methacholine chloride has been researched along with Innate Inflammatory Response in 229 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (2.18) | 18.7374 |
| 1990's | 40 (17.47) | 18.2507 |
| 2000's | 92 (40.17) | 29.6817 |
| 2010's | 83 (36.24) | 24.3611 |
| 2020's | 9 (3.93) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J | 1 |
| Bossé, Y; Boucher, M; Brunet, D; Dufour-Mailhot, A; Fereydoonzad, L; Henry, C; Khadangi, F; Robichaud, A; Tremblay-Pitre, S | 1 |
| Henry, PJ; Landwehr, KR; Larcombe, AN; Mann, TS; Noble, PB; Shamsuddin, D; Wang, KCW | 1 |
| Chae, S; Choo, BK; Hwang, YH; Jang, S; Kim, HK; Kim, KM; Kim, SH; Kim, T; Kim, YH; Shim, KS; Song, HK; Yang, WK | 1 |
| Feng, Y; Li, L; Li, Z; Liu, L; Ma, S; Wang, J; Wang, X; Wang, Z; Yang, K; Zhu, Y; Zhu, Z | 1 |
| De Carvalho Bittencourt, M; Demoulin, B; Demoulin-Alexikova, S; Divaret-Chauveau, A; Foucaud, L; Le Cann, P; Loison, P; Mauny, F; Schweitzer, C; Teston, C | 1 |
| Kotaniemi-Syrjänen, A; Lindahl, H; Lohi, J; Mäkelä, MJ; Malmberg, LP; Malmström, K; Pelkonen, AS; Sarna, S | 1 |
| Contaifer, D; Dileepan, M; Ge, XN; Greenberg, YG; Ha, SG; Rao, SP; Rastle-Simpson, S; Sriramarao, P; Wijesinghe, DS | 1 |
| Cui, J; Dong, J; Dong, M; Qin, J; Tang, W; Teng, F; Wang, S; Wang, W; Wei, Y; Wuniqiemu, T; Zhu, X | 1 |
| Aronsson, P; Aydogdu, O; Carlsson, T; Gocun, PU; Winder, M | 1 |
| Berry, LJ; Bredin, A; Franklin, PJ; Janka, MA; Larcombe, AN; Mullins, BJ | 1 |
| Cardell, LO; Xu, Y | 1 |
| Eslami-Behroozi, M; Javan, M; Raoufy, MR | 1 |
| Carlsen, KH; Holm, AM; Sikkeland, LIB; Stang, J; Stensrud, T; Tufvesson, E | 1 |
| Alipour, MR; Aslani, MR; Ebrahimi, H; Keyhanmanesh, R | 1 |
| Bossé, Y; Brook, BS; Deschênes, L; Gazzola, M; Henry, C; Lortie, K; Mailhot-Larouche, S; Morissette, MC | 1 |
| Aierken, A; Xu, P | 1 |
| Delecaris, A; Gunst, SJ; Hatch, J; Jalou, H; Krupp, N; Praca, E; Slaven, J; Tepper, RS | 1 |
| Chen, CM; Chiang, BL; Chou, HC; Lin, SC | 1 |
| Domenico, J; Gelfand, EW; Joetham, A; Ning, F; Schedel, M; Takeda, K | 1 |
| Casola, A; Garofalo, RP; Ivanciuc, T; Sbrana, E | 1 |
| Bonta, PI; Chowdhury, S; Dijkhuis, A; Lutter, R; Ravi, A; Sterk, PJ | 1 |
| Choi, BS; Jee, HM; Kim, KE; Kim, KW; Lee, HH; Lee, YJ; Sohn, MH | 1 |
| Bacci, E; Bartoli, ML; Cianchetti, S; Costa, F; Dente, FL; Malagrinò, L; Novelli, F; Paggiaro, P; Vagaggini, B | 1 |
| Gauvreau, GM; Grasemann, H; Inman, MD; Khanna, N; North, ML; Scott, JA | 1 |
| Furuhata, M; Ichijo, H; Mizuguchi, J; Nakae, S; Sudo, K; Takada, E | 1 |
| Bailey, S; Bourke, JE; Donovan, C; Esposito, J; Ibrahim, ZA; Royce, SG; Tang, ML; Tran, J | 1 |
| Aguila, MB; Bargut, TC; Daleprane, JB; Ferreira, TP; Martins, MA; Silva, PM | 1 |
| Bastien, M; Boulet, LP; Gagnon-Audet, AA; Martin, J; Poirier, P; Simard, S; Turcotte, H | 1 |
| Hattori, T; Hizawa, N; Huang, SK; Isada, A; Konno, S; Nishimura, M; Shijubo, N; Shimizu, K; Taniguchi, N | 1 |
| de Arantes, AC; do Nascimento, CV; Ferreira, TP; Hogaboam, CM; Martins, MA; Olsen, PC; Puri, RK; Rocco, PR; Silva, PM; Trentin, PG | 1 |
| Balgoma, D; Billing, B; Daham, K; Dahlén, B; Dahlén, SE; FitzGerald, GA; Henriksson, E; James, A; Kupczyk, M; Lindeberg, A; Wheelock, CE | 1 |
| Gu, W; Mao, S; Shi, Y; Tan, Y | 1 |
| Alcorn, JF; Elloso, MM; Kolls, JK; Mandalapu, S; Manni, ML; Scheller, EV; Trudeau, JB; Wenzel, SE | 1 |
| Beppu, A; Broide, DH; Doherty, TA; Hoffman, HM; McGeough, MD; Miller, M; Mueller, JL; Niwa, M; Pena, CA; Rosenthal, P; Suzukawa, M; Tam, AB | 1 |
| Bergquist, M; Hanrieder, J; Hedenstierna, G; Hjoberg, J; Jonasson, S | 1 |
| Blackburn, MR; Dickey, BF; Eltzschig, HK; Evans, CM; Fletcher, AA; Harper, DN; Janssen, WJ; Kindrachuk, KN; Liptzin, DR; McElwee, MM; McGing, MA; Raclawska, DS; Roy, MG; Sanchez, E; Schwartz, DA; Ttofali, F; Tuvim, MJ; Williams, OW; Wynn, TA | 1 |
| Aggarwal, S; Creighton, J; Doran, SF; Emala, CW; Garantziotis, S; Komarova, S; Lazrak, A; Matalon, S; Stober, VP; Trempus, CS; Yu, Z | 1 |
| Perzanowski, MS; Yoo, Y | 1 |
| Gavett, SH; Kollarik, M; McAlexander, MA; Undem, BJ | 1 |
| Alexandre, EC; Antunes, E; Arantes-Costa, FM; Calixto, MC; Donato, J; Folli, F; Leiria, LOS; Martins, MA; Moura, RF; Prado, CM; Prado, MA; Prado, VF; Saad, MJA; Velloso, LA | 1 |
| Ducka-Kokalari, B; Gullipalli, D; Haczku, A; Miwa, T; Redai, IG; Sato, S; Song, WC; Wang, Y; Zangrilli, JG | 1 |
| Alving, K; Borres, MP; Gunnbjornsdottir, M; Högman, M; Janson, C; Malinovschi, A; Patelis, A | 1 |
| Britt, RD; Faksh, A; Kuipers, I; Martin, RJ; Pabelick, CM; Prakash, YS; Sieck, GC; Thompson, MA; Vogel, ER | 1 |
| Bartsch, JW; Chen, J; Deng, L; Dreymüller, D; Duan, Y; Jiang, X; Koller, G; Lin, F; Long, J; Luo, M; Mao, L; Müller, B; Wang, Y | 1 |
| Domvri, K; Fouka, E; Kontakioti, E; Kontakiotis, T; Papakosta, D; Porpodis, K; Zarogoulidis, K | 1 |
| Cho, KS; Mun, SJ; Park, HY; Park, MK; Roh, HJ; Yu, HS | 1 |
| Allard, B; Ano, S; Hamamoto, Y; Ishii, Y; Martin, JG; McGovern, TK; O'Sullivan, M; Panariti, A; Powell, WS; Yamamoto, M | 1 |
| Kukkonen, AK; Mäkelä, MJ; Malmberg, LP; Pelkonen, AS; Uotila, R | 1 |
| Aref, E; Eslami-Behroozi, M; Hajizadeh, S; Javan, M; Pazhoohan, S; Raoufy, MR; Zare, L | 1 |
| Backer, V; Barnes, PJ; Kharitonov, SA; Lund, TK; Pedersen, L | 1 |
| Anderson, SD; Kippelen, P | 1 |
| Allen, ND; Cockcroft, DW; Davis, BE | 1 |
| Corren, J | 1 |
| Hemilä, H | 1 |
| Freyschmidt, EJ; Mathias, CB; Oettgen, HC | 1 |
| Dagli, E; Demirel, GY; Ersu, R; Guran, T; Hekim, N; Karadag, B; Karakoc, F | 1 |
| De Vooght, V; Hoet, PH; Nemery, B; Vanoirbeek, JA | 1 |
| Chaudhary, D; Deng, B; Goldman, S; Ho, MW; Kasaian, M; Krane, CM; Mason, L; McDonald, CA; Mutyam, V; Pazdziorko, S; Williams, C | 1 |
| Adner, M; Dahlén, SE; Hjoberg, J; Jonasson, S; Neimert-Andersson, T; Ryrfeldt, A; Swedin, L; van Hage, M | 1 |
| Choi, BS; Jee, HM; Kim, KE; Kim, KW; Park, YH; Sohn, MH | 1 |
| Gosens, R; Halayko, AJ; Hiemstra, PS; Kolahian, S; Meurs, H; Nanninga, J; Ninaber, DK; Rabe, KF; Rieks, D; Zuyderduyn, S | 1 |
| Cataldo, DD; Crahay, C; Foidart, JM; Gueders, MM; Hacha, J; Louis, R; Noël, A; Paulissen, G; Quesada-Calvo, F; Tournoy, K; Van Hove, C | 1 |
| Berro, A; Casale, TB; Mehta, V; Romero, FA; Stokes, JR | 1 |
| Allen, GB; Bates, JH; Cloutier, ME; Irvin, CG; Larrabee, YC; Leclair, TR; von Reyn, J | 1 |
| Frascaroli, M; Moscato, G; Pala, G; Perfetti, L; Pignatti, P | 1 |
| Bullens, DM; Cadot, P; Ceuppens, JL; Meyts, I; Vanaudenaerde, B; Vanoirbeek, JA | 1 |
| Adner, M; Dahlén, SE; Ellis, R; Inman, M; Neimert-Andersson, T; Nilsson, G; Ryrfeldt, A; Swedin, L | 1 |
| Björnsson, E; Eriksson, BM; Hedenström, H; Högman, M; Janson, C; Lúdvíksdóttir, D; Venge, P | 1 |
| Agrawal, DK; Makinde, TO | 1 |
| Acouetey, DS; Bohadana, A; Demange, V; Michaely, JP; Paris, C; Tossa, P; Zmirou-Navier, D | 1 |
| Asano, T; Hasegawa, Y; Ito, S; Kume, H; Taki, F | 1 |
| Adler, KB; Crews, AL; Fischer, BM; Foster, WM; Potts, EN; Voynow, JA | 1 |
| Cleave, J; Gordon, JR; Town, J; Willson, PJ | 1 |
| Clynen, E; De Vooght, V; Haenen, S; Hoet, PH; Maes, E; Nemery, B; Schoofs, L; Vanoirbeek, JA | 1 |
| Bao, MJ; Cao, R; Chen, XP; Deng, YM; Dong, XW; He, JS; Jiang, JX; Li, FF; Xie, QM; Xie, YC; Yan, XF | 1 |
| Chu, X; Ci, X; Deng, X; Hua, S; Wei, D; Wei, M | 1 |
| Bao, ZS; Dong, XW; Guan, Y; Hong, L; Tan, GL; Xie, QM; Zheng, HS | 1 |
| Gauvreau, GM; Howie, K; Imaoka, H; Killian, KJ; O'Byrne, PM; Obminksi, GL; Strinich, T; Watson, RM | 1 |
| Fernández-Nieto, M; Madero, MF; Manso, L; Ruiz-García, M; Sastre, J | 1 |
| Ciprandi, G; Cirillo, I; Signori, A | 1 |
| Fehrenbach, H; Garn, H; Kerzel, S; Maier, RF; Preisser, K; Rogosch, T; Schroeder, HW; Wagner, J; Yildirim, AÖ; Zemlin, M | 1 |
| Butte, AJ; Eckart, MR; Galli, SJ; Morgan, AA; Mukai, K; Tsai, M; Yu, M | 1 |
| Bunn, JY; Dixon, AE; Forgione, PM; Garudathri, J; Griffes, LA; Irvin, CG; Kaminsky, DA; Poynter, ME; Pratley, RE; Raymond, D; Whittaker-Leclair, LA | 1 |
| Foster, MW; Michael Foster, W; Potts, EN; Que, LG; Yang, Z | 1 |
| Ahn, KS; Jang, HY; Jeong, H; Kim, SM; Kwon, OK; Lee, HK; Oh, SR; Yuk, JE | 1 |
| Chang, YS; Hsieh, MH; Jan, RL; Kao, HF; Li, PH; Lin, YL; Wang, JY; Yeh, KC | 1 |
| Carter, L; Gelfand, EW; Hicken, E; Jackson, L; Jia, Y; Robinson, J; Shin, YS; Shiraishi, Y; Takeda, K; Wang, M; Wright, AD | 1 |
| Oldenburg, PJ; Poole, JA; Sisson, JH | 1 |
| Fisher, T; Lougheed, MD; Turcotte, SE | 1 |
| Bramble, LA; Greenwood, KK; Harkema, JR; Jackson-Humbles, DN; LaPres, JJ; Proper, SP; Saini, Y; Wagner, JG | 1 |
| Cho, KA; Cho, YJ; Kang, JL; Lee, H; Park, JW; Sohn, JH; Suh, JW; Woo, SY | 1 |
| Bougault, V; Boulet, LP; Chakir, J; Couture, C; Joubert, P; Laviolette, M; Loubaki, L; Turmel, J | 1 |
| Cheng, C; Goh, FY; Guan, S; Leung, BP; Sethi, G; Shanmugam, MK; Upton, N; Wong, WS | 1 |
| Aggarwal, S; Agrawal, A; Ahmad, T; Ghosh, B; Kumar, M; Mabalirajan, U; Mukerji, M; Pattnaik, B; Singh, R; Singh, S | 1 |
| Fitzgerald, JM; Gauvreau, GM; He, JQ; Kam, SH; O'Byrne, PM; Ruan, J; Singh, A; Tebbutt, SJ | 1 |
| Boulet, LP; Martin, J; Poirier, P; Turcotte, H | 1 |
| Adner, M; Cardell, LO; Dahlén, SE; Kumlien Georén, S; Starkhammar, M; Swedin, L | 1 |
| Hershey, GK; Le Cras, TD; Mushaben, EM; Nichols, WC; Pauciulo, MW | 1 |
| Cohn, LA; DeClue, AE; Dodam, J; Guntur, V; Lee-Fowler, TM; Reinero, CR | 1 |
| Bucht, A; Jonasson, S; Koch, B; Wigenstam, E | 1 |
| Cruz, MJ; Morell, F; Muñoz, X; Roca, O; Sanchez-Vidaurre, S; Torres, F | 1 |
| Allegood, JC; Alvarez, SE; Conrad, D; Falanga, YT; Harikumar, KB; Milstien, S; Oskeritzian, CA; Price, MM; Ryan, JJ; Spiegel, S | 1 |
| Amatullah, H; Chow, CW; Cooper, J; Godri, K; Khanna, N; North, ML; Penton, PC; Scott, JA; Wang, X | 1 |
| Ko, JL; Ku, MS; Lee, SS; Lee, YT; Lu, KH; Lue, KH; Sheu, JN; Sun, HL | 1 |
| Barrett, EG; Royer, CM; Rudolph, K | 1 |
| Arimura, S; Kajikawa, S; Mashima, R; Nakae, S; Oda, H; Yamanashi, Y | 1 |
| Chen, FH; Chen, H; Chen, ZG; Ji, JZ; Li, HT; Zhang, TT; Zou, XL | 1 |
| Cochran, JR; Colasurdo, GN; Cua, B; Elidemir, O; Fullmer, J; Khan, AM; Larsen, GL; Xue, H | 1 |
| Akbari, O; Berry, G; Dekruyff, RH; Fathman, CG; Meyer, EH; Oh, JW; Seroogy, CM; Umetsu, DT | 1 |
| Dekan, G; Epstein, MM; Mojtabavi, N; Stingl, G | 1 |
| De Hoogh, M; Ellis, R; Gauldie, J; Inman, MD; Leigh, R; O'Byrne, PM; Southam, DS; Wattie, J | 1 |
| Baraldo, S; Castagnaro, A; Chetta, A; D'Ippolito, R; Del Donno, M; Foresi, A; Olivieri, D; Saetta, M; Testi, R; Zanini, A | 1 |
| Inami, M; Kamata, T; Kimura, M; Murata, K; Nakayama, T; Shimizu, C; Sugaya, K; Taniguchi, M; Wang, CR; Yamashita, M | 1 |
| Barraclough-Mitchell, H; Bassett, DJ; DeLorme, MP; Doyon-Reale, N; Gao, X | 1 |
| Chi, EY; Harlan, JM; Henderson, WR; Iwata, A; Nishio, K; Winn, RK | 1 |
| Hamid, Q; Nag, SS; Renzi, PM; Xu, LJ | 1 |
| Hwang, PH; Kim, JS; Kwak, YG; Lee, KS; Lee, YC; Song, CH; Yi, HK | 1 |
| Chin, K; Matsumoto, H; Mishima, M; Niimi, A; Takemura, M; Ueda, T | 1 |
| Fong, AM; Lawson, BL; Lefkowitz, RJ; Patel, DD; Savov, JD; Schwartz, DA; Walker, JK | 1 |
| Paré, PD | 1 |
| Barnes, PJ | 1 |
| Broide, DH; Cho, JY; Ikeda, RK; McElwain, K; McElwain, S; Miller, M; Nayar, J; Raz, E; Walker, L | 1 |
| Ghezzo, H; Lemière, C; Maghni, K; Malo, JL; Yuquan, W | 1 |
| Vita, JA | 1 |
| Befus, AD; Ebeling, C; Forsythe, P; Gordon, JR; Vliagoftis, H | 1 |
| Battistini, E; Defilippi, AC; Pecora, S; Rossi, GA; Sabatini, F; Sale, R; Silvestri, M | 1 |
| Baek, KJ; Broide, DH; Cho, JY; Han, JW; Lee, SY; McElwain, K; McElwain, S; Miller, M; Nayar, J; Raz, E; Rodriguez, M | 1 |
| Aronica, MA; Boothby, M; Goral, M; McCarthy, S; Mitchell, D; Sheller, JR; Swaidani, S | 1 |
| Collins, RA; Herbert, C; Kumar, RK; Sly, PD; Turner, DJ | 1 |
| Courbon, D; Ducimetière, P; Kony, S; Leynaert, B; Neukirch, C; Neukirch, F; Vervloet, D; Zureik, M | 1 |
| Cho, YS; Lee, EY; Lee, J; Lee, KU; Lee, TH; Moon, HB; Park, JY | 1 |
| Das, AM; Emmell, E; Giles-Komar, J; Griswold, DE; Li, J; Li, L; Petley, T; Shang, X; Shealy, D; Volk, A; Yang, G | 1 |
| Currie, GP; Lee, DK; Saha, S | 1 |
| Mustafa, SJ; Oldenburg, PJ | 1 |
| Ciprandi, G; Cirillo, I; Massolo, A; Passalacqua, G; Tosca, M; Vizzaccaro, A | 1 |
| Kondo, M; Nagai, A; Nakata, J; Nohara, M; Takemiya, T; Tamaoki, J; Yamagata, K | 1 |
| Choi, IW; Im, SY; Kim, JH; Kim, YS; Ko, HM; Lee, HK; Lee, JH; Lee, YC; Park, YM; You, HJ | 1 |
| Adcock, IM; Barnes, PJ; Essilfie-Quaye, S; Kelly, C; Kharitonov, SA; Maneechotesuwan, K; Meah, S | 1 |
| Gelfand, EW; Joetham, A; Koya, T; Masuda, ES; Matsubara, S; Miyahara, N; Pine, P; Swasey, CH; Takeda, K | 1 |
| Atkins, C; Colasurdo, GN; Elidemir, O; Fullmer, JJ; Khan, AM; Stark, JM | 1 |
| Carroll, MC; Dakhama, A; Gelfand, EW; Giclas, PC; Holers, VM; Joetham, A; Miyahara, N; Takeda, K; Taube, C; Thurman, JM | 1 |
| Foster, PS; Hansbro, N; Herbert, C; Kumar, RK; Siegle, JS; Yang, M | 1 |
| Fujimoto, K; Hanaoka, M; Honda, T; Koizumi, T; Kubo, K; Urushibata, K; Yamaguchi, S | 1 |
| Lipworth, BJ; Menzies, D; Nair, A | 1 |
| Bradbury, JA; Card, JW; Carey, MA; DeGraff, LM; Foley, JF; Graves, JP; Lih, FB; Moorman, MP; Morgan, DL; Zeldin, DC; Zhao, Y | 1 |
| Bradbury, JA; Card, JW; Carey, MA; Dakhama, A; Flake, GP; Gavett, SH; Gelfand, EW; Germolec, DR; Graves, JP; Haykal-Coates, N; Jacobs, ER; Korach, KS; Larsen, GL; Loader, JE; Moorman, MP; Voltz, JW; Walker, VR; Zeldin, DC; Zhu, D | 1 |
| Card, JW; Cook, DN; DeGraff, LM; Graham, GJ; Lira, SA; Wang, T; Whitehead, GS | 1 |
| Marchal, F; Schweitzer, C | 1 |
| Aesif, SW; Brown, A; Irvin, CG; Janssen-Heininger, YM; McGovern, T; Reynaert, NL; Wouters, EF | 1 |
| Bathoorn, E; Boezen, HM; Kerstjens, HA; Koeter, GH; Postma, DS; Slebos, DJ; van der Toorn, M; van Oosterhout, AJ | 1 |
| Bae, SJ; Choi, YD; Choy, HE; Kim, MK; Kim, SY; Kim, YR; Ko, YJ; Koh, JT; Koh, YI; Lee, SE; Nam, JH; Rhee, JH; Ryu, HJ | 1 |
| Guedes, AG; Jude, JA; Kannan, MS; Kita, H; Lund, FE; Paulin, J | 1 |
| Bleecker, ER; Boetticher, G; Brasier, AR; Busse, WW; Calhoun, WJ; Castro, M; Ju, H; Lee, C; Victor, S | 1 |
| Bates, JH; Cojocaru, A; Haverkamp, HC; Irvin, CG | 1 |
| Lee, LY; Lin, RL; Wiggers, ME; Zhang, G | 1 |
| Ghosh, B; Mabalirajan, U; Ram, A; Singh, SK; Singh, VP | 1 |
| Burton, MD; McKenzie, R; Royce, SG; Tang, ML | 1 |
| Boulet, LP; Boutet, M; Carrier, G; Laviolette, M; Turcotte, H | 1 |
| Dusser, DJ; Lacronique, JG; Le Cae, A; Peiffer, C; Roisman, GL | 1 |
| Fushimi, K; Ikezawa, K; Iwasaki, H; Kaminuma, O; Kikkawa, H; Matsubara, S; Shimazu, N | 1 |
| DiCosmo, BF; Elias, JA; Flavell, RA; Geba, GP; Picarella, D; Rankin, JA; Stripp, BR; Whitsett, JA | 1 |
| Fujimura, M; Matsuda, T; Mizuhashi, K; Saito, M; Songür, N; Xiu, QY | 1 |
| Abdul-Salaam, S; Folinsbee, LJ; Harder, S; Horstman, DH; Ives, PJ; Kehrl, HR | 1 |
| Barbee, RA; Bertorelli, G; Chetta, A; Consigli, GF; Del Donno, M; Foresi, A; Olivieri, D; Pesci, A | 1 |
| Albert, RK; Chi, EY; Chiang, GK; Eriksen, P; Henderson, WR; Jonas, M; Jones, F; Lamm, WJ; Lewis, DB; Tien, YT; Zhang, Y | 1 |
| Busse, WW; Castleman, WL; Lemanske, RF; McAllister, PK; Sorkness, RL; Uhl, EW | 1 |
| Cernadas, M; Christiani, DC; De Sanctis, GT; Donovan, C; Finn, PW; Katona, I; Kobzik, L; Krinzman, SJ; Listman, J; Mark, D; Nassr, K; Perkins, DL; Wang, Y | 1 |
| Bettinger, CM; Kraft, M; Martin, RJ; Wenzel, SE | 1 |
| Dreborg, S; Ferdousi, HA | 1 |
| Gudbjörnsson, B; Stålenheim, G | 1 |
| Bradley, KL; Gelfand, EW; Hamelmann, E; Schwarze, J; Takeda, K | 1 |
| Bamford, TL; Johns, DP; Liakakos, P; Snell, GI; Walters, EH; Ward, C; Williams, TJ | 1 |
| Fukushima, Y; Hoshino, M; Nakamura, Y; Shin, Z | 1 |
| Bell, FP; Brashler, JR; Chin, JE; Fidler, SF; Griffin, RL; Hatfield, CA; Kolbasa, KP; Mobley, JL; Richards, IM; Shull, KL; Winterrowd, GE | 1 |
| Ballardini, L; Bridge, P; Ind, PW; Migliori, GB; Neri, M; Pisati, P; Sharara, A; Spanevello, A | 1 |
| Aris, RM; Balmes, JR; Chen, LL; Christian, D; Ferrando, R; Finkbeiner, W; Hearne, PQ; Kelly, T; Scannell, C; Tager, IB; Welch, B | 1 |
| Cox, C; Frampton, MW; Morrow, PE; Speers, DM; Torres, A; Tsai, Y; Utell, MJ; Voter, KZ; Whitin, JC | 1 |
| Gibson, PG; Saltos, N; Scott, J; Sewell, W; Woolley, K; Zlatic, K | 1 |
| Caramori, M; Chapman, KR; Gutierrez, C; McClean, PA; Silkoff, PE; Slutsky, AS; Zamel, N | 1 |
| Fujii, T; Hirata, K; Kanazawa, H; Kudoh, S; Shoji, S; Yoshikawa, J; Yoshikawa, T | 1 |
| Graham, BS; Johnson, JE; Mitchell, DB; Peebles, RS; Sheller, JR | 1 |
| Berry, G; DeKruyff, RH; Hansen, G; Umetsu, DT | 1 |
| Bel, EH; Sont, JK; Sterk, PJ; van Krieken, JH; Vandenbroucke, JP; Willems, LN | 1 |
| Abboud, R; Chan, H; Chan-Yeung, M; Dittrick, M; Obata, H | 1 |
| Bice, DE; Collie, DD; Lipscomb, MF; Lyons, CR; Wilder, JA; Wilson, BS | 1 |
| Barisione, G; Brusasco, V; Crimi, E; Pellegrino, R; Rodarte, JR; Spanevello, A | 1 |
| Barnes, PJ; Horváth, I | 1 |
| Dahlén, B; Eklund, A; Grunewald, J; Lensmar, C; Prieto, J; Roquet, A | 1 |
| Brahim, JJ; Hiemstra, PS; Hiltermann, JT; Lapperre, TS; Sont, JK; Steerenberg, PA; Sterk, PJ; Stolk, J; van Bree, L | 1 |
| Quinn, TJ; Schwartz, DA; Taylor, S; Wohlford-Lenane, CL | 1 |
| Dahl, R; Jensen, EJ; Steffensen, F | 1 |
| Holt, PG; Sly, PD; Tulić, MK; Wale, JL | 1 |
| Borish, L; Dakhama, A; Gelfand, EW; Joetham, A; Jordana, M; Kanehiro, A; Larsen, GL; Loader, J; Mäkelä, MJ; Xing, Z | 1 |
| Amayasu, H; Ebana, S; Hasegawa, H; Ishizaki, Y; Nakabayashi, M; Nakagawa, H; Nishikawa, T; Shoji, T; Yamamoto, Y; Yoshida, S | 1 |
| Fan, M; Justice, JP; Mustafa, J; Shibata, Y; Sur, S; Van Scott, MR | 1 |
| Broide, DH; Castaneda, D; Nayar, J; Sriramarao, P; Stachnick, G | 1 |
| Belda, J; Casan, P; Giner, J; Sanchis, J | 1 |
| Halldén, G; Hedlin, G; Hellman, C; Lönnkvist, K; Lundahl, J | 1 |
| Chu, HW; Harbeck, RJ; Honour, JM; Martin, RJ | 1 |
| Boushey, HA; Cherniack, RM; Chinchilli, VM; Craig, TJ; Drazen, JM; Fahy, JV; Fish, JE; Ford, JG; Israel, E; Kraft, M; Lazarus, SC; Lemanske, RF; Martin, RJ; Mauger, EA; McLean, D; Peters, SP; Sorkness, C; Szefler, SJ | 1 |
| Fiscus, LC; Steeber, DA; Tang, ML; Tedder, TF; Van Herpen, J | 1 |
| Cockcroft, DW | 1 |
| de Reus, DM; Kauffman, HF; Kerstjens, HA; Koëter, GH; Meijer, RJ; Postma, DS; Van Den Berge, M | 2 |
| Broide, DH; Castaneda, D; Cho, JY; Condon, T; Kim, J; Miller, M; Muller, WA; Nayar, J; Roman, M; Sriramarao, P; Sung, KL | 1 |
| Gauvreau, GM; Inman, MD; Lutsky, BN; O'Byrne, PM; Rerecich, T; Stryszak, P; Watson, RM | 1 |
| Barrett, EG; Bice, DE; Espindola, TM; Harrod, KS; Rosenberger, CL; Tesfaigzi, Y; Wang, SZ | 1 |
| Chiang, BL; Hong, RL; Ku, PH; Lai, YL; Lee, YL; Wu, YL; Ye, YL; Yu, CI | 1 |
| Lefort, J; Singer, M; Vargaftig, BB | 1 |
| Burgaud, JL; Del Soldato, P; Oudart, N; Tallet, D | 1 |
| Folkerts, G; Habernickel, J; Muijsers, RB; Nijkamp, FP; Postma, DS; van der Veeken, A | 1 |
| Larsson, BM; Larsson, K; Malmberg, P; Palmberg, L | 1 |
| Fozard, JR; Hannon, JP; Mazzoni, L; Rondeau, C; Tigani, B | 1 |
| Guido, P; Salerno, FG; Spanevello, A | 1 |
| Bates, JH; Irvin, CG; Tomioka, S | 1 |
| Balbo, A; Brusasco, V; Crimi, E; Miadonna, A; Milanese, M; Rossi, GA | 1 |
| Larsen, GL | 1 |
| Gundel, RH; Letts, LG; Wegner, CD | 1 |
| Bethel, RA; Cherniack, RM; Larsen, GL; Smith, HR; Voelkel, NF; Wenzel, SE; Westcott, JY | 1 |
| Bonta, I; De Jongste, J; Jongejan, R; Kerrebijn, K; Raatgeep, R; Stijnen, T | 1 |
| Brusasco, V; Crimi, E; Gianiorio, P; Lantero, S; Rossi, GA | 1 |
| Bertorelli, G; Chetta, A; Foresi, A; Olivieri, D; Pesci, A | 1 |
| Bonta, IL; de Jongste, JC; Jongejan, RC; Kerrebijn, KF; Raatgeep, RC; Stijnen, T | 1 |
| Collins, JV; Jeffery, PK; Kay, AB; Nelson, FC; Wardlaw, AJ | 1 |
| Boschetto, P; Bruchi, O; Cappellazzo, G; Fabbri, LM; Mapp, CE; Milani, GF; Pivirotto, F; Zocca, E | 1 |
| Bigby, BG; Boushey, HA; Goetzl, EJ; Holtzman, MJ; Leikauf, GD; Nadel, JA; Seltzer, J; Stulbarg, M; Ueki, IF | 1 |
| Hargreave, FE; Kirby, JG; O'Byrne, PM; Ramsdale, EH | 1 |
| Hargreave, FE; O'Byrne, PM; Ramsdale, EH | 1 |
9 review(s) available for methacholine chloride and Innate Inflammatory Response
| Article | Year |
|---|---|
Airway injury as a mechanism for exercise-induced bronchoconstriction in elite athletes.
Topics: Adrenergic beta-Agonists; Asthma, Exercise-Induced; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents; Capillary Permeability; Eicosanoids; Epithelial Cells; Exercise; Humans; Inflammation; Mast Cells; Methacholine Chloride; Muscle, Smooth; Sports | 2008 |
Small airways disease in asthma.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Aerosols; Airway Resistance; Asthma; Bronchioles; Bronchoconstrictor Agents; Eosinophils; Humans; Inflammation; Lymphocytes; Methacholine Chloride; Pulmonary Alveoli; Tomography, X-Ray Computed | 2008 |
Cough variant asthma: lessons learned from deep inspirations.
Topics: Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Cough; Eosinophils; Humans; Inflammation; Inhalation; Methacholine Chloride | 2012 |
Airway hyperresponsiveness in asthma: geometry is not everything!
Topics: Asthma; Biomechanical Phenomena; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Humans; Inflammation; Methacholine Chloride; Muscle, Smooth; Reproducibility of Results; Respiratory Mucosa; Severity of Illness Index | 2003 |
Cytokine-directed therapies for the treatment of chronic airway diseases.
Topics: Adrenal Cortex Hormones; Animals; Asthma; Chemokines; Cytokines; Humans; Inflammation; Interferons; Interleukin-10; Interleukin-12; Interleukin-13; Interleukin-4; Interleukin-5; Interleukin-9; Methacholine Chloride; Models, Biological; Neutrophils; Pulmonary Disease, Chronic Obstructive; Th2 Cells; Time Factors | 2003 |
Nitric oxide and vascular reactivity in African American patients with hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Black or African American; Brachial Artery; Carbazoles; Carotid Arteries; Carvedilol; Coronary Vessels; Drug Resistance; Endothelium; Glucose-6-Phosphatase; Humans; Hypertension; Inflammation; Isoproterenol; Methacholine Chloride; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroglycerin; Nitroprusside; Propanolamines; Prosencephalon; Racial Groups; Regional Blood Flow; Risk Factors; Vascular Resistance; White People | 2003 |
Non-invasive measurement of airway inflammation in asthma.
Topics: Adenosine Monophosphate; Asthma; Biomarkers; Breath Tests; Bronchial Hyperreactivity; Eosinophil Cationic Protein; Eosinophils; Exercise; Humans; Inflammation; Leukotrienes; Mannitol; Methacholine Chloride; Nitric Oxide | 2006 |
Tidal breathing affects airway responsiveness to methacholine.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Humans; Inflammation; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Tidal Volume | 2001 |
Asthma and the role of inflammation.
Topics: Airway Resistance; Asthma; Humans; Inflammation; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Occupational Diseases; Seasons | 1986 |
29 trial(s) available for methacholine chloride and Innate Inflammatory Response
| Article | Year |
|---|---|
Airway hyperresponsiveness, remodeling and inflammation in infants with wheeze.
Topics: Airway Remodeling; Asthma; Eosinophils; Female; Humans; Infant; Inflammation; Male; Methacholine Chloride; Muscle, Smooth; Respiratory Sounds | 2020 |
Influence of cardiac dysfunction and systemic inflammation on pulmonary function and airway responsiveness in obese subjects.
Topics: Adult; Aged; Asthma; Blood Glucose; Bronchoconstrictor Agents; C-Reactive Protein; Female; Heart Diseases; Heart Rate; Humans; Inflammation; Lipids; Male; Methacholine Chloride; Middle Aged; Natriuretic Peptide, Brain; Obesity; Respiratory Function Tests | 2013 |
Effects of selective COX-2 inhibition on allergen-induced bronchoconstriction and airway inflammation in asthma.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Eosinophils; Etoricoxib; Female; Forced Expiratory Volume; Humans; Inflammation; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Prostaglandins; Pyridines; Sputum; Sulfones | 2014 |
Double-blind placebo-controlled challenge showed that peanut oral immunotherapy was effective for severe allergy without negative effects on airway inflammation.
Topics: Administration, Oral; Adolescent; Bronchial Provocation Tests; Child; Desensitization, Immunologic; Double-Blind Method; Female; Humans; Inflammation; Male; Methacholine Chloride; Peanut Hypersensitivity; Young Adult | 2017 |
Withdrawal of inhaled steroids in children with non-cystic fibrosis bronchiectasis.
Topics: Administration, Inhalation; Adolescent; Apoptosis; Biomarkers; Bronchial Hyperreactivity; Bronchiectasis; Child; Female; Glucocorticoids; Humans; Inflammation; Male; Methacholine Chloride; Neutrophils; Sputum; Substance Withdrawal Syndrome | 2008 |
Time-dependent effects of inhaled corticosteroids on lung function, bronchial hyperresponsiveness, and airway inflammation in asthma.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Anti-Allergic Agents; Anti-Inflammatory Agents; Asthma; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Hydrogen-Ion Concentration; Inflammation; Lung; Male; Methacholine Chloride; Middle Aged; Mometasone Furoate; Nitrates; Nitric Oxide; Pregnadienediols; Young Adult | 2009 |
Airway remodeling and inflammation in competitive swimmers training in indoor chlorinated swimming pools.
Topics: Airway Remodeling; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cell Count; Chlorine; Eosinophils; Female; Humans; Inflammation; Male; Mast Cells; Methacholine Chloride; Mucins; Neutrophils; Nitric Oxide; Skin Tests; Spirometry; Swimming; Swimming Pools; T-Lymphocytes; Young Adult | 2012 |
Peripheral blood gene expression changes during allergen inhalation challenge in atopic asthmatic individuals.
Topics: Adult; Allergens; Asthma; Blood; Bronchial Provocation Tests; Cell Movement; Down-Regulation; Eukaryotic Initiation Factor-2; Female; Forced Expiratory Volume; Gene Expression Profiling; Globins; Hemoglobins; Humans; Inflammation; Interferons; Male; Methacholine Chloride; Middle Aged; Oligonucleotide Array Sequence Analysis; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA; Signal Transduction; Up-Regulation; Young Adult | 2012 |
Effect of bariatric surgery on airway response and lung function in obese subjects with asthma.
Topics: Adult; Anti-Asthmatic Agents; Asthma; Bariatric Surgery; Body Mass Index; Bronchial Provocation Tests; Bronchoconstrictor Agents; C-Reactive Protein; Female; Humans; Inflammation; Male; Methacholine Chloride; Middle Aged; Obesity, Morbid; Prospective Studies; Respiratory Mechanics; Weight Loss; Young Adult | 2012 |
Vascular component of airway remodeling in asthma is reduced by high dose of fluticasone.
Topics: Administration, Inhalation; Administration, Topical; Adolescent; Adult; Androstadienes; Anti-Inflammatory Agents; Asthma; Basement Membrane; Biopsy; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Double-Blind Method; Female; Fluticasone; Glucocorticoids; Humans; Inflammation; Male; Methacholine Chloride; Time Factors | 2003 |
Formoterol attenuates neutrophilic airway inflammation in asthma.
Topics: Adult; Asthma; Bronchodilator Agents; Double-Blind Method; Ethanolamines; Female; Forced Expiratory Volume; Formoterol Fumarate; Humans; Inflammation; Male; Methacholine Chloride; Middle Aged; Neutrophils; Nitric Oxide; Respiratory Function Tests; Vital Capacity | 2005 |
Characteristics of asthma resistant to moderate dose inhaled corticosteroid treatment on bronchial hyperresponsiveness.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Androstadienes; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Eosinophils; Female; Fluticasone; Forced Expiratory Volume; Humans; Inflammation; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Respiratory Function Tests | 2006 |
Anti-inflammatory effects of inhaled carbon monoxide in patients with COPD: a pilot study.
Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Carbon Monoxide; Eosinophils; Female; Forced Expiratory Volume; Health Status; Humans; Inflammation; Lung; Male; Methacholine Chloride; Middle Aged; Pilot Projects; Pulmonary Disease, Chronic Obstructive; Sputum | 2007 |
Perception of bronchial obstruction in asthmatic patients. Relationship with bronchial eosinophilic inflammation and epithelial damage and effect of corticosteroid treatment.
Topics: Adrenal Cortex Hormones; Adult; Aged; Asthma; Bradykinin; Bronchi; Bronchoconstriction; Eosinophils; Epithelium; Female; Humans; Inflammation; Male; Methacholine Chloride; Middle Aged; Perception | 1995 |
The effect of salmeterol on nocturnal symptoms, airway function, and inflammation in asthma.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Blood Proteins; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Bronchodilator Agents; Bronchoscopy; Cell Count; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Eosinophil Granule Proteins; Eosinophils; Female; Follow-Up Studies; Forced Expiratory Volume; Glycoproteins; Humans; Inflammation; Inflammation Mediators; Leukotriene B4; Lung; Lysophospholipase; Male; Methacholine Chloride; Placebos; Ribonucleases; Salmeterol Xinafoate; Sleep; Spirometry; Thromboxane B2 | 1997 |
Anti-inflammatory drugs do not alleviate bronchial hyperreactivity in Sjögren's syndrome.
Topics: Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Budesonide; Cromolyn Sodium; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Inflammation; Methacholine Chloride; Middle Aged; Pregnenediones; Prospective Studies; Sjogren's Syndrome | 1997 |
Effects of ketotifen on symptoms and on bronchial mucosa in patients with atopic asthma.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Anti-Allergic Agents; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asthma; Biopsy; Blood Proteins; Bronchi; Bronchial Provocation Tests; Bronchoscopy; Cytarabine; Double-Blind Method; Doxorubicin; Eosinophil Granule Proteins; Female; Forced Expiratory Volume; Humans; Immunohistochemistry; Inflammation; Ketotifen; Leukocyte Elastase; Male; Methacholine Chloride; Middle Aged; Peak Expiratory Flow Rate; Ribonucleases; T-Lymphocytes | 1997 |
Effects of ozone on normal and potentially sensitive human subjects. Part II: Airway inflammation and responsiveness to ozone in nonsmokers and smokers.
Topics: Adolescent; Adult; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Data Interpretation, Statistical; Double-Blind Method; Female; Flow Cytometry; Forced Expiratory Volume; Humans; Inflammation; Interleukin-6; Interleukin-8; Lung; Macrophages, Alveolar; Male; Mast Cells; Methacholine Chloride; Ozone; Physical Exertion; Reactive Oxygen Species; Respiratory Mechanics; Smoking; Spirometry; Therapeutic Irrigation; Time Factors; Vital Capacity | 1997 |
Exhaled nitric oxide and bronchial reactivity during and after inhaled beclomethasone in mild asthma.
Topics: Administration, Inhalation; Adult; Asthma; Beclomethasone; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cross-Over Studies; Female; Forced Expiratory Volume; Humans; Inflammation; Male; Methacholine Chloride; Nitric Oxide; Vital Capacity | 1998 |
Severity of exercise-induced bronchoconstriction is related to airway eosinophilic inflammation in patients with asthma.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Eosinophils; Exercise; Female; Humans; Inflammation; Male; Methacholine Chloride; Severity of Illness Index; Spirometry; Sputum; Statistics, Nonparametric | 1998 |
Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. The AMPUL Study Group.
Topics: Administration, Inhalation; Administration, Topical; Adult; Anti-Inflammatory Agents; Asthma; Biopsy; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchodilator Agents; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Inflammation; Male; Methacholine Chloride; Peak Expiratory Flow Rate; Practice Guidelines as Topic; Prospective Studies; Single-Blind Method; Steroids | 1999 |
Airway responsiveness to methacholine: effects of deep inhalations and airway inflammation.
Topics: Administration, Inhalation; Adolescent; Adult; Airway Resistance; Asthma; Bronchoconstrictor Agents; Cell Count; Dose-Response Relationship, Drug; Eosinophils; Female; Forced Expiratory Volume; Humans; Inflammation; Lung Volume Measurements; Male; Methacholine Chloride; Middle Aged; Plethysmography; Residual Volume; Respiration; Sputum | 1999 |
Ozone-induced inflammation assessed in sputum and bronchial lavage fluid from asthmatics: a new noninvasive tool in epidemiologic studies on air pollution and asthma.
Topics: Adult; Asthma; Biomarkers; Blood Proteins; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Inflammation; Interleukin-8; Leukocyte Count; Leukocyte Elastase; Male; Methacholine Chloride; Ozone; Placebos; Ribonucleases; Sputum | 1999 |
Clarithromycin suppresses bronchial hyperresponsiveness associated with eosinophilic inflammation in patients with asthma.
Topics: Adult; Asthma; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Clarithromycin; Cross-Over Studies; Eosinophil Granule Proteins; Eosinophilia; Female; Forced Expiratory Volume; Humans; Inflammation; Inflammation Mediators; Male; Methacholine Chloride; Middle Aged; Ribonucleases; Sputum | 2000 |
Eosinophil markers in blood, serum, and urine for monitoring the clinical course in childhood asthma: impact of budesonide treatment and withdrawal.
Topics: Adolescent; Anti-Asthmatic Agents; Antigens, CD; Asthma; Biomarkers; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Budesonide; Child; Disease Progression; Double-Blind Method; Eosinophil Granule Proteins; Eosinophil Peroxidase; Eosinophil-Derived Neurotoxin; Eosinophils; Female; Forced Expiratory Volume; Humans; Inflammation; Leukocyte Count; Male; Membrane Glycoproteins; Methacholine Chloride; Peroxidase; Peroxidases; Ribonucleases; Skin Tests; Spirometry; Tetraspanin 29 | 2001 |
Safety and reproducibility of sputum induction in asthmatic subjects in a multicenter study.
Topics: Aged; Asthma; Biomarkers; Blood Proteins; Bronchial Provocation Tests; Bronchoconstrictor Agents; Eosinophil Granule Proteins; Eosinophils; Female; Forced Expiratory Volume; Humans; Inflammation; Leukocyte Count; Male; Methacholine Chloride; Predictive Value of Tests; Ribonucleases; Serine Endopeptidases; Severity of Illness Index; Sputum; Tryptases | 2001 |
PC(20) adenosine 5'-monophosphate is more closely associated with airway inflammation in asthma than PC(20) methacholine.
Topics: Adenosine Monophosphate; Adolescent; Adult; Asthma; Breath Tests; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Eosinophils; Female; Forced Expiratory Volume; Humans; Inflammation; Linear Models; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Predictive Value of Tests; Sputum | 2001 |
Dose-dependent effects of inhaled mometasone furoate on airway function and inflammation after allergen inhalation challenge.
Topics: Administration, Inhalation; Adolescent; Adult; Airway Resistance; Allergens; Anti-Inflammatory Agents; Asthma; Bronchoconstrictor Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Eosinophils; Female; Forced Expiratory Volume; Humans; Inflammation; Male; Methacholine Chloride; Middle Aged; Mometasone Furoate; Pregnadienediols; Severity of Illness Index; Sputum; Time Factors; Treatment Outcome | 2001 |
Corticosteroid-induced improvement in the PC20 of adenosine monophosphate is more closely associated with reduction in airway inflammation than improvement in the PC20 of methacholine.
Topics: Adenosine Monophosphate; Adult; Androstadienes; Anti-Inflammatory Agents; Asthma; Female; Fluticasone; Forced Expiratory Volume; Glucocorticoids; Humans; Inflammation; Male; Methacholine Chloride; Multivariate Analysis; Prednisone | 2001 |
191 other study(ies) available for methacholine chloride and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature | 2010 |
Effects of airway smooth muscle contraction and inflammation on lung tissue compliance.
Topics: Airway Resistance; Animals; Inflammation; Lipopolysaccharides; Lung; Lung Compliance; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Muscle Contraction; Respiratory Mechanics | 2022 |
Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation, and airways hyperresponsiveness in mice exposed to house dust mite extract.
Topics: Adenosine Triphosphate; Allergens; Animals; Asthma; Azithromycin; Disease Models, Animal; Inflammation; Interleukin-13; Metaplasia; Methacholine Chloride; Mice; Mucins; Mucus; Pyroglyphidae | 2022 |
Ethanol extract of Veronica persica ameliorates house dust mite-induced asthmatic inflammation by inhibiting STAT-3 and STAT-6 activation.
Topics: Animals; Asthma; Cytokines; Ethanol; Immunoglobulin E; Inflammation; Lung; Methacholine Chloride; Mice; Pyroglyphidae; Veronica | 2022 |
A retro-inverso modified peptide alleviated ovalbumin-induced asthma model by affecting glycerophospholipid and purine metabolism of immune cells.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Immunoglobulin E; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Ovalbumin; Purines | 2023 |
Early exposure to farm dust in an allergic airway inflammation rabbit model: Does it affect bronchial and cough hyperresponsiveness?
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cough; Dust; Endotoxins; Farms; Immunoglobulin E; Inflammation; Methacholine Chloride; Ovalbumin; Rabbits | 2023 |
Pulmonary delivery of ORMDL3 short hairpin RNA - a potential tool to regulate allergen-induced airway inflammation.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Inflammation; Lung; Male; Membrane Proteins; Methacholine Chloride; Mice; Mice, Knockout; Mice, Transgenic; Pulmonary Eosinophilia; Respiratory Hypersensitivity; RNA Interference; RNA, Small Interfering | 2020 |
TMT-based quantitative proteomics reveals suppression of SLC3A2 and ATP1A3 expression contributes to the inhibitory role of acupuncture on airway inflammation in an OVA-induced mouse asthma model.
Topics: Acupuncture Therapy; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Fusion Regulatory Protein 1, Heavy Chain; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Proteomics; Respiratory Hypersensitivity; Sodium-Potassium-Exchanging ATPase | 2021 |
Prostate-to-bladder cross-sensitization in a model of zymosan-induced chronic pelvic pain syndrome in rats.
Topics: Animals; Cholinergic Agonists; Chronic Pain; Inflammation; Lower Urinary Tract Symptoms; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Pelvic Pain; Prostate; Prostatitis; Purinergic Agonists; Rats; Urinary Bladder; Urinary Bladder, Overactive; Urination; Zymosan | 2021 |
The effects of electronic cigarette aerosol exposure on inflammation and lung function in mice.
Topics: Aerosols; Airway Resistance; Animals; Body Weight; Elasticity; Electronic Nicotine Delivery Systems; Female; Functional Residual Capacity; Gas Chromatography-Mass Spectrometry; Inflammation; Inflammation Mediators; Lung; Methacholine Chloride; Mice, Inbred BALB C; Organ Size; Plethysmography; Respiratory Hypersensitivity; Smoking; Thorax | 2017 |
Long-term nicotine exposure dampens LPS-induced nerve-mediated airway hyperreactivity in murine airways.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Collagen; Electric Stimulation; Female; Inflammation; Lipopolysaccharides; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Nerve Tissue; Nicotine; Organ Culture Techniques; Respiratory Mechanics; Tetrodotoxin; Time Factors; Toll-Like Receptor 4; Trachea | 2017 |
Effect of airway remodeling and hyperresponsiveness on complexity of breathing pattern in rat.
Topics: Airway Remodeling; Animals; Asthma; Bronchoconstrictor Agents; Disease Models, Animal; Inflammation; Male; Methacholine Chloride; Random Allocation; Rats, Sprague-Dawley; Respiration; Respiratory Hypersensitivity; Specific Pathogen-Free Organisms | 2018 |
The Role of Airway Inflammation and Bronchial Hyperresponsiveness in Athlete's Asthma.
Topics: Adolescent; Adult; Asthma, Exercise-Induced; Athletes; Bronchial Hyperreactivity; Bronchial Provocation Tests; Case-Control Studies; Cross-Sectional Studies; Female; Forced Expiratory Volume; Humans; Inflammation; Interleukin-8; Male; Methacholine Chloride; Skiing; Sputum; Swimming; Young Adult | 2018 |
Effects of Diet-Induced Obesity on Tracheal Responsiveness to Methacholine, Tracheal Visfatin Level, and Lung Histological Changes in Ovalbumin-Sensitized Female Wistar Rats.
Topics: Animals; Diet, High-Fat; Female; Inflammation; Methacholine Chloride; Nicotinamide Phosphoribosyltransferase; Obesity; Ovalbumin; Rats; Rats, Wistar; Respiratory Hypersensitivity; Sensitivity and Specificity; Trachea | 2018 |
Repeated airway constrictions in mice do not alter respiratory function.
Topics: Airway Remodeling; Animals; Bronchoconstriction; Female; Inflammation; Methacholine Chloride; Mice, Inbred BALB C; Muscle, Smooth | 2018 |
Bacterial respiratory tract inflammation in neonatal rat model is attenuated by benzofuran through inhibition of GATA3.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Benzofurans; Bronchoconstrictor Agents; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; GATA3 Transcription Factor; Histocytochemistry; Inflammation; Lung; Methacholine Chloride; Rats; Serum; Treatment Outcome | 2018 |
Effect of CPAP on airway reactivity and airway inflammation in children with moderate-severe asthma.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Child; Continuous Positive Airway Pressure; Female; Forced Expiratory Volume; Humans; Inflammation; Male; Methacholine Chloride | 2019 |
Anti-thymic stromal lymphopoietin antibody suppresses airway remodeling in asthma through reduction of MMP and CTGF.
Topics: Airway Remodeling; Animals; Antibodies, Monoclonal; Asthma; Connective Tissue Growth Factor; Cytokines; Disease Models, Animal; Female; Immunoglobulin E; Inflammation; Lung; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Plethysmography; Thymic Stromal Lymphopoietin; Transforming Growth Factor beta | 2019 |
Hypoxia enhances CD8
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Bronchoconstrictor Agents; CD8-Positive T-Lymphocytes; Cells, Cultured; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Lung; Methacholine Chloride; Mice, Transgenic; Respiratory Hypersensitivity | 2019 |
Cystathionine γ-lyase deficiency enhances airway reactivity and viral-induced disease in mice exposed to side-stream tobacco smoke.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Bronchoalveolar Lavage Fluid; Cystathionine gamma-Lyase; Cytokines; Female; Genetic Predisposition to Disease; Hydrogen Sulfide; Inflammation; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Respiratory Hypersensitivity; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Tobacco Smoke Pollution | 2019 |
Neutrophilic inflammation in asthma and defective epithelial translational control.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Albuterol; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Cell Line, Tumor; Cytoplasm; Epithelial Cells; Epithelium; Female; Forced Expiratory Volume; Humans; Inflammation; Interleukin-17; Interleukin-8; Lung; Male; Methacholine Chloride; Middle Aged; Neutrophils; Randomized Controlled Trials as Topic; Respiratory Function Tests; Smoking; Tumor Necrosis Factor-alpha; Young Adult | 2019 |
Association between eosinophilic airway inflammation and persistent airflow limitation.
Topics: Asthma; Bronchial Provocation Tests; Case-Control Studies; Cell Count; Child; Eosinophil Cationic Protein; Eosinophils; Female; Humans; Inflammation; Male; Methacholine Chloride; Respiratory Function Tests; Sputum; Statistics, Nonparametric | 2013 |
Baseline airway inflammation may be a determinant of the response to ozone exposure in asthmatic patients.
Topics: Adult; Asthma; Atmosphere Exposure Chambers; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Inflammation; Inhalation Exposure; Male; Methacholine Chloride; Neutrophils; Oxidants, Photochemical; Ozone; Sputum | 2013 |
Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma.
Topics: Adolescent; Adult; Animals; Asthma; Disease Models, Animal; Eflornithine; Female; Humans; Hypersensitivity; Inflammation; Lung; Male; Methacholine Chloride; Mice; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Ovalbumin; Polyamines; Spermine; Sputum; Young Adult | 2013 |
Requirement of apoptosis-inducing kinase 1 for the induction of bronchial asthma following stimulation with ovalbumin.
Topics: Animals; Apoptosis; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Eosinophils; Goblet Cells; Immunoglobulin E; Inflammation; Interleukin-13; Interleukin-5; Lung; MAP Kinase Kinase Kinase 5; MAP Kinase Signaling System; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophil Infiltration; Ovalbumin; Tumor Necrosis Factor-alpha | 2013 |
Differential effects of allergen challenge on large and small airway reactivity in mice.
Topics: Airway Remodeling; Allergens; Animals; Antibody Specificity; Bronchial Hyperreactivity; Bronchial Provocation Tests; Calcium; Dinoprostone; Disease Models, Animal; Female; Immunoglobulin E; Inflammation; Methacholine Chloride; Mice; Ovalbumin | 2013 |
Fish oil has beneficial effects on allergen-induced airway inflammation and hyperreactivity in mice.
Topics: Allergens; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Cytokines; Fatty Acids, Unsaturated; Fish Oils; Immunoglobulin E; Immunoglobulin G; Inflammation; Leukocytes; Lung; Male; Methacholine Chloride; Mice; Ovalbumin; Pancreatic Elastase | 2013 |
The CC16 A38G polymorphism is associated with asymptomatic airway hyper-responsiveness and development of late-onset asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Case-Control Studies; Female; Genetic Association Studies; Genotype; Humans; Inflammation; Male; Methacholine Chloride; Polymorphism, Single Nucleotide; Respiratory Hypersensitivity; Respiratory System; Surveys and Questionnaires; Uteroglobin; Young Adult | 2013 |
IL-13 immunotoxin accelerates resolution of lung pathological changes triggered by silica particles in mice.
Topics: Administration, Intranasal; Animals; Cell Proliferation; Cells, Cultured; Exotoxins; Fibroblasts; Granuloma; Inflammation; Interleukin-13; Interleukin-4 Receptor alpha Subunit; Interleukin-8; Lung; Lymphotoxin-alpha; Male; Methacholine Chloride; Mice; Pseudomonas; Receptors, Interleukin-13; Recombinant Proteins; Respiratory Hypersensitivity; Silicon Dioxide; Silicosis; Tumor Necrosis Factor-alpha; Up-Regulation | 2013 |
Naringenin inhibits allergen‑induced airway remodeling in a murine model of asthma.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Differentiation; Chronic Disease; Cytokines; Disease Models, Animal; Female; Fibrosis; Flavanones; Immunoglobulin E; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Th2 Cells | 2014 |
The complex relationship between inflammation and lung function in severe asthma.
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Child; Cytokines; Female; Humans; Inflammation; Lung; Male; Methacholine Chloride; Mice; Mice, Transgenic; Middle Aged; Severity of Illness Index; Sputum | 2014 |
ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma.
Topics: Activating Transcription Factor 6; Airway Remodeling; Allergens; Animals; Antibody Specificity; Asthma; Bronchial Hyperreactivity; Chemokines, CC; Chemokines, CXC; Cytokines; Disease Models, Animal; eIF-2 Kinase; Eosinophils; Gene Expression; Gene Order; Gene Targeting; Humans; Immunoglobulin E; Inflammation; Lung; Membrane Proteins; Methacholine Chloride; Mice; Mice, Transgenic; Ovalbumin; Th2 Cells; Transgenes; Unfolded Protein Response | 2014 |
Comprehensive multiplexed protein quantitation delineates eosinophilic and neutrophilic experimental asthma.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Biomarkers; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Female; Hydrocortisone; Inflammation; Inflammation Mediators; Leukocyte Count; Lipopolysaccharides; Mass Spectrometry; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Phenotype; Protein Array Analysis; Proteome; Respiratory Mechanics | 2014 |
The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.
Topics: Allergens; Animals; Aspergillus oryzae; Asthma; Bronchial Hyperreactivity; Female; Immunohistochemistry; Inflammation; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Mucin 5AC; Mucus; Ovalbumin; Species Specificity | 2015 |
Hyaluronan mediates airway hyperresponsiveness in oxidative lung injury.
Topics: Alpha-Globulins; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Chlorine; Enzyme Activation; Extracellular Matrix; Hyaluronic Acid; Inflammation; Lung Injury; Membrane Potentials; Methacholine Chloride; Mice; Mice, Inbred C57BL; Muscle Contraction; Myocytes, Smooth Muscle; Oxidative Stress; Patch-Clamp Techniques; Reactive Oxygen Species; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Trachea | 2015 |
Exhaled Nitric Oxide and Airway Hyperresponsiveness to Adenosine 5'-monophosphate and Methacholine in Children with Asthma.
Topics: Adenosine Monophosphate; Adolescent; Asthma; Breath Tests; Bronchial Provocation Tests; Child; Eosinophil Cationic Protein; Eosinophils; Female; Humans; Immunoglobulin E; Inflammation; Linear Models; Male; Methacholine Chloride; Nitric Oxide | 2015 |
Vagotomy reverses established allergen-induced airway hyperreactivity to methacholine in the mouse.
Topics: Action Potentials; Allergens; Analysis of Variance; Animals; Bronchoalveolar Lavage; Bronchoconstrictor Agents; Female; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Respiratory Hypersensitivity; Vagotomy; Vagus Nerve | 2015 |
Increased airway reactivity and hyperinsulinemia in obese mice are linked by ERK signaling in brain stem cholinergic neurons.
Topics: Animals; Brain Stem; Bronchial Hyperreactivity; Bronchoconstriction; Cholinergic Neurons; Diet, High-Fat; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hyperinsulinism; Inflammation; Injections, Intraventricular; Insulin; MAP Kinase Signaling System; Methacholine Chloride; Mice, Inbred C57BL; Mice, Obese; Phosphatidylinositol 3-Kinases; Phosphorylation; Receptor, Insulin | 2015 |
Properdin Contributes to Allergic Airway Inflammation through Local C3a Generation.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Complement C3a; Eosinophils; Humans; Inflammation; Leukocyte Count; Lung; Methacholine Chloride; Mice; Mice, Inbred C57BL; Properdin; Th17 Cells; Th2 Cells | 2015 |
Allergen extract vs. component sensitization and airway inflammation, responsiveness and new-onset respiratory disease.
Topics: Adult; Allergens; Animals; Asthma; Biomarkers; Bronchial Provocation Tests; Cats; Exhalation; Female; Follow-Up Studies; Health Surveys; Humans; Immunization; Immunoglobulin E; Inflammation; Inhalation Exposure; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Respiratory Tract Diseases; Rhinitis; Sweden | 2016 |
Effects of antenatal lipopolysaccharide and postnatal hyperoxia on airway reactivity and remodeling in a neonatal mouse model.
Topics: Airway Remodeling; Animals; Animals, Newborn; Body Weight; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Elastin; Female; Hyperoxia; Inflammation; Lipopolysaccharides; Lung; Methacholine Chloride; Mice; Mice, Inbred C57BL; Oxygen; Pregnancy; Pregnancy, Animal; Respiration; Respiratory System | 2016 |
A novel peptide ADAM8 inhibitor attenuates bronchial hyperresponsiveness and Th2 cytokine mediated inflammation of murine asthmatic models.
Topics: ADAM Proteins; Animals; Antigens, CD; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Disease Models, Animal; Eosinophils; Gene Expression Regulation; Inflammation; Membrane Proteins; Methacholine Chloride; Mice, Inbred BALB C; Mice, Knockout; Peptides, Cyclic; Receptors, IgE; RNA, Messenger; Solubility; Th2 Cells | 2016 |
Comparison of diagnostic validity of mannitol and methacholine challenges and relationship to clinical status and airway inflammation in steroid-naïve asthmatic patients.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; Cross-Sectional Studies; Female; Humans; Inflammation; Inflammation Mediators; Male; Mannitol; Methacholine Chloride; Middle Aged; Nitric Oxide; Respiratory Function Tests; Sensitivity and Specificity; Severity of Illness Index; Skin Tests | 2017 |
Indoleamine 2,3-Dioxygenase Is Not a Pivotal Regulator Responsible for Suppressing Allergic Airway Inflammation through Adipose-Derived Stem Cells.
Topics: Adipose Tissue; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell- and Tissue-Based Therapy; Cells, Cultured; Eosinophils; Female; Goblet Cells; Hyperplasia; Immunoglobulin E; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-13; Interleukin-4; Interleukin-5; Lymphocyte Count; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; T-Lymphocytes, Regulatory; Transforming Growth Factor beta | 2016 |
Inflammation and airway hyperresponsiveness after chlorine exposure are prolonged by Nrf2 deficiency in mice.
Topics: Animals; Bronchoalveolar Lavage; Buthionine Sulfoximine; Chlorine; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Humans; Inflammation; Isothiocyanates; Lung; Methacholine Chloride; Mice; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Respiratory Hypersensitivity; RNA, Messenger; Sulfoxides | 2017 |
Bronchoconstriction Induces Structural and Functional Airway Alterations in Non-sensitized Rats.
Topics: Actins; Airway Remodeling; Allergens; Animals; Bronchoconstriction; Bronchoconstrictor Agents; Eosinophils; Inflammation; Lung; Male; Mechanical Phenomena; Methacholine Chloride; Ovalbumin; Rats; Rats, Sprague-Dawley; Respiratory Hypersensitivity | 2017 |
Airway responsiveness and inflammation in adolescent elite swimmers.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cross-Sectional Studies; Female; Humans; Inflammation; Lung; Male; Methacholine Chloride; Nitric Oxide; Respiratory Function Tests; Spirometry; Swimming | 2008 |
Correlation between airway inflammation and loss of deep-inhalation bronchoprotection in asthma.
Topics: Adult; Asthma; Breath Tests; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Eosinophils; Female; Humans; Inflammation; Male; Methacholine Chloride; Nitric Oxide; Sputum | 2008 |
Vitamin C and exercise-induced bronchoconstriction in athletes.
Topics: Adrenergic beta-Agonists; Asthma, Exercise-Induced; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents; Capillary Permeability; Eicosanoids; Epithelial Cells; Exercise; Humans; Inflammation; Mast Cells; Methacholine Chloride; Muscle, Smooth; Sports | 2009 |
Immunoglobulin E antibodies enhance pulmonary inflammation induced by inhalation of a chemical hapten.
Topics: Airway Resistance; Animals; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cell Count; Chemokine CCL2; Dinitrobenzenes; Disease Models, Animal; Eosinophils; Haptens; Immunization; Immunoglobulin E; Inflammation; Killer Cells, Natural; Lung; Metaplasia; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Natural Killer T-Cells; Occupational Diseases; T-Lymphocytes; Trinitrobenzenesulfonic Acid | 2009 |
Multiple challenges in a mouse model of chemical-induced asthma lead to tolerance: ventilatory and inflammatory responses are blunted, immunologic humoral responses are not.
Topics: Administration, Intranasal; Animals; Antibody Formation; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytokines; Immune Tolerance; Immunoglobulin E; Immunoglobulin G; Inflammation; Lung; Lymph Nodes; Lymphocytes; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Respiratory Mechanics | 2009 |
Altered regulation of aquaporin gene expression in allergen and IL-13-induced mouse models of asthma.
Topics: Animals; Aquaporin 1; Aquaporin 4; Aquaporin 5; Asthma; Bronchoconstrictor Agents; Disease Models, Animal; Female; Gene Expression Regulation; Inflammation; Interleukin-13; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Models, Biological | 2009 |
Dissociation of airway inflammation and hyperresponsiveness by cyclooxygenase inhibition in allergen challenged mice.
Topics: Allergens; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Female; Immunoglobulin E; Immunoglobulin G; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C | 2009 |
Relationship between amphiregulin and airway inflammation in children with asthma and eosinophilic bronchitis.
Topics: Amphiregulin; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Case-Control Studies; Child; EGF Family of Proteins; Enzyme-Linked Immunosorbent Assay; Eosinophils; Female; Glycoproteins; Humans; Immunoglobulin E; Inflammation; Intercellular Signaling Peptides and Proteins; Leukocyte Count; Male; Methacholine Chloride; Mucins; Prospective Studies; Sputum; Statistics, Nonparametric; Up-Regulation | 2009 |
Muscarinic M3 receptor stimulation increases cigarette smoke-induced IL-8 secretion by human airway smooth muscle cells.
Topics: Acetylcholine; Bronchi; Cells, Cultured; Chemokine CCL5; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Interleukin-6; Interleukin-8; Methacholine Chloride; Myocytes, Smooth Muscle; Neurotransmitter Agents; Pulmonary Disease, Chronic Obstructive; Receptor, Muscarinic M3; Smoking | 2009 |
Mouse models of asthma: a comparison between C57BL/6 and BALB/c strains regarding bronchial responsiveness, inflammation, and cytokine production.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Humans; Immunoglobulin E; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Ovalbumin | 2009 |
Acid aspiration-induced airways hyperresponsiveness in mice.
Topics: Administration, Inhalation; Aerosols; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Cell Count; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Rate; Hydrochloric Acid; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Respiratory Mechanics; Time Factors | 2009 |
Clinical and inflammatory features of occupational asthma caused by persulphate salts in comparison with asthma associated with occupational rhinitis.
Topics: Adult; Ammonium Sulfate; Asthma; Eosinophilia; Female; Humans; Inflammation; Male; Methacholine Chloride; Occupational Diseases; Retrospective Studies; Rhinitis; Young Adult | 2010 |
Sensitization to inhaled ryegrass pollen by collateral priming in a murine model of allergic respiratory disease.
Topics: Airway Resistance; Animals; Antigens, Plant; Blotting, Western; Bronchial Hyperreactivity; Bronchial Provocation Tests; Disease Models, Animal; Gene Expression; Immunization; Immunoglobulin E; Immunoglobulin G; Inflammation; Interleukin-13; Interleukin-4; Interleukin-5; Lolium; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Plant Extracts; Plant Proteins; Pollen; Respiratory Hypersensitivity; Th2 Cells | 2010 |
Prostaglandin modulation of airway inflammation and hyperresponsiveness in mice sensitized without adjuvant.
Topics: Adjuvants, Immunologic; Animals; Bronchoalveolar Lavage; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cysteine; Cytokines; Female; Hypersensitivity; Immunization; Inflammation; Leukotrienes; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Prostaglandins; Respiratory System | 2010 |
Airway hyperresponsiveness, peak flow variability and inflammatory markers in non-asthmatic subjects with respiratory infections.
Topics: Adenosine; Adult; Aged; Air; Asthma; Biomarkers; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cold Temperature; Common Cold; Eosinophil Cationic Protein; Humans; Inflammation; Methacholine Chloride; Middle Aged; Nitric Oxide; Peak Expiratory Flow Rate; Respiratory Sounds; Young Adult | 2007 |
Increased expression of angiopoietins and Tie2 in the lungs of chronic asthmatic mice.
Topics: Angiopoietin-1; Angiopoietin-2; Animals; Asthma; Gene Expression Regulation; Hypersensitivity; Inflammation; Macrophages; Methacholine Chloride; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Models, Biological; Ovalbumin; Receptor Protein-Tyrosine Kinases; Receptor, TIE-2; Vascular Endothelial Growth Factor A | 2011 |
Increase in exhaled nitric oxide is associated with bronchial hyperresponsiveness among apprentices.
Topics: Adolescent; Asthma; Beauty Culture; Biomarkers; Breath Tests; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Exhalation; Female; Follow-Up Studies; Food-Processing Industry; Humans; Incidence; Inflammation; Inhalation Exposure; Male; Methacholine Chloride; Nitric Oxide; Occupational Diseases; Occupational Exposure; Surveys and Questionnaires | 2010 |
Thalidomide attenuates airway hyperresponsiveness and eosinophilic inflammation in a murine model of allergic asthma.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Female; Goblet Cells; Hyperplasia; Inflammation; Interleukin-5; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Thalidomide; Tumor Necrosis Factor-alpha | 2010 |
MARCKS-related peptide modulates in vivo the secretion of airway Muc5ac.
Topics: Aerosols; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Goblet Cells; Inflammation; Inflammation Mediators; Intracellular Signaling Peptides and Proteins; Leukocyte Elastase; Lung; Male; Membrane Proteins; Metaplasia; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucin 5AC; Myristoylated Alanine-Rich C Kinase Substrate; Peptide Fragments; Respiratory Hypersensitivity; Respiratory System; Serotonin | 2010 |
Fractionation of swine barn dust and assessment of its impact on the respiratory tract following repeated airway exposure.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chemokines; Cytokines; Disease Models, Animal; Dust; Enzyme-Linked Immunosorbent Assay; Housing, Animal; Inflammation; Inhalation Exposure; Interleukin-1beta; Interleukin-6; Methacholine Chloride; Mice; Plethysmography; Respiratory System; Risk Assessment; Swine; Time Factors; Tumor Necrosis Factor-alpha | 2010 |
Proteome analysis of multiple compartments in a mouse model of chemical-induced asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation; Mass Spectrometry; Methacholine Chloride; Mice; Neutrophils; Oxidative Stress; Proteome; Toluene 2,4-Diisocyanate | 2010 |
M(3) muscarinic receptor antagonist bencycloquidium bromide attenuates allergic airway inflammation, hyperresponsiveness and remodeling in mice.
Topics: Airway Remodeling; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bronchoalveolar Lavage Fluid; Chemokines; Eosinophilia; Female; Gene Expression Regulation; Hypersensitivity; Inflammation; Lung; Matrix Metalloproteinases; Methacholine Chloride; Mice; Pneumonia; Receptor, Muscarinic M3; Respiratory System; RNA, Messenger | 2011 |
Hesperidin suppresses ovalbumin-induced airway inflammation in a mouse allergic asthma model.
Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Hesperidin; Immunoglobulin E; Inflammation; Interleukin-13; Interleukin-4; Interleukin-5; Leukocytes; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Respiratory System; Th2 Cells | 2012 |
Inhibition of airway inflammation, hyperresponsiveness and remodeling by soy isoflavone in a murine model of allergic asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Collagen; Eosinophils; Female; Glycine max; Hypersensitivity; Inflammation; Interferon-gamma; Interleukin-4; Interleukin-5; Isoflavones; Lung; Matrix Metalloproteinase 9; Methacholine Chloride; Mice; Mice, Inbred ICR; Mucus; Ovalbumin; Peroxidase; Respiratory System; Superoxide Dismutase; Tissue Inhibitor of Metalloproteinase-1 | 2011 |
Sputum inflammatory cells and allergen-induced airway responses in allergic asthmatic subjects.
Topics: Allergens; Asthma; Bronchoconstrictor Agents; Eosinophils; Humans; Inflammation; Methacholine Chloride; Sputum | 2011 |
Comparison of bronchial hyperresponsiveness to methacholine and adenosine and airway inflammation markers in patients with suspected asthma.
Topics: Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Biomarkers; Breath Tests; Bronchi; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Eosinophils; Exhalation; Female; Humans; Inflammation; Leukocyte Count; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Sensitivity and Specificity; Sputum; Young Adult | 2011 |
Relationship between bronchial hyperreactivity and bronchodilation in patients with allergic rhinitis.
Topics: Adult; Albuterol; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchodilator Agents; Cross-Sectional Studies; Female; Forced Expiratory Flow Rates; Forced Expiratory Volume; Humans; Inflammation; Male; Methacholine Chloride; Middle Aged; Rhinitis, Allergic, Perennial; Risk Factors; Spirometry; Vital Capacity; Young Adult | 2011 |
A single DH gene segment is sufficient for the establishment of an asthma phenotype in a murine model of allergic airway inflammation.
Topics: Allergens; Animals; Asthma; B-Lymphocytes; Bronchial Hyperreactivity; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hypersensitivity; Immunoglobulin E; Immunoglobulin G; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Ovalbumin | 2011 |
Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage; Chemokines; Disease Models, Animal; Gene Expression Regulation; Inflammation; Interferon-gamma; Lung; Mast Cells; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Oligonucleotide Array Sequence Analysis; Th1 Cells; Th2 Cells | 2011 |
Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation.
Topics: Adult; Asthma; Bariatric Surgery; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes; Cross-Sectional Studies; Female; Humans; Inflammation; Male; Methacholine Chloride; Middle Aged; Obesity; Prospective Studies; Respiratory Function Tests; Treatment Outcome; Weight Loss | 2011 |
S-nitrosoglutathione supplementation to ovalbumin-sensitized and -challenged mice ameliorates methacholine-induced bronchoconstriction.
Topics: Administration, Inhalation; Aerosols; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mucin 5AC; Ovalbumin; S-Nitrosoglutathione; Tracheotomy | 2011 |
Capsicum annuum L. methanolic extract inhibits ovalbumin-induced airway inflammation and oxidative stress in a mouse model of asthma.
Topics: Administration, Oral; Animals; Antioxidants; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Capsicum; Cytokines; Disease Models, Animal; Female; Fruit; Immunoglobulin E; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; T-Lymphocytes, Helper-Inducer | 2011 |
Lactobacillus gasseri suppresses Th17 pro-inflammatory response and attenuates allergen-induced airway inflammation in a mouse model of allergic asthma.
Topics: Animals; Antibodies; Antigens, Dermatophagoides; Asthma; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Immunoglobulin E; Immunoglobulin G; Inflammation; Lactobacillus; Methacholine Chloride; Mice; Mice, Inbred BALB C; Probiotics; Th17 Cells | 2012 |
Inhibition of Pim1 kinase activation attenuates allergen-induced airway hyperresponsiveness and inflammation.
Topics: Allergens; Animals; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Female; Goblet Cells; Hypersensitivity; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Pneumonia; Proto-Oncogene Proteins c-pim-1; Respiratory Hypersensitivity | 2012 |
Alcohol reduces airway hyperresponsiveness (AHR) and allergic airway inflammation in mice.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Calcitonin Gene-Related Peptide; Cell Count; Cell Line; Cytokines; Eosinophils; Ethanol; Goblet Cells; Immunoglobulin E; Inflammation; Lung; Male; Metaplasia; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; PPAR gamma; Th2 Cells | 2012 |
Neonatal epithelial hypoxia inducible factor-1α expression regulates the response of the lung to experimental asthma.
Topics: Airway Resistance; Animals; Animals, Newborn; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cell Count; Cytokines; Eosinophil Major Basic Protein; Eosinophils; Female; Gene Expression; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Immunity, Innate; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Transgenic; Ovalbumin; Random Allocation | 2012 |
IL-33 induces Th17-mediated airway inflammation via mast cells in ovalbumin-challenged mice.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cell Count; Cell Differentiation; Cytokines; Eosinophils; Female; Gene Expression; Inflammation; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Interleukins; Lung; Mast Cells; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Ovalbumin; Receptors, Interleukin; Th17 Cells; Th2 Cells | 2012 |
Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB.
Topics: Airway Resistance; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Adhesion Molecules; Cell Count; Chemokines; Chitinases; Cytokines; Disease Models, Animal; DNA-Binding Proteins; Dose-Response Relationship, Drug; Female; Flavonoids; Flavonols; Genes, Reporter; Inflammation; Inflammation Mediators; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucin 5AC; Mucus; NF-kappa B; Nitric Oxide Synthase Type II; Ovalbumin; Protein Transport; Tumor Necrosis Factor-alpha | 2012 |
Hypoxia response in asthma: differential modulation on inflammation and epithelial injury.
Topics: Airway Remodeling; Animals; Apoptosis; Asthma; Cell Hypoxia; CX3C Chemokine Receptor 1; Hydroxybenzoates; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Procollagen-Proline Dioxygenase; Receptors, Chemokine; Respiratory Mucosa; RNA Interference; RNA, Small Interfering; Signal Transduction | 2012 |
Intranasal administration of poly(I:C) and LPS in BALB/c mice induces airway hyperresponsiveness and inflammation via different pathways.
Topics: Administration, Intranasal; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Bronchoconstrictor Agents; Cytokines; Female; Inflammation; Interferon Inducers; Lipopolysaccharides; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Myeloid Differentiation Factor 88; Poly I-C; Respiratory Mechanics; Signal Transduction | 2012 |
Chronic allergic inflammation causes vascular remodeling and pulmonary hypertension in BMPR2 hypomorph and wild-type mice.
Topics: Analysis of Variance; Animals; Arterioles; Blood Pressure; Blotting, Western; Bone Morphogenetic Protein Receptors, Type II; Bronchoalveolar Lavage; DNA Primers; Enzyme-Linked Immunosorbent Assay; Genotype; Hypersensitivity; Hypertension, Pulmonary; Immunohistochemistry; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mutation; Polymerase Chain Reaction; Pyroglyphidae; Signal Transduction | 2012 |
The tyrosine kinase inhibitor masitinib blunts airway inflammation and improves associated lung mechanics in a feline model of chronic allergic asthma.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Asthma; Benzamides; Bronchoalveolar Lavage Fluid; Cats; Chronic Disease; Cynodon; Eosinophils; Immunoglobulin E; Inflammation; Lung; Male; Methacholine Chloride; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Thiazoles | 2012 |
Corticosteroid treatment inhibits airway hyperresponsiveness and lung injury in a murine model of chemical-induced airway inflammation.
Topics: Animals; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Collagen; Dexamethasone; Disease Models, Animal; Female; Glucocorticoids; Inflammation; Lung; Lung Injury; Macrophages; Melphalan; Methacholine Chloride; Mice; Mice, Inbred C57BL; Neutrophils; Time Factors | 2012 |
Bronchial inflammation and hyperresponsiveness in well controlled asthma.
Topics: Adolescent; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cross-Sectional Studies; Eosinophils; Female; Humans; Hypersensitivity, Immediate; Inflammation; Male; Methacholine Chloride; Middle Aged; Neutrophils; Spirometry; Sputum; Young Adult | 2012 |
A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthma.
Topics: Amino Alcohols; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chemokine CCL2; Female; Goblet Cells; Humans; Hyperplasia; Immunoglobulin E; Inflammation; Interferon-gamma; Interleukins; Lung; Lysophospholipids; Mast Cells; Methacholine Chloride; Mice; Mice, Inbred C57BL; NF-kappa B; Ovalbumin; Phosphotransferases (Alcohol Group Acceptor); Sphingosine; Tumor Necrosis Factor-alpha | 2013 |
Spleen tyrosine kinase inhibition attenuates airway hyperresponsiveness and pollution-induced enhanced airway response in a chronic mouse model of asthma.
Topics: Air Pollutants; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, Animal; Female; Humans; Inflammation; Intracellular Signaling Peptides and Proteins; Keratinocytes; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Respiratory Mucosa; Syk Kinase; Vascular Endothelial Growth Factor A | 2013 |
Effect of the fungal immunomodulatory protein FIP-fve on airway inflammation and cytokine production in mouse asthma model.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Fungal Proteins; Inflammation; Inflammation Mediators; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Respiratory System; Th1 Cells; Th2 Cells | 2013 |
The neonatal susceptibility window for inhalant allergen sensitization in the atopically predisposed canine asthma model.
Topics: Administration, Inhalation; Allergens; Ambrosia; Animals; Animals, Newborn; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Desensitization, Immunologic; Dogs; Eosinophilia; Female; Glucosamine; Immune Tolerance; Immunoglobulin E; Immunologic Factors; Inflammation; Methacholine Chloride; Organophosphorus Compounds; Time Factors; Toll-Like Receptor 4 | 2013 |
Dok adaptors play anti-inflammatory roles in pulmonary homeostasis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytokines; DNA-Binding Proteins; Fibrosis; Homeostasis; Hyperplasia; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphoproteins; Pneumonia; Respiratory Mucosa; RNA-Binding Proteins; Th2 Cells | 2013 |
Neutralization of TSLP inhibits airway remodeling in a murine model of allergic asthma induced by chronic exposure to house dust mite.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dendritic Cells; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; GATA3 Transcription Factor; Homeostasis; Hypersensitivity; Inflammation; Interleukin-13; Interleukin-4; Methacholine Chloride; Mice; Mice, Inbred BALB C; Pyroglyphidae; Th2 Cells; Thymic Stromal Lymphopoietin | 2013 |
Influence of lipopolysaccharide exposure on airway function and allergic responses in developing mice.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cell Count; Cytokines; Dose-Response Relationship, Drug; Endotoxins; Inflammation; Lipopolysaccharides; Lymphocytes; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Reference Values | 2002 |
CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Cell Line; Cytokines; Dose-Response Relationship, Drug; Genetic Therapy; Inflammation; Interleukin-10; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, SCID; Ovalbumin; Protein Engineering; Pulmonary Eosinophilia; T-Lymphocytes, Helper-Inducer; Th2 Cells; Transduction, Genetic | 2002 |
Long-lived Th2 memory in experimental allergic asthma.
Topics: Acute Disease; Aerosols; Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Female; Immunoglobulins; Immunologic Memory; Inflammation; Lung; Lymph Nodes; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Spleen; Th2 Cells; Time Factors | 2002 |
Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation.
Topics: Actins; Airway Resistance; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Bronchoconstriction; Eosinophils; Extracellular Matrix; Female; Inflammation; Interleukin-13; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucins; Muscle, Smooth; Ovalbumin | 2002 |
src homology 2 domain-containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation.
Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes; Cell Differentiation; Cross-Linking Reagents; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Enzyme-Linked Immunosorbent Assay; Eosinophils; Flow Cytometry; Heterozygote; Hypersensitivity; Immunoblotting; Inflammation; Interleukin-13; Interleukin-6; Intracellular Signaling Peptides and Proteins; Mast Cells; Methacholine Chloride; Mice; Mice, Inbred C3H; Microscopy, Fluorescence; Mutation; Phenotype; Precipitin Tests; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Interleukin-4; Signal Transduction; src Homology Domains; T-Lymphocytes; Th1 Cells; Th2 Cells; Time Factors | 2003 |
Inflammatory effects of inhaled endotoxin-contaminated metal working fluid aerosols in rats.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Endotoxins; Flow Cytometry; Industrial Oils; Inflammation; Male; Metallurgy; Methacholine Chloride; Rats; Rats, Wistar; Respiration Disorders; Respiratory Function Tests; Respiratory System; Statistics, Nonparametric | 2003 |
A broad-spectrum caspase inhibitor attenuates allergic airway inflammation in murine asthma model.
Topics: Aerosols; Allergens; Amino Acid Chloromethyl Ketones; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Caspase Inhibitors; Cell Movement; Cysteine Proteinase Inhibitors; Disease Models, Animal; Inflammation; Interleukin-4; Interleukin-5; Intubation, Intratracheal; Leukocytes; Lung; Lymphocyte Activation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; T-Lymphocytes | 2003 |
The effects of IL-5 on airway physiology and inflammation in rats.
Topics: Animals; Blood Cells; Bronchoalveolar Lavage Fluid; Cell Differentiation; Cytokines; Dose-Response Relationship, Drug; Eosinophils; Humans; Immunization; Immunoglobulin E; Inflammation; Interleukin-5; Intubation, Intratracheal; Lung; Lymphocyte Subsets; Male; Methacholine Chloride; Ovalbumin; Rats; Rats, Inbred BN; Recombinant Proteins; Respiratory System; Respiratory Tract Diseases; RNA, Messenger; Stem Cells | 2003 |
Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma.
Topics: Allergens; Androstadienes; Animals; Asthma; Blood Proteins; Blotting, Western; Bronchoalveolar Lavage Fluid; Cations; Cells, Cultured; Chromones; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophil Granule Proteins; Female; Genetic Vectors; Immunohistochemistry; Inflammation; Interleukin-4; Interleukin-5; Lac Operon; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Morpholines; Phenotype; Phosphatidylinositol 3-Kinases; Phosphoric Monoester Hydrolases; Phosphorylation; PTEN Phosphohydrolase; Ribonucleases; Time Factors; Tumor Suppressor Proteins; Wortmannin | 2003 |
Relationship of airway wall thickness to airway sensitivity and airway reactivity in asthma.
Topics: Adrenergic beta-Agonists; Aged; Airway Resistance; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Eosinophils; Female; Forced Expiratory Volume; Humans; Hyperplasia; Hypertrophy; Inflammation; Leukocyte Count; Male; Methacholine Chloride; Middle Aged; Severity of Illness Index; Sputum; Tomography, X-Ray Computed | 2003 |
Beta-arrestin-2 regulates the development of allergic asthma.
Topics: Animals; Arrestins; Asthma; beta-Arrestin 2; beta-Arrestins; Bronchoconstrictor Agents; CD3 Complex; CD4 Antigens; CD4-Positive T-Lymphocytes; Cell Membrane; Chemotaxis; Cytokines; Endotoxins; Female; Genotype; Immunoglobulin E; Immunoglobulin G; Inflammation; Lipopolysaccharides; Lung; Lymphocytes; Macrophages; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Transgenic; Protein Structure, Tertiary; T-Lymphocytes; Th2 Cells; Time Factors | 2003 |
Accumulation of peribronchial mast cells in a mouse model of ovalbumin allergen induced chronic airway inflammation: modulation by immunostimulatory DNA sequences.
Topics: Adjuvants, Immunologic; Administration, Intranasal; Allergens; Animals; Bone Marrow Cells; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cell Aggregation; Cell Count; Cell Division; Chronic Disease; CpG Islands; Disease Models, Animal; DNA; DNA-Binding Proteins; Drug Administration Schedule; Female; Fluorescent Dyes; Growth Inhibitors; Immunoglobulin E; Inflammation; Injections, Subcutaneous; Interleukin-4; Interleukin-9; Lung; Mast Cells; Methacholine Chloride; Mice; Mice, Inbred BALB C; Oligodeoxyribonucleotides; Ovalbumin; Receptors, Cell Surface; Rhodamines; Toll-Like Receptor 9 | 2003 |
Airway inflammation after cessation of exposure to agents causing occupational asthma.
Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Cohort Studies; Female; Follow-Up Studies; Humans; Inflammation; Inflammation Mediators; Interleukin-8; Logistic Models; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Occupational Exposure; Peroxidase; Probability; Respiratory Function Tests; Risk Assessment; Sampling Studies; Sputum; Time Factors | 2004 |
Opposing effects of short- and long-term stress on airway inflammation.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cytokines; Inflammation; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mifepristone; Receptors, Steroid; Stress, Physiological | 2004 |
Nasal inflammation and bronchial reactivity to methacholine in atopic children with respiratory symptoms.
Topics: Adolescent; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Preschool; Conjunctivitis, Allergic; Eosinophils; Female; Humans; Immunoglobulin E; Inflammation; Intercellular Adhesion Molecule-1; Male; Methacholine Chloride; Nasal Mucosa; Pyroglyphidae; Respiratory Mechanics; Rhinitis, Allergic, Perennial; Skin Tests | 2003 |
Immunostimulatory DNA inhibits transforming growth factor-beta expression and airway remodeling.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; DNA; Female; Humans; Inflammation; Interferon-gamma; Interleukin-5; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscle, Smooth; Ovalbumin; Respiratory System; Th2 Cells; Transforming Growth Factor beta | 2004 |
Recall helper T cell response: T helper 1 cell-resistant allergic susceptibility without biasing uncommitted CD4 T cells.
Topics: Animals; Antigens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; CD4 Antigens; CD4-Positive T-Lymphocytes; Disease Models, Animal; Eosinophils; Female; Flow Cytometry; Genetic Predisposition to Disease; Hypersensitivity, Immediate; Immune Tolerance; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Receptors, Interleukin-2; Th1 Cells; Th2 Cells | 2004 |
Site of inflammation influences site of hyperresponsiveness in experimental asthma.
Topics: Aerosols; Animals; Asthma; Bronchi; Bronchoconstrictor Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Respiratory Function Tests; Respiratory Hypersensitivity; Time Factors; Vascular Resistance | 2003 |
Bronchial hyperresponsiveness to methacholine is associated with increased common carotid intima-media thickness in men.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; C-Reactive Protein; Carotid Artery, Common; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Inflammation; Male; Methacholine Chloride; Middle Aged; Sex Factors; Single-Blind Method; Smoking; Tunica Intima | 2004 |
alpha-Lipoic acid inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; DNA; Immunoglobulin E; Inflammation; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; NF-kappa B; Oxidative Stress; Thioctic Acid | 2004 |
Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling.
Topics: Animals; Antibodies, Monoclonal; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Inflammation; Interleukin-13; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Respiratory System | 2004 |
Omalizumab and changes in airway hyperresponsiveness.
Topics: Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Humans; Immunoglobulin E; Inflammation; Methacholine Chloride; Omalizumab | 2005 |
Involvement of mast cells in adenosine-mediated bronchoconstriction and inflammation in an allergic mouse model.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Ambrosia; Animals; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cell Count; Cell Degranulation; Dose-Response Relationship, Drug; Inflammation; Leukocyte Count; Mast Cells; Methacholine Chloride; Mice; Muscarinic Agonists; p-Methoxy-N-methylphenethylamine; Respiratory Hypersensitivity | 2005 |
Nasal eosinophils display the best correlation with symptoms, pulmonary function and inflammation in allergic rhinitis.
Topics: Adolescent; Adult; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Cell Count; Cytokines; Eosinophils; Humans; Inflammation; Male; Methacholine Chloride; Nasal Lavage Fluid; Neutrophils; Nose; Pollen; Rhinitis, Allergic, Seasonal; Rhinomanometry; Skin Tests; Spirometry | 2005 |
Augmentation of allergic inflammation in the airways of cyclooxygenase-2-deficient mice.
Topics: Animals; Arachidonic Acid; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cysteine; Dinoprostone; Female; Immunoglobulin E; Inflammation; Interleukin-13; Leukotrienes; Lung; Male; Metaplasia; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Sulfonamides | 2005 |
TNF-alpha induces the late-phase airway hyperresponsiveness and airway inflammation through cytosolic phospholipase A(2) activation.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytosol; Disease Models, Animal; Enzyme Activation; Histamine; Inflammation; Leukotriene B4; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Phospholipases A; Platelet Activating Factor; Pulmonary Eosinophilia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Syk activation in dendritic cells is essential for airway hyperresponsiveness and inflammation.
Topics: Allergens; Animals; B-Lymphocytes; Bone Marrow Cells; Bronchial Hyperreactivity; Cells, Cultured; Coculture Techniques; Cytokines; Dendritic Cells; Enzyme Activation; Female; Goblet Cells; Inflammation; Interleukin-13; Intracellular Signaling Peptides and Proteins; Mast Cells; Metaplasia; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Oxazines; Protein-Tyrosine Kinases; Pyridines; Respiratory System; Syk Kinase | 2006 |
Respiratory syncytial virus infection in a murine model of cystic fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Inflammation; Lung; Lymphocytes; Methacholine Chloride; Mice; Mice, Inbred CFTR; Neutrophils; Nitrates; Nitric Oxide; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses | 2006 |
Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation.
Topics: Animals; Bronchoalveolar Lavage Fluid; Complement Activation; Complement C4; Complement Pathway, Alternative; Complement System Proteins; Immunity, Innate; Inflammation; Methacholine Chloride; Mice; Mice, Inbred C57BL; Respiratory Hypersensitivity | 2006 |
Airway hyperreactivity in exacerbation of chronic asthma is independent of eosinophilic inflammation.
Topics: Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Chronic Disease; Cytokines; Eosinophils; Female; GATA1 Transcription Factor; Humans; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Ovalbumin | 2006 |
Cyclooxygenase-1 overexpression decreases Basal airway responsiveness but not allergic inflammation.
Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Humans; Hypersensitivity; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Transgenic; Ovalbumin; Plethysmography, Whole Body; Respiratory Function Tests; Reverse Transcriptase Polymerase Chain Reaction; Transgenes | 2006 |
Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice.
Topics: Acetylcholine; Allergens; Animals; Bronchial Hyperreactivity; Cytokines; Electrophysiology; Estrogen Receptor alpha; Estrogens; Female; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Knockout; Ovalbumin; Peripheral Nerves; Plethysmography; Receptor, Muscarinic M2; Respiratory Hypersensitivity; Serotonin; Trachea | 2007 |
The chemokine receptor D6 has opposing effects on allergic inflammation and airway reactivity.
Topics: Allergens; Animals; Bronchial Hyperreactivity; Chemokine Receptor D6; Chemokines, CC; Eosinophils; Inflammation; Leukocytes; Lung; Lung Diseases, Obstructive; Lymph Nodes; Methacholine Chloride; Mice; Mice, Knockout; Ovalbumin; Receptors, CCR10; Receptors, Chemokine; Respiratory Hypersensitivity; Transforming Growth Factor beta1 | 2007 |
[Alteration of bronchomotor tone after deep inhalation. Mechanisms and pediatric data].
Topics: Asthma; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Child; Exercise; Humans; Inflammation; Methacholine Chloride; Respiratory Function Tests; Respiratory Therapy | 2007 |
Catalase overexpression fails to attenuate allergic airways disease in the mouse.
Topics: Animals; Asthma; Bronchoconstrictor Agents; Catalase; Gene Expression Regulation; Hydrogen Peroxide; Inflammation; Inflammation Mediators; Lung; Methacholine Chloride; Mice; Mice, Transgenic; Ovalbumin; Oxidative Stress; Species Specificity | 2007 |
Inhibition of airway allergic disease by co-administration of flagellin with allergen.
Topics: Allergens; Animals; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Eosinophils; Female; Flagellin; Immunoglobulin G; Inflammation; Lymphocytes; Macrophages, Alveolar; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Pulmonary Ventilation; Recombinant Proteins; Respiratory Hypersensitivity; Spleen; T-Lymphocytes; Toll-Like Receptor 5 | 2008 |
Role of CD38 in TNF-alpha-induced airway hyperresponsiveness.
Topics: Administration, Intranasal; ADP-ribosyl Cyclase 1; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chemokines; In Vitro Techniques; Inflammation; Isometric Contraction; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Alveoli; Recombinant Proteins; Trachea; Tumor Necrosis Factor-alpha | 2008 |
Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage-derived cytokines.
Topics: Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Computational Biology; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inflammation; Male; Methacholine Chloride; Phenotype; Severity of Illness Index | 2008 |
Computational assessment of airway wall stiffness in vivo in allergically inflamed mouse models of asthma.
Topics: Airway Resistance; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Computer Simulation; Disease Models, Animal; Elasticity; Female; Inflammation; Injections, Intravenous; Methacholine Chloride; Mice; Mice, Inbred BALB C; Models, Biological; Ovalbumin; Time Factors | 2008 |
Sensitizing effects of chronic exposure and acute inhalation of ovalbumin aerosol on pulmonary C fibers in rats.
Topics: Administration, Inhalation; Aerosols; Allergens; Animals; Blood Pressure; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Heart Rate; Hypersensitivity; Inflammation; Lung; Male; Methacholine Chloride; Nerve Fibers, Unmyelinated; Neurons, Afferent; Ovalbumin; Rats; Rats, Inbred BN | 2008 |
Mepacrine alleviates airway hyperresponsiveness and airway inflammation in a mouse model of asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cysteine; Cytokines; Disease Models, Animal; Eosinophils; Immunoglobulin E; Inflammation; Leukotrienes; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Phospholipases A2, Secretory; Quinacrine | 2008 |
Attenuated methacholine airway response following repeat testing in a murine model of allergic airways disease.
Topics: Animals; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Female; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin | 2008 |
Increased maximal airway response to methacholine during seasonal allergic rhinitis in nonasthmatic subjects: relationships with airway wall thickness and inflammation.
Topics: Adult; Allergens; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Bronchoscopy; Dose-Response Relationship, Drug; Female; Humans; Inflammation; Male; Methacholine Chloride; Nebulizers and Vaporizers; Peak Expiratory Flow Rate; Pulmonary Ventilation; Rhinitis, Allergic, Perennial; Spirometry | 1995 |
Importance of impairment of the airway epithelium for ozone-induced airway hyperresponsiveness in guinea pigs.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Dose-Response Relationship, Drug; Eosinophils; Epithelium; Guinea Pigs; Inflammation; Injections, Intravenous; Lung; Macrophages; Male; Methacholine Chloride; Neutrophils; Ozone; T-Lymphocytes; Trachea | 1995 |
Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity.
Topics: Airway Resistance; Animals; Bronchial Hyperreactivity; Inflammation; Interleukin-6; Lung; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic | 1994 |
Involvement of thromboxane A2 in propranolol-induced bronchoconstriction after allergic bronchoconstriction in guinea pigs.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Asthma; Bridged Bicyclo Compounds; Bronchial Provocation Tests; Constriction, Pathologic; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Guinea Pigs; Hypersensitivity; Inflammation; Injections, Intravenous; Male; Methacholine Chloride; Premedication; Propranolol; Receptors, Prostaglandin; Thromboxane A2; Time Factors | 1994 |
Respiratory responses to repeated prolonged exposure to 0.12 ppm ozone.
Topics: Analysis of Variance; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cough; Environmental Exposure; Exercise Test; Forced Expiratory Volume; Humans; Inflammation; Male; Methacholine Chloride; Ozone; Pain; Plethysmography, Whole Body; Time Factors; Vital Capacity | 1994 |
Bronchial responsiveness to distilled water and methacholine and its relationship to inflammation and remodeling of the airways in asthma.
Topics: Adolescent; Adult; Asthma; Basement Membrane; Biopsy; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Bronchoconstrictor Agents; Eosinophils; Epithelium; Female; Forced Expiratory Volume; Humans; Inflammation; Leukocyte Count; Male; Methacholine Chloride; Middle Aged; Nebulizers and Vaporizers; Peak Expiratory Flow Rate; Water | 1996 |
The importance of leukotrienes in airway inflammation in a mouse model of asthma.
Topics: 5-Lipoxygenase-Activating Proteins; Allergens; Animals; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Carrier Proteins; Disease Models, Animal; Female; Immunoglobulin E; Inflammation; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Membrane Proteins; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Pulmonary Eosinophilia; Respiratory Function Tests; Respiratory System | 1996 |
Parainfluenza virus-induced persistence of airway inflammation, fibrosis, and dysfunction associated with TGF-beta 1 expression in brown Norway rats.
Topics: Airway Resistance; Animals; Animals, Newborn; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Disease Susceptibility; Fibrosis; Immunohistochemistry; In Situ Hybridization; Inflammation; Lung; Lung Compliance; Macrophages; Mast Cells; Methacholine Chloride; Parainfluenza Virus 1, Human; Rats; Rats, Inbred BN; Rats, Inbred F344; Respiratory Mechanics; Respiratory Tract Infections; Respirovirus Infections; Transforming Growth Factor beta | 1996 |
Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model.
Topics: Airway Resistance; Animals; Bronchoalveolar Lavage; Bronchoconstrictor Agents; CD28 Antigens; Cell Division; Disease Models, Animal; Flow Cytometry; Histocytochemistry; Hypersensitivity; Immunoglobulin E; Immunoglobulin G; Immunohistochemistry; Inflammation; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; T-Lymphocytes | 1996 |
Asthma, bronchial hyperreactivity and mediator release in children with birch pollinosis. ECP and EPX levels are not related to bronchial hyperreactivity.
Topics: Adolescent; Asthma; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Chymases; Conjunctiva; Eosinophil Granule Proteins; Eosinophil-Derived Neurotoxin; Female; Humans; Inflammation; Male; Methacholine Chloride; Peak Expiratory Flow Rate; Peroxidase; Pollen; Ribonucleases; Seasons; Serine Endopeptidases; Skin Tests; Trees; Tryptases | 1997 |
Respiratory syncytial virus infection results in airway hyperresponsiveness and enhanced airway sensitization to allergen.
Topics: Allergens; Animals; Bronchoconstrictor Agents; Cytokines; Eosinophils; Female; Humans; Hypersensitivity; Inflammation; Interferon-gamma; Interleukin-4; Interleukin-5; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Th2 Cells; Time Factors; Tumor Cells, Cultured | 1997 |
Bronchial hyperresponsiveness in lung transplant recipients: lack of correlation with airway inflammation.
Topics: Adult; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Cell Count; Eosinophils; Female; Humans; Inflammation; Lung; Lung Transplantation; Lymphocytes; Male; Mast Cells; Methacholine Chloride; Middle Aged; Saline Solution, Hypertonic | 1997 |
Intercellular adhesion molecule-1-deficient mice have antibody responses but impaired leukocyte recruitment.
Topics: Animals; Antibody Formation; Antigens, Differentiation; Bronchoalveolar Lavage Fluid; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Immunoglobulin E; Immunoglobulin G; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Lung; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Ovalbumin; Spleen; T-Lymphocytes | 1997 |
Induced sputum to assess airway inflammation: a study of reproducibility.
Topics: Adult; Allergens; Asthma; Blood Proteins; Bronchi; Bronchial Provocation Tests; Eosinophil Granule Proteins; Eosinophils; Epithelial Cells; Female; Forced Expiratory Volume; Humans; Inflammation; Leukocyte Count; Lymphocyte Count; Macrophages; Male; Methacholine Chloride; Middle Aged; Neutrophils; Reproducibility of Results; Rhinitis, Allergic, Seasonal; Ribonucleases; Skin Tests; Sputum; Vital Capacity | 1997 |
Effects of ozone on normal and potentially sensitive human subjects. Part I: Airway inflammation and responsiveness to ozone in normal and asthmatic subjects.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Biopsy; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoscopy; Data Interpretation, Statistical; Female; Forced Expiratory Volume; Humans; Immunohistochemistry; Inflammation; Interleukin-8; Lung; Male; Methacholine Chloride; Middle Aged; Ozone; Physical Exertion; Therapeutic Irrigation; Time Factors; Vital Capacity | 1997 |
Chronic cough resembles asthma with IL-5 and granulocyte-macrophage colony-stimulating factor gene expression in bronchoalveolar cells.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Chronic Disease; Cough; DNA Primers; DNA, Complementary; Female; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation; Interleukin-5; Male; Methacholine Chloride; Middle Aged; Polymerase Chain Reaction; RNA, Messenger; Skin Tests; Spirometry | 1998 |
Respiratory syncytial virus infection prolongs methacholine-induced airway hyperresponsiveness in ovalbumin-sensitized mice.
Topics: Animals; Body Weight; Bronchial Provocation Tests; Eosinophils; Female; Inflammation; Lung; Lymphocytes; Macrophages; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Respiratory Hypersensitivity; Respiratory Syncytial Virus Infections; Specific Pathogen-Free Organisms; Time Factors; Viral Plaque Assay | 1999 |
Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Eosinophils; Histocytochemistry; Hypersensitivity; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, SCID; Mice, Transgenic; Ovalbumin; Th1 Cells; Th2 Cells | 1999 |
Airway inflammation, exhaled nitric oxide, and severity of asthma in patients with western red cedar asthma.
Topics: Adult; Asthma; Bronchoconstrictor Agents; Cell Count; Eosinophils; Female; Forced Expiratory Volume; Humans; Inflammation; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Respiration; Respiratory System; Severity of Illness Index; Sputum; Trees | 1999 |
Dissociation of airway hyperresponsiveness from immunoglobulin E and airway eosinophilia in a murine model of allergic asthma.
Topics: Animals; Asthma; Bronchoconstrictor Agents; Cell Movement; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophilia; Humans; Immunoglobulin E; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Ovalbumin; Respiratory Hypersensitivity | 1999 |
Exhaled monoxides in asymptomatic atopic subjects.
Topics: Adolescent; Adult; Breath Tests; Bronchoconstrictor Agents; Carbon Monoxide; Female; Humans; Hypersensitivity, Immediate; Inflammation; Male; Methacholine Chloride; Nitric Oxide; Respiratory Function Tests | 1999 |
Airway inflammation and altered alveolar macrophage phenotype pattern after repeated low-dose allergen exposure of atopic asthmatic subjects.
Topics: Adult; Allergens; Antibodies, Monoclonal; Asthma; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Eosinophil Granule Proteins; Eosinophils; Female; Forced Expiratory Volume; Humans; Hypersensitivity, Immediate; Inflammation; Macrophages, Alveolar; Male; Methacholine Chloride; Poaceae; Pollen; Ribonucleases; Trees | 1999 |
IL-10 reduces grain dust-induced airway inflammation and airway hyperreactivity.
Topics: Animals; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dust; Inflammation; Interleukin-10; Lipopolysaccharides; Lung; Lung Diseases, Obstructive; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Monokines; Neutrophil Infiltration; Respiratory Tract Diseases; RNA, Messenger; Zea mays | 2000 |
Bronchial reactivity to cigarette smoke; relation to lung function, respiratory symptoms, serum-immunoglobulin E and blood eosinophil and leukocyte counts.
Topics: Adult; Aged; Bronchial Hyperreactivity; Cross-Sectional Studies; Eosinophils; Female; Forced Expiratory Volume; Humans; Immunoglobulin E; Inflammation; Leukocyte Count; Leukocytes; Male; Methacholine Chloride; Middle Aged; Nicotiana; Plants, Toxic; Regression Analysis; Smoke; Smoking; Vital Capacity | 2000 |
Modification of the inflammatory response to allergen challenge after exposure to bacterial lipopolysaccharide.
Topics: Aerosols; Allergens; Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cell Count; Evans Blue; Immunization; Immunoglobulin E; Immunoglobulin G; Inflammation; Lipopolysaccharides; Lung; Male; Methacholine Chloride; Ovalbumin; Rats; Rats, Inbred Strains; Respiratory Function Tests | 2000 |
IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization.
Topics: Aerosols; Animals; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cytokines; Electric Stimulation; Eosinophil Granule Proteins; Eosinophil Peroxidase; Eosinophilia; Female; Genetic Complementation Test; Genetic Therapy; Immunization; Inflammation; Interleukin-10; Leukotrienes; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Ovalbumin; Peroxidases; Respiratory Hypersensitivity; Ribonucleases; Specific Pathogen-Free Organisms; Trachea | 2000 |
IL-10 gene knockout attenuates allergen-induced airway hyperresponsiveness in C57BL/6 mice.
Topics: Adoptive Transfer; Allergens; Animals; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Immunoglobulins; In Vitro Techniques; Inflammation; Interleukin-10; Interleukin-13; Interleukin-4; Interleukin-5; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; Recombinant Proteins; Respiratory Hypersensitivity; Spleen; Th2 Cells | 2001 |
Inhibition of eosinophilic inflammation in allergen-challenged TNF receptor p55/p75--and TNF receptor p55-deficient mice.
Topics: Allergens; Animals; Antigens, CD; Bronchoalveolar Lavage Fluid; Cell Adhesion; Disease Models, Animal; Endothelium, Vascular; Eosinophils; Inflammation; Interleukin-5; Lung; Methacholine Chloride; Mice; Mice, Knockout; Mice, Transgenic; Microcirculation; Ovalbumin; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Splanchnic Circulation; Tumor Necrosis Factor-alpha | 2001 |
Mild exacerbations and eosinophilic inflammation in patients with stable, well-controlled asthma after 1 year of follow-up.
Topics: Administration, Inhalation; Administration, Topical; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Anti-Inflammatory Agents; Asthma; Blood Proteins; Bronchial Provocation Tests; Bronchodilator Agents; Budesonide; Eosinophil Granule Proteins; Eosinophils; Follow-Up Studies; Forced Expiratory Volume; Glucocorticoids; Humans; Inflammation; Leukocyte Count; Longitudinal Studies; Methacholine Chloride; Middle Aged; Peak Expiratory Flow Rate; Ribonucleases; Risk Factors | 2001 |
Airway inflammation and bronchial hyperresponsiveness after Mycoplasma pneumoniae infection in a murine model.
Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Interferon-gamma; Leukocyte Count; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mycoplasma pneumoniae; Pneumonia, Mycoplasma; RNA, Messenger | 2001 |
L-Selectin is required for the development of airway hyperresponsiveness but not airway inflammation in a murine model of asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Flow Cytometry; Humans; Immunoglobulin E; Inflammation; L-Selectin; Leukocyte Count; Lung; Methacholine Chloride; Mice; Mice, Inbred C57BL; Ovalbumin | 2001 |
How best to measure airway responsiveness.
Topics: Adenosine Monophosphate; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Humans; Inflammation; Methacholine Chloride | 2001 |
Eosinophil tissue recruitment to sites of allergic inflammation in the lung is platelet endothelial cell adhesion molecule independent.
Topics: Administration, Inhalation; Animals; Blood Cell Count; Bone Marrow Cells; Bronchial Hyperreactivity; Cell Adhesion; Cell Movement; Eosinophils; Extracellular Space; Female; Flow Cytometry; Humans; Immune Sera; Inflammation; Injections, Intraperitoneal; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Transgenic; Neutrophils; Platelet Endothelial Cell Adhesion Molecule-1; Protein Structure, Tertiary; Respiratory Hypersensitivity; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
CCSP modulates airway dysfunction and host responses in an Ova-challenged mouse model.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Chemokine CXCL2; Chemokines; Enzyme Inhibitors; Female; Histocytochemistry; Humans; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Knockout; Neutrophils; Ovalbumin; Peroxidase; Proteins; Uteroglobin | 2001 |
Construction of single-chain interleukin-12 DNA plasmid to treat airway hyperresponsiveness in an animal model of asthma.
Topics: Allergens; Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; COS Cells; Disease Models, Animal; Female; Genetic Therapy; Immunotherapy; Inflammation; Interleukin-12; Lung; Methacholine Chloride; Mice; Mice, Inbred C57BL; Plasmids; Transfection; Vaccines, DNA | 2001 |
Granulocyte depletion and dexamethasone differentially modulate airways hyperreactivity, inflammation, mucus accumulation, and secretion induced by rmIL-13 or antigen.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dexamethasone; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Eosinophils; Granulocytes; Immunohistochemistry; Inflammation; Interleukin-13; Lung; Male; Methacholine Chloride; Mice; Mucin 5AC; Mucins; Mucus; Peroxidase; Peroxidases; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Th1 Cells; Th2 Cells; Time Factors; Vinblastine | 2002 |
NO-steroids: potent anti-inflammatory drugs with bronchodilating activity in vitro.
Topics: Animals; Anti-Inflammatory Agents; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Inflammation; Methacholine Chloride; Models, Chemical; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Culture Techniques; Papaverine; Perfusion; Phosphodiesterase Inhibitors; Prednisolone; Steroids; Trachea; Vasodilator Agents | 2002 |
Intra-luminal exposure of murine airways to peroxynitrite causes inflammation but not hyperresponsiveness.
Topics: Acetylcholine; Animals; Bronchi; Bronchial Hyperreactivity; Inflammation; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Molsidomine; Peroxynitrous Acid; Trachea; Tyrosine | 2002 |
Airways inflammation after exposure in a swine confinement building during cleaning procedure.
Topics: Animal Husbandry; Animals; Bronchial Hyperreactivity; Bronchitis; Dust; Humans; Inflammation; Interleukin-8; Leukocyte Count; Methacholine Chloride; Neutrophils; Occupational Diseases; Occupational Exposure; Respiratory Protective Devices; Respiratory Tract Diseases; Swine | 2002 |
Airway hyperresponsiveness to adenosine induced by lipopolysaccharide in Brown Norway rats.
Topics: Adenosine; Animals; Anti-Asthmatic Agents; Biomarkers; Blood Pressure; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cromolyn Sodium; Dose-Response Relationship, Drug; Drug Synergism; Heart Rate; Inflammation; Lipopolysaccharides; Male; Mast Cells; Methacholine Chloride; Methysergide; Purinergic P1 Receptor Antagonists; Rats; Serotonin; Vasoconstrictor Agents | 2002 |
Airway and tissue mechanics in a murine model of asthma: alveolar capsule vs. forced oscillations.
Topics: Administration, Inhalation; Airway Resistance; Algorithms; Animals; Asthma; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Elasticity; Female; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Pulmonary Alveoli; Respiration, Artificial; Respiratory Function Tests; Respiratory Mechanics; Respiratory System | 2002 |
Airway inflammation and occurrence of delayed bronchoconstriction in exercise-induced asthma.
Topics: Adult; Asthma, Exercise-Induced; Biopsy; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Evaluation Studies as Topic; Exercise Test; Female; Forced Expiratory Volume; Histamine; Humans; Inflammation; Leukotrienes; Lymphocytes; Macrophages; Male; Mast Cells; Methacholine Chloride; Neutrophils; Severity of Illness Index; Time Factors | 1992 |
Airway responsiveness: new concepts and concerns.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Humans; Infant; Inflammation; Methacholine Chloride | 1992 |
The onset and recovery from airway hyperresponsiveness: relationship with inflammatory cell infiltrates and release of cytotoxic granule proteins.
Topics: Airway Resistance; Animals; Ascaris; Bronchoalveolar Lavage Fluid; Cytotoxicity, Immunologic; Granulocytes; Inflammation; Macaca fascicularis; Male; Methacholine Chloride; Proteins; Respiratory Hypersensitivity | 1992 |
Inflammatory cells and eicosanoid mediators in subjects with late asthmatic responses and increases in airway responsiveness.
Topics: Airway Resistance; Analysis of Variance; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Count; Eicosanoids; Female; Forced Expiratory Volume; Humans; Inflammation; Male; Methacholine Chloride; Skin Tests | 1992 |
Effect of epithelial denudation, inflammatory mediators and mast cell activation on the sensitivity of isolated human airways to methacholine.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Aged, 80 and over; Antibodies, Anti-Idiotypic; Dinoprost; Epithelium; Histamine; Humans; Hypersensitivity; Immunoglobulin E; In Vitro Techniques; Inflammation; Kinetics; Lung; Male; Mast Cells; Methacholine Chloride; Middle Aged; Muscle Contraction; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; SRS-A | 1991 |
Allergen-induced increase in airway responsiveness and inflammation in mild asthma.
Topics: Adult; Airway Resistance; Allergens; Analysis of Variance; Asthma; Bronchi; Eosinophils; Humans; Inflammation; Lymphocytes; Male; Methacholine Chloride; Pulmonary Alveoli; Rhinitis, Allergic, Perennial; Therapeutic Irrigation | 1990 |
Inflammatory markers in bronchoalveolar lavage and in bronchial biopsy in asthma during remission.
Topics: Adolescent; Adult; Asthma; Biopsy; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Epithelium; Female; Humans; Inflammation; Male; Mast Cells; Methacholine Chloride; Methacholine Compounds | 1990 |
Effects of inflammatory mediators on the responsiveness of isolated human airways to methacholine.
Topics: Aged; Bronchi; Dinoprost; Dose-Response Relationship, Drug; Female; Histamine; Humans; In Vitro Techniques; Inflammation; Male; Methacholine Chloride; Middle Aged; Muscle Contraction; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; SRS-A | 1990 |
Bronchial biopsies in asthma. An ultrastructural, quantitative study and correlation with hyperreactivity.
Topics: Adult; Asthma; Basement Membrane; Biopsy; Bronchi; Bronchoscopy; Epithelium; Female; Humans; Inflammation; Male; Methacholine Chloride; Methacholine Compounds | 1989 |
Importance of airway inflammation for late asthmatic reactions induced by toluene diisocyanate in sensitized subjects.
Topics: Adult; Asthma; Cyanates; Humans; Inflammation; Male; Methacholine Chloride; Methacholine Compounds; Respiratory System; Time Factors; Toluene 2,4-Diisocyanate | 1987 |
O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans.
Topics: Adult; Airway Resistance; Arachidonic Acid; Arachidonic Acids; Bronchi; Cell Count; Female; Humans; Inflammation; Male; Methacholine Chloride; Methacholine Compounds; Neutrophils; Ozone; Respiratory Tract Diseases; Therapeutic Irrigation | 1986 |
Mediators, airway responsiveness, and asthma.
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Dinoprost; Histamine; Humans; Inflammation; Lung; Methacholine Chloride; Methacholine Compounds; Prostaglandins; Prostaglandins F; SRS-A | 1985 |