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methacholine chloride and Lung Diseases, Obstructive

methacholine chloride has been researched along with Lung Diseases, Obstructive in 74 studies

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199018 (24.32)18.7374
1990's41 (55.41)18.2507
2000's14 (18.92)29.6817
2010's1 (1.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chu, YH; Kao, CH; Liu, SC; Wang, HW; Wu, CC1
Bentur, L; Elhasid, R; Hakim, F; Lapidot, M; Lidroneta-Katz, C; Livnat, G; Porat, I; Vilozni, D1
Bakke, P; Carlsen, KH; Eide, GE; Halvorsen, T; Røksund, OD; Skadberg, BT1
De Castro, FB; De Lucena Ðngulo, I; Martinez, JAB; Terra-Filho, J; Vendramini, EC; Vianna, EO1
Card, JW; Cook, DN; DeGraff, LM; Graham, GJ; Lira, SA; Wang, T; Whitehead, GS1
Carlsen, KC; Carlsen, KH; Devulapalli, CS; Håland, G; Mowinckel, P; Munthe-Kaas, MC; Pettersen, M1
Robbins, JJ1
Lahdensuo, A; Muittari, A; Sovijärvi, A1
Avital, A; Bar-Yishay, E; Godfrey, S; Springer, C1
O'Connor, GT; Sparrow, D; Weiss, ST1
Chareonlap, P; Mogmud, S; Phanuphak, P; Wongtim, S1
Bohadana, AB; Kolopp-Sarda, MN; Massin, N; Toamain, JP; Wild, P1
Avital, A; Picard, E; Springer, C; Uwyyed, K1
Annema, JT; Koëter, GH; O'Connor, GT; Postma, DS; Rijcken, B; Sparrow, D; Weiss, ST1
Baldacci, S; Ballerin, L; Carrozzi, L; Di Pede, F; Grado, L; Modena, P; Paoletti, P; Pedreschi, M; Vellutini, M; Viegi, G1
Frostell, CG; Hedenstierna, G; Hedenström, H; Högman, M1
Altose, MD; Buist, AS; Connett, JE; Kanner, RE; Lee, WW; Tashkin, DP; Wise, RA1
Hassan, WU; Holland, CD; Keaney, NP; Kelly, CA1
Ikeda, A; Izumi, T; Koyama, H; Mio, T; Nishimura, K; Sugiura, N1
Cunningham, FM; Fairbairn, SM; Lees, P; Page, CP1
de Jong, JW; Jansen, MA; Koëter, GH; Oosterhoff, Y; Postma, DS1
Bronnimann, S; Camilli, AE; Lebowitz, MD1
Altose, MD; Connett, JE; Kanner, RE; Lee, WW; Tashkin, DP; Wise, RA1
Dixon, PM; Halliwell, RE; Marley, C; Matthews, AG; McGorum, BC; Morris, JR1
Connolly, MJ; Renwick, DS1
Ikeda, A; Izumi, T; Koyama, H; Mishima, M; Nishimura, K; Sakai, N1
Eide, GE; Gulsvik, A; Omenaas, E1
Brusasco, V; Pellegrino, R; Rodarte, JR1
Owens, GR1
de Jong, JW; Koëter, GH; Postma, DS1
Koëter, GH; Postma, DS; Rutgers, SR; van der Mark, TW2
Anciaux, N; Art, T; Duvivier, DH; Lekeux, P; Van Erck, E; Vandenput, S; Votion, D1
Carlsen, KH; Engh, G; Mørk, M; Schrøder, E1
Honda, K; Kawakami, T; Kobayashi, H; Takahashi, Y; Tanaka, N; Tomita, T1
Morice, AH; Wong, CH1
Hoogsteden, HC; Lambrecht, BN; Prins, JB; Verhoeven, GT1
Hamada, M; Masuyama, K; Tsunematsu, R; Uchida, Y1
Bogaard, JM; de Bruin, H; de Jongste, JC; Hofhuis, W; Hop, WC; Tiddens, HA; Willems, LN1
Quinn, TJ; Schwartz, DA; Taylor, S; Wohlford-Lenane, CL1
Marín, J; Millan, M; Pérez, JA; Peris, R; Prieto, L; Sánchez-Toril, F1
Boere-van der Straat, S; Bogaard, JM; Hoogsteden, HC; Verbraak, AF; Verhoeven, GT1
Fletcher, AM; Francis, HC; Higgins, BG; Pickering, CA; Warburton, CJ; Woodcock, AA; Yates, C1
Kapsali, T; Permutt, S; Scichilone, N; Togias, A1
Koeter, GH; Postma, DS; Rutgers, SR; ten Hacken, NH1
George, CL; Jin, H; Kline, JN; O'Neill, ME; O'Shaughnessy, P; Phipps, JC; Schwartz, DA; Thorne, PS; Wohlford-Lenane, CL1
Ashida, K; Harada, S; Hosaki, Y; Mifune, T; Mitsunobu, F; Okamoto, M; Tanizaki, Y; Tsugeno, H1
Avila, P; Boushey, HA; Fahy, JV; Janson, S; Khashayar, R; Lazarus, SC; Segal, M; Woodruff, PG1
Chan-Yeung, M; Frew, AJ; Kennedy, SM1
Gracely, E; Greenspon, LW1
Coggon, D; Dow, L; Holgate, ST1
Arborelius, M; Hjortsberg, U; Orbaek, P1
Altose, MD; Bleecker, ER; Connett, JE; Kanner, RE; Lee, WW; Tashkin, DP; Wise, R1
Bel, EH; Dijkman, JH; Sterk, PJ; Timmers, MC; Zwinderman, AH1
Anderson, SD; Du Toit, JI; Peat, JK; Salome, CM; Smith, CM; Woolcock, AJ; Zhang, YG1
Hoffarth, HP; Reier, W; Ulmer, WT1
Burrows, B; Chan-Yeung, M; Enarson, DA; Kennedy, SM; Vedal, S1
Tafradzhiĭska, M1
Guillemi, S; James, AL; Pare, PD1
Bruschi, C; Cerveri, I; Grassi, C; Grassi, M; Lebowitz, MD; Maccarini, L; Rampulla, C; Zoia, MC1
Kapfhammer, G; Raber, W1
Ito, T; Kabe, J; Kudo, K; Murakami, S; Sano, Y; Uno-Komase, Y1
Botey, J; Eseverri, JL; López Gil, A; Marín, A1
Hudson, I; Kelly, WJ; Olinsky, A; Pain, MC; Phelan, PD; Raven, J1
Hendrick, D; Kelly, C; Walters, H1
Greenspon, LW; Parrish, B1
Takeda, J1
Britton, J; Tattersfield, AE1
Block, R; Bonta, IL; De Jongste, JC; Frederiksz, AP; Kerrebijn, KF; Mons, H1
Adelroth, EC; Hargreave, FE; O'Byrne, PM; Ramsdale, EH; Sterk, P1
Battista, RN; Becklake, MR; Dales, RE; Ernst, P; Hanley, JA1
Armour, CL; Hogg, JC; Paré, PD; Schellenberg, RR; Taylor, SM1
Cherniack, NS; Deal, EC; Kelsen, SG; Oliven, A2

Reviews

3 review(s) available for methacholine chloride and Lung Diseases, Obstructive

ArticleYear
The significance of airway responsiveness in the onset and evolution of chronic obstructive pulmonary disease.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1997, Volume: 27, Issue:10

    Topics: Antigens, CD19; Bronchial Hyperreactivity; Bronchial Provocation Tests; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Predictive Value of Tests; Smoking; T-Lymphocytes

1997
Airway inflammation in asthma and chronic obstructive pulmonary disease with special emphasis on the antigen-presenting dendritic cell: influence of treatment with fluticasone propionate.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Volume: 29 Suppl 2

    Topics: Androstadienes; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Dendritic Cells; Dose-Response Relationship, Drug; Fluticasone; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Methacholine Chloride

1999
Does measurement of bronchial hyperreactivity help in the clinical diagnosis of asthma?
    European journal of respiratory diseases, 1986, Volume: 68, Issue:4

    Topics: Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds; Reference Values; Smoking

1986

Trials

13 trial(s) available for methacholine chloride and Lung Diseases, Obstructive

ArticleYear
Lung function and airway hyperresponsiveness in adult patients with sickle cell disease.
    The American journal of the medical sciences, 2006, Volume: 332, Issue:2

    Topics: Adolescent; Adult; Age Factors; Anemia, Sickle Cell; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Female; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Respiratory Function Tests; Respiratory Hypersensitivity; Sex Factors

2006
Inhaled powder and aerosol salbutamol in metacholine-induced bronchial obstruction.
    European journal of respiratory diseases. Supplement, 1983, Volume: 128 (Pt 2)

    Topics: Administration, Intranasal; Aerosols; Albuterol; Clinical Trials as Topic; Humans; Lung Diseases, Obstructive; Lung Volume Measurements; Methacholine Chloride; Methacholine Compounds; Powders

1983
Adenosine, methacholine, and exercise challenges in children with asthma or paediatric chronic obstructive pulmonary disease.
    Thorax, 1995, Volume: 50, Issue:5

    Topics: Adenosine Monophosphate; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Child; Diagnosis, Differential; Double-Blind Method; Exercise Test; Female; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Predictive Value of Tests; Sensitivity and Specificity

1995
Comparison of adenosine 5'-monophosphate and methacholine for the differentiation of asthma from chronic airway diseases with the use of the auscultative method in very young children.
    The Journal of pediatrics, 1995, Volume: 127, Issue:3

    Topics: Adenosine Monophosphate; Asthma; Auscultation; Bronchial Provocation Tests; Child, Preschool; Diagnosis, Differential; Double-Blind Method; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Sensitivity and Specificity

1995
Gender difference in airway hyperresponsiveness in smokers with mild COPD. The Lung Health Study.
    American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:4

    Topics: Adult; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; North America; Prevalence; Prospective Studies; Sex Characteristics; Smoking; Statistics as Topic

1994
Methacholine reactivity predicts changes in lung function over time in smokers with early chronic obstructive pulmonary disease. The Lung Health Study Research Group.
    American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:6 Pt 1

    Topics: Bronchoconstrictor Agents; Female; Forced Expiratory Volume; Humans; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Predictive Value of Tests; Respiratory Function Tests; Smoking

1996
Prevalence and treatment of chronic airways obstruction in adults over the age of 45.
    Thorax, 1996, Volume: 51, Issue:2

    Topics: Aged; Aged, 80 and over; Asthma; Bronchitis; Bronchoconstrictor Agents; Bronchodilator Agents; England; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Prevalence; Spirometry; Vital Capacity

1996
Short-term treatment with budesonide does not improve hyperresponsiveness to adenosine 5'-monophosphate in COPD.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:3 Pt 1

    Topics: Adenosine Monophosphate; Administration, Inhalation; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; Budesonide; Cholinergic Antagonists; Female; Forced Expiratory Volume; Glucocorticoids; Histamine; Histamine H1 Antagonists; Humans; Interleukin-8; Ipratropium; Leukocyte Count; Longitudinal Studies; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Neutrophils; Placebos; Smoking; Terfenadine; Time Factors

1998
Cold air inhalation and exercise-induced bronchoconstriction in relationship to metacholine bronchial responsiveness: different patterns in asthmatic children and children with other chronic lung diseases.
    Respiratory medicine, 1998, Volume: 92, Issue:2

    Topics: Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchoconstrictor Agents; Child; Cold Temperature; Diagnosis, Differential; Exercise Tolerance; Female; Forced Expiratory Volume; Humans; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Predictive Value of Tests; Sensitivity and Specificity

1998
Airway inflammation in asthma and chronic obstructive pulmonary disease with special emphasis on the antigen-presenting dendritic cell: influence of treatment with fluticasone propionate.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Volume: 29 Suppl 2

    Topics: Androstadienes; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Dendritic Cells; Dose-Response Relationship, Drug; Fluticasone; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Methacholine Chloride

1999
Protective effect of oral terfenadine and not inhaled ipratropium on adenosine 5'-monophosphate-induced bronchoconstriction in patients with COPD.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Volume: 29, Issue:9

    Topics: Adenosine Monophosphate; Aged; Bronchoconstriction; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine Release; Humans; Ipratropium; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Respiratory Function Tests; Smoking; Terfenadine

1999
The lung health study: airway responsiveness to inhaled methacholine in smokers with mild to moderate airflow limitation. The Lung Health Study Research Group.
    The American review of respiratory disease, 1992, Volume: 145, Issue:2 Pt 1

    Topics: Adult; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Pulmonary Ventilation; Smoking; Vital Capacity

1992
The protective effect of a beta 2 agonist against excessive airway narrowing in response to bronchoconstrictor stimuli in asthma and chronic obstructive lung disease.
    Thorax, 1991, Volume: 46, Issue:1

    Topics: Adult; Aged; Airway Obstruction; Albuterol; Asthma; Bronchoconstriction; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Histamine; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged

1991

Other Studies

59 other study(ies) available for methacholine chloride and Lung Diseases, Obstructive

ArticleYear
Steroids and antihistamines synergize to inhibit rat's airway smooth muscle contractility.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2015, Volume: 272, Issue:6

    Topics: Animals; Cetirizine; Cholinergic Agents; Disease Models, Animal; Drug Synergism; Electric Stimulation; Glucocorticoids; Histamine Antagonists; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Prednisolone; Rats; Rhinitis, Allergic; Trachea; Treatment Outcome

2015
Airway reactivity in children before and after stem cell transplantation.
    Pediatric pulmonology, 2009, Volume: 44, Issue:9

    Topics: Adolescent; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Preschool; Female; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Prospective Studies; Spirometry; Stem Cell Transplantation; Young Adult

2009
Pulmonary outcome in adolescents of extreme preterm birth: a regional cohort study.
    Acta paediatrica (Oslo, Norway : 1992), 2004, Volume: 93, Issue:10

    Topics: Adolescent; Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchopulmonary Dysplasia; Cohort Studies; Female; Forced Expiratory Volume; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Peak Expiratory Flow Rate; Plethysmography; Prevalence; Spirometry

2004
The chemokine receptor D6 has opposing effects on allergic inflammation and airway reactivity.
    American journal of respiratory and critical care medicine, 2007, Feb-01, Volume: 175, Issue:3

    Topics: Allergens; Animals; Bronchial Hyperreactivity; Chemokine Receptor D6; Chemokines, CC; Eosinophils; Inflammation; Leukocytes; Lung; Lung Diseases, Obstructive; Lymph Nodes; Methacholine Chloride; Mice; Mice, Knockout; Ovalbumin; Receptors, CCR10; Receptors, Chemokine; Respiratory Hypersensitivity; Transforming Growth Factor beta1

2007
Severity of obstructive airways disease by age 2 years predicts asthma at 10 years of age.
    Thorax, 2008, Volume: 63, Issue:1

    Topics: Age Factors; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Case-Control Studies; Child; Cohort Studies; Female; Follow-Up Studies; Humans; Infant; Lung Diseases, Obstructive; Male; Methacholine Chloride; Prognosis; Risk Factors; Severity of Illness Index

2008
Bronchial hyperreactivity in chronic obstructive bronchitis.
    The American review of respiratory disease, 1983, Volume: 127, Issue:4

    Topics: Bronchial Spasm; Bronchitis; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds

1983
A prospective longitudinal study of methacholine airway responsiveness as a predictor of pulmonary-function decline: the Normative Aging Study.
    American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:1

    Topics: Aging; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cohort Studies; Humans; Linear Models; Longitudinal Studies; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Predictive Value of Tests; Prospective Studies; Risk Factors; Spirometry; Time Factors

1995
Standardization of methacholine inhalation challenge by a reservoir method.
    Asian Pacific journal of allergy and immunology, 1994, Volume: 12, Issue:2

    Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Chronic Disease; Cough; Dose-Response Relationship, Drug; Female; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Nebulizers and Vaporizers; Reference Standards; Rhinitis, Allergic, Seasonal

1994
Airway responsiveness to methacholine, respiratory symptoms, and dust exposure levels in grain and flour mill workers in eastern France.
    American journal of industrial medicine, 1995, Volume: 27, Issue:6

    Topics: Adult; Air Pollutants, Occupational; Bronchial Provocation Tests; Case-Control Studies; Chronic Disease; Cross-Sectional Studies; Dust; Edible Grain; Flour; France; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Occupational Diseases; Regression Analysis; Respiration Disorders; Skin Tests; Smoking

1995
Chronic respiratory symptoms and airway responsiveness to methacholine are associated with eosinophilia in older men: the Normative Aging Study.
    The European respiratory journal, 1995, Volume: 8, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Bronchial Hyperreactivity; Bronchial Provocation Tests; Eosinophilia; Humans; Hypersensitivity; Longitudinal Studies; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Skin Tests

1995
Distribution of bronchial responsiveness in a general population: effect of sex, age, smoking, and level of pulmonary function.
    American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Child; Female; Humans; Italy; Longitudinal Studies; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Prospective Studies; Respiratory Function Tests; Rural Population; Sex Characteristics; Sex Factors; Smoking

1995
Inhalation of nitric oxide modulates adult human bronchial tone.
    The American review of respiratory disease, 1993, Volume: 148, Issue:6 Pt 1

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Airway Resistance; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Functional Residual Capacity; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Methemoglobinemia; Middle Aged; Nitric Oxide; Oxygen

1993
Bronchial reactivity and airflow obstruction in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1994, Volume: 53, Issue:8

    Topics: Adult; Aged; Arthritis, Rheumatoid; Bronchial Hyperreactivity; Female; Forced Expiratory Volume; Humans; Hypersensitivity, Immediate; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Prospective Studies; Respiratory Function Tests; Smoking

1994
Bronchial responsiveness and acute bronchodilator response in chronic obstructive pulmonary disease and diffuse panbronchiolitis.
    Thorax, 1994, Volume: 49, Issue:6

    Topics: Aged; Albuterol; Bronchial Provocation Tests; Bronchiolitis; Bronchoconstriction; Female; Forced Expiratory Volume; Humans; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged

1994
Duration of antigen-induced hyperresponsiveness in horses with allergic respiratory disease and possible links with early airway obstruction.
    Journal of veterinary pharmacology and therapeutics, 1993, Volume: 16, Issue:4

    Topics: Airway Obstruction; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Horse Diseases; Horses; Lung Diseases, Obstructive; Methacholine Chloride; Respiratory Function Tests

1993
Airway responsiveness to adenosine 5'-monophosphate in chronic obstructive pulmonary disease is determined by smoking.
    The American review of respiratory disease, 1993, Volume: 147, Issue:3

    Topics: Adenosine Monophosphate; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Smoking

1993
Asthmatic risk factors and bronchial reactivity in non-diagnosed asthmatic adults.
    European journal of epidemiology, 1995, Volume: 11, Issue:5

    Topics: Adult; Aged; Arizona; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Disease Progression; Disease Susceptibility; Female; Follow-Up Studies; Forecasting; Humans; Immunoglobulin E; Longitudinal Studies; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Respiratory Sounds; Risk Factors

1995
Effects of equine influenza and tetanus vaccination on pulmonary function in normal and chronic obstructive pulmonary disease affected horses.
    Equine veterinary journal, 1996, Volume: 28, Issue:2

    Topics: Animals; Antibodies, Fungal; Aspergillus fumigatus; Bronchoalveolar Lavage Fluid; CD4-CD8 Ratio; Horse Diseases; Horses; Immunoglobulin A; Immunoglobulin E; Immunoglobulin M; Influenza A virus; Lung; Lung Diseases, Obstructive; Methacholine Chloride; Tetanus Toxoid; Trachea; Vaccination; Vaccines, Combined; Vaccines, Inactivated; Viral Vaccines

1996
Influence of baseline airway calibre and pulmonary emphysema on bronchial responsiveness in patients with chronic obstructive pulmonary disease.
    Respiratory medicine, 1996, Volume: 90, Issue:6

    Topics: Aged; Bronchi; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Pulmonary Emphysema; Regression Analysis; Respiratory Function Tests

1996
The semi-proportional hazards model revisited: practical reparametrizations.
    Statistics in medicine, 1996, Aug-30, Volume: 15, Issue:16

    Topics: Adult; Aged; Bronchi; Bronchoconstrictor Agents; Data Interpretation, Statistical; Effect Modifier, Epidemiologic; Female; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Proportional Hazards Models; Respiratory Mechanics; Smoking

1996
Vital capacities in acute and chronic airway obstruction: dependence on flow and volume histories.
    The European respiratory journal, 1997, Volume: 10, Issue:6

    Topics: Acute Disease; Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Lung Volume Measurements; Methacholine Chloride; Middle Aged; Pulmonary Ventilation; Residual Volume; Vital Capacity

1997
The Lung Health Study.
    Current opinion in pulmonary medicine, 1996, Volume: 2, Issue:2

    Topics: Adult; Behavior Therapy; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; Chewing Gum; Follow-Up Studies; Forced Expiratory Volume; Humans; Ipratropium; Lung; Lung Diseases, Obstructive; Methacholine Chloride; Middle Aged; Motivation; Multicenter Studies as Topic; Nicotine; Placebos; Randomized Controlled Trials as Topic; Single-Blind Method; Smoking; Smoking Cessation

1996
Effect of a set stabled environmental control on pulmonary function and airway reactivity of COPD affected horses.
    Veterinary journal (London, England : 1997), 1998, Volume: 155, Issue:2

    Topics: Animals; Atropine; Horse Diseases; Horses; Housing, Animal; Lung Compliance; Lung Diseases, Obstructive; Methacholine Chloride; Reference Values; Respiration; Respiratory Function Tests

1998
Worsening of hypoxemia with nitric oxide inhalation during bronchospasm in humans.
    Respiration physiology, 1998, Volume: 112, Issue:1

    Topics: Administration, Inhalation; Adult; Asthma; Dose-Response Relationship, Drug; Female; Humans; Hypoxia; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Pulmonary Gas Exchange

1998
Cough threshold in patients with chronic obstructive pulmonary disease.
    Thorax, 1999, Volume: 54, Issue:1

    Topics: Adult; Aged; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cough; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Vital Capacity

1999
[Clinical evaluation and significance of measurement of airway hyperresponsiveness in COPD].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57, Issue:9

    Topics: Adult; Aged; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Contraindications; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Prognosis

1999
Compliance, hysteresis, and collapsibility of human small airways.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:4

    Topics: Adult; Aged; Biomechanical Phenomena; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Compliance; Female; Forced Expiratory Volume; Humans; In Vitro Techniques; Isoproterenol; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Muscle Relaxation; Muscle, Smooth; Pressure; Residual Volume; Total Lung Capacity; Vital Capacity

1999
IL-10 reduces grain dust-induced airway inflammation and airway hyperreactivity.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 88, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dust; Inflammation; Interleukin-10; Lipopolysaccharides; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Monokines; Neutrophil Infiltration; Respiratory Tract Diseases; RNA, Messenger; Zea mays

2000
Differences in airway responsiveness to acetaldehyde and methacholine in asthma and chronic bronchitis.
    The European respiratory journal, 2000, Volume: 15, Issue:2

    Topics: Acetaldehyde; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Bronchoconstrictor Agents; Diagnosis, Differential; Female; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Sensitivity and Specificity; Smoking

2000
Influence of lung parenchymal destruction on the different indexes of the methacholine dose-response curve in COPD patients.
    Chest, 2000, Volume: 117, Issue:4

    Topics: Administration, Inhalation; Adult; Aged; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Carbon Monoxide; Dose-Response Relationship, Drug; Forced Expiratory Volume; Humans; Lung Compliance; Lung Diseases, Obstructive; Methacholine Chloride; Middle Aged; Prognosis; Pulmonary Emphysema; Radiography

2000
Environmental exposure to air pollution and allergens and peak flow changes.
    The European respiratory journal, 2000, Volume: 16, Issue:1

    Topics: Adult; Aged; Air Pollutants; Allergens; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Flow Rates; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Nitrogen Dioxide; Ozone; Peak Expiratory Flow Rate; Pollen; Spores, Fungal

2000
Deep inspiration-induced bronchoprotection is stronger than bronchodilation.
    American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:3 Pt 1

    Topics: Adult; Airway Resistance; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Inhalation; Lung Diseases, Obstructive; Male; Methacholine Chloride; Risk Factors

2000
Borg scores before and after challenge with adenosine 5'-monophosphate and methacholine in subjects with COPD and asthma.
    The European respiratory journal, 2000, Volume: 16, Issue:3

    Topics: Adenosine Monophosphate; Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Dyspnea; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Smoking

2000
Endotoxin responsiveness and subchronic grain dust-induced airway disease.
    American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 280, Issue:2

    Topics: Actins; Acute Disease; Administration, Inhalation; Aerosols; Airway Resistance; Animals; Bronchoalveolar Lavage Fluid; Collagen; Crosses, Genetic; Disease Models, Animal; Dust; Endotoxins; Genetic Predisposition to Disease; Immunohistochemistry; Lung Diseases, Obstructive; Methacholine Chloride; Mice; Mice, Inbred C3H; Neutrophils; Pneumonia; Species Specificity; Zea mays

2001
Low-attenuation areas of the lungs on high-resolution computed tomography in asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2001, Volume: 38, Issue:5

    Topics: Administration, Inhalation; Aged; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin E; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Spirometry; Tomography, X-Ray Computed

2001
Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma.
    The Journal of allergy and clinical immunology, 2001, Volume: 108, Issue:5

    Topics: Adult; Age Factors; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Female; Forced Expiratory Volume; Humans; Linear Models; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Neutrophil Infiltration; Pulmonary Eosinophilia; Retrospective Studies; Sputum

2001
Methacholine responsiveness, smoking, and atopy as risk factors for accelerated FEV1 decline in male working populations.
    The American review of respiratory disease, 1992, Volume: 146, Issue:4

    Topics: Adult; Bronchial Hyperreactivity; Bronchial Provocation Tests; Forced Expiratory Volume; Humans; Hypersensitivity, Immediate; Longitudinal Studies; Lung Diseases, Obstructive; Male; Methacholine Chloride; Occupational Exposure; Predictive Value of Tests; Prevalence; Regression Analysis; Risk Factors; Smoking

1992
A discriminant analysis applied to methacholine bronchoprovocation testing improves classification of patients as normal, asthma, or COPD.
    Chest, 1992, Volume: 102, Issue:5

    Topics: Adult; Asthma; Bronchial Provocation Tests; Discriminant Analysis; Forced Expiratory Flow Rates; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Middle Aged; Predictive Value of Tests; Sensitivity and Specificity; Vital Capacity

1992
Respiratory symptoms as predictors of airways lability in an elderly population.
    Respiratory medicine, 1992, Volume: 86, Issue:1

    Topics: Aged; Aged, 80 and over; Albuterol; Bronchial Hyperreactivity; Female; Humans; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Predictive Value of Tests; Smoking

1992
Small airways dysfunction among non-smoking shipyard arc welders.
    British journal of industrial medicine, 1992, Volume: 49, Issue:6

    Topics: Adult; Bronchial Provocation Tests; Forced Expiratory Volume; Humans; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Nitrogen; Occupational Diseases; Spirometry; Total Lung Capacity; Welding

1992
Characteristics of bronchial hyperresponsiveness in chronic obstructive pulmonary disease and in asthma.
    The American review of respiratory disease, 1991, Volume: 143, Issue:6

    Topics: Asthma; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Histamine; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Osmosis; Peak Expiratory Flow Rate; Propranolol; Sensitivity and Specificity

1991
[Dependence of bronchial hyperreactivity on the initial value of airway resistance].
    Pneumologie (Stuttgart, Germany), 1990, Volume: 44 Suppl 1

    Topics: Airway Resistance; Bronchial Provocation Tests; Fenoterol; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds; Plethysmography, Whole Body; Respiratory Hypersensitivity

1990
Methacholine responsiveness among working populations. Relationship to smoking and airway caliber.
    The American review of respiratory disease, 1990, Volume: 142, Issue:6 Pt 1

    Topics: Adult; Airway Resistance; British Columbia; Bronchial Provocation Tests; Bronchoconstriction; Cross-Sectional Studies; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Occupations; Prevalence; Regression Analysis; Risk Factors; Skin Tests; Smoking

1990
[Allergy and bronchial hyperreactivity in chronic obstructive lung disease].
    Vutreshni bolesti, 1990, Volume: 29, Issue:4

    Topics: Asthma; Bronchi; Bronchial Provocation Tests; Female; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Respiratory Hypersensitivity; Skin Tests

1990
Effect of breathing pattern during inhalation challenge on the shape and position of the dose-response curve.
    Lung, 1989, Volume: 167, Issue:2

    Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Humans; Lung Diseases, Obstructive; Lung Volume Measurements; Male; Methacholine Chloride; Methacholine Compounds

1989
Smoking habit and bronchial reactivity in normal subjects. A population-based study.
    The American review of respiratory disease, 1989, Volume: 140, Issue:1

    Topics: Adolescent; Adult; Bronchi; Bronchial Provocation Tests; Cross-Sectional Studies; Female; Forced Expiratory Volume; Humans; Italy; Lung Diseases, Obstructive; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Regression Analysis; Smoking

1989
[Evaluation of inhalation provocation with methacholine--comparison of one second capacity and resistance].
    Wiener medizinische Wochenschrift. Supplement, 1989, Volume: 104

    Topics: Adolescent; Adult; Airway Resistance; Austria; Bronchial Provocation Tests; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Methacholine Compounds; Reference Values

1989
[Airway responsiveness measured by body plethysmograph connecting a circuit of an inhalation system of serially concentrated bronchoconstrictant].
    Nihon Kyobu Shikkan Gakkai zasshi, 1989, Volume: 27, Issue:12

    Topics: Acetylcholine; Administration, Inhalation; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Child; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds; Nebulizers and Vaporizers; Plethysmography, Whole Body

1989
[Nasal hyperreactivity. Pharmacodynamics].
    Anales espanoles de pediatria, 1985, Nov-30, Volume: 23, Issue:7

    Topics: Carbachol; Child; Child, Preschool; Humans; Ipratropium; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds; Nasal Mucosa; Nasal Provocation Tests; Parasympathetic Nervous System; Receptors, Cholinergic; Rhinitis

1985
Childhood asthma and adult lung function.
    The American review of respiratory disease, 1988, Volume: 138, Issue:1

    Topics: Adult; Aging; Asthma; Child; Female; Humans; Longitudinal Studies; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Methacholine Compounds; Prospective Studies; Respiratory Function Tests; Smoking

1988
The effect of bronchoalveolar lavage on bronchial responsiveness in patients with airflow obstruction.
    Chest, 1988, Volume: 93, Issue:2

    Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds; Middle Aged; Pulmonary Emphysema; Pulmonary Ventilation

1988
Inhibition of methacholine-induced bronchoconstriction in patients with chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1988, Volume: 137, Issue:2

    Topics: Aerosols; Airway Resistance; Bronchi; Bronchial Provocation Tests; Drug Evaluation; Forced Expiratory Volume; Humans; Isoproterenol; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds; Nebulizers and Vaporizers; Pulmonary Diffusing Capacity; Smoking; Spirometry

1988
[The sequential changes in respiratory resistance during the inhalation of cold air and bronchial hyperresponsiveness].
    Arerugi = [Allergy], 1988, Volume: 37, Issue:2

    Topics: Adult; Aged; Air; Airway Resistance; Bronchial Provocation Tests; Cold Temperature; Female; Humans; Lung Diseases, Obstructive; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Respiratory Hypersensitivity

1988
Increased in vitro histamine responses in human small airways smooth muscle from patients with chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1987, Volume: 135, Issue:3

    Topics: Bronchi; Dose-Response Relationship, Drug; Histamine; Humans; In Vitro Techniques; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds; Muscle, Smooth; Osmolar Concentration; Reference Values; SRS-A

1987
Airway responsiveness to histamine or methacholine: advances in measurement and interpretation.
    Respiration; international review of thoracic diseases, 1986, Volume: 50 Suppl 2

    Topics: Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Histamine; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds; Respiratory System

1986
Prediction of airway reactivity from responses to a standardized respiratory symptom questionnaire.
    The American review of respiratory disease, 1987, Volume: 135, Issue:4

    Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Humans; Lung Diseases, Obstructive; Male; Mass Screening; Methacholine Chloride; Methacholine Compounds; Middle Aged; Respiratory Sounds; Risk; Surveys and Questionnaires

1987
Airway reactivity in chronic obstructive pulmonary disease. Failure of in vivo methacholine responsiveness to correlate with cholinergic, adrenergic, or nonadrenergic responses in vitro.
    The American review of respiratory disease, 1985, Volume: 132, Issue:1

    Topics: Aged; Albuterol; Bronchi; Bronchial Provocation Tests; Colforsin; Diterpenes; Female; Forced Expiratory Volume; Humans; In Vitro Techniques; Lung Diseases, Obstructive; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Pneumonectomy

1985
The effects of acute bronchoconstriction on respiratory activity in patients with chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1985, Volume: 131, Issue:2

    Topics: Aged; Airway Resistance; Bronchial Provocation Tests; Bronchial Spasm; Carbon Dioxide; Humans; Hyperventilation; Lung Compliance; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds; Middle Aged; Pulmonary Gas Exchange; Respiration; Tidal Volume; Ventilation-Perfusion Ratio

1985
Respiratory pressure sensation. Relationship to changes in breathing pattern and PCO2 during acute increase in airway resistance in patients with chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1985, Volume: 132, Issue:6

    Topics: Airway Resistance; Bronchi; Carbon Dioxide; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds; Middle Aged; Partial Pressure; Plethysmography; Pressure; Respiration; Spirometry

1985