methacholine chloride has been researched along with Hypersensitivity in 129 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (6.98) | 18.7374 |
| 1990's | 49 (37.98) | 18.2507 |
| 2000's | 40 (31.01) | 29.6817 |
| 2010's | 31 (24.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amaya, ED; Barranco, P; Coman, I; Domínguez-Ortega, J; Lluncor, M; López-Carrasco, V; Quirce, S | 1 |
| Ishii, M; Kawano, T; Miyasaka, T; Ohkawara, Y; Ohno, I; Ouchi, R; Takahashi, T; Takayanagi, M; Yoshida, H | 1 |
| Gauvreau, GM; Grasemann, H; Inman, MD; Khanna, N; North, ML; Scott, JA | 1 |
| Albuquerque, LL; Castro, JM; de Franco, M; de Lima, WT; Florsheim, E; Gomes, E; Lino-dos-Santos-Franco, A; Mirotti, L; Resende, RR; Ribeiro, OG; Russo, M | 1 |
| Cloots, RH; de Theije, CC; Hakvoort, TB; Köhler, SE; Lamers, WH; Poynter, ME; Sankaranarayanan, S; Terwindt, E; van Dijk, P | 1 |
| Hartney, JM; Robichaud, A | 1 |
| Amakye, DO; Cockcroft, DW; Davis, BE; Martin, AL; Peters, GE | 1 |
| Bush, A; Chaudry, RA; Crowley, S; Rosenthal, M | 1 |
| Berry, LJ; Fernandes, LB; Kicic, A; Larcombe, AN; Phan, JA; Sly, PD; Zosky, GR | 1 |
| Bar Yoseph, R; Bentur, L; Dabbah, H; Hakim, F; Livnat, G | 1 |
| Aliyeva, MI; Ather, JL; Bates, JH; Chung, M; Daphtary, NA; Dixon, AE; Forgione, PM; Georgsdottir, A; Hoyt, LR; Irvin, CG; Poynter, ME; Randall, MJ; Russell, SR; Suratt, BT | 1 |
| Kelada, SN | 1 |
| Guo, H; Hao, Y; Hui, Y; Ren, F; Wang, X; Zhao, L | 1 |
| Angino, A; Baldacci, S; Carrozzi, L; Di Pede, F; Maio, S; Pistelli, F; Polverino, E; Sherrill, D; Simoni, M; Viegi, G | 1 |
| Foster, WM; Garantziotis, S; He, YW; Hollingsworth, JW; Jia, W; Lalani, S; Li, Z; Liu, Z; Potts, EN | 1 |
| Boulet, LP; Day, A; Langdeau, JB; Turcotte, H | 1 |
| Bullens, D; El Bakkoury, M; Garcia, L; Jacquet, A; Marchand, C; Mattéotti, C; Vandenbranden, M; Walgraffe, D | 1 |
| Avila, L; Brehm, JM; Celedón, JC; Forno, E; Hollis, BW; Hunninghake, GM; Laskey, D; Litonjua, AA; Soto-Quiros, ME; Sylvia, JS; Weiss, ST | 1 |
| Adner, M; Dahlén, SE; Ellis, R; Inman, M; Neimert-Andersson, T; Nilsson, G; Ryrfeldt, A; Swedin, L | 1 |
| Fujimoto, S; Kanazawa, H; Tanaka, J; Yamamoto, T; Yoshikawa, T | 1 |
| Agrawal, DK; Makinde, TO | 1 |
| Ackermann-Liebrich, U; Bettschart, RW; Bridevaux, PO; Brutsche, M; Curjuric, I; Dratva, J; Frey, M; Gerbase, MW; Knöpfli, B; Künzli, N; Pons, M; Rochat, T; Schindler, C; Schwartz, J; Zemp, E | 1 |
| Chung, YJ; Copeland, LB; Doerfler, DL; Ward, MD | 1 |
| Hong, SJ; Kim, BJ; Kim, BS; Kim, HB; Kim, JH; Lee, SY; Yoo, S; Yu, JH | 1 |
| Carlsen, KH; Devulapalli, CS; Håland, G; Lødrup Carlsen, KC; Mowinckel, P; Munthe-Kaas, MC; Sachs-Olsen, C | 1 |
| Choi, SJ; Kim, CK; Koh, YY; Lee, JK; Suh, DI | 1 |
| Bao, MJ; Cao, R; Chen, XP; Deng, YM; Dong, XW; He, JS; Jiang, JX; Li, FF; Xie, QM; Xie, YC; Yan, XF | 1 |
| Bao, ZS; Dong, XW; Guan, Y; Hong, L; Tan, GL; Xie, QM; Zheng, HS | 1 |
| Fehrenbach, H; Garn, H; Kerzel, S; Maier, RF; Preisser, K; Rogosch, T; Schroeder, HW; Wagner, J; Yildirim, AÖ; Zemlin, M | 1 |
| Ellis, R; Feng, M; Inman, MD; Lu, WY; Wang, S; Wattie, J; Xiang, YY | 1 |
| Carter, L; Gelfand, EW; Hicken, E; Jackson, L; Jia, Y; Robinson, J; Shin, YS; Shiraishi, Y; Takeda, K; Wang, M; Wright, AD | 1 |
| Driehuys, B; Foster, WM; Kaushik, SS; Nouls, J; Potts, EN; Slipetz, DM; Thomas, AC | 1 |
| Bahaie, NS; Blumenthal, MN; Ge, XN; Greenberg, Y; Ha, SG; Kang, BN; Puri, KD; Rao, SP; Reza Hosseinkhani, M; Sriramarao, P | 1 |
| Hershey, GK; Le Cras, TD; Mushaben, EM; Nichols, WC; Pauciulo, MW | 1 |
| Chen, FH; Chen, H; Chen, ZG; Ji, JZ; Li, HT; Zhang, TT; Zou, XL | 1 |
| Herrmann, E; Reinmüller, W; Rose, MA; Rosewich, M; Schulze, J; Zielen, S | 1 |
| Björkstén, B; Boman, G; Janson, C; Jõgi, R | 1 |
| Becklake, MR; Ernst, P; Ghezzo, H | 1 |
| Inami, M; Kamata, T; Kimura, M; Murata, K; Nakayama, T; Shimizu, C; Sugaya, K; Taniguchi, M; Wang, CR; Yamashita, M | 1 |
| Amemiya, T; Fujimura, M; Ishiura, Y; Kurashima, K; Myou, S; Nobata, K | 1 |
| Lierl, MB | 1 |
| Covar, RA; Martin, RJ; Murphy, J; Silkoff, PE; Spahn, JD; Sundstrom, DA; Szefler, SJ; Young, DA | 1 |
| Abo, M; Fujimura, M; Ishiura, Y; Katayama, N; Kita, T; Myou, S; Nakao, S; Nishitsuji, M; Nomura, S; Oribe, Y; Yoshimi, Y | 1 |
| Gama Landgraf, R; Jancar, S; Sirois, P; Steil, AA | 1 |
| Bakhle, YS; Jancar, S; Kwasniewski, FH; Landgraf, RG | 1 |
| Boulet, LP; Cockcroft, DW; Davis, BE; Deschesnes, F; Gauvreau, GM; O'Byrne, PM; Watson, RM | 1 |
| Chung, YJ; Coates, NH; Copeland, L; Selgrade, MK; Vesper, SJ; Viana, ME; Ward, MD | 1 |
| Gratziou, C; Papapetropoulos, A; Roussos, C; Simoes, DC; Xanthou, G | 1 |
| Feltis, B; Johns, DP; Orsida, BE; Reid, DW; Ryan, VA; Walters, EH; Ward, C | 1 |
| Chen, B; Dowell, M; Fredberg, JJ; Lakser, O; Liu, G; Mitchell, RW; Pinto, LH; Shardonofsky, F; Solway, J | 1 |
| Arata, S; Gabazza, EC; Homma, I; Iwase, M; Kimura, H; Miyamoto, K; Nyui, M; Sakai, Y | 1 |
| Ciprandi, G; Cirillo, I; Klersy, C; Marseglia, GL; Pallestrini, E; Tosca, M; Vizzaccaro, A | 1 |
| Bradbury, JA; Card, JW; Carey, MA; DeGraff, LM; Foley, JF; Graves, JP; Lih, FB; Moorman, MP; Morgan, DL; Zeldin, DC; Zhao, Y | 1 |
| Duong, M; Gauvreau, GM; Kawayama, T; Killian, KJ; O'Byrne, PM; Watson, RM; Yoshida, M | 1 |
| Choi, SH; Kim, DK; Koh, YY; Yoo, Y; Yu, J | 1 |
| Arm, JP; Bonventre, JV; Cho, W; Leff, AR; Meliton, AY; Muñoz, NM | 1 |
| Anderson, WH; Barnes, K; Carlsen, K; Gerritsen, J; Helms, PJ; Klotsman, M; Lenney, W; Ortega, HG; Pillai, SG; Silverman, M; Sly, P; Sundy, J; Tang, Y; Tsanakas, J; van den Oord, E; von Berg, A; Whyte, M | 1 |
| Broadley, KJ; Fernandez-Rodriguez, S; Ford, WR; Kidd, EJ | 1 |
| Coskun, NF; Duran, C; Ediger, D; Ercan, I; Ersoy, C; Erturk, E; Guclu, M; Imamoglu, S; Kiyici, S; Saglam, DA; Selimoglu, H; Tuncel, E | 1 |
| Amacher, A; Hammer, J; Ramser, M; Trachsel, D | 1 |
| Lee, LY; Lin, RL; Wiggers, ME; Zhang, G | 1 |
| Butler, J; Downes, H; Hanifin, JM; Hirshman, CA; Peters, J | 1 |
| Chonan, T; Fuyuki, T; Ida, S; Ishihara, T; Mue, S; Ohmi, T; Sato, K; Shindoh, C; Tamura, G; Yamauchi, K | 1 |
| Baruth, H; Czyzewski, LB; Hooper, A; Medford, A; Miller, D; Salvador, RA; van Trabert, T; Welton, AF; Yaremko, B | 1 |
| Abramson, MJ; Forbes, AB; Harrap, SB; Kutin, JJ; Lanigan, A; Raven, J; van Herwerden, L; Walters, EH; Wong, ZY | 1 |
| Coates, AL; Dagenais, S; Davis, GM; Hamilton, EF; Joshi, AK; Kramer, MS; Michoud, MC; Moshonas, D; Nuwayhid, B; Papageorgiou, A | 1 |
| Abbritti, G; Brugnami, G; Marabini, A; Siracusa, A | 1 |
| Ackerman, SJ; Burch, R; Coyle, AJ; Irvin, CG; Proud, D | 1 |
| Annema, JT; Koëter, GH; O'Connor, GT; Postma, DS; Rijcken, B; Sparrow, D; Weiss, ST | 1 |
| Antó, JM; Codina, R; Morell, F; Roca, J; Rodrigo, MJ; Rodríguez-Roisín, R; Sabrià, J; Sunyer, J | 1 |
| Antolini, I; Boner, AL; Peroni, DG; Vallone, G; Warner, JO | 1 |
| Fujimura, M; Matsuda, T; Mizuhashi, K; Saito, M; Songür, N; Xiu, QY | 1 |
| Britton, J; Kinnear, W; Knox, A; Pavord, I; Richards, K; Tattersfield, A; Wahedna, I; Weiss, S; Wisniewski, A | 1 |
| White, MV | 1 |
| Manzini, S; Page, CP; Riccio, MM | 1 |
| Agabiti, N; Corbo, GM; Dell'Orco, V; Forastiere, F; Kriebel, D; Pistelli, R | 1 |
| Averill, FJ; Chilton, FH; Fonteh, AN; Hubbard, WC; Liu, MC; Triggiani, M | 1 |
| Antó, JM; Castellsagué, J; Roca, J; Soriano, JB; Sunyer, J | 1 |
| Benovic, JL; Fish, JE; Penn, RB; Peters, SP; Pollice, M; Shaver, JR; Zangrilli, JG | 1 |
| Balbo, A; Crimi, E; Frangova, V; Oddera, S; Rossi, GA; Sacco, O; Silvestri, M | 1 |
| Cernadas, M; Christiani, DC; De Sanctis, GT; Donovan, C; Finn, PW; Katona, I; Kobzik, L; Krinzman, SJ; Listman, J; Mark, D; Nassr, K; Perkins, DL; Wang, Y | 1 |
| Doré, CJ; Silverman, M; Wilson, NM | 1 |
| Brown, K; Seaton, A; Soutar, A | 1 |
| Antó, JM; Kogevinas, M; Muñoz, A; Soriano, JB; Sunyer, J; Tobias, A | 1 |
| Angelini, B; Cohen, S; Doyle, WJ; Seroky, J; Skoner, DP; Van Deusen, MA | 1 |
| Bradley, KL; Gelfand, EW; Hamelmann, E; Schwarze, J; Takeda, K | 1 |
| Björnsson, E; Enander, I; Håkanson, L; Janson, C | 1 |
| Gelfand, EW; Hamelmann, E; Irvin, CG; Larsen, GL; Oshiba, A; Schwarze, J; Takeda, K | 1 |
| Ikuta, K; Ishii, S; Komagata, Y; Kume, K; Maki, K; Miyazaki, J; Nagase, T; Nakatani, N; Ouchi, Y; Shimizu, T; Tashiro, F; Uozumi, N | 1 |
| Connolly, MJ; Renwick, DS | 1 |
| Hall, GL; Peták, F; Sly, PD | 1 |
| Fujimura, M; Hashimoto, T; Ishiura, Y; Kamio, Y; Kasahara, K; Matsuda, T; Myou, S; Yasui, M | 1 |
| Håkansson, L; Heinrich, C; Rak, S; Venge, P | 1 |
| Corey, P; Hanania, NA; Senathirajah, N; Silverman, F; Tarlo, SM; Urch, B; Zamel, N | 1 |
| Chapman, ID; Chilvers, ER; Handley, DA; Morley, J; Templeton, AG | 1 |
| Hofman, G; Hofstra, CL; Jardieu, PM; Nijkamp, FP; Van Ark, I; Van Oosterhout, AJ | 1 |
| Aronica, MA; Boothby, M; Chen, J; Correa, V; Goenka, S; Mora, AL; Sheller, JR; Youn, J | 1 |
| Burney, P; Chinn, S; Jarvis, D; Luczynska, C | 1 |
| Berry, G; DeKruyff, RH; Hansen, G; Umetsu, DT | 1 |
| Rak, S; Venge, P; Woschnagg, C | 1 |
| Hickey, B; Li, X; Orsida, BE; Thien, F; Walters, EH; Wilson, JW | 1 |
| Banfi, P; Bossi, R; Braga, PC; Castelli, C; Filipazzi, V | 1 |
| Baradaran-Hosseini, E; Puddington, L; Schramm, CM; Stengel, P; Thrall, RS; Whiteley, HE; Wolyniec, WW; Yiamouyiannis, CA | 1 |
| Ekström, K; Hedlin, G; Herrmann, B; Hjern, A; Montan, PG; van Hage-Hamsten, M | 1 |
| Hansen, HS; Hansen, NC; Lambrechtsen, J; Rasmussen, F; Siersted, HC | 1 |
| Arribas, J; Colás, C; Duce, F; Larraga, R; Olivares, JL; Pastor, I; Sebastián, A | 1 |
| Bradfield, JF; Enright, E; Justice, JP; Sigounas, A; Sur, S; van Scott, MR | 1 |
| Holt, PG; Sly, PD; Tulić, MK; Wale, JL | 1 |
| Collins, RD; Dworski, R; Graham, BS; Jarzecka, K; Mitchell, DB; Peebles, RS; Sheller, JR | 1 |
| Alarie, Y; Braun, A; Daser, A; Fabel, H; Glaab, T; Neuhaus-Steinmetz, U; Renz, H | 1 |
| Cho, SH; Jee, YK; Jeong, JH; Kim, CK; Kim, YK; Kim, YY; Koh, YY; Min, KU | 1 |
| Celly, C; Chapman, RW; House, A; Kreutner, W; Young, S | 1 |
| Collins, RD; Furlong, J; Graham, BS; Hashimoto, K; Jarzecka, K; Mitchell, DB; Peebles, RS; Sheller, JR | 1 |
| Gutiérrez, V; Marín, MJ; Prieto, L; Sánchez-Toril, F | 1 |
| Go, K; Namimatsu, A; Okuda, M; Tanimoto, H | 1 |
| Diamond, EL; Eggleston, PA; Evans, R; Fish, JE; Newill, CA; Prenger, VL; Wei, Q | 1 |
| Phagoo, SB; Silverman, M; Wilson, NM | 1 |
| Leung, DY; Tollerud, DJ; Weiss, ST | 1 |
| Clough, J; Lemanske, RF; Ritter, M; Sorkness, R | 1 |
| Annesi, I; Dore, MF; Frette, C; Kauffmann, F; Neukirch, F; Oryszczyn, MP | 1 |
| Bonta, I; De Jongste, J; Jongejan, R; Kerrebijn, K; Raatgeep, R; Stijnen, T | 1 |
| Bewtra, AK; Biven, RE; Davé, NK; Degan, J; Hopp, RJ; Townley, RG | 1 |
| Boehm, S; Doyle, WJ; Skoner, DP | 1 |
| Austin, DR; Chan, SC; Hanifin, JM; Hirshman, CA; Leu, DB; Veith, L | 1 |
| Chai, H; Dunn, K; Rohatgi, N | 1 |
| Dieges, PH; Gerth Van Wijk, R | 1 |
| Armstrong, PJ; Derksen, FJ; Robinson, NE; Slocombe, RF | 1 |
| Casale, TB; Hunninghake, GW; Metzger, WJ; Richerson, HB; Trapp, S; Wood, D; Zavala, D | 1 |
10 trial(s) available for methacholine chloride and Hypersensitivity
| Article | Year |
|---|---|
Refractoriness to inhaled mannitol 3 hours after allergen challenge.
Topics: Administration, Inhalation; Adult; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Male; Mannitol; Methacholine Chloride; Young Adult | 2013 |
Relations between exhaled nitric oxide and measures of disease activity among children with mild-to-moderate asthma.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Blood Proteins; Bronchoconstrictor Agents; Budesonide; Child; Child, Preschool; Cohort Studies; Eosinophil Granule Proteins; Eosinophils; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Immunoglobulin E; Leukocyte Count; Male; Methacholine Chloride; Nedocromil; Nitric Oxide; Respiration; Respiratory Function Tests; Ribonucleases; Severity of Illness Index; Skin Tests; Spirometry; Statistics, Nonparametric | 2003 |
Effects of inhaled ciclesonide on circulating T-helper type 1/T-helper type 2 cells in atopic asthmatics after allergen challenge.
Topics: Administration, Inhalation; Adult; Allergens; Analysis of Variance; Asthma; Biomarkers; Bronchial Provocation Tests; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Eosinophils; Female; Flow Cytometry; Glucocorticoids; Humans; Hypersensitivity; Interferon-gamma; Interleukin-4; Lymphocyte Count; Male; Methacholine Chloride; Pregnenediones; Sputum | 2006 |
The value of exhaled nitric oxide in predicting bronchial hyperresponsiveness in children.
Topics: Adolescent; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Exercise Test; Exhalation; Female; Humans; Hypersensitivity; Male; Methacholine Chloride; Nitric Oxide; Plethysmography, Whole Body; Predictive Value of Tests; Spirometry | 2008 |
Factors influencing the occurrence of airway hyperreactivity in the general population: the importance of atopy and airway calibre.
Topics: Adolescent; Adult; Age Factors; Aged; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Male; Methacholine Chloride; Middle Aged; Skin Tests; Smoking | 1994 |
Nasal cholinergic hyperresponsiveness in atopic subjects studied out of season.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Female; Humans; Hypersensitivity; Lactoferrin; Male; Methacholine Chloride; Middle Aged; Nasal Cavity; Nasal Mucosa; Nasal Provocation Tests; Proteins; Seasons; Serum Albumin | 1993 |
Effect of exposure to low levels of ozone on the response to inhaled allergen in allergic asthmatic patients.
Topics: Administration, Inhalation; Adolescent; Adult; Air Pollutants; Allergens; Asthma; Bronchial Provocation Tests; Cross-Over Studies; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Male; Methacholine Chloride; Middle Aged; Ozone; Prospective Studies; Single-Blind Method; Skin Tests; Vital Capacity | 1998 |
Levodropropizine (LD) activity in allergic asthmatic patients, challenged with ultrasonically nebulized distilled water, metacholine and allergen-induced bronchospasm.
Topics: Administration, Oral; Adolescent; Adult; Allergens; Antitussive Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchial Spasm; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypersensitivity; Male; Methacholine Chloride; Middle Aged; Nebulizers and Vaporizers; Placebos; Propylene Glycols; Ultrasonic Therapy; Water | 1994 |
Physiologic responses to intranasal dose-response challenges with histamine, methacholine, bradykinin, and prostaglandin in adult volunteers with and without nasal allergy.
Topics: Adolescent; Adult; Bradykinin; Dinoprost; Dose-Response Relationship, Drug; Ear; Forced Expiratory Volume; Histamine; Humans; Hypersensitivity; Male; Methacholine Chloride; Nasal Mucosa; Nasal Provocation Tests; Prostaglandin D2; Pulmonary Ventilation; Reference Values; Rhinitis | 1990 |
In vivo diagnostic testing and immunotherapy for allergy. Report I, Part I, of the allergy panel. Council on Scientific Affairs.
Topics: Bronchial Provocation Tests; Clinical Trials as Topic; Food Hypersensitivity; Humans; Hypersensitivity; Immunotherapy; Methacholine Chloride; Methacholine Compounds; Physical Exertion; Skin Tests | 1987 |
119 other study(ies) available for methacholine chloride and Hypersensitivity
| Article | Year |
|---|---|
Relationship between upper airway diseases, exhaled nitric oxide, and bronchial hyperresponsiveness to methacholine.
Topics: Adult; Asthma; Asthma, Aspirin-Induced; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cross-Sectional Studies; Female; Humans; Hypersensitivity; Male; Methacholine Chloride; Middle Aged; Nasal Polyps; Nitric Oxide; Prospective Studies; Rhinitis; Smoking; Spirometry | 2019 |
Maternal Separation as Early-Life Stress Causes Enhanced Allergic Airway Responses by Inhibiting Respiratory Tolerance in Mice.
Topics: Animals; Corticosterone; Cytokines; Female; Hypersensitivity; Immune Tolerance; Immunoglobulin E; Lung; Lymph Nodes; Maternal Deprivation; Methacholine Chloride; Mice, Inbred BALB C; Mucus; Ovalbumin; Pneumonia; Respiratory Hypersensitivity; Stress, Psychological; T-Lymphocytes, Regulatory; Th2 Cells | 2018 |
Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma.
Topics: Adolescent; Adult; Animals; Asthma; Disease Models, Animal; Eflornithine; Female; Humans; Hypersensitivity; Inflammation; Lung; Male; Methacholine Chloride; Mice; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Ovalbumin; Polyamines; Spermine; Sputum; Young Adult | 2013 |
Role of m2 muscarinic receptor in the airway response to methacholine of mice selected for minimal or maximal acute inflammatory response.
Topics: Animals; Hypersensitivity; In Vitro Techniques; Methacholine Chloride; Mice; Models, Biological; Pneumonia; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Respiration; Trachea | 2013 |
Ablation of Arg1 in hematopoietic cells improves respiratory function of lung parenchyma, but not that of larger airways or inflammation in asthmatic mice.
Topics: Airway Resistance; Animals; Arginase; Asthma; Blotting, Western; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Chemokines; Cytokines; Dendritic Cells; Female; Gene Expression Profiling; Hypersensitivity; Immunoenzyme Techniques; Lung; Macrophages; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; Ovalbumin; Pneumonia; Real-Time Polymerase Chain Reaction; Respiratory System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2013 |
Assessment of airway hyperresponsiveness in mouse models of allergic lung disease using detailed measurements of respiratory mechanics.
Topics: Animals; Asthma; Disease Models, Animal; Humans; Hypersensitivity; Lung; Methacholine Chloride; Mice; Respiratory Mechanics | 2013 |
Reduced forced expiratory flow but not increased exhaled nitric oxide or airway responsiveness to methacholine characterises paediatric sickle cell airway disease.
Topics: Adolescent; Airway Obstruction; Anemia, Sickle Cell; Asthma; Breath Tests; Case-Control Studies; Child; Eosinophils; Female; Forced Expiratory Flow Rates; Humans; Hypersensitivity; Immunoglobulin E; Leukocyte Count; Lung; Male; Methacholine Chloride; Nitric Oxide; Spirometry; Statistics, Nonparametric | 2014 |
Rhinovirus exacerbates house-dust-mite induced lung disease in adult mice.
Topics: Animals; Antibodies, Viral; Bronchoalveolar Lavage; Female; Hypersensitivity; Interleukin-13; Lung Diseases; Methacholine Chloride; Mice; Nasal Mucosa; Pyroglyphidae; Respiratory Function Tests; Rhinovirus | 2014 |
Bronchial Reactivity, Inflammatory and Allergic Parameters, and Vitamin D Levels in Children With Asthma.
Topics: Adolescent; Asthma; Biomarkers; Bronchial Provocation Tests; Bronchoconstrictor Agents; C-Reactive Protein; Child; Eosinophils; Female; Humans; Hypersensitivity; Immunoglobulin E; Inflammation Mediators; Leukocyte Count; Male; Methacholine Chloride; Nitric Oxide; Pulmonary Elimination; Spirometry; Vitamin D | 2015 |
Weight Loss Decreases Inherent and Allergic Methacholine Hyperresponsiveness in Mouse Models of Diet-Induced Obese Asthma.
Topics: Animals; Asthma; Bacteria; Bariatric Surgery; Bronchial Hyperreactivity; Cytokines; Diet; Disease Models, Animal; Hypersensitivity; Inflammation Mediators; Intestines; Male; Methacholine Chloride; Mice, Inbred C57BL; Mice, Obese; Obesity; Weight Loss | 2016 |
Plethysmography Phenotype QTL in Mice Before and After Allergen Sensitization and Challenge.
Topics: Allergens; Animals; Asthma; Disease Models, Animal; Gene-Environment Interaction; Humans; Hypersensitivity; Immunization; Lung; Methacholine Chloride; Mice; Plethysmography; Pyroglyphidae; Quantitative Trait Loci | 2016 |
Oral administration of Lactobacillus paracasei L9 attenuates PM2.5-induced enhancement of airway hyperresponsiveness and allergic airway response in murine model of asthma.
Topics: Administration, Oral; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Disease Models, Animal; Eosinophils; Female; Hypersensitivity; Immunotherapy; Lacticaseibacillus paracasei; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Particulate Matter; Probiotics; Th1 Cells; Th2 Cells | 2017 |
Urban residence is associated with bronchial hyperresponsiveness in Italian general population samples.
Topics: Adolescent; Adult; Age Distribution; Aged; Analysis of Variance; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Cross-Sectional Studies; Environmental Pollution; Female; Humans; Hypersensitivity; Incidence; Italy; Logistic Models; Male; Methacholine Chloride; Middle Aged; Odds Ratio; Probability; Respiratory Function Tests; Risk Factors; Sampling Studies; Severity of Illness Index; Sex Distribution; Skin Tests; Smoking; Urban Population; Young Adult | 2009 |
The extracellular matrix protein mindin regulates trafficking of murine eosinophils into the airspace.
Topics: Animals; Asthma; Cell Adhesion; Cell Movement; Eosinophils; Extracellular Matrix Proteins; Hypersensitivity; Immunoglobulin E; In Vitro Techniques; Integrin alpha4beta1; Interleukin-13; Interleukin-4; Lung; Macrophage-1 Antigen; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ovalbumin | 2009 |
Gender differences in the prevalence of airway hyperresponsiveness and asthma in athletes.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Chi-Square Distribution; Exercise; Family Practice; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Male; Methacholine Chloride; Prevalence; Retrospective Studies; Sex Factors; Sports; Surveys and Questionnaires | 2009 |
A hypoallergenic variant of Der p 1 as a candidate for mite allergy vaccines.
Topics: Allergens; Animals; Antigens, Dermatophagoides; Arthropod Proteins; Basophils; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Cell Line, Tumor; Cloning, Molecular; Cysteine Endopeptidases; Disease Models, Animal; Eosinophilia; Female; Humans; Hypersensitivity; Immunoglobulin E; Interferon-gamma; Interleukin-5; Methacholine Chloride; Mice; Mice, Inbred BALB C; Pyroglyphidae; Rats; Recombinant Proteins; T-Lymphocytes; Vaccines | 2009 |
Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica.
Topics: Adolescent; Anti-Inflammatory Agents; Asthma; Biomarkers; Bronchial Provocation Tests; Bronchoconstrictor Agents; Child; Costa Rica; Eosinophils; Female; Forced Expiratory Volume; Hospitalization; Humans; Hypersensitivity; Immunoglobulin E; Leukocyte Count; Male; Methacholine Chloride; Multivariate Analysis; Severity of Illness Index; Spirometry; Vitamin D | 2009 |
Prostaglandin modulation of airway inflammation and hyperresponsiveness in mice sensitized without adjuvant.
Topics: Adjuvants, Immunologic; Animals; Bronchoalveolar Lavage; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cysteine; Cytokines; Female; Hypersensitivity; Immunization; Inflammation; Leukotrienes; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Prostaglandins; Respiratory System | 2010 |
Gene polymorphism of epidermal growth factor receptor and airway hyperresponsiveness in young allergic subjects without respiratory symptoms.
Topics: Adolescent; Adult; Alleles; Bronchial Hyperreactivity; ErbB Receptors; Female; Gene Frequency; Genotype; Haplotypes; Humans; Hypersensitivity; Introns; Male; Methacholine Chloride; Models, Genetic; Odds Ratio; Polymorphism, Genetic; Polymorphism, Single Nucleotide | 2010 |
Increased expression of angiopoietins and Tie2 in the lungs of chronic asthmatic mice.
Topics: Angiopoietin-1; Angiopoietin-2; Animals; Asthma; Gene Expression Regulation; Hypersensitivity; Inflammation; Macrophages; Methacholine Chloride; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Models, Biological; Ovalbumin; Receptor Protein-Tyrosine Kinases; Receptor, TIE-2; Vascular Endothelial Growth Factor A | 2011 |
Determinants of change in airway reactivity over 11 years in the SAPALDIA population study.
Topics: Adult; Aged; Bronchial Provocation Tests; Cohort Studies; Female; Humans; Hypersensitivity; Lung Diseases; Male; Methacholine Chloride; Middle Aged; Prevalence; Respiratory Hypersensitivity; Smoking; Spirometry; Surveys and Questionnaires; Switzerland | 2011 |
A comparison of the allergic responses induced by Penicillium chrysogenum and house dust mite extracts in a mouse model.
Topics: Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Immunologic; Hypersensitivity; Immunoglobulin E; Intubation, Intratracheal; L-Lactate Dehydrogenase; Methacholine Chloride; Mice; Mice, Inbred BALB C; Penicillium chrysogenum; Pyroglyphidae | 2010 |
Association between obesity and the prevalence of allergic diseases, atopy, and bronchial hyperresponsiveness in Korean adolescents.
Topics: Adolescent; Asthma; Body Mass Index; Bronchial Hyperreactivity; Cross-Sectional Studies; Dermatitis, Atopic; Eosinophils; Female; Humans; Hypersensitivity; Immunoglobulin E; Leukocyte Count; Male; Methacholine Chloride; Obesity; Prevalence; Republic of Korea; Respiratory Function Tests; Respiratory Sounds; Sex Factors; Skin Tests | 2011 |
Diagnostic value of exhaled nitric oxide in childhood asthma and allergy.
Topics: Asthma; Breath Tests; Child; Exhalation; Feasibility Studies; Female; Follow-Up Studies; Humans; Hypersensitivity; Immunization; Male; Methacholine Chloride; Nitric Oxide; Sensitivity and Specificity; Skin Tests | 2010 |
Bronchial hyperresponsiveness to methacholine and adenosine monophosphate and the degree of atopy in children with allergic rhinitis.
Topics: Adenosine Monophosphate; Adolescent; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Female; Humans; Hypersensitivity; Male; Methacholine Chloride; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal | 2011 |
M(3) muscarinic receptor antagonist bencycloquidium bromide attenuates allergic airway inflammation, hyperresponsiveness and remodeling in mice.
Topics: Airway Remodeling; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bronchoalveolar Lavage Fluid; Chemokines; Eosinophilia; Female; Gene Expression Regulation; Hypersensitivity; Inflammation; Lung; Matrix Metalloproteinases; Methacholine Chloride; Mice; Pneumonia; Receptor, Muscarinic M3; Respiratory System; RNA, Messenger | 2011 |
Inhibition of airway inflammation, hyperresponsiveness and remodeling by soy isoflavone in a murine model of allergic asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Collagen; Eosinophils; Female; Glycine max; Hypersensitivity; Inflammation; Interferon-gamma; Interleukin-4; Interleukin-5; Isoflavones; Lung; Matrix Metalloproteinase 9; Methacholine Chloride; Mice; Mice, Inbred ICR; Mucus; Ovalbumin; Peroxidase; Respiratory System; Superoxide Dismutase; Tissue Inhibitor of Metalloproteinase-1 | 2011 |
A single DH gene segment is sufficient for the establishment of an asthma phenotype in a murine model of allergic airway inflammation.
Topics: Allergens; Animals; Asthma; B-Lymphocytes; Bronchial Hyperreactivity; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hypersensitivity; Immunoglobulin E; Immunoglobulin G; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Ovalbumin | 2011 |
Effects of furosemide on allergic asthmatic responses in mice.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Furosemide; Goblet Cells; Hypersensitivity; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; T-Lymphocytes; Treatment Outcome | 2011 |
Inhibition of Pim1 kinase activation attenuates allergen-induced airway hyperresponsiveness and inflammation.
Topics: Allergens; Animals; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Female; Goblet Cells; Hypersensitivity; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Pneumonia; Proto-Oncogene Proteins c-pim-1; Respiratory Hypersensitivity | 2012 |
Effects of corticosteroid treatment on airway inflammation, mechanics, and hyperpolarized ³He magnetic resonance imaging in an allergic mouse model.
Topics: Adrenal Cortex Hormones; Airway Resistance; Animals; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Dexamethasone; Disease Models, Animal; Elasticity; Helium; Hypersensitivity; Isotopes; Lung; Magnetic Resonance Imaging; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Models, Biological; Ovalbumin; Pulmonary Ventilation; Respiratory Mechanics | 2012 |
The p110δ subunit of PI3K regulates bone marrow-derived eosinophil trafficking and airway eosinophilia in allergen-challenged mice.
Topics: Adenine; Animals; Asthma; Bone Marrow Cells; Cell Adhesion; Cell Movement; Chemokine CCL11; Class I Phosphatidylinositol 3-Kinases; Eosinophilia; Eosinophils; Hypersensitivity; Intercellular Adhesion Molecule-1; Macrophage-1 Antigen; Methacholine Chloride; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Respiratory System; RNA Interference; RNA, Small Interfering; Vascular Cell Adhesion Molecule-1 | 2012 |
Chronic allergic inflammation causes vascular remodeling and pulmonary hypertension in BMPR2 hypomorph and wild-type mice.
Topics: Analysis of Variance; Animals; Arterioles; Blood Pressure; Blotting, Western; Bone Morphogenetic Protein Receptors, Type II; Bronchoalveolar Lavage; DNA Primers; Enzyme-Linked Immunosorbent Assay; Genotype; Hypersensitivity; Hypertension, Pulmonary; Immunohistochemistry; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mutation; Polymerase Chain Reaction; Pyroglyphidae; Signal Transduction | 2012 |
Neutralization of TSLP inhibits airway remodeling in a murine model of allergic asthma induced by chronic exposure to house dust mite.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dendritic Cells; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; GATA3 Transcription Factor; Homeostasis; Hypersensitivity; Inflammation; Interleukin-13; Interleukin-4; Methacholine Chloride; Mice; Mice, Inbred BALB C; Pyroglyphidae; Th2 Cells; Thymic Stromal Lymphopoietin | 2013 |
Bronchial allergen challenges in children - safety and predictors.
Topics: Adolescent; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Preschool; Exhalation; Female; Humans; Hypersensitivity; Immunoglobulin E; Male; Methacholine Chloride; Nitric Oxide; Predictive Value of Tests; Pyroglyphidae; Respiratory Function Tests; Retrospective Studies; ROC Curve; Sensitivity and Specificity | 2013 |
Serum eosinophil cationic protein (S-ECP) in a population with low prevalence of atopy.
Topics: Adult; Asthma; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Case-Control Studies; Chi-Square Distribution; Eosinophil Granule Proteins; Female; Humans; Hypersensitivity; Immunoglobulin E; Linear Models; Male; Methacholine Chloride; Prevalence; Ribonucleases | 2002 |
Risk factors for bronchial hyperresponsiveness in late childhood and early adolescence.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Hypersensitivity; Male; Methacholine Chloride; Prevalence; Prospective Studies; Puberty; Quebec; Residence Characteristics; Risk Factors; Skin Tests | 2002 |
src homology 2 domain-containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation.
Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes; Cell Differentiation; Cross-Linking Reagents; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Enzyme-Linked Immunosorbent Assay; Eosinophils; Flow Cytometry; Heterozygote; Hypersensitivity; Immunoblotting; Inflammation; Interleukin-13; Interleukin-6; Intracellular Signaling Peptides and Proteins; Mast Cells; Methacholine Chloride; Mice; Mice, Inbred C3H; Microscopy, Fluorescence; Mutation; Phenotype; Precipitin Tests; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Interleukin-4; Signal Transduction; src Homology Domains; T-Lymphocytes; Th1 Cells; Th2 Cells; Time Factors | 2003 |
Lack of adrenomedullin on antigen-induced bronchoconstriction in guinea pigs in vivo.
Topics: Adrenomedullin; Animals; Antigens; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Guinea Pigs; Histamine; Hypersensitivity; Male; Methacholine Chloride; Passive Cutaneous Anaphylaxis; Peptides; Respiration, Artificial | 2003 |
Exhaled nitric oxide: a useful aide in pediatric asthma management?
Topics: Anti-Asthmatic Agents; Asthma; Bronchoconstrictor Agents; Child, Preschool; Forced Expiratory Volume; Humans; Hypersensitivity; Immunoglobulin E; Infant; Methacholine Chloride; Nitric Oxide; Skin Tests | 2003 |
Potentiation of allergic bronchoconstriction by repeated exposure to formaldehyde in guinea-pigs in vivo.
Topics: Allergens; Animals; Antibodies; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Fixatives; Formaldehyde; Guinea Pigs; Hypersensitivity; Immunoglobulin E; Immunoglobulin G; Male; Methacholine Chloride; Ovalbumin; Passive Cutaneous Anaphylaxis | 2003 |
Modulation of allergic and immune complex-induced lung inflammation by bradykinin receptor antagonists.
Topics: Animals; Bradykinin; Bradykinin B1 Receptor Antagonists; Bradykinin B2 Receptor Antagonists; Bradykinin Receptor Antagonists; Bronchoconstriction; Eosinophils; Hypersensitivity; Immune Complex Diseases; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Pneumonia | 2004 |
Bronchoconstriction and endogenous nitric oxide in isolated lungs of spontaneously hypertensive rats.
Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents; Cell Degranulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypersensitivity; In Vitro Techniques; Lung; Male; Mast Cells; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ovalbumin; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred SHR; Rats, Wistar | 2004 |
The links between allergen skin test sensitivity, airway responsiveness and airway response to allergen.
Topics: Adult; Allergens; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Male; Methacholine Chloride; Models, Biological; Retrospective Studies; Skin Tests | 2005 |
Dose-dependent allergic responses to an extract of Penicillium chrysogenum in BALB/c mice.
Topics: Allergens; Animals; Antigens, Fungal; Asthma; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Immunologic; Female; Humans; Hypersensitivity; Immunoglobulin E; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Penicillium chrysogenum | 2005 |
Soluble guanylyl cyclase expression is reduced in allergic asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Enzyme Inhibitors; Guanylate Cyclase; Homeostasis; Hypersensitivity; Isoenzymes; Methacholine Chloride; Mice; Ovalbumin; Oxadiazoles; Quinoxalines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Soluble Guanylyl Cyclase | 2006 |
Inter-relationships between airway inflammation, reticular basement membrane thickening and bronchial hyper-reactivity to methacholine in asthma; a systematic bronchoalveolar lavage and airway biopsy analysis.
Topics: Asthma; Basement Membrane; Biopsy; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Case-Control Studies; Humans; Hypersensitivity; Methacholine Chloride; Regression Analysis; Reticulin; Spirometry | 2005 |
Tidal breathing pattern differentially antagonizes bronchoconstriction in C57BL/6J vs. A/J mice.
Topics: Airway Obstruction; Animals; Bronchoconstriction; Bronchoconstrictor Agents; Cholinergic Fibers; Female; Hypersensitivity; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Pulmonary Ventilation; Respiratory Mechanics; Respiratory System; Tidal Volume | 2006 |
Histamine type 1 receptor deficiency reduces airway inflammation in a murine asthma model.
Topics: Animals; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Histocytochemistry; Hypersensitivity; Immunoglobulin E; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Receptors, Histamine H1; Specific Pathogen-Free Organisms | 2006 |
Role of FEF25%-75% as a predictor of bronchial hyperreactivity in allergic patients.
Topics: Adult; Biomarkers; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cross-Sectional Studies; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Male; Maximal Midexpiratory Flow Rate; Methacholine Chloride; ROC Curve | 2006 |
Cyclooxygenase-1 overexpression decreases Basal airway responsiveness but not allergic inflammation.
Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Humans; Hypersensitivity; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Transgenic; Ovalbumin; Plethysmography, Whole Body; Respiratory Function Tests; Reverse Transcriptase Polymerase Chain Reaction; Transgenes | 2006 |
Bronchial responsiveness to methacholine and adenosine 5'-monophosphate in atopic and non-atopic preschool children with recurrent wheezing.
Topics: Adenosine Monophosphate; Area Under Curve; Auscultation; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Case-Control Studies; Chi-Square Distribution; Child; Child, Preschool; Female; Humans; Hypersensitivity; Male; Methacholine Chloride; Recurrence; Respiratory Sounds | 2007 |
Deletion of secretory group V phospholipase A2 attenuates cell migration and airway hyperresponsiveness in immunosensitized mice.
Topics: Animals; Antibodies; Antigens; Cell Movement; Gene Expression Regulation, Enzymologic; Hypersensitivity; Methacholine Chloride; Mice; Mice, Knockout; Ovalbumin; Phospholipases A; Phospholipases A2; Respiratory Hypersensitivity; Up-Regulation | 2007 |
Factor analysis in the Genetics of Asthma International Network family study identifies five major quantitative asthma phenotypes.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchoconstrictor Agents; Child; Factor Analysis, Statistical; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Immunoglobulin E; Male; Methacholine Chloride; Phenotype; Respiratory Function Tests; Rhinitis; Severity of Illness Index; Skin Tests; Vital Capacity | 2008 |
Establishing the phenotype in novel acute and chronic murine models of allergic asthma.
Topics: Acute Disease; Administration, Inhalation; Allergens; Animals; Antibodies; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cell Count; Chronic Disease; Disease Models, Animal; Hypersensitivity; Immunoglobulin E; Immunoglobulin G; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Phenotype; Plethysmography, Whole Body; Pneumonia; Respiratory Function Tests | 2008 |
Frequency of atopy and allergic disorders among adults with Type 1 diabetes mellitus in the southern Marmara region of Turkey.
Topics: Adult; Asthma; Diabetes Mellitus, Type 1; Female; Humans; Hypersensitivity; Hypersensitivity, Immediate; Male; Methacholine Chloride; Respiratory Function Tests; Skin Tests; Surveys and Questionnaires; Turkey | 2008 |
Sensitizing effects of chronic exposure and acute inhalation of ovalbumin aerosol on pulmonary C fibers in rats.
Topics: Administration, Inhalation; Aerosols; Allergens; Animals; Blood Pressure; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Heart Rate; Hypersensitivity; Inflammation; Lung; Male; Methacholine Chloride; Nerve Fibers, Unmyelinated; Neurons, Afferent; Ovalbumin; Rats; Rats, Inbred BN | 2008 |
Role of mediators in allergic and nonallergic asthma in dogs with hyperreactive airways.
Topics: Airway Resistance; Animals; Asthma; Bronchial Provocation Tests; Chromones; Citrates; Citric Acid; Dogs; Guinea Pigs; Histamine; Hypersensitivity; Lung Compliance; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Respiratory Tract Diseases; Tissue Extracts | 1983 |
Bronchial responses to inhaled histamine and methacholine after influenza virus vaccination in monkeys.
Topics: Animals; Bronchi; Histamine; Hypersensitivity; Influenza A virus; Macaca; Methacholine Chloride; Methacholine Compounds; Vaccination | 1983 |
Ro 21-7634, a new antiallergic agent with potent oral activity.
Topics: Administration, Oral; Animals; Guinea Pigs; Histamine Antagonists; Hypersensitivity; Immunity, Maternally-Acquired; Male; Methacholine Chloride; Methacholine Compounds; Passive Cutaneous Anaphylaxis; Pyridines; Quinazolines; Rats; Rats, Inbred Strains; Serotonin Antagonists | 1981 |
Linkage of high-affinity IgE receptor gene with bronchial hyperreactivity, even in absence of atopy.
Topics: Adult; Alleles; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Chromosome Mapping; Chromosomes, Human, Pair 11; Female; Genes, Immunoglobulin; Genetic Linkage; Heterozygote; Humans; Hypersensitivity; Introns; Male; Methacholine Chloride; Microsatellite Repeats; Middle Aged; Mutation; Phenotype; Polymorphism, Genetic; Receptors, IgE | 1995 |
Maternal asthma and idiopathic preterm labor.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Case-Control Studies; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Medical History Taking; Methacholine Chloride; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications; Spirometry | 1995 |
Work-related late asthmatic response induced by latex allergy.
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Follow-Up Studies; Gloves, Surgical; Humans; Hypersensitivity; Hypersensitivity, Delayed; Immunoglobulin E; Latex; Male; Methacholine Chloride; Occupational Diseases; Peak Expiratory Flow Rate; Respiration; Skin Tests; Time Factors | 1995 |
Human eosinophil-granule major basic protein and synthetic polycations induce airway hyperresponsiveness in vivo dependent on bradykinin generation.
Topics: Amino Acid Sequence; Animals; Blood Proteins; Bradykinin; Bronchoconstriction; Dose-Response Relationship, Drug; Enzyme Activation; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Hypersensitivity; Inflammation Mediators; Kallikreins; Male; Methacholine Chloride; Molecular Sequence Data; Oligopeptides; Polyamines; Polyelectrolytes; Polylysine; Rats; Rats, Sprague-Dawley; Respiratory System; Ribonucleases | 1995 |
Chronic respiratory symptoms and airway responsiveness to methacholine are associated with eosinophilia in older men: the Normative Aging Study.
Topics: Adult; Aged; Aged, 80 and over; Aging; Bronchial Hyperreactivity; Bronchial Provocation Tests; Eosinophilia; Humans; Hypersensitivity; Longitudinal Studies; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Skin Tests | 1995 |
Clinical and functional characteristics of patients two years after being affected by the soybean asthma epidemic in Barcelona.
Topics: Asthma; Bronchial Provocation Tests; Case-Control Studies; Disease Outbreaks; Dust; Female; Follow-Up Studies; Glycine max; Humans; Hypersensitivity; Immunoglobulin E; Lung; Male; Methacholine Chloride; Middle Aged; Spain; Spirometry | 1994 |
Effective allergen avoidance at high altitude reduces allergen-induced bronchial hyperresponsiveness.
Topics: Allergens; Altitude; Analysis of Variance; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Cohort Studies; Dust; Environmental Monitoring; Epidemiological Monitoring; Exercise Test; Forced Expiratory Volume; Histamine; Humans; Hypersensitivity; Immunoglobulin E; Methacholine Chloride; Mites; Peak Expiratory Flow Rate; Primary Prevention; Recurrence; Residence Characteristics; Residential Facilities; Seasons; Skin Tests; Time Factors | 1994 |
Involvement of thromboxane A2 in propranolol-induced bronchoconstriction after allergic bronchoconstriction in guinea pigs.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Asthma; Bridged Bicyclo Compounds; Bronchial Provocation Tests; Constriction, Pathologic; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Guinea Pigs; Hypersensitivity; Inflammation; Injections, Intravenous; Male; Methacholine Chloride; Premedication; Propranolol; Receptors, Prostaglandin; Thromboxane A2; Time Factors | 1994 |
The effect of neonatal capsaicin on the development of bronchial hyperresponsiveness in allergic rabbits.
Topics: Animals; Animals, Newborn; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Electric Stimulation; Female; Histamine; Hypersensitivity; Male; Methacholine Chloride; Neuropeptides; Rabbits; Radioimmunoassay | 1993 |
A longitudinal evaluation of bronchial responsiveness to methacholine in children: role of baseline lung function, gender, and change in atopic status.
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Child; Cohort Studies; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Hypersensitivity; Logistic Models; Longitudinal Studies; Lung; Male; Maximal Midexpiratory Flow Rate; Methacholine Chloride; Multivariate Analysis; Sex Characteristics; Skin Tests; Vital Capacity | 1996 |
Antigen-induced generation of lyso-phospholipids in human airways.
Topics: Adult; Asthma; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Dinoprost; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypersensitivity; Lysophospholipids; Male; Methacholine Chloride; Prostaglandin D2; Reference Values; Rhinitis; Time Factors | 1996 |
Total serum IgE is associated with asthma independently of specific IgE levels. The Spanish Group of the European Study of Asthma.
Topics: Adult; Age Factors; Allergens; Animals; Animals, Domestic; Antibodies; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cohort Studies; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Fungi; Humans; Hypersensitivity; Immunoglobulin E; Male; Methacholine Chloride; Mites; Respiratory Sounds; Sex Factors; Smoking; Spain; Spirometry; Surveys and Questionnaires | 1996 |
Effects of inflammation and acute beta-agonist inhalation on beta 2-AR signaling in human airways.
Topics: Albuterol; Allergens; Bronchi; Bronchoalveolar Lavage Fluid; Cyclic AMP; Down-Regulation; Epithelium; Humans; Hypersensitivity; In Vitro Techniques; Methacholine Chloride; Pindolol; Receptors, Adrenergic, beta-2; Signal Transduction | 1996 |
BAL neutrophilia in asthmatic patients. A by-product of eosinophil recruitment?
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cell Count; Cell Movement; Cilia; Eosinophilia; Eosinophils; Epithelium; Female; Humans; Hypersensitivity; Leukocytosis; Lung; Male; Methacholine Chloride; Middle Aged; Neutrophil Activation; Neutrophils; Peroxidase | 1996 |
Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model.
Topics: Airway Resistance; Animals; Bronchoalveolar Lavage; Bronchoconstrictor Agents; CD28 Antigens; Cell Division; Disease Models, Animal; Flow Cytometry; Histocytochemistry; Hypersensitivity; Immunoglobulin E; Immunoglobulin G; Immunohistochemistry; Inflammation; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; T-Lymphocytes | 1996 |
Factors relating to the severity of symptoms at 5 yrs in children with severe wheeze in the first 2 yrs of life.
Topics: Acute Disease; Airway Resistance; Asthma; Bronchial Provocation Tests; Child, Preschool; Female; Follow-Up Studies; Hospitalization; Humans; Hypersensitivity; Male; Methacholine Chloride; Prospective Studies; Regression Analysis; Respiratory Sounds | 1997 |
Bronchial reactivity and dietary antioxidants.
Topics: Adult; Antioxidants; Asthma; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Cross-Sectional Studies; Diet; Diet Surveys; Energy Intake; Female; Humans; Hypersensitivity; Male; Methacholine Chloride; Minerals; Odds Ratio; Rural Population; Scotland; Skin Tests; Vitamins | 1997 |
Smoking and bronchial responsiveness in nonatopic and atopic young adults. Spanish Group of the European Study of Asthma.
Topics: Adult; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Female; Humans; Hypersensitivity; Immunoglobulin E; Male; Methacholine Chloride; Smoking | 1997 |
Lower airway responses to rhinovirus-Hanks in healthy subjects with and without allergy.
Topics: Humans; Hypersensitivity; Methacholine Chloride; Picornaviridae Infections; Respiratory System; Respiratory Tract Infections; Rhinovirus; Spirometry | 1997 |
Respiratory syncytial virus infection results in airway hyperresponsiveness and enhanced airway sensitization to allergen.
Topics: Allergens; Animals; Bronchoconstrictor Agents; Cytokines; Eosinophils; Female; Humans; Hypersensitivity; Inflammation; Interferon-gamma; Interleukin-4; Interleukin-5; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Th2 Cells; Time Factors; Tumor Cells, Cultured | 1997 |
Seasonal variation in serum eosinophilic cationic protein (S-ECP) in a general population sample.
Topics: Adult; Blood Proteins; Bronchial Provocation Tests; Bronchodilator Agents; Eosinophil Granule Proteins; Humans; Hypersensitivity; Inflammation Mediators; Methacholine Chloride; Middle Aged; Pollen; Ribonucleases; Seasons; Skin Tests | 1997 |
Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography.
Topics: Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Disease Models, Animal; Female; Humans; Hypersensitivity; Methacholine Chloride; Mice; Mice, Inbred BALB C; Plethysmography, Whole Body; Reproducibility of Results | 1997 |
Role of cytosolic phospholipase A2 in allergic response and parturition.
Topics: Anaphylaxis; Animals; Bronchial Hyperreactivity; Chimera; Cloning, Molecular; Cytosol; Eicosanoids; Female; Gene Targeting; Hypersensitivity; Labor, Obstetric; Macrophages, Peritoneal; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pregnancy | 1997 |
Persistence of atopic effects on airway calibre and bronchial responsiveness in older adults.
Topics: Age Factors; Aged; Bronchial Hyperreactivity; Eosinophils; Forced Expiratory Volume; Humans; Hypersensitivity; Immunoglobulin G; Leukocyte Count; Methacholine Chloride; Middle Aged; Smoking | 1997 |
Repeated measurements of airway and parenchymal mechanics in rats by using low-frequency oscillations.
Topics: Aerosols; Airway Resistance; Animals; Disease Models, Animal; Hypersensitivity; Lung; Male; Methacholine Chloride; Rats; Respiratory Mechanics; Thorax | 1998 |
Atopy in cough sensitivity to capsaicin and bronchial responsiveness in young females.
Topics: Adult; Allergens; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Capsaicin; Cough; Cross-Sectional Studies; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Immunoglobulin E; Methacholine Chloride; Odds Ratio; Sex Characteristics | 1998 |
Activation of B-lymphocytes during pollen season. Effect of immunotherapy.
Topics: Adult; Allergens; Antigens, CD19; Asthma; B-Lymphocytes; CD40 Antigens; Cell Count; Double-Blind Method; Female; Flow Cytometry; HLA-DR Antigens; Humans; Hypersensitivity; Immunotherapy; Lymphocyte Activation; Male; Methacholine Chloride; Middle Aged; Pollen; Receptors, IgE; Seasons; Trees | 1998 |
Effects of S-salbutamol on human isolated bronchus.
Topics: Adenosine; Albuterol; Bradykinin; Bronchi; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Histamine; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene C4; Methacholine Chloride; Platelet Activating Factor | 1998 |
Differential effects of endogenous and exogenous interferon-gamma on immunoglobulin E, cellular infiltration, and airway responsiveness in a murine model of allergic asthma.
Topics: Administration, Inhalation; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Hypersensitivity; Immunoglobulin E; Injections, Intraperitoneal; Interferon-gamma; Leukocytes; Lymph Nodes; Macrophages, Alveolar; Methacholine Chloride; Mice; Mice, Knockout; Ovalbumin; Spleen; T-Lymphocytes | 1998 |
In vivo function of an interleukin 2 receptor beta chain (IL-2Rbeta)/IL-4Ralpha cytokine receptor chimera potentiates allergic airway disease.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Flow Cytometry; Humans; Hypersensitivity; Immunization; Immunoglobulin E; Immunoglobulin G; Methacholine Chloride; Mice; Mice, Transgenic; Ovalbumin; Receptors, Interleukin-2; Receptors, Interleukin-4; Recombinant Fusion Proteins; Signal Transduction; STAT6 Transcription Factor; T-Lymphocytes; Th2 Cells; Trans-Activators | 1998 |
Individual allergens as risk factors for bronchial responsiveness in young adults.
Topics: Adult; Age Factors; Allergens; Animals; Antigens; Antigens, Fungal; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cats; Cladosporium; Dust; Female; Humans; Hypersensitivity; Immunoglobulin E; Male; Methacholine Chloride; Mites; Poaceae; Pollen; Risk Factors; Skin Tests; Smoking; Trees | 1998 |
Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Eosinophils; Histocytochemistry; Hypersensitivity; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, SCID; Mice, Transgenic; Ovalbumin; Th1 Cells; Th2 Cells | 1999 |
Blood eosinophils from asymptomatic allergics have a reduced capacity to produce oxygen-free radicals.
Topics: Acridines; Adult; Blood Cells; Bronchoconstrictor Agents; Eosinophils; Female; Humans; Hypersensitivity; Leukocyte Count; Luminescent Measurements; Luminol; Male; Methacholine Chloride; Middle Aged; Pain Measurement; Pollen; Reactive Oxygen Species; Rhinitis, Allergic, Seasonal; Stimulation, Chemical; Trees | 1998 |
Vascularity in asthmatic airways: relation to inhaled steroid dose.
Topics: Administration, Inhalation; Adult; Asthma; Basement Membrane; Beclomethasone; Bronchi; Bronchoconstrictor Agents; Bronchoscopy; Case-Control Studies; Collagen; Drug Administration Schedule; Female; Glucocorticoids; Humans; Hypersensitivity; Immunohistochemistry; Male; Methacholine Chloride; Middle Aged; Neovascularization, Pathologic | 1999 |
Shifts in lung lymphocyte profiles correlate with the sequential development of acute allergic and chronic tolerant stages in a murine asthma model.
Topics: Airway Resistance; Animals; Asthma; B-Lymphocytes; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fluorescent Antibody Technique; Hypersensitivity; Immunoglobulin E; Lymphocytes; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Ovalbumin; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes; Time Factors | 1999 |
Vernal keratoconjunctivitis in a Stockholm ophthalmic centre--epidemiological, functional, and immunologic investigations.
Topics: Adolescent; Africa; Asia; Asthma; Biomarkers; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Child; Child, Preschool; Chlamydia; Ethnicity; Female; Humans; Hypersensitivity; Keratoconjunctivitis; Male; Methacholine Chloride; Retrospective Studies; Seasons; Sweden | 1999 |
Increased eosinophil cation protein level in sensitized nonasthmatics is linked to subsequent hyperresponsiveness to methacholine. The Odense Schoolchild Study.
Topics: Adolescent; Adult; Allergens; Asthma; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Hypersensitivity; Immunoglobulin E; Leukocyte Count; Male; Methacholine Chloride; Prospective Studies; Ribonucleases; Skin Tests; Surveys and Questionnaires | 2000 |
Atopy and pulmonary function abnormalities in children with a history of acute bronchiolitis.
Topics: Acute Disease; Bronchial Provocation Tests; Bronchiolitis; Bronchoconstrictor Agents; Child; Female; Forced Expiratory Volume; Humans; Hypersensitivity; Incidence; Lung; Male; Maximal Midexpiratory Flow Rate; Medical Records; Methacholine Chloride; Peak Expiratory Flow Rate; Reference Values; Spirometry; Vital Capacity | 2000 |
IL-10 reduces Th2 cytokine production and eosinophilia but augments airway reactivity in allergic mice.
Topics: Animals; Bronchial Hyperreactivity; Bronchitis; Bronchoalveolar Lavage Fluid; Cytokines; Dose-Response Relationship, Drug; Eosinophilia; Female; Hypersensitivity; Interleukin-10; Methacholine Chloride; Mice; Mice, Inbred BALB C; Pollen; Th2 Cells; Trachea | 2000 |
Differential effects of nitric oxide synthase inhibitors in an in vivo allergic rat model.
Topics: Animals; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypersensitivity; Male; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thiourea | 2000 |
Cyclooxygenase inhibition increases interleukin 5 and interleukin 13 production and airway hyperresponsiveness in allergic mice.
Topics: Animals; Arachidonic Acid; Chemokines, CC; Cyclooxygenase Inhibitors; Female; Hypersensitivity; Immunoglobulin E; Indomethacin; Interleukin-13; Interleukin-4; Interleukin-5; Interleukin-6; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Respiratory Hypersensitivity; Specific Pathogen-Free Organisms | 2000 |
Tidal midexpiratory flow as a measure of airway hyperresponsiveness in allergic mice.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Allergens; Animals; Bronchial Hyperreactivity; Bronchitis; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytokines; Female; Hypersensitivity; Immunoglobulins; Lung Compliance; Maximal Midexpiratory Flow Rate; Methacholine Chloride; Mice; Mice, Inbred BALB C; Plethysmography; Pulmonary Gas Exchange; Respiration; Tidal Volume; Time Factors | 2001 |
Atopic status and level of bronchial responsiveness in parents of children with acute bronchiolitis.
Topics: Acute Disease; Adult; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchiolitis; Bronchoconstrictor Agents; Child, Preschool; Female; Forced Expiratory Volume; Genetic Predisposition to Disease; Humans; Hypersensitivity; Immunoglobulin E; Infant; Male; Methacholine Chloride; Parents; Reference Values; Skin Tests | 2000 |
Bronchoconstrictor reactivity to NKA in allergic dogs: a comparison to histamine and methacholine.
Topics: Administration, Inhalation; Aerosols; Animals; Bronchial Hyperreactivity; Bronchial Spasm; Bronchoconstriction; Dogs; Female; Histamine; Hypersensitivity; Male; Methacholine Chloride; Neurokinin A | 2001 |
Immune interaction between respiratory syncytial virus infection and allergen sensitization critically depends on timing of challenges.
Topics: Allergens; Animals; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Female; Hypersensitivity; Interferon-gamma; Interleukin-13; Lung; Lymphocyte Count; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Pulmonary Eosinophilia; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Time Factors; Virus Replication; Weight Loss | 2001 |
Airway responsiveness to inhaled acetaldehyde in subjects with allergic rhinitis: relationship to methacholine responsiveness.
Topics: Acetaldehyde; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Female; Humans; Hypersensitivity; Male; Methacholine Chloride; Rhinitis; Spirometry | 2002 |
Mechanism of nasal secretion mediated via nerve reflex in guinea pigs and evaluation of antiallergic drugs.
Topics: Allergens; Aminopyridines; Animals; Atropine Derivatives; Bronchodilator Agents; Capsaicin; Ganglionic Blockers; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Histamine; Hypersensitivity; Lidocaine; Methacholine Chloride; Nasal Mucosa; ortho-Aminobenzoates; Parasympatholytics; Phthalazines; Pyrilamine; Reflex | 1992 |
Risk factors for increased airway responsiveness to methacholine challenge among laboratory animal workers.
Topics: Adolescent; Adult; Animals; Animals, Laboratory; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Humans; Hypersensitivity; Male; Medical Laboratory Personnel; Methacholine Chloride; Middle Aged; Occupational Diseases; Risk Factors; Skin Tests | 1992 |
Atopy, bronchial responsiveness, and symptoms in wheezy 3 year olds.
Topics: Blood Gas Monitoring, Transcutaneous; Bronchial Provocation Tests; Child, Preschool; Cohort Studies; Female; Humans; Hypersensitivity; Male; Methacholine Chloride; Respiratory Sounds | 1992 |
Elevated soluble interleukin-2 receptors in young healthy cigarette smokers: lack of association with atopy or airways hyperresponsiveness.
Topics: Humans; Hypersensitivity; Methacholine Chloride; Receptors, Interleukin-2; Respiratory Hypersensitivity; Skin Tests; Smoking | 1992 |
Anesthetic effects on pulmonary allergic responses in rats: changes in sensitivity to serotonin.
Topics: Airway Resistance; Anesthetics; Animals; Antigens; Histamine; Hypersensitivity; Lung; Male; Mast Cells; Methacholine Chloride; Rats; Rats, Inbred Strains; Serotonin | 1992 |
Relationships of haptoglobin level to FEV1, wheezing, bronchial hyper-responsiveness and allergy.
Topics: Adult; alpha 1-Antitrypsin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Comorbidity; Forced Expiratory Volume; Haptoglobins; Humans; Hypersensitivity; Male; Methacholine Chloride; Middle Aged; Orosomucoid; Respiratory Sounds; Smoking | 1991 |
Effect of epithelial denudation, inflammatory mediators and mast cell activation on the sensitivity of isolated human airways to methacholine.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Aged, 80 and over; Antibodies, Anti-Idiotypic; Dinoprost; Epithelium; Histamine; Humans; Hypersensitivity; Immunoglobulin E; In Vitro Techniques; Inflammation; Kinetics; Lung; Male; Mast Cells; Methacholine Chloride; Middle Aged; Muscle Contraction; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; SRS-A | 1991 |
Persistence of increased nonspecific bronchial reactivity in allergic children and adolescents.
Topics: Adolescent; Adult; Airway Resistance; Bronchi; Bronchial Provocation Tests; Child; Humans; Hypersensitivity; Longitudinal Studies; Methacholine Chloride; Methacholine Compounds; Skin Tests | 1990 |
Elevated mononuclear leukocyte phosphodiesterase in allergic dogs with and without airway hyperresponsiveness.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bronchial Provocation Tests; Dogs; Female; Hypersensitivity; Leukocytes; Male; Methacholine Chloride; Methacholine Compounds; Monocytes; Respiratory Hypersensitivity; Skin Tests | 1987 |
Cat- or dog-induced immediate and late asthmatic responses before and after immunotherapy.
Topics: Adult; Allergens; Animals; Bronchial Provocation Tests; Cats; Dogs; Humans; Hypersensitivity; Immunotherapy; Methacholine Chloride; Methacholine Compounds; Skin Tests | 1988 |
Comparison of nasal responsiveness to histamine, methacholine and phentolamine in allergic rhinitis patients and controls.
Topics: Adult; Airway Resistance; Animals; Female; Histamine; Humans; Hypersensitivity; Male; Methacholine Chloride; Methacholine Compounds; Mites; Nasal Provocation Tests; Phentolamine; Radioallergosorbent Test; Skin Tests | 1987 |
Airway responses to aerosolized methacholine and citric acid in ponies with recurrent airway obstruction (heaves).
Topics: Aerosols; Airway Obstruction; Airway Resistance; Animals; Citrates; Citric Acid; Female; Histamine; Horse Diseases; Horses; Housing, Animal; Hypersensitivity; Lung Compliance; Male; Methacholine Chloride; Methacholine Compounds | 1986 |
Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with methacholine bronchial hyperresponsiveness.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; Hypersensitivity; Methacholine Chloride; Methacholine Compounds; Middle Aged; Pulmonary Alveoli; Rhinitis; Therapeutic Irrigation | 1987 |