinacrine; Rabbits | 1983 |
Muscarinic cholinergic agonists at picomolar to nanomolar concentrations produce contractions of isolated rat aortae.
Topics: Animals; Aorta, Thoracic; Atropine; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic | 1982 |
Relaxant effect of trapidil on isolated dog bronchus.
Topics: Animals; Atropine; Bronchi; Bronchodilator Agents; Dogs; Female; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Pyrimidines; Tranylcypromine; Trapidil | 1982 |
Influence of castration upon trophism and reactivity of rat seminal vesicles.
Topics: Acetylcholine; Animals; Atrophy; Castration; Dose-Response Relationship, Drug; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Organ Size; Rats; Seminal Vesicles | 1982 |
Measurement of airway response by isometric and nonisometric techniques in situ.
Topics: Airway Resistance; Animals; Dogs; Dose-Response Relationship, Drug; In Vitro Techniques; Lung Compliance; Methacholine Chloride; Methacholine Compounds; Methods; Muscle Contraction; Muscle, Smooth; Norepinephrine; Trachea | 1982 |
Pharmacological responses of human and porcine lung parenchyma, bronchus and pulmonary artery.
Topics: Animals; Bronchi; Carbachol; Dimethylphenylpiperazinium Iodide; Humans; In Vitro Techniques; Lung; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Pulmonary Artery; Species Specificity; Swine | 1982 |
Pancuronium masks the prejunctional muscarinic autoreceptor in guinea pig tracheal smooth muscle.
Topics: Animals; Autoreceptors; Female; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Neuromuscular Nondepolarizing Agents; Pancuronium; Receptors, Muscarinic; Trachea | 1995 |
Role of nitric oxide in the peristalsis in the isolated guinea-pig ileum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Methacholine Chloride; Models, Biological; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peristalsis | 1994 |
Tachykinin receptors involved in the contractile effect of the natural tachykinins in the rat gastric fundus.
Topics: Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Gastric Fundus; Indoles; Isoindoles; Male; Methacholine Chloride; Muscle Contraction; Neurokinin A; Neurokinin B; Peptide Fragments; Peptides, Cyclic; Rats; Receptors, Tachykinin; Substance P; Tachykinins | 1994 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1995 |
Calcium-and G-protein-related spasmolytic effects of nonsteroidal anti-inflammatory drugs on rat uterus contractions in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Calcium Chloride; Diclofenac; Dinoprost; Female; GTP-Binding Proteins; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pertussis Toxin; Rats; Rats, Wistar; Uterine Contraction; Virulence Factors, Bordetella | 1995 |
No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea.
Topics: Animals; Bronchoconstrictor Agents; Cattle; Dose-Response Relationship, Drug; Gallamine Triethiodide; Histamine; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea | 1995 |
Airways of a hyperresponsive rat strain show decreased relaxant responses to sodium nitroprusside.
Topics: Animals; Carbachol; Cyclic GMP; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitrites; Nitroprusside; Nucleotides, Cyclic; Rats; Rats, Inbred ACI; Rats, Inbred F344; Rats, Inbred Lew; Respiratory Hypersensitivity; Trachea | 1995 |
Suppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP-specific phosphodiesterase: comparison with rolipram.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta; Base Sequence; Benzamides; Blood Proteins; Cattle; Cyclic AMP; DNA Primers; Eosinophil Granule Proteins; Eosinophils; Glutathione; Guinea Pigs; Male; Methacholine Chloride; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Protein Binding; Pyridines; Pyrrolidinones; Ribonucleases; Rolipram; Superoxides; Swine; Vanadates | 1995 |
Effect of an inhibitor of nitric oxide synthase on neural relaxation of human bronchi.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bronchi; Chymotrypsin; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Humans; In Vitro Techniques; Isoproterenol; Lung Neoplasms; Male; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Trachea; Vasoactive Intestinal Peptide | 1993 |
Regulation of airway muscarinic cholinergic receptor subtypes by chronic anticholinergic treatment.
Topics: Animals; Atropine; Bronchi; Drug Administration Schedule; Female; Kinetics; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, Adrenergic, beta; Receptors, Muscarinic; Time Factors; Trachea; Up-Regulation | 1995 |
Effect of transpulmonary pressure on airway closure in immature and mature rabbits.
Topics: Acetylcholine; Air Pressure; Animals; Histamine; In Vitro Techniques; Lung; Methacholine Chloride; Muscle Contraction; Muscle Development; Muscle, Smooth; Positive-Pressure Respiration; Pulmonary Alveoli; Rabbits; Respiratory Function Tests; Respiratory Physiological Phenomena; Respiratory System | 1995 |
Effects of lung volume and surface forces on maximal airway smooth muscle shortening.
Topics: Airway Resistance; Animals; Lung; Lung Volume Measurements; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Paraffin Embedding; Perfusion; Rats; Rats, Wistar | 1994 |
Screening of cattle urine samples for the presence of beta-agonists with a functional test: some preliminary results.
Topics: Adrenergic beta-Agonists; Animals; Cattle; Chromatography, Ion Exchange; Clenbuterol; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Sensitivity and Specificity; Trachea | 1994 |
The interaction of alpha-human atrial natriuretic peptide (ANP) with salbutamol, sodium nitroprusside and isosorbide dinitrate in human bronchial smooth muscle.
Topics: Albuterol; Atrial Natriuretic Factor; Bronchi; Bronchodilator Agents; Drug Synergism; Humans; In Vitro Techniques; Isosorbide Dinitrate; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nitroprusside | 1994 |
Different muscarinic receptor subtypes mediating the phasic activity and basal tone of pig isolated intravesical ureter.
Topics: Animals; Dose-Response Relationship, Drug; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Receptors, Muscarinic; Swine; Ureter | 1993 |
Involvement of muscarinic M2 and M3, but not of M1 and M4 receptors in vagally stimulated contractions of rabbit bronchus/trachea.
Topics: Animals; Electric Stimulation; Ganglia, Parasympathetic; Guinea Pigs; Ileum; Linear Models; Male; Methacholine Chloride; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, Muscarinic; Trachea; Vagus Nerve; Vas Deferens | 1994 |
The effect of Ca2+ on the translocation of protein kinase C in bovine tracheal smooth muscle.
Topics: Animals; Calcium; Cattle; Cytosol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitroprusside; Potassium; Protein Kinase C; Trachea; Verapamil | 1994 |
Effects of activated eosinophils cultured from human umbilical cord blood on guinea pig trachealis.
Topics: Animals; Blood Cells; Cells, Cultured; Eosinophils; Fetal Blood; Guinea Pigs; Humans; Leukotriene C4; Lipoxygenase Inhibitors; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Peroxidase; Trachea | 1993 |
Development of cholinergic innervation and muscarinic receptor subtypes in piglet trachea.
Topics: Administration, Topical; Animals; Animals, Newborn; Electric Stimulation; GTP-Binding Proteins; Methacholine Chloride; Muscle Contraction; Parasympathetic Nervous System; Pirenzepine; Receptors, Muscarinic; Swine; Trachea; Vagus Nerve | 1993 |
Contractile effects of nucleotides in guinea pig isolated, perfused trachea: involvement of respiratory epithelium, prostanoids and Na+ and Cl- channels.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Animals; Chloride Channels; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Kinetics; Male; Membrane Proteins; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nucleotides; Perfusion; Prostaglandins; Receptors, Purinergic; Sodium Channels; Trachea; Uridine Triphosphate | 1993 |
Impaired beta-adrenergic receptor activation of adenylyl cyclase in airway smooth muscle in the basenji-greyhound dog model of airway hyperresponsiveness.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bucladesine; Cholera Toxin; Colforsin; Dinoprostone; Disease Models, Animal; Dogs; Enzyme Activation; Immunoblotting; Isoproterenol; Lung; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Radioimmunoassay; Receptors, Adrenergic, beta; Trachea | 1993 |
Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes.
Topics: Albuterol; Animals; Bronchi; Cattle; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Mice; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phosphodiesterase Inhibitors; Pyridazines; Pyrrolidinones; Rolipram; Trachea | 1993 |
Maximal bronchoconstriction in humans. Relationship to deep inhalation and airway sensitivity.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Data Interpretation, Statistical; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Models, Biological; Muscle Contraction; Muscle, Smooth; Respiration; Respiratory Function Tests | 1996 |
Preparation of bovine tracheal smooth muscle for in vitro pharmacological studies.
Topics: Airway Resistance; Albuterol; Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle; Female; Histamine; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium Chloride; Trachea | 1995 |
Correlation of cyclic AMP accumulation and relaxant actions of salmeterol and salbutamol in bovine tracheal smooth muscle.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Cattle; Cyclic AMP; Histamine Antagonists; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Parasympathomimetics; Salmeterol Xinafoate; Second Messenger Systems; Trachea | 1995 |
Mediators of arachidonic acid-induced relaxation of bovine coronary artery.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Bradykinin; Cattle; Chromatography, High Pressure Liquid; Coronary Vessels; Cyclic GMP; Epoprostenol; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Radioimmunoassay | 1996 |
Agonist synergism in airway smooth muscle contraction.
Topics: Animals; Calcium; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Respiratory System; Serotonin | 1996 |
Modulation of agonist-induced phosphoinositide metabolism, Ca2+ signalling and contraction of airway smooth muscle by cyclic AMP-dependent mechanisms.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Calcium; Cattle; Cells, Cultured; Cholinergic Agents; Colforsin; Cyclic AMP; Histamine; Isoproterenol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Signal Transduction; Trachea | 1996 |
Platelet-activating factor (PAF) stimulates giant migrating contractions during ileal inflammation.
Topics: Animals; Calcium; Dogs; Female; Ileitis; Ileum; Male; Methacholine Chloride; Motilin; Muscle Contraction; Neostigmine; Platelet Activating Factor; Substance P | 1996 |
The effect of isoenzyme-selective PDE inhibitors on methacholine-induced contraction of guinea-pig and rat ileum.
Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Isoproterenol; Male; Methacholine Chloride; Muscle Contraction; Phosphodiesterase Inhibitors; Purinones; Rats; Rats, Sprague-Dawley; Vinca Alkaloids | 1996 |
Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats.
Topics: Animals; Benzopyrans; Blood Glucose; Calcium Channels; Calcium Chloride; Cromakalim; Glyburide; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Methacholine Chloride; Methoxamine; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitroprusside; Norepinephrine; Obesity; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Zucker; Serotonin; Tunica Media; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
G-proteins in guinea pig airway smooth muscle: identification and functional involvement.
Topics: Animals; GTP-Binding Proteins; Guinea Pigs; Immunoblotting; In Vitro Techniques; Kinetics; Male; Membranes; Methacholine Chloride; Microsomes; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Trachea | 1996 |
Influence of parainfluenza-1 respiratory tract viral infection on endothelin receptor-effector systems in mouse and rat tracheal smooth muscle.
Topics: Animals; Endothelin Receptor Antagonists; Endothelin-1; In Vitro Techniques; Male; Methacholine Chloride; Mice; Mice, Inbred CBA; Muscle Contraction; Muscle, Smooth; Parainfluenza Virus 1, Human; Peptides, Cyclic; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Respiratory Tract Infections; Respirovirus Infections; Time Factors; Trachea; Vasoconstrictor Agents; Viper Venoms | 1996 |
Endogenous nitric oxide contributes to strain-related differences in airway responsiveness in rats.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Epithelium; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Inbred F344; Rats, Inbred Lew; Respiratory Mechanics; Species Specificity; Trachea | 1996 |
Methacholine-induced bronchoconstriction and airway smooth muscle in the guinea pig.
Topics: Airway Resistance; Animals; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Freezing; Guinea Pigs; In Vitro Techniques; Lung; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth | 1996 |
Deficiency of nitric oxide in allergen-induced airway hyperreactivity to contractile agonists after the early asthmatic reaction: an ex vivo study.
Topics: Allergens; Animals; Asthma; Guinea Pigs; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Trachea | 1996 |
Relaxant effect of levcromakalim in isolated human small subcutaneous arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Adolescent; Adult; Arteries; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; Female; Glyburide; Humans; In Vitro Techniques; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Skin; Thromboxane A2; Vasoconstrictor Agents | 1995 |
Effect of aspiration of milk on mechanisms of neural control in the airways of developing rabbits.
Topics: Animals; Animals, Newborn; Autonomic Nervous System; Electric Stimulation; Methacholine Chloride; Milk; Muscle Contraction; Muscle, Smooth; Neurokinin A; Pneumonia, Aspiration; Rabbits; Trachea | 1997 |
Morphology and function of preserved microvascular arterial grafts: an experimental study in rats.
Topics: Adenosine; Adrenergic alpha-Agonists; Allopurinol; Animals; Aorta; Arteries; Carotid Artery, Common; Endothelium, Vascular; Female; Glutathione; In Vitro Techniques; Insulin; Male; Methacholine Chloride; Microsurgery; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; Organ Preservation; Organ Preservation Solutions; Phenylephrine; Potassium Chloride; Raffinose; Rats; Rats, Inbred BN; Rats, Wistar; Time Factors; Transplantation, Autologous; Transplantation, Homologous; Transplantation, Isogeneic; Vascular Patency | 1997 |
Characterization of muscarinic receptors in equine tracheal smooth muscle in vitro.
Topics: Animals; Drug Interactions; Horses; In Vitro Techniques; Male; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pilocarpine; Receptors, Muscarinic; Trachea | 1997 |
Heterogeneity of responsiveness of individual airways in cultured lung explants.
Topics: Bronchi; Bronchoconstrictor Agents; Humans; Individuality; Lung; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Organ Culture Techniques; Trachea | 1997 |
Lysophosphatidic acid enhances contractility of isolated airway smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Cats; Dose-Response Relationship, Drug; Endothelium; In Vitro Techniques; Isometric Contraction; Isoproterenol; Lysophospholipids; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Parasympathomimetics; Potassium Chloride; Rabbits | 1997 |
Contribution of type I NOS to expired gas NO and bronchial responsiveness in mice.
Topics: Animals; Brain; Bronchi; Female; Humans; Isoenzymes; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred Strains; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Respiration; Respiration, Artificial; Sequence Deletion | 1997 |
Mechanism of capsaicin-induced relaxation in equine tracheal smooth muscle.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Charybdotoxin; Chymotrypsin; Epithelial Cells; Horses; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurons, Afferent; Neuropeptides; Nitric Oxide; Nitroarginine; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Substance P; Trachea; Vasoactive Intestinal Peptide | 1997 |
Dynamic properties of lung parenchyma: mechanical contributions of fiber network and interstitial cells.
Topics: Animals; Biomechanical Phenomena; Connective Tissue; Connective Tissue Cells; Elasticity; Guinea Pigs; In Vitro Techniques; Lung; Male; Methacholine Chloride; Models, Biological; Muscle Contraction; Muscle Fibers, Skeletal; Parasympathomimetics; Viscosity | 1997 |
CD23 deficient mice develop allergic airway hyperresponsiveness following sensitization with ovalbumin.
Topics: Allergens; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Enzyme-Linked Immunosorbent Assay; Eosinophils; Hypersensitivity, Immediate; Immunoglobulin E; Immunoglobulin G; In Vitro Techniques; Lung; Lymphocyte Activation; Methacholine Chloride; Mice; Muscle Contraction; Ovalbumin; Receptors, IgE; Trachea | 1997 |
Methacholine-induced contraction of rabbit pulmonary artery: role of platelet-endothelial transcellular thromboxane synthesis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Endothelium, Vascular; In Vitro Techniques; Male; Methacholine Chloride; Models, Cardiovascular; Muscle Contraction; Muscle, Smooth, Vascular; Pulmonary Artery; Rabbits; Thromboxane A2; Vasoconstriction | 1998 |
Human respiratory syncytial virus produces prolonged alterations of neural control in airways of developing ferrets.
Topics: Animals; Ferrets; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Trachea | 1998 |
Capsaicin treatment induces muscarinic hyperreactivity in guinea pig trachea: a warning.
Topics: Animals; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Receptors, Muscarinic; Receptors, Tachykinin; Trachea | 1998 |
Effect of gammalinolenic acid, dihomogammalinolenic acid, ascorbyl-6-gammalinolenic acid, and ascorbyl-6-dihomo gammalinolenic acid on histamine- and methacholine-induced contraction of the isolated guinea pig tracheal chain.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Ascorbic Acid; Bronchoconstrictor Agents; Fatty Acids, Unsaturated; gamma-Linolenic Acid; Guinea Pigs; Histamine; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Trachea | 1998 |
Novel adaptation of a method to assess responsiveness of bronchial segments in vitro.
Topics: Acetylcholine; Animals; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Dogs; Dose-Response Relationship, Drug; Epithelium; In Vitro Techniques; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Reproducibility of Results | 1998 |
The effect of L-arginine on guinea-pig and rabbit airway smooth muscle function in vitro.
Topics: Animals; Arginine; Bronchi; Bronchoconstrictor Agents; Enzyme Inhibitors; Epithelium; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Lysine; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Rabbits; Trachea | 1998 |
Effect of time-varying load on degree of bronchoconstriction in the dog.
Topics: Animals; Bronchoconstriction; Dogs; Lung; Lung Volume Measurements; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Reproducibility of Results; Time Factors | 1998 |
Characterization of neural control and contractile function in airway smooth muscle of the ferret.
Topics: Acetylcholine; Adrenergic Agonists; Animals; Bronchoconstriction; Bronchoconstrictor Agents; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Electric Stimulation; Ferrets; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Neostigmine; Neurons; Trachea | 1998 |
Inhibition of beta-adrenergic desensitization by KCa channels in human trachealis.
Topics: Adjuvants, Immunologic; Adrenergic beta-Agonists; Aged; Bronchoconstrictor Agents; Cholera Toxin; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Isoproterenol; Large-Conductance Calcium-Activated Potassium Channels; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle, Smooth; Peptides; Potassium Channels; Potassium Channels, Calcium-Activated; Receptors, Adrenergic, beta; Scorpion Venoms; Trachea | 1999 |
Effects of load and tone on the mechanics of isolated human bronchial smooth muscle.
Topics: Albuterol; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Data Interpretation, Statistical; Electric Stimulation; Humans; In Vitro Techniques; Isometric Contraction; Isotonic Contraction; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth | 1999 |
Osmotic regulation of airway reactivity by epithelium.
Topics: Animals; Biological Transport; Bronchoconstrictor Agents; Chloride Channels; Electric Stimulation; Enzyme Inhibitors; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Acid; Nitric Oxide; Prostaglandin Antagonists; Respiratory Physiological Phenomena; Sodium Channel Blockers; Trachea; Water-Electrolyte Balance | 1999 |
Effect of SR-140333, a neurokinin-1 receptor antagonist, on airway reactivity to methacholine in sedated rats.
Topics: Albuterol; Animals; Atropine; Female; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Respiration; Trachea | 1997 |
Antimuscarinic, calcium channel blocker and tachykinin NK2 receptor antagonist actions of otilonium bromide in the circular muscle of guinea-pig colon.
Topics: Animals; Calcium Channel Blockers; Colon; Gastrointestinal Motility; Guinea Pigs; Male; Membrane Potentials; Methacholine Chloride; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Quaternary Ammonium Compounds; Radioligand Assay; Receptors, Tachykinin | 1999 |
Interaction between blood flow and motility in normal and inflamed ileum.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Dogs; Female; Gastrointestinal Motility; Ileitis; Ileum; Infusions, Intra-Arterial; Intestine, Small; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Phentolamine; Regional Blood Flow; Splanchnic Circulation; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Chronic exposure to hypoxia attenuates contractile responses in rat airways in vitro: a possible role for nitric oxide.
Topics: Albuterol; Animals; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Epithelium; Hypoxia; In Vitro Techniques; Indomethacin; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Potassium Chloride; Rats; Rats, Wistar; Trachea | 1999 |
Ovalbumin aeroallergen exposure-response in Brown Norway rats.
Topics: Aerosols; Allergens; Animals; Dose-Response Relationship, Immunologic; Immunoglobulins; In Vitro Techniques; Lung; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Ovalbumin; Perfusion; Rats; Rats, Inbred BN; Trachea | 2000 |
Lipopolysaccharide-induced lung injury in mice. II. Evaluation of functional damage in isolated parenchyma strips.
Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Bradykinin; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Histamine; Lipopolysaccharides; Lung Diseases; Methacholine Chloride; Mice; Muscle Contraction; Pentoxifylline; Serotonin; Substance P | 2000 |
Enteric locus of action of prokinetics: ABT-229, motilin, and erythromycin.
Topics: Animals; Atropine; Cell Size; Cells, Cultured; Dogs; Duodenum; Electric Stimulation; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Motility; Hexamethonium; In Vitro Techniques; Infusions, Intra-Arterial; Intestinal Mucosa; Jejunum; Male; Methacholine Chloride; Motilin; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Rabbits; Stomach; Tetrodotoxin | 2000 |
Involvement of K(+) channel in procainamide-induced relaxation of bovine tracheal smooth muscle.
Topics: Albuterol; Animals; Anti-Arrhythmia Agents; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle; In Vitro Techniques; Methacholine Chloride; Mexiletine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium; Potassium Channels; Procainamide; Propafenone; Quinidine; Trachea | 2000 |
Airway closure with high PEEP in vivo.
Topics: Animals; Bronchoconstrictor Agents; Dogs; Dose-Response Relationship, Drug; Lung; Lung Volume Measurements; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Positive-Pressure Respiration; Respiratory Physiological Phenomena | 2000 |
NO is involved in MCh-induced accentuated antagonism via type II PDE in the canine blood-perfused SA node.
Topics: Acetylcholine; Animals; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exonucleases; Female; Heart Rate; In Vitro Techniques; Male; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; Papillary Muscles; Receptors, Adrenergic, beta; Sinoatrial Node | 2000 |
Role of K+ channels in N-acetylprocainamide-induced relaxation of bovine tracheal smooth muscle.
Topics: Acecainide; Animals; Barium; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Procainamide; Trachea | 2001 |
Conditioned medium from hypoxic cytotrophoblasts alters arterial function.
Topics: Adrenergic alpha-Agonists; Animals; Cell Hypoxia; Culture Media, Conditioned; Dose-Response Relationship, Drug; Female; Male; Mesenteric Arteries; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Trophoblasts; Vascular Resistance; Vasoconstrictor Agents | 2001 |
Regulation of acetylcholinesterase in cultured muscle by chemical agents and electrical stimulation.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Cells, Cultured; Chick Embryo; Choline; Creatine Kinase; Electric Stimulation; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Skeletal; Nicotinic Antagonists; Tetrodotoxin; Tubocurarine | 1976 |
Effects of fenoterol on beta-adrenoceptor and muscarinic M2 receptor function in bovine tracheal smooth muscle.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cattle; Drug Interactions; Fenoterol; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pertussis Toxin; Receptor, Muscarinic M2; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea; Virulence Factors, Bordetella | 2001 |
Hard metal-induced disease: effects of metal cations in vitro on guinea pig isolated airways.
Topics: Alloys; Animals; Bronchoconstrictor Agents; Cadmium Chloride; Cations; Chlorides; Chromium Compounds; Cobalt; Drug Interactions; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nickel; Solubility; Tantalum; Trachea; Tungsten; Zinc Compounds | 2001 |
Differential effects of anandamide on acetylcholine release in the guinea-pig ileum mediated via vanilloid and non-CB1 cannabinoid receptors.
Topics: Acetylcholine; Animals; Arachidonic Acids; Camphanes; Capsaicin; Cyclohexanols; Dose-Response Relationship, Drug; Electric Stimulation; Endocannabinoids; Guinea Pigs; Ileum; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2001 |
Role of lysophosphatidylcholine in the desensitization of beta-adrenergic receptors by Ca(2+) sensitization in tracheal smooth muscle.
Topics: Adenylate Cyclase Toxin; Adrenergic beta-Agonists; Amides; Animals; Bucladesine; Calcium; Cholera Toxin; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Indoles; Isoproterenol; Lysophosphatidylcholines; Male; Maleimides; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pyridines; Receptors, Adrenergic, beta; rho GTP-Binding Proteins; Spectrometry, Fluorescence; Theophylline; Trachea; Virulence Factors, Bordetella | 2001 |
Effect of fenoterol-induced constitutive beta(2)-adrenoceptor activity on contractile receptor function in airway smooth muscle.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Cattle; Dose-Response Relationship, Drug; Drug Interactions; Fenoterol; Histamine; In Vitro Techniques; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Receptors, Adrenergic, beta-2; Timolol; Trachea | 2001 |
Acetamide-45 inhibits histamine-and methacholine-induced contraction of isolated guinea pig trachea.
Topics: Animals; Anti-Allergic Agents; Bronchoconstrictor Agents; Drug Interactions; Guinea Pigs; Histamine; In Vitro Techniques; Indoleacetic Acids; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Polyunsaturated Alkamides; Pyridines; Trachea | 2002 |
Regulation of capacitative and noncapacitative receptor-operated Ca2+ entry by rho-kinase in tracheal smooth muscle.
Topics: Actins; Amides; Animals; Calcium Channel Blockers; Calcium Signaling; Cytoskeleton; Enzyme Inhibitors; Guinea Pigs; Histamine; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Sarcoplasmic Reticulum; Signal Transduction; Trachea | 2002 |
Intestinal smooth muscle dysfunction after intraperitoneal injection of zymosan in the rat: are oxygen radicals involved?
Topics: Animals; Cyclic AMP; Free Radicals; Glutathione; In Vitro Techniques; Intestine, Small; Isoproterenol; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Oxygen; Peritonitis; Peroxidase; Rats; Rats, Inbred Strains; Zymosan | 1992 |
Contractile agonists activate voltage-dependent calcium channels in airway smooth muscle cells.
Topics: Bradykinin; Calcium Channels; Cells, Cultured; Electrophysiology; Humans; Membrane Potentials; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Probability; Tissue Distribution; Trachea | 1992 |
Influence of vasoactive intestinal polypeptide and NG-nitro-L-arginine methyl ester on cholinergic neurotransmission in the rat gastric fundus.
Topics: Acetylcholine; Animals; Arginine; Electric Stimulation; Female; Gastric Fundus; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Parasympathetic Nervous System; Rats; Rats, Wistar; Synaptic Transmission; Vasoactive Intestinal Peptide | 1992 |
Translocation of protein kinase C in bovine tracheal smooth muscle strips: the effect of methacholine and isoprenaline.
Topics: Analysis of Variance; Animals; Cattle; Cyclic AMP; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Protein Kinase C; Trachea | 1992 |
Characterization of muscarinic receptors that mediate contraction of guinea-pig isolated trachea to choline esters: effect of removing epithelium.
Topics: Acetylcholine; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Dose-Response Relationship, Drug; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Oxotremorine; Receptors, Muscarinic; Trachea | 1992 |
The perfused human bronchiolar tube characteristics of a new model.
Topics: Adult; Aged; Analysis of Variance; Bronchi; Female; Humans; Methacholine Chloride; Middle Aged; Models, Biological; Mucous Membrane; Muscle Contraction; Perfusion; Pulmonary Ventilation; Serous Membrane | 1992 |
Effect of bronchial smooth muscle contraction on lung compliance.
Topics: Airway Resistance; Animals; Bronchi; Lung; Lung Compliance; Male; Methacholine Chloride; Microscopy, Electron, Scanning; Muscle Contraction; Muscle, Smooth; Respiratory Mechanics; Sheep | 1992 |
A minority of muscarinic receptors mediate rabbit tracheal smooth muscle contraction.
Topics: Animals; Atropine; Female; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myocardium; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Radioligand Assay; Receptors, Muscarinic; Trachea | 1992 |
Effects of endothelin-1 on tracheal submucosal gland secretion and epithelial function in the ferret.
Topics: Albumins; Animals; Dose-Response Relationship, Drug; Endothelins; Epithelium; Ferrets; In Vitro Techniques; Membrane Potentials; Methacholine Chloride; Muramidase; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Pressure; Trachea | 1992 |
Relationship between quasi-static pulmonary hysteresis and maximal airway narrowing in humans.
Topics: Adult; Asthma; Bronchoconstriction; Female; Forced Expiratory Volume; Humans; Lung; Male; Methacholine Chloride; Muscle Contraction; Respiratory Mechanics | 1992 |
A muscarinic receptor different from the M1, M2, M3 and M4 subtypes mediates the contraction of the rabbit iris sphincter.
Topics: Animals; Evoked Potentials; Female; Guinea Pigs; Iris; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, Muscarinic | 1992 |
Is protein kinase C involved in histamine H1-receptor desensitization?
Topics: Animals; Cyclic GMP; Drug Tolerance; Guinea Pigs; Histamine; Ionomycin; Jejunum; Kinetics; Lung; Male; Methacholine Chloride; Muscle Contraction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Histamine H1 | 1991 |
The lipid peroxidation product 4-hydroxy-2,3-trans-1 nonenal decreases rat intestinal smooth muscle function in-vitro by alkylation of sulphydryl groups.
Topics: Aldehydes; Alkylation; Animals; Drug Interactions; Ethylmaleimide; Intestine, Small; Isoproterenol; Lipid Peroxidation; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sulfhydryl Compounds | 1991 |
Effect of epithelial denudation, inflammatory mediators and mast cell activation on the sensitivity of isolated human airways to methacholine.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Aged, 80 and over; Antibodies, Anti-Idiotypic; Dinoprost; Epithelium; Histamine; Humans; Hypersensitivity; Immunoglobulin E; In Vitro Techniques; Inflammation; Kinetics; Lung; Male; Mast Cells; Methacholine Chloride; Middle Aged; Muscle Contraction; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; SRS-A | 1991 |
Endothelium-dependent contraction and relaxation of the human and canine internal mammary artery: studies on bypass graft vasospasm.
Topics: Acetylcholine; Animals; Arginine; Dogs; Endothelins; Female; Humans; Hypoxia; In Vitro Techniques; Male; Mammary Arteries; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Norepinephrine; omega-N-Methylarginine | 1991 |
Regulation of sympathetic and parasympathetic receptor responses in the rat trachea by epithelium: influence of mechanical and chemical removal of epithelium.
Topics: Animals; Benzene Derivatives; Epithelium; Isoproterenol; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea | 1990 |
A new class of calcium antagonists. 2. Synthesis and biological activity of 11-[[4-[4-(4-fluorophenyl)-1-piperazinyl]butyryl]amino]-6,11- dihydrodibenzo[b,e]-thiepin maleate and related compounds.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Chemistry, Physical; Dibenzothiepins; Heart Rate; Hypertension; Male; Methacholine Chloride; Models, Molecular; Molecular Conformation; Molecular Structure; Muscle Contraction; Muscle, Smooth, Vascular; Piperazines; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasoconstriction | 1991 |
Reserpine-induced post-receptor reduction in muscarinic-mediated airway smooth muscle contraction.
Topics: Animals; Binding, Competitive; Bronchi; Humans; Lung; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Organ Specificity; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Reserpine; Trachea | 1991 |
Maturation of respiratory reflex responses in the piglet.
Topics: Animals; Capsaicin; Chemoreceptor Cells; Gallamine Triethiodide; Hypercapnia; Lung Volume Measurements; Methacholine Chloride; Muscle Contraction; Muscle Development; Muscle, Smooth; Phrenic Nerve; Reflex; Respiratory Mechanics; Respiratory Muscles; Swine; Trachea | 1991 |
The increased responsiveness to inhaled methacholine in asthma: combination of causative factors.
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response Relationship, Drug; Humans; Methacholine Chloride; Muscle Contraction; Muscle, Smooth | 1991 |
Maximal methacholine-induced constriction in rabbit lung: interactions between airways and tissue?
Topics: Airway Resistance; Animals; Lung; Lung Compliance; Male; Methacholine Chloride; Muscle Contraction; Rabbits; Respiratory Mechanics; Respiratory Muscles | 1991 |
Effects of mazindol on the contractions in the rat vas deferens.
Topics: Animals; Dopamine; Electric Stimulation; In Vitro Techniques; Male; Mazindol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Vas Deferens | 1990 |
Dissociation between myosin phosphorylation and shortening velocity in canine trachea.
Topics: Animals; Calcium; Dogs; Egtazic Acid; Female; In Vitro Techniques; Kinetics; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Myosin Subfragments; Myosins; Phosphorylases; Phosphorylation; Serotonin; Trachea | 1990 |
Effects of changes in osmolarity on isolated human airways.
Topics: Adult; Aged; Aged, 80 and over; Bronchi; Calcium; Constriction, Pathologic; Female; Humans; Hypertonic Solutions; Hypotonic Solutions; Isoproterenol; Male; Mannitol; Methacholine Chloride; Methacholine Compounds; Middle Aged; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Saline Solution, Hypertonic; Urea | 1990 |
[The effect of leukotriene C4/D4 receptor antagonist (ONO-1078) and thromboxane A2 synthetase inhibitor (OKY-046) on airway hyperresponsiveness induced by ozone exposure in guinea pigs].
Topics: Acrylates; Administration, Inhalation; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Chromones; Guinea Pigs; Methacholine Chloride; Methacholine Compounds; Methacrylates; Muscle Contraction; Ozone; Receptors, Immunologic; Receptors, Leukotriene; Thromboxane A2 | 1990 |
Effect of sodium-transport inhibitors on airway smooth muscle contractility in vitro.
Topics: Amiloride; Animals; Bronchi; Carbachol; Cattle; Dose-Response Relationship, Drug; Histamine; Humans; In Vitro Techniques; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nifedipine; Ouabain; Phentolamine; Sodium-Potassium-Exchanging ATPase; Trachea | 1990 |
Role of phosphoinositide metabolism in human bronchial smooth muscle contraction and in functional antagonism by beta-adrenoceptor agonists.
Topics: Aged; Bronchi; Histamine; Humans; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Middle Aged; Muscle Contraction; Phosphatidylinositols | 1990 |
Effects of inflammatory mediators on the responsiveness of isolated human airways to methacholine.
Topics: Aged; Bronchi; Dinoprost; Dose-Response Relationship, Drug; Female; Histamine; Humans; In Vitro Techniques; Inflammation; Male; Methacholine Chloride; Middle Aged; Muscle Contraction; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; SRS-A | 1990 |
Inhibitory action of propranolol on the contractions induced by nerve stimulations or calcium in the smooth muscle of rat vas deferens.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Gallopamil; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Norepinephrine; Potassium; Propranolol; Rats; Rats, Inbred Strains; Vas Deferens | 1986 |
REV 5901: an orally effective peptidoleukotriene antagonist, detailed biochemical/pharmacological profile.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Chromones; Coronary Circulation; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Hydroxyquinolines; Kinetics; Lung; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Myocardial Contraction; Quinolines; Regional Blood Flow; SRS-A | 1987 |
Development of a large fibromuscular intimal thickening does not impair endothelium-dependent relaxation in the rabbit carotid artery.
Topics: Animals; Calcimycin; Carotid Arteries; Endothelium; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Rabbits; Serotonin; Substance P; Vasodilator Agents | 1987 |
Peripheral type benzodiazepine receptor and airway smooth muscle relaxation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzodiazepinones; Calcium; Convulsants; Guinea Pigs; In Vitro Techniques; Ion Channels; Lung; Male; Methacholine Chloride; Methacholine Compounds; Midazolam; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium Chloride; Receptors, GABA-A; Trachea | 1988 |
Evidence for a direct relationship between phosphoinositide metabolism and airway smooth muscle contraction induced by muscarinic agonists.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Cattle; Inositol Phosphates; Methacholine Chloride; Methacholine Compounds; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Phosphatidylinositols; Receptors, Muscarinic; Trachea | 1988 |
Okadaic acid, a phosphatase inhibitor, produces a Ca2+ and calmodulin-independent contraction of smooth muscle.
Topics: Animals; Calcium; Calmodulin; Ethers, Cyclic; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Myosins; Okadaic Acid; Osmolar Concentration; Phosphoric Monoester Hydrolases; Phosphorylation; Sheep | 1989 |
Formation of chloramine derivatives of histamine: role of histamine chloramines in bronchoconstriction.
Topics: Animals; Bronchi; Chloramines; Guinea Pigs; Histamine; Humans; Hydrogen-Ion Concentration; Hypochlorous Acid; Kinetics; Lung; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscles; Neutrophils; Peroxidase | 1989 |
Actions of bradykinin and related peptides on rabbit coeliac artery rings.
Topics: Animals; Bradykinin; Celiac Artery; Ibuprofen; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Peptides; Phenylephrine; Rabbits | 1989 |
Translation of contractile force to constriction in major diameter canine airways in vivo.
Topics: Animals; Biomechanical Phenomena; Bronchi; Bronchography; Dogs; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Vasoconstriction | 1989 |
Is the guinea pig trachea a good in vitro model of human large and central airways? Comparison on leukotriene-, methacholine-, histamine- and antigen-induced contractions.
Topics: Adult; Animals; Antigens; Borates; Bronchi; Child; Chromones; Dicarboxylic Acids; Female; Guinea Pigs; Histamine; Humans; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Models, Biological; Muscle Contraction; Receptors, Leukotriene; Receptors, Prostaglandin; Serine; SRS-A; Trachea | 1987 |
Differential inhibitory effects of forskolin, isoproterenol, and dibutyryl cyclic adenosine monophosphate on phosphoinositide hydrolysis in canine tracheal smooth muscle.
Topics: Animals; Bucladesine; Colforsin; Dogs; Histamine; Hydrolysis; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Trachea | 1988 |
Sympathetic denervation does not alter the density or properties of alpha-1 adrenergic receptors in rat vas deferens.
Topics: Animals; In Vitro Techniques; Iodine Radioisotopes; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Norepinephrine; Phenethylamines; Phenoxybenzamine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathectomy; Tetralones; Vas Deferens | 1985 |
Methacholine sensitivity and cAMP protein kinase in tracheal smooth muscle.
Topics: Animals; Cyclic AMP; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Drug Resistance; In Vitro Techniques; Indomethacin; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Propranolol; Protein Kinases; Rest; Trachea | 1986 |
Action of a novel drug (Zy 16039) on mucus secretion in the ferret isolated trachea in vitro.
Topics: Albumins; Animals; Benzopyrans; Dose-Response Relationship, Drug; Ferrets; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Mucus; Muramidase; Muscle Contraction; Phenylephrine; Trachea | 1988 |
Comparison of maximal bronchoconstriction in vivo and airway smooth muscle responses in vitro in nonasthmatic humans.
Topics: Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth | 1988 |
Parenchymal interdependence and airway response to methacholine in excised dog lobes.
Topics: Airway Obstruction; Airway Resistance; Animals; Dogs; In Vitro Techniques; Lung; Lung Volume Measurements; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Pressure; Respiration; Respiratory Muscles | 1988 |
Relationship between in vivo airway reactivity and in vitro responsiveness of tracheal smooth muscle in inbred rats.
Topics: Airway Resistance; Animals; Carbachol; Dose-Response Relationship, Drug; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred F344; Rats, Inbred Lew; Trachea | 1988 |
Agonist-induced contractile responses of human bronchial muscle in vitro: effects of Ca2+ removal, La3+ and PY108068.
Topics: Bronchi; Calcimycin; Calcium; Calcium Channel Blockers; Histamine; Humans; In Vitro Techniques; Lanthanum; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Chloride; SRS-A | 1986 |
Non-pharmacological modulators of airway responsiveness.
Topics: Acetylcholine; Aerosols; Airway Resistance; Animals; Asthma; Bronchial Spasm; Humans; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Nicotiana; Plants, Toxic; Pulmonary Ventilation; Smoke | 1988 |
Comparison of isometric and isotonic responses of human small airway smooth muscle in vitro.
Topics: Bronchi; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth | 1987 |
A disbalance between beta-adrenergic and muscarinic responses caused by hydrogen peroxide in rat airways in vitro.
Topics: Animals; Hydrogen Peroxide; In Vitro Techniques; Isoproterenol; Lung; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Trachea | 1987 |
The effect of lead on cholinergic contractile function in the rat forestomach.
Topics: Administration, Oral; Animals; Drug Interactions; Electric Stimulation; Gastric Emptying; Lead; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Physostigmine; Rats; Rats, Inbred Strains; Stomach | 1987 |
Neural control of contraction in isolated submucosal gland from feline trachea.
Topics: Adrenergic Fibers; Animals; Atropine; Cats; Cholinergic Fibers; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Exocrine Glands; Hexamethonium Compounds; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Neostigmine; Phentolamine; Propranolol; Serotonin; Tetrodotoxin; Trachea | 1987 |
In vitro responses of airways from an asthmatic patient.
Topics: Adult; Asthma; Bronchi; Electric Stimulation; Histamine; Humans; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Parasympatholytics; Solitary Pulmonary Nodule; SRS-A | 1987 |
Distribution of airway contractile responses in major resistance airways of the dog.
Topics: Airway Resistance; Animals; Bronchi; Dogs; Female; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Potassium Chloride | 1987 |
Interactions of a water extract of cotton bract with dog isolated airway smooth muscle.
Topics: Animals; Dinoprost; Dogs; Dose-Response Relationship, Drug; Gossypium; Histamine; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Methysergide; Muscle Contraction; Muscle, Smooth; Prostaglandins F; Trachea | 1986 |
Comparison of drug responses in vivo and in vitro in airways of dogs with and without airway hyperresponsiveness.
Topics: Aerosols; Airway Resistance; Animals; Asthma; Bronchial Provocation Tests; Disease Models, Animal; Dogs; Histamine; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth | 1986 |
Transient supersensitivity in the hypertrophied rat urinary bladder.
Topics: Animals; Choline O-Acetyltransferase; Electric Stimulation; Hypertrophy; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Organ Size; Paraffin; Rats; Rats, Inbred Strains; Urinary Bladder | 1986 |
Disuse as cause of supersensitivity in the rat urinary bladder.
Topics: Animals; Choline O-Acetyltransferase; Hypertrophy; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Organ Size; Rats; Rats, Inbred Strains; Ureter; Urinary Bladder | 1986 |
Contractility of isolated single submucosal gland from trachea.
Topics: Animals; Atropine; Cats; Dogs; Exocrine Glands; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Microscopy, Electron; Mucus; Muscle Contraction; Trachea | 1986 |
The dependence of airway smooth muscle on extracellular Ca2+ for contraction is influenced by the presence of cartilage.
Topics: Animals; Calcium; Cartilage; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Potassium; Rabbits; Trachea | 1986 |
Effects of a cotton bract extract on guinea pig isolated airway smooth muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Atropine; Dialysis; Dose-Response Relationship, Drug; Electric Stimulation; Gossypium; Guinea Pigs; Histamine; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Methysergide; Muscle Contraction; Muscle, Smooth; Plant Extracts; Trachea | 1986 |
Regional differences in relaxation of electric field-stimulated canine airway smooth muscle by verapamil, isoproterenol and prostaglandin E2.
Topics: Animals; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Prostaglandins E; Respiratory System; Tissue Distribution; Verapamil | 1986 |
Epithelium modulates the reactivity of ovalbumin-sensitized guinea-pig airway smooth muscle.
Topics: Animals; Epithelium; Guinea Pigs; Histamine; Immunization; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Ovalbumin; Potassium Chloride; Respiratory Hypersensitivity; Trachea | 1986 |
Unilateral denervation of the rat urinary bladder and reinnervation: a predominance for ipsilateral changes.
Topics: Animals; Atropine; Choline O-Acetyltransferase; Electric Stimulation; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Denervation; Nerve Regeneration; Organ Size; Rats; Rats, Inbred Strains; Urinary Bladder | 1986 |
Dissociation of contraction and muscarinic receptor binding to isolated smooth muscle cells.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; Dogs; Kinetics; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Oxotremorine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Stomach; Temperature | 1986 |
Rociverine citrate: a new spasmolytic agent, potentially useful in the treatment of urinary bladder hyperreflexia.
Topics: Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cyclohexanecarboxylic Acids; Flavoxate; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Potassium; Rats; Reserpine; Urinary Bladder | 1986 |
Isovolumetric and isobaric rabbit tracheal contraction in vitro.
Topics: Animals; Electric Stimulation; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Plethysmography; Pressure; Rabbits; Trachea | 1987 |
Suppression by muscarinic M2 stimulation of the contractile mechanism via histamine H1 receptors in the longitudinal muscle of guinea pig ileum.
Topics: Animals; Atropine; Calcium; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Ileum; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Phentolamine; Pirenzepine; Propranolol; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Temperature; Tetrodotoxin | 1987 |
Biochemical and functional evidence for nerve sprouting in the decentralized, hypertrophied rat urinary bladder.
Topics: Animals; Atropine; Choline O-Acetyltransferase; Cholinergic Fibers; Denervation; Electric Stimulation; Ganglia, Parasympathetic; Hypertrophy; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Organ Size; Rats; Rats, Inbred Strains; Urinary Bladder | 1987 |
Distribution of airway contractile responses within the major diameter bronchi during exogenous bronchoconstriction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Bronchi; Bronchography; Dinoprost; Dogs; Female; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prostaglandin Endoperoxides, Synthetic; Prostaglandins F | 1987 |
Airway reactivity in chronic obstructive pulmonary disease. Failure of in vivo methacholine responsiveness to correlate with cholinergic, adrenergic, or nonadrenergic responses in vitro.
Topics: Aged; Albuterol; Bronchi; Bronchial Provocation Tests; Colforsin; Diterpenes; Female; Forced Expiratory Volume; Humans; In Vitro Techniques; Lung Diseases, Obstructive; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Pneumonectomy | 1985 |
The relative potencies of some agonists at M2 muscarinic receptors in guinea-pig ileum, atria and bronchi.
Topics: Acetylcholine; Animals; Arecoline; Atrial Function; Bronchi; Carbachol; Choline; Guinea Pigs; Heart Rate; Ileum; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Myocardial Contraction; Neostigmine; Receptors, Muscarinic | 1985 |
Motor-stimulating properties of cisapride on isolated gastrointestinal preparations of the guinea pig.
Topics: Acetylcholine; Animals; Atropine; Cisapride; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gastrointestinal Motility; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Intestinal Mucosa; Male; Methacholine Chloride; Methacholine Compounds; Metoclopramide; Muscle Contraction; Nicotine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Tetrodotoxin | 1985 |
Age-related changes in the reactivity of the rat jejunum to cholinoceptor agonists.
Topics: Acetylcholine; Acetylcholinesterase; Aging; Animals; Atropine; Barium; Cholinesterases; In Vitro Techniques; Jejunum; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Potassium Chloride; Rats; Rats, Inbred Strains | 1985 |
Increased in vitro airway responsiveness in sheep following repeated exposure to antigen in vivo.
Topics: Animals; Antigens; Ascaris; Bronchial Spasm; Dinoprost; Histamine; Lung; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Prostaglandins F; Respiratory System; Sheep; Thromboxane A2; Trachea | 1985 |
Organ culture of young rat vas deferens as an in vitro model for the study of denervation supersensitivity.
Topics: Animals; Denervation; Hydroxydopamines; Male; Methacholine Chloride; Methacholine Compounds; Models, Biological; Muscle Contraction; Muscle, Smooth; Norepinephrine; Organ Culture Techniques; Oxidopamine; Rats; Rats, Inbred Strains; Sympathectomy, Chemical; Vas Deferens | 1985 |