Page last updated: 2024-08-17

methacholine chloride and Bronchial Spasm

methacholine chloride has been researched along with Bronchial Spasm in 110 studies

Research

Studies (110)

Timeframe	Studies, this research(%)	All Research%
pre-1990	61 (55.45)	18.7374
1990's	31 (28.18)	18.2507
2000's	12 (10.91)	29.6817
2010's	4 (3.64)	24.3611
2020's	2 (1.82)	2.80

Authors

Authors	Studies
Deragon, A; Dubrovsky, AS; Gagnon, F; Lands, LC; Marzook, N; Rampakakis, E; Shapiro, AJ; Zielinski, D	1
Bowser, JE; Byars, P; Byrne, R; Hunter, CL; Moore, JW; Swiderski, CE; Wills, RW; Wilson, RM	1
Brégeon, F; Bues-Charbit, M; Cabon, E; Charpin, D; Del Volgo, MJ; Delliaux, S; Rey, F; Tissier-Ducamp, D	1
Cook, JM; Emala, CW; Fu, XW; Gallos, G; Harrison, N; Perez-Zoghbi, J; Poe, MM; Siviski, ME; Yim, PD; Yocum, GT	1
Ford, AP; Undem, BJ; Weigand, LA	1
Baronio, R; Bindi, E; Corradi, M; Paggiaro, P; Petruzzelli, S; Singh, D	1
Clerbaux, T; De Kock, M; Detry, B; Gianello, P; Jolliet, P; Liistro, G; Reynaert, M; Roeseler, J; Veriter, C; Watremez, C	1
Clerbaux, T; deKock, M; Detry, B; Gianello, P; Jolliet, P; Liistro, G; Reynaert, M; Roeseler, J; Watremez, C	1
Newhouse, MT; Parry-Billings, M; Patel, P	1
Miro, AM; Pinsky, MR; Rogers, PL	1
Brown, LL; Martin, BL; Morris, MJ	1
Barnes, PJ; Erin, EM; Hansel, TT; Maus, JG; Neighbour, H; Tan, AJ; Tennant, RC	1
Groeben, H; Peters, J	1
Buchman, TG; Girling, LG; Graham, MR; McManus, BM; Mutch, WA; Walker, EK	1
FREESE, HB; HAMBOURGER, WE	1
BEAKEY, JF; SEGAL, MS	1
Edholm, LE; Mattila, MJ; Salonen, RO	1
Boushey, HA; Epstein, J; Holtzman, MJ; Nadel, JA; Sheppard, D	1
Robbins, JJ	1
Banner, AS; Chausow, AM	1
Mink, SN	1
Cartier, A; Malo, JL; Martin, RR; Pineau, L; Sestier, M	1
Birch, S; Chadha, TS; Jenouri, G; Sackner, MA; Schneider, AW	1
Enns, EG; Logus, JW; Man, SF; Trajan, M	1
Frazier, DT; Lee, LY; Yu, LK	1
Murlas, C; Roum, JH	1
Conaty, JM; Townshend-Piala, P; Williams, JC	1
Solway, J	1
Bélanger, J; Cormier, Y; Côté, A	1
Biggs, DF; Jafarian, A; Kreutz, FT; Suresh, MR	1
Atton, L; Cormier, Y; Coté, MC; Laberge, F; Laviolette, M; Sériès, F	1
Boulet, LP; Cournoyer, I; Deschesnes, F; Freeston, MH; Nouwen, A	1
Bartter, TC; Dubois, J; Pratter, MR	1
Cugell, DW; Grammer, LC; Harris, KE; Patterson, R	1
Bloch, KJ; Cockrill, BA; Johnson, DC; Kacmarek, RM; Ripple, R; Zapol, WM	1
Iga, T; Ohtani, H; Sawada, Y; Yamamoto, K	1
Broadley, KJ; Lewis, CA	1
Gowski, DT; Hoffman, LA; Lutz, J; Miro, AM; Pinsky, MR; Sigler, DW; Tasota, FJ; Zullo, T	1
Anticoli, S; Graziani, E; Mannino, F; Terzano, C	1
Bonfante, G; Heller, MB; Melanson, SW	1
Chabat, F; Gückel, C; Hansell, DM; Taylor, DA; Wells, AU	1
Homma, T; Irvin, CG	1
Banfi, P; Bossi, R; Braga, PC; Castelli, C; Filipazzi, V	1
Irvin, CG; Wagers, SS	1
Celly, C; Chapman, RW; House, A; Kreutner, W; Young, S	1
Buescher, H; Fozard, JR	1
Choi, S; Koh, YI	1
Bates, JH; Irvin, CG; Tomioka, S	1
Bishop, MJ; Hildebrandt, J; Isner, PD; Pierson, DJ; Wu, SC	1
Chande, VT; Skoner, DP	1
De Vos, C	1
Cocco, G; Masi, C; Melillo, E; Melillo, G; Padovano, A	1
Arm, JP; Charlesson, S; Chee, P; Christie, PE; Ford-Hutchinson, AW; Lee, TH; Tagari, P	1
Sen, RP; Walsh, TE	1
Bruderman, I; Cohen, R; Schachter, J	1
Baldwin, JC; Glanville, AR; Robin, ED; Theodore, J	1
Baldi, S; Bucca, C; Caria, E; Rolla, G; Scappaticci, E	1
Finnerty, JP; Holgate, ST; Phillips, GD	1
Hjemdahl, P; Larsson, K; Theodorsson, E	1
Ciaccia, A; Fabbri, LM; La Corte, R; Papi, A; Potena, A; Trotta, F	1
Cormier, Y; Lecours, R; Legris, C	1
Cartier, A; L'Archevêque, J; Malo, JL	2
Holgate, ST; Lau, LC; Polosa, R	1
Beasley, R; Burgess, C; Crane, J; Windom, H	1
Austin, DR; Hanifin, JM; Hirshman, CA; Hulbert, W; Klein, W	1
Chamberlain, DW; Cooper, JD; Grossman, RF; Maurer, JR; McLean, PA; Zamel, N	1
Coutts, C; Higenbottam, T; Jackson, M; Rashdi, T; Stewart, S; Wallwork, J	1
Camner, P; Philipson, K; Svartengren, M	1
Arm, JP; Lee, TH; O'Hickey, SP; Rees, PJ	1
Engel, LA; Paré, PD; Wheatley, JR	1
Popp, W; Rauscher, H; Ritschka, L	1
Chalaoui, J; Ghezzo, H; Malo, J; Malo, JL; Pison, C; Rouleau, JL	1
Gabb, GM; Glanville, AR; Robin, ED; Theodore, J	1
Braun, SR; Khadra, I; Scott, GC	1
De Gasperi, M; Ferrari, M; Lechi, A; Olivieri, M	1
Barnes, PJ; Chung, KF; Lammers, JW; McCusker, M; Nichol, GM; Roberts, NM	1
Marthan, R; Woolcock, AJ	1
Aurich, R; Harrison, PJ; Holgate, ST; Rafferty, P	1
Bryant, DH	1
Brancatisano, M; Brusasco, V; Crimi, E; Crimi, P; Losurdo, E	1
Hoffarth, HP; Reier, W; Ulmer, WT; von Donat, J	1
Bigby, BG; Boushey, HA; Myers, DJ	1
Reshef, A; Saaid, M; Weiner, P	1
Irwin, RS; Pratter, MR	1
Ahrens, R; Harman, E; Hendeles, L; Hill, M; Massey, KL; Rutledge, DR	1
Barnes, PJ; Chung, KF; McCusker, M; Minette, P	1
James, AL; Paré, PD	1
Hida, W; Horio, S; Inoue, H; Lin, YN; Nogami, H; Okayama, M; Takishima, T; Yafuso, N	1
Druz, WS; Jenne, JW; Manfredi, CJ; Shaughnessy, TK; Vestal, RE	1
Ishii, M; Sasaki, J; Suzuki, S; Takishima, T	1
Camner, P; Linnman, L; Philipson, K; Svartengren, M	1
Greenspon, LW; Morrissey, WL	1
Bernstein, PR; Kern, R; Krell, RD; Patterson, R; Smith, LJ	1
Olgiati, R; Wanner, A	1
Lloyd, DA; McCourtie, DR; Moote, DW; Wells, GA	1
Maesen, F; Smeets, J; Tjwa, MK	1
England, SJ; Ho, V; Zamel, N	1
Bai, TR; Martin, JG; Shore, SA; Wang, CG	1
Downes, H; Hirshman, CA	2
Casthely, PA; Cottrell, JE; Urquhart, PA	1
Sasaki, H; Sekizawa, K; Takishima, T	1
Graff-Lonnevig, V; Hedlin, G	1
Baltes, E; Maesen, FP; Rihoux, JP; Smeets, JJ	1
Cockcroft, DW	1
Bewtra, A; Hopp, RJ; Nair, NM; Townley, RG	1
Adams, GK; Kleeberger, SR; Spannhake, EW; Wagner, EM	1
Muñoz-López, F	1
Cherniack, NS; Deal, EC; Kelsen, SG; Oliven, A	1

Reviews

4 review(s) available for methacholine chloride and Bronchial Spasm

Article	Year
The pharmacology of aerosolized airway challenge. Respiratory care clinics of North America, 1999, Volume: 5, Issue:4 Topics: Administration, Inhalation; Aerosols; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchial Spasm; Bronchoconstriction; Bronchoconstrictor Agents; Histamine; Humans; Methacholine Chloride	1999
Antihistamines and allergic asthma. Allergie et immunologie, 1991, Volume: 23, Issue:9 Topics: Asthma; Bronchial Spasm; Histamine H1 Antagonists; Humans; Methacholine Chloride; Physical Exertion; Receptors, Histamine H2	1991
Anti-cholinergic agents and their use in asthma. Progress in clinical and biological research, 1988, Volume: 263 Topics: Allergens; Asthma; Atropine Derivatives; Bronchial Provocation Tests; Bronchial Spasm; Histamine; Humans; Ipratropium; Methacholine Chloride; Methacholine Compounds; Parasympatholytics; Physical Exertion	1988
Bronchial inhalation tests. I. Measurement of nonallergic bronchial responsiveness. Annals of allergy, 1985, Volume: 55, Issue:4 Topics: Administration, Intranasal; Aerosols; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Dose-Response Relationship, Drug; Histamine; Humans; Methacholine Chloride; Methacholine Compounds; Occupational Diseases	1985

Trials

26 trial(s) available for methacholine chloride and Bronchial Spasm

Article	Year
Relief of methacholine-induced bronchospasm with extrafine beclomethasone dipropionate/formoterol in comparison with salbutamol in asthma. Pulmonary pharmacology & therapeutics, 2012, Volume: 25, Issue:5 Topics: Adult; Albuterol; Asthma; Beclomethasone; Bronchial Spasm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Ethanolamines; Female; Forced Expiratory Volume; Formoterol Fumarate; Humans; Male; Methacholine Chloride; Middle Aged	2012
Protection against methacholine-induced bronchospasm: salbutamol pMDI versus Clickhaler DPI. The European respiratory journal, 2003, Volume: 21, Issue:5 Topics: Adolescent; Adult; Albuterol; Bronchial Provocation Tests; Bronchial Spasm; Bronchoconstrictor Agents; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Metered Dose Inhalers; Methacholine Chloride; Middle Aged; Powders	2003
Glycopyrrolate causes prolonged bronchoprotection and bronchodilatation in patients with asthma. Chest, 2005, Volume: 128, Issue:4 Topics: Asthma; Bronchial Spasm; Bronchoconstrictor Agents; Cholinergic Agents; Cross-Over Studies; Double-Blind Method; Glycopyrrolate; Humans; Methacholine Chloride; Placebos	2005
Lidocaine exerts its effect on induced bronchospasm by mitigating reflexes, rather than by attenuation of smooth muscle contraction. Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:3 Topics: Adult; Airway Resistance; Anesthetics, Local; Bronchial Provocation Tests; Bronchial Spasm; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Lidocaine; Male; Methacholine Chloride; Muscle, Smooth; Nebulizers and Vaporizers; Propiophenones; Reflex	2007
Effect of route of atropine delivery on bronchospasm from cold air and methacholine. Journal of applied physiology: respiratory, environmental and exercise physiology, 1983, Volume: 54, Issue:1 Topics: Adult; Air; Atropine; Bronchial Spasm; Cold Temperature; Differential Threshold; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds	1983
Nebulized glucagon in the treatment of bronchospasm in asthmatic patients. The American journal of emergency medicine, 1998, Volume: 16, Issue:3 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Bronchial Spasm; Bronchoconstrictor Agents; Bronchospirometry; Child; Cross-Over Studies; Double-Blind Method; Female; Glucagon; Humans; Male; Methacholine Chloride; Time Factors; Treatment Outcome	1998
Mechanism of mosaic attenuation of the lungs on computed tomography in induced bronchospasm. Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 86, Issue:2 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchoconstrictor Agents; Female; Forced Expiratory Volume; Humans; Hypoxia; Lung; Male; Methacholine Chloride; Oxygen Consumption; Tomography, X-Ray Computed; Vasoconstriction	1999
Levodropropizine (LD) activity in allergic asthmatic patients, challenged with ultrasonically nebulized distilled water, metacholine and allergen-induced bronchospasm. Clinical trials and meta-analysis, 1994, Volume: 29, Issue:1 Topics: Administration, Oral; Adolescent; Adult; Allergens; Antitussive Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchial Spasm; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypersensitivity; Male; Methacholine Chloride; Middle Aged; Nebulizers and Vaporizers; Placebos; Propylene Glycols; Ultrasonic Therapy; Water	1994
A trial of nebulized magnesium sulfate to reverse bronchospasm in asthmatic patients. Annals of emergency medicine, 1992, Volume: 21, Issue:9 Topics: Adult; Asthma; Bronchial Spasm; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Magnesium Sulfate; Male; Methacholine Chloride; Nebulizers and Vaporizers	1992
Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects. The American review of respiratory disease, 1991, Volume: 143, Issue:5 Pt 1 Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Male; Methacholine Chloride; Middle Aged; SRS-A	1991
Comparative protective effect of the inhaled beta 2-agonist salbutamol (albuterol) on bronchoconstriction provoked by histamine, methacholine, and adenosine 5'-monophosphate in asthma. The Journal of allergy and clinical immunology, 1990, Volume: 85, Issue:4 Topics: Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adult; Aerosols; Albuterol; Asthma; Bronchial Spasm; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Histamine; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged	1990
Inhibition of adenosine 5'-monophosphate- and methacholine-induced bronchoconstriction in asthma by inhaled frusemide. The European respiratory journal, 1990, Volume: 3, Issue:6 Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Double-Blind Method; Female; Forced Expiratory Volume; Furosemide; Humans; Male; Methacholine Chloride; Methacholine Compounds; Randomized Controlled Trials as Topic	1990
The airways effects of inhaled chlorbutol in asthmatic subjects. The European respiratory journal, 1990, Volume: 3, Issue:6 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chlorobutanol; Double-Blind Method; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Nebulizers and Vaporizers; Terbutaline	1990
Airway responsiveness to methacholine after inhalation of nebulized hypertonic saline in bronchial asthma. The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:2 Pt 1 Topics: Administration, Inhalation; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Muscle, Smooth; Nebulizers and Vaporizers; Saline Solution, Hypertonic; Sodium Chloride	1989
Transdermal scopolamine attenuates methacholine-induced bronchospasm. The Journal of allergy and clinical immunology, 1989, Volume: 84, Issue:1 Topics: Administration, Cutaneous; Adult; Bronchial Spasm; Humans; Male; Methacholine Chloride; Methacholine Compounds; Scopolamine	1989
Differential effects of nifedipine and diltiazem on methacholine-induced bronchospasm in allergic asthma. Annals of allergy, 1989, Volume: 63, Issue:3 Topics: Adult; Asthma; Blood Pressure; Bronchial Provocation Tests; Bronchial Spasm; Clinical Trials as Topic; Diltiazem; Female; Forced Expiratory Volume; Heart Rate; Humans; Male; Methacholine Chloride; Methacholine Compounds; Nifedipine; Placebos; Random Allocation	1989
Effect of theophylline on airway responses to inhaled platelet-activating factor in man. The European respiratory journal, 1989, Volume: 2, Issue:8 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Double-Blind Method; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor; Randomized Controlled Trials as Topic; Theophylline	1989
Is a myogenic response involved in deep inspiration-induced bronchoconstriction in asthmatics? The American review of respiratory disease, 1989, Volume: 140, Issue:5 Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Humans; Methacholine Chloride; Methacholine Compounds; Muscle, Smooth; Nifedipine; Respiration; Trachea	1989
The in vivo potency and selectivity of azelastine as an H1 histamine-receptor antagonist in human airways and skin. The Journal of allergy and clinical immunology, 1988, Volume: 82, Issue:6 Topics: Administration, Inhalation; Adult; Bronchial Spasm; Dose-Response Relationship, Immunologic; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Methacholine Chloride; Methacholine Compounds; Middle Aged; Phthalazines; Pyridazines; Skin Tests	1988
The inhibition of sulfur dioxide-induced bronchoconstriction in asthmatic subjects by cromolyn is dose dependent. The American review of respiratory disease, 1986, Volume: 133, Issue:6 Topics: Adult; Airway Resistance; Asthma; Bronchial Spasm; Cromolyn Sodium; Dose-Response Relationship, Drug; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Osmolar Concentration; Sulfur Dioxide	1986
Isotonic nebulized disodium cromoglycate provides better protection against methacholine- and exercise-induced bronchoconstriction. The American review of respiratory disease, 1988, Volume: 137, Issue:6 Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchial Spasm; Cromolyn Sodium; Forced Expiratory Volume; Humans; Hypotonic Solutions; Isotonic Solutions; Methacholine Chloride; Methacholine Compounds; Nebulizers and Vaporizers	1988
Dose response of inhaled gallopamil (D600), a calcium channel blocker, in attenuating airway reactivity to methacholine and exercise. The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:5 Pt 1 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Female; Forced Expiratory Volume; Gallopamil; Humans; Male; Methacholine Chloride; Methacholine Compounds; Random Allocation	1988
Ketotifen inhibits the cutaneous but not the airway responses to platelet-activating factor in man. The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:6 Topics: Adult; Aerosols; Blood Cell Count; Bronchial Provocation Tests; Bronchial Spasm; Double-Blind Method; Humans; Ketotifen; Male; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor; Random Allocation; Skin Tests	1988
Ketotifen and methacholine-induced bronchospasm. Allergy, 1986, Volume: 41, Issue:8 Topics: Adolescent; Adult; Bronchial Spasm; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Ketotifen; Male; Methacholine Chloride; Methacholine Compounds; Peak Expiratory Flow Rate	1986
The effect of ketotifen on bronchial hyperreactivity in childhood asthma. The Journal of allergy and clinical immunology, 1985, Volume: 76, Issue:1 Topics: Adolescent; Asthma; Bronchial Spasm; Child; Female; Humans; Ketotifen; Male; Methacholine Chloride; Methacholine Compounds	1985
Protective effect by UCB JO28 against histamine and methacholine induced bronchial hyperreactivity. European journal of clinical pharmacology, 1985, Volume: 28, Issue:5 Topics: Adolescent; Adult; Asthma; Bronchial Spasm; Clinical Trials as Topic; Female; Histamine; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Piperidines; Prospective Studies	1985

Other Studies

80 other study(ies) available for methacholine chloride and Bronchial Spasm

Article	Year
Characterizing pediatric lung ultrasound findings during a chemically induced bronchospasm. Pediatric pulmonology, 2022, Volume: 57, Issue:6 Topics: Adolescent; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Agents; Child; Humans; Lung; Methacholine Chloride; Pediatrics; Ultrasonography	2022
Airway Hyperresponsiveness Is Severe and Persistent in an Equine Model of Neutrophilic Asthma. American journal of respiratory cell and molecular biology, 2020, Volume: 62, Issue:6 Topics: Airway Remodeling; Animals; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Disease Models, Animal; Horse Diseases; Horses; Humans; Methacholine Chloride; Neutrophils; Respiratory Hypersensitivity; Species Specificity	2020
[Occurrence of delayed symptoms after a challenge test with methacholine]. Revue des maladies respiratoires, 2018, Volume: 35, Issue:3 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchial Spasm; Delayed Diagnosis; Female; Humans; Longitudinal Studies; Male; Methacholine Chloride; Middle Aged; Prevalence; Time Factors	2018
Selective targeting of the α5-subunit of GABAA receptors relaxes airway smooth muscle and inhibits cellular calcium handling. American journal of physiology. Lung cellular and molecular physiology, 2015, May-01, Volume: 308, Issue:9 Topics: Animals; Bradykinin; Bronchial Spasm; Bronchoconstriction; Bronchodilator Agents; Calcium; Cells, Cultured; Diazepam; GABA-A Receptor Agonists; Guinea Pigs; Humans; Imidazoles; Ion Channel Gating; Male; Methacholine Chloride; Muscle, Smooth; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Receptors, GABA-A; Respiratory System	2015
A role for ATP in bronchoconstriction-induced activation of guinea pig vagal intrapulmonary C-fibres. The Journal of physiology, 2012, Aug-15, Volume: 590, Issue:16 Topics: Action Potentials; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Animals; Apyrase; Bronchial Spasm; Guinea Pigs; Histamine; Male; Methacholine Chloride; Nodose Ganglion; Purinergic P2X Receptor Antagonists; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2X; Reverse Transcriptase Polymerase Chain Reaction; Tissue Culture Techniques; Vagus Nerve	2012
An improved porcine model of stable methacholine-induced bronchospasm. Intensive care medicine, 2003, Volume: 29, Issue:1 Topics: Animals; Asthma; Bronchial Spasm; Disease Models, Animal; Methacholine Chloride; Reproducibility of Results; Respiration, Artificial; Respiratory Mechanics; Swine; Ventilation-Perfusion Ratio	2003
Effects of helium-oxygen on respiratory mechanics, gas exchange, and ventilation-perfusion relationships in a porcine model of stable methacholine-induced bronchospasm. Intensive care medicine, 2003, Volume: 29, Issue:9 Topics: Acute Disease; Animals; Asthma; Bronchial Spasm; Bronchoconstrictor Agents; Disease Models, Animal; Helium; Methacholine Chloride; Oxygen Inhalation Therapy; Pulmonary Gas Exchange; Respiration, Artificial; Respiratory Mechanics; Swine; Treatment Outcome; Ventilation-Perfusion Ratio	2003
Effects of the components of positive airway pressure on work of breathing during bronchospasm. Critical care (London, England), 2004, Volume: 8, Issue:2 Topics: Acute Disease; Airway Resistance; Animals; Bronchial Spasm; Bronchoconstrictor Agents; Diaphragm; Dogs; Exhalation; Inhalation; Methacholine Chloride; Models, Animal; Positive-Pressure Respiration; Respiratory Mechanics; Work of Breathing	2004
Airway hyperresponsiveness by methacholine challenge testing following negative exercise challenge. The Journal of asthma : official journal of the Association for the Care of Asthma, 2004, Volume: 41, Issue:5 Topics: Adult; Bronchial Spasm; Bronchoconstrictor Agents; Exercise Test; False Negative Reactions; Female; Humans; Male; Methacholine Chloride	2004
Biologically variable ventilation improves gas exchange and respiratory mechanics in a model of severe bronchospasm. Critical care medicine, 2007, Volume: 35, Issue:7 Topics: Animals; Bronchial Spasm; Cytokines; Least-Squares Analysis; Methacholine Chloride; Pulmonary Gas Exchange; Random Allocation; Respiration, Artificial; Respiratory Mechanics; Status Asthmaticus; Swine	2007
Protective action of combinations of diphenhydramine and aminophylline in fatal bronchospasm in guinea pigs due to mecholyl aerosol. The Journal of pharmacology and experimental therapeutics, 1948, Volume: 94, Issue:4 Topics: Aerosols; Aminophylline; Animals; Bronchial Spasm; Diphenhydramine; Guinea Pigs; Humans; Methacholine Chloride	1948
A comparative study of the action of various sympathomimetic amine aerosols in counteracting the dyspnea and bronchospasm induced by histamine and by acetyl-beta-methylcholine. The Journal of allergy, 1949, Volume: 20, Issue:2 Topics: Adrenal Glands; Aerosols; Asthma; Bronchial Spasm; Choline; Dyspnea; Histamine; Histamine Agents; Methacholine Chloride; Sympathomimetics; Tissue Extracts	1949
Actions of theophylline, terbutaline, and ipratropium bromide alone and in combinations on the methacholine induced bronchoconstriction in rats. Acta pharmacologica et toxicologica, 1982, Volume: 51, Issue:4 Topics: Animals; Atropine Derivatives; Bronchial Spasm; Bronchodilator Agents; Drug Interactions; Female; Heart Rate; Ipratropium; Methacholine Chloride; Methacholine Compounds; Rats; Rats, Inbred Strains; Terbutaline; Theophylline	1982
Bronchial hyperreactivity in chronic obstructive bronchitis. The American review of respiratory disease, 1983, Volume: 127, Issue:4 Topics: Bronchial Spasm; Bronchitis; Humans; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds	1983
Comparison of the tussive effects of histamine and methacholine in humans. Journal of applied physiology: respiratory, environmental and exercise physiology, 1983, Volume: 55, Issue:2 Topics: Adult; Aged; Asthma; Bronchial Spasm; Chronic Disease; Cough; Female; Histamine; Humans; Male; Metaproterenol; Methacholine Chloride; Methacholine Compounds; Middle Aged	1983
Mechanism of reduced maximum expiratory flow in methacholine-induced bronchoconstriction in dogs. Journal of applied physiology: respiratory, environmental and exercise physiology, 1983, Volume: 55, Issue:3 Topics: Airway Obstruction; Airway Resistance; Animals; Biomechanical Phenomena; Bronchial Spasm; Dogs; Forced Expiratory Flow Rates; Lung Volume Measurements; Maximal Midexpiratory Flow Rate; Methacholine Chloride; Methacholine Compounds	1983
Bronchial responsiveness to methacholine and effects of respiratory maneuvers. Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 56, Issue:1 Topics: Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Forced Expiratory Volume; Humans; Maximal Midexpiratory Flow Rate; Methacholine Chloride; Methacholine Compounds; Respiration	1984
Breathing pattern during induced bronchoconstriction. Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 56, Issue:4 Topics: Adult; Aerosols; Bronchial Spasm; Female; Humans; Male; Metaproterenol; Methacholine Chloride; Methacholine Compounds; Oxygen; Plethysmography; Respiration; Tidal Volume; Time Factors	1984
Relationship between regional ventilation and aerosol deposition in tidal breathing. The American review of respiratory disease, 1984, Volume: 130, Issue:1 Topics: Adult; Aerosols; Aged; Animals; Bronchial Spasm; Computers; Dogs; Female; Humans; Lung Diseases; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Pulmonary Ventilation; Respiration; Xenon Radioisotopes	1984
Effects of bronchoconstriction on breathing during normoxia and hypoxia in anesthetized cats. Respiration physiology, 1984, Volume: 57, Issue:1 Topics: Anesthesia; Animals; Bronchial Spasm; Cats; Diaphragm; Electromyography; Hypoxia; Methacholine Chloride; Methacholine Compounds; Physiology; Respiration; Tidal Volume; Vagotomy	1984
Ozone-induced changes in muscarinic bronchial reactivity by different testing methods. Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 57, Issue:6 Topics: Acetylcholine; Aerosols; Airway Resistance; Animals; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Dose-Response Relationship, Drug; Guinea Pigs; Infusions, Parenteral; Male; Methacholine Chloride; Methacholine Compounds; Muscarine; Ozone; Time Factors	1984
On the mechanism of histamine-induced bronchodilation in conscious guinea-pigs. Agents and actions, 1984, Volume: 15, Issue:3-4 Topics: Aerosols; Animals; Bronchial Spasm; Bronchodilator Agents; Chlorpheniramine; Cimetidine; Guinea Pigs; Histamine; Histamine Antagonists; Male; Methacholine Chloride; Methacholine Compounds; Metiamide; Propranolol; Receptors, Histamine H1	1984
Calcium channel blocking agents in bronchial hyperreactivity. The Journal of asthma : official journal of the Association for the Care of Asthma, 1984, Volume: 21, Issue:6 Topics: Airway Resistance; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchial Spasm; Calcium Channel Blockers; Cold Temperature; Histamine; Humans; Methacholine Chloride; Methacholine Compounds; Nifedipine; Verapamil	1984
Contribution of residual volume to the increased alveolar plateau with bronchoconstriction. Respiration; international review of thoracic diseases, 1982, Volume: 43, Issue:3 Topics: Adult; Bronchial Spasm; Female; Humans; Lung Volume Measurements; Male; Methacholine Chloride; Methacholine Compounds; Nitrogen; Pulmonary Alveoli; Residual Volume; Respiration; Respiratory Function Tests	1982
Passive immunization with an anti-substance P antibody prevents substance P- and neurokinin A-induced bronchospasm in anesthetized guinea-pigs. Life sciences, 1995, Volume: 57, Issue:2 Topics: Amino Acid Sequence; Anesthesia; Animals; Antibodies, Monoclonal; Antibody Specificity; Bronchial Spasm; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Immunization, Passive; Methacholine Chloride; Mice; Molecular Sequence Data; Neurokinin A; Rats; Substance P	1995
Influence of lung volume on collateral resistance during methacholine-induced bronchospasm. European journal of clinical investigation, 1994, Volume: 24, Issue:12 Topics: Adult; Airway Resistance; Asthma; Bronchial Spasm; Female; Forced Expiratory Volume; Humans; Lung; Male; Methacholine Chloride	1994
Perceived symptoms and discomfort during induced bronchospasm: the role of temporal adaptation and anxiety. Behaviour research and therapy, 1994, Volume: 32, Issue:6 Topics: Adaptation, Psychological; Adult; Anxiety; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Sick Role	1994
Bronchodilator reversal of bronchospasm and symptoms incurred during methacholine bronchoprovocation challenge. Documentation of safety and time course. Chest, 1993, Volume: 104, Issue:5 Topics: Adolescent; Adult; Aged; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Agents; Child; Cough; Dyspnea; Evaluation Studies as Topic; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Prospective Studies; Safety; Spirometry; Time Factors	1993
Evaluation of a worker with possible formaldehyde-induced asthma. The Journal of allergy and clinical immunology, 1993, Volume: 92, Issue:1 Pt 1 Topics: Asthma; Bronchial Provocation Tests; Bronchial Spasm; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Formaldehyde; Humans; Immunoglobulin E; Immunoglobulin G; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Skin Tests; Time Factors	1993
Inhaled nitric oxide. A bronchodilator in mild asthmatics with methacholine-induced bronchospasm. American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:1 Topics: Administration, Inhalation; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchoconstrictor Agents; Bronchodilator Agents; Female; Forced Expiratory Volume; Humans; Isoproterenol; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Respiratory Function Tests; Spirometry	1996
Antibronchospasmic, tachycardiac, and hypokalaemic effects of L-isoproterenol in guinea-pigs. Biopharmaceutics & drug disposition, 1995, Volume: 16, Issue:9 Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Bronchial Spasm; Bronchoconstrictor Agents; Bronchodilator Agents; Cardiotonic Agents; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate; Hypokalemia; Infusions, Intravenous; Isoproterenol; Male; Methacholine Chloride; Potassium; Pressure; Respiration; Stereoisomerism; Sympathomimetics; Tachycardia	1995
Airway hyper- or hyporeactivity to inhaled spasmogens 24 h after ovalbumin challenge of sensitized guinea-pigs. British journal of pharmacology, 1995, Volume: 116, Issue:5 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Administration, Inhalation; Airway Resistance; Animals; Asthma; Atropine; Bronchial Spasm; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Methacholine Chloride; Ovalbumin; Plethysmography, Whole Body; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents	1995
Tracheal gas insufflation improves ventilatory efficiency during metacholine-induced bronchospasm. Journal of critical care, 1997, Volume: 12, Issue:1 Topics: Animals; Bronchial Spasm; Bronchoconstrictor Agents; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Hemodynamics; Insufflation; Methacholine Chloride; Oxygen Inhalation Therapy; Pulmonary Gas Exchange; Respiration, Artificial; Trachea	1997
[Study of spontaneous resolution of bronchial spasm after methacholine challenge. Comparison of patients with different degree of hyperreactivity]. Recenti progressi in medicina, 1997, Volume: 88, Issue:3 Topics: Adult; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Bronchial Spasm; Bronchoconstrictor Agents; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Time Factors	1997
Bradykinin-induced bronchospasm in the rat in vivo: a role for nitric oxide modulation. The European respiratory journal, 1999, Volume: 13, Issue:2 Topics: Airway Resistance; Animals; Bradykinin; Bradykinin Receptor Antagonists; Bronchial Provocation Tests; Bronchial Spasm; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Lung Compliance; Male; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley	1999
Bronchoconstrictor reactivity to NKA in allergic dogs: a comparison to histamine and methacholine. Pulmonary pharmacology & therapeutics, 2001, Volume: 14, Issue:2 Topics: Administration, Inhalation; Aerosols; Animals; Bronchial Hyperreactivity; Bronchial Spasm; Bronchoconstriction; Dogs; Female; Histamine; Hypersensitivity; Male; Methacholine Chloride; Neurokinin A	2001
Comparison of the anti-bronchoconstrictor activities of inhaled formoterol, its (R,R)- and (S,S)-enantiomers and salmeterol in the rhesus monkey. Pulmonary pharmacology & therapeutics, 2001, Volume: 14, Issue:4 Topics: Administration, Inhalation; Airway Resistance; Albuterol; Animals; Bronchial Spasm; Bronchoconstrictor Agents; Bronchodilator Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanolamines; Formoterol Fumarate; Macaca mulatta; Male; Methacholine Chloride; Salmeterol Xinafoate; Tachycardia	2001
Blood eosinophil counts for the prediction of the severity of exercise-induced bronchospasm in asthma. Respiratory medicine, 2002, Volume: 96, Issue:2 Topics: Adolescent; Adult; Asthma, Exercise-Induced; Biomarkers; Bronchial Spasm; Bronchoconstrictor Agents; Chi-Square Distribution; Eosinophils; Exercise Test; Humans; Immunoglobulin E; Leukocyte Count; Male; Methacholine Chloride; Regression Analysis; Skin Tests	2002
Airway and tissue mechanics in a murine model of asthma: alveolar capsule vs. forced oscillations. Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 93, Issue:1 Topics: Administration, Inhalation; Airway Resistance; Algorithms; Animals; Asthma; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Elasticity; Female; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Pulmonary Alveoli; Respiration, Artificial; Respiratory Function Tests; Respiratory Mechanics; Respiratory System	2002
Efficacy of anticholinergic and beta-adrenergic agonist treatment of maximal cholinergic bronchospasm in tracheally intubated rabbits. Anesthesia and analgesia, 1992, Volume: 75, Issue:5 Topics: Adrenergic beta-Agonists; Animals; Atropine; Bronchial Spasm; Intubation, Intratracheal; Lung Compliance; Methacholine Chloride; Parasympatholytics; Rabbits	1992
Aspirin-induced asthma and bronchial hyperresponsiveness. Allergie et immunologie, 1991, Volume: 23, Issue:10 Topics: Adolescent; Adult; Airway Resistance; Angioedema; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchial Spasm; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Humans; Lysine; Male; Methacholine Chloride; Middle Aged; Urticaria	1991
Accidental methacholine bronchoprovocation in a laboratory worker. Chest, 1991, Volume: 99, Issue:4 Topics: Adult; Bronchial Provocation Tests; Bronchial Spasm; Female; Humans; Methacholine Chloride; Occupational Exposure; Respiratory Therapy	1991
Bronchial response to methacholine in "healthy" children of asthmatic parents. Effect of treatment with cromolyn sodium. Chest, 1990, Volume: 97, Issue:2 Topics: Adolescent; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Child; Cromolyn Sodium; Dose-Response Relationship, Drug; Female; Humans; Methacholine Chloride; Methacholine Compounds; Respiratory Function Tests	1990
Bronchial responsiveness after human heart-lung transplantation. Chest, 1990, Volume: 97, Issue:6 Topics: Adult; Albuterol; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Female; Heart-Lung Transplantation; Humans; Ipratropium; Male; Methacholine Chloride; Methacholine Compounds; Propranolol; Receptors, Muscarinic; Time Factors	1990
Bronchial responsiveness in patients with mitral valve disease. The European respiratory journal, 1990, Volume: 3, Issue:2 Topics: Bronchial Provocation Tests; Bronchial Spasm; Dyspnea, Paroxysmal; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Mitral Valve Insufficiency; Mitral Valve Stenosis; Spirometry	1990
Acute bronchoconstriction is not a stimulus for sympatho-adrenal activation in asthmatic or healthy subjects. The European respiratory journal, 1990, Volume: 3, Issue:3 Topics: Acute Disease; Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Epinephrine; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Neuropeptide Y; Norepinephrine; Reference Values; Respiratory Function Tests	1990
Increased bronchial responsiveness in primary and secondary Sjögren's syndrome. The European respiratory journal, 1990, Volume: 3, Issue:5 Topics: Bronchial Provocation Tests; Bronchial Spasm; Connective Tissue Diseases; Humans; Lung Volume Measurements; Methacholine Chloride; Methacholine Compounds; Middle Aged; Pulmonary Diffusing Capacity; Sjogren's Syndrome	1990
Mechanisms of hyperinflation in asthma. The European respiratory journal, 1990, Volume: 3, Issue:6 Topics: Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Forced Expiratory Volume; Humans; Lung; Lung Compliance; Lung Volume Measurements; Male; Methacholine Chloride; Methacholine Compounds; Respiratory Mechanics; Respiratory Muscles; Ventilators, Mechanical	1990
Comparative effects of volume history on bronchoconstriction induced by hyperventilation and methacholine in asthmatic subjects. The European respiratory journal, 1990, Volume: 3, Issue:6 Topics: Asthma; Bronchial Provocation Tests; Bronchial Spasm; Cold Temperature; Forced Expiratory Volume; Humans; Hyperventilation; Lung Compliance; Methacholine Chloride; Methacholine Compounds; Middle Aged	1990
Increased metachromatic cells and lymphocytes in bronchoalveolar lavage fluid of dogs with airway hyperreactivity. The American review of respiratory disease, 1986, Volume: 133, Issue:3 Topics: Animals; Body Fluids; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Citrates; Citric Acid; Cytoplasmic Granules; Disease Models, Animal; Dog Diseases; Dogs; Histamine; Leukocyte Count; Leukocytes; Mast Cells; Methacholine Chloride; Methacholine Compounds; Pulmonary Alveoli; Staining and Labeling; Therapeutic Irrigation	1986
Airway hyperreactivity in patients undergoing lung and heart/lung transplantation. The American review of respiratory disease, 1989, Volume: 139, Issue:4 Topics: Adolescent; Adult; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Female; Heart Transplantation; Heart-Lung Transplantation; Histamine; Humans; Lung; Lung Transplantation; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged	1989
Lung rejection and bronchial hyperresponsiveness to methacholine and ultrasonically nebulized distilled water in heart-lung transplantation patients. The American review of respiratory disease, 1989, Volume: 140, Issue:1 Topics: Adult; Aerosols; Asthma; Biopsy; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Denervation; Female; Graft Rejection; Heart Transplantation; Heart-Lung Transplantation; Humans; Lung; Lung Transplantation; Male; Methacholine Chloride; Methacholine Compounds; Pulmonary Circulation; Water	1989
Significant changes in nonspecific bronchial responsiveness after isolated immediate bronchospecific reactions caused by isocyanates but not after a late reaction caused by plicatic acid. The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:1 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Cyanates; Forced Expiratory Volume; Histamine; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Isocyanates; Lignans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Naphthols; Occupational Diseases	1989
Individual differences in regional deposition of 6-micron particles in humans with induced bronchoconstriction. Experimental lung research, 1989, Volume: 15, Issue:1 Topics: Administration, Inhalation; Airway Resistance; Bronchial Spasm; Humans; Individuality; Lung; Methacholine Chloride; Methacholine Compounds; Models, Biological; Particle Size; Peak Expiratory Flow Rate; Polytetrafluoroethylene; Technetium; Time Factors	1989
Reversibility of induced bronchoconstriction by deep inspiration in asthmatic and normal subjects. The European respiratory journal, 1989, Volume: 2, Issue:4 Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Humans; Lung Volume Measurements; Male; Maximal Voluntary Ventilation; Methacholine Chloride; Methacholine Compounds; Peak Expiratory Flow Rate; Pulmonary Ventilation	1989
Effect of short esophageal acidification on airway hyperreactivity. Respiration; international review of thoracic diseases, 1989, Volume: 55, Issue:1 Topics: Administration, Inhalation; Adult; Asthma; Bronchial Spasm; Esophagus; Female; Humans; Hydrogen-Ion Concentration; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged	1989
Bronchial hyperresponsiveness to inhaled methacholine in subjects with chronic left heart failure at a time of exacerbation and after increasing diuretic therapy. Chest, 1989, Volume: 96, Issue:2 Topics: Aged; Bronchial Provocation Tests; Bronchial Spasm; Diuretics; Dyspnea, Paroxysmal; Female; Heart Failure; Humans; Lung Volume Measurements; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Pulmonary Edema	1989
Bronchial responsiveness to exercise after human cardiopulmonary transplantation. Chest, 1989, Volume: 96, Issue:2 Topics: Adolescent; Adult; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchial Spasm; Exercise Test; Female; Forced Expiratory Volume; Heart Transplantation; Humans; Lung Transplantation; Male; Methacholine Chloride; Methacholine Compounds; Physical Exertion; Pulmonary Ventilation; Time Factors	1989
Effect of nedocromil sodium on adenosine- and methacholine-induced bronchospasm in asthma. Clinical allergy, 1987, Volume: 17, Issue:2 Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Nedocromil; Quinolines	1987
[Increased lung volume in inhalant provocation]. Praxis und Klinik der Pneumologie, 1988, Volume: 42 Suppl 1 Topics: Bronchial Provocation Tests; Bronchial Spasm; Humans; Lung; Lung Volume Measurements; Methacholine Chloride; Methacholine Compounds; Thorax	1988
Usefulness and safety of pharmacologic bronchoprovocation challenge in evaluating patients with normal spirometric tests who are suspected of having asthma. Chest, 1988, Volume: 93, Issue:5 Topics: Asthma; Bronchial Provocation Tests; Bronchial Spasm; Histamine; Humans; Methacholine Chloride; Methacholine Compounds; Spirometry	1988
Non-pharmacological modulators of airway responsiveness. Progress in clinical and biological research, 1988, Volume: 263 Topics: Acetylcholine; Aerosols; Airway Resistance; Animals; Asthma; Bronchial Spasm; Humans; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Nicotiana; Plants, Toxic; Pulmonary Ventilation; Smoke	1988
A new method of inhalation challenge with propranolol: comparison with methacholine-induced bronchoconstriction and role of vagal nerve activity. The Journal of allergy and clinical immunology, 1987, Volume: 80, Issue:3 Pt 1 Topics: Adolescent; Adult; Airway Resistance; Atropine; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Propranolol; Vagus Nerve	1987
In vivo functional antagonism between isoproterenol and bronchoconstrictants in the dog. Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:2 Topics: Airway Resistance; Animals; Bronchial Spasm; Bronchodilator Agents; Dogs; Dose-Response Relationship, Drug; Histamine; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Serotonin	1987
Bronchial responsiveness to methacholine during airway cooling in normal subjects. Clinical allergy, 1986, Volume: 16, Issue:1 Topics: Adult; Bronchial Provocation Tests; Bronchial Spasm; Cold Temperature; Dose-Response Relationship, Drug; Forced Expiratory Flow Rates; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Pulmonary Ventilation	1986
Regional deposition of particles in human lung after induced bronchoconstriction. Experimental lung research, 1986, Volume: 10, Issue:3 Topics: Adult; Airway Resistance; Bronchial Spasm; Female; Humans; Lung; Male; Methacholine Chloride; Methacholine Compounds; Particle Size; Polytetrafluoroethylene; Regression Analysis; Respiration; Tissue Distribution	1986
Factors that contribute to inhibition of methacholine-induced bronchoconstriction. The American review of respiratory disease, 1986, Volume: 133, Issue:5 Topics: Adult; Asthma; Bronchi; Bronchial Spasm; Female; Humans; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds	1986
Characterization of the airway response to inhaled leukotriene D4 in normal subjects. The American review of respiratory disease, 1986, Volume: 133, Issue:6 Topics: Adult; Aerosols; Airway Resistance; Bronchial Provocation Tests; Bronchial Spasm; Dose-Response Relationship, Drug; Humans; Immunization; Male; Methacholine Chloride; Methacholine Compounds; Reference Values; Respiratory System; SRS-A; Tachyphylaxis	1986
Effects of induced bronchoconstriction on pulmonary blood flow. Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 60, Issue:6 Topics: Adult; Biomechanical Phenomena; Bronchial Provocation Tests; Bronchial Spasm; Female; Hemodynamics; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Plant Extracts; Pulmonary Circulation; Respiratory Function Tests	1986
Increase in gastroesophageal reflux during methacholine-induced bronchospasm. The Journal of allergy and clinical immunology, 1986, Volume: 78, Issue:4 Pt 1 Topics: Adult; Asthma; Bronchial Spasm; Esophagus; Female; Gastroesophageal Reflux; Humans; Male; Methacholine Chloride; Methacholine Compounds; Pressure	1986
Laryngeal constriction in normal humans during experimentally induced bronchoconstriction. Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:2 Topics: Adult; Airway Resistance; Bronchial Provocation Tests; Bronchial Spasm; Female; Forced Expiratory Volume; Glottis; Histamine; Humans; Laryngismus; Male; Methacholine Chloride; Methacholine Compounds; Vital Capacity	1985
Central and local cholinergic components of histamine-induced bronchoconstriction in dogs. Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:2 Topics: Animals; Atropine; Bronchial Spasm; Dogs; Dose-Response Relationship, Drug; Female; Histamine; Lung; Lung Compliance; Male; Methacholine Chloride; Methacholine Compounds; Muscle, Smooth; Reflex; Vagotomy; Vagus Nerve	1985
Antigen sensitization and methacholine responses in dogs with hyperreactive airways. Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:2 Topics: Aerosols; Animals; Antigens, Helminth; Ascaris; Bronchial Spasm; Dogs; Enzyme-Linked Immunosorbent Assay; Immunization; Immunoglobulin E; Lung Compliance; Methacholine Chloride; Methacholine Compounds; Time Factors	1985
Comparison of metaproterenol, isoetharine and salbutamol in the relief of methacholine-induced bronchospasm in dogs. Canadian Anaesthetists' Society journal, 1985, Volume: 32, Issue:2 Topics: Airway Resistance; Albuterol; Amino Alcohols; Anesthesia; Animals; Bronchial Spasm; Dogs; Halothane; Hemodynamics; Isoetharine; Metaproterenol; Methacholine Chloride; Methacholine Compounds	1985
Laryngeal resistance immediately after panting in control and constricted airways. Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:4 Topics: Adult; Airway Resistance; Bronchial Spasm; Histamine; Humans; Larynx; Male; Methacholine Chloride; Methacholine Compounds; Physiology; Respiration; Tidal Volume	1985
The effect of age on methacholine response. The Journal of allergy and clinical immunology, 1985, Volume: 76, Issue:4 Topics: Adolescent; Adult; Aged; Aging; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Retrospective Studies	1985
Increased in vitro airway responsiveness in sheep following repeated exposure to antigen in vivo. Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 59, Issue:6 Topics: Animals; Antigens; Ascaris; Bronchial Spasm; Dinoprost; Histamine; Lung; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Prostaglandins F; Respiratory System; Sheep; Thromboxane A2; Trachea	1985
[Pharmacodynamic tests of bronchial hyperreactivity]. Anales espanoles de pediatria, 1985, Nov-30, Volume: 23, Issue:7 Topics: Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Agents; Humans; Methacholine Chloride; Methacholine Compounds; Parasympathetic Nervous System; Spirometry; Sympathetic Nervous System	1985
The effects of acute bronchoconstriction on respiratory activity in patients with chronic obstructive pulmonary disease. The American review of respiratory disease, 1985, Volume: 131, Issue:2 Topics: Aged; Airway Resistance; Bronchial Provocation Tests; Bronchial Spasm; Carbon Dioxide; Humans; Hyperventilation; Lung Compliance; Lung Diseases, Obstructive; Methacholine Chloride; Methacholine Compounds; Middle Aged; Pulmonary Gas Exchange; Respiration; Tidal Volume; Ventilation-Perfusion Ratio	1985
Calcium chelators increase airway responsiveness. Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 59, Issue:1 Topics: Aerosols; Airway Resistance; Animals; Bronchial Provocation Tests; Bronchial Spasm; Calcium; Chelating Agents; Dogs; Dose-Response Relationship, Drug; Edetic Acid; Methacholine Chloride; Methacholine Compounds; Premedication	1985